Exogenously administered secreted frizzled related protein 2 (Sfrp2) reduces fibrosis and improves cardiac function in a rat model of myocardial infarction

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 49, 2010, Pages 21110-21115

  He, Wei ^a   Zhang, Lunan ^a   Ni, Aiguo ^a   Zhang, Zhiping ^a   Mirotsou, Maria ^a   Mao, Lan ^a   Pratt, Richard E ^a   Dzau, Victor J ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; PROCOLLAGEN; PROCOLLAGEN C PROTEINASE; RECOMBINANT SECRETED FRIZZLED RELATED PROTEIN 1; RECOMBINANT SECRETED FRIZZLED RELATED PROTEIN 2; RECOMBINANT SECRETED FRIZZLED RELATED PROTEIN 3; SECRETED FRIZZLED RELATED PROTEIN 1; SECRETED FRIZZLED RELATED PROTEIN 2; UNCLASSIFIED DRUG;

ACUTE HEART INFARCTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; FIBROBLAST; HEART FUNCTION; HEART MUSCLE FIBROSIS; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ANIMALS; BONE MORPHOGENETIC PROTEIN 1; COLLAGEN TYPE I; DISEASE MODELS, ANIMAL; FIBROSIS; FRIZZLED RECEPTORS; HUMANS; MALE; MEMBRANE PROTEINS; MYOCARDIAL INFARCTION; RATS; RATS, SPRAGUE-DAWLEY; UP-REGULATION; VENTRICULAR DYSFUNCTION, LEFT; VENTRICULAR FUNCTION, LEFT;

MAMMALIA; RATTUS;

EID: 78650489190     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1004708107     Document Type: Article

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