Cornelia de Lange Syndrome: NIPBL haploinsufficiency downregulates canonical Wnt pathway in zebrafish embryos and patients fibroblasts

Cell Death and Disease

Volumn 4, Issue 10, 2013, Pages

  Pistocchi, A ^a   Fazio, G ^b   Cereda, A ^b   Ferrari, L ^a   Bettini, L R ^b   Messina, G ^a   Cotelli, F ^a   Biondi, A ^b   Selicorni, A ^b   Massa, V ^b  

^a UNIVERSITY OF MILAN   (Italy)

^b SAN GERARDO HOSPITAL   (Italy)

Author keywords

Apoptosis; Cornelia de Lange Syndrome; Cyclins; Fibroblasts; NIPBL; Zebrafish

Indexed keywords

CYCLIN D1;

ANIMAL EMBRYO; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL FUNCTION; CELL MATURATION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DE LANGE SYNDROME; DOWN REGULATION; EMBRYO; FIBROBLAST; GENE ACTIVATION; GENE SILENCING; HAPLOINSUFFICIENCY; HUMAN; HUMAN CELL; HUMAN TISSUE; LOSS OF FUNCTION MUTATION; NERVE CELL; NERVE CELL DIFFERENTIATION; NERVOUS TISSUE; NIPPED B LIKE GENE; NONHUMAN; PARALOGY; PHENOTYPE; PRIORITY JOURNAL; RHOMBENCEPHALON; WNT SIGNALING PATHWAY; ZEBRA FISH;

ANIMALS; APOPTOSIS; CELL PROLIFERATION; CELL SURVIVAL; CENTRAL NERVOUS SYSTEM; CHILD; DE LANGE SYNDROME; DISEASE MODELS, ANIMAL; DOWN-REGULATION; EMBRYO, NONMAMMALIAN; FEMALE; FIBROBLASTS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE KNOCKDOWN TECHNIQUES; HAPLOINSUFFICIENCY; HUMANS; MALE; MORPHOLINOS; PHENOTYPE; PROTEINS; WNT SIGNALING PATHWAY; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 84887486685     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2013.371     Document Type: Article

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