Change in gene expression profiles of secreted frizzled-related proteins (SFRPs) by sodium butyrate in gastric cancers: Induction of promoter demethylation and histone modification causing inhibition of Wnt signaling

International Journal of Oncology

Volumn 40, Issue 5, 2012, Pages 1533-1542

  Shin, Hyunsoo ^a   Kim, Jie Hyun ^a   Lee, Yeo Song ^a   Lee, Yong Chan ^a  

^a Yonsei University College of Medicine   (South Korea)

Author keywords

DNA methylation; Histone modification; SFRP; Sodium butyrate; Wnt signal

Indexed keywords

BETA CATENIN; BUTYRIC ACID; DNA METHYLTRANSFERASE INHIBITOR; SECRETED FRIZZLED RELATED PROTEIN 1; SECRETED FRIZZLED RELATED PROTEIN 2; WNT PROTEIN;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER TISSUE; CELL PROLIFERATION; CONTROLLED STUDY; DEMETHYLATION; EPIGENETICS; GENE EXPRESSION PROFILING; GENE SILENCING; HISTONE MODIFICATION; HUMAN; HUMAN CELL; HUMAN TISSUE; INHIBITION KINETICS; METHYLATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; STOMACH CANCER;

ADULT; AGED; AGED, 80 AND OVER; ANTINEOPLASTIC AGENTS; APOPTOSIS; AZACITIDINE; BETA CATENIN; BUTYRATES; CELL LINE, TUMOR; CELL PROLIFERATION; DNA METHYLATION; DNA MODIFICATION METHYLASES; DOWN-REGULATION; EPIGENESIS, GENETIC; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, REPORTER; HISTONE DEACETYLASE INHIBITORS; HISTONES; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MEMBRANE PROTEINS; MIDDLE AGED; PROMOTER REGIONS, GENETIC; STOMACH NEOPLASMS; TRANSFECTION; WNT SIGNALING PATHWAY;

EID: 84860271216     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2012.1327     Document Type: Article

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