Canonical Wnt/β-catenin signaling in epicardial fibrosis of failed pediatric heart allografts with diastolic dysfunction

Cardiovascular Pathology

Volumn 22, Issue 1, 2013, Pages 54-57

  Ye, Bo ^a   Ge, Yao ^a   Perens, Gregory ^b   Hong, Longsheng ^b   Xu, Haodong ^a   Fishbein, Michael C ^b   Li, Faqian ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Catenin; Allograft; Epicardium; Fibrosis; Heart failure; Heart transplant; LEF TCF; Pediatric; Wnt signaling

Indexed keywords

BETA CATENIN; LYMPHOID ENHANCER FACTOR 1; PROTEIN T CELL FACTOR 3; PROTEIN T CELL FACTOR 4; T CELL FACTOR PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL TYPE; CLINICAL ARTICLE; CONTROLLED STUDY; DIASTOLIC DYSFUNCTION; EPICARDIUM; EXPLANT; FIBROBLAST; GRAFT FAILURE; HEART MUSCLE FIBROSIS; HEART TRANSPLANTATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL; PROTEIN EXPRESSION; WNT SIGNALING PATHWAY;

BETA CATENIN; CASE-CONTROL STUDIES; DIASTOLE; FIBROBLASTS; FIBROSIS; HEART TRANSPLANTATION; HUMANS; IMMUNOHISTOCHEMISTRY; PERICARDIUM; TRANSCRIPTION FACTOR 7-LIKE 2 PROTEIN; TREATMENT FAILURE; VENTRICULAR DYSFUNCTION; VENTRICULAR FUNCTION; WNT SIGNALING PATHWAY;

EID: 84870915167     PISSN: 10548807     EISSN: 18791336     Source Type: Journal    
DOI: 10.1016/j.carpath.2012.03.004     Document Type: Article

References (22)

1. R Kirk, LB Edwards, P Aurora, DO Taylor, J Christie, and F Dobbels Registry of the International Society for Heart and Lung Transplantation: Eleventh Official Pediatric Heart Transplantation Report - 2008 J Heart Lung Transplant 27 2008 970 977
2. E Pahl, DC Naftel, MA Kuhn, RE Shaddy, WR Morrow, and CE Canter The impact and outcome of transplant coronary artery disease in a pediatric population: a 9-year multi-institutional study J Heart Lung Transplant 24 2005 645 651 (Pubitemid 40798245)
3. G Perens, F Li, S Meier, R Kaur, JC Alejos, and M Fishbein Clinico-pathologic findings in end-stage pediatric heart transplant grafts Pediatr Transplant 13 2009 887 891
4. BA Alman, C Li, ME Pajerski, S Diaz-Cano, and HJ Wolfe Increased beta-catenin protein and somatic APC mutations in sporadic aggressive fibromatoses (desmoid tumors) Am J Pathol 151 1997 329 334 (Pubitemid 27330053)
5. SS Cheon, AY Cheah, S Turley, P Nadesan, R Poon, and H Clevers beta-Catenin stabilization dysregulates mesenchymal cell proliferation, motility, and invasiveness and causes aggressive fibromatosis and hyperplastic cutaneous wounds Proc Natl Acad Sci U S A 99 2002 6973 6978 (Pubitemid 34526242)
6. WM Blankesteijn, ME van Gijn, YP Essers-Janssen, MJ Daemen, and JF Smits Beta-catenin, an inducer of uncontrolled cell proliferation and migration in malignancies, is localized in the cytoplasm of vascular endothelium during neovascularization after myocardial infarction Am J Pathol 157 2000 877 883 (Pubitemid 32109380)
7. M Chilosi, V Poletti, A Zamo, M Lestani, L Montagna, and P Piccoli Aberrant Wnt/{beta}-catenin pathway activation in idiopathic pulmonary fibrosis Am J Pathol 162 2003 1495 1502 (Pubitemid 36512831)
8. S Kishida, H Yamamoto, S Ikeda, M Kishida, I Sakamoto, and S Koyama Axin, a negative regulator of the wnt signaling pathway, directly interacts with adenomatous polyposis coli and regulates the stabilization of beta-catenin J Biol Chem 273 1998 10823 10826 (Pubitemid 28204914)
9. JR Miller, and RT Moon Signal transduction through beta-catenin and specification of cell fate during embryogenesis Genes Dev 10 1996 2527 2539 (Pubitemid 26357220)
10. J Behrens, JP von Kries, M Kuhl, L Bruhn, D Wedlich, and R Grosschedl Functional interaction of beta-catenin with the transcription factor LEF-1 Nature 382 1996 638 642 (Pubitemid 26268958)
11. XP Yi, AM Gerdes, and F Li Myocyte redistribution of GRK2 and GRK5 in hypertensive, heart-failure-prone rats Hypertension 39 2002 1058 1063 (Pubitemid 34620124)
12. C Doglioni, S Piccinin, S Demontis, MG Cangi, L Pecciarini, and C Chiarelli Alterations of β-catenin pathway in non-melanoma skin tumors: loss of α-ABC nuclear reactivity correlates with the presence of β-catenin gene mutation Am J Pathol 163 2003 2277 2287 (Pubitemid 37466472)
13. M Oosterwegel, M van de Wetering, D Dooijes, L Klomp, A Winoto, and K Georgopoulos Cloning of murine TCF-1, a T cell-specific transcription factor interacting with functional motifs in the CD3-epsilon and T cell receptor alpha enhancers J Exp Med 173 1991 1133 1142
14. A Travis, A Amsterdam, C Belanger, and R Grosschedl LEF-1, A gene encoding a lymphoid-specific protein with an HMG domain, regulates T-cell receptor alpha enhancer function [corrected] Genes Dev 5 1991 880 894 (Pubitemid 21906004)
15. S Verbeek, D Izon, F Hofhuis, E Robanus-Maandag, H te Riele, and Mvd Watering An HMG-box-containing T-cell factor required for thymocyte differentiation Nature 374 1995 70 74
16. J Castrop, D van Wichen, M Koomans-Bitter, M van de Wetering, R de Weger, and J van Dongen The human TCF-1 gene encodes a nuclear DNA-binding protein uniquely expressed in normal and neoplastic T-lineage lymphocytes Blood 86 1995 3050 3059
17. V Korinek, N Barker, K Willert, M Molenaar, J Roose, and G Wagenaar Two members of the Tcf family implicated in Wnt/beta-catenin signaling during embryogenesis in the mouse Mol Cell Biol 18 1998 1248 1256 (Pubitemid 28100888)
18. Y Lee, B Swencki, S Shoichet, and RA Shivdasani A possible role for the high mobility group box transcription factor Tcf-4 in vertebrate gut epithelial cell differentiation J Biol Chem 274 1999 1566 1572
19. N Barker, G Huls, V Korinek, and H Clevers Restricted high level expression of Tcf-4 protein in intestinal and mammary gland epithelium Am J Pathol 154 1999 29 35 (Pubitemid 29031608)
20. S Stewart, GL Winters, MC Fishbein, HD Tazelaar, J Kobashigawa, and J Abrams Revision of the 1990 Working Formulation for the Standardization of Nomenclature in the Diagnosis of Heart Rejection J Heart Lung Transplant 24 2005 1710 1720 (Pubitemid 41641841)
21. CD Tan, WM Baldwin, and ER Rodriguez Update on cardiac transplantation pathology Arch Pathol Lab Med 131 2007 1169 1191 (Pubitemid 47260523)
22. DJ Luthringer, JT Yamashita, LS Czer, A Trento, and MC Fishbein Nature and significance of epicardial lymphoid infiltrates in cardiac allografts J Heart Lung Transplant 14 1995 537 543