The Wnt5A/protein kinase C pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal transition

Journal of Biological Chemistry

Volumn 282, Issue 23, 2007, Pages 17259-17271

  Dissanayake, Samudra K ^a   Wade, Michael ^a   Johnson, Carrie E ^b,f   O'Connell, Michael P ^a   Leotlela, Poloko D ^a   French, Amanda D ^a   Shah, Kavita V ^c   Hewitt, Kyle J ^a,g   Rosenthal, Devin T ^a,h   Indig, Fred E ^a   Jiang, Yuan ^b,i   Nickoloff, Brian J ^d   Taub, Dennis D ^a   Trent, Jeffrey M ^e   Moon, Randall T ^c   Bittner, Michael ^e   Weeraratna, Ashani T ^a,j  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^d LOYOLA UNIVERSITY MEDICAL CENTER   (United States)

^e TRANSLATIONAL GENOMICS RESEARCH INSTITUTE   (United States)

^f DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g TUFTS UNIVERSITY   (United States)

^h UNIVERSITY OF MICHIGAN COMPREHENSIVE CANCER CENTER   (United States)

ⁱ NATIONAL CANCER INSTITUTE   (United States)

^j NATIONAL INSTITUTES OF HEALTH   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

CELLULAR PATHWAYS; EPITHELIAL TO MESENCHYMAL TRANSITION (EMT); MESENCHYMAL TRANSITION; METASTASIS SUPPRESSORS;

CELLS; ESTERS; GENE EXPRESSION; MICROARRAYS; RNA;

ENZYMES;

BETA CATENIN; KISS 1 PROTEIN; PHORBOL ESTER; PROTEIN KINASE C; RECOMBINANT PROTEIN; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR SNAIL; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; UVOMORULIN; VIMENTIN; WNT5A PROTEIN; ONCOPROTEIN; PRIMER DNA; WNT PROTEIN; WNT5A PROTEIN, HUMAN;

ARTICLE; CELL HOMING; CELL MOTILITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; EPITHELIUM; GENE EXPRESSION REGULATION; GENE FUNCTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MELANOMA; MELANOMA CELL; MESENCHYME; METASTASIS; METASTASIS INHIBITION; MICROARRAY ANALYSIS; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; UPREGULATION; CYTOLOGY; ENZYMOLOGY; EPITHELIUM CELL; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; MESODERM; METABOLISM; NUCLEOTIDE SEQUENCE; PATHOLOGY; TUMOR CELL LINE;

GASTROPODA;

BASE SEQUENCE; CELL LINE, TUMOR; DNA PRIMERS; EPITHELIAL CELLS; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; MELANOMA; MESODERM; NEOPLASM METASTASIS; PROTEIN KINASE C; PROTO-ONCOGENE PROTEINS; RNA, SMALL INTERFERING; WNT PROTEINS;

EID: 34447131518     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M700075200     Document Type: Article

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