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Volumn 34, Issue 3, 2014, Pages 433-440

The Wnt/planar cell polarity signaling pathway contributes to the integrity of tight junctions in brain endothelial cells

Author keywords

blood brain barrier; brain endothelial cells; planar cell polarity; tight junction; Wnt

Indexed keywords

BETA CATENIN; CELL PROTEIN; PAR PROTEIN; PROTEIN KINASE C; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; WNT PROTEIN; WNT5A PROTEIN;

EID: 84896725023     PISSN: 0271678X     EISSN: 15597016     Source Type: Journal    
DOI: 10.1038/jcbfm.2013.213     Document Type: Article
Times cited : (77)

References (40)
  • 3
    • 0019806209 scopus 로고
    • Membrane asymmetry in epithelia: Is the tight junction a barrier to diffusion in the plasma membrane?
    • Dragsten PR, Blumenthal R, Handler JS. Membrane asymmetry in epithelia: is the tight junction a barrier to diffusion in the plasma membrane? Nature 1981; 294: 718-722.
    • (1981) Nature , vol.294 , pp. 718-722
    • Dragsten, P.R.1    Blumenthal, R.2    Handler, J.S.3
  • 5
    • 2642614521 scopus 로고    scopus 로고
    • Junctional adhesion molecule, a novel member of the immunoglobulin superfamily that distributes at intercellular junctions and modulates monocyte transmigration
    • Martin-Padura I, Lostaglio S, Schneemann M, Williams L, Romano M, Fruscella P et al. Junctional adhesion molecule, a novel member of the immunoglobulin superfamily that distributes at intercellular junctions and modulates monocyte transmigration. J Cell Biol 1998; 142: 117-127.
    • (1998) J Cell Biol , vol.142 , pp. 117-127
    • Martin-Padura, I.1    Lostaglio, S.2    Schneemann, M.3    Williams, L.4    Romano, M.5    Fruscella, P.6
  • 6
    • 84860469139 scopus 로고    scopus 로고
    • Guanine nucleotide-binding protein Galphai2: A new partner of claudin-5 that regulates tight junction integrity in human brain endothelial cells
    • Luissint AC, Federici C, Guillonneau F, Chretien F, Camoin L, Glacial F et al. Guanine nucleotide-binding protein Galphai2: a new partner of claudin-5 that regulates tight junction integrity in human brain endothelial cells. J Cereb Blood Flow Metab 2012; 32: 860-873.
    • (2012) J Cereb Blood Flow Metab , vol.32 , pp. 860-873
    • Luissint, A.C.1    Federici, C.2    Guillonneau, F.3    Chretien, F.4    Camoin, L.5    Glacial, F.6
  • 7
    • 27744460321 scopus 로고    scopus 로고
    • Blood-brain barrier-specific properties of a human adult brain endothelial cell line
    • Weksler BB, Subileau EA, Perriere N, Charneau P, Holloway K, Leveque M et al. Blood-brain barrier-specific properties of a human adult brain endothelial cell line. FASEB J 2005; 19: 1872-1874.
    • (2005) FASEB J , vol.19 , pp. 1872-1874
    • Weksler, B.B.1    Subileau, E.A.2    Perriere, N.3    Charneau, P.4    Holloway, K.5    Leveque, M.6
  • 8
    • 84876161205 scopus 로고    scopus 로고
    • The hCMEC/D3 cell line as a model of the human blood brain barrier
    • Weksler B, Romero IA, Couraud PO. The hCMEC/D3 cell line as a model of the human blood brain barrier. Fluids Barriers CNS 2013; 10: 10-25.
    • (2013) Fluids Barriers CNS , vol.10 , pp. 10-25
    • Weksler, B.1    Romero, I.A.2    Couraud, P.O.3
  • 9
    • 84872233407 scopus 로고    scopus 로고
    • Tight junctions at the blood brain barrier: Physiological architecture and disease-Associated dysregulation
    • Luissint AC, Artus C, Glacial F, Ganeshamoorthy K, Couraud PO. Tight junctions at the blood brain barrier: physiological architecture and disease-Associated dysregulation. Fluids Barriers CNS 2012; 9: 23-34.
    • (2012) Fluids Barriers CNS , vol.9 , pp. 23-34
    • Luissint, A.C.1    Artus, C.2    Glacial, F.3    Ganeshamoorthy, K.4    Couraud, P.O.5
  • 10
    • 67650230896 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling: Components, mechanisms, and diseases
    • MacDonald BT, Tamai K, He X. Wnt/beta-catenin signaling: components, mechanisms, and diseases. Dev Cell 2009; 17: 9-26.
    • (2009) Dev Cell , vol.17 , pp. 9-26
    • Macdonald, B.T.1    Tamai, K.2    He, X.3
  • 11
    • 77958450885 scopus 로고    scopus 로고
    • The role of wnt signaling in physiological and pathological angiogenesis
    • Dejana E. The role of wnt signaling in physiological and pathological angiogenesis. Circ Res 2010; 107: 943-952.
    • (2010) Circ Res , vol.107 , pp. 943-952
    • Dejana, E.1
  • 14
    • 0141768242 scopus 로고    scopus 로고
    • The conditional inactivation of the beta-catenin gene in endothelial cells causes a defective vascular pattern and increased vascular fragility
    • Cattelino A, Liebner S, Gallini R, Zanetti A, Balconi G, Corsi A et al. The conditional inactivation of the beta-catenin gene in endothelial cells causes a defective vascular pattern and increased vascular fragility. J Cell Biol 2003; 162: 1111-1122.
    • (2003) J Cell Biol , vol.162 , pp. 1111-1122
    • Cattelino, A.1    Liebner, S.2    Gallini, R.3    Zanetti, A.4    Balconi, G.5    Corsi, A.6
  • 15
    • 84881180266 scopus 로고    scopus 로고
    • Wnt activation of immortalized brain endothelial cells as a tool for generating a standardized model of the blood brain barrier in vitro
    • Paolinelli R, Corada M, Ferrarini L, Devraj K, Artus C, Czupalla CJ et al. Wnt activation of immortalized brain endothelial cells as a tool for generating a standardized model of the blood brain barrier in vitro. PLoS ONE 2013; 8: e70233.
    • (2013) PLoS ONE , vol.8
    • Paolinelli, R.1    Corada, M.2    Ferrarini, L.3    Devraj, K.4    Artus, C.5    Czupalla, C.J.6
  • 16
    • 0041695485 scopus 로고    scopus 로고
    • A second canon Functions and mechanisms of beta-catenin-independent Wnt signaling
    • Veeman MT, Axelrod JD, Moon RT. A second canon. Functions and mechanisms of beta-catenin-independent Wnt signaling. Dev Cell 2003; 5: 367-377.
    • (2003) Dev Cell , vol.5 , pp. 367-377
    • Veeman, M.T.1    Axelrod, J.D.2    Moon, R.T.3
  • 17
    • 27744538492 scopus 로고    scopus 로고
    • Planar cell polarization: An emerging model points in the right direction
    • Klein TJ, Mlodzik M. Planar cell polarization: an emerging model points in the right direction. Annu Rev Cell Dev Biol 2005; 21: 155-176.
    • (2005) Annu Rev Cell Dev Biol , vol.21 , pp. 155-176
    • Klein, T.J.1    Mlodzik, M.2
  • 18
    • 34547604466 scopus 로고    scopus 로고
    • Cdc42 and noncanonical Wnt signal transduction pathways cooperate to promote cell polarity
    • Schlessinger K, McManus EJ, Hall A. Cdc42 and noncanonical Wnt signal transduction pathways cooperate to promote cell polarity. J Cell Biol 2007; 178: 355-361.
    • (2007) J Cell Biol , vol.178 , pp. 355-361
    • Schlessinger, K.1    McManus, E.J.2    Hall, A.3
  • 19
    • 0036828968 scopus 로고    scopus 로고
    • Regulated protein-protein interaction between aPKC and PAR-3 plays an essential role in the polarization of epithelial cells
    • Nagai-Tamai Y, Mizuno K, Hirose T, Suzuki A, Ohno S. Regulated protein-protein interaction between aPKC and PAR-3 plays an essential role in the polarization of epithelial cells. Genes Cells 2002; 7: 1161-1171.
    • (2002) Genes Cells , vol.7 , pp. 1161-1171
    • Nagai-Tamai, Y.1    Mizuno, K.2    Hirose, T.3    Suzuki, A.4    Ohno, S.5
  • 20
    • 74249091561 scopus 로고    scopus 로고
    • Beta1 integrin establishes endothelial cell polarity and arteriolar lumen formation via a Par3- dependent mechanism
    • Zovein AC, Luque A, Turlo KA, Hofmann JJ, Yee KM, Becker MS et al. Beta1 integrin establishes endothelial cell polarity and arteriolar lumen formation via a Par3- dependent mechanism. Dev Cell 2010; 18: 39-51.
    • (2010) Dev Cell , vol.18 , pp. 39-51
    • Zovein, A.C.1    Luque, A.2    Turlo, K.A.3    Hofmann, J.J.4    Yee, K.M.5    Becker, M.S.6
  • 21
    • 78149456928 scopus 로고    scopus 로고
    • The mouse bloodbrain barrier transcriptome: A new resource for understanding the development and function of brain endothelial cells
    • Daneman R, Zhou L, Agalliu D, Cahoy JD, Kaushal A, Barres BA. The mouse bloodbrain barrier transcriptome: a new resource for understanding the development and function of brain endothelial cells. PLoS ONE 2010; 5: e13741.
    • (2010) PLoS ONE , vol.5
    • Daneman, R.1    Zhou, L.2    Agalliu, D.3    Cahoy, J.D.4    Kaushal, A.5    Barres, B.A.6
  • 22
    • 67650079165 scopus 로고    scopus 로고
    • Meningococcal type IV pili recruit the polarity complex to cross the brain endothelium
    • Coureuil M, Mikaty G, Miller F, Lecuyer H, Bernard C, Bourdoulous S et al. Meningococcal type IV pili recruit the polarity complex to cross the brain endothelium. Science 2009; 325: 83-87.
    • (2009) Science , vol.325 , pp. 83-87
    • Coureuil, M.1    Mikaty, G.2    Miller, F.3    Lecuyer, H.4    Bernard, C.5    Bourdoulous, S.6
  • 23
    • 69449089689 scopus 로고    scopus 로고
    • Polarized P-glycoprotein expression by the immortalised human brain endothelial cell line, hCMEC/D3, restricts apical-To-basolateral permeability to rhodamine 123
    • Tai LM, Reddy PS, Lopez-Ramirez MA, Davies HA, Male DK, Loughlin AJ et al. Polarized P-glycoprotein expression by the immortalised human brain endothelial cell line, hCMEC/D3, restricts apical-To-basolateral permeability to rhodamine 123. Brain Res 2009; 1292: 14-24.
    • (2009) Brain Res , vol.1292 , pp. 14-24
    • Tai, L.M.1    Reddy, P.S.2    Lopez-Ramirez, M.A.3    Davies, H.A.4    Male, D.K.5    Loughlin, A.J.6
  • 24
    • 0033974507 scopus 로고    scopus 로고
    • Osmotic opening of the blood-brain barrier: Principles, mechanism, and therapeutic applications
    • Rapoport SI. Osmotic opening of the blood-brain barrier: principles, mechanism, and therapeutic applications. Cell Mol Neurobiol 2000; 20: 217-230.
    • (2000) Cell Mol Neurobiol , vol.20 , pp. 217-230
    • Rapoport, S.I.1
  • 25
    • 77951053765 scopus 로고    scopus 로고
    • Activation of the planar cell polarity formin DAAM1 leads to inhibition of endothelial cell proliferation, migration, and angiogenesis
    • Ju R, Cirone P, Lin S, Griesbach H, Slusarski DC, Crews CM. Activation of the planar cell polarity formin DAAM1 leads to inhibition of endothelial cell proliferation, migration, and angiogenesis. Proc Natl Acad Sci USA 2010; 107: 6906-6911.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 6906-6911
    • Ju, R.1    Cirone, P.2    Lin, S.3    Griesbach, H.4    Slusarski, D.C.5    Crews, C.M.6
  • 26
    • 0041470133 scopus 로고    scopus 로고
    • Dishevelled 2 recruits beta-Arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4
    • Chen W, ten Berge D, Brown J, Ahn S, Hu LA, Miller WE et al. Dishevelled 2 recruits beta-Arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4. Science 2003; 301: 1391-1394.
    • (2003) Science , vol.301 , pp. 1391-1394
    • Chen, W.1    Ten Berge, D.2    Brown, J.3    Ahn, S.4    Hu, L.A.5    Miller, W.E.6
  • 27
    • 77951911203 scopus 로고    scopus 로고
    • APKC phosphorylation of Bazooka defines the apical/lateral border in Drosophila epithelial cells
    • Morais-de-Sa E, Mirouse St V, Johnston D. aPKC phosphorylation of Bazooka defines the apical/lateral border in Drosophila epithelial cells. Cell 2010; 141: 509-523.
    • (2010) Cell , vol.141 , pp. 509-523
    • Morais-De-Sa, E.1    Mirouse St, V.2    Johnston, D.3
  • 29
    • 0037022122 scopus 로고    scopus 로고
    • Assembly of epithelial tight junctions is negatively regulated by Par6
    • Gao L, Joberty G, Macara IG. Assembly of epithelial tight junctions is negatively regulated by Par6. Curr Biol 2002; 12: 221-225.
    • (2002) Curr Biol , vol.12 , pp. 221-225
    • Gao, L.1    Joberty, G.2    Macara, I.G.3
  • 30
    • 33847154529 scopus 로고    scopus 로고
    • Cell polarity protein Par3 complexes with DNA-PK via Ku70 and regulates DNA double-strand break repair
    • Fang L, Wang Y, Du D, Yang G, Tak Kwok T, Kai Kong S et al. Cell polarity protein Par3 complexes with DNA-PK via Ku70 and regulates DNA double-strand break repair. Cell Res 2007; 17: 100-116.
    • (2007) Cell Res , vol.17 , pp. 100-116
    • Fang, L.1    Wang, Y.2    Du, D.3    Yang, G.4    Tak Kwok, T.5    Kai Kong, S.6
  • 31
    • 0034028065 scopus 로고    scopus 로고
    • Vivo assessment of the window of barrier opening after osmotic blood-brain barrier disruption in humans
    • Siegal T, Rubinstein R, Bokstein F, Schwartz A, Lossos A, Shalom E et al. In vivo assessment of the window of barrier opening after osmotic blood-brain barrier disruption in humans. J Neurosurg 2000; 92: 599-605.
    • (2000) J Neurosurg , vol.92 , pp. 599-605
    • Siegal, T.1    Rubinstein, R.2    Bokstein, F.3    Schwartz, A.4    Lossos, A.5    Shalom, E.6
  • 32
    • 0035817623 scopus 로고    scopus 로고
    • Junctional adhesion molecule (JAM) binds to PAR-3: A possible mechanism for the recruitment of PAR-3 to tight junctions
    • Itoh M, Sasaki H, Furuse M, Ozaki H, Kita T, Tsukita S. Junctional adhesion molecule (JAM) binds to PAR-3: a possible mechanism for the recruitment of PAR-3 to tight junctions. J Cell Biol 2001; 154: 491-497.
    • (2001) J Cell Biol , vol.154 , pp. 491-497
    • Itoh, M.1    Sasaki, H.2    Furuse, M.3    Ozaki, H.4    Kita, T.5    Tsukita, S.6
  • 33
  • 34
    • 77951888466 scopus 로고    scopus 로고
    • Dishevelled: The hub of Wnt signaling
    • Gao C, Chen YG. Dishevelled: the hub of Wnt signaling. Cell Signal 2010; 22: 717-727.
    • (2010) Cell Signal , vol.22 , pp. 717-727
    • Gao, C.1    Chen, Y.G.2
  • 36
    • 36249004436 scopus 로고    scopus 로고
    • Wnt5a-mediated noncanonical Wnt signalling regulates human endothelial cell proliferation and migration
    • Cheng CW, Yeh JC, Fan TP, Smith SK, Charnock-Jones DS. Wnt5a-mediated noncanonical Wnt signalling regulates human endothelial cell proliferation and migration. Biochem Biophys Res Commun 2008; 365: 285-290.
    • (2008) Biochem Biophys Res Commun , vol.365 , pp. 285-290
    • Cheng, C.W.1    Yeh, J.C.2    Fan, T.P.3    Smith, S.K.4    Charnock-Jones, D.S.5
  • 37
  • 38
    • 68849097853 scopus 로고    scopus 로고
    • Wnt/Planar cell polarity signaling: A new paradigm for cancer therapy
    • Wang Y. Wnt/Planar cell polarity signaling: a new paradigm for cancer therapy. Mol Cancer Ther 2009; 8: 2103-2109.
    • (2009) Mol Cancer Ther , vol.8 , pp. 2103-2109
    • Wang, Y.1


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