Mesenchymal stem cells overexpressing integrin-linked kinase attenuate cardiac fibroblast proliferation and collagen synthesis through paracrine actions

Molecular Medicine Reports

Volumn 7, Issue 5, 2013, Pages 1617-1623

  Mao, Qing ^a   Lin, Cheng Xi ^a   Liang, Xiu Lin ^b   Gao, Jian Shu ^a   Xu, Biao ^a  

^a MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

^b THE THIRD AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

Author keywords

Cardiac fibroblast; Gene therapy; Integrin linked kinase; Mesenchymal stem cell; Myocardial infarction

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN TYPE 3; CONNECTIVE TISSUE GROWTH FACTOR; GELATINASE A; GELATINASE B; INTEGRIN LINKED KINASE; METALLOPROTEINASE; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2;

ACUTE HEART INFARCTION; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL PROLIFERATION; COLLAGEN SYNTHESIS; CONTROLLED STUDY; CORONARY ARTERY LIGATION; ECHOCARDIOGRAPHY; FIBROBLAST; FIBROSING ALVEOLITIS; GENE EXPRESSION; GEOMETRY; HEART FUNCTION; HEART LEFT VENTRICLE EJECTION FRACTION; IN VITRO STUDY; IN VIVO STUDY; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MESENCHYMAL STEM CELL; MUSCLE CONTRACTILITY; NONHUMAN; PROTEIN EXPRESSION; RAT; VIRAL GENE DELIVERY SYSTEM;

ADENOVIRIDAE; ANIMALS; CELL PROLIFERATION; COLLAGEN; CULTURE MEDIA, CONDITIONED; CYTOKINES; ELECTROCARDIOGRAPHY; FIBROBLASTS; FIBROSIS; GENE EXPRESSION REGULATION; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; HEART FUNCTION TESTS; HUMANS; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELLS; MYOCARDIAL INFARCTION; MYOCARDIUM; PARACRINE COMMUNICATION; PHENOTYPE; PROTEIN-SERINE-THREONINE KINASES; RATS; RATS, SPRAGUE-DAWLEY; STROKE VOLUME; TRANSDUCTION, GENETIC; TRANSFECTION;

ANIMALIA;

EID: 84876002562     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2013.1348     Document Type: Article

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