Wnt signaling pathway in rheumatoid arthritis, with special emphasis on the different roles in synovial inflammation and bone remodeling

Cellular Signalling

Volumn 25, Issue 10, 2013, Pages 2069-2078

  Miao, Cheng Gui ^a,b   Yang, Ying Ying ^a   He, Xu ^a   Li, Xiao Feng ^a   Huang, Cheng ^a   Huang, Yan ^a   Zhang, Lei ^a   Lv, Xiong Wen ^a   Jin, Yong ^a   Li, Jun ^a  

^a ANHUI MEDICAL UNIVERSITY   (China)

^b ANHUI SCIENCE AND TECHNOLOGY UNIVERSITY   (China)

Author keywords

Dickkopf 1; Fibroblast like synoviocytes; Osteoblasts; Rheumatoid arthritis; Secreted frizzled related protein; Wnt signaling pathway

Indexed keywords

BETA CATENIN; CYCLIC CITRULLINATED PEPTIDE ANTIBODY; DICKKOPF 1 PROTEIN; FIBRONECTIN; FRIZZLED PROTEIN; GLYCOGEN SYNTHASE KINASE 3BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN G; INTERLEUKIN 6; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 5; MITOGEN ACTIVATED PROTEIN KINASE; OSTEOCLAST DIFFERENTIATION FACTOR; PROTEIN ARGININE DEIMINASE; PROTEIN ARGININE DEIMINASE 4; PROTEIN KINASE C; RECEPTOR TYROSINE KINASE LIKE ORPHAN RECEPTOR; RECEPTOR TYROSINE KINASE LIKE ORPHAN RECEPTOR 2; SECRETED FRIZZLED RELATED PROTEIN 1; STRESS ACTIVATED PROTEIN KINASE; STROMELYSIN; TOCILIZUMAB; TRANSCRIPTION FACTOR EZH2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1; VASCULOTROPIN; WNT1 PROTEIN; WNT5A PROTEIN;

AUTOIMMUNITY; BIOINFORMATICS; BONE REMODELING; CYTOKINE PRODUCTION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; EPIGENETICS; EZH2 GENE; FIBROBLAST LIKE SYNOVIOCYTE; GENE; HUMAN; INNATE IMMUNITY; JOINT DESTRUCTION; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR PATHOLOGY; NONHUMAN; OSTEOBLAST; OSTEOLYSIS; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN GLYCOSYLATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; REVIEW; RHEUMATOID ARTHRITIS; SYNOVIOCYTE; SYNOVITIS; UPREGULATION; WNT SIGNALING PATHWAY;

11Β-HSD1; 11BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1; ACPA; ADENOMATOUS POLYPOSIS COLI; ALPHA-KELCH-LIKE ECT2-INTERACTING PROTEIN; ALPHAKLEIP; ANTI-CITRULLINATED PEPTIDE ANTIBODY; APC; BMSC; BONE MARROW STROMAL CELL; CALMODULIN KINASE II; CAMKII; CASEIN KINASE 1; CK1; COLLAGEN TRIPLE-HELIX REPEAT-CONTAINING 1; CTHRC1; DICKKOPF-1; DISHEVELED; DKK1; DVL; EZH2; FGF; FIBROBLAST GROWTH FACTOR; FIBROBLAST-LIKE SYNOVIOCYTES; FLS; GLYCOGEN SYNTHASE KINASE 3Β; GSK3Β; HTERT; HUMAN TELOMERASE REVERSE TRANSCRIPTASE; ILGF-1; INSULIN LIKE GROWTH FACTOR-1; LEF; LIPOPOLYSACCHARIDE; LOW-DENSITY LIPOPROTEIN RECEPTOR PROTEIN; LPS; LRP; LYMPHOID ENHANCER BINDING FACTORS; MAPK; MATRIX METALLOPROTEINASES; MESENCHYMAL STEM CELLS; MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR; MICRORNA; MIRNA; MITF; MITOGEN-ACTIVATED PROTEIN; MMPS; MSCS; OSTEOBLASTS; PADI4; PAGET'S DISEASE OF THE BONE; PAR-2; PDB; PDGF; PEPTIDYLARGININE DEIMINASE-4; PKC; PLATELET DERIVED GROWTH FACTOR; PROTEIN KINASE C; PROTEINASE-ACTIVATED RECEPTOR-2; RA; RANKL; RECEPTOR ACTIVATOR OF NFΚB LIGAND; RECEPTOR TYROSINE KINASE-LIKE ORPHAN RECEPTOR 2; RHEUMATOID ARTHRITIS; RHO KINASE; ROK; ROR2; SDF-1; SECRETED FRIZZLED-RELATED PROTEIN; SFRP; STROMAL CELL DERIVED FACTOR 1; T-CELL FACTORS; T-CELL RECEPTOR; TCFS; TCR; VASCULAR CELL ADHESION MOLECULE-1; VASCULAR-ENDOTHELIAL GROWTH FACTOR; VCAM-1; VEGF; WNT SIGNALING PATHWAY; ZESTE HOMOLOGUE 2;

ARTHRITIS, RHEUMATOID; BONE REMODELING; CARTILAGE; HUMANS; INFLAMMATION; SYNOVIAL FLUID; WNT PROTEINS; WNT SIGNALING PATHWAY;

EID: 84880169315     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2013.04.002     Document Type: Review

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