Wnt-induced secreted protein-1 is a prohypertrophic and profibrotic growth factor

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 293, Issue 3, 2007, Pages

  Colston, J T ^a   De La Rosa, S D ^a   Koehler, M ^a   Gonzales, K ^a   Mestril, R ^b   Freeman, G L ^a,c   Bailey, S R ^a   Chandrasekar, B ^a,c,d  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b LOYOLA UNIVERSITY MEDICAL CENTER   (United States)

^c SOUTH TEXAS VETERANS HEALTH CARE SYSTEM   (United States)

^d Medicine/Cardiology   (United States)

Author keywords

Akt; Cardiomyocyte hypertrophy; Cysteine rich 61, connective tissue growth factor, and nephroblastoma overexpressed family; Myocardial infarction; Myocardial remodeling

Indexed keywords

BIGLYCAN; COLLAGEN; GROWTH FACTOR; INTERLEUKIN 1BETA; MESSENGER RNA; PROTEIN KINASE B; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; WNT INDUCED SECRETED PROTEIN 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL HYPERPLASIA; CELL PROLIFERATION; CELL STIMULATION; CONTROLLED STUDY; DNA SYNTHESIS; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FIBROBLAST; HEART INFARCTION; HEART LEFT VENTRICLE; HEART MUSCLE CELL; IN VIVO STUDY; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MALE; MITOGENESIS; MOUSE; NEWBORN; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; PROTEIN SYNTHESIS; QUANTITATIVE ANALYSIS; UPREGULATION; WESTERN BLOTTING;

ANIMALS; CELL PROLIFERATION; CELLS, CULTURED; DISEASE MODELS, ANIMAL; EXTRACELLULAR MATRIX PROTEINS; FIBROBLASTS; FIBROSIS; HYPERTROPHY; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MICE; MICE, INBRED C57BL; MYOCARDIAL INFARCTION; MYOCARDIUM; MYOCYTES, CARDIAC; ONCOGENE PROTEINS; PROTEOGLYCANS; RATS; RATS, SPRAGUE-DAWLEY; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 34548413245     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00428.2007     Document Type: Article

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