Stem cell factor gene transfer promotes cardiac repair after myocardial infarction via in situ recruitment and expansion of c-kit+ cells

Circulation Research

Volumn 111, Issue 11, 2012, Pages 1434-1445

  Yaniz Galende, Elisa ^a   Chen, Jiqiu ^a   Chemaly, Elie ^a   Liang, Lifan ^a   Hulot, Jean Sebastien ^a   McCollum, Latronya ^a   Arias, Teresa ^a   Fuster, Valentin ^a   Zsebo, Krisztina M ^b   Hajjar, Roger J ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b Celladon Corporation   (United States)

Author keywords

cardiac myocyte regeneration; gene transfer; myocardial infarction; stem cell factor

Indexed keywords

ACTIN; ADENOVIRUS VECTOR; ALPHA SARCOMERIC ACTIN; BETA CATENIN; BETA GALACTOSIDASE; BIOCHEMICAL MARKER; CASPASE 3; CD45 ANTIGEN; COLLAGEN TYPE 1; COLLAGEN TYPE 3; CYCLIN D1; CYCLINE; FC RECEPTOR; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; GLYCOGEN SYNTHASE KINASE 3BETA; NOTCH1 RECEPTOR; PHOSPHOHISTONE H3; PROCASPASE 3; PROTEIN HOXB4; PROTEIN MEF2; PROTEIN MEF2C; STEM CELL FACTOR; TRANSCRIPTION FACTOR GATA 4; TRANSCRIPTION FACTOR NKX2.5; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; WNT PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CARDIAC PROGENITOR CELL; CELL CYCLE; CELL EXPANSION; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; HEART FUNCTION; HEART HEMODYNAMICS; HEART INFARCTION; HEART INFARCTION SIZE; HEART MUSCLE CELL; HEART MUSCLE FIBROSIS; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; STEM CELL; TISSUE INJURY; TISSUE REGENERATION; TISSUE REPAIR; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY;

ADENOVIRIDAE; ANIMALS; BETA CATENIN; BLOTTING, WESTERN; CELL COUNT; CELL PROLIFERATION; GENE EXPRESSION; GENETIC THERAPY; HUMANS; KAPLAN-MEIER ESTIMATE; MALE; MICROSCOPY, CONFOCAL; MYOCARDIAL INFARCTION; MYOCARDIUM; MYOCYTES, CARDIAC; PROTO-ONCOGENE PROTEINS C-KIT; RATS; RATS, SPRAGUE-DAWLEY; REGENERATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STEM CELL FACTOR; STEM CELLS; WNT SIGNALING PATHWAY;

EID: 84869992760     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.111.263830     Document Type: Article

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