An update on primary hip osteoarthritis including altered wnt and TGF-β associated gene expression from the bony component of the disease

Rheumatology

Volumn 50, Issue 12, 2011, Pages 2166-2175

  Kumarasinghe, Duminda D ^a,b   Hopwood, Blair ^a   Kuliwaba, Julia S ^a,b   Atkins, Gerald J ^b   Fazzalari, Nicola L ^a,b  

^a Bone and Joint Research Laboratory   (Australia)

^b UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

Gene; Hip osteoarthritis; Osteoblast; TGF signalling; Trabecular bone; Wingless MMTV integration (Wnt)

Indexed keywords

ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; ACTIVIN RECEPTOR 1; AROMATASE; BETA CATENIN; BONE MORPHOGENETIC PROTEIN 5; CATHEPSIN K; ENDOGLIN; FOLLISTATIN; GELATINASE B; HISTONE DEACETYLASE 4; INHIBIN A; INTERLEUKIN 6; KRUPPEL LIKE FACTOR; KRUPPEL LIKE FACTOR 10; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 5; MESSENGER RNA; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; SCLEROSTIN; SMAD3 PROTEIN; SMAD4 PROTEIN; SOMATOMEDIN B; SOMATOMEDIN C; TRANSCRIPTION FACTOR JUNB; TRANSCRIPTION FACTOR RUNX2; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; WNT PROTEIN;

AGING; BONE DEVELOPMENT; BONE MASS; BONE MATRIX; BONE REMODELING; BONE STRUCTURE; BONE TURNOVER; CHEMOTAXIS; DISEASE ASSOCIATION; FRACTURE; FUNCTIONAL GENOMICS; GENE EXPRESSION; GENETIC PREDISPOSITION; GRANULOCYTE; HIP OSTEOARTHRITIS; HUMAN; INFLAMMATORY CELL; JOINT LAXITY; MONOCYTE; OBESITY; OSTEOBLAST; PATHOGENESIS; PRIMARY OSTEOPOROSIS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN SECRETION; REVIEW; SEX DIFFERENCE; SIGNAL TRANSDUCTION;

ANIMALS; BIOLOGICAL MARKERS; BONE REMODELING; CELL PROLIFERATION; GENE EXPRESSION; HIP FRACTURES; HUMANS; MICE; OSTEOARTHRITIS, HIP; OSTEOBLASTS; RATS; RISK FACTORS; SIGNAL TRANSDUCTION; SPINAL FRACTURES; TRANSFORMING GROWTH FACTOR BETA; WNT PROTEINS;

EID: 82355191817     PISSN: 14620324     EISSN: 14620332     Source Type: Journal    
DOI: 10.1093/rheumatology/ker291     Document Type: Review

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