MiR-29b as a therapeutic agent for angiotensin ii-induced cardiac fibrosis by targeting TGF-β/Smad3 signaling

Molecular Therapy

Volumn 22, Issue 5, 2014, Pages 974-985

  Zhang, Yang ^a   Huang, Xiao Ru ^a   Wei, Li Hua ^a   Chung, Arthur Ck ^a   Yu, Cheuk Man ^a   Lan, Hui Yao ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; MICRORNA 29A; MICRORNA 29B; MICRORNA 29C; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; ANGIOTENSIN II; MIRN29 MICRORNA, HUMAN; SMAD3 PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; DRUG TARGETING; FEMALE; FIBROBLAST CULTURE; GENE TRANSFER; HEART MUSCLE CELL; HEART MUSCLE FIBROSIS; HYPERTENSION; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CHEMICALLY INDUCED; DISEASE MODEL; ENDOMYOCARDIAL FIBROSIS; GENE EXPRESSION REGULATION; GENE SILENCING; GENETICS; HUMAN; METABOLISM; MOLECULARLY TARGETED THERAPY; TOXICITY;

ANGIOTENSIN II; ANIMALS; DISEASE MODELS, ANIMAL; ENDOMYOCARDIAL FIBROSIS; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; HUMANS; HYPERTENSION; MICE; MICRORNAS; MOLECULAR TARGETED THERAPY; SIGNAL TRANSDUCTION; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

EID: 84899982846     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2014.25     Document Type: Article

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