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Volumn 200, Issue 1-2, 2011, Pages 77-87

Global gene expression profiles of MT knockout and wild-type mice in the condition of doxorubicin-induced cardiomyopathy

Author keywords

Cardiotoxicity; Doxorubicin; Gene expression profile; Knockout mice; Metallothionein; Microarray

Indexed keywords

DOXORUBICIN; JANUS KINASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PROTEIN P53; STAT PROTEIN; WNT PROTEIN;

EID: 78650169897     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2010.10.017     Document Type: Article
Times cited : (28)

References (46)
  • 1
    • 0037200841 scopus 로고    scopus 로고
    • Induction of metallothionein by zinc protects from daunorubicin toxicity in rats
    • Ali M.M., Frei E., Straub J., Breuer A., Wiessler M. Induction of metallothionein by zinc protects from daunorubicin toxicity in rats. Toxicology 2002, 179:85-93.
    • (2002) Toxicology , vol.179 , pp. 85-93
    • Ali, M.M.1    Frei, E.2    Straub, J.3    Breuer, A.4    Wiessler, M.5
  • 3
    • 0019957727 scopus 로고
    • Immunohistochemical localization of metallothionein in cell nucleus and cytoplasm of rat liver and kidney
    • Banerjee D., Onosaka S., Cherian M.G. Immunohistochemical localization of metallothionein in cell nucleus and cytoplasm of rat liver and kidney. Toxicology 1982, 24:95-105.
    • (1982) Toxicology , vol.24 , pp. 95-105
    • Banerjee, D.1    Onosaka, S.2    Cherian, M.G.3
  • 8
    • 34249814024 scopus 로고    scopus 로고
    • WNTS and WNT receptors as therapeutic tools and targets in human disease processes
    • Chien A.J., Moon R.T. WNTS and WNT receptors as therapeutic tools and targets in human disease processes. Front. Biosci. 2007, 12:448-457.
    • (2007) Front. Biosci. , vol.12 , pp. 448-457
    • Chien, A.J.1    Moon, R.T.2
  • 10
    • 0022967083 scopus 로고
    • Redox cycling of anthracyclines by cardiac mitochondria. I. Anthracycline radical formation by NADH dehydrogenase
    • Davies K.J., Doroshow J.H. Redox cycling of anthracyclines by cardiac mitochondria. I. Anthracycline radical formation by NADH dehydrogenase. J. Biol. Chem. 1986, 261:3060-3067.
    • (1986) J. Biol. Chem. , vol.261 , pp. 3060-3067
    • Davies, K.J.1    Doroshow, J.H.2
  • 11
    • 0023028913 scopus 로고
    • Redox cycling of anthracyclines by cardiac mitochondria. II. Formation of superoxide anion, hydrogen peroxide, and hydroxyl radical
    • Doroshow J.H., Davies K.J. Redox cycling of anthracyclines by cardiac mitochondria. II. Formation of superoxide anion, hydrogen peroxide, and hydroxyl radical. J. Biol. Chem. 1986, 261:3068-3074.
    • (1986) J. Biol. Chem. , vol.261 , pp. 3068-3074
    • Doroshow, J.H.1    Davies, K.J.2
  • 12
    • 34948890043 scopus 로고    scopus 로고
    • Mitochondrial uncoupling proteins-what is their physiological role?
    • Echtay K.S. Mitochondrial uncoupling proteins-what is their physiological role?. Free Radic. Biol. Med. 2007, 43:1351-1371.
    • (2007) Free Radic. Biol. Med. , vol.43 , pp. 1351-1371
    • Echtay, K.S.1
  • 15
    • 0035797151 scopus 로고    scopus 로고
    • Mitochondria as subcellular targets for clinically useful anthracyclines
    • Jung K., Reszka R. Mitochondria as subcellular targets for clinically useful anthracyclines. Adv. Drug Deliv. Rev. 2001, 49:87-105.
    • (2001) Adv. Drug Deliv. Rev. , vol.49 , pp. 87-105
    • Jung, K.1    Reszka, R.2
  • 16
    • 0030803635 scopus 로고    scopus 로고
    • Overexpression of metallothionein in the heart of transgenic mice suppresses doxorubicin cardiotoxicity
    • Kang Y.J., Chen Y., Yu A., Voss-McCowan M., Epstein P.N. Overexpression of metallothionein in the heart of transgenic mice suppresses doxorubicin cardiotoxicity. J. Clin. Invest. 1997, 100:1501-1506.
    • (1997) J. Clin. Invest. , vol.100 , pp. 1501-1506
    • Kang, Y.J.1    Chen, Y.2    Yu, A.3    Voss-McCowan, M.4    Epstein, P.N.5
  • 17
    • 0034608083 scopus 로고    scopus 로고
    • Suppression by metallothionein of doxorubicin-induced cardiomyocyte apoptosis through inhibition of p38 mitogen-activated protein kinases
    • Kang Y.J., Zhou Z.X., Wang G.W., Buridi A., Klein J.B. Suppression by metallothionein of doxorubicin-induced cardiomyocyte apoptosis through inhibition of p38 mitogen-activated protein kinases. J. Biol. Chem. 2000, 275:13690-13698.
    • (2000) J. Biol. Chem. , vol.275 , pp. 13690-13698
    • Kang, Y.J.1    Zhou, Z.X.2    Wang, G.W.3    Buridi, A.4    Klein, J.B.5
  • 20
    • 0027137181 scopus 로고
    • The ultrastructural localization of metallothionein in cadmium exposed rat liver
    • Leyshon-Sorland K., Stang E. The ultrastructural localization of metallothionein in cadmium exposed rat liver. Histochem. J. 1993, 25:857-864.
    • (1993) Histochem. J. , vol.25 , pp. 857-864
    • Leyshon-Sorland, K.1    Stang, E.2
  • 21
    • 25844519056 scopus 로고    scopus 로고
    • Uncoupling proteins 2 and 3 function in concert to augment tolerance to cardiac ischemia
    • McLeod C.J., Aziz A., Hoyt R.F., McCoy J.P., Sack M.N. Uncoupling proteins 2 and 3 function in concert to augment tolerance to cardiac ischemia. J. Biol. Chem. 2005, 280:33470-33476.
    • (2005) J. Biol. Chem. , vol.280 , pp. 33470-33476
    • McLeod, C.J.1    Aziz, A.2    Hoyt, R.F.3    McCoy, J.P.4    Sack, M.N.5
  • 22
    • 27744494443 scopus 로고    scopus 로고
    • Modulation of cytochrome C oxidase-va is possibly involved in metallothionein protection from doxorubicin cardiotoxicity
    • Merten K.E., Feng W., Zhang L., Pierce W., Cai J., Klein J.B., Kang Y.J. Modulation of cytochrome C oxidase-va is possibly involved in metallothionein protection from doxorubicin cardiotoxicity. J. Pharmacol. Exp. Ther. 2005, 315:1314-1319.
    • (2005) J. Pharmacol. Exp. Ther. , vol.315 , pp. 1314-1319
    • Merten, K.E.1    Feng, W.2    Zhang, L.3    Pierce, W.4    Cai, J.5    Klein, J.B.6    Kang, Y.J.7
  • 23
    • 78650168991 scopus 로고    scopus 로고
    • Cardiotoxicity of antitumor drugs
    • Minotti G. Cardiotoxicity of antitumor drugs. Toxicol.Lett. 2007, 172:S5-S15.
    • (2007) Toxicol.Lett. , vol.172
    • Minotti, G.1
  • 24
    • 20444403004 scopus 로고    scopus 로고
    • Gene expression profiles in the liver and kidney of metallothionein-null mice
    • Miura N., Koizumi S. Gene expression profiles in the liver and kidney of metallothionein-null mice. Biochem. Biophys. Res. Commun. 2005, 332:949-955.
    • (2005) Biochem. Biophys. Res. Commun. , vol.332 , pp. 949-955
    • Miura, N.1    Koizumi, S.2
  • 25
    • 0034683101 scopus 로고    scopus 로고
    • Metallothionein mediates gene expression of 3.1 mRNA (PTZ17) related to epileptic seizure
    • Miura N., Naganuma A. Metallothionein mediates gene expression of 3.1 mRNA (PTZ17) related to epileptic seizure. FEBS Lett. 2000, 479:146-148.
    • (2000) FEBS Lett. , vol.479 , pp. 146-148
    • Miura, N.1    Naganuma, A.2
  • 27
    • 0031816594 scopus 로고    scopus 로고
    • Immunohistochemical detection of metallothionein in liver, duodenum and kidney after dietary copper-overload in rats
    • Mullins J.E., Fuentealba I.C. Immunohistochemical detection of metallothionein in liver, duodenum and kidney after dietary copper-overload in rats. Histol. Histopathol. 1998, 13:627-633.
    • (1998) Histol. Histopathol. , vol.13 , pp. 627-633
    • Mullins, J.E.1    Fuentealba, I.C.2
  • 28
    • 33646246774 scopus 로고    scopus 로고
    • Different mechanisms of mitochondrial proton leak in ischaemia/reperfusion injury and preconditioning: implications for pathology and cardioprotection
    • Nadtochiy S.M., Tompkins A.J., Brookes P.S. Different mechanisms of mitochondrial proton leak in ischaemia/reperfusion injury and preconditioning: implications for pathology and cardioprotection. Biochem. J. 2006, 395:611-618.
    • (2006) Biochem. J. , vol.395 , pp. 611-618
    • Nadtochiy, S.M.1    Tompkins, A.J.2    Brookes, P.S.3
  • 29
    • 27144443115 scopus 로고    scopus 로고
    • Doxorubicin cardiac dysfunction: effects on calcium regulatory proteins, sarcoplasmic reticulum, and triiodothyronine
    • Olson R.D., Gambliel H.A., Vestal R.E., Shadle S.E., Charlier H.A., Cusack B.J. Doxorubicin cardiac dysfunction: effects on calcium regulatory proteins, sarcoplasmic reticulum, and triiodothyronine. Cardiovasc. Toxicol. 2005, 5:269-283.
    • (2005) Cardiovasc. Toxicol. , vol.5 , pp. 269-283
    • Olson, R.D.1    Gambliel, H.A.2    Vestal, R.E.3    Shadle, S.E.4    Charlier, H.A.5    Cusack, B.J.6
  • 30
    • 0025051505 scopus 로고
    • Doxorubicin cardiotoxicity: analysis of prevailing hypotheses
    • Olson R.D., Mushlin P.S. Doxorubicin cardiotoxicity: analysis of prevailing hypotheses. FASEB J. 1990, 4:3076-3086.
    • (1990) FASEB J. , vol.4 , pp. 3076-3086
    • Olson, R.D.1    Mushlin, P.S.2
  • 31
    • 0024236167 scopus 로고
    • Involvement of cardiac metallothionein in prevention of adriamycin induced lipid peroxidation in the heart
    • Satoh M., Naganuma A., Imura N. Involvement of cardiac metallothionein in prevention of adriamycin induced lipid peroxidation in the heart. Toxicology 1988, 53:231-237.
    • (1988) Toxicology , vol.53 , pp. 231-237
    • Satoh, M.1    Naganuma, A.2    Imura, N.3
  • 32
    • 0034705510 scopus 로고    scopus 로고
    • Modulation of adriamycin toxicity by tissue-specific induction of metallothionein synthesis in mice
    • Satoh M., Naganuma A., Imura N. Modulation of adriamycin toxicity by tissue-specific induction of metallothionein synthesis in mice. Life Sci. 2000, 67:627-634.
    • (2000) Life Sci. , vol.67 , pp. 627-634
    • Satoh, M.1    Naganuma, A.2    Imura, N.3
  • 33
    • 34047121135 scopus 로고    scopus 로고
    • Metallothionein protects against doxorubicin-induced cardiomyopathy through inhibition of superoxide generation and related nitrosative impairment
    • Shuai Y., Guo J.-B., Peng S.-Q., Zhang L.-S., Guo J., Han G., Dong Y.-S. Metallothionein protects against doxorubicin-induced cardiomyopathy through inhibition of superoxide generation and related nitrosative impairment. Toxicol. Lett. 2007, 170:66-74.
    • (2007) Toxicol. Lett. , vol.170 , pp. 66-74
    • Shuai, Y.1    Guo, J.-B.2    Peng, S.-Q.3    Zhang, L.-S.4    Guo, J.5    Han, G.6    Dong, Y.-S.7
  • 34
    • 66949171305 scopus 로고    scopus 로고
    • Anthracycline-induced cardiotoxicity: overview of studies examining the roles of oxidative stress and free cellular iron
    • Simunek T., Sterba M., Popelova O., Adamcova M., Hrdina R., Gersl V. Anthracycline-induced cardiotoxicity: overview of studies examining the roles of oxidative stress and free cellular iron. Pharmacol. Rep. 2009, 61:154-171.
    • (2009) Pharmacol. Rep. , vol.61 , pp. 154-171
    • Simunek, T.1    Sterba, M.2    Popelova, O.3    Adamcova, M.4    Hrdina, R.5    Gersl, V.6
  • 35
    • 0035870265 scopus 로고    scopus 로고
    • Attenuation of doxorubicin chronic toxicity in metallothionein-overexpressing transgenic mouse heart
    • Sun X., Zhou Z., Kang Y.J. Attenuation of doxorubicin chronic toxicity in metallothionein-overexpressing transgenic mouse heart. Cancer Res. 2001, 61:3382-3387.
    • (2001) Cancer Res. , vol.61 , pp. 3382-3387
    • Sun, X.1    Zhou, Z.2    Kang, Y.J.3
  • 36
    • 33847096349 scopus 로고    scopus 로고
    • Doxorubicin-induced cardiomyopathy from the cardiotoxic mechanisms to management
    • Takemura G., Fujiwara H. Doxorubicin-induced cardiomyopathy from the cardiotoxic mechanisms to management. Prog. Cardiovasc. Dis. 2007, 49:330-352.
    • (2007) Prog. Cardiovasc. Dis. , vol.49 , pp. 330-352
    • Takemura, G.1    Fujiwara, H.2
  • 38
    • 43049117151 scopus 로고    scopus 로고
    • The Wnt/frizzled pathway in cardiovascular development and disease: friend or foe?
    • van de Schans V.A.M., Smits J.F.M., Blankesteijn W.M. The Wnt/frizzled pathway in cardiovascular development and disease: friend or foe?. Eur. J. Pharmacol. 2008, 585:338-345.
    • (2008) Eur. J. Pharmacol. , vol.585 , pp. 338-345
    • van de Schans, V.A.M.1    Smits, J.F.M.2    Blankesteijn, W.M.3
  • 40
    • 0033054346 scopus 로고    scopus 로고
    • Inhibition of doxorubicin toxicity in cultured neonatal mouse cardiomyocytes with elevated metallothionein levels
    • Wang G.W., Kang Y.J. Inhibition of doxorubicin toxicity in cultured neonatal mouse cardiomyocytes with elevated metallothionein levels. J. Pharmacol. Exp. Ther. 1999, 288:938-944.
    • (1999) J. Pharmacol. Exp. Ther. , vol.288 , pp. 938-944
    • Wang, G.W.1    Kang, Y.J.2
  • 41
    • 0034913884 scopus 로고    scopus 로고
    • Metallothionein inhibits doxorubicin-induced mitochondrial cytochrome c release and caspase-3 activation in cardiomyocytes
    • Wang G.W., Klein J.B., Kang Y.J. Metallothionein inhibits doxorubicin-induced mitochondrial cytochrome c release and caspase-3 activation in cardiomyocytes. J. Pharmacol. Exp. Ther. 2001, 298:461-468.
    • (2001) J. Pharmacol. Exp. Ther. , vol.298 , pp. 461-468
    • Wang, G.W.1    Klein, J.B.2    Kang, Y.J.3
  • 42
    • 34548695952 scopus 로고    scopus 로고
    • Mitogen-activated protein kinases in heart development and diseases
    • Wang Y. Mitogen-activated protein kinases in heart development and diseases. Circulation 2007, 116:1413-1423.
    • (2007) Circulation , vol.116 , pp. 1413-1423
    • Wang, Y.1
  • 43
    • 0035956862 scopus 로고    scopus 로고
    • Zinc metallothionein imported into liver mitochondria modulates respiration
    • Ye B., Maret W., Vallee B.L. Zinc metallothionein imported into liver mitochondria modulates respiration. Proc. Natl. Acad. Sci. U.S.A. 2001, 98:2317-2322.
    • (2001) Proc. Natl. Acad. Sci. U.S.A. , vol.98 , pp. 2317-2322
    • Ye, B.1    Maret, W.2    Vallee, B.L.3
  • 45
    • 0033838708 scopus 로고    scopus 로고
    • Immunocytochemical localization of metallothionein and its relation to doxorubicin toxicity in transgenic mouse heart
    • Zhou Z., Kang Y.J. Immunocytochemical localization of metallothionein and its relation to doxorubicin toxicity in transgenic mouse heart. Am. J. Pathol. 2000, 156:1653-1662.
    • (2000) Am. J. Pathol. , vol.156 , pp. 1653-1662
    • Zhou, Z.1    Kang, Y.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.