메뉴 건너뛰기




Volumn 53, Issue 2, 2016, Pages 1092-1107

Transcriptional Regulation of Brain-Derived Neurotrophic Factor (BDNF) by Methyl CpG Binding Protein 2 (MeCP2): a Novel Mechanism for Re-Myelination and/or Myelin Repair Involved in the Treatment of Multiple Sclerosis (MS)

Author keywords

Autoimmune disease; Brain derived neurotrophic factor (BDNF); Epigenetics; Experimental autoimmune encephalomyelitis (EAE); Histone deacetylase (HDAC) inhibitors; Methyl CpG binding protein 2 (MeCP2); Multiple sclerosis (MS)

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; ENZYME INHIBITOR; HISTONE DEACETYLASE INHIBITOR; LYSINE ACETYLTRANSFERASE INHIBITOR; METHYL CPG BINDING PROTEIN 2; MYELIN; UNCLASSIFIED DRUG;

EID: 84958161142     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-014-9074-1     Document Type: Review
Times cited : (55)

References (211)
  • 1
    • 0141846521 scopus 로고    scopus 로고
    • Impact of recently diagnosed multiple sclerosis on quality of life, anxiety, depression and distress of patients and partners
    • PID: 14616290
    • Janssens AC, van Doorn PA, de Boer JB, van der Meche FG, Passchier J, Hintzen RQ (2003) Impact of recently diagnosed multiple sclerosis on quality of life, anxiety, depression and distress of patients and partners. Acta Neurol Scand 108(6):389–395
    • (2003) Acta Neurol Scand , vol.108 , Issue.6 , pp. 389-395
    • Janssens, A.C.1    van Doorn, P.A.2    de Boer, J.B.3    van der Meche, F.G.4    Passchier, J.5    Hintzen, R.Q.6
  • 2
    • 83455187948 scopus 로고    scopus 로고
    • Multiple sclerosis: more pieces of the immunological puzzle
    • PID: 22172612
    • Gold R, Montalban X (2012) Multiple sclerosis: more pieces of the immunological puzzle. Lancet Neurol 11(1):9–10
    • (2012) Lancet Neurol , vol.11 , Issue.1 , pp. 9-10
    • Gold, R.1    Montalban, X.2
  • 4
    • 77955844059 scopus 로고    scopus 로고
    • Emerging concepts in autoimmune encephalomyelitis beyond the CD4/T(H)1 paradigm
    • Batoulis H, Addicks K, Kuerten S (2010) Emerging concepts in autoimmune encephalomyelitis beyond the CD4/T(H)1 paradigm. Ann Anat Ana Anz Off Organ Anat Ges 192(4):179–193
    • (2010) Ann Anat Ana Anz Off Organ Anat Ges , vol.192 , Issue.4 , pp. 179-193
    • Batoulis, H.1    Addicks, K.2    Kuerten, S.3
  • 5
    • 77956898047 scopus 로고    scopus 로고
    • Immunological basis for the development of tissue inflammation and organ-specific autoimmunity in animal models of multiple sclerosis
    • PID: 19513635
    • Korn T, Mitsdoerffer M, Kuchroo VK (2010) Immunological basis for the development of tissue inflammation and organ-specific autoimmunity in animal models of multiple sclerosis. Results Probl Cell Differ 51:43–74
    • (2010) Results Probl Cell Differ , vol.51 , pp. 43-74
    • Korn, T.1    Mitsdoerffer, M.2    Kuchroo, V.K.3
  • 6
    • 0026733704 scopus 로고
    • Proinflammatory and antiinflammatory cytokines in multiple sclerosis and central nervous system acquired immunodeficiency syndrome
    • PID: 1445805
    • Merrill JE (1992) Proinflammatory and antiinflammatory cytokines in multiple sclerosis and central nervous system acquired immunodeficiency syndrome. J Immunother 1991 12(3):167–170
    • (1992) J Immunother 1991 , vol.12 , Issue.3 , pp. 167-170
    • Merrill, J.E.1
  • 7
    • 0034633711 scopus 로고    scopus 로고
    • Fas(t) track to apoptosis in MS: TNF receptors may suppress or potentiate CNS demyelination
    • PID: 11061241
    • Segal BM, Cross AH (2000) Fas(t) track to apoptosis in MS: TNF receptors may suppress or potentiate CNS demyelination. Neurology 55(7):906–907
    • (2000) Neurology , vol.55 , Issue.7 , pp. 906-907
    • Segal, B.M.1    Cross, A.H.2
  • 8
    • 37549070224 scopus 로고    scopus 로고
    • Normal-appearing white matter in multiple sclerosis is in a subtle balance between inflammation and neuroprotection
    • PID: 18056737
    • Zeis T, Graumann U, Reynolds R, Schaeren-Wiemers N (2008) Normal-appearing white matter in multiple sclerosis is in a subtle balance between inflammation and neuroprotection. Brain 131(1):288–303
    • (2008) Brain , vol.131 , Issue.1 , pp. 288-303
    • Zeis, T.1    Graumann, U.2    Reynolds, R.3    Schaeren-Wiemers, N.4
  • 9
    • 33749059726 scopus 로고    scopus 로고
    • The neurobiology of multiple sclerosis: genes, inflammation, and neurodegeneration
    • PID: 17015227
    • Hauser SL, Oksenberg JR (2006) The neurobiology of multiple sclerosis: genes, inflammation, and neurodegeneration. Neuron 52(1):61–76
    • (2006) Neuron , vol.52 , Issue.1 , pp. 61-76
    • Hauser, S.L.1    Oksenberg, J.R.2
  • 10
    • 72449136385 scopus 로고    scopus 로고
    • Experimental autoimmune encephalomyelitis-induced upregulation of tumor necrosis factor-alpha in the dorsal root ganglia
    • PID: 19667008
    • Melanson M, Miao P, Eisenstat D, Gong Y, Gu X, Au K et al (2009) Experimental autoimmune encephalomyelitis-induced upregulation of tumor necrosis factor-alpha in the dorsal root ganglia. Mult Scler 15(10):1135–1145
    • (2009) Mult Scler , vol.15 , Issue.10 , pp. 1135-1145
    • Melanson, M.1    Miao, P.2    Eisenstat, D.3    Gong, Y.4    Gu, X.5    Au, K.6
  • 11
    • 77951951889 scopus 로고    scopus 로고
    • Cytokine networks in multiple sclerosis: lost in translation
    • PID: 20442570
    • Codarri L, Fontana A, Becher B (2010) Cytokine networks in multiple sclerosis: lost in translation. Curr Opin Neurol 23(3):205–211
    • (2010) Curr Opin Neurol , vol.23 , Issue.3 , pp. 205-211
    • Codarri, L.1    Fontana, A.2    Becher, B.3
  • 12
    • 12344306108 scopus 로고    scopus 로고
    • Treatment with soluble tumor necrosis factor receptor (sTNFR):Fc/p80 fusion protein ameliorates relapsing-remitting experimental autoimmune encephalomyelitis and decreases chemokine expression
    • PID: 15621573
    • Glabinski AR, Bielecki B, Kawczak JA, Tuohy VK, Selmaj K, Ransohoff RM (2004) Treatment with soluble tumor necrosis factor receptor (sTNFR):Fc/p80 fusion protein ameliorates relapsing-remitting experimental autoimmune encephalomyelitis and decreases chemokine expression. Autoimmunity 37(6–7):465–471
    • (2004) Autoimmunity , vol.37 , Issue.6-7 , pp. 465-471
    • Glabinski, A.R.1    Bielecki, B.2    Kawczak, J.A.3    Tuohy, V.K.4    Selmaj, K.5    Ransohoff, R.M.6
  • 13
    • 36148940060 scopus 로고    scopus 로고
    • Treatment for ataxia in multiple sclerosis. The Cochrane database of systematic reviews
    • Mills RJ, Yap L, Young CA (2007) Treatment for ataxia in multiple sclerosis. The Cochrane database of systematic reviews. (1):CD005029
    • (2007) (1):CD005029
    • Mills, R.J.1    Yap, L.2    Young, C.A.3
  • 15
    • 0346733218 scopus 로고    scopus 로고
    • Treatments for spasticity and pain in multiple sclerosis: a systematic review
    • Beard S, Hunn A, Wight J (2003) Treatments for spasticity and pain in multiple sclerosis: a systematic review. Health Technol Assess 7(40):iii, ix-x, 1–111
    • (2003) Health Technol Assess 7(40):iii, ix-x , pp. 1-111
    • Beard, S.1    Hunn, A.2    Wight, J.3
  • 16
    • 77958134750 scopus 로고    scopus 로고
    • Fatigue and cognition in patients with relapsing multiple sclerosis treated with interferon beta
    • PID: 20942577
    • Melanson M, Grossberndt A, Klowak M, Leong C, Frost EE, Prout M et al (2010) Fatigue and cognition in patients with relapsing multiple sclerosis treated with interferon beta. Int J Neurosci 120(10):631–640
    • (2010) Int J Neurosci , vol.120 , Issue.10 , pp. 631-640
    • Melanson, M.1    Grossberndt, A.2    Klowak, M.3    Leong, C.4    Frost, E.E.5    Prout, M.6
  • 17
    • 84897574115 scopus 로고    scopus 로고
    • Multiple sclerosis: current and emerging disease-modifying therapies and treatment strategies
    • PID: 24485135
    • Wingerchuk DM, Carter JL (2014) Multiple sclerosis: current and emerging disease-modifying therapies and treatment strategies. Mayo Clin Proc 89(2):225–240
    • (2014) Mayo Clin Proc , vol.89 , Issue.2 , pp. 225-240
    • Wingerchuk, D.M.1    Carter, J.L.2
  • 18
    • 55349135951 scopus 로고    scopus 로고
    • Novel therapeutic strategies for multiple sclerosis–a multifaceted adversary
    • PID: 18974749
    • Lopez-Diego RS, Weiner HL (2008) Novel therapeutic strategies for multiple sclerosis–a multifaceted adversary. Nat Rev Drug Discov 7(11):909–925
    • (2008) Nat Rev Drug Discov , vol.7 , Issue.11 , pp. 909-925
    • Lopez-Diego, R.S.1    Weiner, H.L.2
  • 19
    • 77949412549 scopus 로고    scopus 로고
    • Current and future disease-modifying therapies in multiple sclerosis
    • PID: 20456216
    • Lim SY, Constantinescu CS (2010) Current and future disease-modifying therapies in multiple sclerosis. Int J Clin Pract 64(5):637–650
    • (2010) Int J Clin Pract , vol.64 , Issue.5 , pp. 637-650
    • Lim, S.Y.1    Constantinescu, C.S.2
  • 20
    • 84885589335 scopus 로고    scopus 로고
    • Review of the novelties presented at the 28th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) (III)
    • PID: 24052443
    • Fernandez O, Arnal-Garcia C, Arroyo-Gonzalez R, Brieva L, Calles-Hernandez MC, Casanova-Estruch B et al (2013) Review of the novelties presented at the 28th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) (III). Rev Neurol 57(7):317–329
    • (2013) Rev Neurol , vol.57 , Issue.7 , pp. 317-329
    • Fernandez, O.1    Arnal-Garcia, C.2    Arroyo-Gonzalez, R.3    Brieva, L.4    Calles-Hernandez, M.C.5    Casanova-Estruch, B.6
  • 22
    • 84857769209 scopus 로고    scopus 로고
    • Multiple sclerosis - remyelination failure as a cause of disease progression
    • PID: 22237705
    • Hagemeier K, Bruck W, Kuhlmann T (2012) Multiple sclerosis - remyelination failure as a cause of disease progression. Histol Histopathol 27(3):277–287
    • (2012) Histol Histopathol , vol.27 , Issue.3 , pp. 277-287
    • Hagemeier, K.1    Bruck, W.2    Kuhlmann, T.3
  • 23
    • 79952534189 scopus 로고    scopus 로고
    • Regulation of chromatin by histone modifications
    • PID: 21321607
    • Bannister AJ, Kouzarides T (2011) Regulation of chromatin by histone modifications. Cell Res 21(3):381–395
    • (2011) Cell Res , vol.21 , Issue.3 , pp. 381-395
    • Bannister, A.J.1    Kouzarides, T.2
  • 24
    • 80051684615 scopus 로고    scopus 로고
    • Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis
    • PID: 21833088
    • Sawcer S, Hellenthal G, Pirinen M, Spencer CC, Patsopoulos NA, Moutsianas L et al (2011) Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature 476(7359):214–219
    • (2011) Nature , vol.476 , Issue.7359 , pp. 214-219
    • Sawcer, S.1    Hellenthal, G.2    Pirinen, M.3    Spencer, C.C.4    Patsopoulos, N.A.5    Moutsianas, L.6
  • 25
    • 41549100059 scopus 로고    scopus 로고
    • Therapeutic potential of vitamin D for multiple sclerosis
    • PID: 18289005
    • Niino M, Fukazawa T, Kikuchi S, Sasaki H (2008) Therapeutic potential of vitamin D for multiple sclerosis. Curr Med Chem 15(5):499–505
    • (2008) Curr Med Chem , vol.15 , Issue.5 , pp. 499-505
    • Niino, M.1    Fukazawa, T.2    Kikuchi, S.3    Sasaki, H.4
  • 26
    • 84874631683 scopus 로고    scopus 로고
    • Epstein-Barr virus and multiple sclerosis: association or causation?
    • PID: 23448218
    • Pakpoor J, Giovannoni G, Ramagopalan SV (2013) Epstein-Barr virus and multiple sclerosis: association or causation? Expert Rev Neurother 13(3):287–297
    • (2013) Expert Rev Neurother , vol.13 , Issue.3 , pp. 287-297
    • Pakpoor, J.1    Giovannoni, G.2    Ramagopalan, S.V.3
  • 27
    • 18944374967 scopus 로고    scopus 로고
    • Epidemiology and etiology of multiple sclerosis
    • PID: 15893675
    • Kurtzke JF (2005) Epidemiology and etiology of multiple sclerosis. Phys Med Rehabil Clin N Am 16(2):327–349
    • (2005) Phys Med Rehabil Clin N Am , vol.16 , Issue.2 , pp. 327-349
    • Kurtzke, J.F.1
  • 28
    • 84871922920 scopus 로고    scopus 로고
    • Epigenetic changes in patients with multiple sclerosis
    • PID: 23165337
    • Koch MW, Metz LM, Kovalchuk O (2013) Epigenetic changes in patients with multiple sclerosis. Nat Rev Neurol 9(1):35–43
    • (2013) Nat Rev Neurol , vol.9 , Issue.1 , pp. 35-43
    • Koch, M.W.1    Metz, L.M.2    Kovalchuk, O.3
  • 29
    • 84934442123 scopus 로고    scopus 로고
    • Epigenetic biomarker to determine replicative senescence of cultured cells
    • PID: 23929112
    • Koch CM, Wagner W (2013) Epigenetic biomarker to determine replicative senescence of cultured cells. Methods Mol Biol 1048:309–321
    • (2013) Methods Mol Biol , vol.1048 , pp. 309-321
    • Koch, C.M.1    Wagner, W.2
  • 30
    • 77953394241 scopus 로고    scopus 로고
    • Multiple sclerosis: risk factors, prodromes, and potential causal pathways
    • PID: 20610348
    • Ramagopalan SV, Dobson R, Meier UC, Giovannoni G (2010) Multiple sclerosis: risk factors, prodromes, and potential causal pathways. Lancet Neurol 9(7):727–739
    • (2010) Lancet Neurol , vol.9 , Issue.7 , pp. 727-739
    • Ramagopalan, S.V.1    Dobson, R.2    Meier, U.C.3    Giovannoni, G.4
  • 31
    • 79958247819 scopus 로고    scopus 로고
    • Epigenetic dysregulation of epstein-barr virus latency and development of autoimmune disease
    • PID: 21627044
    • Niller HH, Wolf H, Ay E, Minarovits J (2011) Epigenetic dysregulation of epstein-barr virus latency and development of autoimmune disease. Adv Exp Med Biol 711:82–102
    • (2011) Adv Exp Med Biol , vol.711 , pp. 82-102
    • Niller, H.H.1    Wolf, H.2    Ay, E.3    Minarovits, J.4
  • 33
    • 79959536193 scopus 로고    scopus 로고
    • CD44 Reciprocally regulates the differentiation of encephalitogenic Th1/Th17 and Th2/regulatory T cells through epigenetic modulation involving DNA methylation of cytokine gene promoters, thereby controlling the development of experimental autoimmune encephalomyelitis
    • PID: 21551360
    • Guan H, Nagarkatti PS, Nagarkatti M (2011) CD44 Reciprocally regulates the differentiation of encephalitogenic Th1/Th17 and Th2/regulatory T cells through epigenetic modulation involving DNA methylation of cytokine gene promoters, thereby controlling the development of experimental autoimmune encephalomyelitis. J Immunol 186(12):6955–6964
    • (2011) J Immunol , vol.186 , Issue.12 , pp. 6955-6964
    • Guan, H.1    Nagarkatti, P.S.2    Nagarkatti, M.3
  • 34
    • 80052859027 scopus 로고    scopus 로고
    • Critical role of TCF-1 in repression of the IL-17 gene
    • PID: 21935461
    • Ma J, Wang R, Fang X, Ding Y, Sun Z (2011) Critical role of TCF-1 in repression of the IL-17 gene. PLoS One 6(9):e24768
    • (2011) PLoS One , vol.6 , Issue.9 , pp. e24768
    • Ma, J.1    Wang, R.2    Fang, X.3    Ding, Y.4    Sun, Z.5
  • 35
    • 0024342686 scopus 로고
    • Identification of a mammalian protein that binds specifically to DNA containing methylated CpGs
    • PID: 2758464
    • Meehan RR, Lewis JD, McKay S, Kleiner EL, Bird AP (1989) Identification of a mammalian protein that binds specifically to DNA containing methylated CpGs. Cell 58(3):499–507
    • (1989) Cell , vol.58 , Issue.3 , pp. 499-507
    • Meehan, R.R.1    Lewis, J.D.2    McKay, S.3    Kleiner, E.L.4    Bird, A.P.5
  • 36
    • 0026747761 scopus 로고
    • Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA
    • PID: 1606614
    • Lewis JD, Meehan RR, Henzel WJ, Maurer-Fogy I, Jeppesen P, Klein F et al (1992) Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA. Cell 69(6):905–914
    • (1992) Cell , vol.69 , Issue.6 , pp. 905-914
    • Lewis, J.D.1    Meehan, R.R.2    Henzel, W.J.3    Maurer-Fogy, I.4    Jeppesen, P.5    Klein, F.6
  • 37
    • 12144287057 scopus 로고    scopus 로고
    • A previously unidentified MECP2 open reading frame defines a new protein isoform relevant to Rett syndrome
    • PID: 15034579
    • Mnatzakanian GN, Lohi H, Munteanu I, Alfred SE, Yamada T, MacLeod PJ et al (2004) A previously unidentified MECP2 open reading frame defines a new protein isoform relevant to Rett syndrome. Nat Genet 36(4):339–341
    • (2004) Nat Genet , vol.36 , Issue.4 , pp. 339-341
    • Mnatzakanian, G.N.1    Lohi, H.2    Munteanu, I.3    Alfred, S.E.4    Yamada, T.5    MacLeod, P.J.6
  • 38
    • 2542481314 scopus 로고    scopus 로고
    • The major form of MeCP2 has a novel N-terminus generated by alternative splicing
    • PID: 15034150
    • Kriaucionis S, Bird A (2004) The major form of MeCP2 has a novel N-terminus generated by alternative splicing. Nucleic Acids Res 32(5):1818–1823
    • (2004) Nucleic Acids Res , vol.32 , Issue.5 , pp. 1818-1823
    • Kriaucionis, S.1    Bird, A.2
  • 39
    • 0342437491 scopus 로고    scopus 로고
    • MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin
    • PID: 9038338
    • Nan X, Campoy FJ, Bird A (1997) MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin. Cell 88(4):471–481
    • (1997) Cell , vol.88 , Issue.4 , pp. 471-481
    • Nan, X.1    Campoy, F.J.2    Bird, A.3
  • 40
    • 84858327532 scopus 로고    scopus 로고
    • Linking epigenetics to human disease and Rett syndrome: the emerging novel and challenging concepts in MeCP2 research
    • PID: 22474603
    • Zachariah RM, Rastegar M (2012) Linking epigenetics to human disease and Rett syndrome: the emerging novel and challenging concepts in MeCP2 research. Neural Plast 2012:415825
    • (2012) Neural Plast , vol.2012 , pp. 415825
    • Zachariah, R.M.1    Rastegar, M.2
  • 41
    • 84896991213 scopus 로고    scopus 로고
    • Brain region-specific expression of MeCP2 isoforms correlates with DNA methylation within Mecp2 regulatory elements
    • PID: 24594659
    • Olson CO, Zachariah RM, Ezeonwuka CD, Liyanage VR, Rastegar M (2014) Brain region-specific expression of MeCP2 isoforms correlates with DNA methylation within Mecp2 regulatory elements. PLoS One 9(3):e90645
    • (2014) PLoS One , vol.9 , Issue.3 , pp. e90645
    • Olson, C.O.1    Zachariah, R.M.2    Ezeonwuka, C.D.3    Liyanage, V.R.4    Rastegar, M.5
  • 42
    • 34247197220 scopus 로고    scopus 로고
    • Differential distribution of the MeCP2 splice variants in the postnatal mouse brain
    • PID: 17278130
    • Dragich JM, Kim YH, Arnold AP, Schanen NC (2007) Differential distribution of the MeCP2 splice variants in the postnatal mouse brain. J Comp Neurol 501(4):526–542
    • (2007) J Comp Neurol , vol.501 , Issue.4 , pp. 526-542
    • Dragich, J.M.1    Kim, Y.H.2    Arnold, A.P.3    Schanen, N.C.4
  • 43
    • 84869787995 scopus 로고    scopus 로고
    • Novel MeCP2 isoform-specific antibody reveals the endogenous MeCP2E1 expression in murine brain, primary neurons and astrocytes
    • PID: 23185431
    • Zachariah RM, Olson CO, Ezeonwuka C, Rastegar M (2012) Novel MeCP2 isoform-specific antibody reveals the endogenous MeCP2E1 expression in murine brain, primary neurons and astrocytes. PLoS One 7(11):e49763
    • (2012) PLoS One , vol.7 , Issue.11 , pp. e49763
    • Zachariah, R.M.1    Olson, C.O.2    Ezeonwuka, C.3    Rastegar, M.4
  • 44
    • 83255185186 scopus 로고    scopus 로고
    • Transgenic complementation of MeCP2 deficiency: phenotypic rescue of Mecp2-null mice by isoform-specific transgenes
    • PID: 21829232
    • Kerr B, Soto CJ, Saez M, Abrams A, Walz K, Young JI (2012) Transgenic complementation of MeCP2 deficiency: phenotypic rescue of Mecp2-null mice by isoform-specific transgenes. Eur Journal Hum Genet EJHG 20(1):69–76
    • (2012) Eur Journal Hum Genet EJHG , vol.20 , Issue.1 , pp. 69-76
    • Kerr, B.1    Soto, C.J.2    Saez, M.3    Abrams, A.4    Walz, K.5    Young, J.I.6
  • 45
    • 69449090636 scopus 로고    scopus 로고
    • MECP2 isoform-specific vectors with regulated expression for Rett syndrome gene therapy
    • PID: 19710912
    • Rastegar M, Hotta A, Pasceri P, Makarem M, Cheung AY, Elliott S et al (2009) MECP2 isoform-specific vectors with regulated expression for Rett syndrome gene therapy. PLoS One 4(8):e6810
    • (2009) PLoS One , vol.4 , Issue.8 , pp. e6810
    • Rastegar, M.1    Hotta, A.2    Pasceri, P.3    Makarem, M.4    Cheung, A.Y.5    Elliott, S.6
  • 46
    • 4444319404 scopus 로고    scopus 로고
    • Suppression of MeCP2beta expression inhibits neurite extension in PC12 cells
    • PID: 15350542
    • Cusack SM, Rohn TT, Medeck RJ, Irwin KM, Brown RJ, Mercer LM et al (2004) Suppression of MeCP2beta expression inhibits neurite extension in PC12 cells. Exp Cell Res 299(2):442–453
    • (2004) Exp Cell Res , vol.299 , Issue.2 , pp. 442-453
    • Cusack, S.M.1    Rohn, T.T.2    Medeck, R.J.3    Irwin, K.M.4    Brown, R.J.5    Mercer, L.M.6
  • 47
    • 84857315949 scopus 로고    scopus 로고
    • Isoform-specific toxicity of Mecp2 in postmitotic neurons: suppression of neurotoxicity by FoxG1
    • Dastidar SG, Bardai FH, Ma C, Price V, Rawat V, Verma P et al (2012) Isoform-specific toxicity of Mecp2 in postmitotic neurons: suppression of neurotoxicity by FoxG1. J Neurosci Off J Soc Neurosci 32(8):2846–2855
    • (2012) J Neurosci Off J Soc Neurosci , vol.32 , Issue.8 , pp. 2846-2855
    • Dastidar, S.G.1    Bardai, F.H.2    Ma, C.3    Price, V.4    Rawat, V.5    Verma, P.6
  • 48
    • 84887526206 scopus 로고    scopus 로고
    • Decitabine alters the expression of Mecp2 isoforms via dynamic DNA methylation at the Mecp2 regulatory elements in neural stem cells
    • PID: 24238559
    • Liyanage VR, Zachariah RM, Rastegar M (2013) Decitabine alters the expression of Mecp2 isoforms via dynamic DNA methylation at the Mecp2 regulatory elements in neural stem cells. Mol Autism 4(1):46
    • (2013) Mol Autism , vol.4 , Issue.1 , pp. 46
    • Liyanage, V.R.1    Zachariah, R.M.2    Rastegar, M.3
  • 49
    • 84880335431 scopus 로고    scopus 로고
    • A synonymous change, p.Gly16Gly in MECP2 Exon 1, causes a cryptic splice event in a Rett syndrome patient
    • PID: 23866855
    • Sheikh TI, Mittal K, Willis MJ, Vincent JB (2013) A synonymous change, p.Gly16Gly in MECP2 Exon 1, causes a cryptic splice event in a Rett syndrome patient. Orphanet J Rare Dis 8:108
    • (2013) Orphanet J Rare Dis , vol.8 , pp. 108
    • Sheikh, T.I.1    Mittal, K.2    Willis, M.J.3    Vincent, J.B.4
  • 50
    • 33745241820 scopus 로고    scopus 로고
    • Lost in translation: translational interference from a recurrent mutation in exon 1 of MECP2
    • PID: 16155192
    • Saxena A, de Lagarde D, Leonard H, Williamson SL, Vasudevan V, Christodoulou J et al (2006) Lost in translation: translational interference from a recurrent mutation in exon 1 of MECP2. J Med Genet 43(6):470–477
    • (2006) J Med Genet , vol.43 , Issue.6 , pp. 470-477
    • Saxena, A.1    de Lagarde, D.2    Leonard, H.3    Williamson, S.L.4    Vasudevan, V.5    Christodoulou, J.6
  • 51
    • 0026658662 scopus 로고
    • Characterization of MeCP2, a vertebrate DNA binding protein with affinity for methylated DNA
    • PID: 1408825
    • Meehan RR, Lewis JD, Bird AP (1992) Characterization of MeCP2, a vertebrate DNA binding protein with affinity for methylated DNA. Nucleic Acids Res 20(19):5085–5092
    • (1992) Nucleic Acids Res , vol.20 , Issue.19 , pp. 5085-5092
    • Meehan, R.R.1    Lewis, J.D.2    Bird, A.P.3
  • 52
    • 79952698982 scopus 로고    scopus 로고
    • The role of MeCP2 in CNS development and function
    • PID: 20515694
    • Na ES, Monteggia LM (2011) The role of MeCP2 in CNS development and function. Horm Behav 59(3):364–368
    • (2011) Horm Behav , vol.59 , Issue.3 , pp. 364-368
    • Na, E.S.1    Monteggia, L.M.2
  • 53
    • 77956396618 scopus 로고    scopus 로고
    • A novel transcriptional regulator of myelin gene expression: implications for neurodevelopmental disorders
    • PID: 20697302
    • Vora P, Mina R, Namaka M, Frost EE (2010) A novel transcriptional regulator of myelin gene expression: implications for neurodevelopmental disorders. Neuroreport 21(14):917–921
    • (2010) Neuroreport , vol.21 , Issue.14 , pp. 917-921
    • Vora, P.1    Mina, R.2    Namaka, M.3    Frost, E.E.4
  • 54
    • 0032574977 scopus 로고    scopus 로고
    • Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
    • PID: 9620804
    • Nan X, Ng HH, Johnson CA, Laherty CD, Turner BM, Eisenman RN et al (1998) Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex. Nature 393(6683):386–389
    • (1998) Nature , vol.393 , Issue.6683 , pp. 386-389
    • Nan, X.1    Ng, H.H.2    Johnson, C.A.3    Laherty, C.D.4    Turner, B.M.5    Eisenman, R.N.6
  • 55
    • 0032450550 scopus 로고    scopus 로고
    • Histone deacetylase directs the dominant silencing of transcription in chromatin: association with MeCP2 and the Mi-2 chromodomain SWI/SNF ATPase
    • PID: 10384308
    • Wade PA, Jones PL, Vermaak D, Veenstra GJ, Imhof A, Sera T et al (1998) Histone deacetylase directs the dominant silencing of transcription in chromatin: association with MeCP2 and the Mi-2 chromodomain SWI/SNF ATPase. Cold Spring Harb Symp Quant Biol 63:435–445
    • (1998) Cold Spring Harb Symp Quant Biol , vol.63 , pp. 435-445
    • Wade, P.A.1    Jones, P.L.2    Vermaak, D.3    Veenstra, G.J.4    Imhof, A.5    Sera, T.6
  • 56
    • 0031617297 scopus 로고    scopus 로고
    • Gene silencing by methyl-CpG-binding proteins
    • PID: 9601009, discussion −21, 46–50
    • Nan X, Cross S, Bird A (1998) Gene silencing by methyl-CpG-binding proteins. Novartis Found Symp 214:6–16, discussion −21, 46–50
    • (1998) Novartis Found Symp , vol.214 , pp. 6-16
    • Nan, X.1    Cross, S.2    Bird, A.3
  • 57
    • 0031837109 scopus 로고    scopus 로고
    • Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription
    • PID: 9620779
    • Jones PL, Veenstra GJ, Wade PA, Vermaak D, Kass SU, Landsberger N et al (1998) Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription. Nat Genet 19(2):187–191
    • (1998) Nat Genet , vol.19 , Issue.2 , pp. 187-191
    • Jones, P.L.1    Veenstra, G.J.2    Wade, P.A.3    Vermaak, D.4    Kass, S.U.5    Landsberger, N.6
  • 58
    • 0034657578 scopus 로고    scopus 로고
    • Histone deacetylase-independent transcriptional repression by methyl-CpG-binding protein 2
    • PID: 10773092
    • Yu F, Thiesen J, Stratling WH (2000) Histone deacetylase-independent transcriptional repression by methyl-CpG-binding protein 2. Nucleic Acids Res 28(10):2201–2206
    • (2000) Nucleic Acids Res , vol.28 , Issue.10 , pp. 2201-2206
    • Yu, F.1    Thiesen, J.2    Stratling, W.H.3
  • 59
    • 45749147105 scopus 로고    scopus 로고
    • MeCP2 knockdown reveals DNA methylation-independent gene repression of target genes in living cells and a bias in the cellular location of target gene products
    • PID: 18506103
    • Yakabe S, Soejima H, Yatsuki H, Tominaga H, Zhao W, Higashimoto K et al (2008) MeCP2 knockdown reveals DNA methylation-independent gene repression of target genes in living cells and a bias in the cellular location of target gene products. Genes Genet Syst 83(2):199–208
    • (2008) Genes Genet Syst , vol.83 , Issue.2 , pp. 199-208
    • Yakabe, S.1    Soejima, H.2    Yatsuki, H.3    Tominaga, H.4    Zhao, W.5    Higashimoto, K.6
  • 60
    • 0242332183 scopus 로고    scopus 로고
    • Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2
    • PID: 14593183
    • Chen WG, Chang Q, Lin Y, Meissner A, West AE, Griffith EC et al (2003) Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2. Science 302(5646):885–889
    • (2003) Science , vol.302 , Issue.5646 , pp. 885-889
    • Chen, W.G.1    Chang, Q.2    Lin, Y.3    Meissner, A.4    West, A.E.5    Griffith, E.C.6
  • 61
    • 31444434393 scopus 로고    scopus 로고
    • The disease progression of mecp2 mutant mice is affected by the level of BDNF expression
    • PID: 16446138
    • Chang Q, Khare G, Dani V, Nelson S, Jaenisch R (2006) The disease progression of mecp2 mutant mice is affected by the level of BDNF expression. Neuron 49(3):341–348
    • (2006) Neuron , vol.49 , Issue.3 , pp. 341-348
    • Chang, Q.1    Khare, G.2    Dani, V.3    Nelson, S.4    Jaenisch, R.5
  • 62
    • 84891720484 scopus 로고    scopus 로고
    • Exploring the role of nerve growth factor in multiple sclerosis: implications in myelin repair
    • PID: 23844684
    • Acosta CM, Cortes C, MacPhee H, Namaka MP (2013) Exploring the role of nerve growth factor in multiple sclerosis: implications in myelin repair. CNS Neurol Disord Drug Targets 12(8):1242–1256
    • (2013) CNS Neurol Disord Drug Targets , vol.12 , Issue.8 , pp. 1242-1256
    • Acosta, C.M.1    Cortes, C.2    MacPhee, H.3    Namaka, M.P.4
  • 63
    • 0032830639 scopus 로고    scopus 로고
    • Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2
    • PID: 10508514
    • Amir RE, Van den Veyver IB, Wan M, Tran CQ, Francke U, Zoghbi HY (1999) Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2. Nat Genet 23(2):185–188
    • (1999) Nat Genet , vol.23 , Issue.2 , pp. 185-188
    • Amir, R.E.1    Van den Veyver, I.B.2    Wan, M.3    Tran, C.Q.4    Francke, U.5    Zoghbi, H.Y.6
  • 65
    • 34247095504 scopus 로고    scopus 로고
    • Reduced MeCP2 expression is frequent in autism frontal cortex and correlates with aberrant MECP2 promoter methylation
    • PID: 17486179
    • Nagarajan RP, Hogart AR, Gwye Y, Martin MR, LaSalle JM (2006) Reduced MeCP2 expression is frequent in autism frontal cortex and correlates with aberrant MECP2 promoter methylation. Epigenetics 1(4):e1–e11
    • (2006) Epigenetics , vol.1 , Issue.4 , pp. e1-e11
    • Nagarajan, R.P.1    Hogart, A.R.2    Gwye, Y.3    Martin, M.R.4    LaSalle, J.M.5
  • 66
    • 0034540747 scopus 로고    scopus 로고
    • Spectrum of mutations in the MECP2 gene in patients with infantile autism and Rett syndrome
    • PID: 11106359
    • Lam CW, Yeung WL, Ko CH, Poon PM, Tong SF, Chan KY et al (2000) Spectrum of mutations in the MECP2 gene in patients with infantile autism and Rett syndrome. J Med Genet 37(12):E41
    • (2000) J Med Genet , vol.37 , Issue.12 , pp. E41
    • Lam, C.W.1    Yeung, W.L.2    Ko, C.H.3    Poon, P.M.4    Tong, S.F.5    Chan, K.Y.6
  • 67
    • 84871525988 scopus 로고    scopus 로고
    • MeCP2 modulates the canonical Wnt pathway activation by targeting SFRP4 in rheumatoid arthritis fibroblast-like synoviocytes in rats
    • PID: 23200852
    • Miao CG, Huang C, Huang Y, Yang YY, He X, Zhang L et al (2013) MeCP2 modulates the canonical Wnt pathway activation by targeting SFRP4 in rheumatoid arthritis fibroblast-like synoviocytes in rats. Cell Signal 25(3):598–608
    • (2013) Cell Signal , vol.25 , Issue.3 , pp. 598-608
    • Miao, C.G.1    Huang, C.2    Huang, Y.3    Yang, Y.Y.4    He, X.5    Zhang, L.6
  • 69
    • 34848917279 scopus 로고    scopus 로고
    • Retrovirus silencing by an epigenetic TRIM
    • PID: 17923079
    • Ellis J, Hotta A, Rastegar M (2007) Retrovirus silencing by an epigenetic TRIM. Cell 131(1):13–14
    • (2007) Cell , vol.131 , Issue.1 , pp. 13-14
    • Ellis, J.1    Hotta, A.2    Rastegar, M.3
  • 71
    • 77956616754 scopus 로고    scopus 로고
    • Epigenetic control of Hox genes during neurogenesis, development, and disease
    • Barber BA, Rastegar M (2010) Epigenetic control of Hox genes during neurogenesis, development, and disease. Ann Anat Anat Anz Off Organ Anat Ges 192(5):261–274
    • (2010) Ann Anat Anat Anz Off Organ Anat Ges , vol.192 , Issue.5 , pp. 261-274
    • Barber, B.A.1    Rastegar, M.2
  • 72
    • 80052461558 scopus 로고    scopus 로고
    • Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine
    • PID: 21778364
    • Ito S, Shen L, Dai Q, Wu SC, Collins LB, Swenberg JA et al (2011) Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine. Science 333(6047):1300–1303
    • (2011) Science , vol.333 , Issue.6047 , pp. 1300-1303
    • Ito, S.1    Shen, L.2    Dai, Q.3    Wu, S.C.4    Collins, L.B.5    Swenberg, J.A.6
  • 73
    • 2942594082 scopus 로고    scopus 로고
    • Cytosine methylation and CpG, TpG (CpA) and TpA frequencies
    • PID: 15177689
    • Jabbari K, Bernardi G (2004) Cytosine methylation and CpG, TpG (CpA) and TpA frequencies. Gene 333:143–149
    • (2004) Gene , vol.333 , pp. 143-149
    • Jabbari, K.1    Bernardi, G.2
  • 74
    • 84871563384 scopus 로고    scopus 로고
    • MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system
    • PID: 23260135
    • Mellen M, Ayata P, Dewell S, Kriaucionis S, Heintz N (2012) MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system. Cell 151(7):1417–1430
    • (2012) Cell , vol.151 , Issue.7 , pp. 1417-1430
    • Mellen, M.1    Ayata, P.2    Dewell, S.3    Kriaucionis, S.4    Heintz, N.5
  • 75
    • 84858327532 scopus 로고    scopus 로고
    • Linking epigenetics to human disease and Rett syndrome: the emerging novel and challenging concepts in MeCP2 research
    • Zachariah RM, Rastegar M (2012) Linking epigenetics to human disease and Rett syndrome: the emerging novel and challenging concepts in MeCP2 research. Neural Plast 2012:10
    • (2012) Neural Plast , vol.2012 , pp. 10
    • Zachariah, R.M.1    Rastegar, M.2
  • 76
    • 45849105557 scopus 로고    scopus 로고
    • MeCP2, a key contributor to neurological disease, activates and represses transcription
    • PID: 18511691
    • Chahrour M, Jung SY, Shaw C, Zhou X, Wong ST, Qin J et al (2008) MeCP2, a key contributor to neurological disease, activates and represses transcription. Science 320(5880):1224–1229
    • (2008) Science , vol.320 , Issue.5880 , pp. 1224-1229
    • Chahrour, M.1    Jung, S.Y.2    Shaw, C.3    Zhou, X.4    Wong, S.T.5    Qin, J.6
  • 77
    • 84893740377 scopus 로고    scopus 로고
    • Distribution, recognition and regulation of non-CpG methylation in the adult mammalian brain
    • PID: 24362762
    • Guo JU, Su Y, Shin JH, Shin J, Li H, Xie B et al (2014) Distribution, recognition and regulation of non-CpG methylation in the adult mammalian brain. Nat Neurosci 17(2):215–222
    • (2014) Nat Neurosci , vol.17 , Issue.2 , pp. 215-222
    • Guo, J.U.1    Su, Y.2    Shin, J.H.3    Shin, J.4    Li, H.5    Xie, B.6
  • 79
    • 84891450164 scopus 로고    scopus 로고
    • Histone deacetylase sirtuin 1 deacetylates IRF1 protein and programs dendritic cells to control Th17 protein differentiation during autoimmune inflammation
    • PID: 24214980
    • Yang H, Lee SM, Gao B, Zhang J, Fang D (2013) Histone deacetylase sirtuin 1 deacetylates IRF1 protein and programs dendritic cells to control Th17 protein differentiation during autoimmune inflammation. J Biol Chem 288(52):37256–37266
    • (2013) J Biol Chem , vol.288 , Issue.52 , pp. 37256-37266
    • Yang, H.1    Lee, S.M.2    Gao, B.3    Zhang, J.4    Fang, D.5
  • 80
    • 84860203756 scopus 로고    scopus 로고
    • Increased promoter methylation of the immune regulatory gene SHP-1 in leukocytes of multiple sclerosis subjects
    • PID: 22458980
    • Kumagai C, Kalman B, Middleton FA, Vyshkina T, Massa PT (2012) Increased promoter methylation of the immune regulatory gene SHP-1 in leukocytes of multiple sclerosis subjects. J Neuroimmunol 246(1–2):51–57
    • (2012) J Neuroimmunol , vol.246 , Issue.1-2 , pp. 51-57
    • Kumagai, C.1    Kalman, B.2    Middleton, F.A.3    Vyshkina, T.4    Massa, P.T.5
  • 81
    • 84890798859 scopus 로고    scopus 로고
    • Human endogenous retrovirus type W envelope protein inhibits oligodendroglial precursor cell differentiation
    • PID: 23836485
    • Kremer D, Schichel T, Forster M, Tzekova N, Bernard C, van der Valk P et al (2013) Human endogenous retrovirus type W envelope protein inhibits oligodendroglial precursor cell differentiation. Ann Neurol 74(5):721–732
    • (2013) Ann Neurol , vol.74 , Issue.5 , pp. 721-732
    • Kremer, D.1    Schichel, T.2    Forster, M.3    Tzekova, N.4    Bernard, C.5    van der Valk, P.6
  • 82
    • 77954086319 scopus 로고    scopus 로고
    • The human endogenous retrovirus link between genes and environment in multiple sclerosis and in multifactorial diseases associating neuroinflammation
    • PID: 19697163
    • Perron H, Lang A (2010) The human endogenous retrovirus link between genes and environment in multiple sclerosis and in multifactorial diseases associating neuroinflammation. Clin Rev Allergy Immunol 39(1):51–61
    • (2010) Clin Rev Allergy Immunol , vol.39 , Issue.1 , pp. 51-61
    • Perron, H.1    Lang, A.2
  • 84
    • 79957954734 scopus 로고    scopus 로고
    • The therapeutic potential of HDAC inhibitors in the treatment of multiple sclerosis
    • PID: 21373721
    • Faraco G, Cavone L, Chiarugi A (2011) The therapeutic potential of HDAC inhibitors in the treatment of multiple sclerosis. Mol Med 17(5–6):442–447
    • (2011) Mol Med , vol.17 , Issue.5-6 , pp. 442-447
    • Faraco, G.1    Cavone, L.2    Chiarugi, A.3
  • 85
    • 20444446595 scopus 로고    scopus 로고
    • Transcriptional therapy with the histone deacetylase inhibitor trichostatin A ameliorates experimental autoimmune encephalomyelitis
    • PID: 15885809
    • Camelo S, Iglesias AH, Hwang D, Due B, Ryu H, Smith K et al (2005) Transcriptional therapy with the histone deacetylase inhibitor trichostatin A ameliorates experimental autoimmune encephalomyelitis. J Neuroimmunol 164(1–2):10–21
    • (2005) J Neuroimmunol , vol.164 , Issue.1-2 , pp. 10-21
    • Camelo, S.1    Iglesias, A.H.2    Hwang, D.3    Due, B.4    Ryu, H.5    Smith, K.6
  • 86
    • 84864824870 scopus 로고    scopus 로고
    • Valproic acid ameliorates inflammation in experimental autoimmune encephalomyelitis rats
    • PID: 22800566
    • Zhang Z, Zhang ZY, Wu Y, Schluesener HJ (2012) Valproic acid ameliorates inflammation in experimental autoimmune encephalomyelitis rats. Neuroscience 221:140–150
    • (2012) Neuroscience , vol.221 , pp. 140-150
    • Zhang, Z.1    Zhang, Z.Y.2    Wu, Y.3    Schluesener, H.J.4
  • 87
    • 84891047375 scopus 로고    scopus 로고
    • Valproic Acid attenuates disease symptoms and increases endogenous myelin repair by recruiting neural stem cells and oligodendrocyte progenitors in experimental autoimmune encephalomyelitis
    • Pazhoohan S, Satarian L, Asghari AA, Salimi M, Kiani S, Mani AR et al (2014) Valproic Acid attenuates disease symptoms and increases endogenous myelin repair by recruiting neural stem cells and oligodendrocyte progenitors in experimental autoimmune encephalomyelitis. Neuro Degener Dis 13(1):45–52
    • (2014) Neuro Degener Dis , vol.13 , Issue.1 , pp. 45-52
    • Pazhoohan, S.1    Satarian, L.2    Asghari, A.A.3    Salimi, M.4    Kiani, S.5    Mani, A.R.6
  • 88
    • 84872318428 scopus 로고    scopus 로고
    • Vorinostat, a histone deacetylase inhibitor, suppresses dendritic cell function and ameliorates experimental autoimmune encephalomyelitis
    • PID: 23261766
    • Ge Z, Da Y, Xue Z, Zhang K, Zhuang H, Peng M et al (2013) Vorinostat, a histone deacetylase inhibitor, suppresses dendritic cell function and ameliorates experimental autoimmune encephalomyelitis. Exp Neurol 241:56–66
    • (2013) Exp Neurol , vol.241 , pp. 56-66
    • Ge, Z.1    Da, Y.2    Xue, Z.3    Zhang, K.4    Zhuang, H.5    Peng, M.6
  • 89
    • 84867719585 scopus 로고    scopus 로고
    • Differential regulation of CD4(+) T helper cell responses by curcumin in experimental autoimmune encephalomyelitis
    • PID: 22402368
    • Kanakasabai S, Casalini E, Walline CC, Mo C, Chearwae W, Bright JJ (2012) Differential regulation of CD4(+) T helper cell responses by curcumin in experimental autoimmune encephalomyelitis. J Nutr Biochem 23(11):1498–1507
    • (2012) J Nutr Biochem , vol.23 , Issue.11 , pp. 1498-1507
    • Kanakasabai, S.1    Casalini, E.2    Walline, C.C.3    Mo, C.4    Chearwae, W.5    Bright, J.J.6
  • 90
    • 80755153600 scopus 로고    scopus 로고
    • Ameliorative effects of curcumin against renal injuries mediated by inducible nitric oxide synthase and nuclear factor kappa B during gentamicin-induced toxicity in Wistar rats
    • PID: 21925163
    • Manikandan R, Beulaja M, Thiagarajan R, Priyadarsini A, Saravanan R, Arumugam M (2011) Ameliorative effects of curcumin against renal injuries mediated by inducible nitric oxide synthase and nuclear factor kappa B during gentamicin-induced toxicity in Wistar rats. Eur J Pharmacol 670(2–3):578–585
    • (2011) Eur J Pharmacol , vol.670 , Issue.2-3 , pp. 578-585
    • Manikandan, R.1    Beulaja, M.2    Thiagarajan, R.3    Priyadarsini, A.4    Saravanan, R.5    Arumugam, M.6
  • 91
    • 63549122337 scopus 로고    scopus 로고
    • Amelioration of experimental autoimmune encephalomyelitis by curcumin treatment through inhibition of IL-17 production
    • PID: 19539560
    • Xie L, Li XK, Funeshima-Fuji N, Kimura H, Matsumoto Y, Isaka Y et al (2009) Amelioration of experimental autoimmune encephalomyelitis by curcumin treatment through inhibition of IL-17 production. Int Immunopharmacol 9(5):575–581
    • (2009) Int Immunopharmacol , vol.9 , Issue.5 , pp. 575-581
    • Xie, L.1    Li, X.K.2    Funeshima-Fuji, N.3    Kimura, H.4    Matsumoto, Y.5    Isaka, Y.6
  • 92
    • 0242300612 scopus 로고    scopus 로고
    • DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation
    • PID: 14593184
    • Martinowich K, Hattori D, Wu H, Fouse S, He F, Hu Y et al (2003) DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation. Science 302(5646):890–893
    • (2003) Science , vol.302 , Issue.5646 , pp. 890-893
    • Martinowich, K.1    Hattori, D.2    Wu, H.3    Fouse, S.4    He, F.5    Hu, Y.6
  • 93
    • 84864387128 scopus 로고    scopus 로고
    • The role of dorsal root ganglia activation and brain-derived neurotrophic factor in multiple sclerosis
    • PID: 22050733
    • Zhu W, Frost EE, Begum F, Vora P, Au K, Gong Y et al (2012) The role of dorsal root ganglia activation and brain-derived neurotrophic factor in multiple sclerosis. J Cell Mol Med 16(8):1856–1865
    • (2012) J Cell Mol Med , vol.16 , Issue.8 , pp. 1856-1865
    • Zhu, W.1    Frost, E.E.2    Begum, F.3    Vora, P.4    Au, K.5    Gong, Y.6
  • 94
    • 84878804639 scopus 로고    scopus 로고
    • Elevation of tumor necrosis factor alpha in dorsal root ganglia and spinal cord is associated with neuroimmune modulation of pain in an animal model of multiple sclerosis
    • Begum F, Zhu W, Cortes C, Macneil B, Namaka M (2013) Elevation of tumor necrosis factor alpha in dorsal root ganglia and spinal cord is associated with neuroimmune modulation of pain in an animal model of multiple sclerosis. J Neuroimmune Pharmacol Off J Soc NeuroImmune Pharmacol 8(3):677–690
    • (2013) J Neuroimmune Pharmacol Off J Soc NeuroImmune Pharmacol , vol.8 , Issue.3 , pp. 677-690
    • Begum, F.1    Zhu, W.2    Cortes, C.3    Macneil, B.4    Namaka, M.5
  • 95
    • 33747379123 scopus 로고    scopus 로고
    • Up-regulation of BDNF in astrocytes by TNF-α: a case for the neuroprotective role of cytokine
    • PID: 18040799
    • Saha R, Liu X, Pahan K (2006) Up-regulation of BDNF in astrocytes by TNF-α: a case for the neuroprotective role of cytokine. J Neuroimmune Pharmacol 1(3):212–222
    • (2006) J Neuroimmune Pharmacol , vol.1 , Issue.3 , pp. 212-222
    • Saha, R.1    Liu, X.2    Pahan, K.3
  • 96
    • 0033523473 scopus 로고    scopus 로고
    • Learning abilities, NGF and BDNF brain levels in two lines of TNF-alpha transgenic mice, one characterized by neurological disorders, the other phenotypically normal
    • PID: 10517960
    • Aloe L, Properzi F, Probert L, Akassoglou K, Kassiotis G, Micera A et al (1999) Learning abilities, NGF and BDNF brain levels in two lines of TNF-alpha transgenic mice, one characterized by neurological disorders, the other phenotypically normal. Brain Res 840(1–2):125–137
    • (1999) Brain Res , vol.840 , Issue.1-2 , pp. 125-137
    • Aloe, L.1    Properzi, F.2    Probert, L.3    Akassoglou, K.4    Kassiotis, G.5    Micera, A.6
  • 97
    • 33749246536 scopus 로고    scopus 로고
    • The role of TNF-alpha and its receptors in the production of NGF and GDNF by astrocytes
    • PID: 16956589
    • Kuno R, Yoshida Y, Nitta A, Nabeshima T, Wang J, Sonobe Y et al (2006) The role of TNF-alpha and its receptors in the production of NGF and GDNF by astrocytes. Brain Res 1116(1):12–18
    • (2006) Brain Res , vol.1116 , Issue.1 , pp. 12-18
    • Kuno, R.1    Yoshida, Y.2    Nitta, A.3    Nabeshima, T.4    Wang, J.5    Sonobe, Y.6
  • 98
    • 0028023450 scopus 로고
    • Nerve growth factor contributes to the generation of inflammatory sensory hypersensitivity
    • PID: 7530342
    • Woolf CJ, Safieh-Garabedian B, Ma QP, Crilly P, Winter J (1994) Nerve growth factor contributes to the generation of inflammatory sensory hypersensitivity. Neuroscience 62(2):327–331
    • (1994) Neuroscience , vol.62 , Issue.2 , pp. 327-331
    • Woolf, C.J.1    Safieh-Garabedian, B.2    Ma, Q.P.3    Crilly, P.4    Winter, J.5
  • 99
    • 84906569100 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor and rett syndrome
    • PID: 24668484
    • Katz DM (2014) Brain-derived neurotrophic factor and rett syndrome. Handb Exp Pharmacol 220:481–495
    • (2014) Handb Exp Pharmacol , vol.220 , pp. 481-495
    • Katz, D.M.1
  • 100
    • 5644251587 scopus 로고    scopus 로고
    • Cleavage of proBDNF by tPA/plasmin is essential for long-term hippocampal plasticity
    • PID: 15486301
    • Pang PT, Teng HK, Zaitsev E, Woo NT, Sakata K, Zhen S et al (2004) Cleavage of proBDNF by tPA/plasmin is essential for long-term hippocampal plasticity. Science 306(5695):487–491
    • (2004) Science , vol.306 , Issue.5695 , pp. 487-491
    • Pang, P.T.1    Teng, H.K.2    Zaitsev, E.3    Woo, N.T.4    Sakata, K.5    Zhen, S.6
  • 101
    • 0028109727 scopus 로고
    • Characterisation of neurotrophin dimers and monomers
    • PID: 7957235
    • Kolbeck R, Jungbluth S, Barde YA (1994) Characterisation of neurotrophin dimers and monomers. Eur J Biochem 225(3):995–1003
    • (1994) Eur J Biochem , vol.225 , Issue.3 , pp. 995-1003
    • Kolbeck, R.1    Jungbluth, S.2    Barde, Y.A.3
  • 102
    • 0030050741 scopus 로고    scopus 로고
    • Cellular processing of the neurotrophin precursors of NT3 and BDNF by the mammalian proprotein convertases
    • PID: 8603699
    • Seidah NG, Benjannet S, Pareek S, Chretien M, Murphy RA (1996) Cellular processing of the neurotrophin precursors of NT3 and BDNF by the mammalian proprotein convertases. FEBS Lett 379(3):247–250
    • (1996) FEBS Lett , vol.379 , Issue.3 , pp. 247-250
    • Seidah, N.G.1    Benjannet, S.2    Pareek, S.3    Chretien, M.4    Murphy, R.A.5
  • 103
    • 0033081042 scopus 로고    scopus 로고
    • Biochemical and functional interactions between the neurotrophin receptors trk and p75NTR
    • PID: 9927421
    • Bibel M, Hoppe E, Barde YA (1999) Biochemical and functional interactions between the neurotrophin receptors trk and p75NTR. EMBO J 18(3):616–622
    • (1999) EMBO J , vol.18 , Issue.3 , pp. 616-622
    • Bibel, M.1    Hoppe, E.2    Barde, Y.A.3
  • 104
    • 0035369840 scopus 로고    scopus 로고
    • Trk receptors: mediators of neurotrophin action
    • PID: 11399424
    • Patapoutian A, Reichardt LF (2001) Trk receptors: mediators of neurotrophin action. Curr Opin Neurobiol 11(3):272–280
    • (2001) Curr Opin Neurobiol , vol.11 , Issue.3 , pp. 272-280
    • Patapoutian, A.1    Reichardt, L.F.2
  • 105
    • 0035369111 scopus 로고    scopus 로고
    • The uniqueness of being a neurotrophin receptor
    • PID: 11399425
    • Lee FS, Kim AH, Khursigara G, Chao MV (2001) The uniqueness of being a neurotrophin receptor. Curr Opin Neurobiol 11(3):281–286
    • (2001) Curr Opin Neurobiol , vol.11 , Issue.3 , pp. 281-286
    • Lee, F.S.1    Kim, A.H.2    Khursigara, G.3    Chao, M.V.4
  • 106
    • 5744233877 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor
    • PID: 15518235
    • Binder DK, Scharfman HE (2004) Brain-derived neurotrophic factor. Growth Factors 22(3):123–131
    • (2004) Growth Factors , vol.22 , Issue.3 , pp. 123-131
    • Binder, D.K.1    Scharfman, H.E.2
  • 107
    • 77949721758 scopus 로고    scopus 로고
    • Neurotrophin receptors: old friends with new partners
    • PID: 20186712
    • Schecterson LC, Bothwell M (2010) Neurotrophin receptors: old friends with new partners. Dev Neurobiol 70(5):332–338
    • (2010) Dev Neurobiol , vol.70 , Issue.5 , pp. 332-338
    • Schecterson, L.C.1    Bothwell, M.2
  • 108
    • 0032586026 scopus 로고    scopus 로고
    • The interaction of neurotrophins with the p75NTR common neurotrophin receptor: a comprehensive molecular modeling study
    • PID: 10595525
    • Shamovsky IL, Ross GM, Riopelle RJ, Weaver DF (1999) The interaction of neurotrophins with the p75NTR common neurotrophin receptor: a comprehensive molecular modeling study. Protein Sci 8(11):2223–2233
    • (1999) Protein Sci , vol.8 , Issue.11 , pp. 2223-2233
    • Shamovsky, I.L.1    Ross, G.M.2    Riopelle, R.J.3    Weaver, D.F.4
  • 109
    • 66649136257 scopus 로고    scopus 로고
    • Multiple roles of the p75 neurotrophin receptor in the nervous system
    • PID: 19383220
    • Chen Y, Zeng J, Cen L, Chen Y, Wang X, Yao G et al (2009) Multiple roles of the p75 neurotrophin receptor in the nervous system. J Int Med Res 37(2):281–288
    • (2009) J Int Med Res , vol.37 , Issue.2 , pp. 281-288
    • Chen, Y.1    Zeng, J.2    Cen, L.3    Chen, Y.4    Wang, X.5    Yao, G.6
  • 110
    • 0037044576 scopus 로고    scopus 로고
    • The neurotrophin receptor p75NTR as a positive modulator of myelination
    • PID: 12424382
    • Cosgaya JM, Chan JR, Shooter EM (2002) The neurotrophin receptor p75NTR as a positive modulator of myelination. Science 298(5596):1245–1248
    • (2002) Science , vol.298 , Issue.5596 , pp. 1245-1248
    • Cosgaya, J.M.1    Chan, J.R.2    Shooter, E.M.3
  • 111
    • 0036983427 scopus 로고    scopus 로고
    • Immunocytological studies of L-MAG expression regulation during myelination of embryonic brain cell cocultures
    • PID: 12697987
    • Keita M, Magy L, Heape A, Richard L, Piaser M, Vallat JM (2002) Immunocytological studies of L-MAG expression regulation during myelination of embryonic brain cell cocultures. Dev Neurosci 24(6):495–503
    • (2002) Dev Neurosci , vol.24 , Issue.6 , pp. 495-503
    • Keita, M.1    Magy, L.2    Heape, A.3    Richard, L.4    Piaser, M.5    Vallat, J.M.6
  • 112
    • 34547641252 scopus 로고    scopus 로고
    • The neurotrophin receptor p75NTR in Schwann cells is implicated in remyelination and motor recovery after peripheral nerve injury
    • PID: 17600367
    • Tomita K, Kubo T, Matsuda K, Fujiwara T, Yano K, Winograd JM et al (2007) The neurotrophin receptor p75NTR in Schwann cells is implicated in remyelination and motor recovery after peripheral nerve injury. Glia 55(11):1199–1208
    • (2007) Glia , vol.55 , Issue.11 , pp. 1199-1208
    • Tomita, K.1    Kubo, T.2    Matsuda, K.3    Fujiwara, T.4    Yano, K.5    Winograd, J.M.6
  • 113
    • 45949086514 scopus 로고    scopus 로고
    • Oligodendroglial cells and neurotrophins: a polyphonic cantata in major and minor
    • PID: 18327658
    • Althaus HH, Kloppner S, Klopfleisch S, Schmitz M (2008) Oligodendroglial cells and neurotrophins: a polyphonic cantata in major and minor. J Mol Neurosci 35(1):65–79
    • (2008) J Mol Neurosci , vol.35 , Issue.1 , pp. 65-79
    • Althaus, H.H.1    Kloppner, S.2    Klopfleisch, S.3    Schmitz, M.4
  • 114
    • 0029819746 scopus 로고    scopus 로고
    • Nerve growth factor and neurotrophin-3 differentially regulate the proliferation and survival of developing Rat brain oligodendrocytes
    • PID: 8815922
    • Cohen RI, Marmur R, Norton WT, Mehler MF, Kessler JA (1996) Nerve growth factor and neurotrophin-3 differentially regulate the proliferation and survival of developing Rat brain oligodendrocytes. J Neurosci 16(20):6433–6442
    • (1996) J Neurosci , vol.16 , Issue.20 , pp. 6433-6442
    • Cohen, R.I.1    Marmur, R.2    Norton, W.T.3    Mehler, M.F.4    Kessler, J.A.5
  • 115
    • 0033544034 scopus 로고    scopus 로고
    • Up-regulated p75NTR neurotrophin receptor on glial cells in MS plaques
    • PID: 10563612
    • Dowling P, Ming X, Raval S, Husar W, Casaccia-Bonnefil P, Chao M et al (1999) Up-regulated p75NTR neurotrophin receptor on glial cells in MS plaques. Neurology 53(8):1676–1682
    • (1999) Neurology , vol.53 , Issue.8 , pp. 1676-1682
    • Dowling, P.1    Ming, X.2    Raval, S.3    Husar, W.4    Casaccia-Bonnefil, P.5    Chao, M.6
  • 116
    • 27944438916 scopus 로고    scopus 로고
    • p75NTR independent oligodendrocyte death in cuprizone-induced demyelination in C57BL/6 mice
    • PID: 16281908
    • Copray JC, Kust BM, Mantingh-Otter I, Boddeke HW (2005) p75NTR independent oligodendrocyte death in cuprizone-induced demyelination in C57BL/6 mice. Neuropathol Appl Neurobiol 31(6):600–609
    • (2005) Neuropathol Appl Neurobiol , vol.31 , Issue.6 , pp. 600-609
    • Copray, J.C.1    Kust, B.M.2    Mantingh-Otter, I.3    Boddeke, H.W.4
  • 117
    • 53249134449 scopus 로고    scopus 로고
    • Glial reactions and degeneration of myelinated processes in spinal cord gray matter in chronic experimental autoimmune encephalomyelitis
    • PID: 18718511
    • Wu J, Ohlsson M, Warner EA, Loo KK, Hoang TX, Voskuhl RR et al (2008) Glial reactions and degeneration of myelinated processes in spinal cord gray matter in chronic experimental autoimmune encephalomyelitis. Neuroscience 156(3):586–596
    • (2008) Neuroscience , vol.156 , Issue.3 , pp. 586-596
    • Wu, J.1    Ohlsson, M.2    Warner, E.A.3    Loo, K.K.4    Hoang, T.X.5    Voskuhl, R.R.6
  • 118
    • 0037168106 scopus 로고    scopus 로고
    • ProNGF induces p75-mediated death of oligodendrocytes following spinal cord injury
    • PID: 12408842
    • Beattie MS, Harrington AW, Lee R, Kim JY, Boyce SL, Longo FM et al (2002) ProNGF induces p75-mediated death of oligodendrocytes following spinal cord injury. Neuron 36(3):375–386
    • (2002) Neuron , vol.36 , Issue.3 , pp. 375-386
    • Beattie, M.S.1    Harrington, A.W.2    Lee, R.3    Kim, J.Y.4    Boyce, S.L.5    Longo, F.M.6
  • 119
    • 6044247624 scopus 로고    scopus 로고
    • Expression of the low-affinity neurotrophin receptor, p75(NTR), is upregulated by oligodendroglial progenitors adjacent to the subventricular zone in response to demyelination
    • PID: 15326616
    • Petratos S, Gonzales MF, Azari MF, Marriott M, Minichiello RA, Shipham KA et al (2004) Expression of the low-affinity neurotrophin receptor, p75(NTR), is upregulated by oligodendroglial progenitors adjacent to the subventricular zone in response to demyelination. Glia 48(1):64–75
    • (2004) Glia , vol.48 , Issue.1 , pp. 64-75
    • Petratos, S.1    Gonzales, M.F.2    Azari, M.F.3    Marriott, M.4    Minichiello, R.A.5    Shipham, K.A.6
  • 120
    • 79952574938 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor promotes central nervous system myelination via a direct effect upon oligodendrocytes
    • Xiao J, Wong AW, Willingham MM, van den Buuse M, Kilpatrick TJ, Murray SS (2011) Brain-derived neurotrophic factor promotes central nervous system myelination via a direct effect upon oligodendrocytes. Neurosignals 18(3):186–202
    • (2011) Neurosignals , vol.18 , Issue.3 , pp. 186-202
    • Xiao, J.1    Wong, A.W.2    Willingham, M.M.3    van den Buuse, M.4    Kilpatrick, T.J.5    Murray, S.S.6
  • 121
    • 84865794247 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase 1/2 signaling promotes oligodendrocyte myelination in vitro
    • PID: 22784206
    • Xiao J, Ferner AH, Wong AW, Denham M, Kilpatrick TJ, Murray SS (2012) Extracellular signal-regulated kinase 1/2 signaling promotes oligodendrocyte myelination in vitro. J Neurochem 122(6):1167–1180
    • (2012) J Neurochem , vol.122 , Issue.6 , pp. 1167-1180
    • Xiao, J.1    Ferner, A.H.2    Wong, A.W.3    Denham, M.4    Kilpatrick, T.J.5    Murray, S.S.6
  • 122
    • 84874854906 scopus 로고    scopus 로고
    • Oligodendroglial expression of TrkB independently regulates myelination and progenitor cell proliferation
    • Wong AW, Xiao J, Kemper D, Kilpatrick TJ, Murray SS (2013) Oligodendroglial expression of TrkB independently regulates myelination and progenitor cell proliferation. J Neurosci Off J Soc Neurosci 33(11):4947–4957
    • (2013) J Neurosci Off J Soc Neurosci , vol.33 , Issue.11 , pp. 4947-4957
    • Wong, A.W.1    Xiao, J.2    Kemper, D.3    Kilpatrick, T.J.4    Murray, S.S.5
  • 123
    • 77952562399 scopus 로고    scopus 로고
    • BDNF+/− mice exhibit deficits in oligodendrocyte lineage cells of the basal forebrain
    • PID: 20091777
    • Vondran MW, Clinton-Luke P, Honeywell JZ, Dreyfus CF (2010) BDNF+/− mice exhibit deficits in oligodendrocyte lineage cells of the basal forebrain. Glia 58(7):848–856
    • (2010) Glia , vol.58 , Issue.7 , pp. 848-856
    • Vondran, M.W.1    Clinton-Luke, P.2    Honeywell, J.Z.3    Dreyfus, C.F.4
  • 124
    • 63049134270 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor effects on oligodendrocyte progenitors of the basal forebrain are mediated through trkB and the MAP kinase pathway
    • Van’t Veer A, Du Y, Fischer TZ, Boetig DR, Wood MR, Dreyfus CF (2009) Brain-derived neurotrophic factor effects on oligodendrocyte progenitors of the basal forebrain are mediated through trkB and the MAP kinase pathway. J Neurosci Res 87(1):69–78
    • (2009) J Neurosci Res , vol.87 , Issue.1 , pp. 69-78
    • Van’t Veer, A.1    Du, Y.2    Fischer, T.Z.3    Boetig, D.R.4    Wood, M.R.5    Dreyfus, C.F.6
  • 125
    • 80053639816 scopus 로고    scopus 로고
    • Levels of BDNF impact oligodendrocyte lineage cells following a cuprizone lesion
    • VonDran MW, Singh H, Honeywell JZ, Dreyfus CF (2011) Levels of BDNF impact oligodendrocyte lineage cells following a cuprizone lesion. J Neurosci Offi J Soc Neurosci 31(40):14182–14190
    • (2011) J Neurosci Offi J Soc Neurosci , vol.31 , Issue.40 , pp. 14182-14190
    • VonDran, M.W.1    Singh, H.2    Honeywell, J.Z.3    Dreyfus, C.F.4
  • 126
    • 0036154041 scopus 로고    scopus 로고
    • BDNF and gp145trkB in multiple sclerosis brain lesions: neuroprotective interactions between immune and neuronal cells?
    • PID: 11834594
    • Stadelmann C, Kerschensteiner M, Misgeld T, Bruck W, Hohlfeld R, Lassmann H (2002) BDNF and gp145trkB in multiple sclerosis brain lesions: neuroprotective interactions between immune and neuronal cells? Brain 125(Pt 1):75–85
    • (2002) Brain , vol.125 , pp. 75-85
    • Stadelmann, C.1    Kerschensteiner, M.2    Misgeld, T.3    Bruck, W.4    Hohlfeld, R.5    Lassmann, H.6
  • 127
    • 84958201875 scopus 로고    scopus 로고
    • Zhu W, Acosta C, MacNeil BJ, Klonisch T, Cortes C, Doupe M, Gong Y, Namaka M (2014) Spinal cord brain derived neurotrophic factor (BDNF) responsive cells in an experimental autoimmune encephalomyelitis (EAE) model of multiple sclerosis (MS): Implications in myelin repair. Res Immunol Int J (in press)
    • Zhu W, Acosta C, MacNeil BJ, Klonisch T, Cortes C, Doupe M, Gong Y, Namaka M (2014) Spinal cord brain derived neurotrophic factor (BDNF) responsive cells in an experimental autoimmune encephalomyelitis (EAE) model of multiple sclerosis (MS): Implications in myelin repair. Res Immunol Int J (in press)
  • 128
    • 58149311071 scopus 로고    scopus 로고
    • Higher expression of BDNF receptor gp145trkB is associated with lower apoptosis intensity in T cell lines in multiple sclerosis
    • PID: 18992902
    • De Santi L, Cantalupo L, Tassi M, Raspadori D, Cioni C, Annunziata P (2009) Higher expression of BDNF receptor gp145trkB is associated with lower apoptosis intensity in T cell lines in multiple sclerosis. J Neurol Sci 277(1–2):65–70
    • (2009) J Neurol Sci , vol.277 , Issue.1-2 , pp. 65-70
    • De Santi, L.1    Cantalupo, L.2    Tassi, M.3    Raspadori, D.4    Cioni, C.5    Annunziata, P.6
  • 129
    • 0038077547 scopus 로고    scopus 로고
    • Efficient central nervous system remyelination requires T cells
    • PID: 12731006
    • Bieber AJ, Kerr S, Rodriguez M (2003) Efficient central nervous system remyelination requires T cells. Ann Neurol 53(5):680–684
    • (2003) Ann Neurol , vol.53 , Issue.5 , pp. 680-684
    • Bieber, A.J.1    Kerr, S.2    Rodriguez, M.3
  • 131
    • 65249187147 scopus 로고    scopus 로고
    • BDNF exerts contrasting effects on peripheral myelination of NGF-dependent and BDNF-dependent DRG neurons
    • Xiao J, Wong AW, Willingham MM, Kaasinen SK, Hendry IA, Howitt J et al (2009) BDNF exerts contrasting effects on peripheral myelination of NGF-dependent and BDNF-dependent DRG neurons. J Neurosci Off J Soc Neurosci 29(13):4016–4022
    • (2009) J Neurosci Off J Soc Neurosci , vol.29 , Issue.13 , pp. 4016-4022
    • Xiao, J.1    Wong, A.W.2    Willingham, M.M.3    Kaasinen, S.K.4    Hendry, I.A.5    Howitt, J.6
  • 132
    • 84880162763 scopus 로고    scopus 로고
    • The benefits and detriments of macrophages/microglia in models of multiple sclerosis
    • PID: 23840244
    • Rawji KS, Yong VW (2013) The benefits and detriments of macrophages/microglia in models of multiple sclerosis. Clin Dev Immunol 2013:948976
    • (2013) Clin Dev Immunol , vol.2013 , pp. 948976
    • Rawji, K.S.1    Yong, V.W.2
  • 133
    • 0036310558 scopus 로고    scopus 로고
    • Alterations in metabolism and gene expression in brain regions during cuprizone-induced demyelination and remyelination
    • PID: 12091473
    • Jurevics H, Largent C, Hostettler J, Sammond DW, Matsushima GK, Kleindienst A et al (2002) Alterations in metabolism and gene expression in brain regions during cuprizone-induced demyelination and remyelination. J Neurochem 82(1):126–136
    • (2002) J Neurochem , vol.82 , Issue.1 , pp. 126-136
    • Jurevics, H.1    Largent, C.2    Hostettler, J.3    Sammond, D.W.4    Matsushima, G.K.5    Kleindienst, A.6
  • 134
    • 84873351615 scopus 로고    scopus 로고
    • Astrocytes regulate myelin clearance through recruitment of microglia during cuprizone-induced demyelination
    • PID: 23266461
    • Skripuletz T, Hackstette D, Bauer K, Gudi V, Pul R, Voss E et al (2013) Astrocytes regulate myelin clearance through recruitment of microglia during cuprizone-induced demyelination. Brain 136(Pt 1):147–167
    • (2013) Brain , vol.136 , pp. 147-167
    • Skripuletz, T.1    Hackstette, D.2    Bauer, K.3    Gudi, V.4    Pul, R.5    Voss, E.6
  • 135
    • 80455125893 scopus 로고    scopus 로고
    • Excess circulating alternatively activated myeloid (M2) cells accelerate ALS progression while inhibiting experimental autoimmune encephalomyelitis
    • PID: 22073221
    • Vaknin I, Kunis G, Miller O, Butovsky O, Bukshpan S, Beers DR et al (2011) Excess circulating alternatively activated myeloid (M2) cells accelerate ALS progression while inhibiting experimental autoimmune encephalomyelitis. PLoS One 6(11):e26921
    • (2011) PLoS One , vol.6 , Issue.11 , pp. e26921
    • Vaknin, I.1    Kunis, G.2    Miller, O.3    Butovsky, O.4    Bukshpan, S.5    Beers, D.R.6
  • 136
    • 0029972857 scopus 로고    scopus 로고
    • Brain microglia/macrophages express neurotrophins that selectively regulate microglial proliferation and function
    • Elkabes S, DiCicco-Bloom EM, Black IB (1996) Brain microglia/macrophages express neurotrophins that selectively regulate microglial proliferation and function. J Neurosci Off J Soc Neurosci 16(8):2508–2521
    • (1996) J Neurosci Off J Soc Neurosci , vol.16 , Issue.8 , pp. 2508-2521
    • Elkabes, S.1    DiCicco-Bloom, E.M.2    Black, I.B.3
  • 137
    • 84865022665 scopus 로고    scopus 로고
    • Regulation of postnatal forebrain amoeboid microglial cell proliferation and development by the transcription factor Runx1
    • Zusso M, Methot L, Lo R, Greenhalgh AD, David S, Stifani S (2012) Regulation of postnatal forebrain amoeboid microglial cell proliferation and development by the transcription factor Runx1. J Neurosci Off J Soc Neurosci 32(33):11285–11298
    • (2012) J Neurosci Off J Soc Neurosci , vol.32 , Issue.33 , pp. 11285-11298
    • Zusso, M.1    Methot, L.2    Lo, R.3    Greenhalgh, A.D.4    David, S.5    Stifani, S.6
  • 138
    • 0035152176 scopus 로고    scopus 로고
    • Regulation of Trk receptors following contusion of the rat spinal cord
    • PID: 11161589
    • Liebl DJ, Huang W, Young W, Parada LF (2001) Regulation of Trk receptors following contusion of the rat spinal cord. Exp Neurol 167(1):15–26
    • (2001) Exp Neurol , vol.167 , Issue.1 , pp. 15-26
    • Liebl, D.J.1    Huang, W.2    Young, W.3    Parada, L.F.4
  • 139
    • 45849151754 scopus 로고    scopus 로고
    • Peripherally-derived BDNF promotes regeneration of ascending sensory neurons after spinal cord injury
    • Song XY, Li F, Zhang FH, Zhong JH, Zhou XF (2013) Peripherally-derived BDNF promotes regeneration of ascending sensory neurons after spinal cord injury. PLoS One 3(3):e1707
    • (2013) PLoS One , vol.3 , Issue.3 , pp. e1707
    • Song, X.Y.1    Li, F.2    Zhang, F.H.3    Zhong, J.H.4    Zhou, X.F.5
  • 140
    • 84857624886 scopus 로고    scopus 로고
    • The effect of intrathecal administration of glial activation inhibitors on dorsal horn BDNF overexpression and hind paw mechanical allodynia in spinal nerve ligated rats
    • PID: 21901501
    • Zhang X, Xu Y, Wang J, Zhou Q, Pu S, Jiang W et al (2012) The effect of intrathecal administration of glial activation inhibitors on dorsal horn BDNF overexpression and hind paw mechanical allodynia in spinal nerve ligated rats. J Neural Transm 119(3):329–336
    • (2012) J Neural Transm , vol.119 , Issue.3 , pp. 329-336
    • Zhang, X.1    Xu, Y.2    Wang, J.3    Zhou, Q.4    Pu, S.5    Jiang, W.6
  • 141
    • 0034903476 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor (BDNF) is upregulated and associated with pain in chronic pancreatitis
    • PID: 11508661
    • Zhu ZW, Friess H, Wang L, Zimmermann A, Buchler MW (2001) Brain-derived neurotrophic factor (BDNF) is upregulated and associated with pain in chronic pancreatitis. Dig Dis Sci 46(8):1633–1639
    • (2001) Dig Dis Sci , vol.46 , Issue.8 , pp. 1633-1639
    • Zhu, Z.W.1    Friess, H.2    Wang, L.3    Zimmermann, A.4    Buchler, M.W.5
  • 142
    • 33847250395 scopus 로고    scopus 로고
    • Mouse and rat BDNF gene structure and expression revisited
    • PID: 17149751
    • Aid T, Kazantseva A, Piirsoo M, Palm K, Timmusk T (2007) Mouse and rat BDNF gene structure and expression revisited. J Neurosci Res 85(3):525–535
    • (2007) J Neurosci Res , vol.85 , Issue.3 , pp. 525-535
    • Aid, T.1    Kazantseva, A.2    Piirsoo, M.3    Palm, K.4    Timmusk, T.5
  • 143
    • 84857030341 scopus 로고    scopus 로고
    • Central nervous system rather than immune cell-derived BDNF mediates axonal protective effects early in autoimmune demyelination
    • PID: 22009304
    • Lee DH, Geyer E, Flach AC, Jung K, Gold R, Flugel A et al (2012) Central nervous system rather than immune cell-derived BDNF mediates axonal protective effects early in autoimmune demyelination. Acta Neuropathol 123(2):247–258
    • (2012) Acta Neuropathol , vol.123 , Issue.2 , pp. 247-258
    • Lee, D.H.1    Geyer, E.2    Flach, A.C.3    Jung, K.4    Gold, R.5    Flugel, A.6
  • 144
    • 0030711590 scopus 로고    scopus 로고
    • Reduced size of retinal ganglion cell axons and hypomyelination in mice lacking brain-derived neurotrophic factor
    • PID: 9361277
    • Cellerino A, Carroll P, Thoenen H, Barde Y-A (1997) Reduced size of retinal ganglion cell axons and hypomyelination in mice lacking brain-derived neurotrophic factor. Mol Cell Neurosci 9(5–6):397–408
    • (1997) Mol Cell Neurosci , vol.9 , Issue.5-6 , pp. 397-408
    • Cellerino, A.1    Carroll, P.2    Thoenen, H.3    Barde, Y.-A.4
  • 145
    • 19944433585 scopus 로고    scopus 로고
    • Effects of brain-derived neurotrophic factor (BDNF) on glial cells and serotonergic neurones during development
    • PID: 15659231
    • Djalali S, Holtje M, Grosse G, Rothe T, Stroh T, Grosse J et al (2005) Effects of brain-derived neurotrophic factor (BDNF) on glial cells and serotonergic neurones during development. J Neurochem 92(3):616–627
    • (2005) J Neurochem , vol.92 , Issue.3 , pp. 616-627
    • Djalali, S.1    Holtje, M.2    Grosse, G.3    Rothe, T.4    Stroh, T.5    Grosse, J.6
  • 146
    • 33845407240 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase pathway mediates effects of brain-derived neurotrophic factor on differentiation of basal forebrain oligodendrocytes
    • PID: 17044032
    • Du Y, Lercher LD, Zhou R, Dreyfus CF (2006) Mitogen-activated protein kinase pathway mediates effects of brain-derived neurotrophic factor on differentiation of basal forebrain oligodendrocytes. J Neurosci Res 84(8):1692–1702
    • (2006) J Neurosci Res , vol.84 , Issue.8 , pp. 1692-1702
    • Du, Y.1    Lercher, L.D.2    Zhou, R.3    Dreyfus, C.F.4
  • 147
    • 77649283854 scopus 로고    scopus 로고
    • Targeted retrograde gene delivery of brain-derived neurotrophic factor suppresses apoptosis of neurons and oligodendroglia after spinal cord injury in rats
    • PID: 20190624
    • Nakajima H, Uchida K, Yayama T, Kobayashi S, Guerrero AR, Furukawa S et al (2010) Targeted retrograde gene delivery of brain-derived neurotrophic factor suppresses apoptosis of neurons and oligodendroglia after spinal cord injury in rats. Spine 35(5):497–504
    • (2010) Spine , vol.35 , Issue.5 , pp. 497-504
    • Nakajima, H.1    Uchida, K.2    Yayama, T.3    Kobayashi, S.4    Guerrero, A.R.5    Furukawa, S.6
  • 148
    • 77957062260 scopus 로고    scopus 로고
    • Functional role of brain-derived neurotrophic factor in neuroprotective autoimmunity: therapeutic implications in a model of multiple sclerosis
    • PID: 20826430
    • Linker RA, Lee DH, Demir S, Wiese S, Kruse N, Siglienti I et al (2010) Functional role of brain-derived neurotrophic factor in neuroprotective autoimmunity: therapeutic implications in a model of multiple sclerosis. Brain 133(Pt 8):2248–2263
    • (2010) Brain , vol.133 , pp. 2248-2263
    • Linker, R.A.1    Lee, D.H.2    Demir, S.3    Wiese, S.4    Kruse, N.5    Siglienti, I.6
  • 149
    • 23044446572 scopus 로고    scopus 로고
    • Functional recovery in traumatic spinal cord injury after transplantation of multineurotrophin-expressing glial-restricted precursor cells
    • Cao Q, Xu XM, Devries WH, Enzmann GU, Ping P, Tsoulfas P et al (2005) Functional recovery in traumatic spinal cord injury after transplantation of multineurotrophin-expressing glial-restricted precursor cells. J Neurosci Off J Soc Neurosci 25(30):6947–6957
    • (2005) J Neurosci Off J Soc Neurosci , vol.25 , Issue.30 , pp. 6947-6957
    • Cao, Q.1    Xu, X.M.2    Devries, W.H.3    Enzmann, G.U.4    Ping, P.5    Tsoulfas, P.6
  • 150
    • 0033103608 scopus 로고    scopus 로고
    • Activated human T cells, B cells, and monocytes produce brain-derived neurotrophic factor in vitro and in inflammatory brain lesions: a neuroprotective role of inflammation?
    • PID: 10049950
    • Kerschensteiner M, Gallmeier E, Behrens L, Leal VV, Misgeld T, Klinkert WE et al (1999) Activated human T cells, B cells, and monocytes produce brain-derived neurotrophic factor in vitro and in inflammatory brain lesions: a neuroprotective role of inflammation? J Exp Med 189(5):865–870
    • (1999) J Exp Med , vol.189 , Issue.5 , pp. 865-870
    • Kerschensteiner, M.1    Gallmeier, E.2    Behrens, L.3    Leal, V.V.4    Misgeld, T.5    Klinkert, W.E.6
  • 151
    • 70349815768 scopus 로고    scopus 로고
    • Promoting oligodendrogenesis and myelin repair using the multiple sclerosis medication glatiramer acetate
    • PID: 19815532
    • Skihar V, Silva C, Chojnacki A, Doring A, Stallcup WB, Weiss S et al (2009) Promoting oligodendrogenesis and myelin repair using the multiple sclerosis medication glatiramer acetate. Proc Natl Acad Sci U S A 106(42):17992–17997
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.42 , pp. 17992-17997
    • Skihar, V.1    Silva, C.2    Chojnacki, A.3    Doring, A.4    Stallcup, W.B.5    Weiss, S.6
  • 152
    • 70449526305 scopus 로고    scopus 로고
    • Neuroprotection and neurogeneration in MS and its animal model EAE effected by glatiramer acetate
    • PID: 19669693
    • Arnon R, Aharoni R (2009) Neuroprotection and neurogeneration in MS and its animal model EAE effected by glatiramer acetate. J Neural Transm 116(11):1443–1449
    • (2009) J Neural Transm , vol.116 , Issue.11 , pp. 1443-1449
    • Arnon, R.1    Aharoni, R.2
  • 153
    • 79953890862 scopus 로고    scopus 로고
    • Glatiramer acetate in the treatment of multiple sclerosis: emerging concepts regarding its mechanism of action
    • PID: 21476611
    • Lalive PH, Neuhaus O, Benkhoucha M, Burger D, Hohlfeld R, Zamvil SS et al (2011) Glatiramer acetate in the treatment of multiple sclerosis: emerging concepts regarding its mechanism of action. CNS Drugs 25(5):401–414
    • (2011) CNS Drugs , vol.25 , Issue.5 , pp. 401-414
    • Lalive, P.H.1    Neuhaus, O.2    Benkhoucha, M.3    Burger, D.4    Hohlfeld, R.5    Zamvil, S.S.6
  • 154
    • 29444451569 scopus 로고    scopus 로고
    • Neurotrophic factors in relapsing remitting and secondary progressive multiple sclerosis patients during interferon beta therapy
    • PID: 16275091
    • Caggiula M, Batocchi AP, Frisullo G, Angelucci F, Patanella AK, Sancricca C et al (2006) Neurotrophic factors in relapsing remitting and secondary progressive multiple sclerosis patients during interferon beta therapy. Clin Immunol 118(1):77–82
    • (2006) Clin Immunol , vol.118 , Issue.1 , pp. 77-82
    • Caggiula, M.1    Batocchi, A.P.2    Frisullo, G.3    Angelucci, F.4    Patanella, A.K.5    Sancricca, C.6
  • 155
    • 79958007082 scopus 로고    scopus 로고
    • Recent insights into the mechanism of action of glatiramer acetate
    • PID: 21402415
    • Kala M, Miravalle A, Vollmer T (2011) Recent insights into the mechanism of action of glatiramer acetate. J Neuroimmunol 235(1–2):9–17
    • (2011) J Neuroimmunol , vol.235 , Issue.1-2 , pp. 9-17
    • Kala, M.1    Miravalle, A.2    Vollmer, T.3
  • 156
    • 79958770585 scopus 로고    scopus 로고
    • Insight into the mechanism of laquinimod action
    • PID: 21429524
    • Bruck W, Wegner C (2011) Insight into the mechanism of laquinimod action. J Neurol Sci 306(1–2):173–179
    • (2011) J Neurol Sci , vol.306 , Issue.1-2 , pp. 173-179
    • Bruck, W.1    Wegner, C.2
  • 157
    • 24144469398 scopus 로고    scopus 로고
    • Lower brain-derived neurotrophic factor in serum of relapsing remitting MS: reversal by glatiramer acetate
    • PID: 16083971
    • Azoulay D, Vachapova V, Shihman B, Miler A, Karni A (2005) Lower brain-derived neurotrophic factor in serum of relapsing remitting MS: reversal by glatiramer acetate. J Neuroimmunol 167(1–2):215–218
    • (2005) J Neuroimmunol , vol.167 , Issue.1-2 , pp. 215-218
    • Azoulay, D.1    Vachapova, V.2    Shihman, B.3    Miler, A.4    Karni, A.5
  • 159
    • 41949124799 scopus 로고    scopus 로고
    • Low and dysregulated BDNF secretion from immune cells of MS patients is related to reduced neuroprotection
    • PID: 18329726
    • Azoulay D, Urshansky N, Karni A (2008) Low and dysregulated BDNF secretion from immune cells of MS patients is related to reduced neuroprotection. J Neuroimmunol 195(1–2):186–193
    • (2008) J Neuroimmunol , vol.195 , Issue.1-2 , pp. 186-193
    • Azoulay, D.1    Urshansky, N.2    Karni, A.3
  • 160
    • 70350618216 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor and TrkB receptor in experimental autoimmune encephalomyelitis and multiple sclerosis
    • PID: 19758606
    • De Santi L, Annunziata P, Sessa E, Bramanti P (2009) Brain-derived neurotrophic factor and TrkB receptor in experimental autoimmune encephalomyelitis and multiple sclerosis. J Neurol Sci 287(1–2):17–26
    • (2009) J Neurol Sci , vol.287 , Issue.1-2 , pp. 17-26
    • De Santi, L.1    Annunziata, P.2    Sessa, E.3    Bramanti, P.4
  • 161
    • 67349175764 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor gene delivery in an animal model of multiple sclerosis using bone marrow stem cells as a vehicle
    • PID: 19361871
    • Makar TK, Bever CT, Singh IS, Royal W, Sahu SN, Sura TP (2009) Brain-derived neurotrophic factor gene delivery in an animal model of multiple sclerosis using bone marrow stem cells as a vehicle. J Neuroimmunol 210(1–2):40–51
    • (2009) J Neuroimmunol , vol.210 , Issue.1-2 , pp. 40-51
    • Makar, T.K.1    Bever, C.T.2    Singh, I.S.3    Royal, W.4    Sahu, S.N.5    Sura, T.P.6
  • 162
    • 0032528159 scopus 로고    scopus 로고
    • Neurotrophin-3 and brain-derived neurotrophic factor induce oligodendrocyte proliferation and myelination of regenerating axons in the contused adult Rat spinal cord
    • PID: 9651218
    • McTigue DM, Horner PJ, Stokes BT, Gage FH (1998) Neurotrophin-3 and brain-derived neurotrophic factor induce oligodendrocyte proliferation and myelination of regenerating axons in the contused adult Rat spinal cord. J Neurosci 18(14):5354–5365
    • (1998) J Neurosci , vol.18 , Issue.14 , pp. 5354-5365
    • McTigue, D.M.1    Horner, P.J.2    Stokes, B.T.3    Gage, F.H.4
  • 163
    • 30144445704 scopus 로고    scopus 로고
    • The effect of site and type of nerve injury on the expression of brain-derived neurotrophic factor in the dorsal root ganglion and on neuropathic pain behavior
    • PID: 16326015
    • Obata K, Yamanaka H, Kobayashi K, Dai Y, Mizushima T, Katsura H et al (2006) The effect of site and type of nerve injury on the expression of brain-derived neurotrophic factor in the dorsal root ganglion and on neuropathic pain behavior. Neuroscience 137(3):961–970
    • (2006) Neuroscience , vol.137 , Issue.3 , pp. 961-970
    • Obata, K.1    Yamanaka, H.2    Kobayashi, K.3    Dai, Y.4    Mizushima, T.5    Katsura, H.6
  • 164
    • 0034948264 scopus 로고    scopus 로고
    • Pegylated brain-derived neurotrophic factor shows improved distribution into the spinal cord and stimulates locomotor activity and morphological changes after injury
    • PID: 11421586
    • Ankeny DP, McTigue DM, Guan Z, Yan Q, Kinstler O, Stokes BT et al (2001) Pegylated brain-derived neurotrophic factor shows improved distribution into the spinal cord and stimulates locomotor activity and morphological changes after injury. Exp Neurol 170(1):85–100
    • (2001) Exp Neurol , vol.170 , Issue.1 , pp. 85-100
    • Ankeny, D.P.1    McTigue, D.M.2    Guan, Z.3    Yan, Q.4    Kinstler, O.5    Stokes, B.T.6
  • 165
    • 3042815957 scopus 로고    scopus 로고
    • Changes in galanin immunoreactivity in rat lumbosacral spinal cord and dorsal root ganglia after spinal cord injury
    • PID: 15236239
    • Zvarova K, Murray E, Vizzard MA (2004) Changes in galanin immunoreactivity in rat lumbosacral spinal cord and dorsal root ganglia after spinal cord injury. J Comp Neurol 475(4):590–603
    • (2004) J Comp Neurol , vol.475 , Issue.4 , pp. 590-603
    • Zvarova, K.1    Murray, E.2    Vizzard, M.A.3
  • 166
    • 33745112188 scopus 로고    scopus 로고
    • BDNF promotes connections of corticospinal neurons onto spared descending interneurons in spinal cord injured rats
    • PID: 16632552
    • Vavrek R, Girgis J, Tetzlaff W, Hiebert GW, Fouad K (2006) BDNF promotes connections of corticospinal neurons onto spared descending interneurons in spinal cord injured rats. Brain 129(Pt 6):1534–1545
    • (2006) Brain , vol.129 , pp. 1534-1545
    • Vavrek, R.1    Girgis, J.2    Tetzlaff, W.3    Hiebert, G.W.4    Fouad, K.5
  • 167
    • 43249120380 scopus 로고    scopus 로고
    • Myelin repair strategies: a cellular view
    • PID: 18451710
    • Gallo V, Armstrong RC (2008) Myelin repair strategies: a cellular view. Curr Opin Neurol 21(3):278–283
    • (2008) Curr Opin Neurol , vol.21 , Issue.3 , pp. 278-283
    • Gallo, V.1    Armstrong, R.C.2
  • 168
    • 84865538160 scopus 로고    scopus 로고
    • Fingolimod, a sphingosine-1 phosphate receptor modulator, increases BDNF levels and improves symptoms of a mouse model of Rett syndrome
    • PID: 22891354
    • Deogracias R, Yazdani M, Dekkers MP, Guy J, Ionescu MC, Vogt KE et al (2012) Fingolimod, a sphingosine-1 phosphate receptor modulator, increases BDNF levels and improves symptoms of a mouse model of Rett syndrome. Proc Natl Acad Sci U S A 109(35):14230–14235
    • (2012) Proc Natl Acad Sci U S A , vol.109 , Issue.35 , pp. 14230-14235
    • Deogracias, R.1    Yazdani, M.2    Dekkers, M.P.3    Guy, J.4    Ionescu, M.C.5    Vogt, K.E.6
  • 169
    • 0036845819 scopus 로고    scopus 로고
    • Glatiramer acetate-specific T-helper 1- and 2-type cell lines produce BDNF: implications for multiple sclerosis therapy. Brain-derived neurotrophic factor
    • PID: 12390966
    • Ziemssen T, Kumpfel T, Klinkert WE, Neuhaus O, Hohlfeld R (2002) Glatiramer acetate-specific T-helper 1- and 2-type cell lines produce BDNF: implications for multiple sclerosis therapy. Brain-derived neurotrophic factor. Brain 125(Pt 11):2381–2391
    • (2002) Brain , vol.125 , pp. 2381-2391
    • Ziemssen, T.1    Kumpfel, T.2    Klinkert, W.E.3    Neuhaus, O.4    Hohlfeld, R.5
  • 170
    • 30044451754 scopus 로고    scopus 로고
    • The immunomodulator glatiramer acetate augments the expression of neurotrophic factors in brains of experimental autoimmune encephalomyelitis mice
    • PID: 16365293
    • Aharoni R, Eilam R, Domev H, Labunskay G, Sela M, Arnon R (2005) The immunomodulator glatiramer acetate augments the expression of neurotrophic factors in brains of experimental autoimmune encephalomyelitis mice. Proc Natl Acad Sci U S A 102(52):19045–19050
    • (2005) Proc Natl Acad Sci U S A , vol.102 , Issue.52 , pp. 19045-19050
    • Aharoni, R.1    Eilam, R.2    Domev, H.3    Labunskay, G.4    Sela, M.5    Arnon, R.6
  • 171
    • 0142074862 scopus 로고    scopus 로고
    • Glatiramer acetate-reactive T cells produce brain-derived neurotrophic factor
    • PID: 14568126
    • Chen M, Valenzuela RM, Dhib-Jalbut S (2003) Glatiramer acetate-reactive T cells produce brain-derived neurotrophic factor. J Neurol Sci 215(1–2):37–44
    • (2003) J Neurol Sci , vol.215 , Issue.1-2 , pp. 37-44
    • Chen, M.1    Valenzuela, R.M.2    Dhib-Jalbut, S.3
  • 172
    • 78651088248 scopus 로고    scopus 로고
    • Glatiramer acetate (GA, Copolymer-1) an hypothetical treatment option for Rett syndrome
    • PID: 20951500
    • Ben-Zeev B, Aharoni R, Nissenkorn A, Arnon R (2011) Glatiramer acetate (GA, Copolymer-1) an hypothetical treatment option for Rett syndrome. Med Hypotheses 76(2):190–193
    • (2011) Med Hypotheses , vol.76 , Issue.2 , pp. 190-193
    • Ben-Zeev, B.1    Aharoni, R.2    Nissenkorn, A.3    Arnon, R.4
  • 173
    • 83555174399 scopus 로고    scopus 로고
    • Modulation of autoimmune demyelination by laquinimod via induction of brain-derived neurotrophic factor
    • PID: 22152994
    • Thone J, Ellrichmann G, Seubert S, Peruga I, Lee DH, Conrad R et al (2012) Modulation of autoimmune demyelination by laquinimod via induction of brain-derived neurotrophic factor. Am J Path 180(1):267–274
    • (2012) Am J Path , vol.180 , Issue.1 , pp. 267-274
    • Thone, J.1    Ellrichmann, G.2    Seubert, S.3    Peruga, I.4    Lee, D.H.5    Conrad, R.6
  • 174
    • 45249107267 scopus 로고    scopus 로고
    • Effect of laquinimod on MRI-monitored disease activity in patients with relapsing-remitting multiple sclerosis: a multicentre, randomised, double-blind, placebo-controlled phase IIb study
    • PID: 18572078
    • Comi G, Pulizzi A, Rovaris M, Abramsky O, Arbizu T, Boiko A et al (2008) Effect of laquinimod on MRI-monitored disease activity in patients with relapsing-remitting multiple sclerosis: a multicentre, randomised, double-blind, placebo-controlled phase IIb study. Lancet 371(9630):2085–2092
    • (2008) Lancet , vol.371 , Issue.9630 , pp. 2085-2092
    • Comi, G.1    Pulizzi, A.2    Rovaris, M.3    Abramsky, O.4    Arbizu, T.5    Boiko, A.6
  • 175
    • 35148840586 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor expression and respiratory function improve after ampakine treatment in a mouse model of Rett syndrome
    • Ogier M, Wang H, Hong E, Wang Q, Greenberg ME, Katz DM (2007) Brain-derived neurotrophic factor expression and respiratory function improve after ampakine treatment in a mouse model of Rett syndrome. J Neurosci Off J Soc Neurosci 27(40):10912–10917
    • (2007) J Neurosci Off J Soc Neurosci , vol.27 , Issue.40 , pp. 10912-10917
    • Ogier, M.1    Wang, H.2    Hong, E.3    Wang, Q.4    Greenberg, M.E.5    Katz, D.M.6
  • 176
    • 33750941251 scopus 로고    scopus 로고
    • Dysregulation of brain-derived neurotrophic factor expression and neurosecretory function in Mecp2 null mice
    • Wang H, Chan SA, Ogier M, Hellard D, Wang Q, Smith C et al (2006) Dysregulation of brain-derived neurotrophic factor expression and neurosecretory function in Mecp2 null mice. J Neurosci Off J Soc Neurosci 26(42):10911–10915
    • (2006) J Neurosci Off J Soc Neurosci , vol.26 , Issue.42 , pp. 10911-10915
    • Wang, H.1    Chan, S.A.2    Ogier, M.3    Hellard, D.4    Wang, Q.5    Smith, C.6
  • 177
    • 52049126415 scopus 로고    scopus 로고
    • Deletion of Mecp2 in Sim1-expressing neurons reveals a critical role for MeCP2 in feeding behavior, aggression, and the response to stress
    • PID: 18817733
    • Fyffe SL, Neul JL, Samaco RC, Chao HT, Ben-Shachar S, Moretti P et al (2008) Deletion of Mecp2 in Sim1-expressing neurons reveals a critical role for MeCP2 in feeding behavior, aggression, and the response to stress. Neuron 59(6):947–958
    • (2008) Neuron , vol.59 , Issue.6 , pp. 947-958
    • Fyffe, S.L.1    Neul, J.L.2    Samaco, R.C.3    Chao, H.T.4    Ben-Shachar, S.5    Moretti, P.6
  • 178
    • 34247170462 scopus 로고    scopus 로고
    • FXYD1 is an MeCP2 target gene overexpressed in the brains of Rett syndrome patients and Mecp2-null mice
    • PID: 17309881
    • Deng V, Matagne V, Banine F, Frerking M, Ohliger P, Budden S et al (2007) FXYD1 is an MeCP2 target gene overexpressed in the brains of Rett syndrome patients and Mecp2-null mice. Hum Mol Genet 16(6):640–650
    • (2007) Hum Mol Genet , vol.16 , Issue.6 , pp. 640-650
    • Deng, V.1    Matagne, V.2    Banine, F.3    Frerking, M.4    Ohliger, P.5    Budden, S.6
  • 179
    • 77951014800 scopus 로고    scopus 로고
    • Exogenous brain-derived neurotrophic factor rescues synaptic dysfunction in Mecp2-null mice
    • Kline DD, Ogier M, Kunze DL, Katz DM (2010) Exogenous brain-derived neurotrophic factor rescues synaptic dysfunction in Mecp2-null mice. J Neurosci Off J Soc Neurosci 30(15):5303–5310
    • (2010) J Neurosci Off J Soc Neurosci , vol.30 , Issue.15 , pp. 5303-5310
    • Kline, D.D.1    Ogier, M.2    Kunze, D.L.3    Katz, D.M.4
  • 180
    • 84863025204 scopus 로고    scopus 로고
    • A TrkB small molecule partial agonist rescues TrkB phosphorylation deficits and improves respiratory function in a mouse model of Rett syndrome
    • Schmid DA, Yang T, Ogier M, Adams I, Mirakhur Y, Wang Q et al (2012) A TrkB small molecule partial agonist rescues TrkB phosphorylation deficits and improves respiratory function in a mouse model of Rett syndrome. J Neurosci Off J Soc Neurosci 32(5):1803–1810
    • (2012) J Neurosci Off J Soc Neurosci , vol.32 , Issue.5 , pp. 1803-1810
    • Schmid, D.A.1    Yang, T.2    Ogier, M.3    Adams, I.4    Mirakhur, Y.5    Wang, Q.6
  • 181
    • 84907192606 scopus 로고    scopus 로고
    • A BDNF loop-domain mimetic acutely reverses spontaneous apneas and respiratory abnormalities during behavioral arousal in a mouse model of Rett syndrome
    • PID: 25147297
    • Kron M, Lang M, Adams IT, Sceniak M, Longo F, Katz DM (2014) A BDNF loop-domain mimetic acutely reverses spontaneous apneas and respiratory abnormalities during behavioral arousal in a mouse model of Rett syndrome. Dis Model Mech 7(9):1047–1055
    • (2014) Dis Model Mech , vol.7 , Issue.9 , pp. 1047-1055
    • Kron, M.1    Lang, M.2    Adams, I.T.3    Sceniak, M.4    Longo, F.5    Katz, D.M.6
  • 182
    • 39749193120 scopus 로고    scopus 로고
    • MeCP2 deficiency in the brain decreases BDNF levels by REST/CoREST-mediated repression and increases TRKB production
    • Abuhatzira L, Makedonski K, Kaufman Y, Razin A, Shemer R (2007) MeCP2 deficiency in the brain decreases BDNF levels by REST/CoREST-mediated repression and increases TRKB production. Epigenetics 29:2(4)
    • (2007) Epigenetics , vol.29 , pp. 2(4)
    • Abuhatzira, L.1    Makedonski, K.2    Kaufman, Y.3    Razin, A.4    Shemer, R.5
  • 185
    • 79951571473 scopus 로고    scopus 로고
    • Role of HDAC3 on p53 expression and apoptosis in T cells of patients with multiple sclerosis
    • PID: 21346816
    • Zhang F, Shi Y, Wang L, Sriram S (2011) Role of HDAC3 on p53 expression and apoptosis in T cells of patients with multiple sclerosis. PLoS One 6(2):e16795
    • (2011) PLoS One , vol.6 , Issue.2 , pp. e16795
    • Zhang, F.1    Shi, Y.2    Wang, L.3    Sriram, S.4
  • 186
    • 80053574021 scopus 로고    scopus 로고
    • Treatment of brain inflammatory diseases by delivering exosome encapsulated anti-inflammatory drugs from the nasal region to the brain
    • Zhuang X, Xiang X, Grizzle W, Sun D, Zhang S, Axtell RC et al (2011) Treatment of brain inflammatory diseases by delivering exosome encapsulated anti-inflammatory drugs from the nasal region to the brain. Mol Ther J Am Soc Gene Ther 19(10):1769–1779
    • (2011) Mol Ther J Am Soc Gene Ther , vol.19 , Issue.10 , pp. 1769-1779
    • Zhuang, X.1    Xiang, X.2    Grizzle, W.3    Sun, D.4    Zhang, S.5    Axtell, R.C.6
  • 187
    • 20444484556 scopus 로고    scopus 로고
    • Oral flavonoids delay recovery from experimental autoimmune encephalomyelitis in SJL mice
    • PID: 15946653
    • Verbeek R, van Tol EA, van Noort JM (2005) Oral flavonoids delay recovery from experimental autoimmune encephalomyelitis in SJL mice. Biochem Pharmacol 70(2):220–228
    • (2005) Biochem Pharmacol , vol.70 , Issue.2 , pp. 220-228
    • Verbeek, R.1    van Tol, E.A.2    van Noort, J.M.3
  • 188
    • 0347296187 scopus 로고    scopus 로고
    • Sodium phenylacetate inhibits adoptive transfer of experimental allergic encephalomyelitis in SJL/J mice at multiple steps
    • PID: 12646656
    • Dasgupta S, Zhou Y, Jana M, Banik NL, Pahan K (2003) Sodium phenylacetate inhibits adoptive transfer of experimental allergic encephalomyelitis in SJL/J mice at multiple steps. J Immunol 170(7):3874–3882
    • (2003) J Immunol , vol.170 , Issue.7 , pp. 3874-3882
    • Dasgupta, S.1    Zhou, Y.2    Jana, M.3    Banik, N.L.4    Pahan, K.5
  • 189
    • 38449114350 scopus 로고    scopus 로고
    • Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A
    • Yoshida M (2007) Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A. Tanpakushitsu Kakusan Koso Protein Nucleic Acid Enzym 52(13 Suppl):1788–1789
    • (2007) Tanpakushitsu Kakusan Koso Protein Nucleic Acid Enzym , vol.52 , pp. 1788-1789
    • Yoshida, M.1
  • 190
    • 0042922772 scopus 로고    scopus 로고
    • Insulin-like growth factor (IGF) signaling through type 1 IGF receptor plays an important role in remyelination
    • Mason JL, Xuan S, Dragatsis I, Efstratiadis A, Goldman JE (2003) Insulin-like growth factor (IGF) signaling through type 1 IGF receptor plays an important role in remyelination. J Neurosci Off J Soc Neurosci 23(20):7710–7718
    • (2003) J Neurosci Off J Soc Neurosci , vol.23 , Issue.20 , pp. 7710-7718
    • Mason, J.L.1    Xuan, S.2    Dragatsis, I.3    Efstratiadis, A.4    Goldman, J.E.5
  • 191
    • 0032577868 scopus 로고    scopus 로고
    • Differential expression of human histone deacetylase mRNAs in response to immune cell apoptosis induction by trichostatin A and butyrate
    • PID: 9647779
    • Dangond F, Gullans SR (1998) Differential expression of human histone deacetylase mRNAs in response to immune cell apoptosis induction by trichostatin A and butyrate. Biochem Biophys Res Commun 247(3):833–837
    • (1998) Biochem Biophys Res Commun , vol.247 , Issue.3 , pp. 833-837
    • Dangond, F.1    Gullans, S.R.2
  • 192
    • 0038408486 scopus 로고    scopus 로고
    • Histone deacetylase inhibitor up-regulates RECK to inhibit MMP-2 activation and cancer cell invasion
    • PID: 12810630
    • Liu LT, Chang HC, Chiang LC, Hung WC (2003) Histone deacetylase inhibitor up-regulates RECK to inhibit MMP-2 activation and cancer cell invasion. Cancer Res 63(12):3069–3072
    • (2003) Cancer Res , vol.63 , Issue.12 , pp. 3069-3072
    • Liu, L.T.1    Chang, H.C.2    Chiang, L.C.3    Hung, W.C.4
  • 193
    • 0029889674 scopus 로고    scopus 로고
    • Effect of steroids on CSF matrix metalloproteinases in multiple sclerosis: relation to blood–brain barrier injury
    • PID: 8649561
    • Rosenberg GA, Dencoff JE, Correa N Jr, Reiners M, Ford CC (1996) Effect of steroids on CSF matrix metalloproteinases in multiple sclerosis: relation to blood–brain barrier injury. Neurology 46(6):1626–1632
    • (1996) Neurology , vol.46 , Issue.6 , pp. 1626-1632
    • Rosenberg, G.A.1    Dencoff, J.E.2    Correa, N.3    Reiners, M.4    Ford, C.C.5
  • 194
    • 84877057244 scopus 로고    scopus 로고
    • Epigenetic silencing of the proapoptotic gene BIM in anaplastic large cell lymphoma through an MeCP2/SIN3a deacetylating complex
    • PID: 23633923
    • Piazza R, Magistroni V, Mogavero A, Andreoni F, Ambrogio C, Chiarle R et al (2013) Epigenetic silencing of the proapoptotic gene BIM in anaplastic large cell lymphoma through an MeCP2/SIN3a deacetylating complex. Neoplasia 15(5):511–522
    • (2013) Neoplasia , vol.15 , Issue.5 , pp. 511-522
    • Piazza, R.1    Magistroni, V.2    Mogavero, A.3    Andreoni, F.4    Ambrogio, C.5    Chiarle, R.6
  • 195
    • 77955709610 scopus 로고    scopus 로고
    • HDAC inhibition promotes neuronal outgrowth and counteracts growth cone collapse through CBP/p300 and P/CAF-dependent p53 acetylation
    • PID: 20094059
    • Gaub P, Tedeschi A, Puttagunta R, Nguyen T, Schmandke A, Di Giovanni S (2010) HDAC inhibition promotes neuronal outgrowth and counteracts growth cone collapse through CBP/p300 and P/CAF-dependent p53 acetylation. Cell Death Differ 17(9):1392–1408
    • (2010) Cell Death Differ , vol.17 , Issue.9 , pp. 1392-1408
    • Gaub, P.1    Tedeschi, A.2    Puttagunta, R.3    Nguyen, T.4    Schmandke, A.5    Di Giovanni, S.6
  • 196
    • 84901001266 scopus 로고    scopus 로고
    • HDAC inhibitors mitigate ischemia-induced oligodendrocyte damage: potential roles of oligodendrogenesis, VEGF, and anti-inflammation
    • PID: 24936215
    • Kim HJ, Chuang DM (2014) HDAC inhibitors mitigate ischemia-induced oligodendrocyte damage: potential roles of oligodendrogenesis, VEGF, and anti-inflammation. Am J Transl Res 6(3):206–223
    • (2014) Am J Transl Res , vol.6 , Issue.3 , pp. 206-223
    • Kim, H.J.1    Chuang, D.M.2
  • 197
    • 34447130226 scopus 로고    scopus 로고
    • The glial or neuronal fate choice of oligodendrocyte progenitors is modulated by their ability to acquire an epigenetic memory
    • Liu A, Han YR, Li J, Sun D, Ouyang M, Plummer MR et al (2007) The glial or neuronal fate choice of oligodendrocyte progenitors is modulated by their ability to acquire an epigenetic memory. J Neurosci Off J Soc Neurosci 27(27):7339–7343
    • (2007) J Neurosci Off J Soc Neurosci , vol.27 , Issue.27 , pp. 7339-7343
    • Liu, A.1    Han, Y.R.2    Li, J.3    Sun, D.4    Ouyang, M.5    Plummer, M.R.6
  • 198
    • 35448949103 scopus 로고    scopus 로고
    • Inhibition of histone deacetylase activity induces developmental plasticity in oligodendrocyte precursor cells
    • PID: 17855562
    • Lyssiotis CA, Walker J, Wu C, Kondo T, Schultz PG, Wu X (2007) Inhibition of histone deacetylase activity induces developmental plasticity in oligodendrocyte precursor cells. Proc Natl Acad Sci U S A 104(38):14982–14987
    • (2007) Proc Natl Acad Sci U S A , vol.104 , Issue.38 , pp. 14982-14987
    • Lyssiotis, C.A.1    Walker, J.2    Wu, C.3    Kondo, T.4    Schultz, P.G.5    Wu, X.6
  • 199
    • 83555164704 scopus 로고    scopus 로고
    • Epigenetic CpG demethylation of the promoter and reactivation of the expression of Neurog1 by curcumin in prostate LNCaP cells
    • PID: 21938566
    • Shu L, Khor TO, Lee JH, Boyanapalli SS, Huang Y, Wu TY et al (2011) Epigenetic CpG demethylation of the promoter and reactivation of the expression of Neurog1 by curcumin in prostate LNCaP cells. AAPS J 13(4):606–614
    • (2011) AAPS J , vol.13 , Issue.4 , pp. 606-614
    • Shu, L.1    Khor, T.O.2    Lee, J.H.3    Boyanapalli, S.S.4    Huang, Y.5    Wu, T.Y.6
  • 200
    • 0000907007 scopus 로고    scopus 로고
    • Valle DBA, Vogelstein B, Kinzler KW, Antonarakis SE, Ballabio A, Gibson K, Mitchell G, (eds), McGraw-Hill, New York
    • Lupski GC Jr (2001) In: Valle DBA, Vogelstein B, Kinzler KW, Antonarakis SE, Ballabio A, Gibson K, Mitchell G (eds) Charcot-Marie-tooth peripheral neuropathies and related disorders. McGraw-Hill, New York
    • (2001) Charcot-Marie-tooth peripheral neuropathies and related disorders
    • Lupski, G.C.1
  • 201
    • 34548219064 scopus 로고    scopus 로고
    • Oral curcumin mitigates the clinical and neuropathologic phenotype of the Trembler-J mouse: a potential therapy for inherited neuropathy
    • PID: 17701891
    • Khajavi M, Shiga K, Wiszniewski W, He F, Shaw CA, Yan J et al (2007) Oral curcumin mitigates the clinical and neuropathologic phenotype of the Trembler-J mouse: a potential therapy for inherited neuropathy. Am J Hum Genet 81(3):438–453
    • (2007) Am J Hum Genet , vol.81 , Issue.3 , pp. 438-453
    • Khajavi, M.1    Shiga, K.2    Wiszniewski, W.3    He, F.4    Shaw, C.A.5    Yan, J.6
  • 202
    • 84871760898 scopus 로고    scopus 로고
    • Curcumin derivatives promote Schwann cell differentiation and improve neuropathy in R98C CMT1B mice
    • PID: 23250879
    • Patzko A, Bai Y, Saporta MA, Katona I, Wu X, Vizzuso D et al (2012) Curcumin derivatives promote Schwann cell differentiation and improve neuropathy in R98C CMT1B mice. Brain 135(Pt 12):3551–3566
    • (2012) Brain , vol.135 , pp. 3551-3566
    • Patzko, A.1    Bai, Y.2    Saporta, M.A.3    Katona, I.4    Wu, X.5    Vizzuso, D.6
  • 203
    • 84926158796 scopus 로고    scopus 로고
    • Curcumin induced up-regulation of Myelin basic protein (MBP) ameliorates sodium arsenite induced neurotoxicity in developing rat cerebellum
    • Kaushala P, Mehra RD, Dharc P (2014) Curcumin induced up-regulation of Myelin basic protein (MBP) ameliorates sodium arsenite induced neurotoxicity in developing rat cerebellum. J Anat Soc India 63(1):3–11
    • (2014) J Anat Soc India , vol.63 , Issue.1 , pp. 3-11
    • Kaushala, P.1    Mehra, R.D.2    Dharc, P.3
  • 204
    • 79953775516 scopus 로고    scopus 로고
    • White matter lesions in Parkinson disease
    • PID: 21343896
    • Bohnen NI, Albin RL (2011) White matter lesions in Parkinson disease. Nat Rev Neurol 7(4):229–236
    • (2011) Nat Rev Neurol , vol.7 , Issue.4 , pp. 229-236
    • Bohnen, N.I.1    Albin, R.L.2
  • 206
    • 84864930304 scopus 로고    scopus 로고
    • White matter network abnormalities are associated with cognitive decline in chronic epilepsy
    • PID: 22038907
    • Vaessen MJ, Jansen JF, Vlooswijk MC, Hofman PA, Majoie HJ, Aldenkamp AP et al (2012) White matter network abnormalities are associated with cognitive decline in chronic epilepsy. Cereb Cortex 22(9):2139–2147
    • (2012) Cereb Cortex , vol.22 , Issue.9 , pp. 2139-2147
    • Vaessen, M.J.1    Jansen, J.F.2    Vlooswijk, M.C.3    Hofman, P.A.4    Majoie, H.J.5    Aldenkamp, A.P.6
  • 207
    • 34648846215 scopus 로고    scopus 로고
    • Cerebral cortical and white matter lesions in amyotrophic lateral sclerosis with dementia: correlation with MR and pathologic examinations
    • PID: 17846201
    • Matsusue E, Sugihara S, Fujii S, Kinoshita T, Nakano T, Ohama E et al (2007) Cerebral cortical and white matter lesions in amyotrophic lateral sclerosis with dementia: correlation with MR and pathologic examinations. AJNR Am J Neuroradiol 28(8):1505–1510
    • (2007) AJNR Am J Neuroradiol , vol.28 , Issue.8 , pp. 1505-1510
    • Matsusue, E.1    Sugihara, S.2    Fujii, S.3    Kinoshita, T.4    Nakano, T.5    Ohama, E.6
  • 208
    • 28944434037 scopus 로고    scopus 로고
    • White matter lesions are prevalent but differentially related with cognition in aging and early Alzheimer disease
    • PID: 16344345
    • Burns JM, Church JA, Johnson DK, Xiong C, Marcus D, Fotenos AF et al (2005) White matter lesions are prevalent but differentially related with cognition in aging and early Alzheimer disease. Arch Neurol 62(12):1870–1876
    • (2005) Arch Neurol , vol.62 , Issue.12 , pp. 1870-1876
    • Burns, J.M.1    Church, J.A.2    Johnson, D.K.3    Xiong, C.4    Marcus, D.5    Fotenos, A.F.6
  • 209
    • 46349108931 scopus 로고    scopus 로고
    • Characterizing white matter damage in rat spinal cord with quantitative MRI and histology
    • PID: 18578635
    • Kozlowski P, Raj D, Liu J, Lam C, Yung AC, Tetzlaff W (2008) Characterizing white matter damage in rat spinal cord with quantitative MRI and histology. J Neurotrauma 25(6):653–676
    • (2008) J Neurotrauma , vol.25 , Issue.6 , pp. 653-676
    • Kozlowski, P.1    Raj, D.2    Liu, J.3    Lam, C.4    Yung, A.C.5    Tetzlaff, W.6
  • 210
    • 4444260120 scopus 로고    scopus 로고
    • BDNF overexpression produces a long-term increase in myelin formation in the peripheral nervous system
    • PID: 15352212
    • Tolwani RJ, Cosgaya JM, Varma S, Jacob R, Kuo LE, Shooter EM (2004) BDNF overexpression produces a long-term increase in myelin formation in the peripheral nervous system. J Neurosci Res 77(5):662–669
    • (2004) J Neurosci Res , vol.77 , Issue.5 , pp. 662-669
    • Tolwani, R.J.1    Cosgaya, J.M.2    Varma, S.3    Jacob, R.4    Kuo, L.E.5    Shooter, E.M.6
  • 211
    • 32244442040 scopus 로고    scopus 로고
    • Distinct effects of p75 in mediating actions of neurotrophins on basal forebrain oligodendrocytes
    • PID: 16356734
    • Du Y, Fischer TZ, Clinton-Luke P, Lercher LD, Dreyfus CF (2006) Distinct effects of p75 in mediating actions of neurotrophins on basal forebrain oligodendrocytes. Mol Cell Neurosci 31(2):366–375
    • (2006) Mol Cell Neurosci , vol.31 , Issue.2 , pp. 366-375
    • Du, Y.1    Fischer, T.Z.2    Clinton-Luke, P.3    Lercher, L.D.4    Dreyfus, C.F.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.