메뉴 건너뛰기




Volumn 23, Issue 11, 2012, Pages 1498-1507

Differential regulation of CD4+ T helper cell responses by curcumin in experimental autoimmune encephalomyelitis

Author keywords

Autoimmune disease; Curcumin; EAE MS; Inflammation; Nutraceuticals; Th1 cell

Indexed keywords

CURCUMIN; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 17; INTERLEUKIN 23; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TRANSCRIPTION FACTOR FOXP3;

EID: 84867719585     PISSN: 09552863     EISSN: 18734847     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2011.10.002     Document Type: Article
Times cited : (79)

References (48)
  • 1
    • 0034117911 scopus 로고    scopus 로고
    • Traditional Indian systems of medicine
    • Lodha R., Bagga A. Traditional Indian systems of medicine. Ann Acad Med Singapore 2000, 29:37-41.
    • (2000) Ann Acad Med Singapore , vol.29 , pp. 37-41
    • Lodha, R.1    Bagga, A.2
  • 2
    • 0015785965 scopus 로고
    • Pharmacology of diferuloyl methane (curcumin), a non-steroidal anti-inflammatory agent
    • Srimal R.C., Dhawan B.N. Pharmacology of diferuloyl methane (curcumin), a non-steroidal anti-inflammatory agent. J Pharm Pharmacol 1973, 25:447-452.
    • (1973) J Pharm Pharmacol , vol.25 , pp. 447-452
    • Srimal, R.C.1    Dhawan, B.N.2
  • 3
    • 0035404019 scopus 로고    scopus 로고
    • Biological activities of Curcuma longa L
    • Araujo C.C., Leon L.L. Biological activities of Curcuma longa L. Mem Inst Oswaldo Cruz 2001, 96:723-728.
    • (2001) Mem Inst Oswaldo Cruz , vol.96 , pp. 723-728
    • Araujo, C.C.1    Leon, L.L.2
  • 4
    • 0027519772 scopus 로고
    • Three non-phenolic diarylheptanoids with anti-inflammatory activity from Curcuma xanthorrhiza
    • Claeson P., Panthong A., Tuchinda P., Reutrakul V., Kanjanapothi D., Taylor W.C., et al. Three non-phenolic diarylheptanoids with anti-inflammatory activity from Curcuma xanthorrhiza. Planta Med 1993, 59:451-454.
    • (1993) Planta Med , vol.59 , pp. 451-454
    • Claeson, P.1    Panthong, A.2    Tuchinda, P.3    Reutrakul, V.4    Kanjanapothi, D.5    Taylor, W.C.6
  • 5
    • 0020450453 scopus 로고
    • Anti-inflammatory and irritant activities of curcumin analogues in rats
    • Mukhopadhyay A., Basu N., Ghatak N., Gujral P.K. Anti-inflammatory and irritant activities of curcumin analogues in rats. Agents Actions 1982, 12:508-515.
    • (1982) Agents Actions , vol.12 , pp. 508-515
    • Mukhopadhyay, A.1    Basu, N.2    Ghatak, N.3    Gujral, P.K.4
  • 6
    • 0032813348 scopus 로고    scopus 로고
    • Molecular mechanisms of chemopreventive effects of selected dietary and medicinal phenolic substances
    • Surh Y. Molecular mechanisms of chemopreventive effects of selected dietary and medicinal phenolic substances. Mutat Res 1999, 428:305-327.
    • (1999) Mutat Res , vol.428 , pp. 305-327
    • Surh, Y.1
  • 7
    • 0028587702 scopus 로고
    • Curcuminoids as potent inhibitors of lipid peroxidation
    • Sreejayan, Rao M.N. Curcuminoids as potent inhibitors of lipid peroxidation. J Pharm Pharmacol 1994, 46:1013-1016.
    • (1994) J Pharm Pharmacol , vol.46 , pp. 1013-1016
    • SreejayanRao, M.N.1
  • 8
    • 0032525741 scopus 로고    scopus 로고
    • In vivo inhibition of nitric oxide synthase gene expression by curcumin, a cancer preventive natural product with anti-inflammatory properties
    • Chan M.M., Huang H.I., Fenton M.R., Fong D. In vivo inhibition of nitric oxide synthase gene expression by curcumin, a cancer preventive natural product with anti-inflammatory properties. Biochem Pharmacol 1998, 55:1955-1962.
    • (1998) Biochem Pharmacol , vol.55 , pp. 1955-1962
    • Chan, M.M.1    Huang, H.I.2    Fenton, M.R.3    Fong, D.4
  • 9
    • 0028043644 scopus 로고
    • Curcumin inhibits TPA induced expression of c-fos, c-jun and c-myc proto-oncogenes messenger RNAs in mouse skin
    • Kakar S.S., Roy D. Curcumin inhibits TPA induced expression of c-fos, c-jun and c-myc proto-oncogenes messenger RNAs in mouse skin. Cancer Lett 1994, 87:85-89.
    • (1994) Cancer Lett , vol.87 , pp. 85-89
    • Kakar, S.S.1    Roy, D.2
  • 10
    • 0035451363 scopus 로고    scopus 로고
    • Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: down-regulation of COX-2 and iNOS through suppression of NF-kappa B activation
    • Surh Y.J., Chun K.S., Cha H.H., Han S.S., Keum Y.S., Park K.K., et al. Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: down-regulation of COX-2 and iNOS through suppression of NF-kappa B activation. Mutat Res 2001, 480-481:243-268.
    • (2001) Mutat Res , vol.480-481 , pp. 243-268
    • Surh, Y.J.1    Chun, K.S.2    Cha, H.H.3    Han, S.S.4    Keum, Y.S.5    Park, K.K.6
  • 11
    • 0033429405 scopus 로고    scopus 로고
    • Inhibition of interleukin-12 production in lipopolysaccharide-activated macrophages by curcumin
    • Kang B.Y., Chung S.W., Chung W., Im S., Hwang S.Y., Kim T.S. Inhibition of interleukin-12 production in lipopolysaccharide-activated macrophages by curcumin. Eur J Pharmacol 1999, 384:191-195.
    • (1999) Eur J Pharmacol , vol.384 , pp. 191-195
    • Kang, B.Y.1    Chung, S.W.2    Chung, W.3    Im, S.4    Hwang, S.Y.5    Kim, T.S.6
  • 12
    • 0032883350 scopus 로고    scopus 로고
    • Curcumin inhibits Th1 cytokine profile in CD4+ T cells by suppressing interleukin-12 production in macrophages
    • Kang B.Y., Song Y.J., Kim K.M., Choe Y.K., Hwang S.Y., Kim T.S. Curcumin inhibits Th1 cytokine profile in CD4+ T cells by suppressing interleukin-12 production in macrophages. Br J Pharmacol 1999, 128:380-384.
    • (1999) Br J Pharmacol , vol.128 , pp. 380-384
    • Kang, B.Y.1    Song, Y.J.2    Kim, K.M.3    Choe, Y.K.4    Hwang, S.Y.5    Kim, T.S.6
  • 13
    • 0033988511 scopus 로고    scopus 로고
    • Drugs in development for the treatment of multiple sclerosis: antigen non-specific therapies-an update
    • Donoghue S., Greenlees C. Drugs in development for the treatment of multiple sclerosis: antigen non-specific therapies-an update. Expert Opin Investig Drugs 2000, 9:167-171.
    • (2000) Expert Opin Investig Drugs , vol.9 , pp. 167-171
    • Donoghue, S.1    Greenlees, C.2
  • 14
    • 0028258794 scopus 로고
    • How many people in the world have multiple sclerosis?
    • Dean G. How many people in the world have multiple sclerosis?. Neuroepidemiology 1994, 13:1-7.
    • (1994) Neuroepidemiology , vol.13 , pp. 1-7
    • Dean, G.1
  • 15
    • 0035003031 scopus 로고    scopus 로고
    • Immunomodulatory drugs for multiple sclerosis: a systematic review of clinical and cost effectiveness
    • Clegg A., Bryant J. Immunomodulatory drugs for multiple sclerosis: a systematic review of clinical and cost effectiveness. Expert Opin Pharmacother 2001, 2:623-639.
    • (2001) Expert Opin Pharmacother , vol.2 , pp. 623-639
    • Clegg, A.1    Bryant, J.2
  • 16
  • 18
    • 0035044638 scopus 로고    scopus 로고
    • The neuroimmunology of multiple sclerosis: possible roles of T and B lymphocytes in immunopathogenesis
    • O'Connor K.C., Bar-Or A., Hafler D.A. The neuroimmunology of multiple sclerosis: possible roles of T and B lymphocytes in immunopathogenesis. J Clin Immunol 2001, 21:81-92.
    • (2001) J Clin Immunol , vol.21 , pp. 81-92
    • O'Connor, K.C.1    Bar-Or, A.2    Hafler, D.A.3
  • 20
    • 0033978459 scopus 로고    scopus 로고
    • Animal models for autoimmune demyelinating disorders of the nervous system
    • Gold R., Hartung H.P., Toyka K.V. Animal models for autoimmune demyelinating disorders of the nervous system. Mol Med Today 2000, 6:88-91.
    • (2000) Mol Med Today , vol.6 , pp. 88-91
    • Gold, R.1    Hartung, H.P.2    Toyka, K.V.3
  • 21
    • 0028959239 scopus 로고
    • The immunology of multiple sclerosis and its animal model, experimental allergic encephalomyelitis
    • Owens T., Sriram S. The immunology of multiple sclerosis and its animal model, experimental allergic encephalomyelitis. Neurol Clin 1995, 13:51-73.
    • (1995) Neurol Clin , vol.13 , pp. 51-73
    • Owens, T.1    Sriram, S.2
  • 22
    • 3142724732 scopus 로고    scopus 로고
    • Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis
    • Bettelli E., Sullivan B., Szabo S.J., Sobel R.A., Glimcher L.H., Kuchroo V.K. Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis. J Exp Med 2004, 200:79-87.
    • (2004) J Exp Med , vol.200 , pp. 79-87
    • Bettelli, E.1    Sullivan, B.2    Szabo, S.J.3    Sobel, R.A.4    Glimcher, L.H.5    Kuchroo, V.K.6
  • 23
    • 0345358584 scopus 로고    scopus 로고
    • The IL-12 family of heterodimeric cytokines: new players in the regulation of T cell responses
    • Trinchieri G., Pflanz S., Kastelein R.A. The IL-12 family of heterodimeric cytokines: new players in the regulation of T cell responses. Immunity 2003, 19:641-644.
    • (2003) Immunity , vol.19 , pp. 641-644
    • Trinchieri, G.1    Pflanz, S.2    Kastelein, R.A.3
  • 24
    • 0029093933 scopus 로고
    • The role of IL-12 in the induction of organ-specific autoimmune diseases
    • Trembleau S., Germann T., Gately M.K., Adorini L. The role of IL-12 in the induction of organ-specific autoimmune diseases. Immunol Today 1995, 16:383-386.
    • (1995) Immunol Today , vol.16 , pp. 383-386
    • Trembleau, S.1    Germann, T.2    Gately, M.K.3    Adorini, L.4
  • 26
    • 0034450123 scopus 로고    scopus 로고
    • Molecular mechanisms of NF-kappaB activation induced by bacterial lipopolysaccharide through Toll-like receptors
    • Zhang G., Ghosh S. Molecular mechanisms of NF-kappaB activation induced by bacterial lipopolysaccharide through Toll-like receptors. J Endotoxin Res 2000, 6:453-457.
    • (2000) J Endotoxin Res , vol.6 , pp. 453-457
    • Zhang, G.1    Ghosh, S.2
  • 27
    • 0028234529 scopus 로고
    • Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
    • Darnell J.E., Kerr I.M., Stark G.R. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 1994, 264:1415-1421.
    • (1994) Science , vol.264 , pp. 1415-1421
    • Darnell, J.E.1    Kerr, I.M.2    Stark, G.R.3
  • 28
    • 0032906987 scopus 로고    scopus 로고
    • Differential influence of interleukin-12 in the pathogenesis of autoimmune and virus-induced central nervous system demyelination
    • Bright J.J., Rodriguez M., Sriram S. Differential influence of interleukin-12 in the pathogenesis of autoimmune and virus-induced central nervous system demyelination. J Virol 1999, 73:1637-1639.
    • (1999) J Virol , vol.73 , pp. 1637-1639
    • Bright, J.J.1    Rodriguez, M.2    Sriram, S.3
  • 29
    • 0037434789 scopus 로고    scopus 로고
    • Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain
    • Cua D.J., Sherlock J., Chen Y., Murphy C.A., Joyce B., Seymour B., et al. Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain. Nature 2003, 421:744-748.
    • (2003) Nature , vol.421 , pp. 744-748
    • Cua, D.J.1    Sherlock, J.2    Chen, Y.3    Murphy, C.A.4    Joyce, B.5    Seymour, B.6
  • 30
    • 0345540638 scopus 로고    scopus 로고
    • Oral administration of a turmeric extract inhibits LDL oxidation and has hypocholesterolemic effects in rabbits with experimental atherosclerosis
    • Ramirez-Tortosa M.C., Mesa M.D., Aguilera M.C., Quiles J.L., Baro L., Ramirez-Tortosa C.L., et al. Oral administration of a turmeric extract inhibits LDL oxidation and has hypocholesterolemic effects in rabbits with experimental atherosclerosis. Atherosclerosis 1999, 147:371-378.
    • (1999) Atherosclerosis , vol.147 , pp. 371-378
    • Ramirez-Tortosa, M.C.1    Mesa, M.D.2    Aguilera, M.C.3    Quiles, J.L.4    Baro, L.5    Ramirez-Tortosa, C.L.6
  • 31
    • 0035503597 scopus 로고    scopus 로고
    • The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse
    • Lim G.P., Chu T., Yang F., Beech W., Frautschy S.A., Cole G.M. The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse. J Neurosci 2001, 21:8370-8377.
    • (2001) J Neurosci , vol.21 , pp. 8370-8377
    • Lim, G.P.1    Chu, T.2    Yang, F.3    Beech, W.4    Frautschy, S.A.5    Cole, G.M.6
  • 32
    • 0035957872 scopus 로고    scopus 로고
    • Curcuminoids from Curcuma longa L. (Zingiberaceae) that protect PC12 rat pheochromocytoma and normal human umbilical vein endothelial cells from betaA(1-42) insult
    • Kim D.S., Park S.Y., Kim J.K. Curcuminoids from Curcuma longa L. (Zingiberaceae) that protect PC12 rat pheochromocytoma and normal human umbilical vein endothelial cells from betaA(1-42) insult. Neurosci Lett 2001, 303:57-61.
    • (2001) Neurosci Lett , vol.303 , pp. 57-61
    • Kim, D.S.1    Park, S.Y.2    Kim, J.K.3
  • 33
    • 0031056998 scopus 로고    scopus 로고
    • Presence of an acidic glycoprotein in the serum of arthritic rats: modulation by capsaicin and curcumin
    • Joe B., Rao U.J., Lokesh B.R. Presence of an acidic glycoprotein in the serum of arthritic rats: modulation by capsaicin and curcumin. Mol Cell Biochem 1997, 169:125-134.
    • (1997) Mol Cell Biochem , vol.169 , pp. 125-134
    • Joe, B.1    Rao, U.J.2    Lokesh, B.R.3
  • 34
    • 0018887037 scopus 로고
    • Preliminary study on antirheumatic activity of curcumin (diferuloyl methane)
    • Deodhar S.D., Sethi R., Srimal R.C. Preliminary study on antirheumatic activity of curcumin (diferuloyl methane). Indian J Med Res 1980, 71:632-634.
    • (1980) Indian J Med Res , vol.71 , pp. 632-634
    • Deodhar, S.D.1    Sethi, R.2    Srimal, R.C.3
  • 35
    • 0037097660 scopus 로고    scopus 로고
    • Curcumin inhibits experimental allergic encephalomyelitis by blocking IL-12 signaling through Janus kinase-STAT pathway in T lymphocytes
    • Natarajan C., Bright J.J. Curcumin inhibits experimental allergic encephalomyelitis by blocking IL-12 signaling through Janus kinase-STAT pathway in T lymphocytes. J Immunol 2002, 168:6506-6513.
    • (2002) J Immunol , vol.168 , pp. 6506-6513
    • Natarajan, C.1    Bright, J.J.2
  • 36
    • 63549122337 scopus 로고    scopus 로고
    • Amelioration of experimental autoimmune encephalomyelitis by curcumin treatment through inhibition of IL-17 production
    • Xie L., Li X.K., Funeshima-Fuji N., Kimura H., Matsumoto Y., Isaka Y., et al. Amelioration of experimental autoimmune encephalomyelitis by curcumin treatment through inhibition of IL-17 production. Int Immunopharmacol 2009, 9:575-581.
    • (2009) Int Immunopharmacol , vol.9 , pp. 575-581
    • Xie, L.1    Li, X.K.2    Funeshima-Fuji, N.3    Kimura, H.4    Matsumoto, Y.5    Isaka, Y.6
  • 37
    • 77953536537 scopus 로고    scopus 로고
    • Food preservatives sodium benzoate and propionic acid and colorant curcumin suppress Th1-type immune response in vitro
    • Maier E., Kurz K., Jenny M., Schennach H., Ueberall F., Fuchs D. Food preservatives sodium benzoate and propionic acid and colorant curcumin suppress Th1-type immune response in vitro. Food Chem Toxicol 2010, 48:1950-1956.
    • (2010) Food Chem Toxicol , vol.48 , pp. 1950-1956
    • Maier, E.1    Kurz, K.2    Jenny, M.3    Schennach, H.4    Ueberall, F.5    Fuchs, D.6
  • 38
    • 25844473319 scopus 로고    scopus 로고
    • Protective effects of a peroxisome proliferator-activated receptor-beta/delta agonist in experimental autoimmune encephalomyelitis
    • Polak P.E., Kalinin S., Dello Russo C., Gavrilyuk V., Sharp A., Peters J.M., et al. Protective effects of a peroxisome proliferator-activated receptor-beta/delta agonist in experimental autoimmune encephalomyelitis. J Neuroimmunol 2005, 168:65-75.
    • (2005) J Neuroimmunol , vol.168 , pp. 65-75
    • Polak, P.E.1    Kalinin, S.2    Dello Russo, C.3    Gavrilyuk, V.4    Sharp, A.5    Peters, J.M.6
  • 39
    • 0031769693 scopus 로고    scopus 로고
    • Lack of Th2 cytokine increase during spontaneous remission of experimental allergic encephalomyelitis
    • Di Rosa F., Francesconi A., Di Virgilio A., Finocchi L., Santilio I., Barnaba V. Lack of Th2 cytokine increase during spontaneous remission of experimental allergic encephalomyelitis. Eur J Immunol 1998, 28:3893-3903.
    • (1998) Eur J Immunol , vol.28 , pp. 3893-3903
    • Di Rosa, F.1    Francesconi, A.2    Di Virgilio, A.3    Finocchi, L.4    Santilio, I.5    Barnaba, V.6
  • 40
    • 33746399418 scopus 로고    scopus 로고
    • Curcumin regulated shift from Th1 to Th2 in trinitrobenzene sulphonic acid-induced chronic colitis
    • Zhang M., Deng C.S., Zheng J.J., Xia J. Curcumin regulated shift from Th1 to Th2 in trinitrobenzene sulphonic acid-induced chronic colitis. Acta Pharmacol Sin 2006, 27:1071-1077.
    • (2006) Acta Pharmacol Sin , vol.27 , pp. 1071-1077
    • Zhang, M.1    Deng, C.S.2    Zheng, J.J.3    Xia, J.4
  • 41
    • 70449353464 scopus 로고    scopus 로고
    • Curcumin induces the tolerogenic dendritic cell that promotes differentiation of intestine-protective regulatory T cells
    • Cong Y., Wang L., Konrad A., Schoeb T., Elson C.O. Curcumin induces the tolerogenic dendritic cell that promotes differentiation of intestine-protective regulatory T cells. Eur J Immunol 2009, 39:3134-3146.
    • (2009) Eur J Immunol , vol.39 , pp. 3134-3146
    • Cong, Y.1    Wang, L.2    Konrad, A.3    Schoeb, T.4    Elson, C.O.5
  • 43
    • 51349104881 scopus 로고    scopus 로고
    • 15-deoxy-Delta(12,14)-prostaglandin J(2) and curcumin modulate the expression of toll-like receptors 4 and 9 in autoimmune T lymphocyte
    • Chearwae W., Bright J.J. 15-deoxy-Delta(12,14)-prostaglandin J(2) and curcumin modulate the expression of toll-like receptors 4 and 9 in autoimmune T lymphocyte. J Clin Immunol 2008, 28:558-570.
    • (2008) J Clin Immunol , vol.28 , pp. 558-570
    • Chearwae, W.1    Bright, J.J.2
  • 44
    • 20444402292 scopus 로고    scopus 로고
    • Curcumin inhibits immunostimulatory function of dendritic cells: MAPKs and translocation of NF-kappa B as potential targets
    • Kim G.Y., Kim K.H., Lee S.H., Yoon M.S., Lee H.J., Moon D.O., et al. Curcumin inhibits immunostimulatory function of dendritic cells: MAPKs and translocation of NF-kappa B as potential targets. J Immunol 2005, 174:8116-8124.
    • (2005) J Immunol , vol.174 , pp. 8116-8124
    • Kim, G.Y.1    Kim, K.H.2    Lee, S.H.3    Yoon, M.S.4    Lee, H.J.5    Moon, D.O.6
  • 45
    • 77954545350 scopus 로고    scopus 로고
    • PPARgamma agonist curcumin reduces the amyloid-beta-stimulated inflammatory responses in primary astrocytes
    • Wang H.M., Zhao Y.X., Zhang S., Liu G.D., Kang W.Y., Tang H.D., et al. PPARgamma agonist curcumin reduces the amyloid-beta-stimulated inflammatory responses in primary astrocytes. J Alzheimers Dis 2010, 20:1189-1199.
    • (2010) J Alzheimers Dis , vol.20 , pp. 1189-1199
    • Wang, H.M.1    Zhao, Y.X.2    Zhang, S.3    Liu, G.D.4    Kang, W.Y.5    Tang, H.D.6
  • 46
    • 0036546185 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma agonists inhibit experimental allergic encephalomyelitis by blocking IL-12 production, IL-12 signaling and Th1 differentiation
    • Natarajan C., Bright J.J. Peroxisome proliferator-activated receptor-gamma agonists inhibit experimental allergic encephalomyelitis by blocking IL-12 production, IL-12 signaling and Th1 differentiation. Genes Immun 2002, 3:59-70.
    • (2002) Genes Immun , vol.3 , pp. 59-70
    • Natarajan, C.1    Bright, J.J.2
  • 47
    • 0344153921 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma-deficient heterozygous mice develop an exacerbated neural antigen-induced Th1 response and experimental allergic encephalomyelitis
    • Natarajan C., Muthian G., Barak Y., Evans R.M., Bright J.J. Peroxisome proliferator-activated receptor-gamma-deficient heterozygous mice develop an exacerbated neural antigen-induced Th1 response and experimental allergic encephalomyelitis. J Immunol 2003, 171:5743-5750.
    • (2003) J Immunol , vol.171 , pp. 5743-5750
    • Natarajan, C.1    Muthian, G.2    Barak, Y.3    Evans, R.M.4    Bright, J.J.5
  • 48
    • 35348990389 scopus 로고    scopus 로고
    • Interleukin-10 is upregulated by nanomolar rosiglitazone treatment of mature dendritic cells and human CD4+ T cells
    • Thompson P.W., Bayliffe A.I., Warren A.P., Lamb J.R. Interleukin-10 is upregulated by nanomolar rosiglitazone treatment of mature dendritic cells and human CD4+ T cells. Cytokine 2007, 39:184-191.
    • (2007) Cytokine , vol.39 , pp. 184-191
    • Thompson, P.W.1    Bayliffe, A.I.2    Warren, A.P.3    Lamb, J.R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.