-
1
-
-
48249139449
-
Multiple sclerosis: an immune or neurodegenerative disorder?
-
Trapp BD, Nave KA. Multiple sclerosis: an immune or neurodegenerative disorder? Annu Rev Neurosci 2008; 31: 247-269.
-
(2008)
Annu Rev Neurosci
, vol.31
, pp. 247-269
-
-
Trapp, B.D.1
Nave, K.A.2
-
2
-
-
78751501874
-
Genetically induced adult oligodendrocyte cell death is associated with poor myelin clearance, reduced remyelination, and axonal damage
-
Pohl HB, Porcheri C, Mueggler T, et al. Genetically induced adult oligodendrocyte cell death is associated with poor myelin clearance, reduced remyelination, and axonal damage. J Neurosci 2011; 31: 1069-1080.
-
(2011)
J Neurosci
, vol.31
, pp. 1069-1080
-
-
Pohl, H.B.1
Porcheri, C.2
Mueggler, T.3
-
3
-
-
0032486428
-
Axonal swellings and degeneration in mice lacking the major proteolipid of myelin
-
Griffiths I, Klugmann M, Anderson T, et al. Axonal swellings and degeneration in mice lacking the major proteolipid of myelin. Science 1998; 280: 1610-1613.
-
(1998)
Science
, vol.280
, pp. 1610-1613
-
-
Griffiths, I.1
Klugmann, M.2
Anderson, T.3
-
4
-
-
0030767405
-
Conduction in segmentally demyelinated mammalian central axons
-
Felts PA, Baker TA, Smith KJ. Conduction in segmentally demyelinated mammalian central axons. J Neurosci 1997; 17: 7267-7277.
-
(1997)
J Neurosci
, vol.17
, pp. 7267-7277
-
-
Felts, P.A.1
Baker, T.A.2
Smith, K.J.3
-
5
-
-
0037819578
-
Abnormal sodium channel distribution in optic nerve axons in a model of inflammatory demyelination
-
Craner MJ, Lo AC, Black JA, Waxman SG. Abnormal sodium channel distribution in optic nerve axons in a model of inflammatory demyelination. Brain 2003; 126: 1552-1561.
-
(2003)
Brain
, vol.126
, pp. 1552-1561
-
-
Craner, M.J.1
Lo, A.C.2
Black, J.A.3
Waxman, S.G.4
-
6
-
-
54249124952
-
Remyelination in the CNS: from biology to therapy
-
Franklin RJ, Ffrench-Constant C. Remyelination in the CNS: from biology to therapy. Nat Rev Neurosci 2008; 9: 839-855.
-
(2008)
Nat Rev Neurosci
, vol.9
, pp. 839-855
-
-
Franklin, R.J.1
Ffrench-Constant, C.2
-
7
-
-
0018774226
-
Central remyelination restores secure conduction
-
Smith KJ, Blakemore WF, McDonald WI. Central remyelination restores secure conduction. Nature 1979; 280: 395-396.
-
(1979)
Nature
, vol.280
, pp. 395-396
-
-
Smith, K.J.1
Blakemore, W.F.2
McDonald, W.I.3
-
8
-
-
79959750950
-
Increased mitochondrial content in remyelinated axons: implications for multiple sclerosis
-
Zambonin JL, Zhao C, Ohno N, et al. Increased mitochondrial content in remyelinated axons: implications for multiple sclerosis. Brain 2011; 134: 1901-1913.
-
(2011)
Brain
, vol.134
, pp. 1901-1913
-
-
Zambonin, J.L.1
Zhao, C.2
Ohno, N.3
-
9
-
-
0031050183
-
Locomotor deficits induced by experimental spinal cord demyelination are abolished by spontaneous remyelination
-
Jeffery ND, Blakemore WF. Locomotor deficits induced by experimental spinal cord demyelination are abolished by spontaneous remyelination. Brain 1997; 120 (pt 1): 27-37.
-
(1997)
Brain
, vol.120
, Issue.Pt 1
, pp. 27-37
-
-
Jeffery, N.D.1
Blakemore, W.F.2
-
10
-
-
0033870097
-
Multiple sclerosis and chronic autoimmune encephalomyelitis: a comparative quantitative study of axonal injury in active, inactive, and remyelinated lesions
-
Kornek B, Storch MK, Weissert R, et al. Multiple sclerosis and chronic autoimmune encephalomyelitis: a comparative quantitative study of axonal injury in active, inactive, and remyelinated lesions. Am J Pathol 2000; 157: 267-276.
-
(2000)
Am J Pathol
, vol.157
, pp. 267-276
-
-
Kornek, B.1
Storch, M.K.2
Weissert, R.3
-
11
-
-
44949177395
-
Remyelination protects axons from demyelination-associated axon degeneration
-
Irvine KA, Blakemore WF. Remyelination protects axons from demyelination-associated axon degeneration. Brain 2008; 131: 1464-1477.
-
(2008)
Brain
, vol.131
, pp. 1464-1477
-
-
Irvine, K.A.1
Blakemore, W.F.2
-
12
-
-
84857769209
-
Multiple sclerosis - remyelination failure as a cause of disease progression
-
Hagemeier K, Bruck W, Kuhlmann T. Multiple sclerosis - remyelination failure as a cause of disease progression. Histol Histopathol 2012; 27: 277-287.
-
(2012)
Histol Histopathol
, vol.27
, pp. 277-287
-
-
Hagemeier, K.1
Bruck, W.2
Kuhlmann, T.3
-
13
-
-
84857539822
-
Late motor decline after accomplished remyelination: impact for progressive multiple sclerosis
-
Manrique-Hoyos N, Jurgens T, Gronborg M, et al. Late motor decline after accomplished remyelination: impact for progressive multiple sclerosis. Ann Neurol 2012; 71: 227-244.
-
(2012)
Ann Neurol
, vol.71
, pp. 227-244
-
-
Manrique-Hoyos, N.1
Jurgens, T.2
Gronborg, M.3
-
14
-
-
84862265936
-
Targeted ablation of oligodendrocytes induces axonal pathology independent of overt demyelination
-
Oluich LJ, Stratton JA, Lulu Xing Y, et al. Targeted ablation of oligodendrocytes induces axonal pathology independent of overt demyelination. J Neurosci 2012; 32: 8317-8330.
-
(2012)
J Neurosci
, vol.32
, pp. 8317-8330
-
-
Oluich, L.J.1
Stratton, J.A.2
Lulu Xing, Y.3
-
15
-
-
0016348545
-
Pattern of remyelination in the CNS
-
Blakemore WF. Pattern of remyelination in the CNS. Nature 1974; 249: 577-578.
-
(1974)
Nature
, vol.249
, pp. 577-578
-
-
Blakemore, W.F.1
-
17
-
-
0030785547
-
Identification of post-mitotic oligodendrocytes incapable of remyelination within the demyelinated adult spinal cord
-
Keirstead HS, Blakemore WF. Identification of post-mitotic oligodendrocytes incapable of remyelination within the demyelinated adult spinal cord. J Neuropathol Exp Neurol 1997; 56: 1191-1201.
-
(1997)
J Neuropathol Exp Neurol
, vol.56
, pp. 1191-1201
-
-
Keirstead, H.S.1
Blakemore, W.F.2
-
18
-
-
0030063699
-
Co-localization of NG2 proteoglycan and PDGF alpha-receptor on O2A progenitor cells in the developing rat brain
-
Nishiyama A, Lin XH, Giese N, Heldin CH, Stallcup WB. Co-localization of NG2 proteoglycan and PDGF alpha-receptor on O2A progenitor cells in the developing rat brain. J Neurosci Res 1996; 43: 299-314.
-
(1996)
J Neurosci Res
, vol.43
, pp. 299-314
-
-
Nishiyama, A.1
Lin, X.H.2
Giese, N.3
Heldin, C.H.4
Stallcup, W.B.5
-
19
-
-
0026689059
-
PDGF receptors in the rat CNS: during late neurogenesis, PDGF alpha-receptor expression appears to be restricted to glial cells of the oligodendrocyte lineage
-
Pringle NP, Mudhar HS, Collarini EJ, Richardson WD. PDGF receptors in the rat CNS: during late neurogenesis, PDGF alpha-receptor expression appears to be restricted to glial cells of the oligodendrocyte lineage. Development 1992; 115: 535-551.
-
(1992)
Development
, vol.115
, pp. 535-551
-
-
Pringle, N.P.1
Mudhar, H.S.2
Collarini, E.J.3
Richardson, W.D.4
-
20
-
-
56749156453
-
PDGFRA/NG2 glia generate myelinating oligodendrocytes and piriform projection neurons in adult mice
-
Rivers LE, Young KM, Rizzi M, et al. PDGFRA/NG2 glia generate myelinating oligodendrocytes and piriform projection neurons in adult mice. Nat Neurosci 2008; 11: 1392-1401.
-
(2008)
Nat Neurosci
, vol.11
, pp. 1392-1401
-
-
Rivers, L.E.1
Young, K.M.2
Rizzi, M.3
-
21
-
-
0038077547
-
Efficient central nervous system remyelination requires T cells
-
Bieber AJ, Kerr S, Rodriguez M. Efficient central nervous system remyelination requires T cells. Ann Neurol 2003; 53: 680-684.
-
(2003)
Ann Neurol
, vol.53
, pp. 680-684
-
-
Bieber, A.J.1
Kerr, S.2
Rodriguez, M.3
-
22
-
-
0033082118
-
Demyelination and remyelination of the caudal cerebellar peduncle of adult rats following stereotaxic injections of lysolecithin, ethidium bromide, and complement/anti-galactocerebroside: a comparative study
-
Woodruff RH, Franklin RJ. Demyelination and remyelination of the caudal cerebellar peduncle of adult rats following stereotaxic injections of lysolecithin, ethidium bromide, and complement/anti-galactocerebroside: a comparative study. Glia 1999; 25: 216-228.
-
(1999)
Glia
, vol.25
, pp. 216-228
-
-
Woodruff, R.H.1
Franklin, R.J.2
-
23
-
-
0015303575
-
The effect of injections of lysophosphatidyl choline into white matter of the adult mouse spinal cord
-
Hall SM. The effect of injections of lysophosphatidyl choline into white matter of the adult mouse spinal cord. J Cell Sci 1972; 10: 535-546.
-
(1972)
J Cell Sci
, vol.10
, pp. 535-546
-
-
Hall, S.M.1
-
24
-
-
0020422723
-
Ethidium bromide induced demyelination in the spinal cord of the cat
-
Blakemore WF. Ethidium bromide induced demyelination in the spinal cord of the cat. Neuropathol Appl Neurobiol 1982; 8: 365-375.
-
(1982)
Neuropathol Appl Neurobiol
, vol.8
, pp. 365-375
-
-
Blakemore, W.F.1
-
25
-
-
0018574943
-
Demyelination and remyelination in the rat central nervous system following ethidium bromide injection
-
Yajima K, Suzuki K. Demyelination and remyelination in the rat central nervous system following ethidium bromide injection. Lab Invest 1979; 41: 385-392.
-
(1979)
Lab Invest
, vol.41
, pp. 385-392
-
-
Yajima, K.1
Suzuki, K.2
-
26
-
-
0015842080
-
Demyelination of the superior cerebellar peduncle in the mouse induced by cuprizone
-
Blakemore WF. Demyelination of the superior cerebellar peduncle in the mouse induced by cuprizone. J Neurol Sci 1973; 20: 63-72.
-
(1973)
J Neurol Sci
, vol.20
, pp. 63-72
-
-
Blakemore, W.F.1
-
27
-
-
0018234553
-
Central nervous system demyelination and remyelination in the mouse: an ultrastructural study of cuprizone toxicity
-
Ludwin SK. Central nervous system demyelination and remyelination in the mouse: an ultrastructural study of cuprizone toxicity. Lab Invest 1978; 39: 597-612.
-
(1978)
Lab Invest
, vol.39
, pp. 597-612
-
-
Ludwin, S.K.1
-
28
-
-
0015835355
-
Remyelination of the superior cerebellar peduncle in the mouse following demyelination induced by feeding cuprizone
-
Blakemore WF. Remyelination of the superior cerebellar peduncle in the mouse following demyelination induced by feeding cuprizone. J Neurol Sci 1973; 20: 73-83.
-
(1973)
J Neurol Sci
, vol.20
, pp. 73-83
-
-
Blakemore, W.F.1
-
29
-
-
33646251131
-
Innate immunity triggers oligodendrocyte progenitor reactivity and confines damages to brain injuries
-
Glezer I, Lapointe A, Rivest S. Innate immunity triggers oligodendrocyte progenitor reactivity and confines damages to brain injuries. FASEB J 2006; 20: 750-752.
-
(2006)
FASEB J
, vol.20
, pp. 750-752
-
-
Glezer, I.1
Lapointe, A.2
Rivest, S.3
-
30
-
-
33646348133
-
The injury response of oligodendrocyte precursor cells is induced by platelets, macrophages and inflammation-associated cytokines
-
Rhodes KE, Raivich G, Fawcett JW. The injury response of oligodendrocyte precursor cells is induced by platelets, macrophages and inflammation-associated cytokines. Neuroscience 2006; 140: 87-100.
-
(2006)
Neuroscience
, vol.140
, pp. 87-100
-
-
Rhodes, K.E.1
Raivich, G.2
Fawcett, J.W.3
-
31
-
-
7244226354
-
Increased expression of Nkx2.2 and Olig2 identifies reactive oligodendrocyte progenitor cells responding to demyelination in the adult CNS
-
Fancy SP, Zhao C, Franklin RJ. Increased expression of Nkx2. 2 and Olig2 identifies reactive oligodendrocyte progenitor cells responding to demyelination in the adult CNS. Mol Cell Neurosci 2004; 27: 247-254.
-
(2004)
Mol Cell Neurosci
, vol.27
, pp. 247-254
-
-
Fancy, S.P.1
Zhao, C.2
Franklin, R.J.3
-
32
-
-
79959909381
-
Myelin regeneration: a recapitulation of development?
-
Fancy SP, Chan JR, Baranzini SE, Franklin RJ, Rowitch DH. Myelin regeneration: a recapitulation of development? Annu Rev Neurosci 2011; 34: 21-43.
-
(2011)
Annu Rev Neurosci
, vol.34
, pp. 21-43
-
-
Fancy, S.P.1
Chan, J.R.2
Baranzini, S.E.3
Franklin, R.J.4
Rowitch, D.H.5
-
33
-
-
0033215282
-
Remyelination occurs as extensively but more slowly in old rats compared to young rats following gliotoxin-induced CNS demyelination
-
Shields SA, Gilson JM, Blakemore WF, Franklin RJ. Remyelination occurs as extensively but more slowly in old rats compared to young rats following gliotoxin-induced CNS demyelination. Glia 1999; 28: 77-83.
-
(1999)
Glia
, vol.28
, pp. 77-83
-
-
Shields, S.A.1
Gilson, J.M.2
Blakemore, W.F.3
Franklin, R.J.4
-
34
-
-
0036549138
-
The age-related decrease in CNS remyelination efficiency is attributable to an impairment of both oligodendrocyte progenitor recruitment and differentiation
-
Sim FJ, Zhao C, Penderis J, Franklin RJ. The age-related decrease in CNS remyelination efficiency is attributable to an impairment of both oligodendrocyte progenitor recruitment and differentiation. J Neurosci 2002; 22: 2451-2459.
-
(2002)
J Neurosci
, vol.22
, pp. 2451-2459
-
-
Sim, F.J.1
Zhao, C.2
Penderis, J.3
Franklin, R.J.4
-
35
-
-
0030799817
-
To what extent is oligodendrocyte progenitor migration a limiting factor in the remyelination of multiple sclerosis lesions?
-
Franklin RJ, Blakemore WF. To what extent is oligodendrocyte progenitor migration a limiting factor in the remyelination of multiple sclerosis lesions? Mult Scler 1997; 3: 84-87.
-
(1997)
Mult Scler
, vol.3
, pp. 84-87
-
-
Franklin, R.J.1
Blakemore, W.F.2
-
36
-
-
0030834978
-
Local recruitment of remyelinating cells in the repair of demyelination in the central nervous system
-
Franklin RJ, Gilson JM, Blakemore WF. Local recruitment of remyelinating cells in the repair of demyelination in the central nervous system. J Neurosci Res 1997; 50: 337-344.
-
(1997)
J Neurosci Res
, vol.50
, pp. 337-344
-
-
Franklin, R.J.1
Gilson, J.M.2
Blakemore, W.F.3
-
37
-
-
0038692009
-
Impaired remyelination and depletion of oligodendrocyte progenitors does not occur following repeated episodes of focal demyelination in the rat central nervous system
-
Penderis J, Shields SA, Franklin RJ. Impaired remyelination and depletion of oligodendrocyte progenitors does not occur following repeated episodes of focal demyelination in the rat central nervous system. Brain 2003; 126: 1382-1391.
-
(2003)
Brain
, vol.126
, pp. 1382-1391
-
-
Penderis, J.1
Shields, S.A.2
Franklin, R.J.3
-
38
-
-
77957677989
-
Demyelination versus remyelination in progressive multiple sclerosis
-
Bramow S, Frischer JM, Lassmann H, et al. Demyelination versus remyelination in progressive multiple sclerosis. Brain 2010; 133: 2983-2998.
-
(2010)
Brain
, vol.133
, pp. 2983-2998
-
-
Bramow, S.1
Frischer, J.M.2
Lassmann, H.3
-
39
-
-
0034846364
-
Macrophage depletion impairs oligodendrocyte remyelination following lysolecithin-induced demyelination
-
Kotter MR, Setzu A, Sim FJ, van Rooijen N, Franklin RJ. Macrophage depletion impairs oligodendrocyte remyelination following lysolecithin-induced demyelination. Glia 2001; 35: 204-212.
-
(2001)
Glia
, vol.35
, pp. 204-212
-
-
Kotter, M.R.1
Setzu, A.2
Sim, F.J.3
van Rooijen, N.4
Franklin, R.J.5
-
40
-
-
11844253894
-
Macrophage-depletion induced impairment of experimental cns remyelination is associated with a reduced oligodendrocyte progenitor cell response and altered growth factor expression
-
Kotter MR, Zhao C, van Rooijen N, Franklin RJ. Macrophage-depletion induced impairment of experimental CNS remyelination is associated with a reduced oligodendrocyte progenitor cell response and altered growth factor expression. Neurobiol Dis 2005; 18: 166-175.
-
(2005)
Neurobiol Dis
, vol.18
, pp. 166-175
-
-
Kotter, M.R.1
Zhao, C.2
van Rooijen, N.3
Franklin, R.J.4
-
41
-
-
84862908705
-
Rejuvenation of regeneration in the aging central nervous system
-
Ruckh JM, Zhao JW, Shadrach JL, et al. Rejuvenation of regeneration in the aging central nervous system. Cell Stem Cell 2012; 10: 96-103.
-
(2012)
Cell Stem Cell
, vol.10
, pp. 96-103
-
-
Ruckh, J.M.1
Zhao, J.W.2
Shadrach, J.L.3
-
42
-
-
30644476095
-
Myelin impairs CNS remyelination by inhibiting oligodendrocyte precursor cell differentiation
-
Kotter MR, Li WW, Zhao C, Franklin RJ. Myelin impairs CNS remyelination by inhibiting oligodendrocyte precursor cell differentiation. J Neurosci 2006; 26: 328-332.
-
(2006)
J Neurosci
, vol.26
, pp. 328-332
-
-
Kotter, M.R.1
Li, W.W.2
Zhao, C.3
Franklin, R.J.4
-
43
-
-
0034530520
-
Delayed changes in growth factor gene expression during slow remyelination in the CNS of aged rats
-
Hinks GL, Franklin RJ. Delayed changes in growth factor gene expression during slow remyelination in the CNS of aged rats. Mol Cell Neurosci 2000; 16: 542-556.
-
(2000)
Mol Cell Neurosci
, vol.16
, pp. 542-556
-
-
Hinks, G.L.1
Franklin, R.J.2
-
44
-
-
34247862406
-
Remyelination can be extensive in multiple sclerosis despite a long disease course
-
Patani R, Balaratnam M, Vora A, Reynolds R. Remyelination can be extensive in multiple sclerosis despite a long disease course. Neuropathol Appl Neurobiol 2007; 33: 277-287.
-
(2007)
Neuropathol Appl Neurobiol
, vol.33
, pp. 277-287
-
-
Patani, R.1
Balaratnam, M.2
Vora, A.3
Reynolds, R.4
-
45
-
-
0018410045
-
Remyelination in multiple sclerosis
-
Prineas JW, Connell F. Remyelination in multiple sclerosis. Ann Neurol 1979; 5: 22-31.
-
(1979)
Ann Neurol
, vol.5
, pp. 22-31
-
-
Prineas, J.W.1
Connell, F.2
-
47
-
-
0019860769
-
Multiple sclerosis. Oligodendrocyte survival and proliferation in an active established lesion
-
Raine CS, Scheinberg L, Waltz JM. Multiple sclerosis. Oligodendrocyte survival and proliferation in an active established lesion. Lab Invest 1981; 45: 534-546.
-
(1981)
Lab Invest
, vol.45
, pp. 534-546
-
-
Raine, C.S.1
Scheinberg, L.2
Waltz, J.M.3
-
48
-
-
0021647150
-
Continual breakdown and regeneration of myelin in progressive multiple sclerosis plaques
-
Prineas JW, Kwon EE, Cho ES, Sharer LR. Continual breakdown and regeneration of myelin in progressive multiple sclerosis plaques. Ann N Y Acad Sci 1984; 436: 11-32.
-
(1984)
Ann N Y Acad Sci
, vol.436
, pp. 11-32
-
-
Prineas, J.W.1
Kwon, E.E.2
Cho, E.S.3
Sharer, L.R.4
-
49
-
-
67650079567
-
Remyelination capacity of the MS brain decreases with disease chronicity
-
Goldschmidt T, Antel J, Konig FB, Bruck W, Kuhlmann T. Remyelination capacity of the MS brain decreases with disease chronicity. Neurology 2009; 72: 1914-1921.
-
(2009)
Neurology
, vol.72
, pp. 1914-1921
-
-
Goldschmidt, T.1
Antel, J.2
Konig, F.B.3
Bruck, W.4
Kuhlmann, T.5
-
50
-
-
33845294412
-
Remyelination is extensive in a subset of multiple sclerosis patients
-
Patrikios P, Stadelmann C, Kutzelnigg A, et al. Remyelination is extensive in a subset of multiple sclerosis patients. Brain 2006; 129: 3165-3172.
-
(2006)
Brain
, vol.129
, pp. 3165-3172
-
-
Patrikios, P.1
Stadelmann, C.2
Kutzelnigg, A.3
-
51
-
-
33947547648
-
Extensive cortical remyelination in patients with chronic multiple sclerosis
-
Albert M, Antel J, Bruck W, Stadelmann C. Extensive cortical remyelination in patients with chronic multiple sclerosis. Brain Pathol 2007; 17: 129-138.
-
(2007)
Brain Pathol
, vol.17
, pp. 129-138
-
-
Albert, M.1
Antel, J.2
Bruck, W.3
Stadelmann, C.4
-
52
-
-
46849098585
-
Differentiation block of oligodendroglial progenitor cells as a cause for remyelination failure in chronic multiple sclerosis
-
Kuhlmann T, Miron V, Cui Q, et al. Differentiation block of oligodendroglial progenitor cells as a cause for remyelination failure in chronic multiple sclerosis. Brain 2008; 131: 1749-1758.
-
(2008)
Brain
, vol.131
, pp. 1749-1758
-
-
Kuhlmann, T.1
Miron, V.2
Cui, Q.3
-
53
-
-
0031962240
-
Chronic stage multiple sclerosis lesions contain a relatively quiescent population of oligodendrocyte precursor cells
-
Wolswijk G. Chronic stage multiple sclerosis lesions contain a relatively quiescent population of oligodendrocyte precursor cells. J Neurosci 1998; 18: 601-609.
-
(1998)
J Neurosci
, vol.18
, pp. 601-609
-
-
Wolswijk, G.1
-
54
-
-
0037122960
-
Premyelinating oligodendrocytes in chronic lesions of multiple sclerosis
-
Chang A, Tourtellotte WW, Rudick R, Trapp BD. Premyelinating oligodendrocytes in chronic lesions of multiple sclerosis. N Engl J Med 2002; 346: 165-173.
-
(2002)
N Engl J Med
, vol.346
, pp. 165-173
-
-
Chang, A.1
Tourtellotte, W.W.2
Rudick, R.3
Trapp, B.D.4
-
55
-
-
79953890862
-
Glatiramer acetate in the treatment of multiple sclerosis: emerging concepts regarding its mechanism of action
-
Lalive PH, Neuhaus O, Benkhoucha M, et al. Glatiramer acetate in the treatment of multiple sclerosis: emerging concepts regarding its mechanism of action. CNS Drugs 2011; 25: 401-414.
-
(2011)
CNS Drugs
, vol.25
, pp. 401-414
-
-
Lalive, P.H.1
Neuhaus, O.2
Benkhoucha, M.3
-
56
-
-
0034882744
-
Glatiramer acetate induces a Th2-biased response and crossreactivity with myelin basic protein in patients with MS
-
Chen M, Gran B, Costello K, et al. Glatiramer acetate induces a Th2-biased response and crossreactivity with myelin basic protein in patients with MS. Mult Scler 2001; 7: 209-219.
-
(2001)
Mult Scler
, vol.7
, pp. 209-219
-
-
Chen, M.1
Gran, B.2
Costello, K.3
-
57
-
-
0037406714
-
Glatiramer acetate (copolymer-1, copaxone) promotes Th2 cell development and increased IL-10 production through modulation of dendritic cells
-
Vieira PL, Heystek HC, Wormmeester J, Wierenga EA, Kapsenberg ML. Glatiramer acetate (copolymer-1, copaxone) promotes Th2 cell development and increased IL-10 production through modulation of dendritic cells. J Immunol 2003; 170: 4483-4488.
-
(2003)
J Immunol
, vol.170
, pp. 4483-4488
-
-
Vieira, P.L.1
Heystek, H.C.2
Wormmeester, J.3
Wierenga, E.A.4
Kapsenberg, M.L.5
-
58
-
-
34547699396
-
Type II monocytes modulate T cell-mediated central nervous system autoimmune disease
-
Weber MS, Prod'homme T, Youssef S, et al. Type II monocytes modulate T cell-mediated central nervous system autoimmune disease. Nat Med 2007; 13: 935-943.
-
(2007)
Nat Med
, vol.13
, pp. 935-943
-
-
Weber, M.S.1
Prod'homme, T.2
Youssef, S.3
-
59
-
-
18144387626
-
Induction of CD4+CD25+ regulatory T cells by copolymer-I through activation of transcription factor Foxp3
-
Hong J, Li N, Zhang X, Zheng B, Zhang JZ. Induction of CD4+CD25+ regulatory T cells by copolymer-I through activation of transcription factor Foxp3. Proc Natl Acad Sci U S A 2005; 102: 6449-6454.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 6449-6454
-
-
Hong, J.1
Li, N.2
Zhang, X.3
Zheng, B.4
Zhang, J.Z.5
-
60
-
-
49649090657
-
Demyelination arrest and remyelination induced by glatiramer acetate treatment of experimental autoimmune encephalomyelitis
-
Aharoni R, Herschkovitz A, Eilam R, et al. Demyelination arrest and remyelination induced by glatiramer acetate treatment of experimental autoimmune encephalomyelitis. Proc Natl Acad Sci U S A 2008; 105: 11358-11363.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 11358-11363
-
-
Aharoni, R.1
Herschkovitz, A.2
Eilam, R.3
-
61
-
-
70349815768
-
Promoting oligodendrogenesis and myelin repair using the multiple sclerosis medication glatiramer acetate
-
Skihar V, Silva C, Chojnacki A, et al. Promoting oligodendrogenesis and myelin repair using the multiple sclerosis medication glatiramer acetate. Proc Natl Acad Sci U S A 2009; 106: 17992-17997.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 17992-17997
-
-
Skihar, V.1
Silva, C.2
Chojnacki, A.3
-
62
-
-
80755139618
-
Distinct pathological patterns in relapsing-remitting and chronic models of experimental autoimmune enchephalomyelitis and the neuroprotective effect of glatiramer acetate
-
Aharoni R, Vainshtein A, Stock A, et al. Distinct pathological patterns in relapsing-remitting and chronic models of experimental autoimmune enchephalomyelitis and the neuroprotective effect of glatiramer acetate. J Autoimmun 2011; 37: 228-241.
-
(2011)
J Autoimmun
, vol.37
, pp. 228-241
-
-
Aharoni, R.1
Vainshtein, A.2
Stock, A.3
-
63
-
-
77956649226
-
Glatiramer acetate-reactive T lymphocytes regulate oligodendrocyte progenitor cell number in vitro: role of IGF-2
-
Zhang Y, Jalili F, Ouamara N, et al. Glatiramer acetate-reactive T lymphocytes regulate oligodendrocyte progenitor cell number in vitro: role of IGF-2. J Neuroimmunol 2010; 227: 71-79.
-
(2010)
J Neuroimmunol
, vol.227
, pp. 71-79
-
-
Zhang, Y.1
Jalili, F.2
Ouamara, N.3
-
64
-
-
30044451754
-
The immunomodulator glatiramer acetate augments the expression of neurotrophic factors in brains of experimental autoimmune encephalomyelitis mice
-
Aharoni R, Eilam R, Domev H, et al. The immunomodulator glatiramer acetate augments the expression of neurotrophic factors in brains of experimental autoimmune encephalomyelitis mice. Proc Natl Acad Sci U S A 2005; 102: 19045-19050.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 19045-19050
-
-
Aharoni, R.1
Eilam, R.2
Domev, H.3
-
65
-
-
0035795018
-
Humoral and cellular immune responses to copolymer 1 in multiple sclerosis patients treated with copaxone
-
Brenner T, Arnon R, Sela M, et al. Humoral and cellular immune responses to copolymer 1 in multiple sclerosis patients treated with copaxone. J Neuroimmunol 2001; 115: 152-160.
-
(2001)
J Neuroimmunol
, vol.115
, pp. 152-160
-
-
Brenner, T.1
Arnon, R.2
Sela, M.3
-
66
-
-
0036675279
-
Polyreactive antibodies to glatiramer acetate promote myelin repair in murine model of demyelinating disease
-
Ure DR, Rodriguez M. Polyreactive antibodies to glatiramer acetate promote myelin repair in murine model of demyelinating disease. FASEB J 2002; 16: 1260-1262.
-
(2002)
FASEB J
, vol.16
, pp. 1260-1262
-
-
Ure, D.R.1
Rodriguez, M.2
-
67
-
-
79955455801
-
Mechanisms of fingolimod's efficacy and adverse effects in multiple sclerosis
-
Cohen JA, Chun J. Mechanisms of fingolimod's efficacy and adverse effects in multiple sclerosis. Ann Neurol 2011; 69: 759-777.
-
(2011)
Ann Neurol
, vol.69
, pp. 759-777
-
-
Cohen, J.A.1
Chun, J.2
-
68
-
-
35348940243
-
Functional consequences of S1P receptor modulation in rat oligodendroglial lineage cells
-
Jung CG, Kim HJ, Miron VE, et al. Functional consequences of S1P receptor modulation in rat oligodendroglial lineage cells. Glia 2007; 55: 1656-1667.
-
(2007)
Glia
, vol.55
, pp. 1656-1667
-
-
Jung, C.G.1
Kim, H.J.2
Miron, V.E.3
-
69
-
-
35548984947
-
The immunomodulator FTY720 has a direct cytoprotective effect in oligodendrocyte progenitors
-
Coelho RP, Payne SG, Bittman R, Spiegel S, Sato-Bigbee C. The immunomodulator FTY720 has a direct cytoprotective effect in oligodendrocyte progenitors. J Pharmacol Exp Ther 2007; 323: 626-635.
-
(2007)
J Pharmacol Exp Ther
, vol.323
, pp. 626-635
-
-
Coelho, R.P.1
Payne, S.G.2
Bittman, R.3
Spiegel, S.4
Sato-Bigbee, C.5
-
70
-
-
39049125218
-
FTY720 modulates human oligodendrocyte progenitor process extension and survival
-
Miron VE, Jung CG, Kim HJ, et al. FTY720 modulates human oligodendrocyte progenitor process extension and survival. Ann Neurol 2008; 63: 61-71.
-
(2008)
Ann Neurol
, vol.63
, pp. 61-71
-
-
Miron, V.E.1
Jung, C.G.2
Kim, H.J.3
-
71
-
-
53149089045
-
Cyclical and dose-dependent responses of adult human mature oligodendrocytes to fingolimod
-
Miron VE, Hall JA, Kennedy TE, Soliven B, Antel JP. Cyclical and dose-dependent responses of adult human mature oligodendrocytes to fingolimod. Am J Pathol 2008; 173: 1143-1152.
-
(2008)
Am J Pathol
, vol.173
, pp. 1143-1152
-
-
Miron, V.E.1
Hall, J.A.2
Kennedy, T.E.3
Soliven, B.4
Antel, J.P.5
-
72
-
-
79959846854
-
Fingolimod modulates microglial activation to augment markers of remyelination
-
Jackson SJ, Giovannoni G, Baker D. Fingolimod modulates microglial activation to augment markers of remyelination. J Neuroinflammation 2011; 8: 76.
-
(2011)
J Neuroinflammation
, vol.8
, pp. 76
-
-
Jackson, S.J.1
Giovannoni, G.2
Baker, D.3
-
73
-
-
77953225859
-
Fingolimod (FTY720) enhances remyelination following demyelination of organotypic cerebellar slices
-
Miron VE, Ludwin SK, Darlington PJ, et al. Fingolimod (FTY720) enhances remyelination following demyelination of organotypic cerebellar slices. Am J Pathol 2010; 176: 2682-2694.
-
(2010)
Am J Pathol
, vol.176
, pp. 2682-2694
-
-
Miron, V.E.1
Ludwin, S.K.2
Darlington, P.J.3
-
74
-
-
79955645727
-
Neurobiological effects of sphingosine 1-phosphate receptor modulation in the cuprizone model
-
Kim HJ, Miron VE, Dukala D, et al. Neurobiological effects of sphingosine 1-phosphate receptor modulation in the cuprizone model. FASEB J 2011; 25: 1509-1518.
-
(2011)
FASEB J
, vol.25
, pp. 1509-1518
-
-
Kim, H.J.1
Miron, V.E.2
Dukala, D.3
-
75
-
-
79960895505
-
Sphingosine 1-phosphate receptor modulator fingolimod (FTY720) does not promote remyelination in vivo
-
Hu Y, Lee X, Ji B, et al. Sphingosine 1-phosphate receptor modulator fingolimod (FTY720) does not promote remyelination in vivo. Mol Cell Neurosci 2011; 48: 72-81.
-
(2011)
Mol Cell Neurosci
, vol.48
, pp. 72-81
-
-
Hu, Y.1
Lee, X.2
Ji, B.3
-
76
-
-
79960258821
-
Immunosuppression with FTY720 is insufficient to prevent secondary progressive neurodegeneration in experimental autoimmune encephalomyelitis
-
Al-Izki S, Pryce G, Jackson SJ, Giovannoni G, Baker D. Immunosuppression with FTY720 is insufficient to prevent secondary progressive neurodegeneration in experimental autoimmune encephalomyelitis. Mult Scler 2011; 17: 939-948.
-
(2011)
Mult Scler
, vol.17
, pp. 939-948
-
-
Al-Izki, S.1
Pryce, G.2
Jackson, S.J.3
Giovannoni, G.4
Baker, D.5
-
77
-
-
84866355653
-
Placebo-controlled phase 3 study of oral BG-12 or glatiramer in multiple sclerosis
-
Fox RJ, Miller DH, Phillips, JT, et al. Placebo-controlled phase 3 study of oral BG-12 or glatiramer in multiple sclerosis. N Engl J Med 2012; 367: 1087-1097.
-
(2012)
N Engl J Med
, vol.367
, pp. 1087-1097
-
-
Fox, R.J.1
Miller, D.H.2
Phillips, J.T.3
-
78
-
-
84866423965
-
Placebo-controlled phase 3 study of oral BG-12 for relapsing multiple sclerosis
-
Gold R, Kappos L, Arnold DL, et al. Placebo-controlled phase 3 study of oral BG-12 for relapsing multiple sclerosis. N Engl J Med 2012; 367: 1098-1107.
-
(2012)
N Engl J Med
, vol.367
, pp. 1098-1107
-
-
Gold, R.1
Kappos, L.2
Arnold, D.L.3
-
79
-
-
79952136166
-
Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway
-
Linker RA, Lee DH, Ryan S, et al. Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway. Brain 2011; 134: 678-692.
-
(2011)
Brain
, vol.134
, pp. 678-692
-
-
Linker, R.A.1
Lee, D.H.2
Ryan, S.3
-
80
-
-
77955478688
-
Effects of fumaric acids on cuprizone induced central nervous system de- and remyelination in the mouse
-
Moharregh-Khiabani D, Blank A, Skripuletz T, et al. Effects of fumaric acids on cuprizone induced central nervous system de- and remyelination in the mouse. PLoS One 2010; 5: e11769.
-
(2010)
PLoS One
, vol.5
-
-
Moharregh-Khiabani, D.1
Blank, A.2
Skripuletz, T.3
-
81
-
-
84858217865
-
Placebo-controlled trial of oral laquinimod for multiple sclerosis
-
Comi G, Jeffery D, Kappos L, et al. Placebo-controlled trial of oral laquinimod for multiple sclerosis. N Engl J Med 2012; 366: 1000-1009.
-
(2012)
N Engl J Med
, vol.366
, pp. 1000-1009
-
-
Comi, G.1
Jeffery, D.2
Kappos, L.3
-
82
-
-
84865863065
-
Reduced astrocytic NF-kappaB activation by laquinimod protects from cuprizone-induced demyelination
-
Bruck W, Pfortner R, Pham T, et al. Reduced astrocytic NF-kappaB activation by laquinimod protects from cuprizone-induced demyelination. Acta Neuropathol 2012; 124: 411-424.
-
(2012)
Acta Neuropathol
, vol.124
, pp. 411-424
-
-
Bruck, W.1
Pfortner, R.2
Pham, T.3
-
83
-
-
84864121213
-
Voxel-wise magnetization transfer imaging study of effects of natalizumab and IFNbeta-1a in multiple sclerosis
-
Zivadinov R, Dwyer M, Hussein S, et al. Voxel-wise magnetization transfer imaging study of effects of natalizumab and IFNbeta-1a in multiple sclerosis. Mult Scler 2012; 18: 1125-1134.
-
(2012)
Mult Scler
, vol.18
, pp. 1125-1134
-
-
Zivadinov, R.1
Dwyer, M.2
Hussein, S.3
-
84
-
-
0037135989
-
Notch1 control of oligodendrocyte differentiation in the spinal cord
-
Genoud S, Lappe-Siefke C, Goebbels S, et al. Notch1 control of oligodendrocyte differentiation in the spinal cord. J Cell Biol 2002; 158: 709-718.
-
(2002)
J Cell Biol
, vol.158
, pp. 709-718
-
-
Genoud, S.1
Lappe-Siefke, C.2
Goebbels, S.3
-
85
-
-
0032126751
-
Notch receptor activation inhibits oligodendrocyte differentiation
-
Wang S, Sdrulla AD, diSibio G, et al. Notch receptor activation inhibits oligodendrocyte differentiation. Neuron 1998; 21: 63-75.
-
(1998)
Neuron
, vol.21
, pp. 63-75
-
-
Wang, S.1
Sdrulla, A.D.2
diSibio, G.3
-
86
-
-
0033854551
-
Basic helix-loop-helix proteins and the timing of oligodendrocyte differentiation
-
Kondo T, Raff M. Basic helix-loop-helix proteins and the timing of oligodendrocyte differentiation. Development 2000; 127: 2989-2998.
-
(2000)
Development
, vol.127
, pp. 2989-2998
-
-
Kondo, T.1
Raff, M.2
-
87
-
-
0036799650
-
Multiple sclerosis: re-expression of a developmental pathway that restricts oligodendrocyte maturation
-
John GR, Shankar SL, Shafit-Zagardo B, et al. Multiple sclerosis: re-expression of a developmental pathway that restricts oligodendrocyte maturation. Nat Med 2002; 8: 1115-1121.
-
(2002)
Nat Med
, vol.8
, pp. 1115-1121
-
-
John, G.R.1
Shankar, S.L.2
Shafit-Zagardo, B.3
-
88
-
-
4344625746
-
Notch1 and Jagged1 are expressed after CNS demyelination, but are not a major rate-determining factor during remyelination
-
Stidworthy MF, Genoud S, Li WW, et al. Notch1 and Jagged1 are expressed after CNS demyelination, but are not a major rate-determining factor during remyelination. Brain 2004; 127: 1928-1941.
-
(2004)
Brain
, vol.127
, pp. 1928-1941
-
-
Stidworthy, M.F.1
Genoud, S.2
Li, W.W.3
-
89
-
-
28444492982
-
Inhibition of Notch signaling enhances tissue repair in an animal model of multiple sclerosis
-
Jurynczyk M, Jurewicz A, Bielecki B, Raine CS, Selmaj K. Inhibition of Notch signaling enhances tissue repair in an animal model of multiple sclerosis. J Neuroimmunol 2005; 170: 3-10.
-
(2005)
J Neuroimmunol
, vol.170
, pp. 3-10
-
-
Jurynczyk, M.1
Jurewicz, A.2
Bielecki, B.3
Raine, C.S.4
Selmaj, K.5
-
90
-
-
33846510430
-
Notch1 and its ligand Jagged1 are present in remyelination in a T-cell- and antibody-mediated model of inflammatory demyelination
-
Seifert T, Bauer J, Weissert R, Fazekas F, Storch MK. Notch1 and its ligand Jagged1 are present in remyelination in a T-cell- and antibody-mediated model of inflammatory demyelination. Acta Neuropathol 2007; 113: 195-203.
-
(2007)
Acta Neuropathol
, vol.113
, pp. 195-203
-
-
Seifert, T.1
Bauer, J.2
Weissert, R.3
Fazekas, F.4
Storch, M.K.5
-
91
-
-
73149124029
-
Notch1 signaling plays a role in regulating precursor differentiation during CNS remyelination
-
Zhang Y, Argaw AT, Gurfein BT, et al. Notch1 signaling plays a role in regulating precursor differentiation during CNS remyelination. Proc Natl Acad Sci U S A 2009; 106: 19162-19167.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 19162-19167
-
-
Zhang, Y.1
Argaw, A.T.2
Gurfein, B.T.3
-
92
-
-
10744233414
-
F3/contactin acts as a functional ligand for Notch during oligodendrocyte maturation
-
Hu QD, Ang BT, Karsak M, et al. F3/contactin acts as a functional ligand for Notch during oligodendrocyte maturation. Cell 2003; 115: 163-175.
-
(2003)
Cell
, vol.115
, pp. 163-175
-
-
Hu, Q.D.1
Ang, B.T.2
Karsak, M.3
-
93
-
-
61749099508
-
Abnormal expression of TIP30 and arrested nucleocytoplasmic transport within oligodendrocyte precursor cells in multiple sclerosis
-
Nakahara J, Kanekura K, Nawa M, Aiso S, Suzuki N. Abnormal expression of TIP30 and arrested nucleocytoplasmic transport within oligodendrocyte precursor cells in multiple sclerosis. J Clin Invest 2009; 119: 169-181.
-
(2009)
J Clin Invest
, vol.119
, pp. 169-181
-
-
Nakahara, J.1
Kanekura, K.2
Nawa, M.3
Aiso, S.4
Suzuki, N.5
-
94
-
-
61749083654
-
Revisiting notch in remyelination of multiple sclerosis lesions
-
Brosnan CF, John GR. Revisiting Notch in remyelination of multiple sclerosis lesions. J Clin Invest 2009; 119: 10-13.
-
(2009)
J Clin Invest
, vol.119
, pp. 10-13
-
-
Brosnan, C.F.1
John, G.R.2
-
95
-
-
20444363086
-
Wnt signaling controls the timing of oligodendrocyte development in the spinal cord
-
Shimizu T, Kagawa T, Wada T, et al. Wnt signaling controls the timing of oligodendrocyte development in the spinal cord. Dev Biol 2005; 282: 397-410.
-
(2005)
Dev Biol
, vol.282
, pp. 397-410
-
-
Shimizu, T.1
Kagawa, T.2
Wada, T.3
-
96
-
-
69249203776
-
Wnt signaling is sufficient to perturb oligodendrocyte maturation
-
Feigenson K, Reid M, See J, Crenshaw EB, 3rd, Grinspan JB. Wnt signaling is sufficient to perturb oligodendrocyte maturation. Mol Cell Neurosci 2009; 42: 255-265.
-
(2009)
Mol Cell Neurosci
, vol.42
, pp. 255-265
-
-
Feigenson, K.1
Reid, M.2
See, J.3
Crenshaw 3rd, E.B.4
Grinspan, J.B.5
-
97
-
-
77957736585
-
Wnts influence the timing and efficiency of oligodendrocyte precursor cell generation in the telencephalon
-
Langseth AJ, Munji RN, Choe Y, et al. Wnts influence the timing and efficiency of oligodendrocyte precursor cell generation in the telencephalon. J Neurosci 2010; 30: 13367-13372.
-
(2010)
J Neurosci
, vol.30
, pp. 13367-13372
-
-
Langseth, A.J.1
Munji, R.N.2
Choe, Y.3
-
98
-
-
23844520707
-
Wnt signaling regulates the sequential onset of neurogenesis and gliogenesis via induction of BMPs
-
Kasai M, Satoh K, Akiyama T. Wnt signaling regulates the sequential onset of neurogenesis and gliogenesis via induction of BMPs. Genes Cells 2005; 10: 777-783.
-
(2005)
Genes Cells
, vol.10
, pp. 777-783
-
-
Kasai, M.1
Satoh, K.2
Akiyama, T.3
-
99
-
-
80053224227
-
SRY-box containing gene 17 regulates the Wnt/beta-catenin signaling pathway in oligodendrocyte progenitor cells
-
Chew LJ, Shen W, Ming X, et al. SRY-box containing gene 17 regulates the Wnt/beta-catenin signaling pathway in oligodendrocyte progenitor cells. J Neurosci 2011; 31: 13921-13935.
-
(2011)
J Neurosci
, vol.31
, pp. 13921-13935
-
-
Chew, L.J.1
Shen, W.2
Ming, X.3
-
100
-
-
67649797866
-
HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction
-
Ye F, Chen Y, Hoang T, et al. HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction. Nat Neurosci 2009; 12: 829-838.
-
(2009)
Nat Neurosci
, vol.12
, pp. 829-838
-
-
Ye, F.1
Chen, Y.2
Hoang, T.3
-
101
-
-
67649655942
-
Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS
-
Fancy SP, Baranzini SE, Zhao C, et al. Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS. Genes Dev 2009; 23: 1571-1585.
-
(2009)
Genes Dev
, vol.23
, pp. 1571-1585
-
-
Fancy, S.P.1
Baranzini, S.E.2
Zhao, C.3
-
102
-
-
80052972299
-
Canonical Wnt signalling requires the BMP pathway to inhibit oligodendrocyte maturation
-
Feigenson K, Reid M, See J, Crenshaw IE, Grinspan JB. Canonical Wnt signalling requires the BMP pathway to inhibit oligodendrocyte maturation. ASN Neuro 2011; 3: e00061.
-
(2011)
ASN Neuro
, vol.3
-
-
Feigenson, K.1
Reid, M.2
See, J.3
Crenshaw, I.E.4
Grinspan, J.B.5
-
103
-
-
84860669184
-
Differential modulation of the oligodendrocyte transcriptome by sonic hedgehog and bone morphogenetic protein 4 via opposing effects on histone acetylation
-
Wu M, Hernandez M, Shen S, et al. Differential modulation of the oligodendrocyte transcriptome by sonic hedgehog and bone morphogenetic protein 4 via opposing effects on histone acetylation. J Neurosci 2012; 32: 6651-6664.
-
(2012)
J Neurosci
, vol.32
, pp. 6651-6664
-
-
Wu, M.1
Hernandez, M.2
Shen, S.3
-
104
-
-
79952406070
-
Wnt/beta-catenin signaling is an essential and direct driver of myelin gene expression and myelinogenesis
-
Tawk M, Makoukji J, Belle M, et al. Wnt/beta-catenin signaling is an essential and direct driver of myelin gene expression and myelinogenesis. J Neurosci 2011; 31: 3729-3742.
-
(2011)
J Neurosci
, vol.31
, pp. 3729-3742
-
-
Tawk, M.1
Makoukji, J.2
Belle, M.3
-
105
-
-
78650632445
-
Retinoid X receptor gamma signaling accelerates cns remyelination
-
Huang JK, Jarjour AA, Nait Oumesmar B, et al. Retinoid X receptor gamma signaling accelerates CNS remyelination. Nat Neurosci 2011; 14: 45-53.
-
(2011)
Nat Neurosci
, vol.14
, pp. 45-53
-
-
Huang, J.K.1
Jarjour, A.A.2
Nait Oumesmar, B.3
-
106
-
-
33751533155
-
International Union of Pharmacology. LXIII. Retinoid X receptors
-
Germain P, Chambon P, Eichele G, et al. International Union of Pharmacology. LXIII. Retinoid X receptors. Pharmacol Rev 2006; 58: 760-772.
-
(2006)
Pharmacol Rev
, vol.58
, pp. 760-772
-
-
Germain, P.1
Chambon, P.2
Eichele, G.3
-
107
-
-
84860358520
-
Expression of retinoid X receptor beta is induced in astrocytes during corpus callosum demyelination
-
Konig R, Stillfried M, Aperdannier P, et al. Expression of retinoid X receptor beta is induced in astrocytes during corpus callosum demyelination. J Chem Neuroanat 2012; 43: 120-132.
-
(2012)
J Chem Neuroanat
, vol.43
, pp. 120-132
-
-
Konig, R.1
Stillfried, M.2
Aperdannier, P.3
-
108
-
-
77952096362
-
Vitamins E and D3 attenuate demyelination and potentiate remyelination processes of hippocampal formation of rats following local injection of ethidium bromide
-
Goudarzvand M, Javan M, Mirnajafi-Zadeh J, Mozafari S, Tiraihi T. Vitamins E and D3 attenuate demyelination and potentiate remyelination processes of hippocampal formation of rats following local injection of ethidium bromide. Cell Mol Neurobiol 2010; 30: 289-299.
-
(2010)
Cell Mol Neurobiol
, vol.30
, pp. 289-299
-
-
Goudarzvand, M.1
Javan, M.2
Mirnajafi-Zadeh, J.3
Mozafari, S.4
Tiraihi, T.5
-
109
-
-
50249179101
-
Vitamin effects on the immune system: vitamins A and D take centre stage
-
Mora JR, Iwata M, von Andrian UH. Vitamin effects on the immune system: vitamins A and D take centre stage. Nat Rev Immunol 2008; 8: 685-698.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 685-698
-
-
Mora, J.R.1
Iwata, M.2
von Andrian, U.H.3
-
110
-
-
0037101608
-
Directional guidance of oligodendroglial migration by class 3 semaphorins and netrin-1
-
Spassky N, de Castro F, Le Bras B, et al. Directional guidance of oligodendroglial migration by class 3 semaphorins and netrin-1. J Neurosci 2002; 22: 5992-6004.
-
(2002)
J Neurosci
, vol.22
, pp. 5992-6004
-
-
Spassky, N.1
de Castro, F.2
Le Bras, B.3
-
111
-
-
79953653879
-
Class 3 semaphorins influence oligodendrocyte precursor recruitment and remyelination in adult central nervous system
-
Piaton G, Aigrot MS, Williams A, et al. Class 3 semaphorins influence oligodendrocyte precursor recruitment and remyelination in adult central nervous system. Brain 2011; 134: 1156-1167.
-
(2011)
Brain
, vol.134
, pp. 1156-1167
-
-
Piaton, G.1
Aigrot, M.S.2
Williams, A.3
-
112
-
-
79952385046
-
Inhibition of CNS remyelination by the presence of semaphorin 3A
-
Syed YA, Hand E, Mobius W, et al. Inhibition of CNS remyelination by the presence of semaphorin 3A. J Neurosci 2011; 31: 3719-3728.
-
(2011)
J Neurosci
, vol.31
, pp. 3719-3728
-
-
Syed, Y.A.1
Hand, E.2
Mobius, W.3
-
113
-
-
34848854529
-
Semaphorin 3A and 3F: key players in myelin repair in multiple sclerosis?
-
Williams A, Piaton G, Aigrot MS, et al. Semaphorin 3A and 3F: key players in myelin repair in multiple sclerosis? Brain 2007; 130: 2554-2565.
-
(2007)
Brain
, vol.130
, pp. 2554-2565
-
-
Williams, A.1
Piaton, G.2
Aigrot, M.S.3
-
114
-
-
10744222190
-
LINGO-1 is a component of the Nogo-66 receptor/p75 signaling complex
-
Mi S, Lee X, Shao Z, et al. LINGO-1 is a component of the Nogo-66 receptor/p75 signaling complex. Nat Neurosci 2004; 7: 221-228.
-
(2004)
Nat Neurosci
, vol.7
, pp. 221-228
-
-
Mi, S.1
Lee, X.2
Shao, Z.3
-
115
-
-
22844453047
-
LINGO-1 negatively regulates myelination by oligodendrocytes
-
Mi S, Miller RH, Lee X, et al. LINGO-1 negatively regulates myelination by oligodendrocytes. Nat Neurosci 2005; 8: 745-751.
-
(2005)
Nat Neurosci
, vol.8
, pp. 745-751
-
-
Mi, S.1
Miller, R.H.2
Lee, X.3
-
116
-
-
84862667140
-
LINGO-1, a transmembrane signaling protein, inhibits oligodendrocyte differentiation and myelination through intercellular self-interactions
-
Jepson S, Vought B, Gross CH, et al. LINGO-1, a transmembrane signaling protein, inhibits oligodendrocyte differentiation and myelination through intercellular self-interactions. J Biol Chem 2012; 287: 22184-22195.
-
(2012)
J Biol Chem
, vol.287
, pp. 22184-22195
-
-
Jepson, S.1
Vought, B.2
Gross, C.H.3
-
117
-
-
33846128124
-
NGF regulates the expression of axonal LINGO-1 to inhibit oligodendrocyte differentiation and myelination
-
Lee X, Yang Z, Shao Z, et al. NGF regulates the expression of axonal LINGO-1 to inhibit oligodendrocyte differentiation and myelination. J Neurosci 2007; 27: 220-225.
-
(2007)
J Neurosci
, vol.27
, pp. 220-225
-
-
Lee, X.1
Yang, Z.2
Shao, Z.3
-
118
-
-
65249142739
-
Promotion of central nervous system remyelination by induced differentiation of oligodendrocyte precursor cells
-
Mi S, Miller RH, Tang W, et al. Promotion of central nervous system remyelination by induced differentiation of oligodendrocyte precursor cells. Ann Neurol 2009; 65: 304-315.
-
(2009)
Ann Neurol
, vol.65
, pp. 304-315
-
-
Mi, S.1
Miller, R.H.2
Tang, W.3
-
119
-
-
34948888764
-
LINGO-1 antagonist promotes spinal cord remyelination and axonal integrity in mog-induced experimental autoimmune encephalomyelitis
-
Mi S, Hu B, Hahm K, et al. LINGO-1 antagonist promotes spinal cord remyelination and axonal integrity in mog-induced experimental autoimmune encephalomyelitis. Nat Med 2007; 13: 1228-1233.
-
(2007)
Nat Med
, vol.13
, pp. 1228-1233
-
-
Mi, S.1
Hu, B.2
Hahm, K.3
-
120
-
-
80054787044
-
Exposure levels of anti-LINGO-1 Li81 antibody in the central nervous system and dose-efficacy relationships in rat spinal cord remyelination models after systemic administration
-
Pepinsky RB, Shao Z, Ji B, et al. Exposure levels of anti-LINGO-1 Li81 antibody in the central nervous system and dose-efficacy relationships in rat spinal cord remyelination models after systemic administration. J Pharmacol Exp Ther 2011; 339: 519-529.
-
(2011)
J Pharmacol Exp Ther
, vol.339
, pp. 519-529
-
-
Pepinsky, R.B.1
Shao, Z.2
Ji, B.3
-
121
-
-
51249105318
-
Extracellular matrix of the central nervous system: from neglect to challenge
-
Zimmermann DR, Dours-Zimmermann MT. Extracellular matrix of the central nervous system: from neglect to challenge. Histochem Cell Biol 2008; 130: 635-653.
-
(2008)
Histochem Cell Biol
, vol.130
, pp. 635-653
-
-
Zimmermann, D.R.1
Dours-Zimmermann, M.T.2
-
122
-
-
0033215979
-
Matrix metalloproteinase-9/gelatinase B is required for process outgrowth by oligodendrocytes
-
Oh LY, Larsen PH, Krekoski CA, et al. Matrix metalloproteinase-9/gelatinase B is required for process outgrowth by oligodendrocytes. J Neurosci 1999; 19: 8464-8475.
-
(1999)
J Neurosci
, vol.19
, pp. 8464-8475
-
-
Oh, L.Y.1
Larsen, P.H.2
Krekoski, C.A.3
-
123
-
-
0346749451
-
Matrix metalloproteinase-9 facilitates remyelination in part by processing the inhibitory NG2 proteoglycan
-
Larsen PH, Wells JE, Stallcup WB, Opdenakker G, Yong VW. Matrix metalloproteinase-9 facilitates remyelination in part by processing the inhibitory NG2 proteoglycan. J Neurosci 2003; 23: 11127-11135.
-
(2003)
J Neurosci
, vol.23
, pp. 11127-11135
-
-
Larsen, P.H.1
Wells, J.E.2
Stallcup, W.B.3
Opdenakker, G.4
Yong, V.W.5
-
124
-
-
24744468983
-
Hyaluronan accumulates in demyelinated lesions and inhibits oligodendrocyte progenitor maturation
-
Back SA, Tuohy TM, Chen H, et al. Hyaluronan accumulates in demyelinated lesions and inhibits oligodendrocyte progenitor maturation. Nat Med 2005; 11: 966-972.
-
(2005)
Nat Med
, vol.11
, pp. 966-972
-
-
Back, S.A.1
Tuohy, T.M.2
Chen, H.3
-
125
-
-
77954893581
-
Hyaluronan blocks oligodendrocyte progenitor maturation and remyelination through TLR2
-
Sloane JA, Batt C, Ma Y, et al. Hyaluronan blocks oligodendrocyte progenitor maturation and remyelination through TLR2. Proc Natl Acad Sci U S A 2010; 107: 11555-11560.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 11555-11560
-
-
Sloane, J.A.1
Batt, C.2
Ma, Y.3
-
126
-
-
80052677773
-
The inhibitory effects of chondroitin sulfate proteoglycans on oligodendrocytes
-
Siebert JR, Osterhout DJ. The inhibitory effects of chondroitin sulfate proteoglycans on oligodendrocytes. J Neurochem 2011; 119: 176-188.
-
(2011)
J Neurochem
, vol.119
, pp. 176-188
-
-
Siebert, J.R.1
Osterhout, D.J.2
-
127
-
-
84867064116
-
Chondroitin sulfate proteoglycans in demyelinated lesions impair remyelination
-
Lau LW, Keough MB, Haylock-Jacobs S, et al. Chondroitin sulfate proteoglycans in demyelinated lesions impair remyelination. Ann Neurol 2012; 72: 419-432.
-
(2012)
Ann Neurol
, vol.72
, pp. 419-432
-
-
Lau, L.W.1
Keough, M.B.2
Haylock-Jacobs, S.3
-
128
-
-
0032411409
-
Degradation of chondroitin sulfate proteoglycan enhances the neurite-promoting potential of spinal cord tissue
-
Zuo J, Neubauer D, Dyess K, Ferguson TA, Muir D. Degradation of chondroitin sulfate proteoglycan enhances the neurite-promoting potential of spinal cord tissue. Exp Neurol 1998; 154: 654-662.
-
(1998)
Exp Neurol
, vol.154
, pp. 654-662
-
-
Zuo, J.1
Neubauer, D.2
Dyess, K.3
Ferguson, T.A.4
Muir, D.5
-
129
-
-
0037061426
-
Chondroitinase ABC promotes functional recovery after spinal cord injury
-
Bradbury EJ, Moon LD, Popat RJ, et al. Chondroitinase ABC promotes functional recovery after spinal cord injury. Nature 2002; 416: 636-640.
-
(2002)
Nature
, vol.416
, pp. 636-640
-
-
Bradbury, E.J.1
Moon, L.D.2
Popat, R.J.3
-
130
-
-
79961024760
-
Chondroitinase treatment following spinal contusion injury increases migration of oligodendrocyte progenitor cells
-
Siebert JR, Stelzner DJ, Osterhout DJ. Chondroitinase treatment following spinal contusion injury increases migration of oligodendrocyte progenitor cells. Exp Neurol 2011; 231: 19-29.
-
(2011)
Exp Neurol
, vol.231
, pp. 19-29
-
-
Siebert, J.R.1
Stelzner, D.J.2
Osterhout, D.J.3
-
131
-
-
37549049803
-
Inhibiting glycosaminoglycan chain polymerization decreases the inhibitory activity of astrocyte-derived chondroitin sulfate proteoglycans
-
Laabs TL, Wang H, Katagiri Y, et al. Inhibiting glycosaminoglycan chain polymerization decreases the inhibitory activity of astrocyte-derived chondroitin sulfate proteoglycans. J Neurosci 2007; 27: 14494-14501.
-
(2007)
J Neurosci
, vol.27
, pp. 14494-14501
-
-
Laabs, T.L.1
Wang, H.2
Katagiri, Y.3
-
132
-
-
1242314200
-
A novel DNA enzyme reduces glycosaminoglycan chains in the glial scar and allows microtransplanted dorsal root ganglia axons to regenerate beyond lesions in the spinal cord
-
Grimpe B, Silver J. A novel DNA enzyme reduces glycosaminoglycan chains in the glial scar and allows microtransplanted dorsal root ganglia axons to regenerate beyond lesions in the spinal cord. J Neurosci 2004; 24: 1393-1397.
-
(2004)
J Neurosci
, vol.24
, pp. 1393-1397
-
-
Grimpe, B.1
Silver, J.2
-
133
-
-
70350502060
-
PTPsigma is a receptor for chondroitin sulfate proteoglycan, an inhibitor of neural regeneration
-
Shen Y, Tenney AP, Busch SA, et al. PTPsigma is a receptor for chondroitin sulfate proteoglycan, an inhibitor of neural regeneration. Science 2009; 326: 592-596.
-
(2009)
Science
, vol.326
, pp. 592-596
-
-
Shen, Y.1
Tenney, A.P.2
Busch, S.A.3
-
134
-
-
80053624921
-
Leukocyte common antigen-related phosphatase is a functional receptor for chondroitin sulfate proteoglycan axon growth inhibitors
-
Fisher D, Xing B, Dill J, et al. Leukocyte common antigen-related phosphatase is a functional receptor for chondroitin sulfate proteoglycan axon growth inhibitors. J Neurosci 2011; 31: 14051-14066.
-
(2011)
J Neurosci
, vol.31
, pp. 14051-14066
-
-
Fisher, D.1
Xing, B.2
Dill, J.3
-
135
-
-
84860284042
-
NgR1 and NgR3 are receptors for chondroitin sulfate proteoglycans
-
Dickendesher TL, Baldwin KT, Mironova YA, et al. NgR1 and NgR3 are receptors for chondroitin sulfate proteoglycans. Nat Neurosci 2012; 15: 703-712.
-
(2012)
Nat Neurosci
, vol.15
, pp. 703-712
-
-
Dickendesher, T.L.1
Baldwin, K.T.2
Mironova, Y.A.3
-
136
-
-
84868660626
-
Review of the novelties presented at the 27th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) (II)
-
Fernandez O, Alvarez-Cermeno JC, Arroyo-Gonzalez R, et al. Review of the novelties presented at the 27th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) (II). Rev Neurol 2012; 54: 734-749.
-
(2012)
Rev Neurol
, vol.54
, pp. 734-749
-
-
Fernandez, O.1
Alvarez-Cermeno, J.C.2
Arroyo-Gonzalez, R.3
|