The uniqueness of being a neurotrophin receptor

Current Opinion in Neurobiology

Volumn 11, Issue 3, 2001, Pages 281-286

  Lee, Francis S ^a   Kim, Albert H ^b   Khursigara, Gus ^a   Chao, Moses V ^b  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; BRAIN DERIVED NEUROTROPHIC FACTOR; LIGAND; NERVE GROWTH FACTOR; NEUROTROPHIN 3; NEUROTROPHIN 4; NEUROTROPHIN RECEPTOR; PHOSPHOTRANSFERASE; PROTEIN P75 RECEPTOR; RECEPTOR; TROPOMYOSIN RELATED KINASE A; TROPOMYOSIN RELATED KINASE B; TROPOMYOSIN RELATED KINASE RECEPTOR; UNCLASSIFIED DRUG;

CELL COUNT; CELL DEATH; CELL FUNCTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; RECEPTOR BINDING; REVIEW; SIGNAL TRANSDUCTION; STRESS;

ANIMALS; ANTIGENS, CD; ANTIGENS, NEOPLASM; APOPTOSIS; CELL COUNT; DNA-BINDING PROTEINS; HUMANS; LIGANDS; MACROMOLECULAR SUBSTANCES; MEMBRANE PROTEINS; NEOPLASM PROTEINS; NERVE GROWTH FACTORS; NERVE TISSUE PROTEINS; NEURONS; PHOSPHOPROTEINS; RECEPTORS, NERVE GROWTH FACTOR; RECEPTORS, TUMOR NECROSIS FACTOR; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE II; SCHWANN CELLS; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0035369111     PISSN: 09594388     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-4388(00)00209-9     Document Type: Review

References (50)

1. The neurotrophin hypothesis for synaptic plasticity
2. Neurotrophins: Key regulators of cell fate and cell shape in the vertebrate nervous system
3. Neurotrophin signal transduction in the nervous system
4. The p75 neurotrophin receptor and neuronal apoptosis
5. Disruption of TrkB-mediated signaling induces disassembly of postsynaptic receptor clusters at neuromuscular junctions
6. The juxtamembrane region of MuSK has a critical role in agrin-mediated signaling
7. EphB receptors interact with NMDA receptors and regulate excitatory synapse formation
8. The TrkB-Shc site signals neuronal survival and local axon growth via MEK and PI3-kinase
9. The signaling adapter FRS-2 competes for Shc for binding to the nerve growth factor receptor TrkA
10. Identification and characterization of novel substrates of Trk receptors in developing neurons
11. Down-regulation of the neurotrophin TrkB following ligand binding
12. Biochemical and functional interactions between the neurotrophin receptors Trk and p75NTR
13. Neurotrophin receptor structure and interactions
14. Differential expression of nerve growth factor receptors leads to altered binding affinity and neurotrophin responsiveness
15. The p75 neurotrophin receptor influences NT responsiveness of sympathetic neurons in vivo
16. NMR structure of the death domain of the p75 neurotrophin receptor
17. Neuronal life and death decisions: Functional antagonism between the Trk and p75 neurotrophin receptors
18. p75 neurotrophin receptor as a modulator of survival and death decisions
19. p75 neurotrophin receptor signaling: Mechanisms for neurotrophic modulation of cell stress?
20. p75 neurotrophin receptor-mediated neuronal death is promoted by Bcl-2 and prevented by Bcl-xL
21. Chopper, a new death domain of the p75 neurotrophin receptor that mediates rapid neuronal cell death
22. Oligodendrocyte apoptosis mediated by caspase activation
23. A comparison of the cytoplasmic domains of the fas receptor and the p75 neurotrophin receptor
24. p75 neurotrophin receptor expression is induced in apoptotic neurons after seizure
25. Upregulated p75NTR neurotrophin receptor on glial cells in MS plaques
26. NG2-positive oligodendrocyte progenitor cells in adult human brain and multiple sclerosis lesions
27. p75 is important for axon growth and Schwann cell migration during development
28. Induction of postnatal Schwann cell death by the low-affinity neurotrophin receptor in vitro and after axotomy
29. Nerve growth factor activation of nuclear factor κB through its p75 receptor is an anti-apoptotic signal in RN22 schwannoma cells
30. The p75 neurotrophin receptor mediates neuronal apoptosis and is essential for naturally occurring sympathetic neuron death
31. Attenuation of a caspase-3 dependent cell death in NT-4 and p75- deficient embryonic sensory neurons
32. Leukemia inhibitory factor requires concurrent p75LNTR signaling to induce apoptosis of cultured sympathetic neurons
33. Co-induction of p75NTR and p75NTR-associated death executor in neurons after zinc exposure in cortical culture or transient ischemia in the rat
34. Low-affinity nerve-growth factor receptor (p75NTR) can serve as a receptor for rabies virus
35. Experimental rabies virus infection of p75 neurotrophin receptor-deficient mice
36. An evolutionarily conserved transmembrane protein that is a novel downstream target of neurotrophin and ephrin receptors
37. The zinc finger protein NRIF interacts with the neurotrophin receptor p75(NTR) and participates in programmed cell death
38. NADE, a p75NTR-associated cell death executor, is involved in signal transduction mediated by the common neurotrophin receptor p75NTR
39. NRAGE, a novel MAGE protein, interacts with the p75 neurotrophin receptor and facilitates nerve growth factor-dependent apoptosis
40. Neurotrophin binding to the p75 receptor modulates Rho activity and axonal outgrowth
41. Identification of a zinc finger protein whose subcellular distribution is regulated by serum and nerve growth factor
42. Association of tyrosine kinase neurotrophin receptors with components of the cytoplasmic dynein motor
43. GIPC and GAIP form a complex with TrkA: A putative link between G-protein and receptor tyrosine kinase pathways
44. Brain-derived neurotrophic factor-deficient mice develop aggressiveness and hyperphagia in conjunction with brain serotonergic abnormalities
45. Central neuronal loss and behavioral impairment in mice lacking neurotrophin receptor p75
46. Association of the Abl tyrosine kinase with the Trk nerve growth factor receptor
47. Direct interaction of nerve growth factor receptor, TrkA, with non-receptor tyrosine kinase, c-Abl, through the activation loop
48. Association of the p75 neurotrophin receptor with TRAF6
49. TRAF family proteins interact with the common neurotrophin receptor and modulate apoptosis induction
50. Functional interaction of Fas-associated phosphatase-1 (FAP-1) with p75(NTR) and their effect on NF-κB activation