Expression of the low-affinity neurotrophin receptor, p75NTR, is upregulated by oligodendroglial progenitors adjacent to the subventricular zone in response to demyelination

GLIA

Volumn 48, Issue 1, 2004, Pages 64-75

  Petratos, Steven ^a   Gonzales, Michael F ^b   Azari, Michael F ^a,c   Marriott, Mark ^a   Minichiello, Rebecca A ^a   Shipham, Kylie A ^a   Profyris, Christos ^a,c   Nicolaou, Antonis ^c   Boyle, Kristy ^a,c   Cheema, Surindar S ^a,c   Kilpatrick, Trevor J ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b ROYAL MELBOURNE HOSPITAL   (Australia)

^c MONASH UNIVERSITY   (Australia)

Author keywords

Apoptosis; Chondroitin sulfate proteoglycan NG2; Chronic demyelination; Low affinity neurotrophin receptor; Multiple sclerosis; Oligodendroglial progenitor cells

Indexed keywords

NEUROTROPHIN RECEPTOR; PROTEIN P75; CARRIER PROTEIN; CHELATING AGENT; CUPRIZONE; GROWTH FACTOR RECEPTOR; NERVE GROWTH FACTOR RECEPTOR; NERVE PROTEIN; NGFR PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BRAIN REGION; CELL POPULATION; CONTROLLED STUDY; DEMYELINATION; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; MOLECULAR MECHANICS; MOUSE; MULTIPLE SCLEROSIS; NEUROPATHOLOGY; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR BINDING; RECEPTOR UPREGULATION; STEM CELL; WHITE MATTER; ADULT; AGED; ANIMAL; BIOSYNTHESIS; BRAIN; BRAIN LEVEL; C57BL MOUSE; CELL DEATH; CYTOLOGY; DEMYELINATING DISEASE; IMAGE PROCESSING; IMMUNOHISTOCHEMISTRY; MALE; METABOLISM; MIDDLE AGED; NICK END LABELING; PHENOTYPE; PHYSIOLOGY; TISSUE FIXATION; UPREGULATION;

ADULT; AGED; AGED, 80 AND OVER; ANIMALS; BRAIN; BRAIN CHEMISTRY; CARRIER PROTEINS; CELL DEATH; CHELATING AGENTS; CUPRIZONE; DEMYELINATING DISEASES; FEMALE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; MALE; MICE; MICE, INBRED C57BL; MIDDLE AGED; MULTIPLE SCLEROSIS; NERVE TISSUE PROTEINS; OLIGODENDROGLIA; PHENOTYPE; RECEPTORS, GROWTH FACTOR; RECEPTORS, NERVE GROWTH FACTOR; STEM CELLS; TISSUE FIXATION; UP-REGULATION;

EID: 6044247624     PISSN: 08941491     EISSN: None     Source Type: Journal    
DOI: 10.1002/glia.20056     Document Type: Article

References (22)

1. Anton ES, Weskamp G, Reichardt LF, Matthew WD. 1994. Nerve growth factor and its low-affinity receptor promote Schwann cell migration. Proc Natl Acad Sci USA 91:2795-2799.
2. Arnett HA, Mason J, Marino M, Suzuki K, Matsushima GK, Ting JP. 2001. TNF alpha promotes proliferation of oligodendrocyte progenitors and remyelination. Nat Neurosci 4:1116-1122.
3. Back SA, Luo NL, Borenstein NS, Volpe JJ, Kinney HC. 2002. Arrested oligodendrocyte lineage progression during human cerebral white matter development: dissociation between the timing of progenitor differentiation and myelinogenesis. J Neuropathol Exp Neurol 61:197-211.
4. Beattie MS, Harrington AW, Lee R, Kim JY, Boyce SL, Longo FM, Bresnahan JC, Hempstead BL, Yoon SO. 2002. ProNGF induces p75-mediated death of oligodendrocytes following spinal cord injury. Neuron 36:375-386.
5. Bentley CA, Lee KF. 2000. p75 is important for axon growth and Schwann cell migration during development. J Neurosci 20:7706-7715.
6. Bonetti B, Stegagno C, Cannella B, Rizzuto N, Moretto G, Raine CS. 1999. Activation of NF-kappaB and c-jun transcription factors in multiple sclerosis lesions. Implications for oligodendrocyte pathology. Am J Pathol 155:1433-1438.
7. Calza L, Giardino L, Pozza M, Bettelli C, Micera A, Aloe L. 1998. Proliferation and phenotype regulation in the subventricular zone during experimental allergic encephalomyelitis: in vivo evidence of a role for nerve growth factor. Proc Natl Acad Sci USA 95:3209-3214.
8. Calza L, Fernandez M, Giuliani A, Aloe L, Giardino L. 2002. Thyroid hormone activates oligodendrocyte precursors and increases a myelin-forming protein and NGF content in the spinal cord during experimental allergic encephalomyelitis. Proc Natl Acad Sci USA 99:3258-3263.
9. Casaccia-Bonnefil P, Carter BD, Dobrowsky RT, Chao MV. 1996. Death of oligodendrocytes mediated by the interaction of nerve growth factor with its receptor p75. Nature 383:716-719.
10. Chang A, Nishiyama A, Peterson J, Prineas J, Trapp BD. 2000. NG2-positive oligodendrocyte progenitor cells in adult human brain and multiple sclerosis lesions. J Neurosci 20:6404-6412.
11. Chang A, Tourtellotte WW, Rudick R, Trapp BD. 2002. Premyelinating oligodendrocytes in chronic lesions of multiple sclerosis. N Engl J Med 346:165-173.
12. Dowling P, Ming X, Raval S, Husar W, Casaccia-Bonnefil P, Chao M, Cook S, Blumberg B. 1999. Up-regulated p75NTR neurotrophin receptor on glial cells in MS plaques. Neurology 53:1676-1682.
13. Gu C, Casaccia-Bonnefil P, Srinivasan A, Chao MV. 1999. Oligodendrocyte apoptosis mediated by caspase activation. J Neurosci 19: 3043-3049.
14. Kleihues P, Burger PC, Scheithauer BW. 1993. Histological typing of tumours of the central nervous system. WHO international classification of tumours. 2nd ed. New York: Springer-Verlag.
15. Ladiwala U, Lachance C, Simoneau SJ, Bhakar A, Barker PA, Antel JP. 1998. p75 neurotrophin receptor expression on adult human oligodendrocytes: signaling without cell death in response to NGF. J Neurosci 18:1297-1304.
16. Lucchinetti C, Bruck W, Parisi J, Scheithauer B, Rodriguez M, Lassmann H. 2000. Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination. Ann Neurol 47:707-717.
17. Nishiyama A, Lin XH, Giese N, Heldin CH, Stallcup WB. 1996. Co-localization of NG2 proteoglycan and PDGF alpha-receptor on O2A progenitor cells in the developing rat brain. J Neurosci Res 43:299-314.
18. + glial cells: a novel glial cell population in the adult brain. J Neuropathol Exp Neurol 58: 1113-1124.
19. Syroid DE, Maycox PR, Burrola PG, Liu N, Wen D, Lee KF, Lemke G, Kilpatrick TJ. 1996. Cell death in the Schwann cell lineage and its regulation by neuregulin. Proc Natl Acad Sci USA 93:9229-9234.
20. Syroid DE, Maycox PJ, Soilu-Hanninen M, Petratos S, Bucci T, Burrola P, Murray S, Cheema S, Lee KF, Lemke G, Kilpatrick TJ. 2000. Induction of postnatal Schwann cell death by the low-affinity neurotrophin receptor in vitro and after axotomy. J Neurosci 20:5741-5747.
21. Watanabe M, Toyama Y, Nishiyama A. 2002. Differentiation of proliferated NG2-positive glial progenitor cells in a remyelinating lesion. J Neurosci Res 69:826-836.
22. Yoon SO, Casaccia-Bonnefil P, Carter B, Chao MV. 1998. Competitive signaling between TrkA and p75 nerve growth factor receptors determines cell survival. J Neurosci 18:3273-3281.