Amelioration of experimental autoimmune encephalomyelitis by curcumin treatment through inhibition of IL-17 production

International Immunopharmacology

Volumn 9, Issue 5, 2009, Pages 575-581

  Xie, Lin ^a,b,d   Li, Xiao Kang ^a   Funeshima Fuji, Naoko ^a   Kimura, Hiromitsu ^a   Matsumoto, Yoh ^c   Isaka, Yoshitaka ^b   Takahara, Shiro ^b  

^a NATIONAL RESEARCH INSTITUTE FOR CHILD HEALTH AND DEVELOPMENT   (Japan)

^b OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^d WENZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Curcumin; Cytokine; Experimental autoimmune encephalomyelitis; IL 17; Lymphocyte; Multiple sclerosis

Indexed keywords

CURCUMIN; CYTOKINE; INTERLEUKIN 17; INTERLEUKIN 21; INTERLEUKIN 6; MESSENGER RNA; PROTEIN ROR GAMMA T; RECEPTOR PROTEIN; STAT3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; FREUND ADJUVANT; INTERLEUKIN DERIVATIVE; MYELIN BASIC PROTEIN; PEPTIDE; RETINOID RELATED ORPHAN RECEPTOR GAMMA;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE SEVERITY; DOSE RESPONSE; DOWN REGULATION; DRUG EFFICACY; DRUG MECHANISM; FEMALE; GENE EXPRESSION; HELPER CELL; INFLAMMATORY INFILTRATE; LEWIS RAT; LYMPHOCYTE PROLIFERATION; MULTIPLE SCLEROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SPINAL CORD; ANIMAL; CELL PROLIFERATION; CHEMISTRY; CURCUMA; DISEASE COURSE; DRUG EFFECTS; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; GENETICS; GUINEA PIG; HUMAN; IMMUNIZATION; IMMUNOLOGY; JURKAT CELL LINE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHOSPHORYLATION; PHYTOTHERAPY; RHIZOME;

ANIMALS; CELL PROLIFERATION; CURCUMA; CURCUMIN; DISEASE PROGRESSION; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; FREUND'S ADJUVANT; GUINEA PIGS; HUMANS; IMMUNIZATION; INTERLEUKIN-17; INTERLEUKIN-6; INTERLEUKINS; JURKAT CELLS; MULTIPLE SCLEROSIS; MYELIN BASIC PROTEINS; NUCLEAR RECEPTOR SUBFAMILY 1, GROUP F, MEMBER 3; PEPTIDES; PHOSPHORYLATION; PHYTOTHERAPY; RATS; RATS, INBRED LEW; RHIZOME; SPINAL CORD; STAT3 TRANSCRIPTION FACTOR; T-LYMPHOCYTES, HELPER-INDUCER; TRANSFORMING GROWTH FACTOR BETA; MYELIN BASIC PROTEIN;

EID: 63549122337     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2009.01.025     Document Type: Article

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