Brain-derived neurotrophic factor gene delivery in an animal model of multiple sclerosis using bone marrow stem cells as a vehicle

Journal of Neuroimmunology

Volumn 210, Issue 1-2, 2009, Pages 40-51

  Makar, Tapas K ^a,b,c   Bever, Christopher T ^a,b,c   Singh, Ishwar S ^a,c   Royal, Walter ^a,b,c   Sahu, Surasri Nandan ^c   Sura, Tushar P ^a,c   Sultana, Shireen ^a,c   Sura, Karna T ^a,c   Patel, Niraj ^a,c   Dhib Jalbut, Suhayl ^d   Trisler, David ^a,b,c  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b VA Multiple Sclerosis Center of Excellence East   (United States)

^c UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^d ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

BDNF; Bone marrow stem cell; EAE; Gene therapy; MS; Transplantation

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 11; INTERLEUKIN 4; PROTEOLIPID PROTEIN; PROTEOLIPID PROTEIN 139-151; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ALLERGIC ENCEPHALITIS; ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DEMYELINATION; DISEASE SEVERITY; EXPERIMENTAL MODEL; EXPERIMENTAL MOUSE; FEMALE; GENE DELIVERY SYSTEM; GENE TARGETING; GENETIC ENGINEERING; GENETIC TRANSFECTION; HEMATOPOIETIC STEM CELL; HISTOPATHOLOGY; MOUSE; MULTIPLE SCLEROSIS; NONHUMAN; PRIORITY JOURNAL; REMYELINIZATION; SWISS JAMES LAMBERT MOUSE;

ANIMALS; BONE MARROW TRANSPLANTATION; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELLS, CULTURED; CYTOKINES; DISEASE MODELS, ANIMAL; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; GENE EXPRESSION REGULATION; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; MICE; MYELIN PROTEOLIPID PROTEIN; MYELIN SHEATH; PEPTIDE FRAGMENTS; TREATMENT OUTCOME;

EID: 67349175764     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2009.02.017     Document Type: Article

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