Transcriptional therapy with the histone deacetylase inhibitor trichostatin A ameliorates experimental autoimmune encephalomyelitis

Journal of Neuroimmunology

Volumn 164, Issue 1-2, 2005, Pages 10-21

  Camelo, Sandra ^a   Iglesias, Antonio H ^a   Hwang, Daehee ^b   Due, Brice ^c   Ryu, Hoon ^d,e   Smith, Karen ^d,e   Gray, Steven G ^a   Imitola, Jaime ^a   Duran, German ^a   Assaf, Basel ^a   Langley, Brett ^a   Khoury, Samia J ^a   Stephanopoulos, George ^b   De Girolami, Umberto ^c   Ratan, Rajiv R ^a   Ferrante, Robert J ^d,e   Dangond, Fernando ^a,c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b Massachusetts Institute of Technology Cambridge   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

^e BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Experimental autoimmune encephalomyelitis; Histone deacetylase; Microarrays; Multiple sclerosis; Trichostatin A

Indexed keywords

ANTIOXIDANT; CASPASE; HISTONE DEACETYLASE INHIBITOR; MESSENGER RNA; TRANSCRIPTION FACTOR E2F; TRICHOSTATIN A;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL LOSS; CONTROLLED STUDY; DEMYELINATION; DISEASE COURSE; DISEASE MODEL; DOWN REGULATION; ENZYME ACTIVATION; ENZYME INHIBITION; FETUS; MOUSE; MULTIPLE SCLEROSIS; NERVE CELL; NERVE CELL DIFFERENTIATION; NERVE CELL GROWTH; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; SPINAL CORD; SPLEEN CELL; TH1 CELL; UPREGULATION;

ANIMALS; CELL DEATH; CELLS, CULTURED; CEREBRAL CORTEX; CYTOKINES; DISEASE MODELS, ANIMAL; DRUG ADMINISTRATION SCHEDULE; DRUG INTERACTIONS; EMBRYO; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GLYCOPROTEINS; HYDROXAMIC ACIDS; IMMUNOHISTOCHEMISTRY; MICE; MICE, INBRED C57BL; NEURONS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PEPTIDE FRAGMENTS; PROTEIN SYNTHESIS INHIBITORS; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SEVERITY OF ILLNESS INDEX; SPLEEN; TETRAZOLIUM SALTS; THIAZOLES; TIME FACTORS;

EID: 20444446595     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2005.02.022     Document Type: Article

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