Central nervous system rather than immune cell-derived BDNF mediates axonal protective effects early in autoimmune demyelination

Acta Neuropathologica

Volumn 123, Issue 2, 2012, Pages 247-258

  Lee, De Hyung ^a,b   Geyer, Eva ^c   Flach, Anne Christine ^c   Jung, Klaus ^c   Gold, Ralf ^b   Flügel, Alexander ^c   Linker, Ralf A ^a,b   Lühder, Fred ^c  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b ST JOSEF HOSPITAL   (Germany)

^c UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

Author keywords

BDNF; Conditional knock out mice; EAE; Neuroimmunology; Neurotrophins

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; GLATIRAMER;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AXONAL INJURY; BONE MARROW CELL; CELL INFILTRATION; CONTROLLED STUDY; DISEASE COURSE; DISEASE SEVERITY; DRUG EFFICACY; GENE DELETION; GENE EXPRESSION REGULATION; IMMUNE RESPONSE GENE; IMMUNOCOMPETENT CELL; MOTOR DYSFUNCTION; MOUSE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; AXONS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CENTRAL NERVOUS SYSTEM; DISEASE MODELS, ANIMAL; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NERVE DEGENERATION; PRIMARY CELL CULTURE; RADIATION CHIMERA;

EID: 84857030341     PISSN: 00016322     EISSN: 14320533     Source Type: Journal    
DOI: 10.1007/s00401-011-0890-3     Document Type: Article

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