The neurotrophin receptor p75NTR as a positive modulator of myelination

Science

Volumn 298, Issue 5596, 2002, Pages 1245-1248

  Cosgaya, José M ^a   Chan, Jonah R ^a   Shooter, Eric M ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN; CELLS;

MYELINATION;

NEUROLOGY;

BRAIN DERIVED NEUROTROPHIC FACTOR; MYELIN; NEUROTROPHIN RECEPTOR; PROTEIN P75; PROTEIN TYROSINE KINASE; TYROSINE KINASE RECEPTOR; ANTIBODY; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; MYELIN ASSOCIATED GLYCOPROTEIN; MYELIN PROTEIN; NERVE GROWTH FACTOR RECEPTOR; NEUROTROPHIN 3; NEUROTROPHIN 3 RECEPTOR;

BIOLOGY; NERVOUS SYSTEM DISORDER;

ANIMAL CELL; ARTICLE; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION; MYELINATION; NERVE REGENERATION; NONHUMAN; PERIPHERAL NERVOUS SYSTEM; PRIORITY JOURNAL; PROTEIN FUNCTION; SCHWANN CELL; ANIMAL; BIOLOGICAL MODEL; COCULTURE; CYTOLOGY; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; METABOLISM; MOUSE; MYELIN SHEATH; NERVE FIBER; PHYSIOLOGY; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCIATIC NERVE; SIGNAL TRANSDUCTION; SPINAL GANGLION; SPRAGUE DAWLEY RAT;

ANIMALS; ANTIBODIES; AXONS; BRAIN-DERIVED NEUROTROPHIC FACTOR; COCULTURE TECHNIQUES; GANGLIA, SPINAL; IMMUNOHISTOCHEMISTRY; MICE; MODELS, NEUROLOGICAL; MYELIN P0 PROTEIN; MYELIN SHEATH; MYELIN-ASSOCIATED GLYCOPROTEIN; NEUROTROPHIN 3; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, NERVE GROWTH FACTOR; RECEPTOR, TRKB; RECEPTOR, TRKC; RECEPTORS, NERVE GROWTH FACTOR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SCHWANN CELLS; SCIATIC NERVE; SIGNAL TRANSDUCTION;

EID: 0037044576     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1076595     Document Type: Article

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23. We thank Regeneron Pharmaceuticals, L. Reichardt, A. Welcher, and J. Archelos for reagents and antibodies; N. Ghori for expertise with electron microscopy; and B. Barres for critical reading of the manuscript. Supported by grants from NIH (NS04270), the Muscular Dystrophy Association, and the McGowan Charitable Trust (E.M.S.).