Targeted retrograde gene delivery of brain-derived neurotrophic factor suppresses apoptosis of neurons and oligodendroglia after spinal cord injury in rats

Spine

Volumn 35, Issue 5, 2010, Pages 497-504

  Nakajima, Hideaki ^a   Uchida, Kenzo ^a   Yayama, Takafumi ^a   Kobayashi, Shigeru ^a   Guerrero, Alexander Rodriguez ^a   Furukawa, Shoei ^b   Baba, Hisatoshi ^a  

^a UNIVERSITY OF FUKUI   (Japan)

^b GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Adenoviral vector (AdV); Apoptosis; Brain derived neurotrophic factor (BDNF); Retrograde gene transfer; Spinal cord injury

Indexed keywords

ADENOVIRUS VECTOR; BETA GALACTOSIDASE; BRAIN DERIVED NEUROTROPHIC FACTOR; CASPASE 3; CELL MARKER; NEURON SPECIFIC NUCLEAR PROTEIN;

ADENOVIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CERVICAL SPINE; CONTROLLED STUDY; DOWN REGULATION; GENE IDENTIFICATION; GENE TARGETING; GENETIC TRANSFECTION; GLIA CELL; HISTOPATHOLOGY; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; IN VIVO GENE TRANSFER; INJECTION; MALE; MARKER GENE; MOTONEURON; NERVE CELL; NEUROPROTECTION; NICK END LABELING; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; SPINAL CORD INJURY; STERNOCLEIDOMASTOID MUSCLE; VIRAL GENE DELIVERY SYSTEM; WHITE MATTER;

ADENOVIRIDAE; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; BRAIN-DERIVED NEUROTROPHIC FACTOR; CERVICAL VERTEBRAE; GENE THERAPY; GENETIC VECTORS; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; MALE; NEURONS; OLIGODENDROGLIA; RATS; RATS, SPRAGUE-DAWLEY; SPINAL CORD INJURIES; STATISTICS, NONPARAMETRIC;

EID: 77649283854     PISSN: 03622436     EISSN: 15281159     Source Type: Journal    
DOI: 10.1097/BRS.0b013e3181b8e89b     Document Type: Article

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