Changed histone acetylation patterns in normal-appearing white matter and early multiple sclerosis lesions

Journal of Neuroscience

Volumn 31, Issue 9, 2011, Pages 3435-3445

  Pedre, Xiomara ^a   Mastronardi, Fabrizio ^b   Bruck, Wolfgang ^c   López Rodas, Gerardo ^a,d   Kuhlmann, Tanja ^e   Casaccia, Patrizia ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b Inception Research and Therapeutics ^*  (Canada)

^c UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^d UNIVERSITY OF VALENCIA   (Spain)

^e UNIVERSITY HOSPITAL MÜNSTER   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE ACETYLTRANSFERASE; HISTONE ACETYLTRANSFERASE PCAF; HISTONE H3; INHIBITOR OF DIFFERENTIATION 2; PROTEIN NOGO A; PROTEIN P300; TRANSCRIPTION FACTOR 7 LIKE 2; TRANSCRIPTION FACTOR SOX2;

ADULT; AGED; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE DURATION; FEMALE; FRONTAL LOBE; GENE TARGETING; HISTONE ACETYLATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOREACTIVITY; MALE; MULTIPLE SCLEROSIS; NERVE CELL DIFFERENTIATION; NUCLEOTIDE SEQUENCE; OLIGODENDROGLIA; PRIORITY JOURNAL; PROMOTER REGION; WHITE MATTER;

ACETYLATION; ADULT; AGED; AGED, 80 AND OVER; EARLY DIAGNOSIS; FEMALE; HISTONE ACETYLTRANSFERASES; HISTONES; HUMANS; MALE; MIDDLE AGED; MULTIPLE SCLEROSIS; NERVE FIBERS, MYELINATED; YOUNG ADULT;

EID: 79952272438     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4507-10.2011     Document Type: Article

References (44)

1. Arnett HA, Wang Y, Matsushima GK, Suzuki K, Ting JP (2003) Functional genomic analysis of remyelination reveals importance of inflammation in oligodendrocyte regeneration 2. J Neurosci 23:9824-9832. (Pubitemid 37371596)
2. Bachelin C, Zujovic V, Buchet D, Mallet J, Baron-Van Evercooren A (2010) Ectopic expression of polysialylated neural cell adhesion molecule in adult macaque Schwann cells promotes their migration and remyelination potential in the central nervous system. Brain 133:406-420.
3. Bieber AJ, Kerr S, Rodriguez M (2003) Efficient central nervous system remyelination requires T cells. Ann Neurol 53:680-684. (Pubitemid 36529446)
4. Brück W, Porada P, Poser S, Rieckmann P, Hanefeld F, Kretzschmar HA, Lassmann H (1995) Monocyte/macrophage differentiation in early multiple sclerosis lesions. Ann Neurol 38:788-796.
5. Chang A, Tourtellotte WW, Rudick R, Trapp BD (2002) Premyelinating oligodendrocytes in chronic lesions of multiple sclerosis. N Engl J Med 346:165-173. (Pubitemid 34438882)
6. Charles P, Hernandez MP, Stankoff B, Aigrot MS, Colin C, Rougon G, Zalc B, Lubetzki C (2000) Negative regulation of central nervous system myelination by polysialylated-neural cell adhesion molecule. Proc Natl Acad Sci U S A 97:7585-7590. (Pubitemid 30431507)
7. Copray S, Huynh JL, Sher F, Casaccia-Bonnefil P, Boddeke E (2009) Epigenetic mechanisms facilitating oligodendrocyte development, maturation, and aging. Glia 57:1579-1587.
8. Cunliffe VT, Casaccia-Bonnefil P (2006) Histone deacetylase 1 is essential for oligodendrocyte specification in the zebrafish CNS. Mech Dev 123:24-30. (Pubitemid 43031354)
9. Fancy SP, Baranzini SE, Zhao C, Yuk DI, Irvine KA, Kaing S, Sanai N, Franklin RJ, Rowitch DH (2009) Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS. Genes Dev 23:1571-1585.
10. Frischer JM, Bramow S, Dal-Bianco A, Lucchinetti CF, Rauschka H, Schmidbauer M, Laursen H, Sorensen PS, Lassmann H (2009) The relation between inflammation and neurodegeneration in multiple sclerosis brains. Brain 132:1175-1189.
11. Goldschmidt T, Antel J, König FB, Brück W, Kuhlmann T (2009) Remyelination capacity of the MS brain decreases with disease chronicity. Neurology 72:1914-1921.
12. Graumann U, Reynolds R, Steck AJ, Schaeren-Wiemers N (2003) Molecular changes in NAWM in multiple sclerosis are characteristic of neuroprotective mechanisms against hypoxic insult. Brain Pathol 13:554-573. (Pubitemid 37420699)
13. He Y, Dupree J, Wang J, Sandoval J, Li J, Liu H, Shi Y, Nave KA, Casaccia-Bonnefil P (2007) The transcription factor Yin Yang 1 is essential for oligodendrocyte progenitor differentiation. Neuron 55:217-230. (Pubitemid 47048909)
14. Hsieh J, Nakashima K, Kuwabara T, Mejia E, Gage FH (2004) Histone deacetylase inhibition-mediated neuronal differentiation of multipotent adult neural progenitor cells. Proc Natl Acad Sci U S A 101:16659-16664. (Pubitemid 39557769)
15. Huynh JL, Casaccia P (2010) Defining the chromatin landscape in demyelinating disorders. Neurobiol Dis 39:47-52.
16. Ito K, Barnes PJ (2009) COPD as a disease of accelerated lung aging. Chest 135:173-180.
17. John GR, Shankar SL, Shafit-Zagardo B, Massimi A, Lee SC, Raine CS, Brosnan CF (2002) Multiple sclerosis: re-expression of a developmental pathway that restricts oligodendrocyte maturation. Nat Med 8:1115-1121. (Pubitemid 35175966)
18. Kotter MR, Zhao C, van Rooijen N, Franklin RJ (2005) Macrophage-depletion induced impairment of experimental CNS remyelination is associated with a reduced oligodendrocyte progenitor cell response and altered growth factor expression. Neurobiol Dis 18:166-175. (Pubitemid 40092906)
19. Kouzarides T (2007) Chromatin modifications and their function. Cell 128:693-705.
20. Kuhlmann T, Miron V, Cuo Q, Wegner C, Antel J, Brück W (2008) Differentiation block of oligodendroglial progenitor cells as a cause for remyelination failure in chronic multiple sclerosis. Brain 131:1749-1758. (Pubitemid 351957453)
21. Kutzelnigg A, Lucchinetti CF, Stadelmann C, Brück W, Rauschka H, Bergmann M, Schmidbauer M, Parisi JE, Lassmann H (2005) Cortical demyelination and diffuse white matter injury in multiple sclerosis. Brain 128:2705-2712. (Pubitemid 41552953)
22. Li H, He Y, Richardson WD, Casaccia P (2009) Two-tier transcriptional control of oligodendrocyte differentiation. Curr Opin Neurobiol 19:479-485.
23. Liu A, Han YR, Li J, Sun D, Ouyang M, Plummer MR, Casaccia-Bonnefil P (2007) The glial or neuronal fate choice of oligodendrocyte progenitors is modulated by their ability to acquire an epigenetic memory. J Neurosci 27:7339-7343. (Pubitemid 47037547)
24. Liu H, Hu Q, D'ercole AJ, Ye P (2009) Histone deacetylase 11 regulates oligodendrocyte-specific gene expression and cell development in OL-1 oligodendroglia cells. Glia 57:1-12.
25. Liu J, Casaccia P (2010) Epigenetic regulation of oligodendrocyte identity. Trends Neurosci 33:193-201.
26. Louro R, Nakaya HI, Amaral PP, Festa F, Sogayar MC, da Silva AM, Verjovski-Almeida S, Reis EM (2007) Androgen responsive intronic non-coding RNAs. BMC Biol 5:4.
27. Marin-Husstege M, Muggironi M, Liu A, Casaccia-Bonnefil P (2002) Histone deacetylase activity is necessary for oligodendrocyte lineage progression. J Neurosci 22:10333-10345. (Pubitemid 35416871)
28. Mastronardi FG, Wood DD, Mei J, Raijmakers R, Tseveleki V, Dosch HM, Probert L, Casaccia-Bonnefil P, Moscarello MA (2006) Increased citrullination of histone H3 in multiple sclerosis brain and animal models of demyelination: a role for tumor necrosis factor-induced peptidylarginine deiminase 4 translocation. J Neurosci 26:11387-11396. (Pubitemid 44772168)
29. Mi S, Miller RH, Lee X, Scott ML, Shulag-Morskaya S, Shao Z, Chang J, Thill G, Levesque M, Zhang M, Hession C, Sah D, Trapp B, He Z, Jung V, McCoy JM, Pepinsky RB (2005) LINGO-1 negatively regulates myelination by oligodendrocytes. Nat Neurosci 8:745-751. (Pubitemid 43085840)
30. Mi S, Hu B, Hahm K, Luo Y, Kam Hui ES, Yuan Q, Wong WM, Wang L, Su H, Chu TH, Guo J, Zhang W, So KF, Pepinsky B, Shao Z, Graff C, Garber E, Jung V, Wu EX, Wu W (2007) LINGO-1 antagonist promotes spinal cord remyelination and axonal integrity in MOG-induced experimental autoimmune encephalomyelitis. Nat Med 13:1228-1233. (Pubitemid 47530642)
31. Narayanan R, Jiang J, Gusev Y, Jones A, Kearbey JD, Miller DD, Schmittgen TD, Dalton JT (2010) MicroRNAs are mediators of androgen action in prostate and muscle. PLoS One 5:e13637.
32. Patrikios P, Stadelmann C, Kutzelnigg A, Rauschka H, Schmidbauer M, Laursen H, Sorensen PS, Brück W, Lucchinetti C, Lassmann H (2006) Remyelination is extensive in a subset of multiple sclerosis patients. Brain 129:3165-3172. (Pubitemid 44871433)
33. Pfaffl MW (2001) A new mathematical model for relative quantification real-time RT-PCR. Nucleic Acids Res 29:e45.
34. Samanta J, Kessler JA (2004) Interactions between ID and OLIG proteins mediate the inhibitory effects of BMP4 on oligodendroglial differentiation. Development 131:4131-4142. (Pubitemid 39276185)
35. Shen S, Li J, Casaccia-Bonnefil P (2005) Histone modifications affect timing of oligodendrocyte progenitor differentiation in the developing rat brain. J Cell Biol 169:577-589. (Pubitemid 41002851)
36. Shen S, Liu A, Li J, Wolubah C, Casaccia-Bonnefil P (2008a) Epigenetic memory loss in aging oligodendrocytes in the corpus callosum. Neurobiol Aging 29:452-463. (Pubitemid 351215588)
37. Shen S, Sandoval J, Swiss VA, Li J, Dupree J, Franklin RJ, Casaccia-Bonnefil P (2008b) Age-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiency. Nat Neurosci 11:1024-1034.
38. Sim FJ, Zhao C, Penderis J, Franklin RJ (2002) The age-related decrease in CNS remyelination efficiency is attributable to an impairment of both oligodendrocyte progenitor recruitment and differentiation. J Neurosci 22:2451-2459. (Pubitemid 37465793)
39. Sim FJ, Lang JK, Waldau B, Roy NS, Schwartz TE, Pilcher WH, Chandross KJ, Natesan S, Merrill JE, Goldman SA (2006) Complementary patterns of gene expression by human oligodendrocyte progenitors and their environment predict determinants of progenitor maintenance and differentiation. Ann Neurol 59:763-779. (Pubitemid 43673154)
40. Wang S, Sdrulla AD, diSibio G, Bush G, Nofziger D, Hicks C, Weinmaster G, Barres BA (1998) Notch receptor activation inhibits oligodendrocyte differentiation. Neuron 21:63-75. (Pubitemid 28355692)
41. Wolswijk G (1998) Chronic stage multiple sclerosis lesions contain a relatively quiescent population of oligodendrocyte precursor cells. J Neurosci 18:601-609.
42. Yamagata K, Fujiyama S, Ito S, Ueda T, Murata T, Naitou M, Takeyama K, Minami Y, O'Malley BW, Kato S (2009) Maturation of microRNA is hormonally regulated by a nuclear receptor. Mol Cell [Erratum (2010) 37:588] 36:340-347.
43. Ye F, Chen Y, Hoang T, Montgomery RL, Zhao XH, Bu H, Hu T, Taketo MM, van Es JH, Clevers H, Hsieh J, Bassel-Duby R, Olson EN, Lu QR (2009) HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction. Nat Neurosci 12:829-838.
44. Zeis T, Probst A, Steck AJ, Stadelmann C, Brück W, Schaeren-Wiemers N (2009) Molecular changes in white matter adjacent to an active demyelinating lesion in early multiple sclerosis. Brain Pathol 19:459-466.