-
1
-
-
0021079164
-
Immunohistological analysis of T lymphocyte subsets in the central nervous system in chronic progressive multiple sclerosis
-
Booss J, Esiri MM, Tourtellotte WW, Mason DY. Immunohistological analysis of T lymphocyte subsets in the central nervous system in chronic progressive multiple sclerosis. J Neurol Sci (1983) 62:219-32. doi:10.1016/0022-510X(83)90201-0.
-
(1983)
J Neurol Sci
, vol.62
, pp. 219-232
-
-
Booss, J.1
Esiri, M.M.2
Tourtellotte, W.W.3
Mason, D.Y.4
-
2
-
-
0034618094
-
Clonal expansions of CD8(+) T cells dominate the T cell infiltrate in active multiple sclerosis lesions as shown by micromanipulation and single cell polymerase chain reaction
-
Babbe H, Roers A, Waisman A, Lassmann H, Goebels N, Hohlfeld R, et al. Clonal expansions of CD8(+) T cells dominate the T cell infiltrate in active multiple sclerosis lesions as shown by micromanipulation and single cell polymerase chain reaction. J Exp Med (2000) 192:393-404. doi:10.1084/jem.192.3.393.
-
(2000)
J Exp Med
, vol.192
, pp. 393-404
-
-
Babbe, H.1
Roers, A.2
Waisman, A.3
Lassmann, H.4
Goebels, N.5
Hohlfeld, R.6
-
3
-
-
0036191549
-
Oligoclonal expansion of memory CD8+ T cells in cerebrospinal fluid from multiple sclerosis patients
-
Jacobsen M, Cepok S, Quak E, Happel M, Gaber R, Ziegler A, et al. Oligoclonal expansion of memory CD8+ T cells in cerebrospinal fluid from multiple sclerosis patients. Brain (2002) 125:538-50. doi:10.1093/brain/awf059.
-
(2002)
Brain
, vol.125
, pp. 538-550
-
-
Jacobsen, M.1
Cepok, S.2
Quak, E.3
Happel, M.4
Gaber, R.5
Ziegler, A.6
-
4
-
-
35648948324
-
Multiple sclerosis: T-cell receptor expression in distinct brain regions
-
Junker A, Ivanidze J, Malotka J, Eiglmeier I, Lassmann H, Wekerle H, et al. Multiple sclerosis: T-cell receptor expression in distinct brain regions. Brain (2007) 130:2789-99. doi:10.1093/brain/awm214.
-
(2007)
Brain
, vol.130
, pp. 2789-2799
-
-
Junker, A.1
Ivanidze, J.2
Malotka, J.3
Eiglmeier, I.4
Lassmann, H.5
Wekerle, H.6
-
5
-
-
79951960075
-
Neuroantigen-specific CD8+ regulatory T-cell function is deficient during acute exacerbation of multiple sclerosis
-
Baughman EJ, Mendoza JP, Ortega SB, Ayers CL, Greenberg BM, Frohman EM, et al. Neuroantigen-specific CD8+ regulatory T-cell function is deficient during acute exacerbation of multiple sclerosis. J Autoimmun (2011) 36:115-24. doi:10.1016/j.jaut.2010.12.003.
-
(2011)
J Autoimmun
, vol.36
, pp. 115-124
-
-
Baughman, E.J.1
Mendoza, J.P.2
Ortega, S.B.3
Ayers, C.L.4
Greenberg, B.M.5
Frohman, E.M.6
-
6
-
-
2542418993
-
High prevalence of autoreactive neuroantigen-specific CD8+ T cells in multiple sclerosis revealed by novel flow cytometric assay
-
Crawford MP, Yan SX, Ortega SB, Mehta RS, Hewitt RE, Price DA, et al. High prevalence of autoreactive neuroantigen-specific CD8+ T cells in multiple sclerosis revealed by novel flow cytometric assay. Blood (2004) 103:4222-31. doi:10.1182/blood-2003-11-4025.
-
(2004)
Blood
, vol.103
, pp. 4222-4231
-
-
Crawford, M.P.1
Yan, S.X.2
Ortega, S.B.3
Mehta, R.S.4
Hewitt, R.E.5
Price, D.A.6
-
7
-
-
0036195878
-
Glatiramer acetate (Copaxone) therapy induces CD8(+) T cell responses in patients with multiple sclerosis
-
Karandikar NJ, Crawford MP, Yan X, Ratts RB, Brenchley JM, Ambrozak DR, et al. Glatiramer acetate (Copaxone) therapy induces CD8(+) T cell responses in patients with multiple sclerosis. J Clin Invest (2002) 109:641-9. doi:10.1172/JCI200214380.
-
(2002)
J Clin Invest
, vol.109
, pp. 641-649
-
-
Karandikar, N.J.1
Crawford, M.P.2
Yan, X.3
Ratts, R.B.4
Brenchley, J.M.5
Ambrozak, D.R.6
-
8
-
-
33646879037
-
Therapeutic induction of regulatory, cytotoxic CD8+ T cells in multiple sclerosis
-
Tennakoon DK, Mehta RS, Ortega SB, Bhoj V, Racke MK, Karandikar NJ. Therapeutic induction of regulatory, cytotoxic CD8+ T cells in multiple sclerosis. J Immunol (2006) 176:7119-29. doi:10.4049/jimmunol.176.11.7119.
-
(2006)
J Immunol
, vol.176
, pp. 7119-7129
-
-
Tennakoon, D.K.1
Mehta, R.S.2
Ortega, S.B.3
Bhoj, V.4
Racke, M.K.5
Karandikar, N.J.6
-
9
-
-
38549083107
-
HLA-A confers an HLA-DRB1 independent influence on the risk of multiple sclerosis
-
Brynedal B, Duvefelt K, Jonasdottir G, Roos IM, Akesson E, Palmgren J, et al. HLA-A confers an HLA-DRB1 independent influence on the risk of multiple sclerosis. PLoS One (2007) 2:e664. doi:10.1371/journal.pone.0000664.
-
(2007)
PLoS One
, vol.2
-
-
Brynedal, B.1
Duvefelt, K.2
Jonasdottir, G.3
Roos, I.M.4
Akesson, E.5
Palmgren, J.6
-
10
-
-
0033975139
-
Multiple sclerosis: a modifying influence of HLA class I genes in an HLA class II associated autoimmune disease
-
Fogdell-Hahn A, Ligers A, Gronning M, Hillert J, Olerup O. Multiple sclerosis: a modifying influence of HLA class I genes in an HLA class II associated autoimmune disease. Tissue Antigens (2000) 55:140-8. doi:10.1034/j.1399-0039.2000.550205.x.
-
(2000)
Tissue Antigens
, vol.55
, pp. 140-148
-
-
Fogdell-Hahn, A.1
Ligers, A.2
Gronning, M.3
Hillert, J.4
Olerup, O.5
-
11
-
-
10744231677
-
Genes in the HLA class I region may contribute to the HLA class II-associated genetic susceptibility to multiple sclerosis
-
Harbo HF, Lie BA, Sawcer S, Celius EG, Dai KZ, Oturai A, et al. Genes in the HLA class I region may contribute to the HLA class II-associated genetic susceptibility to multiple sclerosis. Tissue Antigens (2004) 63:237-47. doi:10.1111/j.0001-2815.2004.00173.x.
-
(2004)
Tissue Antigens
, vol.63
, pp. 237-247
-
-
Harbo, H.F.1
Lie, B.A.2
Sawcer, S.3
Celius, E.G.4
Dai, K.Z.5
Oturai, A.6
-
12
-
-
55549104692
-
Opposing effects of HLA class I molecules in tuning autoreactive CD8+ T cells in multiple sclerosis
-
Friese MA, Jakobsen KB, Friis L, Etzensperger R, Craner MJ, McMahon RM, et al. Opposing effects of HLA class I molecules in tuning autoreactive CD8+ T cells in multiple sclerosis. Nat Med (2008) 14:1227-35. doi:10.1038/nm.1881.
-
(2008)
Nat Med
, vol.14
, pp. 1227-1235
-
-
Friese, M.A.1
Jakobsen, K.B.2
Friis, L.3
Etzensperger, R.4
Craner, M.J.5
McMahon, R.M.6
-
13
-
-
0035801332
-
A pathogenic role for myelin-specific CD8(+) T cells in a model for multiple sclerosis
-
Huseby ES, Liggitt D, Brabb T, Schnabel B, Ohlen C, Goverman J. A pathogenic role for myelin-specific CD8(+) T cells in a model for multiple sclerosis. J Exp Med (2001) 194:669-76. doi:10.1084/jem.194.5.669.
-
(2001)
J Exp Med
, vol.194
, pp. 669-676
-
-
Huseby, E.S.1
Liggitt, D.2
Brabb, T.3
Schnabel, B.4
Ohlen, C.5
Goverman, J.6
-
14
-
-
77953758560
-
Viral infection triggers central nervous system autoimmunity via activation of CD8+ T cells expressing dual TCRs
-
Ji Q, Perchellet A, Goverman JM. Viral infection triggers central nervous system autoimmunity via activation of CD8+ T cells expressing dual TCRs. Nat Immunol (2010) 11:628-34. doi:10.1038/ni.1888.
-
(2010)
Nat Immunol
, vol.11
, pp. 628-634
-
-
Ji, Q.1
Perchellet, A.2
Goverman, J.M.3
-
15
-
-
0035877190
-
Myelin antigen-specific CD8+ T cells are encephalitogenic and produce severe disease in C57BL/6 mice
-
Sun D, Whitaker JN, Huang Z, Liu D, Coleclough C, Wekerle H, et al. Myelin antigen-specific CD8+ T cells are encephalitogenic and produce severe disease in C57BL/6 mice. J Immunol (2001) 166:7579-87. doi:10.4049/jimmunol.166.12.7579.
-
(2001)
J Immunol
, vol.166
, pp. 7579-7587
-
-
Sun, D.1
Whitaker, J.N.2
Huang, Z.3
Liu, D.4
Coleclough, C.5
Wekerle, H.6
-
16
-
-
12344280009
-
Specificity, magnitude, and kinetics of MOG-specific CD8+ T cell responses during experimental autoimmune encephalomyelitis
-
Ford ML, Evavold BD. Specificity, magnitude, and kinetics of MOG-specific CD8+ T cell responses during experimental autoimmune encephalomyelitis. Eur J Immunol (2005) 35:76-85. doi:10.1002/eji.200425660.
-
(2005)
Eur J Immunol
, vol.35
, pp. 76-85
-
-
Ford, M.L.1
Evavold, B.D.2
-
17
-
-
84897568734
-
Relapsing-remitting central nervous system autoimmunity mediated by GFAP-specific CD8 T cells
-
Sasaki K, Bean A, Shah S, Schutten E, Huseby PG, Peters B, et al. Relapsing-remitting central nervous system autoimmunity mediated by GFAP-specific CD8 T cells. J Immunol (2014) 192:3029-42. doi:10.4049/jimmunol.1302911.
-
(2014)
J Immunol
, vol.192
, pp. 3029-3042
-
-
Sasaki, K.1
Bean, A.2
Shah, S.3
Schutten, E.4
Huseby, P.G.5
Peters, B.6
-
18
-
-
84908140157
-
Blocking initial infiltration of pioneer CD8(+) T-cells into the CNS via inhibition of SHP-2 ameliorates experimental autoimmune encephalomyelitis in mice
-
Luo Q, Sun Y, Gong FY, Liu W, Zheng W, Shen Y, et al. Blocking initial infiltration of pioneer CD8(+) T-cells into the CNS via inhibition of SHP-2 ameliorates experimental autoimmune encephalomyelitis in mice. Br J Pharmacol (2014) 171:1706-21. doi:10.1111/bph.12565.
-
(2014)
Br J Pharmacol
, vol.171
, pp. 1706-1721
-
-
Luo, Q.1
Sun, Y.2
Gong, F.Y.3
Liu, W.4
Zheng, W.5
Shen, Y.6
-
19
-
-
84863116374
-
A transgenic model of central nervous system autoimmunity mediated by CD4+ and CD8+ T and B cells
-
Anderson AC, Chandwaskar R, Lee DH, Sullivan JM, Solomon A, Rodriguez-Manzanet R, et al. A transgenic model of central nervous system autoimmunity mediated by CD4+ and CD8+ T and B cells. J Immunol (2012) 188:2084-92. doi:10.4049/jimmunol.1102186.
-
(2012)
J Immunol
, vol.188
, pp. 2084-2092
-
-
Anderson, A.C.1
Chandwaskar, R.2
Lee, D.H.3
Sullivan, J.M.4
Solomon, A.5
Rodriguez-Manzanet, R.6
-
20
-
-
77952577174
-
A critical role for virus-specific CD8(+) CTLs in protection from Theiler's virus-induced demyelination in disease-susceptible SJL mice
-
Getts MT, Richards MH, Miller SD. A critical role for virus-specific CD8(+) CTLs in protection from Theiler's virus-induced demyelination in disease-susceptible SJL mice. Virology (2010) 402:102-11. doi:10.1016/j.virol.2010.02.031.
-
(2010)
Virology
, vol.402
, pp. 102-111
-
-
Getts, M.T.1
Richards, M.H.2
Miller, S.D.3
-
21
-
-
0036681780
-
Bystander CD8 T cell-mediated demyelination after viral infection of the central nervous system
-
Haring JS, Pewe LL, Perlman S. Bystander CD8 T cell-mediated demyelination after viral infection of the central nervous system. J Immunol (2002) 169:1550-5. doi:10.4049/jimmunol.169.3.1550.
-
(2002)
J Immunol
, vol.169
, pp. 1550-1555
-
-
Haring, J.S.1
Pewe, L.L.2
Perlman, S.3
-
22
-
-
0030060990
-
Adoptively transferred CD8+ T lymphocytes provide protection against TMEV-induced demyelinating disease in BALB/c mice
-
Nicholson SM, Dal Canto MC, Miller SD, Melvold RW. Adoptively transferred CD8+ T lymphocytes provide protection against TMEV-induced demyelinating disease in BALB/c mice. J Immunol (1996) 156:1276-83.
-
(1996)
J Immunol
, vol.156
, pp. 1276-1283
-
-
Nicholson, S.M.1
Dal Canto, M.C.2
Miller, S.D.3
Melvold, R.W.4
-
23
-
-
0034842960
-
Transection of major histocompatibility complex class I-induced neurites by cytotoxic T lymphocytes
-
Medana I, Martinic MA, Wekerle H, Neumann H. Transection of major histocompatibility complex class I-induced neurites by cytotoxic T lymphocytes. Am J Pathol (2001) 159:809-15. doi:10.1016/S0002-9440(10)61755-5.
-
(2001)
Am J Pathol
, vol.159
, pp. 809-815
-
-
Medana, I.1
Martinic, M.A.2
Wekerle, H.3
Neumann, H.4
-
24
-
-
71849115156
-
Cytotoxic CD8+ T cell-neuron interactions: perforin-dependent electrical silencing precedes but is not causally linked to neuronal cell death
-
Meuth SG, Herrmann AM, Simon OJ, Siffrin V, Melzer N, Bittner S, et al. Cytotoxic CD8+ T cell-neuron interactions: perforin-dependent electrical silencing precedes but is not causally linked to neuronal cell death. J Neurosci (2009) 29:15397-409. doi:10.1523/JNEUROSCI.4339-09.2009.
-
(2009)
J Neurosci
, vol.29
, pp. 15397-15409
-
-
Meuth, S.G.1
Herrmann, A.M.2
Simon, O.J.3
Siffrin, V.4
Melzer, N.5
Bittner, S.6
-
25
-
-
84885463512
-
Neuroprotective intervention by interferon-gamma blockade prevents CD8+ T cell-mediated dendrite and synapse loss
-
Kreutzfeldt M, Bergthaler A, Fernandez M, Bruck W, Steinbach K, Vorm M, et al. Neuroprotective intervention by interferon-gamma blockade prevents CD8+ T cell-mediated dendrite and synapse loss. J Exp Med (2013) 210:2087-103. doi:10.1084/jem.20122143.
-
(2013)
J Exp Med
, vol.210
, pp. 2087-2103
-
-
Kreutzfeldt, M.1
Bergthaler, A.2
Fernandez, M.3
Bruck, W.4
Steinbach, K.5
Vorm, M.6
-
26
-
-
84883019402
-
Axons are injured by antigen-specific CD8(+) T cells through a MHC class I- and granzyme B-dependent mechanism
-
Sauer BM, Schmalstieg WF, Howe CL. Axons are injured by antigen-specific CD8(+) T cells through a MHC class I- and granzyme B-dependent mechanism. Neurobiol Dis (2013) 59:194-205. doi:10.1016/j.nbd.2013.07.010.
-
(2013)
Neurobiol Dis
, vol.59
, pp. 194-205
-
-
Sauer, B.M.1
Schmalstieg, W.F.2
Howe, C.L.3
-
27
-
-
30944449259
-
Induction of experimental autoimmune encephalomyelitis in transgenic mice expressing ovalbumin in oligodendrocytes
-
Cao Y, Toben C, Na SY, Stark K, Nitschke L, Peterson A, et al. Induction of experimental autoimmune encephalomyelitis in transgenic mice expressing ovalbumin in oligodendrocytes. Eur J Immunol (2006) 36:207-15. doi:10.1002/eji.200535211.
-
(2006)
Eur J Immunol
, vol.36
, pp. 207-215
-
-
Cao, Y.1
Toben, C.2
Na, S.Y.3
Stark, K.4
Nitschke, L.5
Peterson, A.6
-
28
-
-
71549141283
-
Antigen-specific blockade of lethal CD8 T-cell mediated autoimmunity in a mouse model of multiple sclerosis
-
Na SY, Eujen H, Gobel K, Meuth SG, Martens K, Wiendl H, et al. Antigen-specific blockade of lethal CD8 T-cell mediated autoimmunity in a mouse model of multiple sclerosis. J Immunol (2009) 182:6569-75. doi:10.4049/jimmunol.0804200.
-
(2009)
J Immunol
, vol.182
, pp. 6569-6575
-
-
Na, S.Y.1
Eujen, H.2
Gobel, K.3
Meuth, S.G.4
Martens, K.5
Wiendl, H.6
-
29
-
-
69249092613
-
A Th17-like developmental process leads to CD8(+) Tc17 cells with reduced cytotoxic activity
-
Huber M, Heink S, Grothe H, Guralnik A, Reinhard K, Elflein K, et al. A Th17-like developmental process leads to CD8(+) Tc17 cells with reduced cytotoxic activity. Eur J Immunol (2009) 39:1716-25. doi:10.1002/eji.200939412.
-
(2009)
Eur J Immunol
, vol.39
, pp. 1716-1725
-
-
Huber, M.1
Heink, S.2
Grothe, H.3
Guralnik, A.4
Reinhard, K.5
Elflein, K.6
-
30
-
-
84873825806
-
IL-17A secretion by CD8+ T cells supports Th17-mediated autoimmune encephalomyelitis
-
Huber M, Heink S, Pagenstecher A, Reinhard K, Ritter J, Visekruna A, et al. IL-17A secretion by CD8+ T cells supports Th17-mediated autoimmune encephalomyelitis. J Clin Invest (2013) 123:247-60. doi:10.1172/JCI63681.
-
(2013)
J Clin Invest
, vol.123
, pp. 247-260
-
-
Huber, M.1
Heink, S.2
Pagenstecher, A.3
Reinhard, K.4
Ritter, J.5
Visekruna, A.6
-
31
-
-
84905735685
-
Immune regulation of multiple sclerosis by CD8+ T cells
-
Sinha S, Itani FR, Karandikar NJ. Immune regulation of multiple sclerosis by CD8+ T cells. Immunol Res (2014) 59:254-65. doi:10.1007/s12026-014-8529-9.
-
(2014)
Immunol Res
, vol.59
, pp. 254-265
-
-
Sinha, S.1
Itani, F.R.2
Karandikar, N.J.3
-
32
-
-
85047690427
-
Regulatory functions of CD8+CD28- T cells in an autoimmune disease model
-
Najafian N, Chitnis T, Salama AD, Zhu B, Benou C, Yuan X, et al. Regulatory functions of CD8+CD28- T cells in an autoimmune disease model. J Clin Invest (2003) 112:1037-48. doi:10.1172/JCI17935.
-
(2003)
J Clin Invest
, vol.112
, pp. 1037-1048
-
-
Najafian, N.1
Chitnis, T.2
Salama, A.D.3
Zhu, B.4
Benou, C.5
Yuan, X.6
-
33
-
-
17444416484
-
EAE in beta-2 microglobulin-deficient mice: axonal damage is not dependent on MHC-I restricted immune responses
-
Linker RA, Rott E, Hofstetter HH, Hanke T, Toyka KV, Gold R. EAE in beta-2 microglobulin-deficient mice: axonal damage is not dependent on MHC-I restricted immune responses. Neurobiol Dis (2005) 19:218-28. doi:10.1016/j.nbd.2004.12.017.
-
(2005)
Neurobiol Dis
, vol.19
, pp. 218-228
-
-
Linker, R.A.1
Rott, E.2
Hofstetter, H.H.3
Hanke, T.4
Toyka, K.V.5
Gold, R.6
-
34
-
-
84879634299
-
The disease-ameliorating function of autoregulatory CD8 T cells is mediated by targeting of encephalitogenic CD4 T cells in experimental autoimmune encephalomyelitis
-
Ortega SB, Kashi VP, Tyler AF, Cunnusamy K, Mendoza JP, Karandikar NJ. The disease-ameliorating function of autoregulatory CD8 T cells is mediated by targeting of encephalitogenic CD4 T cells in experimental autoimmune encephalomyelitis. J Immunol (2013) 191:117-26. doi:10.4049/jimmunol.1300452.
-
(2013)
J Immunol
, vol.191
, pp. 117-126
-
-
Ortega, S.B.1
Kashi, V.P.2
Tyler, A.F.3
Cunnusamy, K.4
Mendoza, J.P.5
Karandikar, N.J.6
-
35
-
-
35848945932
-
CD8+ T cells in inflammatory demyelinating disease
-
Weiss HA, Millward JM, Owens T. CD8+ T cells in inflammatory demyelinating disease. J Neuroimmunol (2007) 191:79-85. doi:10.1016/j.jneuroim.2007.09.011.
-
(2007)
J Neuroimmunol
, vol.191
, pp. 79-85
-
-
Weiss, H.A.1
Millward, J.M.2
Owens, T.3
-
36
-
-
77953289016
-
Immune regulatory CNS-reactive CD8+T cells in experimental autoimmune encephalomyelitis
-
York NR, Mendoza JP, Ortega SB, Benagh A, Tyler AF, Firan M, et al. Immune regulatory CNS-reactive CD8+T cells in experimental autoimmune encephalomyelitis. J Autoimmun (2010) 35:33-44. doi:10.1016/j.jaut.2010.01.003.
-
(2010)
J Autoimmun
, vol.35
, pp. 33-44
-
-
York, N.R.1
Mendoza, J.P.2
Ortega, S.B.3
Benagh, A.4
Tyler, A.F.5
Firan, M.6
-
37
-
-
84952918668
-
Autoregulatory CD8 T cells depend on cognate antigen recognition and CD4/CD* myelin determinants
-
Ortega SB, Kashi VP, Cunnusamy K, Franco J, Karandikar NJ. Autoregulatory CD8 T cells depend on cognate antigen recognition and CD4/CD* myelin determinants. Neurol Neuroimmunol Neuroinflamm (2015) 2:e170. doi:10.1212/NXI.0000000000000170.
-
(2015)
Neurol Neuroimmunol Neuroinflamm
, vol.2
-
-
Ortega, S.B.1
Kashi, V.P.2
Cunnusamy, K.3
Franco, J.4
Karandikar, N.J.5
-
38
-
-
0022995760
-
Defective suppressor cell function mediated by T8+ cell lines from patients with progressive multiple sclerosis
-
Antel J, Bania M, Noronha A, Neely S. Defective suppressor cell function mediated by T8+ cell lines from patients with progressive multiple sclerosis. J Immunol (1986) 137:3436-9.
-
(1986)
J Immunol
, vol.137
, pp. 3436-3439
-
-
Antel, J.1
Bania, M.2
Noronha, A.3
Neely, S.4
-
39
-
-
0022446678
-
Suppressor and cytolytic cell function in multiple sclerosi. Effects of cyclosporine A and interleukin 2
-
Bania MB, Antel JP, Reder AT, Nicholas MK, Arnason BG. Suppressor and cytolytic cell function in multiple sclerosis. Effects of cyclosporine A and interleukin 2. J Clin Invest (1986) 78:582-6. doi:10.1172/JCI112612.
-
(1986)
J Clin Invest
, vol.78
, pp. 582-586
-
-
Bania, M.B.1
Antel, J.P.2
Reder, A.T.3
Nicholas, M.K.4
Arnason, B.G.5
-
40
-
-
84876337179
-
Modulation of immune function occurs within hours of therapy initiation for multiple sclerosis
-
Ayers CL, Mendoza JP, Sinha S, Cunnusamy K, Greenberg BM, Frohman EM, et al. Modulation of immune function occurs within hours of therapy initiation for multiple sclerosis. Clin Immunol (2013) 147:105-19. doi:10.1016/j.clim.2013.02.015.
-
(2013)
Clin Immunol
, vol.147
, pp. 105-119
-
-
Ayers, C.L.1
Mendoza, J.P.2
Sinha, S.3
Cunnusamy, K.4
Greenberg, B.M.5
Frohman, E.M.6
-
41
-
-
84902145624
-
HLA-E restricted CD8+ T cell subsets are phenotypically altered in multiple sclerosis patients
-
Pannemans K, Broux B, Goris A, Dubois B, Broekmans T, Van Wijmeersch B, et al. HLA-E restricted CD8+ T cell subsets are phenotypically altered in multiple sclerosis patients. Mult Scler (2013) 20:790-801. doi:10.1177/1352458513509703.
-
(2013)
Mult Scler
, vol.20
, pp. 790-801
-
-
Pannemans, K.1
Broux, B.2
Goris, A.3
Dubois, B.4
Broekmans, T.5
Van Wijmeersch, B.6
-
42
-
-
36048963838
-
LAG-3 regulates CD8+ T cell accumulation and effector function in murine self- and tumor-tolerance systems
-
Grosso JF, Kelleher CC, Harris TJ, Maris CH, Hipkiss EL, De Marzo A, et al. LAG-3 regulates CD8+ T cell accumulation and effector function in murine self- and tumor-tolerance systems. J Clin Invest (2007) 117:3383-92. doi:10.1172/JCI31184.
-
(2007)
J Clin Invest
, vol.117
, pp. 3383-3392
-
-
Grosso, J.F.1
Kelleher, C.C.2
Harris, T.J.3
Maris, C.H.4
Hipkiss, E.L.5
De Marzo, A.6
-
43
-
-
57449097190
-
CD8+ regulatory T cells are responsible for GAD-IgG gene-transferred tolerance induction in NOD mice
-
Wang R, Han G, Song L, Wang J, Chen G, Xu R, et al. CD8+ regulatory T cells are responsible for GAD-IgG gene-transferred tolerance induction in NOD mice. Immunology (2009) 126:123-31. doi:10.1111/j.1365-2567.2008.02884.x.
-
(2009)
Immunology
, vol.126
, pp. 123-131
-
-
Wang, R.1
Han, G.2
Song, L.3
Wang, J.4
Chen, G.5
Xu, R.6
-
44
-
-
79251534981
-
CD8+CD122+ regulatory T cells (Tregs) and CD4+ Tregs cooperatively prevent and cure CD4+ cell-induced colitis
-
Endharti AT, Okuno Y, Shi Z, Misawa N, Toyokuni S, Ito M, et al. CD8+CD122+ regulatory T cells (Tregs) and CD4+ Tregs cooperatively prevent and cure CD4+ cell-induced colitis. J Immunol (2011) 186:41-52. doi:10.4049/jimmunol.1000800.
-
(2011)
J Immunol
, vol.186
, pp. 41-52
-
-
Endharti, A.T.1
Okuno, Y.2
Shi, Z.3
Misawa, N.4
Toyokuni, S.5
Ito, M.6
-
45
-
-
77956895738
-
Inhibition of follicular T-helper cells by CD8(+) regulatory T cells is essential for self tolerance
-
Kim HJ, Verbinnen B, Tang X, Lu L, Cantor H. Inhibition of follicular T-helper cells by CD8(+) regulatory T cells is essential for self tolerance. Nature (2010) 467:328-32. doi:10.1038/nature09370.
-
(2010)
Nature
, vol.467
, pp. 328-332
-
-
Kim, H.J.1
Verbinnen, B.2
Tang, X.3
Lu, L.4
Cantor, H.5
-
46
-
-
36049042893
-
CD8+CD122+ T cells, a newly identified regulatory T subset, negatively regulate Graves' hyperthyroidism in a murine model
-
Saitoh O, Abiru N, Nakahara M, Nagayama Y. CD8+CD122+ T cells, a newly identified regulatory T subset, negatively regulate Graves' hyperthyroidism in a murine model. Endocrinology (2007) 148:6040-6. doi:10.1210/en.2007-0300.
-
(2007)
Endocrinology
, vol.148
, pp. 6040-6046
-
-
Saitoh, O.1
Abiru, N.2
Nakahara, M.3
Nagayama, Y.4
-
47
-
-
77955498050
-
Mechanism and localization of CD8 regulatory T cells in a heart transplant model of tolerance
-
Li XL, Menoret S, Bezie S, Caron L, Chabannes D, Hill M, et al. Mechanism and localization of CD8 regulatory T cells in a heart transplant model of tolerance. J Immunol (2010) 185:823-33. doi:10.4049/jimmunol.1000120.
-
(2010)
J Immunol
, vol.185
, pp. 823-833
-
-
Li, X.L.1
Menoret, S.2
Bezie, S.3
Caron, L.4
Chabannes, D.5
Hill, M.6
-
48
-
-
57649104328
-
Inhibitory CD8+ T cells in autoimmune disease
-
Suzuki M, Konya C, Goronzy JJ, Weyand CM. Inhibitory CD8+ T cells in autoimmune disease. Hum Immunol (2008) 69:781-9. doi:10.1016/j.humimm.2008.08.283.
-
(2008)
Hum Immunol
, vol.69
, pp. 781-789
-
-
Suzuki, M.1
Konya, C.2
Goronzy, J.J.3
Weyand, C.M.4
-
49
-
-
80053055061
-
Development of memory-like autoregulatory CD8+ T cells is CD4+ T cell dependent
-
Shameli A, Clemente-Casares X, Wang J, Santamaria P. Development of memory-like autoregulatory CD8+ T cells is CD4+ T cell dependent. J Immunol (2011) 187:2859-66. doi:10.4049/jimmunol.1101117.
-
(2011)
J Immunol
, vol.187
, pp. 2859-2866
-
-
Shameli, A.1
Clemente-Casares, X.2
Wang, J.3
Santamaria, P.4
-
50
-
-
77951882989
-
Reversal of autoimmunity by boosting memory-like autoregulatory T cells
-
Tsai S, Shameli A, Yamanouchi J, Clemente-Casares X, Wang J, Serra P, et al. Reversal of autoimmunity by boosting memory-like autoregulatory T cells. Immunity (2010) 32:568-80. doi:10.1016/j.immuni.2010.03.015.
-
(2010)
Immunity
, vol.32
, pp. 568-580
-
-
Tsai, S.1
Shameli, A.2
Yamanouchi, J.3
Clemente-Casares, X.4
Wang, J.5
Serra, P.6
-
51
-
-
40449120318
-
Essential role of CD8+CD122+ regulatory T cells in the recovery from experimental autoimmune encephalomyelitis
-
Lee YH, Ishida Y, Rifa'i M, Shi Z, Isobe K, Suzuki H. Essential role of CD8+CD122+ regulatory T cells in the recovery from experimental autoimmune encephalomyelitis. J Immunol (2008) 180:825-32. doi:10.4049/jimmunol.180.2.825.
-
(2008)
J Immunol
, vol.180
, pp. 825-832
-
-
Lee, Y.H.1
Ishida, Y.2
Rifa'i, M.3
Shi, Z.4
Isobe, K.5
Suzuki, H.6
-
52
-
-
84861193712
-
Two discreet subsets of CD8 T cells modulate PLP(91-110) induced experimental autoimmune encephalomyelitis in HLA-DR3 transgenic mice
-
Mangalam AK, Luckey D, Giri S, Smart M, Pease LR, Rodriguez M, et al. Two discreet subsets of CD8 T cells modulate PLP(91-110) induced experimental autoimmune encephalomyelitis in HLA-DR3 transgenic mice. J Autoimmun (2012) 38:344-53. doi:10.1016/j.jaut.2012.02.004.
-
(2012)
J Autoimmun
, vol.38
, pp. 344-353
-
-
Mangalam, A.K.1
Luckey, D.2
Giri, S.3
Smart, M.4
Pease, L.R.5
Rodriguez, M.6
-
53
-
-
84916879284
-
IL-15-dependent CD8+ CD122+ T cells ameliorate experimental autoimmune encephalomyelitis by modulating IL-17 production by CD4+ T cells
-
Yu P, Bamford RN, Waldmann TA. IL-15-dependent CD8+ CD122+ T cells ameliorate experimental autoimmune encephalomyelitis by modulating IL-17 production by CD4+ T cells. Eur J Immunol (2014) 44:3330-41. doi:10.1002/eji.201444675.
-
(2014)
Eur J Immunol
, vol.44
, pp. 3330-3341
-
-
Yu, P.1
Bamford, R.N.2
Waldmann, T.A.3
-
54
-
-
0035173022
-
Ocular immune privilege promoted by the presentation of peptide on tolerogenic B cells in the spleen. II. Evidence for presentation by Qa-1
-
D'Orazio TJ, Mayhew E, Niederkorn JY. Ocular immune privilege promoted by the presentation of peptide on tolerogenic B cells in the spleen. II. Evidence for presentation by Qa-1. J Immunol (2001) 166:26-32.
-
(2001)
J Immunol
, vol.166
, pp. 26-32
-
-
D'Orazio, T.J.1
Mayhew, E.2
Niederkorn, J.Y.3
-
55
-
-
0344851544
-
Splenic B cells act as antigen presenting cells for the induction of anterior chamber-associated immune deviation
-
Skelsey ME, Mayhew E, Niederkorn JY. Splenic B cells act as antigen presenting cells for the induction of anterior chamber-associated immune deviation. Invest Ophthalmol Vis Sci (2003) 44:5242-51. doi:10.1167/iovs.03-0768.
-
(2003)
Invest Ophthalmol Vis Sci
, vol.44
, pp. 5242-5251
-
-
Skelsey, M.E.1
Mayhew, E.2
Niederkorn, J.Y.3
-
56
-
-
41149134995
-
Implication for the CD94/NKG2A-Qa-1 system in the generation and function of ocular-induced splenic CD8+ regulatory T cells
-
Chattopadhyay S, O'Rourke J, Cone RE. Implication for the CD94/NKG2A-Qa-1 system in the generation and function of ocular-induced splenic CD8+ regulatory T cells. Int Immunol (2008) 20:509-16. doi:10.1093/intimm/dxn008.
-
(2008)
Int Immunol
, vol.20
, pp. 509-516
-
-
Chattopadhyay, S.1
O'Rourke, J.2
Cone, R.E.3
-
57
-
-
33645964981
-
CD8+ T regulatory cells use a novel genetic program that includes CD103 to suppress Th1 immunity in eye-derived tolerance
-
Keino H, Masli S, Sasaki S, Streilein JW, Stein-Streilein J. CD8+ T regulatory cells use a novel genetic program that includes CD103 to suppress Th1 immunity in eye-derived tolerance. Invest Ophthalmol Vis Sci (2006) 47:1533-42. doi:10.1167/iovs.04-1454.
-
(2006)
Invest Ophthalmol Vis Sci
, vol.47
, pp. 1533-1542
-
-
Keino, H.1
Masli, S.2
Sasaki, S.3
Streilein, J.W.4
Stein-Streilein, J.5
-
58
-
-
34250793908
-
Increased expression of Foxp3 in splenic CD8+ T cells from mice with anterior chamber-associated immune deviation
-
Jiang L, Yang P, He H, Li B, Lin X, Hou S, et al. Increased expression of Foxp3 in splenic CD8+ T cells from mice with anterior chamber-associated immune deviation. Mol Vis (2007) 13:968-74.
-
(2007)
Mol Vis
, vol.13
, pp. 968-974
-
-
Jiang, L.1
Yang, P.2
He, H.3
Li, B.4
Lin, X.5
Hou, S.6
-
59
-
-
54049102440
-
Upregulation of CD94 on CD8+ T cells in anterior chamber-associated immune deviation
-
He H, Yang P, Jiang L, Zhang J, Zhao C, Chen L, et al. Upregulation of CD94 on CD8+ T cells in anterior chamber-associated immune deviation. BMC Immunol (2008) 9:53. doi:10.1186/1471-2172-9-53.
-
(2008)
BMC Immunol
, vol.9
, pp. 53
-
-
He, H.1
Yang, P.2
Jiang, L.3
Zhang, J.4
Zhao, C.5
Chen, L.6
-
60
-
-
56949106507
-
Splenic CD8+ T cells secrete TGF-beta1 to exert suppression in mice with anterior chamber-associated immune deviation
-
Jiang L, He H, Yang P, Lin X, Zhou H, Huang X, et al. Splenic CD8+ T cells secrete TGF-beta1 to exert suppression in mice with anterior chamber-associated immune deviation. Graefes Arch Clin Exp Ophthalmol (2009) 247:87-92. doi:10.1007/s00417-008-0947-8.
-
(2009)
Graefes Arch Clin Exp Ophthalmol
, vol.247
, pp. 87-92
-
-
Jiang, L.1
He, H.2
Yang, P.3
Lin, X.4
Zhou, H.5
Huang, X.6
-
61
-
-
84888867352
-
In vitro-induced cell-mediated immune deviation to encephalitogenic antigens
-
Farooq SM, Ashour HM. In vitro-induced cell-mediated immune deviation to encephalitogenic antigens. Brain Behav Immun (2014) 35:64-9. doi:10.1016/j.bbi.2013.09.016.
-
(2014)
Brain Behav Immun
, vol.35
, pp. 64-69
-
-
Farooq, S.M.1
Ashour, H.M.2
-
62
-
-
84908609376
-
The in vivo and in vitro induction of anterior chamber associated immune deviation to myelin antigens in C57BL/6 mice
-
Farooq SM, Elkhatib WF, Ashour HM. The in vivo and in vitro induction of anterior chamber associated immune deviation to myelin antigens in C57BL/6 mice. Brain Behav Immun (2014) 42:118-22. doi:10.1016/j.bbi.2014.06.010.
-
(2014)
Brain Behav Immun
, vol.42
, pp. 118-122
-
-
Farooq, S.M.1
Elkhatib, W.F.2
Ashour, H.M.3
-
63
-
-
0035932949
-
CD8+ T cells control the TH phenotype of MBP-reactive CD4+ T cells in EAE mice
-
Jiang H, Braunstein NS, Yu B, Winchester R, Chess L. CD8+ T cells control the TH phenotype of MBP-reactive CD4+ T cells in EAE mice. Proc Natl Acad Sci U S A (2001) 98:6301-6. doi:10.1073/pnas.101123098.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 6301-6306
-
-
Jiang, H.1
Braunstein, N.S.2
Yu, B.3
Winchester, R.4
Chess, L.5
-
64
-
-
84879274140
-
CD8 T cells are required for glatiramer acetate therapy in autoimmune demyelinating disease
-
Tyler AF, Mendoza JP, Firan M, Karandikar NJ. CD8 T cells are required for glatiramer acetate therapy in autoimmune demyelinating disease. PLoS One (2013) 8:e66772. doi:10.1371/journal.pone.0066772.
-
(2013)
PLoS One
, vol.8
-
-
Tyler, A.F.1
Mendoza, J.P.2
Firan, M.3
Karandikar, N.J.4
-
65
-
-
84937826002
-
Neuroantigen-specific autoregulatory CD8+ T cells inhibit autoimmune demyelination through modulation of dendritic cell function
-
Kashi VP, Ortega SB, Karandikar NJ. Neuroantigen-specific autoregulatory CD8+ T cells inhibit autoimmune demyelination through modulation of dendritic cell function. PLoS One (2014) 9:e105763. doi:10.1371/journal.pone.0105763.
-
(2014)
PLoS One
, vol.9
-
-
Kashi, V.P.1
Ortega, S.B.2
Karandikar, N.J.3
-
66
-
-
79953222926
-
Highly activated cytotoxic CD8 T cells express protective IL-10 at the peak of coronavirus-induced encephalitis
-
Trandem K, Zhao J, Fleming E, Perlman S. Highly activated cytotoxic CD8 T cells express protective IL-10 at the peak of coronavirus-induced encephalitis. J Immunol (2011) 186:3642-52. doi:10.4049/jimmunol.1003292.
-
(2011)
J Immunol
, vol.186
, pp. 3642-3652
-
-
Trandem, K.1
Zhao, J.2
Fleming, E.3
Perlman, S.4
-
67
-
-
33751562995
-
Regulation of immunity by a novel population of Qa-1-restricted CD8alphaalpha+TCRalphabeta+ T cells
-
Tang X, Maricic I, Purohit N, Bakamjian B, Reed-Loisel LM, Beeston T, et al. Regulation of immunity by a novel population of Qa-1-restricted CD8alphaalpha+TCRalphabeta+ T cells. J Immunol (2006) 177:7645-55. doi:10.4049/jimmunol.177.11.7645.
-
(2006)
J Immunol
, vol.177
, pp. 7645-7655
-
-
Tang, X.1
Maricic, I.2
Purohit, N.3
Bakamjian, B.4
Reed-Loisel, L.M.5
Beeston, T.6
-
68
-
-
84897931965
-
Disease exacerbation of multiple sclerosis is characterized by loss of terminally differentiated autoregulatory CD8+ T cells
-
Cunnusamy K, Baughman EJ, Franco J, Ortega SB, Sinha S, Chaudhary P, et al. Disease exacerbation of multiple sclerosis is characterized by loss of terminally differentiated autoregulatory CD8+ T cells. Clin Immunol (2014) 152:115-26. doi:10.1016/j.clim.2014.03.005.
-
(2014)
Clin Immunol
, vol.152
, pp. 115-126
-
-
Cunnusamy, K.1
Baughman, E.J.2
Franco, J.3
Ortega, S.B.4
Sinha, S.5
Chaudhary, P.6
-
69
-
-
34547699396
-
Type II monocytes modulate T cell-mediated central nervous system autoimmune disease
-
Weber MS, Prod'homme T, Youssef S, Dunn SE, Rundle CD, Lee L, et al. Type II monocytes modulate T cell-mediated central nervous system autoimmune disease. Nat Med (2007) 13:935-43. doi:10.1038/nm1620.
-
(2007)
Nat Med
, vol.13
, pp. 935-943
-
-
Weber, M.S.1
Prod'homme, T.2
Youssef, S.3
Dunn, S.E.4
Rundle, C.D.5
Lee, L.6
-
70
-
-
2442698974
-
Type 2 monocyte and microglia differentiation mediated by glatiramer acetate therapy in patients with multiple sclerosis
-
Kim HJ, Ifergan I, Antel JP, Seguin R, Duddy M, Lapierre Y, et al. Type 2 monocyte and microglia differentiation mediated by glatiramer acetate therapy in patients with multiple sclerosis. J Immunol (2004) 172:7144-53. doi:10.4049/jimmunol.172.11.7144.
-
(2004)
J Immunol
, vol.172
, pp. 7144-7153
-
-
Kim, H.J.1
Ifergan, I.2
Antel, J.P.3
Seguin, R.4
Duddy, M.5
Lapierre, Y.6
-
71
-
-
2942594278
-
Multiple sclerosis: glatiramer acetate inhibits monocyte reactivity in vitro and in vivo
-
Weber MS, Starck M, Wagenpfeil S, Meinl E, Hohlfeld R, Farina C. Multiple sclerosis: glatiramer acetate inhibits monocyte reactivity in vitro and in vivo. Brain (2004) 127:1370-8. doi:10.1093/brain/awh163.
-
(2004)
Brain
, vol.127
, pp. 1370-1378
-
-
Weber, M.S.1
Starck, M.2
Wagenpfeil, S.3
Meinl, E.4
Hohlfeld, R.5
Farina, C.6
-
72
-
-
0023597814
-
A monoclonal antibody against a myelin oligodendrocyte glycoprotein induces relapses and demyelination in central nervous system autoimmune disease
-
Schluesener HJ, Sobel RA, Linington C, Weiner HL. A monoclonal antibody against a myelin oligodendrocyte glycoprotein induces relapses and demyelination in central nervous system autoimmune disease. J Immunol (1987) 139:4016-21.
-
(1987)
J Immunol
, vol.139
, pp. 4016-4021
-
-
Schluesener, H.J.1
Sobel, R.A.2
Linington, C.3
Weiner, H.L.4
-
73
-
-
0036312179
-
Critical role of antigen-specific antibody in experimental autoimmune encephalomyelitis induced by recombinant myelin oligodendrocyte glycoprotein
-
Lyons JA, Ramsbottom MJ, Cross AH. Critical role of antigen-specific antibody in experimental autoimmune encephalomyelitis induced by recombinant myelin oligodendrocyte glycoprotein. Eur J Immunol (2002) 32:1905-13. doi:10.1002/1521-4141(200207)32:7<1905::AID-IMMU1905>3.0.CO;2-L.
-
(2002)
Eur J Immunol
, vol.32
, pp. 1905-1913
-
-
Lyons, J.A.1
Ramsbottom, M.J.2
Cross, A.H.3
-
74
-
-
0036318944
-
A comparative analysis of B cell-mediated myelin oligodendrocyte glycoprotein-experimental autoimmune encephalomyelitis pathogenesis in B cell-deficient mice reveals an effect on demyelination
-
Svensson L, Abdul-Majid KB, Bauer J, Lassmann H, Harris RA, Holmdahl R. A comparative analysis of B cell-mediated myelin oligodendrocyte glycoprotein-experimental autoimmune encephalomyelitis pathogenesis in B cell-deficient mice reveals an effect on demyelination. Eur J Immunol (2002) 32:1939-46. doi:10.1002/1521-4141(200207)32:7<1939::AID-IMMU1939>3.0.CO;2-S.
-
(2002)
Eur J Immunol
, vol.32
, pp. 1939-1946
-
-
Svensson, L.1
Abdul-Majid, K.B.2
Bauer, J.3
Lassmann, H.4
Harris, R.A.5
Holmdahl, R.6
-
75
-
-
25444508969
-
Pathogenic myelin oligodendrocyte glycoprotein antibodies recognize glycosylated epitopes and perturb oligodendrocyte physiology
-
Marta CB, Oliver AR, Sweet RA, Pfeiffer SE, Ruddle NH. Pathogenic myelin oligodendrocyte glycoprotein antibodies recognize glycosylated epitopes and perturb oligodendrocyte physiology. Proc Natl Acad Sci USA (2005) 102:13992-7. doi:10.1073/pnas.0504979102.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 13992-13997
-
-
Marta, C.B.1
Oliver, A.R.2
Sweet, R.A.3
Pfeiffer, S.E.4
Ruddle, N.H.5
-
76
-
-
54949141219
-
Regulatory B cells inhibit EAE initiation in mice while other B cells promote disease progression
-
Matsushita T, Yanaba K, Bouaziz JD, Fujimoto M, Tedder TF. Regulatory B cells inhibit EAE initiation in mice while other B cells promote disease progression. J Clin Invest (2008) 118:3420-30. doi:10.1172/JCI36030.
-
(2008)
J Clin Invest
, vol.118
, pp. 3420-3430
-
-
Matsushita, T.1
Yanaba, K.2
Bouaziz, J.D.3
Fujimoto, M.4
Tedder, T.F.5
-
77
-
-
77956360533
-
B-cell activation influences T-cell polarization and outcome of anti-CD20 B-cell depletion in central nervous system autoimmunity
-
Weber MS, Prod'homme T, Patarroyo JC, Molnarfi N, Karnezis T, Lehmann-Horn K, et al. B-cell activation influences T-cell polarization and outcome of anti-CD20 B-cell depletion in central nervous system autoimmunity. Ann Neurol (2010) 68:369-83. doi:10.1002/ana.22081.
-
(2010)
Ann Neurol
, vol.68
, pp. 369-383
-
-
Weber, M.S.1
Prod'homme, T.2
Patarroyo, J.C.3
Molnarfi, N.4
Karnezis, T.5
Lehmann-Horn, K.6
-
78
-
-
78650172728
-
The role of antibodies in multiple sclerosis
-
Weber MS, Hemmer B, Cepok S. The role of antibodies in multiple sclerosis. Biochim Biophys Acta (2011) 1812:239-45. doi:10.1016/j.bbadis.2010.06.009.
-
(2011)
Biochim Biophys Acta
, vol.1812
, pp. 239-245
-
-
Weber, M.S.1
Hemmer, B.2
Cepok, S.3
-
79
-
-
79952832197
-
The immunopathophysiology of multiple sclerosis
-
Wu GF, Alvarez E. The immunopathophysiology of multiple sclerosis. Neurol Clin (2011) 29:257-78. doi:10.1016/j.ncl.2010.12.009.
-
(2011)
Neurol Clin
, vol.29
, pp. 257-278
-
-
Wu, G.F.1
Alvarez, E.2
-
80
-
-
84863803849
-
B cell depletion therapy ameliorates autoimmune disease through ablation of IL-6-producing B cells
-
Barr TA, Shen P, Brown S, Lampropoulou V, Roch T, Lawrie S, et al. B cell depletion therapy ameliorates autoimmune disease through ablation of IL-6-producing B cells. J Exp Med (2012) 209:1001-10. doi:10.1084/jem.20111675.
-
(2012)
J Exp Med
, vol.209
, pp. 1001-1010
-
-
Barr, T.A.1
Shen, P.2
Brown, S.3
Lampropoulou, V.4
Roch, T.5
Lawrie, S.6
-
81
-
-
84868525833
-
B cells and antibodies in multiple sclerosis pathogenesis and therapy
-
Krumbholz M, Derfuss T, Hohlfeld R, Meinl E. B cells and antibodies in multiple sclerosis pathogenesis and therapy. Nat Rev Neurol (2012) 8:613-23. doi:10.1038/nrneurol.2012.203.
-
(2012)
Nat Rev Neurol
, vol.8
, pp. 613-623
-
-
Krumbholz, M.1
Derfuss, T.2
Hohlfeld, R.3
Meinl, E.4
-
82
-
-
84893418455
-
B cells promote induction of experimental autoimmune encephalomyelitis by facilitating reactivation of T cells in the central nervous system
-
Pierson ER, Stromnes IM, Goverman JM. B cells promote induction of experimental autoimmune encephalomyelitis by facilitating reactivation of T cells in the central nervous system. J Immunol (2014) 192:929-39. doi:10.4049/jimmunol.1302171.
-
(2014)
J Immunol
, vol.192
, pp. 929-939
-
-
Pierson, E.R.1
Stromnes, I.M.2
Goverman, J.M.3
-
83
-
-
0030456897
-
Experimental autoimmune encephalomyelitis induction in genetically B cell-deficient mice
-
Wolf SD, Dittel BN, Hardardottir F, Janeway CA Jr. Experimental autoimmune encephalomyelitis induction in genetically B cell-deficient mice. J Exp Med (1996) 184:2271-8. doi:10.1084/jem.184.6.2271.
-
(1996)
J Exp Med
, vol.184
, pp. 2271-2278
-
-
Wolf, S.D.1
Dittel, B.N.2
Hardardottir, F.3
Janeway, C.A.4
-
84
-
-
0032729174
-
B cells are critical to induction of experimental allergic encephalomyelitis by protein but not by a short encephalitogenic peptide
-
Lyons JA, San M, Happ MP, Cross AH. B cells are critical to induction of experimental allergic encephalomyelitis by protein but not by a short encephalitogenic peptide. Eur J Immunol (1999) 29:3432-9. doi:10.1002/(SICI)1521-4141(199911)29:11<3432::AID-IMMU3432>3.0.CO;2-2.
-
(1999)
Eur J Immunol
, vol.29
, pp. 3432-3439
-
-
Lyons, J.A.1
San, M.2
Happ, M.P.3
Cross, A.H.4
-
85
-
-
0036795531
-
B cells regulate autoimmunity by provision of IL-10
-
Fillatreau S, Sweenie CH, McGeachy MJ, Gray D, Anderton SM. B cells regulate autoimmunity by provision of IL-10. Nat Immunol (2002) 3:944-50. doi:10.1038/ni833.
-
(2002)
Nat Immunol
, vol.3
, pp. 944-950
-
-
Fillatreau, S.1
Sweenie, C.H.2
McGeachy, M.J.3
Gray, D.4
Anderton, S.M.5
-
86
-
-
42649124913
-
Not always the bad guys: B cells as regulators of autoimmune pathology
-
Fillatreau S, Gray D, Anderton SM. Not always the bad guys: B cells as regulators of autoimmune pathology. Nat Rev Immunol (2008) 8:391-7. doi:10.1038/nri2315.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 391-397
-
-
Fillatreau, S.1
Gray, D.2
Anderton, S.M.3
-
87
-
-
77956895769
-
Regulatory B cells (B10 cells) and regulatory T cells have independent roles in controlling experimental autoimmune encephalomyelitis initiation and late-phase immunopathogenesis
-
Matsushita T, Horikawa M, Iwata Y, Tedder TF. Regulatory B cells (B10 cells) and regulatory T cells have independent roles in controlling experimental autoimmune encephalomyelitis initiation and late-phase immunopathogenesis. J Immunol (2010) 185:2240-52. doi:10.4049/jimmunol.1001307.
-
(2010)
J Immunol
, vol.185
, pp. 2240-2252
-
-
Matsushita, T.1
Horikawa, M.2
Iwata, Y.3
Tedder, T.F.4
-
88
-
-
78650955431
-
Glatiramer acetate for treatment of MS: regulatory B cells join the cast of players
-
Van Kaer L. Glatiramer acetate for treatment of MS: regulatory B cells join the cast of players. Exp Neurol (2011) 227:19-23. doi:10.1016/j.expneurol.2010.10.009.
-
(2011)
Exp Neurol
, vol.227
, pp. 19-23
-
-
Van Kaer, L.1
-
89
-
-
78650996077
-
A case for regulatory B cells in controlling the severity of autoimmune-mediated inflammation in experimental autoimmune encephalomyelitis and multiple sclerosis
-
Ray A, Mann MK, Basu S, Dittel BN. A case for regulatory B cells in controlling the severity of autoimmune-mediated inflammation in experimental autoimmune encephalomyelitis and multiple sclerosis. J Neuroimmunol (2011) 230:1-9. doi:10.1016/j.jneuroim.2010.10.037.
-
(2011)
J Neuroimmunol
, vol.230
, pp. 1-9
-
-
Ray, A.1
Mann, M.K.2
Basu, S.3
Dittel, B.N.4
-
90
-
-
84859385739
-
Immune regulatory function of B cells
-
Mauri C, Bosma A. Immune regulatory function of B cells. Annu Rev Immunol (2012) 30:221-41. doi:10.1146/annurev-immunol-020711-074934.
-
(2012)
Annu Rev Immunol
, vol.30
, pp. 221-241
-
-
Mauri, C.1
Bosma, A.2
-
91
-
-
84868619716
-
Regulatory B cells control T-cell autoimmunity through IL-21-dependent cognate interactions
-
Yoshizaki A, Miyagaki T, DiLillo DJ, Matsushita T, Horikawa M, Kountikov EI, et al. Regulatory B cells control T-cell autoimmunity through IL-21-dependent cognate interactions. Nature (2012) 491:264-8. doi:10.1038/nature11501.
-
(2012)
Nature
, vol.491
, pp. 264-268
-
-
Yoshizaki, A.1
Miyagaki, T.2
DiLillo, D.J.3
Matsushita, T.4
Horikawa, M.5
Kountikov, E.I.6
-
92
-
-
84873601139
-
IL-10-producing regulatory B cells (B10 cells) in autoimmune disease
-
Kalampokis I, Yoshizaki A, Tedder TF. IL-10-producing regulatory B cells (B10 cells) in autoimmune disease. Arthritis Res Ther (2013) 15(Suppl 1):S1. doi:10.1186/ar3907.
-
(2013)
Arthritis Res Ther
, vol.15
, pp. S1
-
-
Kalampokis, I.1
Yoshizaki, A.2
Tedder, T.F.3
-
93
-
-
84876298852
-
Cytokine-producing B cells as regulators of pathogenic and protective immune responses
-
Fillatreau S. Cytokine-producing B cells as regulators of pathogenic and protective immune responses. Ann Rheum Dis (2013) 72(Suppl 2):ii80-4. doi:10.1136/annrheumdis-2012-202253.
-
(2013)
Ann Rheum Dis
, vol.72
, pp. ii80-ii84
-
-
Fillatreau, S.1
-
94
-
-
84897027520
-
IL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases
-
Shen P, Roch T, Lampropoulou V, O'Connor RA, Stervbo U, Hilgenberg E, et al. IL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases. Nature (2014) 507:366-70. doi:10.1038/nature12979.
-
(2014)
Nature
, vol.507
, pp. 366-370
-
-
Shen, P.1
Roch, T.2
Lampropoulou, V.3
O'Connor, R.A.4
Stervbo, U.5
Hilgenberg, E.6
-
95
-
-
0031965144
-
Suppression of immune responses by CD8 cells. II. Qa-1 on activated B cells stimulates CD8 cell suppression of T helper 2 responses
-
Noble A, Zhao ZS, Cantor H. Suppression of immune responses by CD8 cells. II. Qa-1 on activated B cells stimulates CD8 cell suppression of T helper 2 responses. J Immunol (1998) 160:566-71.
-
(1998)
J Immunol
, vol.160
, pp. 566-571
-
-
Noble, A.1
Zhao, Z.S.2
Cantor, H.3
-
96
-
-
1642566833
-
CpG-DNA aided cross-priming by cross-presenting B cells
-
Heit A, Huster KM, Schmitz F, Schiemann M, Busch DH, Wagner H. CpG-DNA aided cross-priming by cross-presenting B cells. J Immunol (2004) 172:1501-7. doi:10.4049/jimmunol.172.3.1501.
-
(2004)
J Immunol
, vol.172
, pp. 1501-1507
-
-
Heit, A.1
Huster, K.M.2
Schmitz, F.3
Schiemann, M.4
Busch, D.H.5
Wagner, H.6
-
97
-
-
84868008849
-
B-cell cross-presentation of autologous antigen precipitates diabetes
-
Marino E, Tan B, Binge L, Mackay CR, Grey ST. B-cell cross-presentation of autologous antigen precipitates diabetes. Diabetes (2012) 61:2893-905. doi:10.2337/db12-0006.
-
(2012)
Diabetes
, vol.61
, pp. 2893-2905
-
-
Marino, E.1
Tan, B.2
Binge, L.3
Mackay, C.R.4
Grey, S.T.5
-
98
-
-
0028785461
-
Role of splenic B cells in the immune privilege of the anterior chamber of the eye
-
Niederkorn JY, Mayhew E. Role of splenic B cells in the immune privilege of the anterior chamber of the eye. Eur J Immunol (1995) 25:2783-7. doi:10.1002/eji.1830251011.
-
(1995)
Eur J Immunol
, vol.25
, pp. 2783-2787
-
-
Niederkorn, J.Y.1
Mayhew, E.2
-
99
-
-
0031661152
-
Splenic B cells are required for tolerogenic antigen presentation in the induction of anterior chamber-associated immune deviation (ACAID)
-
D'Orazio TJ, Niederkorn JY. Splenic B cells are required for tolerogenic antigen presentation in the induction of anterior chamber-associated immune deviation (ACAID). Immunology (1998) 95:47-55. doi:10.1046/j.1365-2567.1998.00581.x.
-
(1998)
Immunology
, vol.95
, pp. 47-55
-
-
D'Orazio, T.J.1
Niederkorn, J.Y.2
-
100
-
-
33646474975
-
Peripheral tolerance via the anterior chamber of the eye: role of B cells in MHC class I and II antigen presentation
-
Ashour HM, Niederkorn JY. Peripheral tolerance via the anterior chamber of the eye: role of B cells in MHC class I and II antigen presentation. J Immunol (2006) 176:5950-7. doi:10.4049/jimmunol.176.10.5950.
-
(2006)
J Immunol
, vol.176
, pp. 5950-5957
-
-
Ashour, H.M.1
Niederkorn, J.Y.2
-
101
-
-
84888074455
-
Role of IL-10-producing regulatory B cells in control of cerebral malaria in Plasmodium berghei infected mice
-
Liu Y, Chen Y, Li Z, Han Y, Sun Y, Wang Q, et al. Role of IL-10-producing regulatory B cells in control of cerebral malaria in Plasmodium berghei infected mice. Eur J Immunol (2013) 43:2907-18. doi:10.1002/eji.201343512.
-
(2013)
Eur J Immunol
, vol.43
, pp. 2907-2918
-
-
Liu, Y.1
Chen, Y.2
Li, Z.3
Han, Y.4
Sun, Y.5
Wang, Q.6
-
102
-
-
84945936980
-
The expanding family of regulatory B cells
-
Mauri C, Menon M. The expanding family of regulatory B cells. Int Immunol (2015) 27:479-86. doi:10.1093/intimm/dxv038.
-
(2015)
Int Immunol
, vol.27
, pp. 479-486
-
-
Mauri, C.1
Menon, M.2
-
103
-
-
84916886831
-
Infiltrating regulatory B cells control neuroinflammation following viral brain infection
-
Mutnal MB, Hu S, Schachtele SJ, Lokensgard JR. Infiltrating regulatory B cells control neuroinflammation following viral brain infection. J Immunol (2014) 193:6070-80. doi:10.4049/jimmunol.1400654.
-
(2014)
J Immunol
, vol.193
, pp. 6070-6080
-
-
Mutnal, M.B.1
Hu, S.2
Schachtele, S.J.3
Lokensgard, J.R.4
-
104
-
-
84922394028
-
Regulatory B cells inhibit cytotoxic T lymphocyte (CTL) activity and elimination of infected CD4 T cells after in vitro reactivation of HIV latent reservoirs
-
Siewe B, Wallace J, Rygielski S, Stapleton JT, Martin J, Deeks SG, et al. Regulatory B cells inhibit cytotoxic T lymphocyte (CTL) activity and elimination of infected CD4 T cells after in vitro reactivation of HIV latent reservoirs. PLoS One (2014) 9:e92934. doi:10.1371/journal.pone.0092934.
-
(2014)
PLoS One
, vol.9
-
-
Siewe, B.1
Wallace, J.2
Rygielski, S.3
Stapleton, J.T.4
Martin, J.5
Deeks, S.G.6
-
105
-
-
84877058009
-
Regulatory B cell frequency correlates with markers of HIV disease progression and attenuates anti-HIV CD8(+) T cell function in vitro
-
Siewe B, Stapleton JT, Martinson J, Keshavarzian A, Kazmi N, Demarais PM, et al. Regulatory B cell frequency correlates with markers of HIV disease progression and attenuates anti-HIV CD8(+) T cell function in vitro. J Leukoc Biol (2013) 93:811-8. doi:10.1189/jlb.0912436.
-
(2013)
J Leukoc Biol
, vol.93
, pp. 811-818
-
-
Siewe, B.1
Stapleton, J.T.2
Martinson, J.3
Keshavarzian, A.4
Kazmi, N.5
Demarais, P.M.6
-
106
-
-
0037140551
-
CD8 T cells are required for the formation of ectopic germinal centers in rheumatoid synovitis
-
Kang YM, Zhang X, Wagner UG, Yang H, Beckenbaugh RD, Kurtin PJ, et al. CD8 T cells are required for the formation of ectopic germinal centers in rheumatoid synovitis. J Exp Med (2002) 195:1325-36. doi:10.1084/jem.20011565.
-
(2002)
J Exp Med
, vol.195
, pp. 1325-1336
-
-
Kang, Y.M.1
Zhang, X.2
Wagner, U.G.3
Yang, H.4
Beckenbaugh, R.D.5
Kurtin, P.J.6
-
107
-
-
0037307855
-
A specific role for B cells in the generation of CD8 T cell memory by recombinant Listeria monocytogenes
-
Shen H, Whitmire JK, Fan X, Shedlock DJ, Kaech SM, Ahmed R. A specific role for B cells in the generation of CD8 T cell memory by recombinant Listeria monocytogenes. J Immunol (2003) 170:1443-51. doi:10.4049/jimmunol.170.3.1443.
-
(2003)
J Immunol
, vol.170
, pp. 1443-1451
-
-
Shen, H.1
Whitmire, J.K.2
Fan, X.3
Shedlock, D.J.4
Kaech, S.M.5
Ahmed, R.6
-
108
-
-
13844320401
-
Mesenteric B cells centrally inhibit CD4+ T cell colitis through interaction with regulatory T cell subsets
-
Wei B, Velazquez P, Turovskaya O, Spricher K, Aranda R, Kronenberg M, et al. Mesenteric B cells centrally inhibit CD4+ T cell colitis through interaction with regulatory T cell subsets. Proc Natl Acad Sci USA (2005) 102:2010-5. doi:10.1073/pnas.0409449102.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 2010-2015
-
-
Wei, B.1
Velazquez, P.2
Turovskaya, O.3
Spricher, K.4
Aranda, R.5
Kronenberg, M.6
-
109
-
-
37549071024
-
CXCR5+ CCR7- CD8 T cells are early effector memory cells that infiltrate tonsil B cell follicles
-
Quigley MF, Gonzalez VD, Granath A, Andersson J, Sandberg JK. CXCR5+ CCR7- CD8 T cells are early effector memory cells that infiltrate tonsil B cell follicles. Eur J Immunol (2007) 37:3352-62. doi:10.1002/eji.200636746.
-
(2007)
Eur J Immunol
, vol.37
, pp. 3352-3362
-
-
Quigley, M.F.1
Gonzalez, V.D.2
Granath, A.3
Andersson, J.4
Sandberg, J.K.5
-
110
-
-
40749131713
-
Helper B cells promote cytotoxic T cell survival and proliferation independently of antigen presentation through CD27/CD70 interactions
-
Deola S, Panelli MC, Maric D, Selleri S, Dmitrieva NI, Voss CY, et al. Helper B cells promote cytotoxic T cell survival and proliferation independently of antigen presentation through CD27/CD70 interactions. J Immunol (2008) 180:1362-72. doi:10.4049/jimmunol.180.3.1362.
-
(2008)
J Immunol
, vol.180
, pp. 1362-1372
-
-
Deola, S.1
Panelli, M.C.2
Maric, D.3
Selleri, S.4
Dmitrieva, N.I.5
Voss, C.Y.6
-
111
-
-
45249115068
-
Integration of B cells and CD8+ T in the protective regulation of systemic epithelial inflammation
-
Wei B, McPherson M, Turovskaya O, Velazquez P, Fujiwara D, Brewer S, et al. Integration of B cells and CD8+ T in the protective regulation of systemic epithelial inflammation. Clin Immunol (2008) 127:303-12. doi:10.1016/j.clim.2008.01.001.
-
(2008)
Clin Immunol
, vol.127
, pp. 303-312
-
-
Wei, B.1
McPherson, M.2
Turovskaya, O.3
Velazquez, P.4
Fujiwara, D.5
Brewer, S.6
-
112
-
-
0020962424
-
Multiple sclerosis. Distribution of T cells, T cell subsets and Ia-positive macrophages in lesions of different ages
-
Traugott U, Reinherz EL, Raine CS. Multiple sclerosis. Distribution of T cells, T cell subsets and Ia-positive macrophages in lesions of different ages. J Neuroimmunol (1983) 4:201-21. doi:10.1016/0165-5728(83)90036-X.
-
(1983)
J Neuroimmunol
, vol.4
, pp. 201-221
-
-
Traugott, U.1
Reinherz, E.L.2
Raine, C.S.3
-
113
-
-
0022459287
-
Immunohistochemical analysis of the cellular infiltrate in multiple sclerosis lesions
-
Hauser SL, Bhan AK, Gilles F, Kemp M, Kerr C, Weiner HL. Immunohistochemical analysis of the cellular infiltrate in multiple sclerosis lesions. Ann Neurol (1986) 19:578-87. doi:10.1002/ana.410190610.
-
(1986)
Ann Neurol
, vol.19
, pp. 578-587
-
-
Hauser, S.L.1
Bhan, A.K.2
Gilles, F.3
Kemp, M.4
Kerr, C.5
Weiner, H.L.6
-
114
-
-
1842423766
-
Increased CD8+ cytotoxic T cell responses to myelin basic protein in multiple sclerosis
-
Zang YC, Li S, Rivera VM, Hong J, Robinson RR, Breitbach WT, et al. Increased CD8+ cytotoxic T cell responses to myelin basic protein in multiple sclerosis. J Immunol (2004) 172:5120-7. doi:10.4049/jimmunol.172.8.5120.
-
(2004)
J Immunol
, vol.172
, pp. 5120-5127
-
-
Zang, Y.C.1
Li, S.2
Rivera, V.M.3
Hong, J.4
Robinson, R.R.5
Breitbach, W.T.6
-
115
-
-
27644552194
-
Cortical demyelination and diffuse white matter injury in multiple sclerosis
-
Kutzelnigg A, Lucchinetti CF, Stadelmann C, Bruck W, Rauschka H, Bergmann M, et al. Cortical demyelination and diffuse white matter injury in multiple sclerosis. Brain (2005) 128:2705-12. doi:10.1093/brain/awh641.
-
(2005)
Brain
, vol.128
, pp. 2705-2712
-
-
Kutzelnigg, A.1
Lucchinetti, C.F.2
Stadelmann, C.3
Bruck, W.4
Rauschka, H.5
Bergmann, M.6
-
116
-
-
0032521030
-
MHC class I-restricted lysis of human oligodendrocytes by myelin basic protein peptide-specific CD8 T lymphocytes
-
Jurewicz A, Biddison WE, Antel JP. MHC class I-restricted lysis of human oligodendrocytes by myelin basic protein peptide-specific CD8 T lymphocytes. J Immunol (1998) 160:3056-9.
-
(1998)
J Immunol
, vol.160
, pp. 3056-3059
-
-
Jurewicz, A.1
Biddison, W.E.2
Antel, J.P.3
-
117
-
-
33947509525
-
The immunopathology of multiple sclerosis: an overview
-
Lassmann H, Bruck W, Lucchinetti CF. The immunopathology of multiple sclerosis: an overview. Brain Pathol (2007) 17:210-8. doi:10.1111/j.1750-3639.2007.00064.x.
-
(2007)
Brain Pathol
, vol.17
, pp. 210-218
-
-
Lassmann, H.1
Bruck, W.2
Lucchinetti, C.F.3
-
118
-
-
0036602982
-
Cytotoxic T lymphocytes in autoimmune and degenerative CNS diseases
-
Neumann H, Medana IM, Bauer J, Lassmann H. Cytotoxic T lymphocytes in autoimmune and degenerative CNS diseases. Trends Neurosci (2002) 25:313-9. doi:10.1016/S0166-2236(02)02154-9.
-
(2002)
Trends Neurosci
, vol.25
, pp. 313-319
-
-
Neumann, H.1
Medana, I.M.2
Bauer, J.3
Lassmann, H.4
-
119
-
-
33645022328
-
Dendritic cells in multiple sclerosis lesions: maturation stage, myelin uptake, and interaction with proliferating T cells
-
Serafini B, Rosicarelli B, Magliozzi R, Stigliano E, Capello E, Mancardi GL, et al. Dendritic cells in multiple sclerosis lesions: maturation stage, myelin uptake, and interaction with proliferating T cells. J Neuropathol Exp Neurol (2006) 65:124-41. doi:10.1097/01.jnen.0000199572.96472.1c.
-
(2006)
J Neuropathol Exp Neurol
, vol.65
, pp. 124-141
-
-
Serafini, B.1
Rosicarelli, B.2
Magliozzi, R.3
Stigliano, E.4
Capello, E.5
Mancardi, G.L.6
-
120
-
-
1042299971
-
Expression of major histocompatibility complex class I molecules on the different cell types in multiple sclerosis lesions
-
Hoftberger R, Aboul-Enein F, Brueck W, Lucchinetti C, Rodriguez M, Schmidbauer M, et al. Expression of major histocompatibility complex class I molecules on the different cell types in multiple sclerosis lesions. Brain Pathol (2004) 14:43-50. doi:10.1111/j.1750-3639.2004.tb00496.x.
-
(2004)
Brain Pathol
, vol.14
, pp. 43-50
-
-
Hoftberger, R.1
Aboul-Enein, F.2
Brueck, W.3
Lucchinetti, C.4
Rodriguez, M.5
Schmidbauer, M.6
-
121
-
-
0027630974
-
Cell type-specific regulation of major histocompatibility complex (MHC) class I gene expression in astrocytes, oligodendrocytes, and neurons
-
Massa PT, Ozato K, McFarlin DE. Cell type-specific regulation of major histocompatibility complex (MHC) class I gene expression in astrocytes, oligodendrocytes, and neurons. Glia (1993) 8:201-7. doi:10.1002/glia.440080307.
-
(1993)
Glia
, vol.8
, pp. 201-207
-
-
Massa, P.T.1
Ozato, K.2
McFarlin, D.E.3
-
122
-
-
34548387020
-
An antigen-specific pathway for CD8 T cells across the blood-brain barrier
-
Galea I, Bernardes-Silva M, Forse PA, van Rooijen N, Liblau RS, Perry VH. An antigen-specific pathway for CD8 T cells across the blood-brain barrier. J Exp Med (2007) 204:2023-30. doi:10.1084/jem.20070064.
-
(2007)
J Exp Med
, vol.204
, pp. 2023-2030
-
-
Galea, I.1
Bernardes-Silva, M.2
Forse, P.A.3
van Rooijen, N.4
Liblau, R.S.5
Perry, V.H.6
-
123
-
-
0034026912
-
Acute axonal injury in multiple sclerosis. Correlation with demyelination and inflammation
-
Bitsch A, Schuchardt J, Bunkowski S, Kuhlmann T, Bruck W. Acute axonal injury in multiple sclerosis. Correlation with demyelination and inflammation. Brain (2000) 123(Pt 6):1174-83. doi:10.1093/brain/123.6.1174.
-
(2000)
Brain
, vol.123
, pp. 1174-1183
-
-
Bitsch, A.1
Schuchardt, J.2
Bunkowski, S.3
Kuhlmann, T.4
Bruck, W.5
-
124
-
-
0031573209
-
Autoantigen recognition by human CD8 T cell clones: enhanced agonist response induced by altered peptide ligands
-
Dressel A, Chin JL, Sette A, Gausling R, Hollsberg P, Hafler DA. Autoantigen recognition by human CD8 T cell clones: enhanced agonist response induced by altered peptide ligands. J Immunol (1997) 159:4943-51.
-
(1997)
J Immunol
, vol.159
, pp. 4943-4951
-
-
Dressel, A.1
Chin, J.L.2
Sette, A.3
Gausling, R.4
Hollsberg, P.5
Hafler, D.A.6
-
125
-
-
0028143869
-
Autoreactive CD8+ T-cell responses to human myelin protein-derived peptides
-
Tsuchida T, Parker KC, Turner RV, McFarland HF, Coligan JE, Biddison WE. Autoreactive CD8+ T-cell responses to human myelin protein-derived peptides. Proc Natl Acad Sci U S A (1994) 91:10859-63. doi:10.1073/pnas.91.23.10859.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 10859-10863
-
-
Tsuchida, T.1
Parker, K.C.2
Turner, R.V.3
McFarland, H.F.4
Coligan, J.E.5
Biddison, W.E.6
-
126
-
-
84880853642
-
Increased CD8+ T cell responses to apoptotic T cell-associated antigens in multiple sclerosis
-
Lolli F, Martini H, Citro A, Franceschini D, Portaccio E, Amato MP, et al. Increased CD8+ T cell responses to apoptotic T cell-associated antigens in multiple sclerosis. J Neuroinflammation (2013) 10:94. doi:10.1186/1742-2094-10-94.
-
(2013)
J Neuroinflammation
, vol.10
, pp. 94
-
-
Lolli, F.1
Martini, H.2
Citro, A.3
Franceschini, D.4
Portaccio, E.5
Amato, M.P.6
-
127
-
-
10744233874
-
CD8+ T cells from patients with acute multiple sclerosis display selective increase of adhesiveness in brain venules: a critical role for P-selectin glycoprotein ligand-1
-
Battistini L, Piccio L, Rossi B, Bach S, Galgani S, Gasperini C, et al. CD8+ T cells from patients with acute multiple sclerosis display selective increase of adhesiveness in brain venules: a critical role for P-selectin glycoprotein ligand-1. Blood (2003) 101:4775-82. doi:10.1182/blood-2002-10-3309.
-
(2003)
Blood
, vol.101
, pp. 4775-4782
-
-
Battistini, L.1
Piccio, L.2
Rossi, B.3
Bach, S.4
Galgani, S.5
Gasperini, C.6
-
128
-
-
38749143286
-
Interleukin-17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis
-
Tzartos JS, Friese MA, Craner MJ, Palace J, Newcombe J, Esiri MM, et al. Interleukin-17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis. Am J Pathol (2008) 172:146-55. doi:10.2353/ajpath.2008.070690.
-
(2008)
Am J Pathol
, vol.172
, pp. 146-155
-
-
Tzartos, J.S.1
Friese, M.A.2
Craner, M.J.3
Palace, J.4
Newcombe, J.5
Esiri, M.M.6
-
129
-
-
79551700235
-
CD161(high)CD8+ T cells bear pathogenetic potential in multiple sclerosis
-
Annibali V, Ristori G, Angelini DF, Serafini B, Mechelli R, Cannoni S, et al. CD161(high)CD8+ T cells bear pathogenetic potential in multiple sclerosis. Brain (2011) 134:542-54. doi:10.1093/brain/awq354.
-
(2011)
Brain
, vol.134
, pp. 542-554
-
-
Annibali, V.1
Ristori, G.2
Angelini, D.F.3
Serafini, B.4
Mechelli, R.5
Cannoni, S.6
-
130
-
-
83555176375
-
Circulating CD8+CD56-perforin+ T cells are increased in multiple sclerosis patients
-
Giovanni F, Domenico P, Alessandro M, Raffaele I, Viviana N, Katia PA, et al. Circulating CD8+CD56-perforin+ T cells are increased in multiple sclerosis patients. J Neuroimmunol (2011) 24(0-241):137-41. doi:10.1016/j.jneuroim.2011.09.002.
-
(2011)
J Neuroimmunol
, vol.24
, Issue.241
, pp. 137-141
-
-
Giovanni, F.1
Domenico, P.2
Alessandro, M.3
Raffaele, I.4
Viviana, N.5
Katia, P.A.6
-
131
-
-
0022476268
-
Comparison of T8+ cell-mediated suppressor and cytotoxic functions in multiple sclerosis
-
Antel JP, Nicholas MK, Bania MB, Reder AT, Arnason BG, Joseph L. Comparison of T8+ cell-mediated suppressor and cytotoxic functions in multiple sclerosis. J Neuroimmunol (1986) 12:215-24. doi:10.1016/S0165-5728(86)80005-4.
-
(1986)
J Neuroimmunol
, vol.12
, pp. 215-224
-
-
Antel, J.P.1
Nicholas, M.K.2
Bania, M.B.3
Reder, A.T.4
Arnason, B.G.5
Joseph, L.6
-
132
-
-
0029075492
-
Inhibition of T cell responses by activated human CD8+ T cells is mediated by interferon-gamma and is defective in chronic progressive multiple sclerosis
-
Balashov KE, Khoury SJ, Hafler DA, Weiner HL. Inhibition of T cell responses by activated human CD8+ T cells is mediated by interferon-gamma and is defective in chronic progressive multiple sclerosis. J Clin Invest (1995) 95:2711-9. doi:10.1172/JCI117973.
-
(1995)
J Clin Invest
, vol.95
, pp. 2711-2719
-
-
Balashov, K.E.1
Khoury, S.J.2
Hafler, D.A.3
Weiner, H.L.4
-
133
-
-
17844363998
-
Defects in CD8+ regulatory T cells in the lamina propria of patients with inflammatory bowel disease
-
Brimnes J, Allez M, Dotan I, Shao L, Nakazawa A, Mayer L. Defects in CD8+ regulatory T cells in the lamina propria of patients with inflammatory bowel disease. J Immunol (2005) 174:5814-22. doi:10.4049/jimmunol.174.9.5814.
-
(2005)
J Immunol
, vol.174
, pp. 5814-5822
-
-
Brimnes, J.1
Allez, M.2
Dotan, I.3
Shao, L.4
Nakazawa, A.5
Mayer, L.6
-
134
-
-
84863986199
-
Characterization of effector memory CD8+ T cells in the synovial fluid of rheumatoid arthritis
-
Cho BA, Sim JH, Park JA, Kim HW, Yoo WH, Lee SH, et al. Characterization of effector memory CD8+ T cells in the synovial fluid of rheumatoid arthritis. J Clin Immunol (2012) 32:709-20. doi:10.1007/s10875-012-9674-3.
-
(2012)
J Clin Immunol
, vol.32
, pp. 709-720
-
-
Cho, B.A.1
Sim, J.H.2
Park, J.A.3
Kim, H.W.4
Yoo, W.H.5
Lee, S.H.6
-
135
-
-
77950867022
-
Numerical defects in CD8+CD28- T-suppressor lymphocyte population in patients with type 1 diabetes mellitus and multiple sclerosis
-
Mikulkova Z, Praksova P, Stourac P, Bednarik J, Strajtova L, Pacasova R, et al. Numerical defects in CD8+CD28- T-suppressor lymphocyte population in patients with type 1 diabetes mellitus and multiple sclerosis. Cell Immunol (2010) 262:75-9. doi:10.1016/j.cellimm.2010.02.002.
-
(2010)
Cell Immunol
, vol.262
, pp. 75-79
-
-
Mikulkova, Z.1
Praksova, P.2
Stourac, P.3
Bednarik, J.4
Strajtova, L.5
Pacasova, R.6
-
136
-
-
77953624351
-
TLR2 agonists enhance CD8+Foxp3+ regulatory T cells and suppress Th2 immune responses during allergen immunotherapy
-
Tsai YG, Yang KD, Niu DM, Chien JW, Lin CY. TLR2 agonists enhance CD8+Foxp3+ regulatory T cells and suppress Th2 immune responses during allergen immunotherapy. J Immunol (2010) 184:7229-37. doi:10.4049/jimmunol.1000083.
-
(2010)
J Immunol
, vol.184
, pp. 7229-7237
-
-
Tsai, Y.G.1
Yang, K.D.2
Niu, D.M.3
Chien, J.W.4
Lin, C.Y.5
-
137
-
-
77951712594
-
Role of CD8+ CD25+ Foxp3+ regulatory T cells in multiple sclerosis
-
Correale J, Villa A. Role of CD8+ CD25+ Foxp3+ regulatory T cells in multiple sclerosis. Ann Neurol (2010) 67:625-38. doi:10.1002/ana.21944.
-
(2010)
Ann Neurol
, vol.67
, pp. 625-638
-
-
Correale, J.1
Villa, A.2
-
138
-
-
77951939525
-
CD8(+)Foxp3(+) T cells in peripheral blood of relapsing-remitting multiple sclerosis patients
-
Frisullo G, Nociti V, Iorio R, Plantone D, Patanella AK, Tonali PA, et al. CD8(+)Foxp3(+) T cells in peripheral blood of relapsing-remitting multiple sclerosis patients. Hum Immunol (2010) 71:437-41. doi:10.1016/j.humimm.2010.01.024.
-
(2010)
Hum Immunol
, vol.71
, pp. 437-441
-
-
Frisullo, G.1
Nociti, V.2
Iorio, R.3
Plantone, D.4
Patanella, A.K.5
Tonali, P.A.6
-
139
-
-
70249127941
-
Human CD8+CXCR3+ T cells have the same function as murine CD8+CD122+ Treg
-
Shi Z, Okuno Y, Rifa'i M, Endharti AT, Akane K, Isobe K, et al. Human CD8+CXCR3+ T cells have the same function as murine CD8+CD122+ Treg. Eur J Immunol (2009) 39:2106-19. doi:10.1002/eji.200939314.
-
(2009)
Eur J Immunol
, vol.39
, pp. 2106-2119
-
-
Shi, Z.1
Okuno, Y.2
Rifa'i, M.3
Endharti, A.T.4
Akane, K.5
Isobe, K.6
-
140
-
-
77957855176
-
HLA-E-restricted regulatory CD8(+) T cells are involved in development and control of human autoimmune type 1 diabetes
-
Jiang H, Canfield SM, Gallagher MP, Jiang HH, Jiang Y, Zheng Z, et al. HLA-E-restricted regulatory CD8(+) T cells are involved in development and control of human autoimmune type 1 diabetes. J Clin Invest (2010) 120:3641-50. doi:10.1172/JCI43522.
-
(2010)
J Clin Invest
, vol.120
, pp. 3641-3650
-
-
Jiang, H.1
Canfield, S.M.2
Gallagher, M.P.3
Jiang, H.H.4
Jiang, Y.5
Zheng, Z.6
-
141
-
-
54349094927
-
Expansion of regulatory CD8+ T-lymphocytes and fall of activated CD8+ T-lymphocytes after i.v. methyl-prednisolone for multiple sclerosis relapse
-
Aristimuno C, Navarro J, de Andres C, Martinez-Gines L, Gimenez-Roldan S, Fernandez-Cruz E, et al. Expansion of regulatory CD8+ T-lymphocytes and fall of activated CD8+ T-lymphocytes after i.v. methyl-prednisolone for multiple sclerosis relapse. J Neuroimmunol (2008) 204:131-5. doi:10.1016/j.jneuroim.2008.08.009.
-
(2008)
J Neuroimmunol
, vol.204
, pp. 131-135
-
-
Aristimuno, C.1
Navarro, J.2
de Andres, C.3
Martinez-Gines, L.4
Gimenez-Roldan, S.5
Fernandez-Cruz, E.6
-
142
-
-
41949135382
-
Isolation and characterization of CD8+ regulatory T cells in multiple sclerosis
-
Correale J, Villa A. Isolation and characterization of CD8+ regulatory T cells in multiple sclerosis. J Neuroimmunol (2008) 195:121-34. doi:10.1016/j.jneuroim.2007.12.004.
-
(2008)
J Neuroimmunol
, vol.195
, pp. 121-134
-
-
Correale, J.1
Villa, A.2
-
143
-
-
77949354716
-
99th Dahlem conference on infection, inflammation and chronic inflammatory disorders: Epstein-Barr virus and multiple sclerosis: epidemiological evidence
-
Ascherio A, Munger KL. 99th Dahlem conference on infection, inflammation and chronic inflammatory disorders: Epstein-Barr virus and multiple sclerosis: epidemiological evidence. Clin Exp Immunol (2010) 160:120-4. doi:10.1111/j.1365-2249.2010.04121.x.
-
(2010)
Clin Exp Immunol
, vol.160
, pp. 120-124
-
-
Ascherio, A.1
Munger, K.L.2
-
144
-
-
46849084346
-
Strong EBV-specific CD8+ T-cell response in patients with early multiple sclerosis
-
Jilek S, Schluep M, Meylan P, Vingerhoets F, Guignard L, Monney A, et al. Strong EBV-specific CD8+ T-cell response in patients with early multiple sclerosis. Brain (2008) 131:1712-21. doi:10.1093/brain/awn108.
-
(2008)
Brain
, vol.131
, pp. 1712-1721
-
-
Jilek, S.1
Schluep, M.2
Meylan, P.3
Vingerhoets, F.4
Guignard, L.5
Monney, A.6
-
145
-
-
84917740296
-
High-throughput sequencing of TCR repertoires in multiple sclerosis reveals intrathecal enrichment of EBV-reactive CD8+ T cells
-
Lossius A, Johansen JN, Vartdal F, Robins H, Jurate Saltyte B, Holmoy T, et al. High-throughput sequencing of TCR repertoires in multiple sclerosis reveals intrathecal enrichment of EBV-reactive CD8+ T cells. Eur J Immunol (2014) 44:3439-52. doi:10.1002/eji.201444662.
-
(2014)
Eur J Immunol
, vol.44
, pp. 3439-3452
-
-
Lossius, A.1
Johansen, J.N.2
Vartdal, F.3
Robins, H.4
Jurate Saltyte, B.5
Holmoy, T.6
-
146
-
-
84904639472
-
Epstein-Barr virus-specific adoptive immunotherapy: a new horizon for multiple sclerosis treatment?
-
Pender MP, Khanna R. Epstein-Barr virus-specific adoptive immunotherapy: a new horizon for multiple sclerosis treatment? Immunotherapy (2014) 6:659-61. doi:10.2217/imt.14.43.
-
(2014)
Immunotherapy
, vol.6
, pp. 659-661
-
-
Pender, M.P.1
Khanna, R.2
-
147
-
-
84874826127
-
Cytotoxic NKG2C+ CD4 T cells target oligodendrocytes in multiple sclerosis
-
Zaguia F, Saikali P, Ludwin S, Newcombe J, Beauseigle D, McCrea E, et al. Cytotoxic NKG2C+ CD4 T cells target oligodendrocytes in multiple sclerosis. J Immunol (2013) 190:2510-8. doi:10.4049/jimmunol.1202725.
-
(2013)
J Immunol
, vol.190
, pp. 2510-2518
-
-
Zaguia, F.1
Saikali, P.2
Ludwin, S.3
Newcombe, J.4
Beauseigle, D.5
McCrea, E.6
-
148
-
-
73349129340
-
IFNbeta-1a therapy for multiple sclerosis expands regulatory CD8+ T cells and decreases memory CD8+ subset: a longitudinal 1-year study
-
Aristimuno C, de Andres C, Bartolome M, de las Heras V, Martinez-Gines ML, Arroyo R, et al. IFNbeta-1a therapy for multiple sclerosis expands regulatory CD8+ T cells and decreases memory CD8+ subset: a longitudinal 1-year study. Clin Immunol (2010) 134:148-57. doi:10.1016/j.clim.2009.09.008.
-
(2010)
Clin Immunol
, vol.134
, pp. 148-157
-
-
Aristimuno, C.1
de Andres, C.2
Bartolome, M.3
de las Heras, V.4
Martinez-Gines, M.L.5
Arroyo, R.6
-
149
-
-
84871695430
-
Immune response during interferon beta-1b treatment in patients with multiple sclerosis who experienced relapses and those who were relapse-free in the START study
-
Dhib-Jalbut S, Sumandeep S, Valenzuela R, Ito K, Patel P, Rametta M. Immune response during interferon beta-1b treatment in patients with multiple sclerosis who experienced relapses and those who were relapse-free in the START study. J Neuroimmunol (2013) 254:131-40. doi:10.1016/j.jneuroim.2012.08.012.
-
(2013)
J Neuroimmunol
, vol.254
, pp. 131-140
-
-
Dhib-Jalbut, S.1
Sumandeep, S.2
Valenzuela, R.3
Ito, K.4
Patel, P.5
Rametta, M.6
-
150
-
-
84891371436
-
Fingolimod modulates peripheral effector and regulatory T cells in MS patients
-
Serpero LD, Filaci G, Parodi A, Battaglia F, Kalli F, Brogi D, et al. Fingolimod modulates peripheral effector and regulatory T cells in MS patients. J Neuroimmune Pharmacol (2013) 8:1106-13. doi:10.1007/s11481-013-9465-5.
-
(2013)
J Neuroimmune Pharmacol
, vol.8
, pp. 1106-1113
-
-
Serpero, L.D.1
Filaci, G.2
Parodi, A.3
Battaglia, F.4
Kalli, F.5
Brogi, D.6
-
151
-
-
33749588466
-
Altered CD4+/CD8+ T-cell ratios in cerebrospinal fluid of natalizumab-treated patients with multiple sclerosis
-
Stuve O, Marra CM, Bar-Or A, Niino M, Cravens PD, Cepok S, et al. Altered CD4+/CD8+ T-cell ratios in cerebrospinal fluid of natalizumab-treated patients with multiple sclerosis. Arch Neurol (2006) 63:1383-7. doi:10.1001/archneur.63.10.1383.
-
(2006)
Arch Neurol
, vol.63
, pp. 1383-1387
-
-
Stuve, O.1
Marra, C.M.2
Bar-Or, A.3
Niino, M.4
Cravens, P.D.5
Cepok, S.6
|