High-throughput sequencing of TCR repertoires in multiple sclerosis reveals intrathecal enrichment of EBV-reactive CD8+ T cells

European Journal of Immunology

Volumn 44, Issue 11, 2014, Pages 3439-3452

  Lossius, Andreas ^a,b   Johansen, Jorunn N ^a   Vartdal, Frode ^a,b   Robins, Harlan ^c   Šaltyte, Benth Jurate ^b,d   Holmøy, Trygve ^b,d   Olweus, Johanna ^a,b  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

^b UNIVERSITY OF OSLO   (Norway)

^c Fred Hutchinson Cancer Research Center   (United States)

^d AKERSHUS UNIVERSITY HOSPITAL   (Norway)

Author keywords

Cerebrospinal fluid; Epstein Barr virus; High throughput sequencing; MS; TCR

Indexed keywords

T LYMPHOCYTE RECEPTOR; HLA A ANTIGEN; HLA B ANTIGEN; HLA DRB1 ANTIGEN; LYMPHOCYTE ANTIGEN RECEPTOR;

ADULT; AMINO ACID SEQUENCE; ANTIBODY TITER; ARTICLE; CD8+ T LYMPHOCYTE; CELL CLONE; CELL EXPANSION; CEREBROSPINAL FLUID ANALYSIS; CLINICAL ARTICLE; CONTROLLED STUDY; EPSTEIN BARR VIRUS; FEMALE; HIGH THROUGHPUT SEQUENCING; HLA SYSTEM; HUMAN; MALE; MIDDLE AGED; MOLECULAR LIBRARY; MONONUCLEOSIS; MULTIPLE SCLEROSIS; SEQUENCE ANALYSIS; T LYMPHOCYTE SUBPOPULATION; YOUNG ADULT; B LYMPHOCYTE; BLOOD; CD4+ T LYMPHOCYTE; CEREBROSPINAL FLUID; DNA SEQUENCE; GENETICS; IMMUNOLOGY; NUCLEOTIDE SEQUENCE; VIROLOGY;

ADULT; B-LYMPHOCYTES; BASE SEQUENCE; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; FEMALE; HERPESVIRUS 4, HUMAN; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HLA-A ANTIGENS; HLA-B ANTIGENS; HLA-DRB1 CHAINS; HUMANS; INFECTIOUS MONONUCLEOSIS; MALE; MIDDLE AGED; MULTIPLE SCLEROSIS; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; SEQUENCE ANALYSIS, DNA; YOUNG ADULT;

EID: 84917740296     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201444662     Document Type: Article

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