메뉴 건너뛰기




Volumn 491, Issue 7423, 2012, Pages 264-268

Regulatory B cells control T-cell autoimmunity through IL-21-dependent cognate interactions

Author keywords

[No Author keywords available]

Indexed keywords

CD40 ANTIGEN; INTERLEUKIN 21;

EID: 84868619716     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature11501     Document Type: Article
Times cited : (538)

References (37)
  • 1
    • 47249099558 scopus 로고    scopus 로고
    • B-lymphocytes: How they develop and function
    • LeBien, T. W.& Tedder, T. F. B-lymphocytes: how they develop and function. Blood 112, 1570-1580 (2008).
    • (2008) Blood , vol.112 , pp. 1570-1580
    • Lebien, T.W.1    Tedder, T.F.2
  • 2
    • 75749087574 scopus 로고    scopus 로고
    • B10 cells and regulatory B cells balance immune responses during inflammation, autoimmunity, and cancer
    • DiLillo, D. J., Matsushita, T. & Tedder, T. F. B10 cells and regulatory B cells balance immune responses during inflammation, autoimmunity, and cancer. Ann. NY Acad. Sci. 1183, 38-57 (2010).
    • (2010) Ann. NY Acad. Sci , vol.1183 , pp. 38-57
    • Dilillo, D.J.1    Matsushita, T.2    Tedder, T.F.3
  • 3
    • 79951915895 scopus 로고    scopus 로고
    • Novel regulatory functions for Toll-like receptor-activated B cells during intracellular bacterial infection
    • Fillatreau, S. Novel regulatory functions for Toll-like receptor-activated B cells during intracellular bacterial infection. Immunol. Rev. 240, 52-71 (2011).
    • (2011) Immunol. Rev , vol.240 , pp. 52-71
    • Fillatreau, S.1
  • 4
    • 78649894129 scopus 로고    scopus 로고
    • Regulation of immunity and autoimmunity by B cells
    • Mauri, C. Regulation of immunity and autoimmunity by B cells. Curr. Opin. Immunol. 22, 761-767 (2010).
    • (2010) Curr. Opin. Immunol , vol.22 , pp. 761-767
    • Mauri, C.1
  • 5
    • 78751469622 scopus 로고    scopus 로고
    • Characterization of a rare IL-10-competent B cell subset in humans that parallels mouse regulatory B10 cells
    • Iwata, Y. et al. Characterization of a rare IL-10-competent B cell subset in humans that parallels mouse regulatory B10 cells. Blood 117, 530-541 (2011).
    • (2011) Blood , vol.117 , pp. 530-541
    • Iwata, Y.1
  • 6
    • 43049156086 scopus 로고    scopus 로고
    • A regulatory B cell subset with a unique CD1dhiCD51 phenotype controls T cell-dependent inflammatory responses
    • Yanaba, K. et al. A regulatory B cell subset with a unique CD1dhiCD51 phenotype controls T cell-dependent inflammatory responses. Immunity 28, 639-650 (2008).
    • (2008) Immunity , vol.28 , pp. 639-650
    • Yanaba, K.1
  • 7
    • 54949141219 scopus 로고    scopus 로고
    • Regulatory B cells inhibit EAE initiation in mice while other B cells promote disease progression
    • Matsushita, T., Yanaba, K., Bouaziz, J.-D., Fujimoto, M. & Tedder, T. F. Regulatory B cells inhibit EAE initiation in mice while other B cells promote disease progression. J. Clin. Invest. 118, 3420-3430 (2008).
    • (2008) J. Clin. Invest , vol.118 , pp. 3420-3430
    • Matsushita, T.1    Yanaba, K.2    Bouaziz, J.-D.3    Fujimoto, M.4    Tedder, T.F.5
  • 8
    • 84859376769 scopus 로고    scopus 로고
    • A novel IL-10-independent regulatory role for B cells in suppressing autoimmunity by maintenance of regulatory T cells via GITR ligand
    • Ray, A., Basu, S., Williams, C. B., Salzman, N. H. & Dittel, B. N. A novel IL-10-independent regulatory role for B cells in suppressing autoimmunity by maintenance of regulatory T cells via GITR ligand. J. Immunol. 188, 3188-3198 (2012).
    • (2012) J. Immunol , vol.188 , pp. 3188-3198
    • Ray, A.1    Basu, S.2    Williams, C.B.3    Salzman, N.H.4    Dittel, B.N.5
  • 9
    • 67649235672 scopus 로고    scopus 로고
    • The development and function of regulatory B cells expressing IL-10 (B10 cells) requires antigen receptor diversity and TLR signals
    • Yanaba, K., Bouaziz, J.-D., Matsushita, T., Tsubata, T. & Tedder, T. F. The development and function of regulatory B cells expressing IL-10 (B10 cells) requires antigen receptor diversity and TLR signals. J. Immunol. 182, 7459-7472 (2009).
    • (2009) J. Immunol , vol.182 , pp. 7459-7472
    • Yanaba, K.1    Bouaziz, J.-D.2    Matsushita, T.3    Tsubata, T.4    Tedder, T.F.5
  • 10
    • 77954473511 scopus 로고    scopus 로고
    • Protective and pathogenic roles for B cells during systemic autoimmunity in NZB/W F1 mice
    • Haas, K. M. et al. Protective and pathogenic roles for B cells during systemic autoimmunity in NZB/W F1 mice. J. Immunol. 184, 4789-4800 (2010).
    • (2010) J. Immunol , vol.184 , pp. 4789-4800
    • Haas, K.M.1
  • 11
    • 77956895769 scopus 로고    scopus 로고
    • Regulatory B cells (B10 cells) andregulatory T cells have independent roles in controlling EAE initiation and latephase immunopathogenesis
    • Matsushita, T., Horikawa, M., Iwata, Y. & Tedder, T. F. Regulatory B cells (B10 cells) andregulatory T cells have independent roles in controlling EAE initiation and latephase immunopathogenesis. J. Immunol. 185, 2240-2252 (2010).
    • (2010) J. Immunol , vol.185 , pp. 2240-2252
    • Matsushita, T.1    Horikawa, M.2    Iwata, Y.3    Tedder, T.F.4
  • 12
    • 80555124922 scopus 로고    scopus 로고
    • Regulatory B cell production of IL-10 inhibits lymphomadepletion duringCD20immunotherapy in mice
    • Horikawa, M., Minard-Colin, V., Matsushita, T. & Tedder, T. F. Regulatory B cell production of IL-10 inhibits lymphomadepletion duringCD20immunotherapy in mice. J. Clin. Invest. 121, 4268-4280 (2011).
    • (2011) J. Clin. Invest , vol.121 , pp. 4268-4280
    • Horikawa, M.1    Minard-Colin, V.2    Matsushita, T.3    Tedder, T.F.4
  • 13
    • 84863062372 scopus 로고    scopus 로고
    • Regulatory B10 cells differentiate into antibody-secreting cells after transient IL-10 production in vivo
    • Maseda, D. et al. Regulatory B10 cells differentiate into antibody-secreting cells after transient IL-10 production in vivo. J. Immunol. 188, 1036-1048 (2012).
    • (2012) J. Immunol , vol.188 , pp. 1036-1048
    • Maseda, D.1
  • 14
    • 77949895721 scopus 로고    scopus 로고
    • IL-21and T follicular helper cells
    • Spolski, R.&Leonard, W. J. IL-21and T follicular helper cells. Int.Immunol. 22, 7-12 (2009).
    • (2009) Int.Immunol , vol.22 , pp. 7-12
    • Spolski, R.1    Leonard, W.J.2
  • 15
    • 77958138084 scopus 로고    scopus 로고
    • T follicular helper cells during immunity and tolerance
    • Linterman, M. A. & Vinuesa, C. G. T follicular helper cells during immunity and tolerance. Prog. Mol. Biol. Transl. Sci. 92, 207-248 (2010).
    • (2010) Prog. Mol. Biol. Transl. Sci , vol.92 , pp. 207-248
    • Linterman, M.A.1    Vinuesa, C.G.2
  • 16
    • 29144519767 scopus 로고    scopus 로고
    • IL-21 induces differentiation of human naive and memory B cells into antibody-secreting plasma cells
    • Ettinger, R. et al. IL-21 induces differentiation of human naive and memory B cells into antibody-secreting plasma cells. J. Immunol. 175, 7867-7879 (2005).
    • (2005) J. Immunol , vol.175 , pp. 7867-7879
    • Ettinger, R.1
  • 17
    • 6344269331 scopus 로고    scopus 로고
    • Regulation of B cell differentiation and plasma cell generation by IL-21, a novel inducer of Blimp-1 and Bcl-6
    • Ozaki, K. et al. Regulation of B cell differentiation and plasma cell generation by IL-21, a novel inducer of Blimp-1 and Bcl-6. J. Immunol. 173, 5361-5371 (2004).
    • (2004) J. Immunol , vol.173 , pp. 5361-5371
    • Ozaki, K.1
  • 18
    • 0037159687 scopus 로고    scopus 로고
    • A critical role for IL-21 in regulating immunoglobulin production
    • Ozaki, K. et al. A critical role for IL-21 in regulating immunoglobulin production. Science 298, 1630-1634 (2002).
    • (2002) Science , vol.298 , pp. 1630-1634
    • Ozaki, K.1
  • 19
    • 64849083153 scopus 로고    scopus 로고
    • IL-21 mediates suppressive effects via its induction of IL-10
    • Spolski, R., Kim, H. P., Zhu, W., Levy, D. E. & Leonard, W. J. IL-21 mediates suppressive effects via its induction of IL-10. J. Immunol. 182, 2859-2867 (2009).
    • (2009) J. Immunol , vol.182 , pp. 2859-2867
    • Spolski, R.1    Kim, H.P.2    Zhu, W.3    Levy, D.E.4    Leonard, W.J.5
  • 20
    • 69249083836 scopus 로고    scopus 로고
    • Cutting edge: IL-27 induces the transcription factor c-Maf, cytokine IL-21, and the costimulatory receptor ICOS that coordinately act together to promote differentiation of IL-10-producing Tr1 cells
    • Pot, C. et al. Cutting edge: IL-27 induces the transcription factor c-Maf, cytokine IL-21, and the costimulatory receptor ICOS that coordinately act together to promote differentiation of IL-10-producing Tr1 cells. J. Immunol. 183, 797-801 (2009).
    • (2009) J. Immunol , vol.183 , pp. 797-801
    • Pot, C.1
  • 21
    • 0038523790 scopus 로고    scopus 로고
    • Myelin oligodendrocyte glycoprotein-specific T cell receptor transgenic mice develop spontaneous autoimmune optic neuritis
    • Bettelli, E. et al. Myelin oligodendrocyte glycoprotein-specific T cell receptor transgenic mice develop spontaneous autoimmune optic neuritis. J. Exp. Med. 197, 1073-1081 (2003).
    • (2003) J. Exp. Med , vol.197 , pp. 1073-1081
    • Bettelli, E.1
  • 22
    • 33646577466 scopus 로고    scopus 로고
    • Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
    • Bettelli, E. et al. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 441, 235-238 (2006).
    • (2006) Nature , vol.441 , pp. 235-238
    • Bettelli, E.1
  • 23
    • 77956944349 scopus 로고    scopus 로고
    • Regulation of the IL-21 gene by the NF-kB transcription factor c-Rel
    • Chen, G. et al. Regulation of the IL-21 gene by the NF-kB transcription factor c-Rel. J. Immunol. 185, 2350-2359 (2010).
    • (2010) J. Immunol , vol.185 , pp. 2350-2359
    • Chen, G.1
  • 24
    • 79960728714 scopus 로고    scopus 로고
    • Amplified B lymphocyte CD40 signaling drives regulatory B10 cell expansion in mice
    • Poe, J. C. et al. Amplified B lymphocyte CD40 signaling drives regulatory B10 cell expansion in mice. PLoS ONE 6, e22464 (2011).
    • (2011) PLoS ONE , vol.6
    • Poe, J.C.1
  • 25
    • 80052643363 scopus 로고    scopus 로고
    • In-vitro derived germinal centre B cells differentially generate memory B or plasma cells in vivo
    • Nojima, T. et al. In-vitro derived germinal centre B cells differentially generate memory B or plasma cells in vivo. Nature Comm. 2, 465 (2011).
    • (2011) Nature Comm , vol.2 , pp. 465
    • Nojima, T.1
  • 26
    • 0023729241 scopus 로고
    • Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice
    • Goodnow, C. C. et al. Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice. Nature 334, 676-682 (1988).
    • (1988) Nature , vol.334 , pp. 676-682
    • Goodnow, C.C.1
  • 27
    • 46749156754 scopus 로고    scopus 로고
    • Cutting edge: IL-21 is not essential for Th17 differentiation or experimental autoimmune encephalomyelitis
    • Coquet, J. M., Chakravarti, S., Smyth, M. J. & Godfrey, D. I. Cutting edge: IL-21 is not essential for Th17 differentiation or experimental autoimmune encephalomyelitis. J. Immunol. 180, 7097-7101 (2008).
    • (2008) J. Immunol , vol.180 , pp. 7097-7101
    • Coquet, J.M.1    Chakravarti, S.2    Smyth, M.J.3    Godfrey, D.I.4
  • 28
    • 84860328975 scopus 로고    scopus 로고
    • Activation ofCD41 Foxp31 regulatory T cells proceeds normally in the absence of B cells during EAE
    • Hoehlig, K. et al. Activation ofCD41 Foxp31 regulatory T cells proceeds normally in the absence of B cells during EAE. Eur. J. Immunol. 42, 1164-1173 (2012).
    • (2012) Eur. J. Immunol , vol.42 , pp. 1164-1173
    • Hoehlig, K.1
  • 29
    • 34547699396 scopus 로고    scopus 로고
    • Type II monocytes modulate T cell-mediated central nervous system autoimmune disease
    • Weber, M. S. et al. Type II monocytes modulate T cell-mediated central nervous system autoimmune disease. Nature Med. 13, 935-943 (2007).
    • (2007) Nature Med , vol.13 , pp. 935-943
    • Weber, M.S.1
  • 30
    • 79952198828 scopus 로고    scopus 로고
    • Identifying regulatoryBcells (B10cells) that produce IL-10
    • Matsushita, T.&Tedder, T. F. Identifying regulatoryBcells (B10cells) that produce IL-10. Methods Mol. Biol. 677, 99-111 (2011).
    • (2011) Methods Mol. Biol , vol.677 , pp. 99-111
    • Matsushita, T.1    Tedder, T.F.2
  • 31
    • 0027521572 scopus 로고
    • Interleukin-10-deficient mice develop chronic enterocolitis
    • Kühn, R., Lohler, J., Rennick, D., Rajewsky, K.& Muller, W. Interleukin-10-deficient mice develop chronic enterocolitis. Cell 75, 263-274 (1993).
    • (1993) Cell , vol.75 , pp. 263-274
    • Kühn, R.1    Lohler, J.2    Rennick, D.3    Rajewsky, K.4    Muller, W.5
  • 32
    • 0027211875 scopus 로고
    • Mice lacking major histocompatibility complex class i and class II molecules
    • Grusby, M. J. et al. Mice lacking major histocompatibility complex class I and class II molecules. Proc. Natl Acad. Sci. USA 90, 3913-3917 (1993).
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 3913-3917
    • Grusby, M.J.1
  • 33
    • 0030588569 scopus 로고    scopus 로고
    • CD19 regulates B lymphocyte signaling thresholds critical for the development of B-1 lineage cells and autoimmunity
    • Sato, S., Ono, N., Steeber, D. A., Pisetsky, D. S. & Tedder, T. F. CD19 regulates B lymphocyte signaling thresholds critical for the development of B-1 lineage cells and autoimmunity. J. Immunol. 157, 4371-4378 (1996).
    • (1996) J. Immunol , vol.157 , pp. 4371-4378
    • Sato, S.1    Ono, N.2    Steeber, D.A.3    Pisetsky, D.S.4    Tedder, T.F.5
  • 34
    • 0031570122 scopus 로고    scopus 로고
    • CD19 expression levels regulate B lymphocyte development: Human CD19 restores normal function in mice lacking endogenous CD19
    • Sato, S., Steeber, D. A., Jansen, P. J. & Tedder, T. F. CD19 expression levels regulate B lymphocyte development: human CD19 restores normal function in mice lacking endogenous CD19. J. Immunol. 158, 4662-4669 (1997).
    • (1997) J. Immunol , vol.158 , pp. 4662-4669
    • Sato, S.1    Steeber, D.A.2    Jansen, P.J.3    Tedder, T.F.4
  • 35
    • 0028355752 scopus 로고
    • Tissue-specific expression of the humanCD19gene in transgenic mice inhibits antigen-independent B lymphocyte development
    • Zhou, L.-J. et al. Tissue-specific expression of the humanCD19gene in transgenic mice inhibits antigen-independent B lymphocyte development. Mol. Cell. Biol. 14, 3884-3894 (1994).
    • (1994) Mol. Cell. Biol , vol.14 , pp. 3884-3894
    • Zhou, L.-J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.