Two discreet subsets of CD8 T cells modulate PLP 91-110 induced experimental autoimmune encephalomyelitis in HLA-DR3 transgenic mice

Journal of Autoimmunity

Volumn 38, Issue 4, 2012, Pages 344-353

  Mangalam, Ashutosh K ^a   Luckey, David ^a   Giri, Shailendra ^b   Smart, Michele ^a   Pease, Larry R ^a   Rodriguez, Moses ^a,b   David, Chella S ^a  

^a MAYO GRADUATE SCHOOL   (United States)

^b MAYO CLINIC   (United States)

Author keywords

CD8 regulatory T cells; Cytokine; Demyelination; Experimental autoimmune encephalomyelitis; HLA class II transgenic mice; Multiple sclerosis

Indexed keywords

CD8 ANTIGEN; GAMMA INTERFERON; HLA DR3 ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 2 RECEPTOR BETA; INTERLEUKIN 4; INTERLEUKIN 6; SYNTHETIC PEPTIDE; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

ADOPTIVE TRANSFER; ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; ANTIGEN PRESENTING CELL; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOTOXICITY; DEMYELINATION; DISEASE SEVERITY; GLIA CELL; IMMUNIZATION; IMMUNOMODULATION; IMMUNOREGULATION; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE FUNCTION; LYMPHOCYTE TRANSFER; MOUSE; MULTIPLE SCLEROSIS; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; SPINAL CORD; T LYMPHOCYTE SUBPOPULATION; TRANSGENIC MOUSE;

ADOPTIVE TRANSFER; ANIMALS; ANTIGEN-PRESENTING CELLS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL COMMUNICATION; CENTRAL NERVOUS SYSTEM; CYTOKINES; CYTOTOXICITY, IMMUNOLOGIC; DEMYELINATING DISEASES; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; HLA-DR3 ANTIGEN; INTERLEUKIN-2 RECEPTOR BETA SUBUNIT; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MYELIN PROTEOLIPID PROTEIN; NEUROGLIA;

EID: 84861193712     PISSN: 08968411     EISSN: 10959157     Source Type: Journal    
DOI: 10.1016/j.jaut.2012.02.004     Document Type: Article

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