Critical role of antigen-specific antibody in experimental autoimmune encephalomyelitis induced by recombinant myelin oligodendrocyte glycoprotein

European Journal of Immunology

Volumn 32, Issue 7, 2002, Pages 1905-1913

  Lyons, Jeri Anne ^a   Ramsbottom, Michael J ^a   Cross, Anne H ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Antibody; B cell; Experimental autoimmune encephalomyelitis; Myelin oligodendrocyte glycoprotein

Indexed keywords

ANTIBODY; ANTIGEN; LIPOPOLYSACCHARIDE; LYSOZYME; MYELIN BASIC PROTEIN; MYELIN OLIGODENDROCYTE GLYCOPROTEIN;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN SPECIFICITY; ARTICLE; B LYMPHOCYTE; B LYMPHOCYTE ACTIVATION; CELL ISOLATION; CENTRAL NERVOUS SYSTEM DISEASE; CLINICAL FEATURE; CONTROLLED STUDY; DEMYELINATION; HISTOPATHOLOGY; IMMUNIZATION; LYMPHOCYTE TRANSFER; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; WILD TYPE;

ADOPTIVE TRANSFER; AMINO ACID SEQUENCE; ANIMALS; AUTOANTIBODIES; AUTOANTIGENS; B-LYMPHOCYTES; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; GLYCOPROTEINS; HUMANS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOLECULAR SEQUENCE DATA; MYELIN-ASSOCIATED GLYCOPROTEIN; PEPTIDE FRAGMENTS; SPINAL CORD;

EID: 0036312179     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200207)32:7<1905::AID-IMMU1905>3.0.CO;2-L     Document Type: Article

References (28)

1. Experimental autoimmune encephalomyelitis induction in genetically B cell-deficient mice
2. B cell-deficient mice develop experimental allergic encephalomyelitis with demyelination after myelin oligodendrocyte glycoprotein sensitization
3. B cells are critical to induction of experimental allergic encephalomyelitis by protein but not by a short encephalitogenic peptide
4. Relapsing and remitting experimental autoimmune encephalomyelitis in B cell deficient mice
5. Increased CD80 sup + B cells in active multiple sclerosis and reversal by interferon beta-1b therapy
6. T cell antigen CD28 mediates adhesion with B cells by interacting with the activation antigen B7/BB-1
7. Resting B lymphocytes as APC for Naive T Lymphocytes: Dependence on CD40 Ligand/CD40
8. Signal thresholds and modular synergy during expression of costimulatory molecules in B lymphocytes
9. TNF is a potent anti-inflammatory cytokine in autoimmune-mediated demyelination
10. Macrophages, lymphocytes, and plasma cells in the perivascular compartment in chronic multiple sclerosis
11. Multiple Sclerosis Chapter 18
12. Identification of autoantibodies associated with myelin damage in multiple sclerosis
13. Immunogold localization and analysis of IgG during immune-mediated demyelination
14. A monoclonal antibody against a myelin oligodendrocyte glycoprotein induces relapses and demyelination in central nervous system autoimmune disease
15. Antibody facilitation of multiple sclerosis-like lesions in a nonhuman primate
16. Intact B cell activity is essential for complete expression of experimental allergic encephalomyelitis in Lewis rats
17. Immunoglobulin deficient rats as donors and recipients of effector cells of allergic encephalomyelitis
18. Synergy between encephalitogenic T cells and myelin basic protein-specific antibodies in the induction of experimental autoimmune encephalomyelitis
19. Evidence for an underlying CD4 helper and CD8 T cell defect in B cell-deficient mice: Failure to clear persistent virus infection after adoptive immunotherapy with virus-specific memory cells from μMT/μMT mice
20. Antigen-primed T cells from B cell-deficient JHD mice fail to provide B cell help
21. Determinant spreading associated with demyelination in a nonhuman primate model of multiple sclerosis
22. A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin m chain gene
23. Induction of EAE in mice with recombinant human MOG, and treatment of EAE with MOG peptide
24. Aminoguanidine, an inhibitor of inducible nitric oxide synthase, ameliorates experimental autoimmune encephalomyelitis in SJL mice
25. Nerve growth factor is an autocrine survival factor for memory B lymphocytes
26. B cell stimulatory factor 1 activates resting B cells
27. B cell growth factor (B cell Growth factor I or B cell stimulating factor, provisional I) is a differentiation factor for resting B cells and may not induce cell growth
28. Assays for B cell Function