메뉴 건너뛰기




Volumn 8, Issue 5, 2013, Pages 1106-1113

Fingolimod modulates peripheral effector and regulatory T cells in MS patients

Author keywords

Fingolimod; IFN ; IL 17; Multiple sclerosis; S1P; T cells

Indexed keywords

CD161 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; CHEMOKINE RECEPTOR CCR6; FINGOLIMOD; GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 7 RECEPTOR;

EID: 84891371436     PISSN: 15571890     EISSN: 15571904     Source Type: Journal    
DOI: 10.1007/s11481-013-9465-5     Document Type: Article
Times cited : (67)

References (27)
  • 2
    • 84866749073 scopus 로고    scopus 로고
    • Defining the human T helper 17 cell phenotype
    • 22682163 10.1016/j.it.2012.05.004 1:CAS:528:DC%2BC38Xot12js7Y%3D
    • Annunziato F, Cosmi L, Liotta F, Maggi E, Romagnani S (2012) Defining the human T helper 17 cell phenotype. Trends Immunol 33:505-512
    • (2012) Trends Immunol , vol.33 , pp. 505-512
    • Annunziato, F.1    Cosmi, L.2    Liotta, F.3    Maggi, E.4    Romagnani, S.5
  • 4
    • 77953123877 scopus 로고    scopus 로고
    • Haplotype 4 of the multiple sclerosis-associated interleukin-7 receptor alpha gene influences the frequency of recent thymic emigrants
    • 20072142 10.1038/gene.2009.106 1:CAS:528:DC%2BC3cXmslKqu7s%3D
    • Broux B, Hellings N, Venken K, Rummens JL, Hensen K, Van Wijmeersch B, Stinissen P (2010) Haplotype 4 of the multiple sclerosis-associated interleukin-7 receptor alpha gene influences the frequency of recent thymic emigrants. Genes Immun 11:326-333
    • (2010) Genes Immun , vol.11 , pp. 326-333
    • Broux, B.1    Hellings, N.2    Venken, K.3    Rummens, J.L.4    Hensen, K.5    Van Wijmeersch, B.6    Stinissen, P.7
  • 5
    • 72649089874 scopus 로고    scopus 로고
    • Phenotypical and functional characterization of T helper 17 cells in multiple sclerosis
    • 19933767 10.1093/brain/awp289
    • Brucklacher-Waldert V, Stuerner K, Kolster M, Wolthausen J, Tolosa E (2009) Phenotypical and functional characterization of T helper 17 cells in multiple sclerosis. Brain 132:3329-3341
    • (2009) Brain , vol.132 , pp. 3329-3341
    • Brucklacher-Waldert, V.1    Stuerner, K.2    Kolster, M.3    Wolthausen, J.4    Tolosa, E.5
  • 7
    • 54149084585 scopus 로고    scopus 로고
    • Multiple sclerosis
    • 18970977 10.1016/S0140-6736(08)61620-7 1:CAS:528:DC%2BD1cXht12gtLvN
    • Compston A, Coles A (2008) Multiple sclerosis. Lancet 372:1502-1517
    • (2008) Lancet , vol.372 , pp. 1502-1517
    • Compston, A.1    Coles, A.2
  • 10
    • 84859385704 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate and lymphocyte egress from lymphoid organs
    • 22149932 10.1146/annurev-immunol-020711-075011 1:CAS:528: DC%2BC38XmsVKmtLY%3D
    • Cyster JG, Schwab SR (2012) Sphingosine-1-phosphate and lymphocyte egress from lymphoid organs. Annu Rev Immunol 30:69-94
    • (2012) Annu Rev Immunol , vol.30 , pp. 69-94
    • Cyster, J.G.1    Schwab, S.R.2
  • 12
    • 70149122373 scopus 로고    scopus 로고
    • Pathogenic CD8(+) T cells in multiple sclerosis
    • 19743458 10.1002/ana.21744 1:CAS:528:DC%2BD1MXht1ansrbJ
    • Friese MA, Fugger L (2009) Pathogenic CD8(+) T cells in multiple sclerosis. Ann Neurol 66:132-141
    • (2009) Ann Neurol , vol.66 , pp. 132-141
    • Friese, M.A.1    Fugger, L.2
  • 13
    • 67349216357 scopus 로고    scopus 로고
    • Autoimmune T cell responses in the central nervous system
    • 19444307 10.1038/nri2550 1:CAS:528:DC%2BD1MXlvFShs7c%3D 2813731
    • Goverman J (2009) Autoimmune T cell responses in the central nervous system. Nat Rev Immunol 9:393-407
    • (2009) Nat Rev Immunol , vol.9 , pp. 393-407
    • Goverman, J.1
  • 16
    • 70350052626 scopus 로고    scopus 로고
    • Preferential recruitment of interferon-gamma-expressing TH17 cells in multiple sclerosis
    • 19810097 10.1002/ana.21748 1:CAS:528:DC%2BD1MXhtlCgtL7N
    • Kebir H, Ifergan I, Alvarez JI, Bernard M, Poirier J, Arbour N, Duquette P, Prat A (2009) Preferential recruitment of interferon-gamma-expressing TH17 cells in multiple sclerosis. Ann Neurol 66:390-402
    • (2009) Ann Neurol , vol.66 , pp. 390-402
    • Kebir, H.1    Ifergan, I.2    Alvarez, J.I.3    Bernard, M.4    Poirier, J.5    Arbour, N.6    Duquette, P.7    Prat, A.8
  • 17
    • 61449184521 scopus 로고    scopus 로고
    • Cutting edge: Phenotypic characterization and differentiation of human CD8+ T cells producing IL-17
    • 19201830 10.4049/jimmunol.0801347 1:CAS:528:DC%2BD1MXhsFKktL4%3D
    • Kondo T, Takata H, Matsuki F, Takiguchi M (2009) Cutting edge: Phenotypic characterization and differentiation of human CD8+ T cells producing IL-17. J Immunol 182:1794-1798
    • (2009) J Immunol , vol.182 , pp. 1794-1798
    • Kondo, T.1    Takata, H.2    Matsuki, F.3    Takiguchi, M.4
  • 21
    • 77955358808 scopus 로고    scopus 로고
    • Th17 central memory T cells are reduced by FTY720 in patients with multiple sclerosis
    • 20592255 10.1212/WNL.0b013e3181ebdd64 1:CAS:528:DC%2BC3cXpslWqsL8%3D
    • Mehling M, Lindberg R, Raulf F, Kuhle J, Hess C, Kappos L, Brinkmann V (2010) Th17 central memory T cells are reduced by FTY720 in patients with multiple sclerosis. Neurology 75:403-410
    • (2010) Neurology , vol.75 , pp. 403-410
    • Mehling, M.1    Lindberg, R.2    Raulf, F.3    Kuhle, J.4    Hess, C.5    Kappos, L.6    Brinkmann, V.7
  • 25
    • 38749143286 scopus 로고    scopus 로고
    • Interleukin-17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis
    • 18156204 10.2353/ajpath.2008.070690 1:CAS:528:DC%2BD1cXhslOmur0%3D 2189615
    • Tzartos JS, Friese MA, Craner MJ, Palace J, Newcombe J, Esiri MM, Fugger L (2008) Interleukin-17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis. Am J Pathol 172:146-155
    • (2008) Am J Pathol , vol.172 , pp. 146-155
    • Tzartos, J.S.1    Friese, M.A.2    Craner, M.J.3    Palace, J.4    Newcombe, J.5    Esiri, M.M.6    Fugger, L.7
  • 26
    • 1842732224 scopus 로고    scopus 로고
    • Loss of functional suppression by CD4+ CD25+ regulatory T cells in patients with multiple sclerosis
    • 15067033 10.1084/jem.20031579 1:CAS:528:DC%2BD2cXjtVejurw%3D 2211881
    • Viglietta V, Baecher-Allan C, Weiner HL, Hafler DA (2004) Loss of functional suppression by CD4+ CD25+ regulatory T cells in patients with multiple sclerosis. J Exp Med 199:971-979
    • (2004) J Exp Med , vol.199 , pp. 971-979
    • Viglietta, V.1    Baecher-Allan, C.2    Weiner, H.L.3    Hafler, D.A.4
  • 27
    • 74049164847 scopus 로고    scopus 로고
    • Regulatory T cells exert checks and balances on self tolerance and autoimmunity
    • 20016504 10.1038/ni.1818 1:CAS:528:DC%2BD1MXhsFKnsbrO
    • Wing K, Sakaguchi S (2010) Regulatory T cells exert checks and balances on self tolerance and autoimmunity. Nat Immunol 11:7-13
    • (2010) Nat Immunol , vol.11 , pp. 7-13
    • Wing, K.1    Sakaguchi, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.