Drug delivery, cell-based therapies, and tissue engineering approaches for spinal cord injury

Journal of Controlled Release

Volumn 219, Issue , 2015, Pages 141-154

  Kabu, Shushi ^a   Gao, Yue ^a   Kwon, Brian K ^b   Labhasetwar, Vinod ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

CNS injury; Drug therapy; Gene therapy; Growth factors; Inflammation; Polymers; Scaffold

Indexed keywords

CONTROLLED DRUG DELIVERY; DRUG THERAPY; GENE THERAPY; PATIENT REHABILITATION; POLYMERS; SCAFFOLDS; SECONDARY RECOVERY; TARGETED DRUG DELIVERY; TISSUE; TISSUE ENGINEERING;

CELL BASED THERAPIES; CNS INJURIES; DOSE LIMITING TOXICITY; GROWTH FACTOR; INFLAMMATION; SPINAL CORD INJURIES (SCI); THERAPEUTIC INTERVENTION; THERAPEUTIC STRATEGY;

CELL ENGINEERING;

CATALASE; ERYTHROPOIETIN; FAMPRIDINE; IRON; MINOCYCLINE; NANOFIBER; NANOPARTICLE; NOGO A ANTIBODY; RHO KINASE INHIBITOR; RILUZOLE; SELF ASSEMBLING NANOFIBER; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; ASTROCYTE; AXONAL GROWTH; BONE MARROW STROMA CELL; CELL HYPOXIA; CELL THERAPY; DRUG DELIVERY SYSTEM; DRUG THERAPY; EPITHELIUM CELL; GENE THERAPY; HUMAN; HYDROGEL; IMMUNOTHERAPY; MACROPHAGE; MESENCHYMAL STEM CELL; MUCOSA CELL; MULTICENTER STUDY (TOPIC); NERVE CELL GROWTH; NERVE CELL NECROSIS; NERVE FIBER; NEURAL STEM CELL; NONHUMAN; OLFACTORY ENSHEATHING CELL; OLFACTORY MUCOSA CELL; OLIGODENDROCYTE STEM CELL; OLIGODENDROGLIA; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PHASE 1 CLINICAL TRIAL (TOPIC); PHASE 2 CLINICAL TRIAL (TOPIC); PHASE 3 CLINICAL TRIAL (TOPIC); PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); REGENERATIVE MEDICINE; SCHWANN CELL; SOMATIC CELL; SPINAL CORD INJURY; STEM CELL; TISSUE ENGINEERING; ANIMAL; BIOLOGICAL THERAPY; SPINAL CORD INJURIES;

ANIMALS; CELL- AND TISSUE-BASED THERAPY; DRUG DELIVERY SYSTEMS; GENETIC THERAPY; HUMANS; SPINAL CORD INJURIES; TISSUE ENGINEERING;

EID: 84947494370     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2015.08.060     Document Type: Review

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