Combination of engineered Schwann cell grafts to secrete neurotrophin and chondroitinase promotes axonal regeneration and locomotion after spinal cord injury

Journal of Neuroscience

Volumn 34, Issue 5, 2014, Pages 1838-1855

  Kanno, Haruo ^a,c   Pressman, Yelena ^a   Moody, Alison ^a   Berg, Randall ^a   Muir, Elizabeth M ^b   Rogers, John H ^b   Ozawa, Hiroshi ^c   Itoi, Eiji ^c   Pearse, Damien D ^a   Bunge, Mary Bartlett ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Cell transplantation; Chondroitinase; Glial scar; Schwann cell; Spinal cord injury

Indexed keywords

CHONDROITIN ABC LYASE; N ACETYLGALACTOSAMINE 4 SULFATASE; NEUROTROPHIN; PROTEOCHONDROITIN SULFATE; SEROTONIN;

ALLODYNIA; ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTOSIS; CATWALK GAIT ANALYSIS TEST; CELL MIGRATION; CONTROLLED STUDY; CONTUSION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENETIC TRANSDUCTION; IMMUNOHISTOCHEMISTRY; LOCOMOTION; NERVE FIBER REGENERATION; NONHUMAN; OPEN FIELD TEST; PRIORITY JOURNAL; RAT; SCHWANN CELL; SPINAL CORD INJURY;

CELL TRANSPLANTATION; CHONDROITINASE; GLIAL SCAR; SCHWANN CELL; SPINAL CORD INJURY;

ANIMALS; AXONS; BIOENGINEERING; CHONDROITIN ABC LYASE; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HYPERALGESIA; LOCOMOTION; LUMINESCENT PROTEINS; MICE; NERVE GROWTH FACTORS; NERVE REGENERATION; PAIN THRESHOLD; RATS; RATS, INBRED F344; SCHWANN CELLS; SEROTONIN; SPINAL CORD INJURIES;

EID: 84893154288     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2661-13.2014     Document Type: Article

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