Lecithinized superoxide dismutase improves outcomes and attenuates focal cerebral ischemic injury via antiapoptotic mechanisms in rats

Stroke

Volumn 38, Issue 3, 2007, Pages 1057-1062

  Tsubokawa, Tamiji ^a   Jadhav, Vikram ^a   Solaroglu, Ihsan ^a   Shiokawa, Yoshiaki ^b   Konishi, Yoshifumi ^b   Zhang, John H ^a,c  

^a LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b KYORIN UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c LOMA LINDA UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Cerebral ischemia; Lecithinized superoxide dismutase; Neuronal apoptosis; Oxidative stress

Indexed keywords

CASPASE 3; CYTOCHROME C; MALONALDEHYDE; NEUROPROTECTIVE AGENT; PHOSPHATIDYLCHOLINE SUPEROXIDE DISMUTASE; PROTEIN BCL 2; UNCLASSIFIED DRUG; LECITHINIZED SUPEROXIDE DISMUTASE; PHOSPHATIDYLCHOLINE; RECOMBINANT PROTEIN; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; BIOASSAY; BRAIN INFARCTION; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CONTROLLED STUDY; DRUG DOSE INCREASE; DRUG EFFECT; DRUG EFFICACY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPHARMACOLOGY; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SCORING SYSTEM; SINGLE DRUG DOSE; WESTERN BLOTTING; ANIMAL; COMPARATIVE STUDY; METABOLISM; PATHOLOGY; PHYSIOLOGY; SPRAGUE DAWLEY RAT; TREATMENT OUTCOME;

ANIMALS; APOPTOSIS; BRAIN ISCHEMIA; MALE; OXIDATIVE STRESS; PHOSPHATIDYLCHOLINES; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS; SUPEROXIDE DISMUTASE; TREATMENT OUTCOME;

EID: 33947539355     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.STR.0000257978.70312.1d     Document Type: Article

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