-
1
-
-
70449473470
-
A novel inducible tyrosine kinase receptor to regulate signal transduction and neurite outgrowth
-
Alfa R.W., Tuszynski M.H., Blesch A. A novel inducible tyrosine kinase receptor to regulate signal transduction and neurite outgrowth. J. Neurosci. Res. 2009, 87:2624-2631.
-
(2009)
J. Neurosci. Res.
, vol.87
, pp. 2624-2631
-
-
Alfa, R.W.1
Tuszynski, M.H.2
Blesch, A.3
-
2
-
-
69449094846
-
Chemotropic guidance facilitates axonal regeneration and synapse formation after spinal cord injury
-
Alto L.T., Havton L.A., Conner J.M., Hollis Ii E.R., Blesch A., Tuszynski M.H. Chemotropic guidance facilitates axonal regeneration and synapse formation after spinal cord injury. Nat. Neurosci. 2009, 12:1106-1113.
-
(2009)
Nat. Neurosci.
, vol.12
, pp. 1106-1113
-
-
Alto, L.T.1
Havton, L.A.2
Conner, J.M.3
Hollis Ii, E.R.4
Blesch, A.5
Tuszynski, M.H.6
-
3
-
-
5044220530
-
Bone marrow transplants provide tissue protection and directional guidance for axons after contusive spinal cord injury in rats
-
Ankeny D.P., McTigue D.M., Jakeman L.B. Bone marrow transplants provide tissue protection and directional guidance for axons after contusive spinal cord injury in rats. Exp. Neurol. 2004, 190:17-31.
-
(2004)
Exp. Neurol.
, vol.190
, pp. 17-31
-
-
Ankeny, D.P.1
McTigue, D.M.2
Jakeman, L.B.3
-
4
-
-
85047689522
-
Lentivector-mediated SMN replacement in a mouse model of spinal muscular atrophy
-
Azzouz M., Le T., Ralph G.S., Walmsley L., Monani U.R., Lee D.C., Wilkes F., Mitrophanous K.A., Kingsman S.M., Burghes A.H., Mazarakis N.D. Lentivector-mediated SMN replacement in a mouse model of spinal muscular atrophy. J. Clin. Invest. 2004, 114:1726-1731.
-
(2004)
J. Clin. Invest.
, vol.114
, pp. 1726-1731
-
-
Azzouz, M.1
Le, T.2
Ralph, G.S.3
Walmsley, L.4
Monani, U.R.5
Lee, D.C.6
Wilkes, F.7
Mitrophanous, K.A.8
Kingsman, S.M.9
Burghes, A.H.10
Mazarakis, N.D.11
-
5
-
-
33645967159
-
Spontaneous locomotor recovery in spinal cord injured rats is accompanied by anatomical plasticity of reticulospinal fibers
-
Ballermann M., Fouad K. Spontaneous locomotor recovery in spinal cord injured rats is accompanied by anatomical plasticity of reticulospinal fibers. Eur. J. Neurosci. 2006, 23:1988-1996.
-
(2006)
Eur. J. Neurosci.
, vol.23
, pp. 1988-1996
-
-
Ballermann, M.1
Fouad, K.2
-
6
-
-
0035122596
-
Neurotrophins BDNF and NT-3 promote axonal re-entry into the distal host spinal cord through Schwann cell-seeded mini-channels
-
Bamber N.I., Li H., Lu X., Oudega M., Aebischer P., Xu X.M. Neurotrophins BDNF and NT-3 promote axonal re-entry into the distal host spinal cord through Schwann cell-seeded mini-channels. Eur. J. Neurosci. 2001, 13:257-268.
-
(2001)
Eur. J. Neurosci.
, vol.13
, pp. 257-268
-
-
Bamber, N.I.1
Li, H.2
Lu, X.3
Oudega, M.4
Aebischer, P.5
Xu, X.M.6
-
7
-
-
23044477800
-
Ephrin-B3 is a myelin-based inhibitor of neurite outgrowth
-
Benson M.D., Romero M.I., Lush M.E., Lu Q.R., Henkemeyer M., Parada L.F. Ephrin-B3 is a myelin-based inhibitor of neurite outgrowth. Proc. Natl Acad. Sci. USA 2005, 102:10694-10699.
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 10694-10699
-
-
Benson, M.D.1
Romero, M.I.2
Lush, M.E.3
Lu, Q.R.4
Henkemeyer, M.5
Parada, L.F.6
-
8
-
-
0036264280
-
Targeting the host inflammatory response in traumatic spinal cord injury
-
Bethea J.R., Dietrich W.D. Targeting the host inflammatory response in traumatic spinal cord injury. Curr. Opin. Neurol. 2002, 15:355-360.
-
(2002)
Curr. Opin. Neurol.
, vol.15
, pp. 355-360
-
-
Bethea, J.R.1
Dietrich, W.D.2
-
9
-
-
77950339970
-
High content screening of cortical neurons identifies novel regulators of axon growth
-
Blackmore M.G., Moore D.L., Smith R.P., Goldberg J.L., Bixby J.L., Lemmon V.P. High content screening of cortical neurons identifies novel regulators of axon growth. Mol. Cell. Neurosci. 2010, 44:43-54.
-
(2010)
Mol. Cell. Neurosci.
, vol.44
, pp. 43-54
-
-
Blackmore, M.G.1
Moore, D.L.2
Smith, R.P.3
Goldberg, J.L.4
Bixby, J.L.5
Lemmon, V.P.6
-
10
-
-
0242497104
-
Cellular GDNF delivery promotes growth of motor and dorsal column sensory axons after partial and complete spinal cord transection and induces remyelination
-
Blesch A., Tuszynski M.H. Cellular GDNF delivery promotes growth of motor and dorsal column sensory axons after partial and complete spinal cord transection and induces remyelination. J. Comp. Neurol. 2003, 467:403-417.
-
(2003)
J. Comp. Neurol.
, vol.467
, pp. 403-417
-
-
Blesch, A.1
Tuszynski, M.H.2
-
11
-
-
34848866015
-
Transient growth factor delivery sustains regenerated axons after spinal cord injury
-
Blesch A., Tuszynski M.H. Transient growth factor delivery sustains regenerated axons after spinal cord injury. J. Neurosci. 2007, 27:10535-10545.
-
(2007)
J. Neurosci.
, vol.27
, pp. 10535-10545
-
-
Blesch, A.1
Tuszynski, M.H.2
-
12
-
-
0033135389
-
Leukemia inhibitory factor augments neurotrophin expression and corticospinal axon growth after adult CNS injury
-
Blesch A., Uy H.S., Grill R.J., Cheng J.G., Patterson P.H., Tuszynski M.H. Leukemia inhibitory factor augments neurotrophin expression and corticospinal axon growth after adult CNS injury. J. Neurosci. 1999, 19:3556-3566.
-
(1999)
J. Neurosci.
, vol.19
, pp. 3556-3566
-
-
Blesch, A.1
Uy, H.S.2
Grill, R.J.3
Cheng, J.G.4
Patterson, P.H.5
Tuszynski, M.H.6
-
13
-
-
5644264890
-
Axonal responses to cellularly delivered NT-4/5 after spinal cord injury
-
Blesch A., Yang H., Weidner N., Hoang A., Otero D. Axonal responses to cellularly delivered NT-4/5 after spinal cord injury. Mol. Cell. Neurosci. 2004, 27:190-201.
-
(2004)
Mol. Cell. Neurosci.
, vol.27
, pp. 190-201
-
-
Blesch, A.1
Yang, H.2
Weidner, N.3
Hoang, A.4
Otero, D.5
-
14
-
-
72249104303
-
Adeno-associated viral vector (AAV)-mediated gene transfer in the red nucleus of the adult rat brain: comparative analysis of the transduction properties of seven AAV serotypes and lentiviral vectors
-
Blits B., Derks S., Twisk J., Ehlert E., Prins J., Verhaagen J. Adeno-associated viral vector (AAV)-mediated gene transfer in the red nucleus of the adult rat brain: comparative analysis of the transduction properties of seven AAV serotypes and lentiviral vectors. J. Neurosci. Meth. 2010, 185:257-263.
-
(2010)
J. Neurosci. Meth.
, vol.185
, pp. 257-263
-
-
Blits, B.1
Derks, S.2
Twisk, J.3
Ehlert, E.4
Prins, J.5
Verhaagen, J.6
-
15
-
-
0033942954
-
Intercostal nerve implants transduced with an adenoviral vector encoding neurotrophin-3 promote regrowth of injured rat corticospinal tract fibers and improve hindlimb function
-
Blits B., Dijkhuizen P.A., Boer G.J., Verhaagen J. Intercostal nerve implants transduced with an adenoviral vector encoding neurotrophin-3 promote regrowth of injured rat corticospinal tract fibers and improve hindlimb function. Exp. Neurol. 2000, 164:25-37.
-
(2000)
Exp. Neurol.
, vol.164
, pp. 25-37
-
-
Blits, B.1
Dijkhuizen, P.A.2
Boer, G.J.3
Verhaagen, J.4
-
16
-
-
52649176389
-
Axonal guidance molecules and the failure of axonal regeneration in the adult mammalian spinal cord
-
Bolsover S., Fabes J., Anderson P.N. Axonal guidance molecules and the failure of axonal regeneration in the adult mammalian spinal cord. Restor. Neurol. Neurosci. 2008, 26:117-130.
-
(2008)
Restor. Neurol. Neurosci.
, vol.26
, pp. 117-130
-
-
Bolsover, S.1
Fabes, J.2
Anderson, P.N.3
-
17
-
-
77951565691
-
Promoting directional axon growth from neural progenitors grafted into the injured spinal cord
-
Bonner J.F., Blesch A., Neuhuber B., Fischer I. Promoting directional axon growth from neural progenitors grafted into the injured spinal cord. J. Neurosci. Res. 2010, 88:1182-1192.
-
(2010)
J. Neurosci. Res.
, vol.88
, pp. 1182-1192
-
-
Bonner, J.F.1
Blesch, A.2
Neuhuber, B.3
Fischer, I.4
-
18
-
-
0346218252
-
Adeno-associated viral vector gene expression in the adult rat spinal cord following remote vector delivery
-
Boulis N.M., Noordmans A.J., Song D.K., Imperiale M.J., Rubin A., Leone P., During M., Feldman E.L. Adeno-associated viral vector gene expression in the adult rat spinal cord following remote vector delivery. Neurobiol. Dis. 2003, 14:535-541.
-
(2003)
Neurobiol. Dis.
, vol.14
, pp. 535-541
-
-
Boulis, N.M.1
Noordmans, A.J.2
Song, D.K.3
Imperiale, M.J.4
Rubin, A.5
Leone, P.6
During, M.7
Feldman, E.L.8
-
19
-
-
0032722126
-
NT-3 promotes growth of lesioned adult rat sensory axons ascending in the dorsal columns of the spinal cord
-
Bradbury E.J., Khemani S., Von R., King Priestley J.V., McMahon S.B. NT-3 promotes growth of lesioned adult rat sensory axons ascending in the dorsal columns of the spinal cord. Eur. J. Neurosci. 1999, 11:3873-3883.
-
(1999)
Eur. J. Neurosci.
, vol.11
, pp. 3873-3883
-
-
Bradbury, E.J.1
Khemani, S.2
Von, R.3
King Priestley, J.V.4
McMahon, S.B.5
-
20
-
-
0027504205
-
Recovery of function after spinal cord injury: mechanisms underlying transplant-mediated recovery of function differ after spinal cord injury in newborn and adult rats
-
Bregman B.S., Kunkel-Bagden E., Reier P.J., Dai H.N., McAtee M., Gao D. Recovery of function after spinal cord injury: mechanisms underlying transplant-mediated recovery of function differ after spinal cord injury in newborn and adult rats. Exp. Neurol. 1993, 123:3-16.
-
(1993)
Exp. Neurol.
, vol.123
, pp. 3-16
-
-
Bregman, B.S.1
Kunkel-Bagden, E.2
Reier, P.J.3
Dai, H.N.4
McAtee, M.5
Gao, D.6
-
21
-
-
77954835104
-
Local and remote growth factor effects after primate spinal cord injury
-
Brock J.H., Rosenzweig E.S., Blesch A., Moseanko R., Havton L.A., Edgerton V.R., Tuszynski M.H. Local and remote growth factor effects after primate spinal cord injury. J. Neurosci. 2010, 30:9728-9737.
-
(2010)
J. Neurosci.
, vol.30
, pp. 9728-9737
-
-
Brock, J.H.1
Rosenzweig, E.S.2
Blesch, A.3
Moseanko, R.4
Havton, L.A.5
Edgerton, V.R.6
Tuszynski, M.H.7
-
22
-
-
4344566457
-
Recombinant AAV viral vectors pseudotyped with viral capsids from serotypes 1, 2, and 5 display differential efficiency and cell tropism after delivery to different regions of the central nervous system
-
Burger C., Gorbatyuk O.S., Velardo M.J., Peden C.S., Williams P., Zolotukhin S., Reier P.J., Mandel R.J., Muzyczka N. Recombinant AAV viral vectors pseudotyped with viral capsids from serotypes 1, 2, and 5 display differential efficiency and cell tropism after delivery to different regions of the central nervous system. Mol. Ther. 2004, 10:302-317.
-
(2004)
Mol. Ther.
, vol.10
, pp. 302-317
-
-
Burger, C.1
Gorbatyuk, O.S.2
Velardo, M.J.3
Peden, C.S.4
Williams, P.5
Zolotukhin, S.6
Reier, P.J.7
Mandel, R.J.8
Muzyczka, N.9
-
23
-
-
2342493315
-
Conditioning injury-induced spinal axon regeneration fails in interleukin-6 knock-out mice
-
Cafferty W.B., Gardiner N.J., Das P., Qiu J., McMahon S.B., Thompson S.W. Conditioning injury-induced spinal axon regeneration fails in interleukin-6 knock-out mice. J. Neurosci. 2004, 24:4432-4443.
-
(2004)
J. Neurosci.
, vol.24
, pp. 4432-4443
-
-
Cafferty, W.B.1
Gardiner, N.J.2
Das, P.3
Qiu, J.4
McMahon, S.B.5
Thompson, S.W.6
-
24
-
-
0035399823
-
Neuronal cyclic AMP controls the developmental loss in ability of axons to regenerate
-
Cai D., Qiu J., Cao Z., McAtee M., Bregman B.S., Filbin M.T. Neuronal cyclic AMP controls the developmental loss in ability of axons to regenerate. J. Neurosci. 2001, 21:4731-4739.
-
(2001)
J. Neurosci.
, vol.21
, pp. 4731-4739
-
-
Cai, D.1
Qiu, J.2
Cao, Z.3
McAtee, M.4
Bregman, B.S.5
Filbin, M.T.6
-
25
-
-
1542375991
-
Olfactory ensheathing cells genetically modified to secrete GDNF to promote spinal cord repair
-
Cao L., Liu L., Chen Z.Y., Wang L.M., Ye J.L., Qiu H.Y., Lu C.L., He C. Olfactory ensheathing cells genetically modified to secrete GDNF to promote spinal cord repair. Brain 2004, 127:535-549.
-
(2004)
Brain
, vol.127
, pp. 535-549
-
-
Cao, L.1
Liu, L.2
Chen, Z.Y.3
Wang, L.M.4
Ye, J.L.5
Qiu, H.Y.6
Lu, C.L.7
He, C.8
-
26
-
-
23044446572
-
Functional recovery in traumatic spinal cord injury after transplantation of multineurotrophin-expressing glial-restricted precursor cells
-
Cao Q., Xu X.M., Devries W.H., Enzmann G.U., Ping P., Tsoulfas P., Wood P.M., Bunge M.B., Whittemore S.R. Functional recovery in traumatic spinal cord injury after transplantation of multineurotrophin-expressing glial-restricted precursor cells. J. Neurosci. 2005, 25:6947-6957.
-
(2005)
J. Neurosci.
, vol.25
, pp. 6947-6957
-
-
Cao, Q.1
Xu, X.M.2
Devries, W.H.3
Enzmann, G.U.4
Ping, P.5
Tsoulfas, P.6
Wood, P.M.7
Bunge, M.B.8
Whittemore, S.R.9
-
27
-
-
33744997909
-
The cytokine interleukin-6 is sufficient but not necessary to mimic the peripheral conditioning lesion effect on axonal growth
-
Cao Z., Gao Y., Bryson J.B., Hou J., Chaudhry N., Siddiq M., Martinez J., Spencer T., Carmel J., Hart R.B., Filbin M.T. The cytokine interleukin-6 is sufficient but not necessary to mimic the peripheral conditioning lesion effect on axonal growth. J. Neurosci. 2006, 26:5565-5573.
-
(2006)
J. Neurosci.
, vol.26
, pp. 5565-5573
-
-
Cao, Z.1
Gao, Y.2
Bryson, J.B.3
Hou, J.4
Chaudhry, N.5
Siddiq, M.6
Martinez, J.7
Spencer, T.8
Carmel, J.9
Hart, R.B.10
Filbin, M.T.11
-
28
-
-
33750139963
-
Expression of neurotrophin-3 promotes axonal plasticity in the acute but not chronic injured spinal cord
-
Chen Q., Zhou L., Shine H.D. Expression of neurotrophin-3 promotes axonal plasticity in the acute but not chronic injured spinal cord. J. Neurotrauma 2006, 23:1254-1260.
-
(2006)
J. Neurotrauma
, vol.23
, pp. 1254-1260
-
-
Chen, Q.1
Zhou, L.2
Shine, H.D.3
-
29
-
-
73449128979
-
Safety and tolerability of putaminal AADC gene therapy for Parkinson disease
-
Christine C.W., Starr P.A., Larson P.S., Eberling J.L., Jagust W.J., Hawkins R.A., VanBrocklin H.F., Wright J.F., Bankiewicz K.S., Aminoff M.J. Safety and tolerability of putaminal AADC gene therapy for Parkinson disease. Neurology 2009, 73:1662-1669.
-
(2009)
Neurology
, vol.73
, pp. 1662-1669
-
-
Christine, C.W.1
Starr, P.A.2
Larson, P.S.3
Eberling, J.L.4
Jagust, W.J.5
Hawkins, R.A.6
VanBrocklin, H.F.7
Wright, J.F.8
Bankiewicz, K.S.9
Aminoff, M.J.10
-
30
-
-
0037175326
-
Replicate high-density rat genome oligonucleotide microarrays reveal hundreds of regulated genes in the dorsal root ganglion after peripheral nerve injury
-
Costigan M., Befort K., Karchewski L., Griffin R.S., D'Urso D., Allchorne A., Sitarski J., Mannion J.W., Pratt R.E., Woolf C.J. Replicate high-density rat genome oligonucleotide microarrays reveal hundreds of regulated genes in the dorsal root ganglion after peripheral nerve injury. BMC Neurosci. 2002, 3:16.
-
(2002)
BMC Neurosci.
, vol.3
, pp. 16
-
-
Costigan, M.1
Befort, K.2
Karchewski, L.3
Griffin, R.S.4
D'Urso, D.5
Allchorne, A.6
Sitarski, J.7
Mannion, J.W.8
Pratt, R.E.9
Woolf, C.J.10
-
31
-
-
0019856865
-
Axonal elongation into peripheral nervous system "bridges" after central nervous system injury in adult rats
-
David S., Aguayo A.J. Axonal elongation into peripheral nervous system "bridges" after central nervous system injury in adult rats. Science 1981, 214:931-933.
-
(1981)
Science
, vol.214
, pp. 931-933
-
-
David, S.1
Aguayo, A.J.2
-
32
-
-
0032703535
-
Influence of the axotomy to cell body distance in rat rubrospinal and spinal motoneurons: differential regulation of GAP-43, tubulins, and neurofilament-M
-
Fernandes K.J., Fan D.P., Tsui B.J., Cassar S.L., Tetzlaff W. Influence of the axotomy to cell body distance in rat rubrospinal and spinal motoneurons: differential regulation of GAP-43, tubulins, and neurofilament-M. J. Comp. Neurol. 1999, 414:495-510.
-
(1999)
J. Comp. Neurol.
, vol.414
, pp. 495-510
-
-
Fernandes, K.J.1
Fan, D.P.2
Tsui, B.J.3
Cassar, S.L.4
Tetzlaff, W.5
-
33
-
-
0141499228
-
Myelin-associated inhibitors of axonal regeneration in the adult mammalian CNS
-
Filbin M.T. Myelin-associated inhibitors of axonal regeneration in the adult mammalian CNS. Nat. Rev. Neurosci. 2003, 4:703-713.
-
(2003)
Nat. Rev. Neurosci.
, vol.4
, pp. 703-713
-
-
Filbin, M.T.1
-
34
-
-
38649112309
-
CNS injury, glial scars, and inflammation: Inhibitory extracellular matrices and regeneration failure
-
Fitch M.T., Silver J. CNS injury, glial scars, and inflammation: Inhibitory extracellular matrices and regeneration failure. Exp. Neurol. 2008, 209:294-301.
-
(2008)
Exp. Neurol.
, vol.209
, pp. 294-301
-
-
Fitch, M.T.1
Silver, J.2
-
35
-
-
69249124531
-
Muscle injection of AAV-NT3 promotes anatomical reorganization of CST axons and improves behavioral outcome following SCI
-
Fortun J., Puzis R., Pearse D.D., Gage F.H., Bunge M.B. Muscle injection of AAV-NT3 promotes anatomical reorganization of CST axons and improves behavioral outcome following SCI. J. Neurotrauma 2009, 26:941-953.
-
(2009)
J. Neurotrauma
, vol.26
, pp. 941-953
-
-
Fortun, J.1
Puzis, R.2
Pearse, D.D.3
Gage, F.H.4
Bunge, M.B.5
-
36
-
-
8844263909
-
Activated CREB is sufficient to overcome inhibitors in myelin and promote spinal axon regeneration in vivo
-
Gao Y., Deng K., Hou J., Bryson J.B., Barco A., Nikulina E., Spencer T., Mellado W., Kandel E.R., Filbin M.T. Activated CREB is sufficient to overcome inhibitors in myelin and promote spinal axon regeneration in vivo. Neuron 2004, 44:609-621.
-
(2004)
Neuron
, vol.44
, pp. 609-621
-
-
Gao, Y.1
Deng, K.2
Hou, J.3
Bryson, J.B.4
Barco, A.5
Nikulina, E.6
Spencer, T.7
Mellado, W.8
Kandel, E.R.9
Filbin, M.T.10
-
37
-
-
0347694856
-
Neurotrophins elevate cAMP to reach a threshold required to overcome inhibition by MAG through extracellular signal-regulated kinase-dependent inhibition of phosphodiesterase
-
Gao Y., Nikulina E., Mellado W., Filbin M.T. Neurotrophins elevate cAMP to reach a threshold required to overcome inhibition by MAG through extracellular signal-regulated kinase-dependent inhibition of phosphodiesterase. J. Neurosci. 2003, 23:11770-11777.
-
(2003)
J. Neurosci.
, vol.23
, pp. 11770-11777
-
-
Gao, Y.1
Nikulina, E.2
Mellado, W.3
Filbin, M.T.4
-
38
-
-
0028965811
-
CNS gene delivery by retrograde transport of recombinant replication-defective adenoviruses
-
Ghadge G.D., Roos R.P., Kang U.J., Wollmann R., Fishman P.S., Kalynych A.M., Barr E., Leiden J.M. CNS gene delivery by retrograde transport of recombinant replication-defective adenoviruses. Gene Ther. 1995, 2:132-137.
-
(1995)
Gene Ther.
, vol.2
, pp. 132-137
-
-
Ghadge, G.D.1
Roos, R.P.2
Kang, U.J.3
Wollmann, R.4
Fishman, P.S.5
Kalynych, A.M.6
Barr, E.7
Leiden, J.M.8
-
39
-
-
0029989784
-
BDNF and NT-3, but not NGF, prevent axotomy-induced death of rat corticospinal neurons in vivo
-
Giehl K.M., Tetzlaff W. BDNF and NT-3, but not NGF, prevent axotomy-induced death of rat corticospinal neurons in vivo. Eur. J. Neurosci. 1996, 8:1167-1175.
-
(1996)
Eur. J. Neurosci.
, vol.8
, pp. 1167-1175
-
-
Giehl, K.M.1
Tetzlaff, W.2
-
40
-
-
0034602727
-
Adenoviral and adeno-associated viral transfer of genes to the peripheral nervous system
-
Glatzel M., Flechsig E., Navarro B., Klein M.A., Paterna J.C., Bueler H., Aguzzi A. Adenoviral and adeno-associated viral transfer of genes to the peripheral nervous system. Proc. Natl Acad. Sci. USA 2000, 97:442-447.
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 442-447
-
-
Glatzel, M.1
Flechsig, E.2
Navarro, B.3
Klein, M.A.4
Paterna, J.C.5
Bueler, H.6
Aguzzi, A.7
-
41
-
-
0037036144
-
Amacrine-signaled loss of intrinsic axon growth ability by retinal ganglion cells
-
Goldberg J.L., Klassen M.P., Hua Y., Barres B.A. Amacrine-signaled loss of intrinsic axon growth ability by retinal ganglion cells. Science 2002, 296:1860-1864.
-
(2002)
Science
, vol.296
, pp. 1860-1864
-
-
Goldberg, J.L.1
Klassen, M.P.2
Hua, Y.3
Barres, B.A.4
-
42
-
-
0026720075
-
Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
-
Gossen M., Bujard H. Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc. Natl Acad. Sci. USA 1992, 89:5547-5551.
-
(1992)
Proc. Natl Acad. Sci. USA
, vol.89
, pp. 5547-5551
-
-
Gossen, M.1
Bujard, H.2
-
43
-
-
0029022369
-
Transcriptional activation by tetracyclines in mammalian cells
-
Gossen M., Freundlieb S., Bender G., Muller G., Hillen W., Bujard H. Transcriptional activation by tetracyclines in mammalian cells. Science 1995, 268:1766-1769.
-
(1995)
Science
, vol.268
, pp. 1766-1769
-
-
Gossen, M.1
Freundlieb, S.2
Bender, G.3
Muller, G.4
Hillen, W.5
Bujard, H.6
-
44
-
-
77649273563
-
Directed evolution of a novel adeno-associated virus (AAV) vector that crosses the seizure-compromised blood-brain barrier (BBB)
-
Gray S.J., Blake B.L., Criswell H.E., Nicolson S.C., Samulski R.J., McCown T.J. Directed evolution of a novel adeno-associated virus (AAV) vector that crosses the seizure-compromised blood-brain barrier (BBB). Mol. Ther. 2010, 18:570-578.
-
(2010)
Mol. Ther.
, vol.18
, pp. 570-578
-
-
Gray, S.J.1
Blake, B.L.2
Criswell, H.E.3
Nicolson, S.C.4
Samulski, R.J.5
McCown, T.J.6
-
45
-
-
16944366150
-
Cellular delivery of neurotrophin-3 promotes corticospinal axonal growth and partial functional recovery after spinal cord injury
-
Grill R., Murai K., Blesch A., Gage F.H., Tuszynski M.H. Cellular delivery of neurotrophin-3 promotes corticospinal axonal growth and partial functional recovery after spinal cord injury. J. Neurosci. 1997, 17:5560-5572.
-
(1997)
J. Neurosci.
, vol.17
, pp. 5560-5572
-
-
Grill, R.1
Murai, K.2
Blesch, A.3
Gage, F.H.4
Tuszynski, M.H.5
-
46
-
-
0031408944
-
Robust growth of chronically injured spinal cord axons induced by grafts of genetically modified NGF-secreting cells
-
Grill R.J., Blesch A., Tuszynski M.H. Robust growth of chronically injured spinal cord axons induced by grafts of genetically modified NGF-secreting cells. Exp. Neurol. 1997, 148:444-452.
-
(1997)
Exp. Neurol.
, vol.148
, pp. 444-452
-
-
Grill, R.J.1
Blesch, A.2
Tuszynski, M.H.3
-
47
-
-
1542369977
-
From virus evolution to vector revolution: use of naturally occurring serotypes of adeno-associated virus (AAV) as novel vectors for human gene therapy
-
Grimm D., Kay M.A. From virus evolution to vector revolution: use of naturally occurring serotypes of adeno-associated virus (AAV) as novel vectors for human gene therapy. Curr. Gene Ther. 2003, 3:281-304.
-
(2003)
Curr. Gene Ther.
, vol.3
, pp. 281-304
-
-
Grimm, D.1
Kay, M.A.2
-
48
-
-
0030953519
-
Gene therapy of murine motor neuron disease using adenoviral vectors for neurotrophic factors
-
Haase G., Kennel P., Pettmann B., Vigne E., Akli S., Revah F., Schmalbruch H., Kahn A. Gene therapy of murine motor neuron disease using adenoviral vectors for neurotrophic factors. Nat. Med. 1997, 3:429-436.
-
(1997)
Nat. Med.
, vol.3
, pp. 429-436
-
-
Haase, G.1
Kennel, P.2
Pettmann, B.3
Vigne, E.4
Akli, S.5
Revah, F.6
Schmalbruch, H.7
Kahn, A.8
-
49
-
-
0035885111
-
Transplants of cells genetically modified to express neurotrophin-3 rescue axotomized Clarke's nucleus neurons after spinal cord hemisection in adult rats
-
Himes B.T., Liu Y., Solowska J.M., Snyder E.Y., Fischer I., Tessler A. Transplants of cells genetically modified to express neurotrophin-3 rescue axotomized Clarke's nucleus neurons after spinal cord hemisection in adult rats. J. Neurosci. Res. 2001, 65:549-564.
-
(2001)
J. Neurosci. Res.
, vol.65
, pp. 549-564
-
-
Himes, B.T.1
Liu, Y.2
Solowska, J.M.3
Snyder, E.Y.4
Fischer, I.5
Tessler, A.6
-
50
-
-
0037133174
-
Marrow stromal cells form guiding strands in the injured spinal cord and promote recovery
-
Hofstetter C.P., Schwarz E.J., Hess D., Widenfalk J., El Manira A., Prockop D.J., Olson L. Marrow stromal cells form guiding strands in the injured spinal cord and promote recovery. Proc. Natl Acad. Sci. USA 2002, 99:2199-2204.
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 2199-2204
-
-
Hofstetter, C.P.1
Schwarz, E.J.2
Hess, D.3
Widenfalk, J.4
El Manira, A.5
Prockop, D.J.6
Olson, L.7
-
51
-
-
77955174111
-
-
Mol Ther
-
Hollis E.R., Jamshidi P., Lorenzana A.O., Lee J.K., Gray S.J., Samulski R.J., Zheng B., Tuszynski M.H. Transient Demyelination Increases the Efficiency of Retrograde AAV Transduction 2010, Mol Ther.
-
(2010)
Transient Demyelination Increases the Efficiency of Retrograde AAV Transduction
-
-
Hollis, E.R.1
Jamshidi, P.2
Lorenzana, A.O.3
Lee, J.K.4
Gray, S.J.5
Samulski, R.J.6
Zheng, B.7
Tuszynski, M.H.8
-
52
-
-
66349113194
-
Induction of corticospinal regeneration by lentiviral trkB-induced Erk activation
-
Hollis E.R., Jamshidi P., Low K., Blesch A., Tuszynski M.H. Induction of corticospinal regeneration by lentiviral trkB-induced Erk activation. Proc. Natl Acad. Sci. USA 2009, 106:7215-7220.
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 7215-7220
-
-
Hollis, E.R.1
Jamshidi, P.2
Low, K.3
Blesch, A.4
Tuszynski, M.H.5
-
53
-
-
38649139370
-
Efficient retrograde neuronal transduction utilizing self-complementary AAV1
-
Hollis E.R., Kadoya K., Hirsch M., Samulski R.J., Tuszynski M.H. Efficient retrograde neuronal transduction utilizing self-complementary AAV1. Mol. Ther. 2008, 16:296-301.
-
(2008)
Mol. Ther.
, vol.16
, pp. 296-301
-
-
Hollis, E.R.1
Kadoya, K.2
Hirsch, M.3
Samulski, R.J.4
Tuszynski, M.H.5
-
54
-
-
57449092483
-
IGF-I gene delivery promotes corticospinal neuronal survival but not regeneration after adult CNS injury
-
Hollis E.R., Lu P., Blesch A., Tuszynski M.H. IGF-I gene delivery promotes corticospinal neuronal survival but not regeneration after adult CNS injury. Exp. Neurol. 2009, 215:53-59.
-
(2009)
Exp. Neurol.
, vol.215
, pp. 53-59
-
-
Hollis, E.R.1
Lu, P.2
Blesch, A.3
Tuszynski, M.H.4
-
55
-
-
0036434324
-
Transplants of fibroblasts genetically modified to express BDNF promote axonal regeneration from supraspinal neurons following chronic spinal cord injury
-
Jin Y., Fischer I., Tessler A., Houle J.D. Transplants of fibroblasts genetically modified to express BDNF promote axonal regeneration from supraspinal neurons following chronic spinal cord injury. Exp. Neurol. 2002, 177:265-275.
-
(2002)
Exp. Neurol.
, vol.177
, pp. 265-275
-
-
Jin, Y.1
Fischer, I.2
Tessler, A.3
Houle, J.D.4
-
56
-
-
0034438394
-
Fibroblasts genetically modified to produce BDNF support regrowth of chronically injured serotonergic axons
-
Jin Y., Tessler A., Fischer I., Houle J.D. Fibroblasts genetically modified to produce BDNF support regrowth of chronically injured serotonergic axons. Neurorehabil. Neural Repair 2000, 14:311-317.
-
(2000)
Neurorehabil. Neural Repair
, vol.14
, pp. 311-317
-
-
Jin, Y.1
Tessler, A.2
Fischer, I.3
Houle, J.D.4
-
57
-
-
41149088114
-
Axon growth across a lesion site along a preformed guidance pathway in the brain
-
Jin Y., Ziemba K.S., Smith G.M. Axon growth across a lesion site along a preformed guidance pathway in the brain. Exp. Neurol. 2008, 210:521-530.
-
(2008)
Exp. Neurol.
, vol.210
, pp. 521-530
-
-
Jin, Y.1
Ziemba, K.S.2
Smith, G.M.3
-
58
-
-
70350203996
-
Combined intrinsic and extrinsic neuronal mechanisms facilitate bridging axonal regeneration one year after spinal cord injury
-
Kadoya K., Tsukada S., Lu P., Coppola G., Geschwind D., Filbin M., Blesch A., Tuszynski M.H. Combined intrinsic and extrinsic neuronal mechanisms facilitate bridging axonal regeneration one year after spinal cord injury. Neuron 2009, 64:165-172.
-
(2009)
Neuron
, vol.64
, pp. 165-172
-
-
Kadoya, K.1
Tsukada, S.2
Lu, P.3
Coppola, G.4
Geschwind, D.5
Filbin, M.6
Blesch, A.7
Tuszynski, M.H.8
-
59
-
-
34250683023
-
Safety and tolerability of gene therapy with an adeno-associated virus (AAV) borne GAD gene for Parkinson's disease: an open label, phase I trial
-
Kaplitt M.G., Feigin A., Tang C., Fitzsimons H.L., Mattis P., Lawlor P.A., Bland R.J., Young D., Strybing K., Eidelberg D., During M.J. Safety and tolerability of gene therapy with an adeno-associated virus (AAV) borne GAD gene for Parkinson's disease: an open label, phase I trial. Lancet 2007, 369:2097-2105.
-
(2007)
Lancet
, vol.369
, pp. 2097-2105
-
-
Kaplitt, M.G.1
Feigin, A.2
Tang, C.3
Fitzsimons, H.L.4
Mattis, P.5
Lawlor, P.A.6
Bland, R.J.7
Young, D.8
Strybing, K.9
Eidelberg, D.10
During, M.J.11
-
60
-
-
0042528664
-
Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model
-
Kaspar B.K., Llado J., Sherkat N., Rothstein J.D., Gage F.H. Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model. Science 2003, 301:839-842.
-
(2003)
Science
, vol.301
, pp. 839-842
-
-
Kaspar, B.K.1
Llado, J.2
Sherkat, N.3
Rothstein, J.D.4
Gage, F.H.5
-
61
-
-
0029361836
-
Targeting and gene expression in spinal cord motor neurons following intramuscular inoculation of an HSV-1 vector
-
Keir S.D., Mitchell W.J., Feldman L.T., Martin J.R. Targeting and gene expression in spinal cord motor neurons following intramuscular inoculation of an HSV-1 vector. J. Neurovirol. 1995, 1:259-267.
-
(1995)
J. Neurovirol.
, vol.1
, pp. 259-267
-
-
Keir, S.D.1
Mitchell, W.J.2
Feldman, L.T.3
Martin, J.R.4
-
62
-
-
33746190683
-
A common mechanism for cytoplasmic dynein-dependent microtubule binding shared among adeno-associated virus and adenovirus serotypes
-
Kelkar S., De B.P., Gao G., Wilson J.M., Crystal R.G., Leopold P.L. A common mechanism for cytoplasmic dynein-dependent microtubule binding shared among adeno-associated virus and adenovirus serotypes. J. Virol. 2006, 80:7781-7785.
-
(2006)
J. Virol.
, vol.80
, pp. 7781-7785
-
-
Kelkar, S.1
De, B.P.2
Gao, G.3
Wilson, J.M.4
Crystal, R.G.5
Leopold, P.L.6
-
63
-
-
0016774093
-
Structural and functional evidence of plasticity in the central nervous system
-
Kerr F.W. Structural and functional evidence of plasticity in the central nervous system. Exp. Neurol. 1975, 48:16-31.
-
(1975)
Exp. Neurol.
, vol.48
, pp. 16-31
-
-
Kerr, F.W.1
-
64
-
-
0031467240
-
BDNF and NT-4/5 prevent atrophy of rat rubrospinal neurons after cervical axotomy, stimulate GAP-43 and Talpha1-tubulin mRNA expression, and promote axonal regeneration
-
Kobayashi N.R., Fan D.P., Giehl K.M., Bedard A.M., Wiegand S.J., Tetzlaff W. BDNF and NT-4/5 prevent atrophy of rat rubrospinal neurons after cervical axotomy, stimulate GAP-43 and Talpha1-tubulin mRNA expression, and promote axonal regeneration. J. Neurosci. 1997, 17:9583-9595.
-
(1997)
J. Neurosci.
, vol.17
, pp. 9583-9595
-
-
Kobayashi, N.R.1
Fan, D.P.2
Giehl, K.M.3
Bedard, A.M.4
Wiegand, S.J.5
Tetzlaff, W.6
-
65
-
-
34248326047
-
Brain-derived neurotrophic factor gene transfer with adeno-associated viral and lentiviral vectors prevents rubrospinal neuronal atrophy and stimulates regeneration-associated gene expression after acute cervical spinal cord injury
-
Kwon B.K., Liu J., Lam C., Plunet W., Oschipok L.W., Hauswirth W., Di Polo A., Blesch A., Tetzlaff W. Brain-derived neurotrophic factor gene transfer with adeno-associated viral and lentiviral vectors prevents rubrospinal neuronal atrophy and stimulates regeneration-associated gene expression after acute cervical spinal cord injury. Spine 2007, 32:1164-1173.
-
(2007)
Spine
, vol.32
, pp. 1164-1173
-
-
Kwon, B.K.1
Liu, J.2
Lam, C.3
Plunet, W.4
Oschipok, L.W.5
Hauswirth, W.6
Di Polo, A.7
Blesch, A.8
Tetzlaff, W.9
-
66
-
-
0037022673
-
Survival and regeneration of rubrospinal neurons 1 year after spinal cord injury
-
Kwon B.K., Liu J., Messerer C., Kobayashi N.R., McGraw J., Oschipok L., Tetzlaff W. Survival and regeneration of rubrospinal neurons 1 year after spinal cord injury. Proc. Natl Acad. Sci. USA 2002, 99:3246-3251.
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 3246-3251
-
-
Kwon, B.K.1
Liu, J.2
Messerer, C.3
Kobayashi, N.R.4
McGraw, J.5
Oschipok, L.6
Tetzlaff, W.7
-
67
-
-
19344365362
-
Lineage-restricted neural precursors survive, migrate, and differentiate following transplantation into the injured adult spinal cord
-
Lepore A.C., Fischer I. Lineage-restricted neural precursors survive, migrate, and differentiate following transplantation into the injured adult spinal cord. Exp. Neurol. 2005, 194:230-242.
-
(2005)
Exp. Neurol.
, vol.194
, pp. 230-242
-
-
Lepore, A.C.1
Fischer, I.2
-
68
-
-
0030769193
-
Repair of adult rat corticospinal tract by transplants of olfactory ensheathing cells
-
Li Y., Field M., Raisman G. Repair of adult rat corticospinal tract by transplants of olfactory ensheathing cells. Science 1997, 277:2000-2002.
-
(1997)
Science
, vol.277
, pp. 2000-2002
-
-
Li, Y.1
Field, M.2
Raisman, G.3
-
69
-
-
0028246867
-
Schwann cells induce sprouting in motor and sensory axons in the adult rat spinal cord
-
Li Y., Raisman G. Schwann cells induce sprouting in motor and sensory axons in the adult rat spinal cord. J. Neurosci. 1994, 14:4050-4063.
-
(1994)
J. Neurosci.
, vol.14
, pp. 4050-4063
-
-
Li, Y.1
Raisman, G.2
-
70
-
-
0032818773
-
Intraspinal delivery of neurotrophin-3 using neural stem cells genetically modified by recombinant retrovirus
-
Liu Y., Himes B.T., Solowska J., Moul J., Chow S.Y., Park K.I., Tessler A., Murray M., Snyder E.Y., Fischer I. Intraspinal delivery of neurotrophin-3 using neural stem cells genetically modified by recombinant retrovirus. Exp. Neurol. 1999, 158:9-26.
-
(1999)
Exp. Neurol.
, vol.158
, pp. 9-26
-
-
Liu, Y.1
Himes, B.T.2
Solowska, J.3
Moul, J.4
Chow, S.Y.5
Park, K.I.6
Tessler, A.7
Murray, M.8
Snyder, E.Y.9
Fischer, I.10
-
71
-
-
0033151593
-
Transplants of fibroblasts genetically modified to express brain-derived neurotrophic factor promote regeneration of adult rat rubrospinal axons and recovery of forelimb function
-
Liu Y., Kim D., Himes B.T., Chow S.Y., Schallert T., Murray M., Tessler A., Fischer I. Transplants of fibroblasts genetically modified to express brain-derived neurotrophic factor promote regeneration of adult rat rubrospinal axons and recovery of forelimb function. J. Neurosci. 1999, 19:4370-4387.
-
(1999)
J. Neurosci.
, vol.19
, pp. 4370-4387
-
-
Liu, Y.1
Kim, D.2
Himes, B.T.3
Chow, S.Y.4
Schallert, T.5
Murray, M.6
Tessler, A.7
Fischer, I.8
-
72
-
-
77952430179
-
A dual promoter lentiviral vector for the in vivo evaluation of gene therapeutic approaches to axon regeneration after spinal cord injury
-
Low K., Blesch A., Herrmann J., Tuszynski M.H. A dual promoter lentiviral vector for the in vivo evaluation of gene therapeutic approaches to axon regeneration after spinal cord injury. Gene Ther. 2010, 17:577-591.
-
(2010)
Gene Ther.
, vol.17
, pp. 577-591
-
-
Low, K.1
Blesch, A.2
Herrmann, J.3
Tuszynski, M.H.4
-
73
-
-
38749097753
-
Netrin-1 is a novel myelin-associated inhibitor to axon growth
-
Low K., Culbertson M., Bradke F., Tessier-Lavigne M., Tuszynski M.H. Netrin-1 is a novel myelin-associated inhibitor to axon growth. J. Neurosci. 2008, 28:1099-1108.
-
(2008)
J. Neurosci.
, vol.28
, pp. 1099-1108
-
-
Low, K.1
Culbertson, M.2
Bradke, F.3
Tessier-Lavigne, M.4
Tuszynski, M.H.5
-
74
-
-
84859924050
-
-
Regeneration and bridging of long-descending motor axons after spinal cord injury. Abstract Viewer/Itinerary Planner. San Diego, CA: Society for Neuroscience, 2007. Online., Program No. 600.609.
-
Lu, P., Blesch, A., Graham, L., Yu, K., Culbertson, M., and Tuszynski, M. H., 2007. Regeneration and bridging of long-descending motor axons after spinal cord injury. Abstract Viewer/Itinerary Planner. San Diego, CA: Society for Neuroscience, 2007. Online., Program No. 600.609.
-
(2007)
-
-
Lu, P.1
Blesch, A.2
Graham, L.3
Yu, K.4
Culbertson, M.5
Tuszynski, M.H.6
-
75
-
-
0035817425
-
Neurotrophism without neurotropism: BDNF promotes survival but not growth of lesioned corticospinal neurons
-
Lu P., Blesch A., Tuszynski M.H. Neurotrophism without neurotropism: BDNF promotes survival but not growth of lesioned corticospinal neurons. J. Comp. Neurol. 2001, 436:456-470.
-
(2001)
J. Comp. Neurol.
, vol.436
, pp. 456-470
-
-
Lu, P.1
Blesch, A.2
Tuszynski, M.H.3
-
76
-
-
0038054469
-
Neural stem cells constitutively secrete neurotrophic factors and promote extensive host axonal growth after spinal cord injury
-
Lu P., Jones L.L., Snyder E.Y., Tuszynski M.H. Neural stem cells constitutively secrete neurotrophic factors and promote extensive host axonal growth after spinal cord injury. Exp. Neurol. 2003, 181:115-129.
-
(2003)
Exp. Neurol.
, vol.181
, pp. 115-129
-
-
Lu, P.1
Jones, L.L.2
Snyder, E.Y.3
Tuszynski, M.H.4
-
77
-
-
11844273931
-
BDNF-expressing marrow stromal cells support extensive axonal growth at sites of spinal cord injury
-
Lu P., Jones L.L., Tuszynski M.H. BDNF-expressing marrow stromal cells support extensive axonal growth at sites of spinal cord injury. Exp. Neurol. 2005, 191:344-360.
-
(2005)
Exp. Neurol.
, vol.191
, pp. 344-360
-
-
Lu, P.1
Jones, L.L.2
Tuszynski, M.H.3
-
78
-
-
33751433363
-
Axon regeneration through scars and into sites of chronic spinal cord injury
-
Lu P., Jones L.L., Tuszynski M.H. Axon regeneration through scars and into sites of chronic spinal cord injury. Exp. Neurol. 2007, 203:8-21.
-
(2007)
Exp. Neurol.
, vol.203
, pp. 8-21
-
-
Lu, P.1
Jones, L.L.2
Tuszynski, M.H.3
-
79
-
-
33751102887
-
Olfactory ensheathing cells do not exhibit unique migratory or axonal growth-promoting properties after spinal cord injury
-
Lu P., Yang H., Culbertson M., Graham L., Roskams A.J., Tuszynski M.H. Olfactory ensheathing cells do not exhibit unique migratory or axonal growth-promoting properties after spinal cord injury. J. Neurosci. 2006, 26:11120-11130.
-
(2006)
J. Neurosci.
, vol.26
, pp. 11120-11130
-
-
Lu, P.1
Yang, H.2
Culbertson, M.3
Graham, L.4
Roskams, A.J.5
Tuszynski, M.H.6
-
80
-
-
3242711266
-
Combinatorial therapy with neurotrophins and cAMP promotes axonal regeneration beyond sites of spinal cord injury
-
Lu P., Yang H., Jones L.L., Filbin M.T., Tuszynski M.H. Combinatorial therapy with neurotrophins and cAMP promotes axonal regeneration beyond sites of spinal cord injury. J. Neurosci. 2004, 24:6402-6409.
-
(2004)
J. Neurosci.
, vol.24
, pp. 6402-6409
-
-
Lu, P.1
Yang, H.2
Jones, L.L.3
Filbin, M.T.4
Tuszynski, M.H.5
-
81
-
-
0037079079
-
Neurotrophin-3 is required for appropriate establishment of thalamocortical connections
-
Ma L., Harada T., Harada C., Romero M., Hebert J.M., McConnell S.K., Parada L.F. Neurotrophin-3 is required for appropriate establishment of thalamocortical connections. Neuron 2002, 36:623-634.
-
(2002)
Neuron
, vol.36
, pp. 623-634
-
-
Ma, L.1
Harada, T.2
Harada, C.3
Romero, M.4
Hebert, J.M.5
McConnell, S.K.6
Parada, L.F.7
-
82
-
-
77950838482
-
CERE-110, an adeno-associated virus-based gene delivery vector expressing human nerve growth factor for the treatment of Alzheimer's disease
-
Mandel R.J. CERE-110, an adeno-associated virus-based gene delivery vector expressing human nerve growth factor for the treatment of Alzheimer's disease. Curr. Opin. Mol. Ther. 2010, 12:240-247.
-
(2010)
Curr. Opin. Mol. Ther.
, vol.12
, pp. 240-247
-
-
Mandel, R.J.1
-
83
-
-
41949110690
-
Safety and tolerability of intraputaminal delivery of CERE-120 (adeno-associated virus serotype 2-neurturin) to patients with idiopathic Parkinson's disease: an open-label, phase I trial
-
Marks W.J., Ostrem J.L., Verhagen L., Starr P.A., Larson P.S., Bakay R.A., Taylor R., Cahn-Weiner D.A., Stoessl A.J., Olanow C.W., Bartus R.T. Safety and tolerability of intraputaminal delivery of CERE-120 (adeno-associated virus serotype 2-neurturin) to patients with idiopathic Parkinson's disease: an open-label, phase I trial. Lancet Neurol. 2008, 7:400-408.
-
(2008)
Lancet Neurol.
, vol.7
, pp. 400-408
-
-
Marks, W.J.1
Ostrem, J.L.2
Verhagen, L.3
Starr, P.A.4
Larson, P.S.5
Bakay, R.A.6
Taylor, R.7
Cahn-Weiner, D.A.8
Stoessl, A.J.9
Olanow, C.W.10
Bartus, R.T.11
-
85
-
-
3843149566
-
Brain-derived neurotrophic factor is expressed in a gradient in the superior colliculus during development of the retinocollicular projection
-
Marotte L.R., Vidovic M., Wheeler E., Jhaveri S. Brain-derived neurotrophic factor is expressed in a gradient in the superior colliculus during development of the retinocollicular projection. Eur. J. Neurosci. 2004, 20:843-847.
-
(2004)
Eur. J. Neurosci.
, vol.20
, pp. 843-847
-
-
Marotte, L.R.1
Vidovic, M.2
Wheeler, E.3
Jhaveri, S.4
-
86
-
-
77950466299
-
Comparison of AAV serotypes for gene delivery to dorsal root ganglion neurons
-
Mason M.R., Ehlert E.M., Eggers R., Pool C.W., Hermening S., Huseinovic A., Timmermans E., Blits B., Verhaagen J. Comparison of AAV serotypes for gene delivery to dorsal root ganglion neurons. Mol. Ther. 2010, 18:715-724.
-
(2010)
Mol. Ther.
, vol.18
, pp. 715-724
-
-
Mason, M.R.1
Ehlert, E.M.2
Eggers, R.3
Pool, C.W.4
Hermening, S.5
Huseinovic, A.6
Timmermans, E.7
Blits, B.8
Verhaagen, J.9
-
87
-
-
0346777307
-
Adeno-associated virus terminal repeat (TR) mutant generates self-complementary vectors to overcome the rate-limiting step to transduction in vivo
-
McCarty D.M., Fu H., Monahan P.E., Toulson C.E., Naik P., Samulski R.J. Adeno-associated virus terminal repeat (TR) mutant generates self-complementary vectors to overcome the rate-limiting step to transduction in vivo. Gene Ther. 2003, 10:2112-2118.
-
(2003)
Gene Ther.
, vol.10
, pp. 2112-2118
-
-
McCarty, D.M.1
Fu, H.2
Monahan, P.E.3
Toulson, C.E.4
Naik, P.5
Samulski, R.J.6
-
88
-
-
0034882826
-
Self-complementary recombinant adeno-associated virus (scAAV) vectors promote efficient transduction independently of DNA synthesis
-
McCarty D.M., Monahan P.E., Samulski R.J. Self-complementary recombinant adeno-associated virus (scAAV) vectors promote efficient transduction independently of DNA synthesis. Gene Ther. 2001, 8:1248-1254.
-
(2001)
Gene Ther.
, vol.8
, pp. 1248-1254
-
-
McCarty, D.M.1
Monahan, P.E.2
Samulski, R.J.3
-
89
-
-
0032528159
-
Neurotrophin-3 and brain-derived neurotrophic factor induce oligodendrocyte proliferation and myelination of regenerating axons in the contused adult rat spinal cord
-
McTigue D.M., Horner P.J., Stokes B.T., Gage F.H. Neurotrophin-3 and brain-derived neurotrophic factor induce oligodendrocyte proliferation and myelination of regenerating axons in the contused adult rat spinal cord. J. Neurosci. 1998, 18:5354-5365.
-
(1998)
J. Neurosci.
, vol.18
, pp. 5354-5365
-
-
McTigue, D.M.1
Horner, P.J.2
Stokes, B.T.3
Gage, F.H.4
-
90
-
-
0031814388
-
Schwann cells genetically modified to secrete human BDNF promote enhanced axonal regrowth across transected adult rat spinal cord
-
Menei P., Montero-Menei C., Whittemore S.R., Bunge R.P., Bunge M.B. Schwann cells genetically modified to secrete human BDNF promote enhanced axonal regrowth across transected adult rat spinal cord. Eur. J. Neurosci. 1998, 10:607-621.
-
(1998)
Eur. J. Neurosci.
, vol.10
, pp. 607-621
-
-
Menei, P.1
Montero-Menei, C.2
Whittemore, S.R.3
Bunge, R.P.4
Bunge, M.B.5
-
91
-
-
77956626072
-
-
Signaling to transcription networks in the neuronal retrograde injury response. Sci Signal 3, ra53.
-
Michaelevski, I., Segal-Ruder, Y., Rozenbaum, M., Medzihradszky, K. F., Shalem, O., Coppola, G., Horn-Saban, S., Ben-Yaakov, K., Dagan, S. Y., Rishal, I., Geschwind, D. H., Pilpel, Y., Burlingame, A. L., and Fainzilber, M., 2010. Signaling to transcription networks in the neuronal retrograde injury response. Sci Signal 3, ra53.
-
(2010)
-
-
Michaelevski, I.1
Segal-Ruder, Y.2
Rozenbaum, M.3
Medzihradszky, K.F.4
Shalem, O.5
Coppola, G.6
Horn-Saban, S.7
Ben-Yaakov, K.8
Dagan, S.Y.9
Rishal, I.10
Geschwind, D.H.11
Pilpel, Y.12
Burlingame, A.L.13
Fainzilber, M.14
-
92
-
-
22044438251
-
Transplants of fibroblasts expressing BDNF and NT-3 promote recovery of bladder and hindlimb function following spinal contusion injury in rats
-
Mitsui T., Fischer I., Shumsky J.S., Murray M. Transplants of fibroblasts expressing BDNF and NT-3 promote recovery of bladder and hindlimb function following spinal contusion injury in rats. Exp. Neurol. 2005, 194:410-431.
-
(2005)
Exp. Neurol.
, vol.194
, pp. 410-431
-
-
Mitsui, T.1
Fischer, I.2
Shumsky, J.S.3
Murray, M.4
-
93
-
-
70349884323
-
KLF family members regulate intrinsic axon regeneration ability
-
Moore D.L., Blackmore M.G., Hu Y., Kaestner K.H., Bixby J.L., Lemmon V.P., Goldberg J.L. KLF family members regulate intrinsic axon regeneration ability. Science 2009, 326:298-301.
-
(2009)
Science
, vol.326
, pp. 298-301
-
-
Moore, D.L.1
Blackmore, M.G.2
Hu, Y.3
Kaestner, K.H.4
Bixby, J.L.5
Lemmon, V.P.6
Goldberg, J.L.7
-
94
-
-
0031036301
-
Fetal spinal cord transplants rescue some axotomized rubrospinal neurons from retrograde cell death in adult rats
-
Mori F., Himes B.T., Kowada M., Murray M., Tessler A. Fetal spinal cord transplants rescue some axotomized rubrospinal neurons from retrograde cell death in adult rats. Exp. Neurol. 1997, 143:45-60.
-
(1997)
Exp. Neurol.
, vol.143
, pp. 45-60
-
-
Mori, F.1
Himes, B.T.2
Kowada, M.3
Murray, M.4
Tessler, A.5
-
95
-
-
0037071890
-
Regeneration of sensory axons within the injured spinal cord induced by intraganglionic cAMP elevation
-
Neumann S., Bradke F., Tessier-Lavigne M., Basbaum A.I. Regeneration of sensory axons within the injured spinal cord induced by intraganglionic cAMP elevation. Neuron 2002, 34:885-893.
-
(2002)
Neuron
, vol.34
, pp. 885-893
-
-
Neumann, S.1
Bradke, F.2
Tessier-Lavigne, M.3
Basbaum, A.I.4
-
96
-
-
0347342426
-
Meningeal cell-derived semaphorin 3A inhibits neurite outgrowth
-
Niclou S.P., Franssen E.H., Ehlert E.M., Taniguchi M., Verhaagen J. Meningeal cell-derived semaphorin 3A inhibits neurite outgrowth. Mol. Cell. Neurosci. 2003, 24:902-912.
-
(2003)
Mol. Cell. Neurosci.
, vol.24
, pp. 902-912
-
-
Niclou, S.P.1
Franssen, E.H.2
Ehlert, E.M.3
Taniguchi, M.4
Verhaagen, J.5
-
97
-
-
33750492639
-
IGF-I specifically enhances axon outgrowth of corticospinal motor neurons
-
Ozdinler P.H., Macklis J.D. IGF-I specifically enhances axon outgrowth of corticospinal motor neurons. Nat. Neurosci. 2006, 9:1371-1381.
-
(2006)
Nat. Neurosci.
, vol.9
, pp. 1371-1381
-
-
Ozdinler, P.H.1
Macklis, J.D.2
-
98
-
-
55849108858
-
Promoting axon regeneration in the adult CNS by modulation of the PTEN/mTOR pathway
-
Park K.K., Liu K., Hu Y., Smith P.D., Wang C., Cai B., Xu B., Connolly L., Kramvis I., Sahin M., He Z. Promoting axon regeneration in the adult CNS by modulation of the PTEN/mTOR pathway. Science 2008, 322:963-966.
-
(2008)
Science
, vol.322
, pp. 963-966
-
-
Park, K.K.1
Liu, K.2
Hu, Y.3
Smith, P.D.4
Wang, C.5
Cai, B.6
Xu, B.7
Connolly, L.8
Kramvis, I.9
Sahin, M.10
He, Z.11
-
99
-
-
8144225167
-
Adult neural progenitor cells provide a permissive guiding substrate for corticospinal axon growth following spinal cord injury
-
Pfeifer K., Vroemen M., Blesch A., Weidner N. Adult neural progenitor cells provide a permissive guiding substrate for corticospinal axon growth following spinal cord injury. Eur. J. Neurosci. 2004, 20:1695-1704.
-
(2004)
Eur. J. Neurosci.
, vol.20
, pp. 1695-1704
-
-
Pfeifer, K.1
Vroemen, M.2
Blesch, A.3
Weidner, N.4
-
100
-
-
0036218099
-
Promoting axonal regeneration in the central nervous system by enhancing the cell body response to axotomy
-
Plunet W., Kwon B.K., Tetzlaff W. Promoting axonal regeneration in the central nervous system by enhancing the cell body response to axotomy. J. Neurosci. Res. 2002, 68:1-6.
-
(2002)
J. Neurosci. Res.
, vol.68
, pp. 1-6
-
-
Plunet, W.1
Kwon, B.K.2
Tetzlaff, W.3
-
101
-
-
67650497872
-
Damage control in the nervous system: beware the immune system in spinal cord injury
-
Popovich P., McTigue D. Damage control in the nervous system: beware the immune system in spinal cord injury. Nat. Med. 2009, 15:736-737.
-
(2009)
Nat. Med.
, vol.15
, pp. 736-737
-
-
Popovich, P.1
McTigue, D.2
-
102
-
-
14044250276
-
Conditioning injury-induced spinal axon regeneration requires signal transducer and activator of transcription 3 activation
-
Qiu J., Cafferty W.B., McMahon S.B., Thompson S.W. Conditioning injury-induced spinal axon regeneration requires signal transducer and activator of transcription 3 activation. J. Neurosci. 2005, 25:1645-1653.
-
(2005)
J. Neurosci.
, vol.25
, pp. 1645-1653
-
-
Qiu, J.1
Cafferty, W.B.2
McMahon, S.B.3
Thompson, S.W.4
-
103
-
-
0037071880
-
Spinal axon regeneration induced by elevation of cyclic AMP
-
Qiu J., Cai D., Dai H., McAtee M., Hoffman P.N., Bregman B.S., Filbin M.T. Spinal axon regeneration induced by elevation of cyclic AMP. Neuron 2002, 34:895-903.
-
(2002)
Neuron
, vol.34
, pp. 895-903
-
-
Qiu, J.1
Cai, D.2
Dai, H.3
McAtee, M.4
Hoffman, P.N.5
Bregman, B.S.6
Filbin, M.T.7
-
104
-
-
0015937791
-
A quantitative investigation of the development of collateral reinnervation after partial deafferentation of the septal nuclei
-
Raisman G., Field P.M. A quantitative investigation of the development of collateral reinnervation after partial deafferentation of the septal nuclei. Brain Res. 1973, 50:241-264.
-
(1973)
Brain Res.
, vol.50
, pp. 241-264
-
-
Raisman, G.1
Field, P.M.2
-
105
-
-
0033757632
-
Functional recovery of paraplegic rats and motor axon regeneration in their spinal cords by olfactory ensheathing glia
-
Ramon-Cueto A., Cordero M.I., Santos-Benito F.F., Avila J. Functional recovery of paraplegic rats and motor axon regeneration in their spinal cords by olfactory ensheathing glia. Neuron 2000, 25:425-435.
-
(2000)
Neuron
, vol.25
, pp. 425-435
-
-
Ramon-Cueto, A.1
Cordero, M.I.2
Santos-Benito, F.F.3
Avila, J.4
-
106
-
-
0028108704
-
Regeneration into the spinal cord of transected dorsal root axons is promoted by ensheathing glia transplants
-
Ramon-Cueto A., Nieto-Sampedro M. Regeneration into the spinal cord of transected dorsal root axons is promoted by ensheathing glia transplants. Exp. Neurol. 1994, 127:232-244.
-
(1994)
Exp. Neurol.
, vol.127
, pp. 232-244
-
-
Ramon-Cueto, A.1
Nieto-Sampedro, M.2
-
107
-
-
0018908523
-
Axons from CNS neurons regenerate into PNS grafts
-
Richardson P.M., McGuinness U.M., Aguayo A.J. Axons from CNS neurons regenerate into PNS grafts. Nature 1980, 284:264-265.
-
(1980)
Nature
, vol.284
, pp. 264-265
-
-
Richardson, P.M.1
McGuinness, U.M.2
Aguayo, A.J.3
-
108
-
-
38649092415
-
Olfactory ensheathing cell transplantation following spinal cord injury: hype or hope?
-
Richter M.W., Roskams A.J. Olfactory ensheathing cell transplantation following spinal cord injury: hype or hope?. Exp. Neurol. 2008, 209:353-367.
-
(2008)
Exp. Neurol.
, vol.209
, pp. 353-367
-
-
Richter, M.W.1
Roskams, A.J.2
-
109
-
-
0035503328
-
Functional regeneration of chronically injured sensory afferents into adult spinal cord after neurotrophin gene therapy
-
Romero M.I., Rangappa N., Garry M.G., Smith G.M. Functional regeneration of chronically injured sensory afferents into adult spinal cord after neurotrophin gene therapy. J. Neurosci. 2001, 21:8408-8416.
-
(2001)
J. Neurosci.
, vol.21
, pp. 8408-8416
-
-
Romero, M.I.1
Rangappa, N.2
Garry, M.G.3
Smith, G.M.4
-
110
-
-
12144288408
-
Adeno-associated viral vector-mediated gene transfer of brain-derived neurotrophic factor reverses atrophy of rubrospinal neurons following both acute and chronic spinal cord injury
-
Ruitenberg M.J., Blits B., Dijkhuizen P.A., te Beek E.T., Bakker A., van Heerikhuize J.J., Pool C.W., Hermens W.T., Boer G.J., Verhaagen J. Adeno-associated viral vector-mediated gene transfer of brain-derived neurotrophic factor reverses atrophy of rubrospinal neurons following both acute and chronic spinal cord injury. Neurobiol. Dis. 2004, 15:394-406.
-
(2004)
Neurobiol. Dis.
, vol.15
, pp. 394-406
-
-
Ruitenberg, M.J.1
Blits, B.2
Dijkhuizen, P.A.3
te Beek, E.T.4
Bakker, A.5
van Heerikhuize, J.J.6
Pool, C.W.7
Hermens, W.T.8
Boer, G.J.9
Verhaagen, J.10
-
111
-
-
16844384738
-
NT-3 expression from engineered olfactory ensheathing glia promotes spinal sparing and regeneration
-
Ruitenberg M.J., Levison D.B., Lee S.V., Verhaagen J., Harvey A.R., Plant G.W. NT-3 expression from engineered olfactory ensheathing glia promotes spinal sparing and regeneration. Brain 2005, 128:839-853.
-
(2005)
Brain
, vol.128
, pp. 839-853
-
-
Ruitenberg, M.J.1
Levison, D.B.2
Lee, S.V.3
Verhaagen, J.4
Harvey, A.R.5
Plant, G.W.6
-
112
-
-
0043127466
-
Ex vivo adenoviral vector-mediated neurotrophin gene transfer to olfactory ensheathing glia: effects on rubrospinal tract regeneration, lesion size, and functional recovery after implantation in the injured rat spinal cord
-
Ruitenberg M.J., Plant G.W., Hamers F.P., Wortel J., Blits B., Dijkhuizen P.A., Gispen W.H., Boer G.J., Verhaagen J. Ex vivo adenoviral vector-mediated neurotrophin gene transfer to olfactory ensheathing glia: effects on rubrospinal tract regeneration, lesion size, and functional recovery after implantation in the injured rat spinal cord. J. Neurosci. 2003, 23:7045-7058.
-
(2003)
J. Neurosci.
, vol.23
, pp. 7045-7058
-
-
Ruitenberg, M.J.1
Plant, G.W.2
Hamers, F.P.3
Wortel, J.4
Blits, B.5
Dijkhuizen, P.A.6
Gispen, W.H.7
Boer, G.J.8
Verhaagen, J.9
-
113
-
-
0028115777
-
Neurotrophin-3 enhances sprouting of corticospinal tract during development and after adult spinal cord lesion
-
Schnell L., Schneider R., Kolbeck R., Barde Y.A., Schwab M.E. Neurotrophin-3 enhances sprouting of corticospinal tract during development and after adult spinal cord lesion. Nature 1994, 367:170-173.
-
(1994)
Nature
, vol.367
, pp. 170-173
-
-
Schnell, L.1
Schneider, R.2
Kolbeck, R.3
Barde, Y.A.4
Schwab, M.E.5
-
115
-
-
34547484768
-
ATF3 increases the intrinsic growth state of DRG neurons to enhance peripheral nerve regeneration
-
Seijffers R., Mills C.D., Woolf C.J. ATF3 increases the intrinsic growth state of DRG neurons to enhance peripheral nerve regeneration. J. Neurosci. 2007, 27:7911-7920.
-
(2007)
J. Neurosci.
, vol.27
, pp. 7911-7920
-
-
Seijffers, R.1
Mills, C.D.2
Woolf, C.J.3
-
116
-
-
0742288565
-
Regeneration beyond the glial scar
-
Silver J., Miller J.H. Regeneration beyond the glial scar. Nat. Rev. Neurosci. 2004, 5:146-156.
-
(2004)
Nat. Rev. Neurosci.
, vol.5
, pp. 146-156
-
-
Silver, J.1
Miller, J.H.2
-
117
-
-
0031029782
-
A transcription-dependent switch controls competence of adult neurons for distinct modes of axon growth
-
Smith D.S., Skene J.H. A transcription-dependent switch controls competence of adult neurons for distinct modes of axon growth. J. Neurosci. 1997, 17:646-658.
-
(1997)
J. Neurosci.
, vol.17
, pp. 646-658
-
-
Smith, D.S.1
Skene, J.H.2
-
118
-
-
34347387360
-
Identification of candidate transcriptional modulators involved in successful regeneration after nerve injury
-
Stam F.J., MacGillavry H.D., Armstrong N.J., de Gunst M.C., Zhang Y., van Kesteren R.E., Smit A.B., Verhaagen J. Identification of candidate transcriptional modulators involved in successful regeneration after nerve injury. Eur. J. Neurosci. 2007, 25:3629-3637.
-
(2007)
Eur. J. Neurosci.
, vol.25
, pp. 3629-3637
-
-
Stam, F.J.1
MacGillavry, H.D.2
Armstrong, N.J.3
de Gunst, M.C.4
Zhang, Y.5
van Kesteren, R.E.6
Smit, A.B.7
Verhaagen, J.8
-
119
-
-
0026719173
-
Fetal grafts alter chronic behavioral outcome after contusion damage to the adult rat spinal cord
-
Stokes B.T., Reier P.J. Fetal grafts alter chronic behavioral outcome after contusion damage to the adult rat spinal cord. Exp. Neurol. 1992, 116:1-12.
-
(1992)
Exp. Neurol.
, vol.116
, pp. 1-12
-
-
Stokes, B.T.1
Reier, P.J.2
-
120
-
-
33646403729
-
Intrathecal long-term gene expression by self-complementary adeno-associated virus type 1 suitable for chronic pain studies in rats
-
Storek B., Harder N.M., Banck M.S., Wang C., McCarty D.M., Janssen W.G., Morrison J.H., Walsh C.E., Beutler A.S. Intrathecal long-term gene expression by self-complementary adeno-associated virus type 1 suitable for chronic pain studies in rats. Mol. Pain 2006, 2:4.
-
(2006)
Mol. Pain
, vol.2
, pp. 4
-
-
Storek, B.1
Harder, N.M.2
Banck, M.S.3
Wang, C.4
McCarty, D.M.5
Janssen, W.G.6
Morrison, J.H.7
Walsh, C.E.8
Beutler, A.S.9
-
121
-
-
38949151650
-
Sensory neuron targeting by self-complementary AAV8 via lumbar puncture for chronic pain
-
Storek B., Reinhardt M., Wang C., Janssen W.G., Harder N.M., Banck M.S., Morrison J.H., Beutler A.S. Sensory neuron targeting by self-complementary AAV8 via lumbar puncture for chronic pain. Proc. Natl Acad. Sci. USA 2008, 105:1055-1060.
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 1055-1060
-
-
Storek, B.1
Reinhardt, M.2
Wang, C.3
Janssen, W.G.4
Harder, N.M.5
Banck, M.S.6
Morrison, J.H.7
Beutler, A.S.8
-
122
-
-
34249828947
-
Targeting sensory axon regeneration in adult spinal cord
-
Tang X.Q., Heron P., Mashburn C., Smith G.M. Targeting sensory axon regeneration in adult spinal cord. J. Neurosci. 2007, 27:6068-6078.
-
(2007)
J. Neurosci.
, vol.27
, pp. 6068-6078
-
-
Tang, X.Q.1
Heron, P.2
Mashburn, C.3
Smith, G.M.4
-
123
-
-
0742287916
-
Semaphorin3A inhibits nerve growth factor-induced sprouting of nociceptive afferents in adult rat spinal cord
-
Tang X.Q., Tanelian D.L., Smith G.M. Semaphorin3A inhibits nerve growth factor-induced sprouting of nociceptive afferents in adult rat spinal cord. J. Neurosci. 2004, 24:819-827.
-
(2004)
J. Neurosci.
, vol.24
, pp. 819-827
-
-
Tang, X.Q.1
Tanelian, D.L.2
Smith, G.M.3
-
124
-
-
33748887028
-
Neurotrophin-3 gradients established by lentiviral gene delivery promote short-distance axonal bridging beyond cellular grafts in the injured spinal cord
-
Taylor L., Jones L., Tuszynski M.H., Blesch A. Neurotrophin-3 gradients established by lentiviral gene delivery promote short-distance axonal bridging beyond cellular grafts in the injured spinal cord. J. Neurosci. 2006, 26:9713-9721.
-
(2006)
J. Neurosci.
, vol.26
, pp. 9713-9721
-
-
Taylor, L.1
Jones, L.2
Tuszynski, M.H.3
Blesch, A.4
-
125
-
-
34247271439
-
Comparative analysis of adeno-associated viral vector serotypes 1, 2, 5, 7, and 8 in mouse brain
-
Taymans J.M., Vandenberghe L.H., Haute C.V., Thiry I., Deroose C.M., Mortelmans L., Wilson J.M., Debyser Z., Baekelandt V. Comparative analysis of adeno-associated viral vector serotypes 1, 2, 5, 7, and 8 in mouse brain. Hum. Gene Ther. 2007, 18:195-206.
-
(2007)
Hum. Gene Ther.
, vol.18
, pp. 195-206
-
-
Taymans, J.M.1
Vandenberghe, L.H.2
Haute, C.V.3
Thiry, I.4
Deroose, C.M.5
Mortelmans, L.6
Wilson, J.M.7
Debyser, Z.8
Baekelandt, V.9
-
126
-
-
0029959555
-
The molecular biology of axon guidance
-
Tessier-Lavigne M., Goodman C.S. The molecular biology of axon guidance. Science 1996, 274:1123-1133.
-
(1996)
Science
, vol.274
, pp. 1123-1133
-
-
Tessier-Lavigne, M.1
Goodman, C.S.2
-
127
-
-
0025977479
-
Intraspinal transplants
-
Tessler A. Intraspinal transplants. Ann. Neurol. 1991, 29:115-123.
-
(1991)
Ann. Neurol.
, vol.29
, pp. 115-123
-
-
Tessler, A.1
-
128
-
-
0030635613
-
Embryonic spinal cord transplants enhance locomotor performance in spinalized newborn rats
-
Tessler A., Fischer I., Giszter S., Himes B.T., Miya D., Mori F., Murray M. Embryonic spinal cord transplants enhance locomotor performance in spinalized newborn rats. Adv. Neurol. 1997, 72:291-303.
-
(1997)
Adv. Neurol.
, vol.72
, pp. 291-303
-
-
Tessler, A.1
Fischer, I.2
Giszter, S.3
Himes, B.T.4
Miya, D.5
Mori, F.6
Murray, M.7
-
129
-
-
0345227300
-
Delayed grafting of BDNF and NT-3 producing fibroblasts into the injured spinal cord stimulates sprouting, partially rescues axotomized red nucleus neurons from loss and atrophy, and provides limited regeneration
-
Tobias C.A., Shumsky J.S., Shibata M., Tuszynski M.H., Fischer I., Tessler A., Murray M. Delayed grafting of BDNF and NT-3 producing fibroblasts into the injured spinal cord stimulates sprouting, partially rescues axotomized red nucleus neurons from loss and atrophy, and provides limited regeneration. Exp. Neurol. 2003, 184:97-113.
-
(2003)
Exp. Neurol.
, vol.184
, pp. 97-113
-
-
Tobias, C.A.1
Shumsky, J.S.2
Shibata, M.3
Tuszynski, M.H.4
Fischer, I.5
Tessler, A.6
Murray, M.7
-
130
-
-
74349088517
-
Efficient transduction of non-human primate motor neurons after intramuscular delivery of recombinant AAV serotype 6
-
Towne C., Schneider B.L., Kieran D., Redmond D.E., Aebischer P. Efficient transduction of non-human primate motor neurons after intramuscular delivery of recombinant AAV serotype 6. Gene Ther. 2010, 17:141-146.
-
(2010)
Gene Ther.
, vol.17
, pp. 141-146
-
-
Towne, C.1
Schneider, B.L.2
Kieran, D.3
Redmond, D.E.4
Aebischer, P.5
-
131
-
-
0035152814
-
Neurotrophins are required for nerve growth during development
-
Tucker K.L., Meyer M., Barde Y.A. Neurotrophins are required for nerve growth during development. Nat. Neurosci. 2001, 4:29-37.
-
(2001)
Nat. Neurosci.
, vol.4
, pp. 29-37
-
-
Tucker, K.L.1
Meyer, M.2
Barde, Y.A.3
-
132
-
-
0030054303
-
Nerve growth factor delivery by gene transfer induces differential outgrowth of sensory, motor, and noradrenergic neurites after adult spinal cord injury
-
Tuszynski M.H., Gabriel K., Gage F.H., Suhr S., Meyer S., Rosetti A. Nerve growth factor delivery by gene transfer induces differential outgrowth of sensory, motor, and noradrenergic neurites after adult spinal cord injury. Exp. Neurol. 1996, 137:157-173.
-
(1996)
Exp. Neurol.
, vol.137
, pp. 157-173
-
-
Tuszynski, M.H.1
Gabriel, K.2
Gage, F.H.3
Suhr, S.4
Meyer, S.5
Rosetti, A.6
-
133
-
-
0037403572
-
NT-3 gene delivery elicits growth of chronically injured corticospinal axons and modestly improves functional deficits after chronic scar resection
-
Tuszynski M.H., Grill R., Jones L.L., Brant A., Blesch A., Low K., Lacroix S., Lu P. NT-3 gene delivery elicits growth of chronically injured corticospinal axons and modestly improves functional deficits after chronic scar resection. Exp. Neurol. 2003, 181:47-56.
-
(2003)
Exp. Neurol.
, vol.181
, pp. 47-56
-
-
Tuszynski, M.H.1
Grill, R.2
Jones, L.L.3
Brant, A.4
Blesch, A.5
Low, K.6
Lacroix, S.7
Lu, P.8
-
134
-
-
84882458528
-
Axonal plasticity and regeneraton in the injured spinal cord
-
Academic Press, London, J.H. Kordower, M.H. Tuszynski (Eds.)
-
Tuszynski M.H., Lu P. Axonal plasticity and regeneraton in the injured spinal cord. CNS regeneration: basic science and clinical advances 2008, 319-337. Academic Press, London. J.H. Kordower, M.H. Tuszynski (Eds.).
-
(2008)
CNS regeneration: basic science and clinical advances
, pp. 319-337
-
-
Tuszynski, M.H.1
Lu, P.2
-
135
-
-
0028218083
-
Fibroblasts genetically modified to produce nerve growth factor induce robust neuritic ingrowth after grafting to the spinal cord
-
Tuszynski M.H., Peterson D.A., Ray J., Baird A., Nakahara Y., Gage F.H. Fibroblasts genetically modified to produce nerve growth factor induce robust neuritic ingrowth after grafting to the spinal cord. Exp. Neurol. 1994, 126:1-14.
-
(1994)
Exp. Neurol.
, vol.126
, pp. 1-14
-
-
Tuszynski, M.H.1
Peterson, D.A.2
Ray, J.3
Baird, A.4
Nakahara, Y.5
Gage, F.H.6
-
136
-
-
21044458854
-
A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease
-
Tuszynski M.H., Thal L., Pay M., Salmon D.P., U U.H.S., Bakay R., Patel P., Blesch A., Vahlsing H.L., Ho G., Tong G., Potkin S.G., Fallon J., Hansen L., Mufson E.J., Kordower J.H., Gall C., Conner J. A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease. Nat Med 2005, 11:551-555.
-
(2005)
Nat Med
, vol.11
, pp. 551-555
-
-
Tuszynski, M.H.1
Thal, L.2
Pay, M.3
Salmon, D.P.4
U, U.H.S.5
Bakay, R.6
Patel, P.7
Blesch, A.8
Vahlsing, H.L.9
Ho, G.10
Tong, G.11
Potkin, S.G.12
Fallon, J.13
Hansen, L.14
Mufson, E.J.15
Kordower, J.H.16
Gall, C.17
Conner, J.18
-
137
-
-
0031919140
-
Grafts of genetically modified Schwann cells to the spinal cord: survival, axon growth, and myelination
-
Tuszynski M.H., Weidner N., McCormack M., Miller I., Powell H., Conner J. Grafts of genetically modified Schwann cells to the spinal cord: survival, axon growth, and myelination. Cell Transplant. 1998, 7:187-196.
-
(1998)
Cell Transplant.
, vol.7
, pp. 187-196
-
-
Tuszynski, M.H.1
Weidner, N.2
McCormack, M.3
Miller, I.4
Powell, H.5
Conner, J.6
-
138
-
-
33745112188
-
BDNF promotes connections of corticospinal neurons onto spared descending interneurons in spinal cord injured rats
-
Vavrek R., Girgis J., Tetzlaff W., Hiebert G.W., Fouad K. BDNF promotes connections of corticospinal neurons onto spared descending interneurons in spinal cord injured rats. Brain 2006, 129:1534-1545.
-
(2006)
Brain
, vol.129
, pp. 1534-1545
-
-
Vavrek, R.1
Girgis, J.2
Tetzlaff, W.3
Hiebert, G.W.4
Fouad, K.5
-
139
-
-
0025968252
-
Plasticity of spinal systems after unilateral lumbosacral dorsal rhizotomy in the adult rat
-
Wang S.D., Goldberger M.E., Murray M. Plasticity of spinal systems after unilateral lumbosacral dorsal rhizotomy in the adult rat. J. Comp. Neurol. 1991, 304:555-568.
-
(1991)
J. Comp. Neurol.
, vol.304
, pp. 555-568
-
-
Wang, S.D.1
Goldberger, M.E.2
Murray, M.3
-
140
-
-
0033232045
-
Nerve growth factor-hypersecreting Schwann cell grafts augment and guide spinal cord axonal growth and remyelinate central nervous system axons in a phenotypically appropriate manner that correlates with expression of L1
-
Weidner N., Blesch A., Grill R.J., Tuszynski M.H. Nerve growth factor-hypersecreting Schwann cell grafts augment and guide spinal cord axonal growth and remyelinate central nervous system axons in a phenotypically appropriate manner that correlates with expression of L1. J. Comp. Neurol. 1999, 413:495-506.
-
(1999)
J. Comp. Neurol.
, vol.413
, pp. 495-506
-
-
Weidner, N.1
Blesch, A.2
Grill, R.J.3
Tuszynski, M.H.4
-
141
-
-
0035853114
-
Spontaneous corticospinal axonal plasticity and functional recovery after adult central nervous system injury
-
Weidner N., Ner A., Salimi N., Tuszynski M.H. Spontaneous corticospinal axonal plasticity and functional recovery after adult central nervous system injury. Proc. Natl Acad. Sci. USA 2001, 98:3513-3518.
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, pp. 3513-3518
-
-
Weidner, N.1
Ner, A.2
Salimi, N.3
Tuszynski, M.H.4
-
142
-
-
0035873540
-
Neurotrophic factors and receptors in the immature and adult spinal cord after mechanical injury or kainic acid
-
Widenfalk J., Lundströmer K., Jubran M., Brene S., Olson L. Neurotrophic factors and receptors in the immature and adult spinal cord after mechanical injury or kainic acid. J. Neurosci. 2001, 21:3457-3475.
-
(2001)
J. Neurosci.
, vol.21
, pp. 3457-3475
-
-
Widenfalk, J.1
Lundströmer, K.2
Jubran, M.3
Brene, S.4
Olson, L.5
-
143
-
-
1142299570
-
Transduction patterns of pseudotyped lentiviral vectors in the nervous system
-
Wong L.F., Azzouz M., Walmsley L.E., Askham Z., Wilkes F.J., Mitrophanous K.A., Kingsman S.M., Mazarakis N.D. Transduction patterns of pseudotyped lentiviral vectors in the nervous system. Mol. Ther. 2004, 9:101-111.
-
(2004)
Mol. Ther.
, vol.9
, pp. 101-111
-
-
Wong, L.F.1
Azzouz, M.2
Walmsley, L.E.3
Askham, Z.4
Wilkes, F.J.5
Mitrophanous, K.A.6
Kingsman, S.M.7
Mazarakis, N.D.8
-
144
-
-
31544480379
-
Retinoic acid receptor beta2 promotes functional regeneration of sensory axons in the spinal cord
-
Wong L.F., Yip P.K., Battaglia A., Grist J., Corcoran J., Maden M., Azzouz M., Kingsman S.M., Kingsman A.J., Mazarakis N.D., McMahon S.B. Retinoic acid receptor beta2 promotes functional regeneration of sensory axons in the spinal cord. Nat. Neurosci. 2006, 9:243-250.
-
(2006)
Nat. Neurosci.
, vol.9
, pp. 243-250
-
-
Wong, L.F.1
Yip, P.K.2
Battaglia, A.3
Grist, J.4
Corcoran, J.5
Maden, M.6
Azzouz, M.7
Kingsman, S.M.8
Kingsman, A.J.9
Mazarakis, N.D.10
McMahon, S.B.11
-
145
-
-
33847422165
-
Actions of neuropoietic cytokines and cyclic AMP in regenerative conditioning of rat primary sensory neurons
-
Wu D., Zhang Y., Bo X., Huang W., Xiao F., Zhang X., Miao T., Magoulas C., Subang M.C., Richardson P.M. Actions of neuropoietic cytokines and cyclic AMP in regenerative conditioning of rat primary sensory neurons. Exp. Neurol. 2006, 204:66-76.
-
(2006)
Exp. Neurol.
, vol.204
, pp. 66-76
-
-
Wu, D.1
Zhang, Y.2
Bo, X.3
Huang, W.4
Xiao, F.5
Zhang, X.6
Miao, T.7
Magoulas, C.8
Subang, M.C.9
Richardson, P.M.10
-
146
-
-
33746874152
-
Adeno-associated virus serotypes: vector toolkit for human gene therapy
-
Wu Z., Asokan A., Samulski R.J. Adeno-associated virus serotypes: vector toolkit for human gene therapy. Mol. Ther. 2006, 14:316-327.
-
(2006)
Mol. Ther.
, vol.14
, pp. 316-327
-
-
Wu, Z.1
Asokan, A.2
Samulski, R.J.3
-
147
-
-
0037062494
-
Identification of gene expression profile of dorsal root ganglion in the rat peripheral axotomy model of neuropathic pain
-
Xiao H.S., Huang Q.H., Zhang F.X., Bao L., Lu Y.J., Guo C., Yang L., Huang W.J., Fu G., Xu S.H., Cheng X.P., Yan Q., Zhu Z.D., Zhang X., Chen Z., Han Z.G., Zhang X. Identification of gene expression profile of dorsal root ganglion in the rat peripheral axotomy model of neuropathic pain. Proc. Natl Acad. Sci. USA 2002, 99:8360-8365.
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 8360-8365
-
-
Xiao, H.S.1
Huang, Q.H.2
Zhang, F.X.3
Bao, L.4
Lu, Y.J.5
Guo, C.6
Yang, L.7
Huang, W.J.8
Fu, G.9
Xu, S.H.10
Cheng, X.P.11
Yan, Q.12
Zhu, Z.D.13
Zhang, X.14
Chen, Z.15
Han, Z.G.16
Zhang, X.17
-
148
-
-
38649122410
-
White matter inhibitors in CNS axon regeneration failure
-
Xie F., Zheng B. White matter inhibitors in CNS axon regeneration failure. Exp. Neurol. 2008, 209:302-312.
-
(2008)
Exp. Neurol.
, vol.209
, pp. 302-312
-
-
Xie, F.1
Zheng, B.2
-
149
-
-
0030989043
-
Bridging Schwann cell transplants promote axonal regeneration from both the rostral and caudal stumps of transected adult rat spinal cord
-
Xu X.M., Chen A., Guenard V., Kleitman N., Bunge M.B. Bridging Schwann cell transplants promote axonal regeneration from both the rostral and caudal stumps of transected adult rat spinal cord. J. Neurocytol. 1997, 26:1-16.
-
(1997)
J. Neurocytol.
, vol.26
, pp. 1-16
-
-
Xu, X.M.1
Chen, A.2
Guenard, V.3
Kleitman, N.4
Bunge, M.B.5
-
150
-
-
0028874907
-
A combination of BDNF and NT-3 promotes supraspinal axonal regeneration into Schwann cell grafts in adult rat thoracic spinal cord
-
Xu X.M., Guenard V., Kleitman N., Aebischer P., Bunge M.B. A combination of BDNF and NT-3 promotes supraspinal axonal regeneration into Schwann cell grafts in adult rat thoracic spinal cord. Exp. Neurol. 1995, 134:261-272.
-
(1995)
Exp. Neurol.
, vol.134
, pp. 261-272
-
-
Xu, X.M.1
Guenard, V.2
Kleitman, N.3
Aebischer, P.4
Bunge, M.B.5
-
151
-
-
0028870347
-
Axonal regeneration into Schwann cell-seeded guidance channels grafted into transected adult rat spinal cord
-
Xu X.M., Guenard V., Kleitman N., Bunge M.B. Axonal regeneration into Schwann cell-seeded guidance channels grafted into transected adult rat spinal cord. J. Comp. Neurol. 1994, 351:145-160.
-
(1994)
J. Comp. Neurol.
, vol.351
, pp. 145-160
-
-
Xu, X.M.1
Guenard, V.2
Kleitman, N.3
Bunge, M.B.4
-
152
-
-
0031013730
-
Treatment of the chronically injured spinal cord with neurotrophic factors can promote axonal regeneration from supraspinal neurons
-
Ye J.H., Houle J.D. Treatment of the chronically injured spinal cord with neurotrophic factors can promote axonal regeneration from supraspinal neurons. Exp. Neurol. 1997, 143:70-81.
-
(1997)
Exp. Neurol.
, vol.143
, pp. 70-81
-
-
Ye, J.H.1
Houle, J.D.2
-
153
-
-
33750213134
-
Lentiviral vector expressing retinoic acid receptor beta2 promotes recovery of function after corticospinal tract injury in the adult rat spinal cord
-
Yip P.K., Wong L.F., Pattinson D., Battaglia A., Grist J., Bradbury E.J., Maden M., McMahon S.B., Mazarakis N.D. Lentiviral vector expressing retinoic acid receptor beta2 promotes recovery of function after corticospinal tract injury in the adult rat spinal cord. Hum. Mol. Genet. 2006, 15:3107-3118.
-
(2006)
Hum. Mol. Genet.
, vol.15
, pp. 3107-3118
-
-
Yip, P.K.1
Wong, L.F.2
Pattinson, D.3
Battaglia, A.4
Grist, J.5
Bradbury, E.J.6
Maden, M.7
McMahon, S.B.8
Mazarakis, N.D.9
-
154
-
-
77954733569
-
Cortical overexpression of neuronal calcium sensor-1 induces functional plasticity in spinal cord following unilateral pyramidal tract injury in rat
-
Yip P.K., Wong L.F., Sears T.A., Yanez-Munoz R.J., McMahon S.B. Cortical overexpression of neuronal calcium sensor-1 induces functional plasticity in spinal cord following unilateral pyramidal tract injury in rat. PLoS Biol. 2010, 8:e1000399.
-
(2010)
PLoS Biol.
, vol.8
-
-
Yip, P.K.1
Wong, L.F.2
Sears, T.A.3
Yanez-Munoz, R.J.4
McMahon, S.B.5
-
155
-
-
0034281370
-
Compensatory sprouting and impulse rerouting after unilateral pyramidal tract lesion in neonatal rats
-
Z'Graggen W.J., Fouad K., Raineteau O., Metz G.A., Schwab M.E., Kartje G.L. Compensatory sprouting and impulse rerouting after unilateral pyramidal tract lesion in neonatal rats. J. Neurosci. 2000, 20:6561-6569.
-
(2000)
J. Neurosci.
, vol.20
, pp. 6561-6569
-
-
Z'Graggen, W.J.1
Fouad, K.2
Raineteau, O.3
Metz, G.A.4
Schwab, M.E.5
Kartje, G.L.6
-
156
-
-
34548731859
-
Lentiviral-mediated expression of polysialic acid in spinal cord and conditioning lesion promote regeneration of sensory axons into spinal cord
-
Zhang Y., Zhang X., Wu D., Verhaagen J., Richardson P.M., Yeh J., Bo X. Lentiviral-mediated expression of polysialic acid in spinal cord and conditioning lesion promote regeneration of sensory axons into spinal cord. Mol. Ther. 2007, 15:1796-1804.
-
(2007)
Mol. Ther.
, vol.15
, pp. 1796-1804
-
-
Zhang, Y.1
Zhang, X.2
Wu, D.3
Verhaagen, J.4
Richardson, P.M.5
Yeh, J.6
Bo, X.7
-
157
-
-
77955411795
-
Enhanced adenoviral gene delivery to motor and dorsal root ganglion neurons following injection into demyelinated peripheral nerves
-
Zhang Y., Zheng Y., Zhang Y.P., Shields L.B., Hu X., Yu P., Burke D.A., Wang H., Jun C., Byers J., Whittemore S.R., Shields C.B. Enhanced adenoviral gene delivery to motor and dorsal root ganglion neurons following injection into demyelinated peripheral nerves. J. Neurosci. Res. 2010, 88:2374-2384.
-
(2010)
J. Neurosci. Res.
, vol.88
, pp. 2374-2384
-
-
Zhang, Y.1
Zheng, Y.2
Zhang, Y.P.3
Shields, L.B.4
Hu, X.5
Yu, P.6
Burke, D.A.7
Wang, H.8
Jun, C.9
Byers, J.10
Whittemore, S.R.11
Shields, C.B.12
-
158
-
-
0037442795
-
Neurotrophin-3 expressed in situ induces axonal plasticity in the adult injured spinal cord
-
Zhou L., Baumgartner B.J., Hill-Felberg S.J., McGowen L.R., Shine H.D. Neurotrophin-3 expressed in situ induces axonal plasticity in the adult injured spinal cord. J. Neurosci. 2003, 23:1424-1431.
-
(2003)
J. Neurosci.
, vol.23
, pp. 1424-1431
-
-
Zhou, L.1
Baumgartner, B.J.2
Hill-Felberg, S.J.3
McGowen, L.R.4
Shine, H.D.5
-
159
-
-
38349065415
-
Targeting axon growth from neuronal transplants along preformed guidance pathways in the adult CNS
-
Ziemba K.S., Chaudhry N., Rabchevsky A.G., Jin Y., Smith G.M. Targeting axon growth from neuronal transplants along preformed guidance pathways in the adult CNS. J. Neurosci. 2008, 28:340-348.
-
(2008)
J. Neurosci.
, vol.28
, pp. 340-348
-
-
Ziemba, K.S.1
Chaudhry, N.2
Rabchevsky, A.G.3
Jin, Y.4
Smith, G.M.5
|