메뉴 건너뛰기




Volumn 102, Issue 7, 2014, Pages 2345-2355

Vascular endothelial growth factor-loaded injectable hydrogel enhances plasticity in the injured spinal cord

Author keywords

alginate; injectable hydrogel; microparticles; nanoparticles; spinal cord; VEGF delivery

Indexed keywords

ALGINATE; CELL PROLIFERATION; ENDOTHELIAL CELLS; NANOPARTICLES; PLASTICITY;

EID: 84901505907     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.34915     Document Type: Article
Times cited : (55)

References (52)
  • 2
    • 78449256874 scopus 로고    scopus 로고
    • Infarct stabilization and cardiac repair with a VEGF-conjugated, injectable hydrogel
    • Li RK
    • Wu J, Zeng F, Huang XP, Chung JC, Konecny F, Weisel RD, Li RK. Infarct stabilization and cardiac repair with a VEGF-conjugated, injectable hydrogel. Biomaterials 2011; 32: 579-586.
    • (2011) Biomaterials , vol.32 , pp. 579-586
    • Wu, J.1    Zeng, F.2    Huang, X.P.3    Chung, J.C.4    Konecny, F.5    Weisel, R.D.6
  • 3
    • 77953959594 scopus 로고    scopus 로고
    • An injectable calcium phosphate-alginate hydrogel-umbilical cord mesenchymal stem cell paste for bone tissue engineering
    • Zhao L, Weir MD, Xu HH,. An injectable calcium phosphate-alginate hydrogel-umbilical cord mesenchymal stem cell paste for bone tissue engineering. Biomaterials 2010; 31: 6502-6510.
    • (2010) Biomaterials , vol.31 , pp. 6502-6510
    • Zhao, L.1    Weir, M.D.2    Xu, H.H.3
  • 5
    • 84856209675 scopus 로고    scopus 로고
    • Polymer and nano-technology applications for repair and reconstruction of the central nervous system
    • Cho Y, Borgens RB,. Polymer and nano-technology applications for repair and reconstruction of the central nervous system. Exp Neurol 2012; 233: 126-144.
    • (2012) Exp Neurol , vol.233 , pp. 126-144
    • Cho, Y.1    Borgens, R.B.2
  • 7
    • 33645899944 scopus 로고    scopus 로고
    • The promotion of oriented axonal regrowth in the injured spinal cord by alginate-based anisotropic capillary hydrogels
    • Faber C, Vroemen M, Bogdahn U, Weidner N
    • Prang P, Muller R, Eljaouhari A, Heckmann K, Kunz W, Weber T, Faber C, Vroemen M, Bogdahn U, Weidner N. The promotion of oriented axonal regrowth in the injured spinal cord by alginate-based anisotropic capillary hydrogels. Biomaterials 2006; 27: 3560-3569.
    • (2006) Biomaterials , vol.27 , pp. 3560-3569
    • Prang, P.1    Muller, R.2    Eljaouhari, A.3    Heckmann, K.4    Kunz, W.5    Weber, T.6
  • 8
    • 19944433307 scopus 로고    scopus 로고
    • Alginate encapsulated BDNF-producing fibroblast grafts permit recovery of function after spinal cord injury in the absence of immune suppression
    • Wheatley MA, Fischer I, Tessler A, Murray M
    • Tobias CA, Han SS, Shumsky JS, Kim D, Tumolo M, Dhoot NO, Wheatley MA, Fischer I, Tessler A, Murray M. Alginate encapsulated BDNF-producing fibroblast grafts permit recovery of function after spinal cord injury in the absence of immune suppression. J Neurotrauma 2005; 22: 138-156.
    • (2005) J Neurotrauma , vol.22 , pp. 138-156
    • Tobias, C.A.1    Han, S.S.2    Shumsky, J.S.3    Kim, D.4    Tumolo, M.5    Dhoot, N.O.6
  • 9
    • 2342527151 scopus 로고    scopus 로고
    • Alginate enhances elongation of early regenerating axons in spinal cord of young rats
    • Ohta M, Wu S, Suzuki K, Ide C
    • Kataoka K, Suzuki Y, Kitada M, Hashimoto T, Chou H, Bai H, Ohta M, Wu S, Suzuki K, Ide C. Alginate enhances elongation of early regenerating axons in spinal cord of young rats. Tissue Eng 2004; 10: 493-504.
    • (2004) Tissue Eng , vol.10 , pp. 493-504
    • Kataoka, K.1    Suzuki, Y.2    Kitada, M.3    Hashimoto, T.4    Chou, H.5    Bai, H.6
  • 10
    • 0035079949 scopus 로고    scopus 로고
    • Grafting of encapsulated BDNF-producing fibroblasts into the injured spinal cord without immune suppression in adult rats
    • Tobias CA, Dhoot NO, Wheatley MA, Tessler A, Murray M, Fischer I,. Grafting of encapsulated BDNF-producing fibroblasts into the injured spinal cord without immune suppression in adult rats. J Neurotrauma 2001; 18: 287-301.
    • (2001) J Neurotrauma , vol.18 , pp. 287-301
    • Tobias, C.A.1    Dhoot, N.O.2    Wheatley, M.A.3    Tessler, A.4    Murray, M.5    Fischer, I.6
  • 11
    • 67349266311 scopus 로고    scopus 로고
    • Preparation and characterization of an injectable composite
    • Tan R, Niu X, Gan S, Feng Q,. Preparation and characterization of an injectable composite. J Mater Sci Mater Med 2009; 20: 1245-1253.
    • (2009) J Mater Sci Mater Med , vol.20 , pp. 1245-1253
    • Tan, R.1    Niu, X.2    Gan, S.3    Feng, Q.4
  • 12
    • 77956240458 scopus 로고    scopus 로고
    • Fetal allogeneic umbilical cord cell transplantation improves motor function in spinal cord-injured rats
    • Altinors MN
    • Erdogan B, Bavbek M, Sahin IF, Caner H, Ozen O, Denkbas EB, Altinors MN. Fetal allogeneic umbilical cord cell transplantation improves motor function in spinal cord-injured rats. Turk Neurosurg 2010; 20: 286-294.
    • (2010) Turk Neurosurg , vol.20 , pp. 286-294
    • Erdogan, B.1    Bavbek, M.2    Sahin, I.F.3    Caner, H.4    Ozen, O.5    Denkbas, E.B.6
  • 13
    • 0033772764 scopus 로고    scopus 로고
    • Fibrinogen binds to integrin alpha(5)beta(1) via the carboxyl-terminal RGD site of the Aalpha-chain
    • Suehiro K, Mizuguchi J, Nishiyama K, Iwanaga S, Farrell DH, Ohtaki S,. Fibrinogen binds to integrin alpha(5)beta(1) via the carboxyl-terminal RGD site of the Aalpha-chain. J Biochem 2000; 128: 705-710.
    • (2000) J Biochem , vol.128 , pp. 705-710
    • Suehiro, K.1    Mizuguchi, J.2    Nishiyama, K.3    Iwanaga, S.4    Farrell, D.H.5    Ohtaki, S.6
  • 14
    • 75149178099 scopus 로고    scopus 로고
    • The biocompatibility of PluronicF127 fibrinogen-based hydrogels
    • Shachaf Y, Gonen-Wadmany M, Seliktar D,. The biocompatibility of PluronicF127 fibrinogen-based hydrogels. Biomaterials 2010; 31: 2836-2847.
    • (2010) Biomaterials , vol.31 , pp. 2836-2847
    • Shachaf, Y.1    Gonen-Wadmany, M.2    Seliktar, D.3
  • 15
    • 77949659351 scopus 로고    scopus 로고
    • The use of injectable forms of fibrin and fibronectin to support axonal ingrowth after spinal cord injury
    • King VR, Alovskaya A, Wei DY, Brown RA, Priestley JV,. The use of injectable forms of fibrin and fibronectin to support axonal ingrowth after spinal cord injury. Biomaterials 2010; 31: 4447-4456.
    • (2010) Biomaterials , vol.31 , pp. 4447-4456
    • King, V.R.1    Alovskaya, A.2    Wei, D.Y.3    Brown, R.A.4    Priestley, J.V.5
  • 16
    • 4644234505 scopus 로고    scopus 로고
    • VEGF: Once regarded as a specific angiogenic factor, now implicated in neuroprotection
    • Storkebaum E, Lambrechts D, Carmeliet P,. VEGF: Once regarded as a specific angiogenic factor, now implicated in neuroprotection. Bioessays 2004; 26: 943-954.
    • (2004) Bioessays , vol.26 , pp. 943-954
    • Storkebaum, E.1    Lambrechts, D.2    Carmeliet, P.3
  • 18
    • 22444447946 scopus 로고    scopus 로고
    • Common mechanisms of nerve and blood vessel wiring
    • Carmeliet P, Tessier-Lavigne M,. Common mechanisms of nerve and blood vessel wiring. Nature 2005; 436: 193-200.
    • (2005) Nature , vol.436 , pp. 193-200
    • Carmeliet, P.1    Tessier-Lavigne, M.2
  • 19
    • 79953829608 scopus 로고    scopus 로고
    • Effect of vascular endothelial growth factor treatment in experimental traumatic spinal cord injury: In vivo longitudinal assessment
    • Sundberg LM, Herrera JJ, Narayana PA,. Effect of vascular endothelial growth factor treatment in experimental traumatic spinal cord injury: In vivo longitudinal assessment. J Neurotrauma 2011; 28: 565-578.
    • (2011) J Neurotrauma , vol.28 , pp. 565-578
    • Sundberg, L.M.1    Herrera, J.J.2    Narayana, P.A.3
  • 20
    • 77958160282 scopus 로고    scopus 로고
    • Repetitive intrathecal VEGF(165) treatment has limited therapeutic effects after spinal cord injury in the rat
    • Marcus MA, Steinbusch HW, van Kleef M, Patijn J, Deumens R
    • van Neerven S, Joosten EA, Brook GA, Lambert CA, Mey J, Weis J, Marcus MA, Steinbusch HW, van Kleef M, Patijn J, Deumens R. Repetitive intrathecal VEGF(165) treatment has limited therapeutic effects after spinal cord injury in the rat. J Neurotrauma 2010; 27: 1781-1791.
    • (2010) J Neurotrauma , vol.27 , pp. 1781-1791
    • Van Neerven, S.1    Joosten, E.A.2    Brook, G.A.3    Lambert, C.A.4    Mey, J.5    Weis, J.6
  • 22
    • 70349695703 scopus 로고    scopus 로고
    • Targeting VEGF-encapsulated immunoliposomes to MI heart improves vascularity and cardiac function
    • Crabbe DL, Kiani MF
    • Scott RC, Rosano JM, Ivanov Z, Wang B, Chong PL, Issekutz AC, Crabbe DL, Kiani MF. Targeting VEGF-encapsulated immunoliposomes to MI heart improves vascularity and cardiac function. FASEB J 2009.
    • (2009) FASEB J
    • Scott, R.C.1    Rosano, J.M.2    Ivanov, Z.3    Wang, B.4    Chong, P.L.5    Issekutz, A.C.6
  • 23
    • 42249103434 scopus 로고    scopus 로고
    • The effect of sustained delivery of vascular endothelial growth factor on angiogenesis in tissue-engineered intestine
    • Vacanti JP, Whang EE
    • Rocha FG, Sundback CA, Krebs NJ, Leach JK, Mooney DJ, Ashley SW, Vacanti JP, Whang EE. The effect of sustained delivery of vascular endothelial growth factor on angiogenesis in tissue-engineered intestine. Biomaterials 2008; 29: 2884-2890.
    • (2008) Biomaterials , vol.29 , pp. 2884-2890
    • Rocha, F.G.1    Sundback, C.A.2    Krebs, N.J.3    Leach, J.K.4    Mooney, D.J.5    Ashley, S.W.6
  • 24
    • 34249898340 scopus 로고    scopus 로고
    • Polyelectrolyte complexes stabilize and controllably release vascular endothelial growth factor
    • Huang M, Vitharana SN, Peek LJ, Coop T, Berkland C,. Polyelectrolyte complexes stabilize and controllably release vascular endothelial growth factor. Biomacromolecules 2007; 8: 1607-1614.
    • (2007) Biomacromolecules , vol.8 , pp. 1607-1614
    • Huang, M.1    Vitharana, S.N.2    Peek, L.J.3    Coop, T.4    Berkland, C.5
  • 25
    • 79955824571 scopus 로고    scopus 로고
    • Sustained release of VEGF through PLGA microparticles improves vasculogenesis and tissue remodeling in an acute myocardial ischemia-reperfusion model
    • Mazo M, Tamayo E, Jauquicoa C, Ortiz-de-Solorzano C, Prosper F, Blanco-Prieto MJ
    • Formiga FR, Pelacho B, Garbayo E, Abizanda G, Gavira JJ, Simon-Yarza T, Mazo M, Tamayo E, Jauquicoa C, Ortiz-de-Solorzano C, Prosper F, Blanco-Prieto MJ. Sustained release of VEGF through PLGA microparticles improves vasculogenesis and tissue remodeling in an acute myocardial ischemia-reperfusion model. J Control Release 2010; 147: 30-37.
    • (2010) J Control Release , vol.147 , pp. 30-37
    • Formiga, F.R.1    Pelacho, B.2    Garbayo, E.3    Abizanda, G.4    Gavira, J.J.5    Simon-Yarza, T.6
  • 27
    • 60549089022 scopus 로고    scopus 로고
    • Local gene delivery from ECM-coated poly(lactide-co-glycolide) multiple channel bridges after spinal cord injury
    • De Laporte L, Lei Yan A, Shea LD,. Local gene delivery from ECM-coated poly(lactide-co-glycolide) multiple channel bridges after spinal cord injury. Biomaterials 2009; 30: 2361-2368.
    • (2009) Biomaterials , vol.30 , pp. 2361-2368
    • De Laporte, L.1    Lei Yan, A.2    Shea, L.D.3
  • 29
    • 84872855487 scopus 로고    scopus 로고
    • Hexafluorobenzene in comparison with perfluoro-15-crown-5-ether for repeated monitoring of oxygenation using 19F MRI in a mouse model
    • Mignion L, Magat J, Schakman O, Marbaix E, Gallez B, Jordan BF,. Hexafluorobenzene in comparison with perfluoro-15-crown-5-ether for repeated monitoring of oxygenation using 19F MRI in a mouse model. Magn Reson Med 2013; 69: 248-254.
    • (2013) Magn Reson Med , vol.69 , pp. 248-254
    • Mignion, L.1    Magat, J.2    Schakman, O.3    Marbaix, E.4    Gallez, B.5    Jordan, B.F.6
  • 30
    • 73549086992 scopus 로고    scopus 로고
    • Fibrin-based tissue engineering scaffolds enhance neural fiber sprouting and delay the accumulation of reactive astrocytes at the lesion in a subacute model of spinal cord injury
    • Johnson PJ, Parker SR, Sakiyama-Elbert SE,. Fibrin-based tissue engineering scaffolds enhance neural fiber sprouting and delay the accumulation of reactive astrocytes at the lesion in a subacute model of spinal cord injury. J Biomed Mater Res A 2010; 92: 152-163.
    • (2010) J Biomed Mater Res A , vol.92 , pp. 152-163
    • Johnson, P.J.1    Parker, S.R.2    Sakiyama-Elbert, S.E.3
  • 32
    • 85047694286 scopus 로고    scopus 로고
    • VEGF: A critical player in neurodegeneration
    • Storkebaum E, Carmeliet P,. VEGF: A critical player in neurodegeneration. J Clin Invest 2004; 113: 14-18.
    • (2004) J Clin Invest , vol.113 , pp. 14-18
    • Storkebaum, E.1    Carmeliet, P.2
  • 33
    • 0036445830 scopus 로고    scopus 로고
    • Vascular and neuronal effects of VEGF in the nervous system: Implications for neurological disorders
    • Carmeliet P, Storkebaum E,. Vascular and neuronal effects of VEGF in the nervous system: Implications for neurological disorders. Semin Cell Dev Biol 2002; 13: 39-53.
    • (2002) Semin Cell Dev Biol , vol.13 , pp. 39-53
    • Carmeliet, P.1    Storkebaum, E.2
  • 34
    • 0033565417 scopus 로고    scopus 로고
    • Vascular endothelial growth factor has neurotrophic activity and stimulates axonal outgrowth, enhancing cell survival and Schwann cell proliferation in the peripheral nervous system
    • Sondell M, Lundborg G, Kanje M,. Vascular endothelial growth factor has neurotrophic activity and stimulates axonal outgrowth, enhancing cell survival and Schwann cell proliferation in the peripheral nervous system. J Neurosci 1999; 19: 5731-5740.
    • (1999) J Neurosci , vol.19 , pp. 5731-5740
    • Sondell, M.1    Lundborg, G.2    Kanje, M.3
  • 35
    • 77950688796 scopus 로고    scopus 로고
    • Characterization of poly(ethylene glycol) gels with added collagen for neural tissue engineering
    • Scott R, Marquardt L, Willits RK,. Characterization of poly(ethylene glycol) gels with added collagen for neural tissue engineering. J Biomed Mater Res Part A 2010; 93A: 817-823.
    • (2010) J Biomed Mater Res Part A , vol.93 A , pp. 817-823
    • Scott, R.1    Marquardt, L.2    Willits, R.K.3
  • 36
    • 56249141782 scopus 로고    scopus 로고
    • Rheological properties of the tissues of the central nervous system: A review
    • Cheng S, Clarke EC, Bilston LE,. Rheological properties of the tissues of the central nervous system: A review. Med Eng Phys 2008; 30: 1318-1337.
    • (2008) Med Eng Phys , vol.30 , pp. 1318-1337
    • Cheng, S.1    Clarke, E.C.2    Bilston, L.E.3
  • 37
    • 77953825835 scopus 로고    scopus 로고
    • In vivo selection of biocompatible alginates for islet encapsulation and subcutaneous transplantation
    • Leveque P, Gallez B, Gianello P, Dufrane D
    • Veriter S, Mergen J, Goebbels RM, Aouassar N, Gregoire C, Jordan B, Leveque P, Gallez B, Gianello P, Dufrane D. In vivo selection of biocompatible alginates for islet encapsulation and subcutaneous transplantation. Tissue Eng Part A 2010; 16: 1503-1513.
    • (2010) Tissue Eng Part A , vol.16 , pp. 1503-1513
    • Veriter, S.1    Mergen, J.2    Goebbels, R.M.3    Aouassar, N.4    Gregoire, C.5    Jordan, B.6
  • 38
    • 77952134687 scopus 로고    scopus 로고
    • Cell encapsulation using biopolymer gels for regenerative medicine
    • Hunt NC, Grover LM,. Cell encapsulation using biopolymer gels for regenerative medicine. Biotechnol Lett 2010; 32: 733-742.
    • (2010) Biotechnol Lett , vol.32 , pp. 733-742
    • Hunt, N.C.1    Grover, L.M.2
  • 39
    • 0032941232 scopus 로고    scopus 로고
    • Alginate hydrogels as synthetic extracellular matrix materials
    • Rowley JA, Madlambayan G, Mooney DJ,. Alginate hydrogels as synthetic extracellular matrix materials. Biomaterials 1999; 20: 45-53.
    • (1999) Biomaterials , vol.20 , pp. 45-53
    • Rowley, J.A.1    Madlambayan, G.2    Mooney, D.J.3
  • 41
    • 84863007615 scopus 로고    scopus 로고
    • Layer-shaped alginate hydrogels enhance the biological performance of human adipose-derived stem cells
    • Galateanu B, Dimonie D, Vasile E, Nae S, Cimpean A, Costache M,. Layer-shaped alginate hydrogels enhance the biological performance of human adipose-derived stem cells. BMC Biotechnol 2012; 12: 35.
    • (2012) BMC Biotechnol , vol.12 , pp. 35
    • Galateanu, B.1    Dimonie, D.2    Vasile, E.3    Nae, S.4    Cimpean, A.5    Costache, M.6
  • 42
    • 84860754395 scopus 로고    scopus 로고
    • Stem cell-derived extracellular matrix enables survival and multilineage differentiation within superporous hydrogels
    • Köllmer M, Keskar V, Hauk TG, Collins JM, Russell B, Gemeinhart RA,. Stem cell-derived extracellular matrix enables survival and multilineage differentiation within superporous hydrogels. Biomacromolecules 2012; 13: 963-973.
    • (2012) Biomacromolecules , vol.13 , pp. 963-973
    • Köllmer, M.1    Keskar, V.2    Hauk, T.G.3    Collins, J.M.4    Russell, B.5    Gemeinhart, R.A.6
  • 43
    • 9344240796 scopus 로고    scopus 로고
    • Adhesion and growth of bone marrow stromal cells on modified alginate hydrogels
    • Lawson MA, Barralet JE, Wang L, Shelton RM, Triffitt JT,. Adhesion and growth of bone marrow stromal cells on modified alginate hydrogels. Tissue Eng 2004; 10: 1480-1491.
    • (2004) Tissue Eng , vol.10 , pp. 1480-1491
    • Lawson, M.A.1    Barralet, J.E.2    Wang, L.3    Shelton, R.M.4    Triffitt, J.T.5
  • 44
    • 84856489292 scopus 로고    scopus 로고
    • Injectable hydrogel materials for spinal cord regeneration: A review
    • Macaya D, Spector M,. Injectable hydrogel materials for spinal cord regeneration: A review. Biomed Mater 2012; 7: 012001.
    • (2012) Biomed Mater , vol.7 , pp. 012001
    • Macaya, D.1    Spector, M.2
  • 45
    • 84855408702 scopus 로고    scopus 로고
    • Novel soft alginate hydrogel strongly supports neurite growth and protects neurons against oxidative stress
    • Matyash M, Despang F, Mandal R, Fiore D, Gelinsky M, Ikonomidou C,. Novel soft alginate hydrogel strongly supports neurite growth and protects neurons against oxidative stress. Tissue Eng Part A 2012; 18: 55-66.
    • (2012) Tissue Eng Part A , vol.18 , pp. 55-66
    • Matyash, M.1    Despang, F.2    Mandal, R.3    Fiore, D.4    Gelinsky, M.5    Ikonomidou, C.6
  • 46
    • 79960358602 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and fibroblast growth factor 2 delivery from spinal cord bridges to enhance angiogenesis following injury
    • Preat V, Shea LD
    • De Laporte L, des Rieux A, Tuinstra HM, Zelivyanskaya ML, De Clerck NM, Postnov AA, Preat V, Shea LD. Vascular endothelial growth factor and fibroblast growth factor 2 delivery from spinal cord bridges to enhance angiogenesis following injury. J Biomed Mater Res A 2011; 98: 372-382.
    • (2011) J Biomed Mater Res A , vol.98 , pp. 372-382
    • De Laporte, L.1    Des Rieux, A.2    Tuinstra, H.M.3    Zelivyanskaya, M.L.4    De Clerck, N.M.5    Postnov, A.A.6
  • 47
    • 80052379936 scopus 로고    scopus 로고
    • Enhancement of sciatic nerve regeneration after vascular endothelial growth factor (VEGF) gene therapy
    • Langone F, Lora S, Melo PA, Borojevic R, Han SW, Martinez AM
    • Pereira Lopes FR, Lisboa BC, Frattini F, Almeida FM, Tomaz MA, Matsumoto PK, Langone F, Lora S, Melo PA, Borojevic R, Han SW, Martinez AM. Enhancement of sciatic nerve regeneration after vascular endothelial growth factor (VEGF) gene therapy. Neuropathol Appl Neurobiol 2011; 37: 600-612.
    • (2011) Neuropathol Appl Neurobiol , vol.37 , pp. 600-612
    • Pereira Lopes, F.R.1    Lisboa, B.C.2    Frattini, F.3    Almeida, F.M.4    Tomaz, M.A.5    Matsumoto, P.K.6
  • 48
    • 84864376057 scopus 로고    scopus 로고
    • Naringin treatment improves functional recovery by increasing BDNF and VEGF expression, inhibiting neuronal apoptosis after spinal cord injury
    • Han X, Liu Z
    • Rong W, Wang J, Liu X, Jiang L, Wei F, Hu X, Han X, Liu Z. Naringin treatment improves functional recovery by increasing BDNF and VEGF expression, inhibiting neuronal apoptosis after spinal cord injury. Neurochem Res 2012; 37: 1615-1623.
    • (2012) Neurochem Res , vol.37 , pp. 1615-1623
    • Rong, W.1    Wang, J.2    Liu, X.3    Jiang, L.4    Wei, F.5    Hu, X.6
  • 49
    • 84863094387 scopus 로고    scopus 로고
    • Simvastatin mobilizes bone marrow stromal cells migrating to injured areas and promotes functional recovery after spinal cord injury in the rat
    • Han X, Yang N, Cui Y, Xu Y, Dang G, Song C,. Simvastatin mobilizes bone marrow stromal cells migrating to injured areas and promotes functional recovery after spinal cord injury in the rat. Neurosci Lett 2012; 521: 136-141.
    • (2012) Neurosci Lett , vol.521 , pp. 136-141
    • Han, X.1    Yang, N.2    Cui, Y.3    Xu, Y.4    Dang, G.5    Song, C.6
  • 50
    • 0042133340 scopus 로고    scopus 로고
    • Vascular endothelial growth factor improves functional outcome and decreases secondary degeneration in experimental spinal cord contusion injury
    • Olson L
    • Widenfalk J, Lipson A, Jubran M, Hofstetter C, Ebendal T, Cao Y, Olson L. Vascular endothelial growth factor improves functional outcome and decreases secondary degeneration in experimental spinal cord contusion injury. Neuroscience 2003; 120: 951-960.
    • (2003) Neuroscience , vol.120 , pp. 951-960
    • Widenfalk, J.1    Lipson, A.2    Jubran, M.3    Hofstetter, C.4    Ebendal, T.5    Cao, Y.6
  • 51
    • 84863029363 scopus 로고    scopus 로고
    • An in vivo characterization of trophic factor production following neural precursor cell or bone marrow stromal cell transplantation for spinal cord injury
    • Hawryluk GW, Mothe A, Wang J, Wang S, Tator C, Fehlings MG,. An in vivo characterization of trophic factor production following neural precursor cell or bone marrow stromal cell transplantation for spinal cord injury. Stem Cells Dev 2012; 21: 2222-2238.
    • (2012) Stem Cells Dev , vol.21 , pp. 2222-2238
    • Hawryluk, G.W.1    Mothe, A.2    Wang, J.3    Wang, S.4    Tator, C.5    Fehlings, M.G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.