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Volumn 169, Issue 2, 2009, Pages 183-199

Current tissue engineering and novel therapeutic approaches to axonal regeneration following spinal cord injury using polymer scaffolds

Author keywords

Axonal regeneration; Neurotrophins; Polymer scaffold; Spinal cord injury; Tissue engineering

Indexed keywords

AGAROSE; ALGINIC ACID; CHITOSAN; COLLAGEN TYPE 1; FIBRIN; FIBRONECTIN; HYALURONIC ACID; MICROSPHERE; NANOSHELL; NANOSPHERE; NEUROTROPHIN; POLYMER; TISSUE SCAFFOLD;

EID: 72049112040     PISSN: 15699048     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.resp.2009.08.015     Document Type: Review
Times cited : (180)

References (167)
  • 2
    • 0035105945 scopus 로고    scopus 로고
    • Agarose gel stiffness determines rate of DRG neurite extension in 3D cultures
    • Balgude A.P., Yu X., Szymanski A., and Bellamkonda R.V. Agarose gel stiffness determines rate of DRG neurite extension in 3D cultures. Biomaterials 22 (2001) 1077-1084
    • (2001) Biomaterials , vol.22 , pp. 1077-1084
    • Balgude, A.P.1    Yu, X.2    Szymanski, A.3    Bellamkonda, R.V.4
  • 3
    • 0035122596 scopus 로고    scopus 로고
    • Neurotrophins BDNF and NT-3 promote axonal re-entry into the distal host spinal cord through Schwann cell-seeded mini-channels
    • Bamber N.I., Li H., Lu X., Oudega M., Aebischer P., and Xu X.M. Neurotrophins BDNF and NT-3 promote axonal re-entry into the distal host spinal cord through Schwann cell-seeded mini-channels. Eur. J. Neurosci. 13 (2001) 257-268
    • (2001) Eur. J. Neurosci. , vol.13 , pp. 257-268
    • Bamber, N.I.1    Li, H.2    Lu, X.3    Oudega, M.4    Aebischer, P.5    Xu, X.M.6
  • 4
    • 33646468919 scopus 로고    scopus 로고
    • Peripheral nerve regeneration: an opinion on channels, scaffolds and anisotropy
    • Bellamkonda R. Peripheral nerve regeneration: an opinion on channels, scaffolds and anisotropy. Biomaterials 27 (2006) 3515-3518
    • (2006) Biomaterials , vol.27 , pp. 3515-3518
    • Bellamkonda, R.1
  • 6
    • 0033997784 scopus 로고    scopus 로고
    • Development of microspheres for neurological disorders: from basics to clinical applications
    • Benoit J.P., Faisant N., Venier-Julienne M.C., and Menei P. Development of microspheres for neurological disorders: from basics to clinical applications. J. Control Release 65 (2000) 285-296
    • (2000) J. Control Release , vol.65 , pp. 285-296
    • Benoit, J.P.1    Faisant, N.2    Venier-Julienne, M.C.3    Menei, P.4
  • 8
    • 58149512333 scopus 로고    scopus 로고
    • Spinal cord injury: plasticity, regeneration and the challenge of translational drug development
    • Blesch A., and Tuszynski M.H. Spinal cord injury: plasticity, regeneration and the challenge of translational drug development. Trends Neurosci. 32 (2009) 41-47
    • (2009) Trends Neurosci. , vol.32 , pp. 41-47
    • Blesch, A.1    Tuszynski, M.H.2
  • 9
    • 0037466249 scopus 로고    scopus 로고
    • Adeno-associated viral vector-mediated neurotrophin gene transfer in the injured adult rat spinal cord improves hind-limb function
    • Blits B., Oudega M., Boer G.J., Bartlett Bunge M., and Verhaagen J. Adeno-associated viral vector-mediated neurotrophin gene transfer in the injured adult rat spinal cord improves hind-limb function. Neuroscience 118 (2003) 271-281
    • (2003) Neuroscience , vol.118 , pp. 271-281
    • Blits, B.1    Oudega, M.2    Boer, G.J.3    Bartlett Bunge, M.4    Verhaagen, J.5
  • 10
    • 0036215085 scopus 로고    scopus 로고
    • Imaging in chronic spinal cord injury-indications and benefits
    • Bodley R. Imaging in chronic spinal cord injury-indications and benefits. Eur. J. Radiol. 42 (2002) 135-153
    • (2002) Eur. J. Radiol. , vol.42 , pp. 135-153
    • Bodley, R.1
  • 11
    • 0036339116 scopus 로고    scopus 로고
    • Behavioural recovery from spinal cord injury following application of polyethylene glycol
    • Borgens R.B., Shi R., and Bohnert D. Behavioural recovery from spinal cord injury following application of polyethylene glycol. J. Exp. Neurol. 205 (2002) 1-12
    • (2002) J. Exp. Neurol. , vol.205 , pp. 1-12
    • Borgens, R.B.1    Shi, R.2    Bohnert, D.3
  • 13
    • 34147114353 scopus 로고    scopus 로고
    • Photo-patterning of porous hydrogels for tissue engineering
    • Bryant S.J., Cuy J.L., Hauch K.D., and Ratner B.D. Photo-patterning of porous hydrogels for tissue engineering. Biomaterials 28 (2007) 2978-2986
    • (2007) Biomaterials , vol.28 , pp. 2978-2986
    • Bryant, S.J.1    Cuy, J.L.2    Hauch, K.D.3    Ratner, B.D.4
  • 14
    • 0035148507 scopus 로고    scopus 로고
    • Pluripotent stem cells engrafted into the normal or lesioned adult rat spinal cord are restricted to a glial lineage
    • Cao Q.L., Zhang Y.P., Howard R.M., Walters W.M., Tsoulfas P., and Whittemore S.R. Pluripotent stem cells engrafted into the normal or lesioned adult rat spinal cord are restricted to a glial lineage. Exp Neurol. 167 (2001) 48-58
    • (2001) Exp Neurol. , vol.167 , pp. 48-58
    • Cao, Q.L.1    Zhang, Y.P.2    Howard, R.M.3    Walters, W.M.4    Tsoulfas, P.5    Whittemore, S.R.6
  • 15
    • 0035925694 scopus 로고    scopus 로고
    • Defining the concentration gradient of nerve growth factor for guided neurite outgrowth
    • Cao X., and Shoichet M.S. Defining the concentration gradient of nerve growth factor for guided neurite outgrowth. Neuroscience 103 (2001) 831-840
    • (2001) Neuroscience , vol.103 , pp. 831-840
    • Cao, X.1    Shoichet, M.S.2
  • 16
    • 33746667836 scopus 로고    scopus 로고
    • Mechanical and morphological characterization of homogeneous and bilayered poly(2-hydroxyethyl methacrylate) scaffolds for use in CNS nerve regeneration
    • Carone T.W., and Hasenwinkel J.M. Mechanical and morphological characterization of homogeneous and bilayered poly(2-hydroxyethyl methacrylate) scaffolds for use in CNS nerve regeneration. J. Biomed. Mater. Res. B App. l Biomater. 78 (2006) 274-282
    • (2006) J. Biomed. Mater. Res. B App. l Biomater. , vol.78 , pp. 274-282
    • Carone, T.W.1    Hasenwinkel, J.M.2
  • 18
    • 0029985953 scopus 로고    scopus 로고
    • Methylprednisolone administration improves axonal regeneration into Schwann cell grafts in transected adult rat thoracic spinal cord
    • Chen A., Xu X.M., Kleitman N., and Bunge M.B. Methylprednisolone administration improves axonal regeneration into Schwann cell grafts in transected adult rat thoracic spinal cord. Exp. Neurol. 138 (1996) 261-276
    • (1996) Exp. Neurol. , vol.138 , pp. 261-276
    • Chen, A.1    Xu, X.M.2    Kleitman, N.3    Bunge, M.B.4
  • 19
    • 0038078504 scopus 로고    scopus 로고
    • Study on physical properties and nerve cell affinity of composite films from chitosan and gelatin solutions
    • Cheng M., Deng J., Yang F., Gong Y., Zhao N., and Zhang X. Study on physical properties and nerve cell affinity of composite films from chitosan and gelatin solutions. Biomaterials 24 (2003) 2871-2880
    • (2003) Biomaterials , vol.24 , pp. 2871-2880
    • Cheng, M.1    Deng, J.2    Yang, F.3    Gong, Y.4    Zhao, N.5    Zhang, X.6
  • 20
    • 0034714306 scopus 로고    scopus 로고
    • Characterization and intraspinal grafting of EGF/bFGF-dependent neurospheres derived from embryonic rat spinal cord
    • Chow S.Y., Moul J., Tobias C.A., Himes B.T., Liu Y., Obrocka M., Hodge L., Tessler A., and Fischer I. Characterization and intraspinal grafting of EGF/bFGF-dependent neurospheres derived from embryonic rat spinal cord. Brain Res. 874 (2000) 86-106
    • (2000) Brain Res. , vol.874 , pp. 86-106
    • Chow, S.Y.1    Moul, J.2    Tobias, C.A.3    Himes, B.T.4    Liu, Y.5    Obrocka, M.6    Hodge, L.7    Tessler, A.8    Fischer, I.9
  • 22
    • 39749107214 scopus 로고    scopus 로고
    • Spatial distribution and acute anti-inflammatory effects of Methylprednisolone after sustained local delivery to the contused spinal cord
    • Chvatal S.A., Kim Y.T., Bratt-Leal A.M., Lee H., and Bellamkonda R.V. Spatial distribution and acute anti-inflammatory effects of Methylprednisolone after sustained local delivery to the contused spinal cord. Biomaterials 29 (2008) 1967-1975
    • (2008) Biomaterials , vol.29 , pp. 1967-1975
    • Chvatal, S.A.1    Kim, Y.T.2    Bratt-Leal, A.M.3    Lee, H.4    Bellamkonda, R.V.5
  • 26
    • 60549089022 scopus 로고    scopus 로고
    • Local gene delivery from ECM-coated poly(lactide-co-glycolide) multiple channel bridges after spinal cord injury
    • De Laporte L., Lei Yan A., and Shea L.D. Local gene delivery from ECM-coated poly(lactide-co-glycolide) multiple channel bridges after spinal cord injury. Biomaterials 30 (2009) 2361-2368
    • (2009) Biomaterials , vol.30 , pp. 2361-2368
    • De Laporte, L.1    Lei Yan, A.2    Shea, L.D.3
  • 30
    • 73349118507 scopus 로고    scopus 로고
    • Collagen I-Matrigel scaffolds for enhanced Schwann cell survival and control of 3D cell morphology
    • (Epub February 20, 2009)
    • Dewitt D.G., Kaszuba S.N., Thompson D.M., and Stegemann J.P. Collagen I-Matrigel scaffolds for enhanced Schwann cell survival and control of 3D cell morphology. Tissue Eng. A (2009) (Epub February 20, 2009)
    • (2009) Tissue Eng. A
    • Dewitt, D.G.1    Kaszuba, S.N.2    Thompson, D.M.3    Stegemann, J.P.4
  • 31
    • 27944497333 scopus 로고    scopus 로고
    • Tissue cells feel and respond to the stiffness of their substrate
    • Discher D.E., Janmey P., and Wang Y.L. Tissue cells feel and respond to the stiffness of their substrate. Science 310 (2005) 1139-1143
    • (2005) Science , vol.310 , pp. 1139-1143
    • Discher, D.E.1    Janmey, P.2    Wang, Y.L.3
  • 32
    • 34248187020 scopus 로고    scopus 로고
    • Effects of polyethylene glycol and magnesium sulfate administration on clinically relevant neurological outcomes after spinal cord injury in the rat
    • Ditor D.S., John S.M., Roy J., Marx J.C., Kittmer C., and Weaver L.C. Effects of polyethylene glycol and magnesium sulfate administration on clinically relevant neurological outcomes after spinal cord injury in the rat. J. Neurosci. Res. 85 (2007) 1458-1467
    • (2007) J. Neurosci. Res. , vol.85 , pp. 1458-1467
    • Ditor, D.S.1    John, S.M.2    Roy, J.3    Marx, J.C.4    Kittmer, C.5    Weaver, L.C.6
  • 33
    • 33745964571 scopus 로고    scopus 로고
    • Anisotropic scaffolds facilitate enhanced neurite extension in vitro
    • Dodla M.C., and Bellamkonda R.V. Anisotropic scaffolds facilitate enhanced neurite extension in vitro. J. Biomed. Mater. Res. A 78A (2006) 213-221
    • (2006) J. Biomed. Mater. Res. A , vol.78 A , pp. 213-221
    • Dodla, M.C.1    Bellamkonda, R.V.2
  • 34
    • 0036339971 scopus 로고    scopus 로고
    • Three-dimensional morphometry of spinal cord injury following polyethylene glycol treatment
    • Duerstock B.S., and Borgens R.B. Three-dimensional morphometry of spinal cord injury following polyethylene glycol treatment. J. Exp. Biol. 205 (2002) 13-24
    • (2002) J. Exp. Biol. , vol.205 , pp. 13-24
    • Duerstock, B.S.1    Borgens, R.B.2
  • 35
    • 33646576505 scopus 로고    scopus 로고
    • Functional considerations of stem cell transplantation therapy for spinal cord repair
    • Enzmann G.U., Benton R.L., Talbott J.F., Cao Q., and Whittemore S.R. Functional considerations of stem cell transplantation therapy for spinal cord repair. J. Neurotrauma 23 (2006) 479-495
    • (2006) J. Neurotrauma , vol.23 , pp. 479-495
    • Enzmann, G.U.1    Benton, R.L.2    Talbott, J.F.3    Cao, Q.4    Whittemore, S.R.5
  • 36
    • 0037677771 scopus 로고    scopus 로고
    • Fiber templating of poly(2-hydroxyethyl methacrylate) for neural tissue engineering
    • Flynn L., Dalton P.D., and Shoichet M.S. Fiber templating of poly(2-hydroxyethyl methacrylate) for neural tissue engineering. Biomaterials 24 (2003) 4265-4272
    • (2003) Biomaterials , vol.24 , pp. 4265-4272
    • Flynn, L.1    Dalton, P.D.2    Shoichet, M.S.3
  • 37
    • 13944266687 scopus 로고    scopus 로고
    • Combining Schwann cell bridges and olfactory-ensheathing glia grafts with chondroitinase promotes locomotor recovery after complete transection of the spinal cord
    • Fouad K., Schnell L., Bunge M.B., Schwab M.E., Liebscher T., and Pearse D.D. Combining Schwann cell bridges and olfactory-ensheathing glia grafts with chondroitinase promotes locomotor recovery after complete transection of the spinal cord. J. Neurosci. 25 (2005) 1169-1178
    • (2005) J. Neurosci. , vol.25 , pp. 1169-1178
    • Fouad, K.1    Schnell, L.2    Bunge, M.B.3    Schwab, M.E.4    Liebscher, T.5    Pearse, D.D.6
  • 38
    • 36048962715 scopus 로고    scopus 로고
    • Olfactory ensheathing glia: their contribution to primary olfactory nervous system regeneration and their regenerative potential following transplantation into the injured spinal cord
    • Franssen E.H., de Bree F.M., and Verhaagen J. Olfactory ensheathing glia: their contribution to primary olfactory nervous system regeneration and their regenerative potential following transplantation into the injured spinal cord. Brain Res. Rev. 56 (2007) 236-258
    • (2007) Brain Res. Rev. , vol.56 , pp. 236-258
    • Franssen, E.H.1    de Bree, F.M.2    Verhaagen, J.3
  • 39
    • 20444364155 scopus 로고    scopus 로고
    • Controlling cell adhesion and degradation of chitosan films by N-acetylation
    • Freier T., Koh H.S., Kazazian K., and Shoichet M.S. Controlling cell adhesion and degradation of chitosan films by N-acetylation. Biomaterials 26 (2005) 5872-5878
    • (2005) Biomaterials , vol.26 , pp. 5872-5878
    • Freier, T.1    Koh, H.S.2    Kazazian, K.3    Shoichet, M.S.4
  • 40
    • 13944264357 scopus 로고    scopus 로고
    • Chitin-based tubes for tissue engineering in the nervous system
    • Freier T., Montenegro R., Shan Koh H., and Shoichet M.S. Chitin-based tubes for tissue engineering in the nervous system. Biomaterials 26 (2005) 4624-4632
    • (2005) Biomaterials , vol.26 , pp. 4624-4632
    • Freier, T.1    Montenegro, R.2    Shan Koh, H.3    Shoichet, M.S.4
  • 42
    • 0032534633 scopus 로고    scopus 로고
    • Poly (alpha-hydroxyacids) for application in the spinal cord: resorbability and biocompatibility with adult rat Schwann cells and spinal cord
    • Gautier S.E., Oudega M., Fragoso M., Chapon P., Plant G.W., Bunge M.B., and Parel J.M. Poly (alpha-hydroxyacids) for application in the spinal cord: resorbability and biocompatibility with adult rat Schwann cells and spinal cord. J. Biomed. Mater. Res. 42 (1998) 642-654
    • (1998) J. Biomed. Mater. Res. , vol.42 , pp. 642-654
    • Gautier, S.E.1    Oudega, M.2    Fragoso, M.3    Chapon, P.4    Plant, G.W.5    Bunge, M.B.6    Parel, J.M.7
  • 44
    • 26844485950 scopus 로고    scopus 로고
    • Neurite bridging across micropatterned grooves
    • Goldner J.S., Bruder J.M., Li G., and Gazzola D. Neurite bridging across micropatterned grooves. Biomaterials 27 (2006) 460-472
    • (2006) Biomaterials , vol.27 , pp. 460-472
    • Goldner, J.S.1    Bruder, J.M.2    Li, G.3    Gazzola, D.4
  • 45
    • 16944366150 scopus 로고    scopus 로고
    • Cellular delivery of neurotrophin-3 promotes corticospinal axonal growth and partial functional recovery after spinal cord injury
    • Grill R., Murai K., Blesch A., Gage F.H., and Tuszynski M.H. Cellular delivery of neurotrophin-3 promotes corticospinal axonal growth and partial functional recovery after spinal cord injury. J. Neurosci. 17 (1997) 5560-5572
    • (1997) J. Neurosci. , vol.17 , pp. 5560-5572
    • Grill, R.1    Murai, K.2    Blesch, A.3    Gage, F.H.4    Tuszynski, M.H.5
  • 46
    • 0031408944 scopus 로고    scopus 로고
    • Robust growth of chronically injured spinal cord axons induced by grafts of genetically modified NGF-secreting cells
    • Grill R.J., Blesch A., and Tuszynski M.H. Robust growth of chronically injured spinal cord axons induced by grafts of genetically modified NGF-secreting cells. Exp. Neurol. 148 (1997) 444-452
    • (1997) Exp. Neurol. , vol.148 , pp. 444-452
    • Grill, R.J.1    Blesch, A.2    Tuszynski, M.H.3
  • 47
    • 29244439335 scopus 로고    scopus 로고
    • Fast-gelling injectable blend of hyaluronan and methylcellulose for intrathecal, localized delivery to the injured spinal cord
    • Gupta D., Tator C.H., and Shoichet M.S. Fast-gelling injectable blend of hyaluronan and methylcellulose for intrathecal, localized delivery to the injured spinal cord. Biomaterials 27 (2006) 2370-2379
    • (2006) Biomaterials , vol.27 , pp. 2370-2379
    • Gupta, D.1    Tator, C.H.2    Shoichet, M.S.3
  • 48
    • 0034001128 scopus 로고    scopus 로고
    • A polymer foam conduit seeded with Schwann cells promotes guided peripheral nerve regeneration
    • Hadlock T., Sundback C., Hunter D., Cheney M., and Vacanti J.P. A polymer foam conduit seeded with Schwann cells promotes guided peripheral nerve regeneration. Tissue Eng. 6 (2000) 119-127
    • (2000) Tissue Eng. , vol.6 , pp. 119-127
    • Hadlock, T.1    Sundback, C.2    Hunter, D.3    Cheney, M.4    Vacanti, J.P.5
  • 49
    • 73349103199 scopus 로고    scopus 로고
    • Linear ordered collagen scaffolds loaded with collagen-binding brain-derived neurotrophic factor improve the recovery of spinal cord injury in rats
    • (Epub March 16, 2009)
    • Han Q., Sun W., Lin H., Zhao W., Gao Y., Zhao Y., Chen B., Xiao Z., Hu W., Li Y., Yang B., and Dai J. Linear ordered collagen scaffolds loaded with collagen-binding brain-derived neurotrophic factor improve the recovery of spinal cord injury in rats. Tissue Eng. A 16 (2009) (Epub March 16, 2009)
    • (2009) Tissue Eng. A , vol.16
    • Han, Q.1    Sun, W.2    Lin, H.3    Zhao, W.4    Gao, Y.5    Zhao, Y.6    Chen, B.7    Xiao, Z.8    Hu, W.9    Li, Y.10    Yang, B.11    Dai, J.12
  • 51
    • 33646561820 scopus 로고    scopus 로고
    • Bioengineered strategies for spinal cord repair
    • Hiroshi N., Tator C.H., and Shoichet M.S. Bioengineered strategies for spinal cord repair. J. Neurotrauma. 23 (2006) 496-507
    • (2006) J. Neurotrauma. , vol.23 , pp. 496-507
    • Hiroshi, N.1    Tator, C.H.2    Shoichet, M.S.3
  • 53
    • 0031664360 scopus 로고    scopus 로고
    • Collagen containing neurotrophin-3 (NT-3) attracts regrowing injured corticospinal axons in the adult rat spinal cord and promotes partial functional recovery
    • Houweling D.A., Lankhorst A.J., Gispen W.H., Bär P.R., and Joosten E.A.J. Collagen containing neurotrophin-3 (NT-3) attracts regrowing injured corticospinal axons in the adult rat spinal cord and promotes partial functional recovery. Exp. Neurol. 153 (1998) 49-59
    • (1998) Exp. Neurol. , vol.153 , pp. 49-59
    • Houweling, D.A.1    Lankhorst, A.J.2    Gispen, W.H.3    Bär, P.R.4    Joosten, E.A.J.5
  • 54
    • 26844448005 scopus 로고    scopus 로고
    • Poly (D,L-lactic acid) macroporous guidance scaffolds seeded with Schwann cells genetically modified to secrete a bi-functional neurotrophin implanted in the completely transected adult rat thoracic spinal cord
    • Hurtado A., Moon L.D., Maquet V., Blits B., Jerome R., and Oudega M. Poly (D,L-lactic acid) macroporous guidance scaffolds seeded with Schwann cells genetically modified to secrete a bi-functional neurotrophin implanted in the completely transected adult rat thoracic spinal cord. Biomaterials 27 (2006) 430-442
    • (2006) Biomaterials , vol.27 , pp. 430-442
    • Hurtado, A.1    Moon, L.D.2    Maquet, V.3    Blits, B.4    Jerome, R.5    Oudega, M.6
  • 55
    • 0141560588 scopus 로고    scopus 로고
    • Glial cell line-derived neurotrophic factor-enriched bridging transplants promote propriospinal axonal regeneration and enhance myelination after spinal cord injury
    • Iannotti C., Li H., Yan P., Lu X., Wirthlin L., and Xu X.M. Glial cell line-derived neurotrophic factor-enriched bridging transplants promote propriospinal axonal regeneration and enhance myelination after spinal cord injury. Exp. Neurol. 183 (2003) 379-393
    • (2003) Exp. Neurol. , vol.183 , pp. 379-393
    • Iannotti, C.1    Li, H.2    Yan, P.3    Lu, X.4    Wirthlin, L.5    Xu, X.M.6
  • 56
    • 26844574071 scopus 로고    scopus 로고
    • In situ gelling hydrogels for conformal repair of spinal cord defects, and local delivery of BDNF after spinal cord injury
    • Jain A., Kim Y.T., McKeon R.J., and Bellamkonda R.V. In situ gelling hydrogels for conformal repair of spinal cord defects, and local delivery of BDNF after spinal cord injury. Biomaterials 27 (2006) 497-504
    • (2006) Biomaterials , vol.27 , pp. 497-504
    • Jain, A.1    Kim, Y.T.2    McKeon, R.J.3    Bellamkonda, R.V.4
  • 57
    • 0023224826 scopus 로고
    • Permeable tubes increase the length of the gap that regenerating axons can span
    • Jeng C.B., and Coggeshall R.E. Permeable tubes increase the length of the gap that regenerating axons can span. Brain Res. 408 (1985) 239-242
    • (1985) Brain Res. , vol.408 , pp. 239-242
    • Jeng, C.B.1    Coggeshall, R.E.2
  • 58
    • 19344368945 scopus 로고    scopus 로고
    • Injectable intrathecal delivery system for localized administration of EGF and FGF-2 to the injured rat spinal cord
    • Jimenez Hamann M.C., Tator C.H., and Shoichet M.S. Injectable intrathecal delivery system for localized administration of EGF and FGF-2 to the injured rat spinal cord. Exp. Neurol. 194 (2005) 106-119
    • (2005) Exp. Neurol. , vol.194 , pp. 106-119
    • Jimenez Hamann, M.C.1    Tator, C.H.2    Shoichet, M.S.3
  • 59
    • 70350468652 scopus 로고    scopus 로고
    • Fibrin-based tissue engineering scaffolds enhance neural fiber sprouting and delay the accumulation of reactive astrocytes at the lesion in a subacute model of spinal cord injury
    • (Epub January 22, 2009)
    • Johnson P., Parker S., and Sakiyama-Elbert S. Fibrin-based tissue engineering scaffolds enhance neural fiber sprouting and delay the accumulation of reactive astrocytes at the lesion in a subacute model of spinal cord injury. J. Biomed. Mater. Res. A 22 (2009) (Epub January 22, 2009)
    • (2009) J. Biomed. Mater. Res. A , vol.22
    • Johnson, P.1    Parker, S.2    Sakiyama-Elbert, S.3
  • 60
    • 64549091117 scopus 로고    scopus 로고
    • A new paradigm for local and sustained release of therapeutic molecules to the injured spinal cord for neuroprotection and tissue repair
    • Kang C., Poon P., Tator C.H., and Shoichet M.S. A new paradigm for local and sustained release of therapeutic molecules to the injured spinal cord for neuroprotection and tissue repair. Tissue Eng. A 15 (2009) 595-604
    • (2009) Tissue Eng. A , vol.15 , pp. 595-604
    • Kang, C.1    Poon, P.2    Tator, C.H.3    Shoichet, M.S.4
  • 62
    • 0035809850 scopus 로고    scopus 로고
    • Alginate, a bioresorbable material derived from brown seaweed, enhances elongation of amputated axons of spinal cord in infant rats
    • Kataoka K., Suzuki Y., Kitada M., Ohnishi K., Suzuki K., Tanihara M., Ide C., Endo K., and Nishimura Y. Alginate, a bioresorbable material derived from brown seaweed, enhances elongation of amputated axons of spinal cord in infant rats. J. Biomed. Mater. Res. 54 (2001) 373-384
    • (2001) J. Biomed. Mater. Res. , vol.54 , pp. 373-384
    • Kataoka, K.1    Suzuki, Y.2    Kitada, M.3    Ohnishi, K.4    Suzuki, K.5    Tanihara, M.6    Ide, C.7    Endo, K.8    Nishimura, Y.9
  • 63
    • 72049132984 scopus 로고    scopus 로고
    • Hydrogel mediated delivery of trophic factors for neuronal repair
    • Katz J.S., and Burdick J.A. Hydrogel mediated delivery of trophic factors for neuronal repair. Rev. Nanomed. Nanobiotechnol. 1 (2009) 128-139
    • (2009) Rev. Nanomed. Nanobiotechnol. , vol.1 , pp. 128-139
    • Katz, J.S.1    Burdick, J.A.2
  • 64
    • 34748902324 scopus 로고    scopus 로고
    • Microengineered hydrogels for tissue engineering
    • Khademhosseini A., and Langer R. Microengineered hydrogels for tissue engineering. Biomaterials 28 (2007) 5087-5092
    • (2007) Biomaterials , vol.28 , pp. 5087-5092
    • Khademhosseini, A.1    Langer, R.2
  • 65
    • 32144463825 scopus 로고    scopus 로고
    • Sustained release of dexamethasone from hydrophilic matrices using PLGA nanoparticles for neural drug delivery
    • Kim D.H., and Martin D.C. Sustained release of dexamethasone from hydrophilic matrices using PLGA nanoparticles for neural drug delivery. Biomaterials 27 (2006) 3031-3037
    • (2006) Biomaterials , vol.27 , pp. 3031-3037
    • Kim, D.H.1    Martin, D.C.2
  • 66
    • 51849167277 scopus 로고    scopus 로고
    • Design of protein-releasing chitosan channels
    • Kim H., Tator C.H., and Shoichet M.S. Design of protein-releasing chitosan channels. Biotechnol. Prog. 24 (2008) 932-937
    • (2008) Biotechnol. Prog. , vol.24 , pp. 932-937
    • Kim, H.1    Tator, C.H.2    Shoichet, M.S.3
  • 67
    • 61349091026 scopus 로고    scopus 로고
    • Nanoparticle-mediated local delivery of methylprednisolone after spinal cord injury
    • Kim Y.T., Caldwell J.M., and Bellamkonda R.V. Nanoparticle-mediated local delivery of methylprednisolone after spinal cord injury. Biomaterials 30 (2009) 2582-2590
    • (2009) Biomaterials , vol.30 , pp. 2582-2590
    • Kim, Y.T.1    Caldwell, J.M.2    Bellamkonda, R.V.3
  • 68
    • 0042665647 scopus 로고    scopus 로고
    • Mats made from fibronectin support oriented growth of axons in the damaged spinal cord of the adult rat
    • King V.R., Henseler M., Brown R.A., and Priestley J.V. Mats made from fibronectin support oriented growth of axons in the damaged spinal cord of the adult rat. Exp. Neurol. 182 (2003) 383-398
    • (2003) Exp. Neurol. , vol.182 , pp. 383-398
    • King, V.R.1    Henseler, M.2    Brown, R.A.3    Priestley, J.V.4
  • 69
    • 42449096890 scopus 로고    scopus 로고
    • Polymeric biomaterials in tissue engineering
    • Kohane D., and Langer R. Polymeric biomaterials in tissue engineering. Pediatr. Res. 63 (2008) 487-491
    • (2008) Pediatr. Res. , vol.63 , pp. 487-491
    • Kohane, D.1    Langer, R.2
  • 71
    • 67651158286 scopus 로고    scopus 로고
    • Magnesium chloride in a polyethylene glycol formulation as a neuroprotective therapy for acute spinal cord injury: preclinical refinement and optimization
    • (Epub March 24, 2009)
    • Kwon B.K., Roy J., Lee J.H., Okon E.B., Zhang H., Marx J.C., and Kindy M.S. Magnesium chloride in a polyethylene glycol formulation as a neuroprotective therapy for acute spinal cord injury: preclinical refinement and optimization. J. Neurotrauma. 24 (2009) (Epub March 24, 2009)
    • (2009) J. Neurotrauma. , vol.24
    • Kwon, B.K.1    Roy, J.2    Lee, J.H.3    Okon, E.B.4    Zhang, H.5    Marx, J.C.6    Kindy, M.S.7
  • 72
    • 0035893632 scopus 로고    scopus 로고
    • Epidemiology, demographics, and pathophysiology of acute spinal cord injury
    • Lali H.S., Sekhon L.H.S., and Fehlings M.G. Epidemiology, demographics, and pathophysiology of acute spinal cord injury. Spine 26 (2001) S2-12
    • (2001) Spine , vol.26
    • Lali, H.S.1    Sekhon, L.H.S.2    Fehlings, M.G.3
  • 73
    • 52049099117 scopus 로고    scopus 로고
    • Respiratory neuroplasticity and cervical spinal cord injury
    • Lane M.A., Fuller D.D., White T.E., and Reier P.J. Respiratory neuroplasticity and cervical spinal cord injury. Trends Neurosci. 31 (2008) 538-547
    • (2008) Trends Neurosci. , vol.31 , pp. 538-547
    • Lane, M.A.1    Fuller, D.D.2    White, T.E.3    Reier, P.J.4
  • 75
    • 33748093069 scopus 로고    scopus 로고
    • Macroporous hydrogels based on 2-hydroxyethyl methacrylate. Part 4: growth of rat bone marrow stromal cells in three-dimensional hydrogels with positive and negative surface charges and in polyelectrolyte complexes
    • Lesny P., Pradny M., Jendelova P., Michalek J., Vacik J., and Sykova E. Macroporous hydrogels based on 2-hydroxyethyl methacrylate. Part 4: growth of rat bone marrow stromal cells in three-dimensional hydrogels with positive and negative surface charges and in polyelectrolyte complexes. J. Mater. Sci. Mater. Med. 17 (2006) 829-833
    • (2006) J. Mater. Sci. Mater. Med. , vol.17 , pp. 829-833
    • Lesny, P.1    Pradny, M.2    Jendelova, P.3    Michalek, J.4    Vacik, J.5    Sykova, E.6
  • 76
    • 34748870187 scopus 로고    scopus 로고
    • Application of scaffold materials in tissue reconstruction in immunocompetent mammals: our experience and future requirements
    • Liu W., and Cao Y. Application of scaffold materials in tissue reconstruction in immunocompetent mammals: our experience and future requirements. Biomaterials 28 (2007) 5078-5086
    • (2007) Biomaterials , vol.28 , pp. 5078-5086
    • Liu, W.1    Cao, Y.2
  • 77
    • 0034948287 scopus 로고    scopus 로고
    • The regrowth of axons within tissue defects in the CNS is promoted by implanted hydrogel matrices that contain BDNF and CNTF producing fibroblasts
    • Loh N.K., Woerly S., Bunt S.M., Wilton S.D., and Harvey A.R. The regrowth of axons within tissue defects in the CNS is promoted by implanted hydrogel matrices that contain BDNF and CNTF producing fibroblasts. Exp. Neurol. 170 (2001) 72-84
    • (2001) Exp. Neurol. , vol.170 , pp. 72-84
    • Loh, N.K.1    Woerly, S.2    Bunt, S.M.3    Wilton, S.D.4    Harvey, A.R.5
  • 78
    • 33847623792 scopus 로고    scopus 로고
    • Making human neurons from stem cells after spinal cord injury
    • Lowry N.A., and Temple S. Making human neurons from stem cells after spinal cord injury. PLoS Med. 4 (2007) e48
    • (2007) PLoS Med. , vol.4
    • Lowry, N.A.1    Temple, S.2
  • 79
    • 0037089383 scopus 로고    scopus 로고
    • Olfactory ensheathing cells: their potential use for repairing the injured spinal cord
    • Lu J., and Ashwell K. Olfactory ensheathing cells: their potential use for repairing the injured spinal cord. Spine 27 (2002) 887-892
    • (2002) Spine , vol.27 , pp. 887-892
    • Lu, J.1    Ashwell, K.2
  • 80
    • 0038054469 scopus 로고    scopus 로고
    • Neural stem cells constitutively secrete neurotrophic factors and promote extensive host axonal growth after spinal cord injury
    • Lu P., Jones L.L., Snyder E.Y., and Tuszynski M.H. Neural stem cells constitutively secrete neurotrophic factors and promote extensive host axonal growth after spinal cord injury. Exp. Neurol. 181 (2003) 115-129
    • (2003) Exp. Neurol. , vol.181 , pp. 115-129
    • Lu, P.1    Jones, L.L.2    Snyder, E.Y.3    Tuszynski, M.H.4
  • 81
    • 38649126573 scopus 로고    scopus 로고
    • Growth factors and combinatorial therapies for CNS regeneration
    • Lu P., and Tuszynski M.H. Growth factors and combinatorial therapies for CNS regeneration. Exp. Neurol. 209 (2008) 313-320
    • (2008) Exp. Neurol. , vol.209 , pp. 313-320
    • Lu, P.1    Tuszynski, M.H.2
  • 82
    • 7444236080 scopus 로고    scopus 로고
    • CNS stem and progenitor cell differentiation into functional neuronal circuits in three-dimensional collagen gels
    • Ma W., Fitzgerald W., Liu Q.Y., O'Shaughnessy T.J., Maric D., Lin H.J., Alkon D.L., and Barker J.L. CNS stem and progenitor cell differentiation into functional neuronal circuits in three-dimensional collagen gels. Exp. Neurol. 190 (2004) 276-288
    • (2004) Exp. Neurol. , vol.190 , pp. 276-288
    • Ma, W.1    Fitzgerald, W.2    Liu, Q.Y.3    O'Shaughnessy, T.J.4    Maric, D.5    Lin, H.J.6    Alkon, D.L.7    Barker, J.L.8
  • 83
    • 0025271268 scopus 로고
    • Clinical nerve reconstruction with a bioabsorbable polyglycolic acid tube
    • Mackinnon S.E., and Dellon A.L. Clinical nerve reconstruction with a bioabsorbable polyglycolic acid tube. Plast. Reconstr. Surg. 85 (1990) 419-424
    • (1990) Plast. Reconstr. Surg. , vol.85 , pp. 419-424
    • Mackinnon, S.E.1    Dellon, A.L.2
  • 85
    • 33746685619 scopus 로고    scopus 로고
    • Impact of cell type and density on nerve growth factor distribution and bioactivity in 3-dimensional collagen gel cultures
    • Mahoney M.J., Krewson C., Miller J., and Saltzman W.M. Impact of cell type and density on nerve growth factor distribution and bioactivity in 3-dimensional collagen gel cultures. Tissue Eng. 12 (2006) 1915-1927
    • (2006) Tissue Eng. , vol.12 , pp. 1915-1927
    • Mahoney, M.J.1    Krewson, C.2    Miller, J.3    Saltzman, W.M.4
  • 86
    • 0027537829 scopus 로고
    • Evaluation of two crosslinked collagen gels implanted in the transected spinal cord
    • Marchand R., Woerly S., Bertrnad L., and Valdes N. Evaluation of two crosslinked collagen gels implanted in the transected spinal cord. Brain Res. Bull. 30 (1993) 415-422
    • (1993) Brain Res. Bull. , vol.30 , pp. 415-422
    • Marchand, R.1    Woerly, S.2    Bertrnad, L.3    Valdes, N.4
  • 88
    • 0031814388 scopus 로고    scopus 로고
    • Schwann cells genetically modified to secrete human BDNF promote enhanced axonal regrowth across transected adult rat spinal cord
    • Menei P., Montero-Menei C., Whittemore S.R., Bunge R.P., and Bunge M.B. Schwann cells genetically modified to secrete human BDNF promote enhanced axonal regrowth across transected adult rat spinal cord. Eur. J. Neurosci. 10 (1998) 607-621
    • (1998) Eur. J. Neurosci. , vol.10 , pp. 607-621
    • Menei, P.1    Montero-Menei, C.2    Whittemore, S.R.3    Bunge, R.P.4    Bunge, M.B.5
  • 89
    • 33645509696 scopus 로고    scopus 로고
    • Immobilized concentration gradients of neurotrophic factors guide neurite outgrowth of primary neurons in macroporous scaffolds
    • Moore K., MacSween M., and Shoichet M. Immobilized concentration gradients of neurotrophic factors guide neurite outgrowth of primary neurons in macroporous scaffolds. Tissue Eng. 12 (2006) 267-278
    • (2006) Tissue Eng. , vol.12 , pp. 267-278
    • Moore, K.1    MacSween, M.2    Shoichet, M.3
  • 91
    • 47749143964 scopus 로고    scopus 로고
    • Epac mediates cyclic AMP-dependent axon growth, guidance and regeneration
    • Murray A.J., and Shewan D.A. Epac mediates cyclic AMP-dependent axon growth, guidance and regeneration. Mol. Cell. Neurosci. 38 (2008) 578-588
    • (2008) Mol. Cell. Neurosci. , vol.38 , pp. 578-588
    • Murray, A.J.1    Shewan, D.A.2
  • 92
    • 67349086271 scopus 로고    scopus 로고
    • Development of porous PEG hydrogels that enable efficient, uniform cell-seeding and permit early neural process extension
    • Namba R.M., Cole A.A., Bjugstad K.B., and Mahoney M.J. Development of porous PEG hydrogels that enable efficient, uniform cell-seeding and permit early neural process extension. Acta Biomater. 5 6 (2009) 1884-1897
    • (2009) Acta Biomater. , vol.5 , Issue.6 , pp. 1884-1897
    • Namba, R.M.1    Cole, A.A.2    Bjugstad, K.B.3    Mahoney, M.J.4
  • 93
    • 0037104763 scopus 로고    scopus 로고
    • Ensheathing cells and methylprednisolone promote axonal regeneration and functional recovery in the lesioned adult rat spinal cord
    • Nash H.H., Borke R.C., and Anders J.J. Ensheathing cells and methylprednisolone promote axonal regeneration and functional recovery in the lesioned adult rat spinal cord. J Neurosci. 22 (2002) 7111-7120
    • (2002) J Neurosci. , vol.22 , pp. 7111-7120
    • Nash, H.H.1    Borke, R.C.2    Anders, J.J.3
  • 96
    • 53549083781 scopus 로고    scopus 로고
    • Abnormalities of respiratory control and the respiratory motor unit
    • Nogues M.A., and Benarroch E. Abnormalities of respiratory control and the respiratory motor unit. Neurologist 14 5 (2008) 273-288
    • (2008) Neurologist , vol.14 , Issue.5 , pp. 273-288
    • Nogues, M.A.1    Benarroch, E.2
  • 97
    • 57049157215 scopus 로고    scopus 로고
    • Delayed implantation of intramedullary chitosan channels containing nerve grafts promotes extensive axonal regeneration after spinal cord injury
    • Nomura H., Baladie B., Katayama Y., Morshead C.M., Shoichet M.S., and Tator C.H. Delayed implantation of intramedullary chitosan channels containing nerve grafts promotes extensive axonal regeneration after spinal cord injury. Neurosurgery 63 (2008) 127-141
    • (2008) Neurosurgery , vol.63 , pp. 127-141
    • Nomura, H.1    Baladie, B.2    Katayama, Y.3    Morshead, C.M.4    Shoichet, M.S.5    Tator, C.H.6
  • 98
    • 33745774844 scopus 로고    scopus 로고
    • Complete spinal cord transection treated by implantation of a reinforced synthetic hydrogel channel results in syringomyelia and caudal migration of the rostral stump
    • Nomura H., Katayama Y., Shoichet M.S., and Tator C.H. Complete spinal cord transection treated by implantation of a reinforced synthetic hydrogel channel results in syringomyelia and caudal migration of the rostral stump. Neurosurgery 59 (2006) 183-192
    • (2006) Neurosurgery , vol.59 , pp. 183-192
    • Nomura, H.1    Katayama, Y.2    Shoichet, M.S.3    Tator, C.H.4
  • 99
    • 33646561820 scopus 로고    scopus 로고
    • Bioengineered strategies for spinal cord repair
    • Nomura H., Tator C., and Shoichet M. Bioengineered strategies for spinal cord repair. J. Neurotrauma. 23 (2006) 496-507
    • (2006) J. Neurotrauma. , vol.23 , pp. 496-507
    • Nomura, H.1    Tator, C.2    Shoichet, M.3
  • 100
    • 43649100748 scopus 로고    scopus 로고
    • Extramedullary chitosan channels promote survival of transplanted neural stem and progenitor cells and create a tissue bridge after complete spinal cord transection
    • Nomura H., Zahir T., Kim H., Katayama Y., Kulbatski I., Morshead C.M., Shoichet M.S., and Tator C.H. Extramedullary chitosan channels promote survival of transplanted neural stem and progenitor cells and create a tissue bridge after complete spinal cord transection. Tissue Eng. A 14 (2008) 649-665
    • (2008) Tissue Eng. A , vol.14 , pp. 649-665
    • Nomura, H.1    Zahir, T.2    Kim, H.3    Katayama, Y.4    Kulbatski, I.5    Morshead, C.M.6    Shoichet, M.S.7    Tator, C.H.8
  • 102
    • 72049110861 scopus 로고    scopus 로고
    • Soluble factors from neocortical astrocytes enhance neuronal differentiation of neural progenitor cells from adult rat hippocampus on micropatterned polymer substrates
    • (Epub November 4, 2008)
    • Oh J., Recknor J.B., Recknor J.C., Mallapragada S.K., and Sakaguchi D.S. Soluble factors from neocortical astrocytes enhance neuronal differentiation of neural progenitor cells from adult rat hippocampus on micropatterned polymer substrates. J. Biomed. Mater. Res. A 4 (2008) (Epub November 4, 2008)
    • (2008) J. Biomed. Mater. Res. A , vol.4
    • Oh, J.1    Recknor, J.B.2    Recknor, J.C.3    Mallapragada, S.K.4    Sakaguchi, D.S.5
  • 103
    • 67650682083 scopus 로고    scopus 로고
    • Neural stem cell- and schwann cell-loaded biodegradable polymer scaffolds support axonal regeneration in the transected spinal cord
    • Olson H.E., Rooney G.E., Gross L., Nesbitt J.J., Galvin K.E., Knight A., Chen B., Yaszemski M.J., and Windebank A.J. Neural stem cell- and schwann cell-loaded biodegradable polymer scaffolds support axonal regeneration in the transected spinal cord. Tissue Eng. A 15 7 (2009) 1797-1805
    • (2009) Tissue Eng. A , vol.15 , Issue.7 , pp. 1797-1805
    • Olson, H.E.1    Rooney, G.E.2    Gross, L.3    Nesbitt, J.J.4    Galvin, K.E.5    Knight, A.6    Chen, B.7    Yaszemski, M.J.8    Windebank, A.J.9
  • 104
    • 0035105711 scopus 로고    scopus 로고
    • Axonal regeneration into Schwann cell grafts within resorbable poly(α-hydroxyacid) guidance channels in the adult rat spinal cord
    • Oudega M., Gautier S.E., Chapon P., Fragoso M., Bates M.L., Parel J.M., and Bunge M.B. Axonal regeneration into Schwann cell grafts within resorbable poly(α-hydroxyacid) guidance channels in the adult rat spinal cord. Biomaterials 22 (2001) 1125-1136
    • (2001) Biomaterials , vol.22 , pp. 1125-1136
    • Oudega, M.1    Gautier, S.E.2    Chapon, P.3    Fragoso, M.4    Bates, M.L.5    Parel, J.M.6    Bunge, M.B.7
  • 105
    • 0030222129 scopus 로고    scopus 로고
    • Nerve growth factor promotes regeneration of sensory axons into adult rat spinal cord
    • Oudega M., and Hagg T. Nerve growth factor promotes regeneration of sensory axons into adult rat spinal cord. Exp. Neurol. 140 (1996) 218-229
    • (1996) Exp. Neurol. , vol.140 , pp. 218-229
    • Oudega, M.1    Hagg, T.2
  • 106
    • 0033550707 scopus 로고    scopus 로고
    • Neurotrophins promote regeneration of sensory axons in the adult rat spinal cord
    • Oudega M., and Hagg T. Neurotrophins promote regeneration of sensory axons in the adult rat spinal cord. Brain Res. 818 (1999) 431-438
    • (1999) Brain Res. , vol.818 , pp. 431-438
    • Oudega, M.1    Hagg, T.2
  • 108
    • 0347754986 scopus 로고    scopus 로고
    • Freeze-dried poly(D,L-lactic acid) macroporous guidance scaffolds impregnated with brain-derived neurotrophic factor in the transected adult rat thoracic spinal cord
    • Patist C.M., Mulder M.B., Gautier S.E., Maquet V., Jerome R., and Oudega M. Freeze-dried poly(D,L-lactic acid) macroporous guidance scaffolds impregnated with brain-derived neurotrophic factor in the transected adult rat thoracic spinal cord. Biomaterials 25 (2004) 1569-1582
    • (2004) Biomaterials , vol.25 , pp. 1569-1582
    • Patist, C.M.1    Mulder, M.B.2    Gautier, S.E.3    Maquet, V.4    Jerome, R.5    Oudega, M.6
  • 111
    • 1042298995 scopus 로고    scopus 로고
    • Fluid shear in viscous fibronectin gels allows aggregation of fibrous materials for CNS tissue engineering
    • Phillips J.B., King V.R., Ward Z., Porter R.A., Priestley J.V., and Brown R.A. Fluid shear in viscous fibronectin gels allows aggregation of fibrous materials for CNS tissue engineering. Biomaterials 25 (2004) 2769-2779
    • (2004) Biomaterials , vol.25 , pp. 2769-2779
    • Phillips, J.B.1    King, V.R.2    Ward, Z.3    Porter, R.A.4    Priestley, J.V.5    Brown, R.A.6
  • 112
    • 33748430801 scopus 로고    scopus 로고
    • An injectable, biodegradable hydrogel for trophic factor delivery enhances axonal rewiring and improves performance after spinal cord injury
    • Piantino J., Burdick J.A., Goldberg D., Langer R., and Benowitz L.I. An injectable, biodegradable hydrogel for trophic factor delivery enhances axonal rewiring and improves performance after spinal cord injury. Exp. Neurol. 201 (2006) 359-367
    • (2006) Exp. Neurol. , vol.201 , pp. 359-367
    • Piantino, J.1    Burdick, J.A.2    Goldberg, D.3    Langer, R.4    Benowitz, L.I.5
  • 113
    • 0035370177 scopus 로고    scopus 로고
    • Conduction of impulses by axons regenerated in a Schwann cell graft in the transected adult rat thoracic spinal cord
    • Pinzon A., Calancie B., Oudega M., and Noga B.R. Conduction of impulses by axons regenerated in a Schwann cell graft in the transected adult rat thoracic spinal cord. J. Neurosci. Res. 64 (2001) 533-541
    • (2001) J. Neurosci. Res. , vol.64 , pp. 533-541
    • Pinzon, A.1    Calancie, B.2    Oudega, M.3    Noga, B.R.4
  • 114
    • 28744436393 scopus 로고    scopus 로고
    • Nerve guidance channels as drug delivery vehicles
    • Piotrowicz A., and Shoichet M. Nerve guidance channels as drug delivery vehicles. Biomaterials 27 (2006) 2018-2027
    • (2006) Biomaterials , vol.27 , pp. 2018-2027
    • Piotrowicz, A.1    Shoichet, M.2
  • 115
    • 0031847665 scopus 로고    scopus 로고
    • Implantation of collagen IV/poly(2-hyroxyethyl methacrylate) hydrogels containing Schwann cells into the lesioned rat optic tract
    • Plant G.W., Chirila T.V., and Harvey A.R. Implantation of collagen IV/poly(2-hyroxyethyl methacrylate) hydrogels containing Schwann cells into the lesioned rat optic tract. Cell Transplant. 7 (1998) 381-391
    • (1998) Cell Transplant. , vol.7 , pp. 381-391
    • Plant, G.W.1    Chirila, T.V.2    Harvey, A.R.3
  • 116
    • 0028950145 scopus 로고
    • Axonal growth within poly(2-hydroxyethyl methacrylate) sponges infiltrated with Schwann cells and implanted into the lesioned rat optic tract
    • Plant G.W., Harvey A.R., and Chirila T.V. Axonal growth within poly(2-hydroxyethyl methacrylate) sponges infiltrated with Schwann cells and implanted into the lesioned rat optic tract. Brain Res. 671 (1995) 119-130
    • (1995) Brain Res. , vol.671 , pp. 119-130
    • Plant, G.W.1    Harvey, A.R.2    Chirila, T.V.3
  • 117
    • 0029782557 scopus 로고    scopus 로고
    • The injured spinal cord: imaging, histopathologic, clinical correlates, and basic science approaches to enhancing neural function after spinal cord injury
    • Quencer R., and Bunge R.P. The injured spinal cord: imaging, histopathologic, clinical correlates, and basic science approaches to enhancing neural function after spinal cord injury. Spine 21 (1996) 2064-2066
    • (1996) Spine , vol.21 , pp. 2064-2066
    • Quencer, R.1    Bunge, R.P.2
  • 118
    • 0033757632 scopus 로고    scopus 로고
    • Functional recovery of paraplegic rats and motor axon regeneration in their spinal cords by olfactory ensheathing glia
    • Ramon-Cueto A., Cordero M.I., Santos-Benito F.F., and Avila J. Functional recovery of paraplegic rats and motor axon regeneration in their spinal cords by olfactory ensheathing glia. Neuron 25 (2000) 425-435
    • (2000) Neuron , vol.25 , pp. 425-435
    • Ramon-Cueto, A.1    Cordero, M.I.2    Santos-Benito, F.F.3    Avila, J.4
  • 119
    • 0000635530 scopus 로고    scopus 로고
    • Long-distance axonal regeneration in the transected adult rat spinal cord is promoted by olfactory ensheathing glia transplants
    • Ramon-Cueto A., Plant G.W., Avila J., and Bunge M.B. Long-distance axonal regeneration in the transected adult rat spinal cord is promoted by olfactory ensheathing glia transplants. J. Neurosci. 18 (1998) 3803-3815
    • (1998) J. Neurosci. , vol.18 , pp. 3803-3815
    • Ramon-Cueto, A.1    Plant, G.W.2    Avila, J.3    Bunge, M.B.4
  • 120
    • 33646069376 scopus 로고    scopus 로고
    • Directed growth and selective differentiation of neural progenitor cells on micropatterned polymer substrates
    • Recknor J.B., Sakaguchi D.S., and Mallapragada S.K. Directed growth and selective differentiation of neural progenitor cells on micropatterned polymer substrates. Biomaterials 27 (2006) 4098-4108
    • (2006) Biomaterials , vol.27 , pp. 4098-4108
    • Recknor, J.B.1    Sakaguchi, D.S.2    Mallapragada, S.K.3
  • 121
    • 37849014854 scopus 로고    scopus 로고
    • Transplantation of porous tubes following spinal cord transection improves hindlimb function in the rat
    • Reynolds L.F., Bren M.C., Wilson B.C., Gibson G.D., Shoichet M.S., and Murphy R.J. Transplantation of porous tubes following spinal cord transection improves hindlimb function in the rat. Spinal Cord 46 (2008) 58-64
    • (2008) Spinal Cord , vol.46 , pp. 58-64
    • Reynolds, L.F.1    Bren, M.C.2    Wilson, B.C.3    Gibson, G.D.4    Shoichet, M.S.5    Murphy, R.J.6
  • 122
    • 0018908523 scopus 로고
    • Axons from CNS neurons regenerate into PNS grafts
    • Richardson P.M., McGuinness U.M., and Aguayo A.J. Axons from CNS neurons regenerate into PNS grafts. Nature 284 (1980) 264-265
    • (1980) Nature , vol.284 , pp. 264-265
    • Richardson, P.M.1    McGuinness, U.M.2    Aguayo, A.J.3
  • 123
    • 0035987089 scopus 로고    scopus 로고
    • Transplantation of embryonal spinal cord nerve cells cultured on biodegradable microcarriers followed by low power laser irradiation for the treatment of traumatic paraplegia in rats
    • Rochkind S., Shahar A., Amon M., and Nevo Z. Transplantation of embryonal spinal cord nerve cells cultured on biodegradable microcarriers followed by low power laser irradiation for the treatment of traumatic paraplegia in rats. Neurol. Res. 24 (2002) 355-360
    • (2002) Neurol. Res. , vol.24 , pp. 355-360
    • Rochkind, S.1    Shahar, A.2    Amon, M.3    Nevo, Z.4
  • 125
    • 3242700527 scopus 로고    scopus 로고
    • Making tissue engineering scaffolds work. Review: the application of solid freeform fabrication technology to the production of tissue engineering scaffolds
    • Sachlos E., and Czernuszka J.T. Making tissue engineering scaffolds work. Review: the application of solid freeform fabrication technology to the production of tissue engineering scaffolds. Eur. Cell. Mater. 5 (2003) 29-39
    • (2003) Eur. Cell. Mater. , vol.5 , pp. 29-39
    • Sachlos, E.1    Czernuszka, J.T.2
  • 126
    • 34147094231 scopus 로고    scopus 로고
    • Guidance of glial cell migration and axonal growth on electrospun nanofibers of poly-epsilon-caprolactone and a collagen/poly-epsilon-caprolactone blend
    • Schnell E., Klinkhammer K., Balzer S., Brook G., Klee D., Dalton P., and Mey J. Guidance of glial cell migration and axonal growth on electrospun nanofibers of poly-epsilon-caprolactone and a collagen/poly-epsilon-caprolactone blend. Biomaterials 28 (2007) 3012-3025
    • (2007) Biomaterials , vol.28 , pp. 3012-3025
    • Schnell, E.1    Klinkhammer, K.2    Balzer, S.3    Brook, G.4    Klee, D.5    Dalton, P.6    Mey, J.7
  • 127
    • 34347335569 scopus 로고    scopus 로고
    • Intrathecal drug delivery is safe and efficacious for localized delivery to the spinal cord
    • Shoichet M.S., Tator C.H., Poon P., Kang C., and Baumann M.D. Intrathecal drug delivery is safe and efficacious for localized delivery to the spinal cord. Prog. Brain Res. 161 (2007) 385-392
    • (2007) Prog. Brain Res. , vol.161 , pp. 385-392
    • Shoichet, M.S.1    Tator, C.H.2    Poon, P.3    Kang, C.4    Baumann, M.D.5
  • 130
    • 0033230863 scopus 로고    scopus 로고
    • Effects of schwann cell suspension grafts on axon regeneration in subacute and chronic CNS traumatic injuries
    • Stichel C.C., Hermanns S., Lausberg F., and Muller H.W. Effects of schwann cell suspension grafts on axon regeneration in subacute and chronic CNS traumatic injuries. Glia 28 (1999) 156-165
    • (1999) Glia , vol.28 , pp. 156-165
    • Stichel, C.C.1    Hermanns, S.2    Lausberg, F.3    Muller, H.W.4
  • 132
    • 2542506229 scopus 로고    scopus 로고
    • The fabrication and characterization of linearly oriented nerve guidance scaffolds for spinal cord injury
    • Stokols S., and Tuszynski M.H. The fabrication and characterization of linearly oriented nerve guidance scaffolds for spinal cord injury. Biomaterials 25 (2004) 5839-5846
    • (2004) Biomaterials , vol.25 , pp. 5839-5846
    • Stokols, S.1    Tuszynski, M.H.2
  • 133
    • 26844557081 scopus 로고    scopus 로고
    • Freeze-dried agarose scaffolds with uniaxial channels stimulate and guide linear axonal growth following spinal cord injury
    • Stokols S., and Tuszynski M.H. Freeze-dried agarose scaffolds with uniaxial channels stimulate and guide linear axonal growth following spinal cord injury. Biomaterials 27 (2006) 443-451
    • (2006) Biomaterials , vol.27 , pp. 443-451
    • Stokols, S.1    Tuszynski, M.H.2
  • 135
    • 0036674855 scopus 로고    scopus 로고
    • Partial return of motor function in paralyzed legs after surgical bypass of the lesion site by nerve autografts three years after spinal cord injury
    • Tadie M., Liu S., Robert R., Guiheneuc P., Pereon Y., Perrouin-Verbe B., and Mathe J.F. Partial return of motor function in paralyzed legs after surgical bypass of the lesion site by nerve autografts three years after spinal cord injury. J Neurotrauma. 19 (2002) 909-916
    • (2002) J Neurotrauma. , vol.19 , pp. 909-916
    • Tadie, M.1    Liu, S.2    Robert, R.3    Guiheneuc, P.4    Pereon, Y.5    Perrouin-Verbe, B.6    Mathe, J.F.7
  • 137
    • 33745504598 scopus 로고    scopus 로고
    • Delivery of neurotrophin-3 from fibrin enhances neuronal fiber sprouting after spinal cord injury
    • Taylor S.J., Rosenzweig E.S., McDonald J.W., and Sakiyama-Elbert S.E. Delivery of neurotrophin-3 from fibrin enhances neuronal fiber sprouting after spinal cord injury. J. Control. Release 113 (2006) 226-235
    • (2006) J. Control. Release , vol.113 , pp. 226-235
    • Taylor, S.J.1    Rosenzweig, E.S.2    McDonald, J.W.3    Sakiyama-Elbert, S.E.4
  • 138
    • 33845193518 scopus 로고    scopus 로고
    • Effect of controlled delivery of neurotrophin-3 from fibrin on spinal cord injury in a long term model
    • Taylor S.J., and Sakiyama-Elbert S.E. Effect of controlled delivery of neurotrophin-3 from fibrin on spinal cord injury in a long term model. J. Control. Release 116 (2006) 204-210
    • (2006) J. Control. Release , vol.116 , pp. 204-210
    • Taylor, S.J.1    Sakiyama-Elbert, S.E.2
  • 139
  • 140
    • 3042736707 scopus 로고    scopus 로고
    • Synthetic hydrogel guidance channels facilitate regeneration of adult rat brainstem motor axons after complete spinal cord transection
    • Tsai E.C., Dalton P.D., Shoichet M.S., and Tator C.H. Synthetic hydrogel guidance channels facilitate regeneration of adult rat brainstem motor axons after complete spinal cord transection. J. Neurotrauma. 21 (2004) 789-804
    • (2004) J. Neurotrauma. , vol.21 , pp. 789-804
    • Tsai, E.C.1    Dalton, P.D.2    Shoichet, M.S.3    Tator, C.H.4
  • 141
    • 26844526040 scopus 로고    scopus 로고
    • Matrix inclusion within synthetic hydrogel guidance channels improves specific supraspinal and local axonal regeneration after complete spinal cord transection
    • Tsai E.C., Dalton P.D., Shoichet M.S., and Tator C.H. Matrix inclusion within synthetic hydrogel guidance channels improves specific supraspinal and local axonal regeneration after complete spinal cord transection. Biomaterials 27 (2006) 519-533
    • (2006) Biomaterials , vol.27 , pp. 519-533
    • Tsai, E.C.1    Dalton, P.D.2    Shoichet, M.S.3    Tator, C.H.4
  • 144
    • 65349149957 scopus 로고    scopus 로고
    • Photo-crosslinked poly(epsilon-caprolactone fumarate) networks for guided peripheral nerve regeneration: material properties and preliminary biological evaluations
    • Wang S., Yaszemski M.J., Knight A.M., Gruetzmacher J.A., Windebank A.J., and Lu L. Photo-crosslinked poly(epsilon-caprolactone fumarate) networks for guided peripheral nerve regeneration: material properties and preliminary biological evaluations. Acta Biomater. 5 5 (2009) 1531-1542
    • (2009) Acta Biomater. , vol.5 , Issue.5 , pp. 1531-1542
    • Wang, S.1    Yaszemski, M.J.2    Knight, A.M.3    Gruetzmacher, J.A.4    Windebank, A.J.5    Lu, L.6
  • 145
    • 52049108266 scopus 로고    scopus 로고
    • Sustained intraspinal delivery of neurotrophic factor encapsulated in biodegradable nanoparticles following contusive spinal cord injury
    • Wang Y.C., Wu Y.T., Huang H.Y., Lin H.I., Lo L.W., Tzeng S.F., and Yang C.S. Sustained intraspinal delivery of neurotrophic factor encapsulated in biodegradable nanoparticles following contusive spinal cord injury. Biomaterials 29 (2008) 4546-4553
    • (2008) Biomaterials , vol.29 , pp. 4546-4553
    • Wang, Y.C.1    Wu, Y.T.2    Huang, H.Y.3    Lin, H.I.4    Lo, L.W.5    Tzeng, S.F.6    Yang, C.S.7
  • 146
    • 33748775190 scopus 로고    scopus 로고
    • Optimization of fibrin scaffolds for differentiation of murine embryonic stem cells into neural lineage cells
    • Willerth S.M., Arendas K.J., Gottlieb D.I., and Sakiyama-Elbert S.E. Optimization of fibrin scaffolds for differentiation of murine embryonic stem cells into neural lineage cells. Biomaterials 27 (2006) 5990-6003
    • (2006) Biomaterials , vol.27 , pp. 5990-6003
    • Willerth, S.M.1    Arendas, K.J.2    Gottlieb, D.I.3    Sakiyama-Elbert, S.E.4
  • 147
    • 34748906596 scopus 로고    scopus 로고
    • The effects of soluble growth factors on embryonic stem cell differentiation inside of fibrin scaffolds
    • Willerth S.M., Faxel T.E., Gottlieb D.I., and Sakiyama-Elbert S.E. The effects of soluble growth factors on embryonic stem cell differentiation inside of fibrin scaffolds. Stem Cells 25 (2007) 2235-2244
    • (2007) Stem Cells , vol.25 , pp. 2235-2244
    • Willerth, S.M.1    Faxel, T.E.2    Gottlieb, D.I.3    Sakiyama-Elbert, S.E.4
  • 148
    • 34249951852 scopus 로고    scopus 로고
    • Approaches to neural tissue engineering using scaffolds for drug delivery
    • Willerth S.M., and Sakiyama-Elbert S.E. Approaches to neural tissue engineering using scaffolds for drug delivery. Adv. Drug. Deliv. Rev. 59 (2007) 325-338
    • (2007) Adv. Drug. Deliv. Rev. , vol.59 , pp. 325-338
    • Willerth, S.M.1    Sakiyama-Elbert, S.E.2
  • 151
    • 0035098617 scopus 로고    scopus 로고
    • Spinal cord repair with PHPMA hydrogel containing RGD peptides (NeuroGel)
    • Woerly S., Pinet E., de Robertis L., Van Diep D., and Bousmina M. Spinal cord repair with PHPMA hydrogel containing RGD peptides (NeuroGel). Biomaterials 22 (2001) 1095-1111
    • (2001) Biomaterials , vol.22 , pp. 1095-1111
    • Woerly, S.1    Pinet, E.2    de Robertis, L.3    Van Diep, D.4    Bousmina, M.5
  • 153
    • 55249093369 scopus 로고    scopus 로고
    • The differentiation of embryonic stem cells seeded on electrospun nanofibers into neural lineages
    • Xie J., Willerth S.M., Li X., Macewan M.R., Rader A., Sakiyama-Elbert S.E., and Xia Y. The differentiation of embryonic stem cells seeded on electrospun nanofibers into neural lineages. Biomaterials 30 (2009) 354-362
    • (2009) Biomaterials , vol.30 , pp. 354-362
    • Xie, J.1    Willerth, S.M.2    Li, X.3    Macewan, M.R.4    Rader, A.5    Sakiyama-Elbert, S.E.6    Xia, Y.7
  • 154
    • 0028870347 scopus 로고
    • Axonal regeneration into Schwann cell-seeded guidance channels grafted into transected adult rat spinal cord
    • Xu X.M., Guenard V., Kleitman N., and Bunge M.B. Axonal regeneration into Schwann cell-seeded guidance channels grafted into transected adult rat spinal cord. J. Comp. Neurol. 351 (1995) 145-160
    • (1995) J. Comp. Neurol. , vol.351 , pp. 145-160
    • Xu, X.M.1    Guenard, V.2    Kleitman, N.3    Bunge, M.B.4
  • 155
    • 10044289544 scopus 로고    scopus 로고
    • Electrospinning of nano/micro scale poly(L-lactic acid) aligned fibers and their potential in neural tissue engineering
    • Yang F., Murugan R., Wang S., and Ramakrishna S. Electrospinning of nano/micro scale poly(L-lactic acid) aligned fibers and their potential in neural tissue engineering. Biomaterials 26 (2005) 2603-2610
    • (2005) Biomaterials , vol.26 , pp. 2603-2610
    • Yang, F.1    Murugan, R.2    Wang, S.3    Ramakrishna, S.4
  • 157
    • 72049123291 scopus 로고    scopus 로고
    • The effect of laminin peptide gradient of enzymatically cross-linked collagen scaffold on neurite growth
    • (Epub February 11, 2009)
    • Yao L., Damodaran G., Nikolskaya N., Gorman A.M., Windebank A.J., and Pandit A. The effect of laminin peptide gradient of enzymatically cross-linked collagen scaffold on neurite growth. J. Biomed. Mater. Res. A 11 (2009) (Epub February 11, 2009)
    • (2009) J. Biomed. Mater. Res. A , vol.11
    • Yao, L.1    Damodaran, G.2    Nikolskaya, N.3    Gorman, A.M.4    Windebank, A.J.5    Pandit, A.6
  • 160
    • 64349084930 scopus 로고    scopus 로고
    • Functional restoration of rabbit spinal cord using collagen-filament scaffold
    • Yoshii S., Ito S., Shima M., Taniguchi A., and Akagi M. Functional restoration of rabbit spinal cord using collagen-filament scaffold. J. Tissue Eng. Regen. Med. 3 (2009) 19-25
    • (2009) J. Tissue Eng. Regen. Med. , vol.3 , pp. 19-25
    • Yoshii, S.1    Ito, S.2    Shima, M.3    Taniguchi, A.4    Akagi, M.5
  • 161
    • 4344674172 scopus 로고    scopus 로고
    • Restoration of function after spinal cord transection using a collagen bridge
    • Yoshii S., Shima M., Taniguchi A., and Akagi M. Restoration of function after spinal cord transection using a collagen bridge. J. Biomed. Mater. Res. A 70 (2004) 569-575
    • (2004) J. Biomed. Mater. Res. A , vol.70 , pp. 569-575
    • Yoshii, S.1    Shima, M.2    Taniguchi, A.3    Akagi, M.4
  • 162
    • 34250157368 scopus 로고    scopus 로고
    • Peptide surface modification of methacrylamide chitosan for neural tissue engineering applications
    • Yu L.M., Kazazian K., and Shoichet M.S. Peptide surface modification of methacrylamide chitosan for neural tissue engineering applications. J. Biomed. Mater. Res. A 82 (2007) 243-255
    • (2007) J. Biomed. Mater. Res. A , vol.82 , pp. 243-255
    • Yu, L.M.1    Kazazian, K.2    Shoichet, M.S.3
  • 163
    • 7444267844 scopus 로고    scopus 로고
    • Guided cell adhesion and outgrowth in peptide-modified channels for neural tissue engineering
    • Yu T.T., and Shoichet M.S. Guided cell adhesion and outgrowth in peptide-modified channels for neural tissue engineering. Biomaterials 26 (2005) 1507-1514
    • (2005) Biomaterials , vol.26 , pp. 1507-1514
    • Yu, T.T.1    Shoichet, M.S.2
  • 164
    • 1642377825 scopus 로고    scopus 로고
    • The interaction of Schwann cells with Chitosan membranes and fibres in vitro
    • Yuan Y., Zhang P., Yang Y., Wang X., and Gu X. The interaction of Schwann cells with Chitosan membranes and fibres in vitro. Biomaterials 25 (2004) 4273-4278
    • (2004) Biomaterials , vol.25 , pp. 4273-4278
    • Yuan, Y.1    Zhang, P.2    Yang, Y.3    Wang, X.4    Gu, X.5
  • 165
  • 166
    • 47649114017 scopus 로고    scopus 로고
    • Biomaterials for the central nervous system
    • Zhong Y., and Bellamkonda R.V. Biomaterials for the central nervous system. J. R. Soc. Interface 5 (2008) 957-975
    • (2008) J. R. Soc. Interface , vol.5 , pp. 957-975
    • Zhong, Y.1    Bellamkonda, R.V.2
  • 167
    • 38649132905 scopus 로고    scopus 로고
    • Effect of spinal cord injury on the neural regulation of respiratory function
    • Zimmer M.B., Nantwi K., and Goshgarian H.G. Effect of spinal cord injury on the neural regulation of respiratory function. Exp. Neurol. 209 (2007) 399-406
    • (2007) Exp. Neurol. , vol.209 , pp. 399-406
    • Zimmer, M.B.1    Nantwi, K.2    Goshgarian, H.G.3


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