메뉴 건너뛰기




Volumn 765, Issue 2, 1997, Pages 283-290

Impaired mitochondrial function, oxidative stress and altered antioxidant enzyme activities following traumatic spinal cord injury

Author keywords

Catalase; Excitotoxicity; Glutathione peroxidase; Lipid peroxidation; Mitochondrial metabolic activity; Neuron degeneration; Reactive oxygen species; Superoxide dismutase

Indexed keywords

CATALASE; GLUTAMIC ACID; GLUTATHIONE; LIPID; MALONALDEHYDE; NUCLEIC ACID; PROTEIN; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

EID: 0030981722     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(97)00573-8     Document Type: Article
Times cited : (276)

References (72)
  • 1
    • 0027288332 scopus 로고
    • Pathophysiology of spinal cord trauma
    • D. Anderson, E. Hall, Pathophysiology of spinal cord trauma, Ann. Emerg. Med. 22 (1993) 987-992.
    • (1993) Ann. Emerg. Med. , vol.22 , pp. 987-992
    • Anderson, D.1    Hall, E.2
  • 2
    • 0027162860 scopus 로고
    • Lipid peroxidation in experimental spinal cord injury: Time-level relationship
    • S. Barut, A. Canbolat, T. Bilge, Y. Aydin, B. Cokneseli, U. Kaya, Lipid peroxidation in experimental spinal cord injury: time-level relationship, Neurosurg. Rev. 16 (1993) 53-59.
    • (1993) Neurosurg. Rev. , vol.16 , pp. 53-59
    • Barut, S.1    Canbolat, A.2    Bilge, T.3    Aydin, Y.4    Cokneseli, B.5    Kaya, U.6
  • 3
    • 0030157694 scopus 로고    scopus 로고
    • Graded histological and locomotor outcomes after spinal cord contusion using the NYU weight-drop device versus transection
    • D. Basso, M. Beattie, J. Breshnahan, Graded histological and locomotor outcomes after spinal cord contusion using the NYU weight-drop device versus transection, Exp. Neurol. 139 (1996) 244-256.
    • (1996) Exp. Neurol. , vol.139 , pp. 244-256
    • Basso, D.1    Beattie, M.2    Breshnahan, J.3
  • 4
    • 0029125857 scopus 로고
    • Aging, energy, and oxidative stress in neurodegenerative diseases
    • M. Beal, Aging, energy, and oxidative stress in neurodegenerative diseases, Ann. Neurol. 38 (1995) 357-366.
    • (1995) Ann. Neurol. , vol.38 , pp. 357-366
    • Beal, M.1
  • 5
    • 0027280338 scopus 로고
    • Pathological implications of nitric oxide, superoxide and peroxynitrite formation
    • J. Beckman, J. Crow, Pathological implications of nitric oxide, superoxide and peroxynitrite formation, Biochem. Soc. Trans. 21 (1993) 330-334.
    • (1993) Biochem. Soc. Trans. , vol.21 , pp. 330-334
    • Beckman, J.1    Crow, J.2
  • 6
    • 0027302430 scopus 로고
    • The relationship between excitotoxicity and oxidative stress in the central nervous system
    • S.C. Bondy, C.P. LeBel, The relationship between excitotoxicity and oxidative stress in the central nervous system, Free Radic. Biol. Med. 14 (1993) 633-642.
    • (1993) Free Radic. Biol. Med. , vol.14 , pp. 633-642
    • Bondy, S.C.1    LeBel, C.P.2
  • 7
    • 0025344617 scopus 로고
    • A randomized, controlled trial of methylprednisolone or naloxone in the treatment of acute spinal-cord injury. Results of the Second National Acute Spinal Cord Injury Study
    • M.B. Bracken, M.J. Shepard, W.F. Collins, T.R. Holford, W. Young, D.S. Baskin, H.M. Eisenberg, E. Flamm, L. Leo-Summers, J. Maroon et al., A randomized, controlled trial of methylprednisolone or naloxone in the treatment of acute spinal-cord injury. Results of the Second National Acute Spinal Cord Injury Study, N. Engl. J. Med. 322 (1990) 1405-1411.
    • (1990) N. Engl. J. Med. , vol.322 , pp. 1405-1411
    • Bracken, M.B.1    Shepard, M.J.2    Collins, W.F.3    Holford, T.R.4    Young, W.5    Baskin, D.S.6    Eisenberg, H.M.7    Flamm, E.8    Leo-Summers, L.9    Maroon, J.10
  • 8
    • 0026544582 scopus 로고
    • Involvement of lipid peroxidation in CNS injury
    • J.M. Braughler, E.D. Hall, Involvement of lipid peroxidation in CNS injury, J. Neurotrauma 9 (Suppl. 1) (1992) S1-7.
    • (1992) J. Neurotrauma , vol.9 , Issue.SUPPL. 1
    • Braughler, J.M.1    Hall, E.D.2
  • 9
    • 0023203728 scopus 로고
    • Evaluation of an intensive methylprednisolone sodium succinate dosing regimen in experimental spinal cord injury
    • J.M. Braughler, E.D. Hall, E.D. Means, T.R. Waters, D.K. Anderson, Evaluation of an intensive methylprednisolone sodium succinate dosing regimen in experimental spinal cord injury, J. Neurosurg. 67 (1987) 102-105.
    • (1987) J. Neurosurg. , vol.67 , pp. 102-105
    • Braughler, J.M.1    Hall, E.D.2    Means, E.D.3    Waters, T.R.4    Anderson, D.K.5
  • 10
    • 0026619299 scopus 로고
    • Prevention of post-traumatic excitotoxic brain damage with NMDA antagonist drugs: A new strategy for the nineties
    • R. Bullock, Y. Kuroda, G.M. Teasdale, J. McCulloch, Prevention of post-traumatic excitotoxic brain damage with NMDA antagonist drugs: a new strategy for the nineties, Acta Neurochir. Suppl. (Wien) 55 (1992) 49-55.
    • (1992) Acta Neurochir. Suppl. (Wien) , vol.55 , pp. 49-55
    • Bullock, R.1    Kuroda, Y.2    Teasdale, G.M.3    McCulloch, J.4
  • 11
    • 0030598948 scopus 로고    scopus 로고
    • Long term treatment with (-)-deprenyl reduces the optimal dose as well as the effective dose range for increasing antioxidant enzyme activities in old mouse brain
    • M.C. Carrillo, K. Kitani, S. Kanai, Y. Sato, G.O. Ivy, K. Miyasaka, Long term treatment with (-)-deprenyl reduces the optimal dose as well as the effective dose range for increasing antioxidant enzyme activities in old mouse brain, Life Sci. 59 (1996) 1047-1057.
    • (1996) Life Sci. , vol.59 , pp. 1047-1057
    • Carrillo, M.C.1    Kitani, K.2    Kanai, S.3    Sato, Y.4    Ivy, G.O.5    Miyasaka, K.6
  • 12
    • 0026647358 scopus 로고
    • Antioxidant-dependent amelioration of brain injury: Role of CuZn-superoxidedismutase
    • P.H. Chan, Antioxidant-dependent amelioration of brain injury: role of CuZn-superoxidedismutase, J. Neurotrauma 9 (Suppl. 2) (1992) S417-S423.
    • (1992) J. Neurotrauma , vol.9 , Issue.SUPPL. 2
    • Chan, P.H.1
  • 14
    • 0023137252 scopus 로고
    • Ionic dependence of glutamate neurotoxicity
    • D. Choi, Ionic dependence of glutamate neurotoxicity, J. Neurosci. 7 (1987) 369-379.
    • (1987) J. Neurosci. , vol.7 , pp. 369-379
    • Choi, D.1
  • 15
    • 0027954265 scopus 로고
    • The effects of methylprednisolone and the ganglioside GM1 on acute spinal cord injury in rats
    • S. Constantini, W. Young, The effects of methylprednisolone and the ganglioside GM1 on acute spinal cord injury in rats, J. Neurosurg. 80 (1994) 97-111.
    • (1994) J. Neurosurg. , vol.80 , pp. 97-111
    • Constantini, S.1    Young, W.2
  • 16
    • 0030008445 scopus 로고    scopus 로고
    • Role of antioxidants in the nitric oxide-elicited inhibition of dopamine uptake in cultured mesencephalic neurons. Insights into potential mechanisms of nitric oxide-mediated neurotoxicity
    • J. Cook, D. Wink, V. Blount, M. Krishna, I. Hanbauer, Role of antioxidants in the nitric oxide-elicited inhibition of dopamine uptake in cultured mesencephalic neurons. Insights into potential mechanisms of nitric oxide-mediated neurotoxicity, Neurochem. Int. 28 (1996) 609-617.
    • (1996) Neurochem. Int. , vol.28 , pp. 609-617
    • Cook, J.1    Wink, D.2    Blount, V.3    Krishna, M.4    Hanbauer, I.5
  • 17
    • 0027686249 scopus 로고
    • Oxidative stress, glutamate, and neurodegenerative disorders
    • J. Coyle, P. Puttfarcken, Oxidative stress, glutamate, and neurodegenerative disorders, Science 262 (1993) 689-695.
    • (1993) Science , vol.262 , pp. 689-695
    • Coyle, J.1    Puttfarcken, P.2
  • 19
    • 0027933701 scopus 로고
    • +: Implications for neurodegeneration
    • +: implications for neurodegeneration, J. Neurochem. 63 (1994) 584-591.
    • (1994) J. Neurochem. , vol.63 , pp. 584-591
    • Dykens, J.A.1
  • 20
    • 0028849421 scopus 로고
    • Glutathione determination by the Tietz enzymatic recycling assay and its relationship to cellular radiation response
    • J. Eady, T. Orta, M. Dennis, M. Stratford, J. Peacock, Glutathione determination by the Tietz enzymatic recycling assay and its relationship to cellular radiation response, Br. J. Cancer 72 (1995) 1089-1095.
    • (1995) Br. J. Cancer , vol.72 , pp. 1089-1095
    • Eady, J.1    Orta, T.2    Dennis, M.3    Stratford, M.4    Peacock, J.5
  • 21
    • 0027265381 scopus 로고
    • Free radicals in brain metabolism and pathology
    • P.H. Evans, Free radicals in brain metabolism and pathology, Br. Med. Bull. 49 (1993) 577-587.
    • (1993) Br. Med. Bull. , vol.49 , pp. 577-587
    • Evans, P.H.1
  • 23
    • 0026647763 scopus 로고
    • Free radical damage to protein and DNA: Mechanisms involved and relevant observations on brain undergoing oxidative stress
    • R.A. Floyd, J.M. Carney, Free radical damage to protein and DNA: mechanisms involved and relevant observations on brain undergoing oxidative stress, Ann. Neurol. 32 (Suppl.) (1992) S22-S27.
    • (1992) Ann. Neurol. , vol.32 , Issue.SUPPL.
    • Floyd, R.A.1    Carney, J.M.2
  • 24
    • 0027990369 scopus 로고
    • Modification of glucose-6-phosphate dehydrogenase by 4-hydroxy-2-nonenal
    • B. Friguet, E. Stadman, L. Szweda, Modification of glucose-6-phosphate dehydrogenase by 4-hydroxy-2-nonenal, J. Biol. Chem. 269 (1994) 21639-21643.
    • (1994) J. Biol. Chem. , vol.269 , pp. 21639-21643
    • Friguet, B.1    Stadman, E.2    Szweda, L.3
  • 25
    • 0029130550 scopus 로고
    • Glutamate release and free radical production following brain injury: Effects of posttraumatic hypothermia
    • M.Y. Globus, O. Alonso, W.D. Dietrich, R. Busto, M.D. Ginsberg, Glutamate release and free radical production following brain injury: effects of posttraumatic hypothermia, J. Neurochem. 65 (1995) 1704-1711.
    • (1995) J. Neurochem. , vol.65 , pp. 1704-1711
    • Globus, M.Y.1    Alonso, O.2    Dietrich, W.D.3    Busto, R.4    Ginsberg, M.D.5
  • 26
    • 0029924284 scopus 로고    scopus 로고
    • Estrogens attenuate and corticosterone exacerbates excitotoxicity, oxidative injury and amyloid β-peptide toxicity in hippocampal neurons
    • Y. Goodman, A. Bruce, B. Cheng, M. Mattson, Estrogens attenuate and corticosterone exacerbates excitotoxicity, oxidative injury and amyloid β-peptide toxicity in hippocampal neurons, J. Neurochem. 66 (1996) 1836-1844.
    • (1996) J. Neurochem. , vol.66 , pp. 1836-1844
    • Goodman, Y.1    Bruce, A.2    Cheng, B.3    Mattson, M.4
  • 27
    • 0026802223 scopus 로고
    • A monitored contusion model of spinal cord injury in the rat
    • J. Gruner, A monitored contusion model of spinal cord injury in the rat, J. Neurotrauma 9 (1992) 123-128.
    • (1992) J. Neurotrauma , vol.9 , pp. 123-128
    • Gruner, J.1
  • 28
    • 0028856368 scopus 로고
    • NMDA receptor activation produces concurrent generation of nitric oxide and reactive oxygen species: Implication for cell death
    • P.G. Gunasekar, A.G. Kanthasamy, J.L. Borowitz, G.E. Isom, NMDA receptor activation produces concurrent generation of nitric oxide and reactive oxygen species: implication for cell death, J. Neurochem. 65 (1995) 2016-2021.
    • (1995) J. Neurochem. , vol.65 , pp. 2016-2021
    • Gunasekar, P.G.1    Kanthasamy, A.G.2    Borowitz, J.L.3    Isom, G.E.4
  • 29
    • 0024438217 scopus 로고
    • Free radicals and CNS injury
    • E.D. Hall, Free radicals and CNS injury, Crit. Care Clin. 5 (1989) 793-805.
    • (1989) Crit. Care Clin. , vol.5 , pp. 793-805
    • Hall, E.D.1
  • 30
    • 0027301060 scopus 로고
    • Lipid antioxidants in acute central nervous system injury
    • E.D. Hall, Lipid antioxidants in acute central nervous system injury, Ann. Emerg. Med. 22 (1993) 1022-1027.
    • (1993) Ann. Emerg. Med. , vol.22 , pp. 1022-1027
    • Hall, E.D.1
  • 31
    • 0027365090 scopus 로고
    • Neuroprotective actions of glucocorticoid and nonglucocorticoid steroids in acute neuronal injury
    • E.D. Hall, Neuroprotective actions of glucocorticoid and nonglucocorticoid steroids in acute neuronal injury, Cell Mol. Neurobiol. 13 (1993) 415-432.
    • (1993) Cell Mol. Neurobiol. , vol.13 , pp. 415-432
    • Hall, E.D.1
  • 32
    • 0024589421 scopus 로고
    • Central nervous system trauma and stoke II. Physiological and pharmacological evidence for involvement of oxygen radicals and lipid peroxidation
    • E.D. Hall, J.M. Braughler, Central nervous system trauma and stoke II. Physiological and pharmacological evidence for involvement of oxygen radicals and lipid peroxidation, Free Radic. Biol. Med. 6 (1989) 303-313.
    • (1989) Free Radic. Biol. Med. , vol.6 , pp. 303-313
    • Hall, E.D.1    Braughler, J.M.2
  • 33
    • 0026754574 scopus 로고
    • Reactive oxygen species and the central nervous system
    • B. Halliwell, Reactive oxygen species and the central nervous system, J. Neurochem. 59 (1992) 1609-1623.
    • (1992) J. Neurochem. , vol.59 , pp. 1609-1623
    • Halliwell, B.1
  • 34
    • 0027300736 scopus 로고
    • Lipid peroxidation: Its mechanism, measurement, and significance
    • discussion 724S-725S
    • B. Halliwell, S. Chirico, Lipid peroxidation: its mechanism, measurement, and significance, Am. J. Clin. Nutr. 57 (1993) 715S-724S, discussion 724S-725S.
    • (1993) Am. J. Clin. Nutr. , vol.57
    • Halliwell, B.1    Chirico, S.2
  • 35
    • 17544394927 scopus 로고
    • β-Amyloid inhibition of MTT reduction is not mimicked by inhibitors of mitochondrial respiration
    • S.R. Hawtin, A.C. Dobbins, V.J. Tailor, M.S. Shearman, β-Amyloid inhibition of MTT reduction is not mimicked by inhibitors of mitochondrial respiration, Biochem. Soc. Trans. 23 (1995) 56S.
    • (1995) Biochem. Soc. Trans. , vol.23
    • Hawtin, S.R.1    Dobbins, A.C.2    Tailor, V.J.3    Shearman, M.S.4
  • 36
    • 0026518645 scopus 로고
    • Neurotransmitter mediated mechanisms of traumatic brain injury: Acetylcholine and excitatory amino acids
    • R. Hayes, L. Jenkin, B. Lyeth, Neurotransmitter mediated mechanisms of traumatic brain injury: acetylcholine and excitatory amino acids, J. Neurotrauma 9 (1992) 173-187.
    • (1992) J. Neurotrauma , vol.9 , pp. 173-187
    • Hayes, R.1    Jenkin, L.2    Lyeth, B.3
  • 37
    • 0027430156 scopus 로고
    • Dihyrorhodamine 123: A fluorescence probe for superoxide generation?
    • L. Henderson, J. Chappell, Dihyrorhodamine 123: a fluorescence probe for superoxide generation?, Eur. J. Biochem. 217 (1993) 273-280.
    • (1993) Eur. J. Biochem. , vol.217 , pp. 273-280
    • Henderson, L.1    Chappell, J.2
  • 38
    • 0018436997 scopus 로고
    • Effects of superoxide radicals on transport (Na + K)-adenosine triphosphatase and protection by superoxide dismutase
    • T. Hexum, R. Fried, Effects of superoxide radicals on transport (Na + K)-adenosine triphosphatase and protection by superoxide dismutase, Neurochem. Res. 4 (1979) 73-82.
    • (1979) Neurochem. Res. , vol.4 , pp. 73-82
    • Hexum, T.1    Fried, R.2
  • 39
    • 0026510199 scopus 로고
    • Efficacy of the 21-aminosteroid U74006F in improving neurological recovery after spinal cord injury in rats. A possible new reflex pathway for micturition after spinal cord injury
    • A. Holtz, B. Gerdin, C.G. Xiao, C.J. Godec, Efficacy of the 21-aminosteroid U74006F in improving neurological recovery after spinal cord injury in rats. A possible new reflex pathway for micturition after spinal cord injury, Neurol. Res. 14 (1992) 49-52.
    • (1992) Neurol. Res. , vol.14 , pp. 49-52
    • Holtz, A.1    Gerdin, B.2    Xiao, C.G.3    Godec, C.J.4
  • 43
    • 0025774025 scopus 로고
    • Calcium-dependent glutamate release concomitant with massive potassium flux during cerebral ischemia in vivo
    • Y. Katayama, T. Kawamata, T. Tamura, D. Hovda, D. Becker, T. Tsubokawa, Calcium-dependent glutamate release concomitant with massive potassium flux during cerebral ischemia in vivo, Brain Res. 558 (1991) 136-140.
    • (1991) Brain Res. , vol.558 , pp. 136-140
    • Katayama, Y.1    Kawamata, T.2    Tamura, T.3    Hovda, D.4    Becker, D.5    Tsubokawa, T.6
  • 44
    • 0030754962 scopus 로고    scopus 로고
    • 4-Hydroxynonenal, an aldehydic product of membrane lipid peroxidation, impairs glutamate transport and mitochondrial function in synaptosomes
    • in press
    • J. Keller, R. Mark, A. Bruce, E. Blanc, J. Rothstein, K. Uchida, M. Mattson, 4-Hydroxynonenal, an aldehydic product of membrane lipid peroxidation, impairs glutamate transport and mitochondrial function in synaptosomes, Neuroscience, in press.
    • Neuroscience
    • Keller, J.1    Mark, R.2    Bruce, A.3    Blanc, E.4    Rothstein, J.5    Uchida, K.6    Mattson, M.7
  • 45
    • 0026345023 scopus 로고
    • Attenuation of focal cerebral ischemic injury in transgenic mice overexpressing CuZn superoxide dismutase
    • H. Kinouchi, C.J. Epstein, T. Mizui, E. Carlson, S.F. Chen, P.H. Chan, Attenuation of focal cerebral ischemic injury in transgenic mice overexpressing CuZn superoxide dismutase, Proc. Natl. Acad. Sci. USA 88 (1991) 11158-11162.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 11158-11162
    • Kinouchi, H.1    Epstein, C.J.2    Mizui, T.3    Carlson, E.4    Chen, S.F.5    Chan, P.H.6
  • 47
    • 0024437324 scopus 로고
    • Superoxide-driven oxidation of quercetin and a simple sensitive assay for determination of superoxide dismutase
    • V.A. Kostyuk, A.I. Potapovich, Superoxide-driven oxidation of quercetin and a simple sensitive assay for determination of superoxide dismutase, Biochem. Int. 19 (1989) 1117-1124.
    • (1989) Biochem. Int. , vol.19 , pp. 1117-1124
    • Kostyuk, V.A.1    Potapovich, A.I.2
  • 48
    • 0027221998 scopus 로고
    • NMDA-dependent superoxide production and neurotoxicity
    • M., Lafon-Cazal, S. Pietri, M. Culcasi, J. Bockaert, NMDA-dependent superoxide production and neurotoxicity, Nature 364 (1989) (1993) 535-537.
    • (1989) Nature , vol.364 , pp. 535-537
    • Lafon-Cazal, M.1    Pietri, S.2    Culcasi, M.3    Bockaert, J.4
  • 49
    • 0031020476 scopus 로고    scopus 로고
    • A role for 4-hydroxynonenal, an aldehydic product of lipid peroxidation, in disruption of ion homeostasis and neuronal death induced by amyloid-beta peptide
    • R. Mark, M. Lovell, W. Markesbery, K. Uchida, M. MAttson, A role for 4-hydroxynonenal, an aldehydic product of lipid peroxidation, in disruption of ion homeostasis and neuronal death induced by amyloid-beta peptide, J. Neurochem. 68 (1997) 255-264.
    • (1997) J. Neurochem. , vol.68 , pp. 255-264
    • Mark, R.1    Lovell, M.2    Markesbery, W.3    Uchida, K.4    Mattson, M.5
  • 50
    • 85088331036 scopus 로고    scopus 로고
    • Amyloid β-peptide impairs glucose transport in hippocampal and cortical neurons: Involvement of membrane lipid peroxidation
    • in press
    • R. Mark, Z. Pang, J. Geddes, K. Uchida and M. Mattson, Amyloid β-peptide impairs glucose transport in hippocampal and cortical neurons: involvement of membrane lipid peroxidation, J. Neurosci., in press.
    • J. Neurosci.
    • Mark, R.1    Pang, Z.2    Geddes, J.3    Uchida, K.4    Mattson, M.5
  • 51
    • 0029150526 scopus 로고
    • 2+ concentration, and neurotoxicity and increase antioxidant enzyme activities in hippocampal neurons
    • 2+ concentration, and neurotoxicity and increase antioxidant enzyme activities in hippocampal neurons, J. Neurochem. 65 (1995) 1740-1751.
    • (1995) J. Neurochem. , vol.65 , pp. 1740-1751
    • Mattson, M.P.1    Lovell, M.A.2    Furukawa, K.3    Markesbery, W.R.4
  • 52
    • 0029973307 scopus 로고    scopus 로고
    • Structural and functional analogs of CuZn superoxide dismutase inhibit rat brain nitric oxide synthase by interference with the reductase (diaphorase) domain
    • B. Mayer, S. Pfeiffer, E. Leopold, J. Muller, U. Weser, K. Schmidt, Structural and functional analogs of CuZn superoxide dismutase inhibit rat brain nitric oxide synthase by interference with the reductase (diaphorase) domain, Neurosci. Lett. 209 (1996) 169-172.
    • (1996) Neurosci. Lett. , vol.209 , pp. 169-172
    • Mayer, B.1    Pfeiffer, S.2    Leopold, E.3    Muller, J.4    Weser, U.5    Schmidt, K.6
  • 53
    • 0023484339 scopus 로고
    • Lipid peroxidation and the role of oxygen radicals in CNS injury
    • J.M. McCall, J.M. Braughler, E.D. Hall, Lipid peroxidation and the role of oxygen radicals in CNS injury, Acta Anaesthesiol. Belg. 38 (1987) 373-379.
    • (1987) Acta Anaesthesiol. Belg. , vol.38 , pp. 373-379
    • McCall, J.M.1    Braughler, J.M.2    Hall, E.D.3
  • 54
    • 0023610148 scopus 로고
    • A new class of compounds for stroke and trauma: Effects of 21-aminosteroids on lipid peroxidation
    • J.M. McCall, J.M. Braughler, E.D. Hall, A new class of compounds for stroke and trauma: effects of 21-aminosteroids on lipid peroxidation, Acta Anaesthesiol. Belg. 38 (1987) 417-420.
    • (1987) Acta Anaesthesiol. Belg. , vol.38 , pp. 417-420
    • McCall, J.M.1    Braughler, J.M.2    Hall, E.D.3
  • 55
    • 0024997540 scopus 로고
    • 21-aminosteroids attenuate excitotoxic neuronal injury in cortical cell cultures
    • H. Moyner, D. Hartley, D. Choi, 21-Aminosteroids attenuate excitotoxic neuronal injury in cortical cell cultures, Neuron 5 (1990) 121-126.
    • (1990) Neuron , vol.5 , pp. 121-126
    • Moyner, H.1    Hartley, D.2    Choi, D.3
  • 57
    • 0030047543 scopus 로고    scopus 로고
    • Calcium movements in traumatic brain injury: The role of glutamate receptor-operated ion channels
    • P. Nilsson, H. Laursen, L. Hillered, A.J. Hansen, Calcium movements in traumatic brain injury: the role of glutamate receptor-operated ion channels, J. Cereb. Blood Flow Metab. 16 (1996) 262-270.
    • (1996) J. Cereb. Blood Flow Metab. , vol.16 , pp. 262-270
    • Nilsson, P.1    Laursen, H.2    Hillered, L.3    Hansen, A.J.4
  • 58
    • 0023895734 scopus 로고
    • Glutamate becomes neurotoxic via the N-methyl-D-aspartate receptor when intracellular energy levels are reduced
    • A. Novelli, J. Reilly, P. Lysko, R. Henneberry, Glutamate becomes neurotoxic via the N-methyl-D-aspartate receptor when intracellular energy levels are reduced, Brain Res. 451 (1988) 205-212.
    • (1988) Brain Res. , vol.451 , pp. 205-212
    • Novelli, A.1    Reilly, J.2    Lysko, P.3    Henneberry, R.4
  • 59
    • 0025309904 scopus 로고
    • Oxidative damage to brain proteins, loss of glutamine synthetase activity, and production of free radicals during ischemia/reperfusion-induced injury to gerbil brain
    • C.N. Oliver, P.E. Starke-Reed, E.R. Stadtman, G.J. Liu, J.M. Carney, R.A. Floyd, Oxidative damage to brain proteins, loss of glutamine synthetase activity, and production of free radicals during ischemia/reperfusion-induced injury to gerbil brain, Proc. Natl. Acad. Sci. USA 87 (1990) 5144-5147.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 5144-5147
    • Oliver, C.N.1    Starke-Reed, P.E.2    Stadtman, E.R.3    Liu, G.J.4    Carney, J.M.5    Floyd, R.A.6
  • 60
    • 0027249667 scopus 로고
    • A new fluorometric assay for cytotoxic measurements in vitro
    • B. Page, M. Page, C. Noel, A new fluorometric assay for cytotoxic measurements in vitro, Int. J. Oncol. 3 (1993) 473-476.
    • (1993) Int. J. Oncol. , vol.3 , pp. 473-476
    • Page, B.1    Page, M.2    Noel, C.3
  • 61
    • 0030052530 scopus 로고    scopus 로고
    • Requirement for superoxide in excitotoxic cell death
    • M. Patel, B. Day, J. Crapo, I. Fridovich, J. McNamara, Requirement for superoxide in excitotoxic cell death, Neuron 16 (1996) 345-355.
    • (1996) Neuron , vol.16 , pp. 345-355
    • Patel, M.1    B, D.2    Crapo, J.3    Fridovich, I.4    McNamara, J.5
  • 62
    • 0027295849 scopus 로고
    • Kainic acid-induced lipid peroxidation: Protection with butylated hydroxytoluene and U78517F in primary cultures of cerebellar granule cells
    • P. Puttfarcken, R. Getz, J. Coyle, Kainic acid-induced lipid peroxidation: protection with butylated hydroxytoluene and U78517F in primary cultures of cerebellar granule cells, Brain Res. 624 (1993) 223-232.
    • (1993) Brain Res. , vol.624 , pp. 223-232
    • Puttfarcken, P.1    Getz, R.2    Coyle, J.3
  • 63
    • 0029810095 scopus 로고    scopus 로고
    • Mitochondrial dysfunction is a primary event in glutamate neurotoxicity
    • A. Schinder, E. Olson, N. Spitzer, M. Montal, Mitochondrial dysfunction is a primary event in glutamate neurotoxicity, J. Neurosci. 16 (1996) 6125-6133.
    • (1996) J. Neurosci. , vol.16 , pp. 6125-6133
    • Schinder, A.1    Olson, E.2    Spitzer, N.3    Montal, M.4
  • 66
    • 0029122478 scopus 로고
    • Superoxide radicals play important roles in the pathogenesis of spinal cord injury
    • Y. Taoka, M. Naruo, E. Koyanagi, M. Urakado, M. Inoue, Superoxide radicals play important roles in the pathogenesis of spinal cord injury, Paraplegia 33 (1995) 450-453.
    • (1995) Paraplegia , vol.33 , pp. 450-453
    • Taoka, Y.1    Naruo, M.2    Koyanagi, E.3    Urakado, M.4    Inoue, M.5
  • 67
    • 0026326449 scopus 로고
    • Review of the secondary injury theory of acute spinal cord trauma with emphasis on vascular mechanisms
    • C. Tator, M. Fehlings, Review of the secondary injury theory of acute spinal cord trauma with emphasis on vascular mechanisms, J. Neurosurg. 75 (1991) 15-26.
    • (1991) J. Neurosurg. , vol.75 , pp. 15-26
    • Tator, C.1    Fehlings, M.2
  • 68
    • 0029095243 scopus 로고
    • 2+-mediated damage to rabbit gastric mucosal cells: Modulation by nitric oxide
    • 2+-mediated damage to rabbit gastric mucosal cells: modulation by nitric oxide, Eur. J. Pharmacol. 293 (1995) 259-266.
    • (1995) Eur. J. Pharmacol. , vol.293 , pp. 259-266
    • Tepperman, B.L.1    Soper, B.D.2
  • 69
    • 0028208495 scopus 로고
    • Glutamate uptake inhibition by oxygen free radicals in rat cortical astrocytes
    • A. Volterra, D. Trotti, C. Tromba, S. Floridi, G. Racagni, Glutamate uptake inhibition by oxygen free radicals in rat cortical astrocytes, J. Neurosci. 14 (1994) 2924-2932.
    • (1994) J. Neurosci. , vol.14 , pp. 2924-2932
    • Volterra, A.1    Trotti, D.2    Tromba, C.3    Floridi, S.4    Racagni, G.5
  • 70
    • 0029788243 scopus 로고    scopus 로고
    • Mitochondrial depolarization in glutamate-stimulated neurons: An early signal specific to excitotoxin exposure
    • R. White, I. Reynolds, Mitochondrial depolarization in glutamate-stimulated neurons: an early signal specific to excitotoxin exposure, J. Neurosci. 16 (1996) 5688-5697.
    • (1996) J. Neurosci. , vol.16 , pp. 5688-5697
    • White, R.1    Reynolds, I.2
  • 72
    • 0025290130 scopus 로고
    • Chemically induced hyopglycemia and anoxia: Relationship to glutamate receptor-mediated toxicity in retina
    • G. Zeevalk, W. Nicklas, Chemically induced hyopglycemia and anoxia: relationship to glutamate receptor-mediated toxicity in retina, J. Pharmacol. Exp. Ther. 253 (1990) 1285-1292.
    • (1990) J. Pharmacol. Exp. Ther. , vol.253 , pp. 1285-1292
    • Zeevalk, G.1    Nicklas, W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.