Specific inhibition of the JNK pathway promotes locomotor recovery and neuroprotection after mouse spinal cord injury

Neurobiology of Disease

Volumn 46, Issue 3, 2012, Pages 710-721

  Repici, Mariaelena ^a,b,f   Chen, Xiaoru ^a,b   Morel, Marie Pierre ^a,b   Doulazmi, Mohamed ^a,b   Sclip, Alessandra ^c   Cannaya, Vidjeacoumary ^a,b   Veglianese, Pietro ^c   Kraftsik, Rudolf ^d   Mariani, Jean ^a,b,e   Borsello, Tiziana ^c   Dusart, Isabelle ^a,b  

^a SORBONNE UNIVERSITÉ   (France)

^b CNRS   (France)

^c MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^d UNIVERSITY OF LAUSANNE   (Switzerland)

^e HÔPITAL CHARLES FOIX   (France)

^f UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

C jun; Caspase 3; JNK; Locomotor recovery; Neuroprotection; Spinal cord injury

Indexed keywords

CASPASE 3; D JNKI1; PROTEIN C JUN; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; CONTROLLED STUDY; DRUG MECHANISM; ENZYME INHIBITION; ERYTHROCYTE; EXTRAVASATION; LOCOMOTION; MALE; MEMBRANE PERMEABILITY; MOUSE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN PHOSPHORYLATION; SPINAL CORD INJURY; WHITE MATTER;

ANIMALS; BLOOD VESSELS; BLOTTING, WESTERN; CASPASE 3; HINDLIMB; IMAGE PROCESSING, COMPUTER-ASSISTED; IMAGING, THREE-DIMENSIONAL; IMMUNOHISTOCHEMISTRY; INJECTIONS, INTRAPERITONEAL; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LOCOMOTION; MALE; MICE; NERVE FIBERS; NEUROPROTECTIVE AGENTS; PEPTIDES; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-JUN; RECOVERY OF FUNCTION; SEROTONIN; SIGNAL TRANSDUCTION; SPINAL CORD; SPINAL CORD INJURIES;

EID: 84860839823     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2012.03.014     Document Type: Article

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