-
1
-
-
66449088641
-
Pathogen recognition and inflammatory signaling in innate immune defenses
-
Table of Contents
-
T.H. Mogensen Pathogen recognition and inflammatory signaling in innate immune defenses Clinical microbiology reviews 22 2009 240 273 Table of Contents
-
(2009)
Clinical Microbiology Reviews
, vol.22
, pp. 240-273
-
-
Mogensen, T.H.1
-
3
-
-
35348932070
-
Intracellular NOD-like receptors in host defense and disease
-
T.D. Kanneganti, M. Lamkanfi, and G. Nunez Intracellular NOD-like receptors in host defense and disease Immunity 27 2007 549 559
-
(2007)
Immunity
, vol.27
, pp. 549-559
-
-
Kanneganti, T.D.1
Lamkanfi, M.2
Nunez, G.3
-
5
-
-
84908610651
-
Macrophages sense and kill bacteria through carbon monoxide-dependent inflammasome activation
-
B. Wegiel, R. Larsen, D. Gallo, B.Y. Chin, C. Harris, P. Mannam, E. Kaczmarek, P.J. Lee, B.S. Zuckerbraun, R. Flavell, M.P. Soares, and L.E. Otterbein Macrophages sense and kill bacteria through carbon monoxide-dependent inflammasome activation The Journal of clinical investigation 124 2014 4926 4940
-
(2014)
The Journal of Clinical Investigation
, vol.124
, pp. 4926-4940
-
-
Wegiel, B.1
Larsen, R.2
Gallo, D.3
Chin, B.Y.4
Harris, C.5
Mannam, P.6
Kaczmarek, E.7
Lee, P.J.8
Zuckerbraun, B.S.9
Flavell, R.10
Soares, M.P.11
Otterbein, L.E.12
-
6
-
-
84865299726
-
PAMPs and DAMPs: Signal 0s that spur autophagy and immunity
-
D. Tang, R. Kang, C.B. Coyne, H.J. Zeh, and M.T. Lotze PAMPs and DAMPs: signal 0s that spur autophagy and immunity Immunological reviews 249 2012 158 175
-
(2012)
Immunological Reviews
, vol.249
, pp. 158-175
-
-
Tang, D.1
Kang, R.2
Coyne, C.B.3
Zeh, H.J.4
Lotze, M.T.5
-
7
-
-
84871954753
-
Plasma bacterial and mitochondrial DNA distinguish bacterial sepsis from sterile systemic inflammatory response syndrome and quantify inflammatory tissue injury in nonhuman primates
-
T. Sursal, D.J. Stearns-Kurosawa, K. Itagaki, S.Y. Oh, S. Sun, S. Kurosawa, and C.J. Hauser Plasma bacterial and mitochondrial DNA distinguish bacterial sepsis from sterile systemic inflammatory response syndrome and quantify inflammatory tissue injury in nonhuman primates Shock 39 2013 55 62
-
(2013)
Shock
, vol.39
, pp. 55-62
-
-
Sursal, T.1
Stearns-Kurosawa, D.J.2
Itagaki, K.3
Oh, S.Y.4
Sun, S.5
Kurosawa, S.6
Hauser, C.J.7
-
8
-
-
84870514546
-
ATP release and purinergic signaling: A common pathway for particle-mediated inflammasome activation
-
N. Riteau, L. Baron, B. Villeret, N. Guillou, F. Savigny, B. Ryffel, F. Rassendren, M. Le Bert, A. Gombault, and I. Couillin ATP release and purinergic signaling: a common pathway for particle-mediated inflammasome activation Cell death & disease 3 2012 e403
-
(2012)
Cell Death & Disease
, vol.3
, pp. e403
-
-
Riteau, N.1
Baron, L.2
Villeret, B.3
Guillou, N.4
Savigny, F.5
Ryffel, B.6
Rassendren, F.7
Le Bert, M.8
Gombault, A.9
Couillin, I.10
-
10
-
-
0030188587
-
Heme oxygenase-1: Function, regulation, and implication of a novel stress-inducible protein in oxidant-induced lung injury
-
A.M. Choi, and J. Alam Heme oxygenase-1: function, regulation, and implication of a novel stress-inducible protein in oxidant-induced lung injury American journal of respiratory cell and molecular biology 15 1996 9 19
-
(1996)
American Journal of Respiratory Cell and Molecular Biology
, vol.15
, pp. 9-19
-
-
Choi, A.M.1
Alam, J.2
-
11
-
-
0028941025
-
Acquired resistance to acute oxidative stress. Possible role of heme oxygenase and ferritin
-
B.A. Vogt, J. Alam, A.J. Croatt, G.M. Vercellotti, and K.A. Nath Acquired resistance to acute oxidative stress. Possible role of heme oxygenase and ferritin Laboratory investigation; a journal of technical methods and pathology 72 1995 474 483
-
(1995)
Laboratory Investigation; a Journal of Technical Methods and Pathology
, vol.72
, pp. 474-483
-
-
Vogt, B.A.1
Alam, J.2
Croatt, A.J.3
Vercellotti, G.M.4
Nath, K.A.5
-
12
-
-
77952430467
-
Nox4 is a novel inducible source of reactive oxygen species in monocytes and macrophages and mediates oxidized low density lipoprotein-induced macrophage death
-
C.F. Lee, M. Qiao, K. Schroder, Q. Zhao, and R. Asmis Nox4 is a novel inducible source of reactive oxygen species in monocytes and macrophages and mediates oxidized low density lipoprotein-induced macrophage death Circ Res 106 2010 1489 1497
-
(2010)
Circ Res
, vol.106
, pp. 1489-1497
-
-
Lee, C.F.1
Qiao, M.2
Schroder, K.3
Zhao, Q.4
Asmis, R.5
-
13
-
-
84878258476
-
Mitochondria as a source of reactive oxygen and nitrogen species: From molecular mechanisms to human health
-
T.R. Figueira, M.H. Barros, A.A. Camargo, R.F. Castilho, J.C. Ferreira, A.J. Kowaltowski, F.E. Sluse, N.C. Souza-Pinto, and A.E. Vercesi Mitochondria as a source of reactive oxygen and nitrogen species: from molecular mechanisms to human health Antioxidants & redox signaling 18 2013 2029 2074
-
(2013)
Antioxidants & Redox Signaling
, vol.18
, pp. 2029-2074
-
-
Figueira, T.R.1
Barros, M.H.2
Camargo, A.A.3
Castilho, R.F.4
Ferreira, J.C.5
Kowaltowski, A.J.6
Sluse, F.E.7
Souza-Pinto, N.C.8
Vercesi, A.E.9
-
14
-
-
84901985008
-
Reactive oxygen species activated NLRP3 inflammasomes prime environment-induced murine dry eye
-
Q. Zheng, Y. Ren, P.S. Reinach, Y. She, B. Xiao, S. Hua, J. Qu, and W. Chen Reactive oxygen species activated NLRP3 inflammasomes prime environment-induced murine dry eye Experimental eye research 125 2014 1 8
-
(2014)
Experimental Eye Research
, vol.125
, pp. 1-8
-
-
Zheng, Q.1
Ren, Y.2
Reinach, P.S.3
She, Y.4
Xiao, B.5
Hua, S.6
Qu, J.7
Chen, W.8
-
16
-
-
84903193283
-
Inflammasome activation is reactive oxygen species dependent and mediates irinotecan-induced mucositis through IL-1beta and IL-18 in mice
-
R.D. Arifa, M.F. Madeira, T.P. de Paula, R.L. Lima, L.D. Tavares, Z. Menezes-Garcia, C.T. Fagundes, M.A. Rachid, B. Ryffel, D.S. Zamboni, M.M. Teixeira, and D.G. Souza Inflammasome activation is reactive oxygen species dependent and mediates irinotecan-induced mucositis through IL-1beta and IL-18 in mice The American journal of pathology 184 2014 2023 2034
-
(2014)
The American Journal of Pathology
, vol.184
, pp. 2023-2034
-
-
Arifa, R.D.1
Madeira, M.F.2
De Paula, T.P.3
Lima, R.L.4
Tavares, L.D.5
Menezes-Garcia, Z.6
Fagundes, C.T.7
Rachid, M.A.8
Ryffel, B.9
Zamboni, D.S.10
Teixeira, M.M.11
Souza, D.G.12
-
17
-
-
84865504141
-
Sterile inflammation in the liver
-
P. Kubes, and W.Z. Mehal Sterile inflammation in the liver Gastroenterology 143 2012 1158 1172
-
(2012)
Gastroenterology
, vol.143
, pp. 1158-1172
-
-
Kubes, P.1
Mehal, W.Z.2
-
19
-
-
43249125839
-
Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
-
C. Dostert, V. Petrilli, R. Van Bruggen, C. Steele, B.T. Mossman, and J. Tschopp Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica Science 320 2008 674 677
-
(2008)
Science
, vol.320
, pp. 674-677
-
-
Dostert, C.1
Petrilli, V.2
Van Bruggen, R.3
Steele, C.4
Mossman, B.T.5
Tschopp, J.6
-
20
-
-
77951295418
-
Influenza virus activates inflammasomes via its intracellular M2 ion channel
-
T. Ichinohe, I.K. Pang, and A. Iwasaki Influenza virus activates inflammasomes via its intracellular M2 ion channel Nature immunology 11 2010 404 410
-
(2010)
Nature Immunology
, vol.11
, pp. 404-410
-
-
Ichinohe, T.1
Pang, I.K.2
Iwasaki, A.3
-
21
-
-
47849097202
-
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
-
V. Hornung, F. Bauernfeind, A. Halle, E.O. Samstad, H. Kono, K.L. Rock, K.A. Fitzgerald, and E. Latz Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization Nature immunology 9 2008 847 856
-
(2008)
Nature Immunology
, vol.9
, pp. 847-856
-
-
Hornung, V.1
Bauernfeind, F.2
Halle, A.3
Samstad, E.O.4
Kono, H.5
Rock, K.L.6
Fitzgerald, K.A.7
Latz, E.8
-
22
-
-
32944470765
-
Cryopyrin activates the inflammasome in response to toxins and ATP
-
S. Mariathasan, D.S. Weiss, K. Newton, J. McBride, K. O'Rourke, M. Roose-Girma, W.P. Lee, Y. Weinrauch, D.M. Monack, and V.M. Dixit Cryopyrin activates the inflammasome in response to toxins and ATP Nature 440 2006 228 232
-
(2006)
Nature
, vol.440
, pp. 228-232
-
-
Mariathasan, S.1
Weiss, D.S.2
Newton, K.3
McBride, J.4
O'Rourke, K.5
Roose-Girma, M.6
Lee, W.P.7
Weinrauch, Y.8
Monack, D.M.9
Dixit, V.M.10
-
23
-
-
77649179433
-
NLRP3 inflammasome activation: The convergence of multiple signalling pathways on ROS production?
-
J. Tschopp, and K. Schroder NLRP3 inflammasome activation: The convergence of multiple signalling pathways on ROS production? Nat Rev Immunol 10 2010 210 215
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 210-215
-
-
Tschopp, J.1
Schroder, K.2
-
25
-
-
77956601381
-
Inflammasome activation in NADPH oxidase defective mononuclear phagocytes from patients with chronic granulomatous disease
-
F. Meissner, R.A. Seger, D. Moshous, A. Fischer, J. Reichenbach, and A. Zychlinsky Inflammasome activation in NADPH oxidase defective mononuclear phagocytes from patients with chronic granulomatous disease Blood 116 2010 1570 1573
-
(2010)
Blood
, vol.116
, pp. 1570-1573
-
-
Meissner, F.1
Seger, R.A.2
Moshous, D.3
Fischer, A.4
Reichenbach, J.5
Zychlinsky, A.6
-
26
-
-
75649096002
-
Thioredoxin-interacting protein links oxidative stress to inflammasome activation
-
R. Zhou, A. Tardivel, B. Thorens, I. Choi, and J. Tschopp Thioredoxin-interacting protein links oxidative stress to inflammasome activation Nature immunology 11 2010 136 140
-
(2010)
Nature Immunology
, vol.11
, pp. 136-140
-
-
Zhou, R.1
Tardivel, A.2
Thorens, B.3
Choi, I.4
Tschopp, J.5
-
28
-
-
77956323967
-
The therapeutic potential of carbon monoxide
-
R. Motterlini, and L.E. Otterbein The therapeutic potential of carbon monoxide Nat Rev Drug Discov 9 2010 728 743
-
(2010)
Nat Rev Drug Discov
, vol.9
, pp. 728-743
-
-
Motterlini, R.1
Otterbein, L.E.2
-
29
-
-
34247611385
-
Cross-regulation of carbon monoxide and the adenosine A2a receptor in macrophages
-
A. Haschemi, O. Wagner, R. Marculescu, B. Wegiel, S.C. Robson, N. Gagliani, D. Gallo, J.F. Chen, F.H. Bach, and L.E. Otterbein Cross-regulation of carbon monoxide and the adenosine A2a receptor in macrophages J Immunol 178 2007 5921 5929
-
(2007)
J Immunol
, vol.178
, pp. 5921-5929
-
-
Haschemi, A.1
Wagner, O.2
Marculescu, R.3
Wegiel, B.4
Robson, S.C.5
Gagliani, N.6
Gallo, D.7
Chen, J.F.8
Bach, F.H.9
Otterbein, L.E.10
-
30
-
-
3042738395
-
Heme oxygenase-1-derived carbon monoxide protects hearts from transplant associated ischemia reperfusion injury
-
Y. Akamatsu, M. Haga, S. Tyagi, K. Yamashita, A.V. Graca-Souza, R. Ollinger, E. Czismadia, G.A. May, E. Ifedigbo, L.E. Otterbein, F.H. Bach, and M.P. Soares Heme oxygenase-1-derived carbon monoxide protects hearts from transplant associated ischemia reperfusion injury FASEB J 18 2004 771 772
-
(2004)
FASEB J
, vol.18
, pp. 771-772
-
-
Akamatsu, Y.1
Haga, M.2
Tyagi, S.3
Yamashita, K.4
Graca-Souza, A.V.5
Ollinger, R.6
Czismadia, E.7
May, G.A.8
Ifedigbo, E.9
Otterbein, L.E.10
Bach, F.H.11
Soares, M.P.12
-
31
-
-
84880923978
-
Newly described pattern recognition receptors team up against intracellular pathogens
-
P. Broz, and D.M. Monack Newly described pattern recognition receptors team up against intracellular pathogens Nature reviews. Immunology 13 2013 551 565
-
(2013)
Nature Reviews. Immunology
, vol.13
, pp. 551-565
-
-
Broz, P.1
Monack, D.M.2
-
32
-
-
84875422919
-
Effector-triggered versus pattern-triggered immunity: How animals sense pathogens
-
L.M. Stuart, N. Paquette, and L. Boyer Effector-triggered versus pattern-triggered immunity: how animals sense pathogens Nature reviews. Immunology 13 2013 199 206
-
(2013)
Nature Reviews. Immunology
, vol.13
, pp. 199-206
-
-
Stuart, L.M.1
Paquette, N.2
Boyer, L.3
-
33
-
-
0038500959
-
Toll-like receptor ligand links innate and adaptive immune responses by the production of heat-shock proteins
-
U. Kumaraguru, C.D. Pack, and B.T. Rouse Toll-like receptor ligand links innate and adaptive immune responses by the production of heat-shock proteins Journal of leukocyte biology 73 2003 574 583
-
(2003)
Journal of Leukocyte Biology
, vol.73
, pp. 574-583
-
-
Kumaraguru, U.1
Pack, C.D.2
Rouse, B.T.3
-
34
-
-
84858017083
-
Heme induces programmed necrosis on macrophages through autocrine TNF and ROS production
-
G.B. Fortes, L.S. Alves, R. de Oliveira, F.F. Dutra, D. Rodrigues, P.L. Fernandez, T. Souto-Padron, M.J. De Rosa, M. Kelliher, D. Golenbock, F.K. Chan, and M.T. Bozza Heme induces programmed necrosis on macrophages through autocrine TNF and ROS production Blood 119 2012 2368 2375
-
(2012)
Blood
, vol.119
, pp. 2368-2375
-
-
Fortes, G.B.1
Alves, L.S.2
De Oliveira, R.3
Dutra, F.F.4
Rodrigues, D.5
Fernandez, P.L.6
Souto-Padron, T.7
De Rosa, M.J.8
Kelliher, M.9
Golenbock, D.10
Chan, F.K.11
Bozza, M.T.12
-
35
-
-
78650676293
-
Dysfunction of the heme recycling system in heme oxygenase 1-deficient mice: Effects on macrophage viability and tissue iron distribution
-
G. Kovtunovych, M.A. Eckhaus, M.C. Ghosh, H. Ollivierre-Wilson, and T.A. Rouault Dysfunction of the heme recycling system in heme oxygenase 1-deficient mice: effects on macrophage viability and tissue iron distribution Blood 116 2010 6054 6062
-
(2010)
Blood
, vol.116
, pp. 6054-6062
-
-
Kovtunovych, G.1
Eckhaus, M.A.2
Ghosh, M.C.3
Ollivierre-Wilson, H.4
Rouault, T.A.5
-
36
-
-
84897440605
-
Heme oxygenase-1 derived carbon monoxide permits maturation of myeloid cells
-
B. Wegiel, A. Hedblom, M. Li, D. Gallo, E. Csizmadia, C. Harris, Z. Nemeth, B.S. Zuckerbraun, M. Soares, J.L. Persson, and L.E. Otterbein Heme oxygenase-1 derived carbon monoxide permits maturation of myeloid cells Cell death & disease 5 2014 e1139
-
(2014)
Cell Death & Disease
, vol.5
, pp. e1139
-
-
Wegiel, B.1
Hedblom, A.2
Li, M.3
Gallo, D.4
Csizmadia, E.5
Harris, C.6
Nemeth, Z.7
Zuckerbraun, B.S.8
Soares, M.9
Persson, J.L.10
Otterbein, L.E.11
-
37
-
-
0030886381
-
Heme oxygenase 1 is required for mammalian iron reutilization
-
K.D. Poss, and S. Tonegawa Heme oxygenase 1 is required for mammalian iron reutilization Proc Natl Acad Sci U S A 94 1997 10919 10924
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 10919-10924
-
-
Poss, K.D.1
Tonegawa, S.2
-
38
-
-
84894567032
-
Heme triggers TLR4 signaling leading to endothelial cell activation and vaso-occlusion in murine sickle cell disease
-
J.D. Belcher, C. Chen, J. Nguyen, L. Milbauer, F. Abdulla, A.I. Alayash, A. Smith, K.A. Nath, R.P. Hebbel, and G.M. Vercellotti Heme triggers TLR4 signaling leading to endothelial cell activation and vaso-occlusion in murine sickle cell disease Blood 123 2014 377 390
-
(2014)
Blood
, vol.123
, pp. 377-390
-
-
Belcher, J.D.1
Chen, C.2
Nguyen, J.3
Milbauer, L.4
Abdulla, F.5
Alayash, A.I.6
Smith, A.7
Nath, K.A.8
Hebbel, R.P.9
Vercellotti, G.M.10
-
39
-
-
84944395650
-
TRC8 suppresses tumorigenesis through targeting heme oxygenase-1 for ubiquitination and degradation
-
P.H. Lin, W.M. Lan, and L.Y. Chau TRC8 suppresses tumorigenesis through targeting heme oxygenase-1 for ubiquitination and degradation Oncogene 2012
-
(2012)
Oncogene
-
-
Lin, P.H.1
Lan, W.M.2
Chau, L.Y.3
-
40
-
-
84892149853
-
An Update on PYRIN Domain-Containing Pattern Recognition Receptors: From Immunity to Pathology
-
R.A. Ratsimandresy, A. Dorfleutner, and C. Stehlik An Update on PYRIN Domain-Containing Pattern Recognition Receptors: From Immunity to Pathology Frontiers in immunology 4 2013 440
-
(2013)
Frontiers in Immunology
, vol.4
, pp. 440
-
-
Ratsimandresy, R.A.1
Dorfleutner, A.2
Stehlik, C.3
-
41
-
-
1642285783
-
NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder
-
L. Agostini, F. Martinon, K. Burns, M.F. McDermott, P.N. Hawkins, and J. Tschopp NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder Immunity 20 2004 319 325
-
(2004)
Immunity
, vol.20
, pp. 319-325
-
-
Agostini, L.1
Martinon, F.2
Burns, K.3
McDermott, M.F.4
Hawkins, P.N.5
Tschopp, J.6
-
42
-
-
77749304032
-
Signaling by ROS drives inflammasome activation
-
F. Martinon Signaling by ROS drives inflammasome activation European journal of immunology 40 2010 616 619
-
(2010)
European Journal of Immunology
, vol.40
, pp. 616-619
-
-
Martinon, F.1
-
43
-
-
68349157477
-
Malarial hemozoin is a Nalp3 inflammasome activating danger signal
-
C. Dostert, G. Guarda, J.F. Romero, P. Menu, O. Gross, A. Tardivel, M.L. Suva, J.C. Stehle, M. Kopf, I. Stamenkovic, G. Corradin, and J. Tschopp Malarial hemozoin is a Nalp3 inflammasome activating danger signal PLoS One 4 2009 e6510
-
(2009)
PLoS One
, vol.4
, pp. e6510
-
-
Dostert, C.1
Guarda, G.2
Romero, J.F.3
Menu, P.4
Gross, O.5
Tardivel, A.6
Suva, M.L.7
Stehle, J.C.8
Kopf, M.9
Stamenkovic, I.10
Corradin, G.11
Tschopp, J.12
-
44
-
-
79951642032
-
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
-
K. Nakahira, J.A. Haspel, V.A. Rathinam, S.J. Lee, T. Dolinay, H.C. Lam, J.A. Englert, M. Rabinovitch, M. Cernadas, H.P. Kim, K.A. Fitzgerald, S.W. Ryter, and A.M. Choi Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome Nature immunology 12 2011 222 230
-
(2011)
Nature Immunology
, vol.12
, pp. 222-230
-
-
Nakahira, K.1
Haspel, J.A.2
Rathinam, V.A.3
Lee, S.J.4
Dolinay, T.5
Lam, H.C.6
Englert, J.A.7
Rabinovitch, M.8
Cernadas, M.9
Kim, H.P.10
Fitzgerald, K.A.11
Ryter, S.W.12
Choi, A.M.13
-
45
-
-
70049101754
-
Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases
-
M.T. Shio, S.C. Eisenbarth, M. Savaria, A.F. Vinet, M.J. Bellemare, K.W. Harder, F.S. Sutterwala, D.S. Bohle, A. Descoteaux, R.A. Flavell, and M. Olivier Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases PLoS pathogens 5 2009 e1000559
-
(2009)
PLoS Pathogens
, vol.5
, pp. e1000559
-
-
Shio, M.T.1
Eisenbarth, S.C.2
Savaria, M.3
Vinet, A.F.4
Bellemare, M.J.5
Harder, K.W.6
Sutterwala, F.S.7
Bohle, D.S.8
Descoteaux, A.9
Flavell, R.A.10
Olivier, M.11
-
46
-
-
84907546730
-
Hemolysis-induced lethality involves inflammasome activation by heme
-
F.F. Dutra, L.S. Alves, D. Rodrigues, P.L. Fernandez, R.B. de Oliveira, D.T. Golenbock, D.S. Zamboni, and M.T. Bozza Hemolysis-induced lethality involves inflammasome activation by heme Proc Natl Acad Sci U S A 111 2014 E4110 E4118
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. E4110-E4118
-
-
Dutra, F.F.1
Alves, L.S.2
Rodrigues, D.3
Fernandez, P.L.4
De Oliveira, R.B.5
Golenbock, D.T.6
Zamboni, D.S.7
Bozza, M.T.8
-
47
-
-
74049121298
-
Immunogenicity of whole-parasite vaccines against Plasmodium falciparum involves malarial hemozoin and host TLR9
-
C. Coban, Y. Igari, M. Yagi, T. Reimer, S. Koyama, T. Aoshi, K. Ohata, T. Tsukui, F. Takeshita, K. Sakurai, T. Ikegami, A. Nakagawa, T. Horii, G. Nunez, K.J. Ishii, and S. Akira Immunogenicity of whole-parasite vaccines against Plasmodium falciparum involves malarial hemozoin and host TLR9 Cell host & microbe 7 2010 50 61
-
(2010)
Cell Host & Microbe
, vol.7
, pp. 50-61
-
-
Coban, C.1
Igari, Y.2
Yagi, M.3
Reimer, T.4
Koyama, S.5
Aoshi, T.6
Ohata, K.7
Tsukui, T.8
Takeshita, F.9
Sakurai, K.10
Ikegami, T.11
Nakagawa, A.12
Horii, T.13
Nunez, G.14
Ishii, K.J.15
Akira, S.16
-
48
-
-
33846911691
-
Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9
-
P. Parroche, F.N. Lauw, N. Goutagny, E. Latz, B.G. Monks, A. Visintin, K.A. Halmen, M. Lamphier, M. Olivier, D.C. Bartholomeu, R.T. Gazzinelli, and D.T. Golenbock Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9 Proc Natl Acad Sci U S A 104 2007 1919 1924
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 1919-1924
-
-
Parroche, P.1
Lauw, F.N.2
Goutagny, N.3
Latz, E.4
Monks, B.G.5
Visintin, A.6
Halmen, K.A.7
Lamphier, M.8
Olivier, M.9
Bartholomeu, D.C.10
Gazzinelli, R.T.11
Golenbock, D.T.12
-
49
-
-
77749260601
-
Experimental cerebral malaria progresses independently of the Nlrp3 inflammasome
-
T. Reimer, M.H. Shaw, L. Franchi, C. Coban, K.J. Ishii, S. Akira, T. Horii, A. Rodriguez, and G. Nunez Experimental cerebral malaria progresses independently of the Nlrp3 inflammasome European journal of immunology 40 2010 764 769
-
(2010)
European Journal of Immunology
, vol.40
, pp. 764-769
-
-
Reimer, T.1
Shaw, M.H.2
Franchi, L.3
Coban, C.4
Ishii, K.J.5
Akira, S.6
Horii, T.7
Rodriguez, A.8
Nunez, G.9
-
50
-
-
77958023093
-
A central role for free heme in the pathogenesis of severe sepsis
-
R. Larsen, R. Gozzelino, V. Jeney, L. Tokaji, F.A. Bozza, A.M. Japiassu, D. Bonaparte, M.M. Cavalcante, A. Chora, A. Ferreira, I. Marguti, S. Cardoso, N. Sepulveda, A. Smith, and M.P. Soares A central role for free heme in the pathogenesis of severe sepsis Sci Transl Med 2 2010 51ra71
-
(2010)
Sci Transl Med
, vol.2
, pp. 51ra71
-
-
Larsen, R.1
Gozzelino, R.2
Jeney, V.3
Tokaji, L.4
Bozza, F.A.5
Japiassu, A.M.6
Bonaparte, D.7
Cavalcante, M.M.8
Chora, A.9
Ferreira, A.10
Marguti, I.11
Cardoso, S.12
Sepulveda, N.13
Smith, A.14
Soares, M.P.15
-
52
-
-
84874439878
-
Hemolysis and free hemoglobin revisited: Exploring hemoglobin and hemin scavengers as a novel class of therapeutic proteins
-
D.J. Schaer, P.W. Buehler, A.I. Alayash, J.D. Belcher, and G.M. Vercellotti Hemolysis and free hemoglobin revisited: exploring hemoglobin and hemin scavengers as a novel class of therapeutic proteins Blood 121 2013 1276 1284
-
(2013)
Blood
, vol.121
, pp. 1276-1284
-
-
Schaer, D.J.1
Buehler, P.W.2
Alayash, A.I.3
Belcher, J.D.4
Vercellotti, G.M.5
-
53
-
-
84877836304
-
CD163 and IgG codefend against cytotoxic hemoglobin via autocrine and paracrine mechanisms
-
K. Subramanian, R. Du, N.S. Tan, B. Ho, and J.L. Ding CD163 and IgG codefend against cytotoxic hemoglobin via autocrine and paracrine mechanisms J Immunol 190 2013 5267 5278
-
(2013)
J Immunol
, vol.190
, pp. 5267-5278
-
-
Subramanian, K.1
Du, R.2
Tan, N.S.3
Ho, B.4
Ding, J.L.5
-
55
-
-
0023239961
-
Acute phase protein response to tissue injury
-
W.M. Stahl Acute phase protein response to tissue injury Critical care medicine 15 1987 545 550
-
(1987)
Critical Care Medicine
, vol.15
, pp. 545-550
-
-
Stahl, W.M.1
-
56
-
-
84897513452
-
Extracellular Hb enhances cardiac toxicity in endotoxemic Guinea pigs: Protective role of haptoglobin
-
J.H. Baek, X. Zhang, M.C. Williams, D.J. Schaer, P.W. Buehler, and F. D'Agnillo Extracellular Hb enhances cardiac toxicity in endotoxemic guinea pigs: protective role of haptoglobin Toxins 6 2014 1244 1259
-
(2014)
Toxins
, vol.6
, pp. 1244-1259
-
-
Baek, J.H.1
Zhang, X.2
Williams, M.C.3
Schaer, D.J.4
Buehler, P.W.5
D'Agnillo, F.6
-
57
-
-
38949115537
-
Heme carrier protein (HCP-1) spatially interacts with the CD163 hemoglobin uptake pathway and is a target of inflammatory macrophage activation
-
C.A. Schaer, F. Vallelian, A. Imhof, G. Schoedon, and D.J. Schaer Heme carrier protein (HCP-1) spatially interacts with the CD163 hemoglobin uptake pathway and is a target of inflammatory macrophage activation Journal of leukocyte biology 83 2008 325 333
-
(2008)
Journal of Leukocyte Biology
, vol.83
, pp. 325-333
-
-
Schaer, C.A.1
Vallelian, F.2
Imhof, A.3
Schoedon, G.4
Schaer, D.J.5
-
58
-
-
79957723868
-
Iron trafficking and metabolism in macrophages: Contribution to the polarized phenotype
-
G. Cairo, S. Recalcati, A. Mantovani, and M. Locati Iron trafficking and metabolism in macrophages: contribution to the polarized phenotype Trends in immunology 32 2011 241 247
-
(2011)
Trends in Immunology
, vol.32
, pp. 241-247
-
-
Cairo, G.1
Recalcati, S.2
Mantovani, A.3
Locati, M.4
-
59
-
-
24144459870
-
Identification of an intestinal heme transporter
-
M. Shayeghi, G.O. Latunde-Dada, J.S. Oakhill, A.H. Laftah, K. Takeuchi, N. Halliday, Y. Khan, A. Warley, F.E. McCann, R.C. Hider, D.M. Frazer, G.J. Anderson, C.D. Vulpe, R.J. Simpson, and A.T. McKie Identification of an intestinal heme transporter Cell 122 2005 789 801
-
(2005)
Cell
, vol.122
, pp. 789-801
-
-
Shayeghi, M.1
Latunde-Dada, G.O.2
Oakhill, J.S.3
Laftah, A.H.4
Takeuchi, K.5
Halliday, N.6
Khan, Y.7
Warley, A.8
McCann, F.E.9
Hider, R.C.10
Frazer, D.M.11
Anderson, G.J.12
Vulpe, C.D.13
Simpson, R.J.14
McKie, A.T.15
-
60
-
-
84899942981
-
Hemopexin-dependent heme uptake via endocytosis regulates the Bach1 transcription repressor and heme oxygenase gene activation
-
H. Hada, T. Shiraki, M. Watanabe-Matsui, and K. Igarashi Hemopexin-dependent heme uptake via endocytosis regulates the Bach1 transcription repressor and heme oxygenase gene activation Biochimica et biophysica acta 1840 2014 2351 2360
-
(2014)
Biochimica et Biophysica Acta
, vol.1840
, pp. 2351-2360
-
-
Hada, H.1
Shiraki, T.2
Watanabe-Matsui, M.3
Igarashi, K.4
-
61
-
-
84908373728
-
Haptoglobin, hemopexin, and related defense pathways-basic science, clinical perspectives, and drug development
-
D.J. Schaer, F. Vinchi, G. Ingoglia, E. Tolosano, and P.W. Buehler Haptoglobin, hemopexin, and related defense pathways-basic science, clinical perspectives, and drug development Frontiers in physiology 5 2014 415
-
(2014)
Frontiers in Physiology
, vol.5
, pp. 415
-
-
Schaer, D.J.1
Vinchi, F.2
Ingoglia, G.3
Tolosano, E.4
Buehler, P.W.5
-
62
-
-
0017936829
-
Abnormal heme-protein patterns in hemorrhagic shock
-
Z. Friedman-Mor, J. Chalon, F. Gorstein, H. Turndorf, J.V. Chuba, and L.R. Orkin Abnormal heme-protein patterns in hemorrhagic shock The Journal of trauma 18 1978 104 107
-
(1978)
The Journal of Trauma
, vol.18
, pp. 104-107
-
-
Friedman-Mor, Z.1
Chalon, J.2
Gorstein, F.3
Turndorf, H.4
Chuba, J.V.5
Orkin, L.R.6
-
63
-
-
84905089416
-
Phagocytic uptake of oxidized heme polymer is highly cytotoxic to macrophages
-
R. Deshmukh, and V. Trivedi Phagocytic uptake of oxidized heme polymer is highly cytotoxic to macrophages PloS one 9 2014 e103706
-
(2014)
PloS One
, vol.9
, pp. e103706
-
-
Deshmukh, R.1
Trivedi, V.2
-
64
-
-
77953788926
-
Mitochondrial peptides are potent immune activators that activate human neutrophils via FPR-1
-
discussion 1332-1324
-
M. Raoof, Q. Zhang, K. Itagaki, and C.J. Hauser Mitochondrial peptides are potent immune activators that activate human neutrophils via FPR-1 J Trauma 68 2010 1328 1332 discussion 1332-1324
-
(2010)
J Trauma
, vol.68
, pp. 1328-1332
-
-
Raoof, M.1
Zhang, Q.2
Itagaki, K.3
Hauser, C.J.4
-
65
-
-
84871326101
-
Stimulated human mast cells secrete mitochondrial components that have autocrine and paracrine inflammatory actions
-
B. Zhang, S. Asadi, Z. Weng, N. Sismanopoulos, and T.C. Theoharides Stimulated human mast cells secrete mitochondrial components that have autocrine and paracrine inflammatory actions PloS one 7 2012 e49767
-
(2012)
PloS One
, vol.7
, pp. e49767
-
-
Zhang, B.1
Asadi, S.2
Weng, Z.3
Sismanopoulos, N.4
Theoharides, T.C.5
-
66
-
-
84883785469
-
The dendritic cell response to classic, emerging, and homeostatic danger signals. Implications for autoimmunity
-
P.M. Gallo, and S. Gallucci The dendritic cell response to classic, emerging, and homeostatic danger signals. Implications for autoimmunity Frontiers in immunology 4 2013 138
-
(2013)
Frontiers in Immunology
, vol.4
, pp. 138
-
-
Gallo, P.M.1
Gallucci, S.2
-
67
-
-
84905503923
-
Mitochondria released by cells undergoing TNF-alpha-induced necroptosis act as danger signals
-
A. Maeda, and B. Fadeel Mitochondria released by cells undergoing TNF-alpha-induced necroptosis act as danger signals Cell death & disease 5 2014 e1312
-
(2014)
Cell Death & Disease
, vol.5
, pp. e1312
-
-
Maeda, A.1
Fadeel, B.2
-
69
-
-
33846898975
-
Toll-like receptor 9 acts at an early stage in host defence against pneumococcal infection
-
B. Albiger, S. Dahlberg, A. Sandgren, F. Wartha, K. Beiter, H. Katsuragi, S. Akira, S. Normark, and B. Henriques-Normark Toll-like receptor 9 acts at an early stage in host defence against pneumococcal infection Cellular microbiology 9 2007 633 644
-
(2007)
Cellular Microbiology
, vol.9
, pp. 633-644
-
-
Albiger, B.1
Dahlberg, S.2
Sandgren, A.3
Wartha, F.4
Beiter, K.5
Katsuragi, H.6
Akira, S.7
Normark, S.8
Henriques-Normark, B.9
-
70
-
-
77950275298
-
Circulating mitochondrial DAMPs cause inflammatory responses to injury
-
Q. Zhang, M. Raoof, Y. Chen, Y. Sumi, T. Sursal, W. Junger, K. Brohi, K. Itagaki, and C.J. Hauser Circulating mitochondrial DAMPs cause inflammatory responses to injury Nature 464 2010 104 107
-
(2010)
Nature
, vol.464
, pp. 104-107
-
-
Zhang, Q.1
Raoof, M.2
Chen, Y.3
Sumi, Y.4
Sursal, T.5
Junger, W.6
Brohi, K.7
Itagaki, K.8
Hauser, C.J.9
-
71
-
-
0042847262
-
Macrophages of the splenic marginal zone are essential for trapping of blood-borne particulate antigen but dispensable for induction of specific T cell responses
-
P. Aichele, J. Zinke, L. Grode, R.A. Schwendener, S.H. Kaufmann, and P. Seiler Macrophages of the splenic marginal zone are essential for trapping of blood-borne particulate antigen but dispensable for induction of specific T cell responses J Immunol 171 2003 1148 1155
-
(2003)
J Immunol
, vol.171
, pp. 1148-1155
-
-
Aichele, P.1
Zinke, J.2
Grode, L.3
Schwendener, R.A.4
Kaufmann, S.H.5
Seiler, P.6
-
72
-
-
34548857335
-
Inside, outside, upside down: Damage-associated molecular-pattern molecules (DAMPs) and redox
-
A. Rubartelli, and M.T. Lotze Inside, outside, upside down: damage-associated molecular-pattern molecules (DAMPs) and redox Trends in immunology 28 2007 429 436
-
(2007)
Trends in Immunology
, vol.28
, pp. 429-436
-
-
Rubartelli, A.1
Lotze, M.T.2
-
73
-
-
84875864680
-
Patients with idiopathic pulmonary fibrosis with antibodies to heat shock protein 70 have poor prognoses
-
R.A. Kahloon, J. Xue, A. Bhargava, E. Csizmadia, L. Otterbein, D.J. Kass, J. Bon, M. Soejima, M.C. Levesque, K.O. Lindell, K.F. Gibson, N. Kaminski, G. Banga, C.V. Oddis, J.M. Pilewski, F.C. Sciurba, M. Donahoe, Y. Zhang, and S.R. Duncan Patients with idiopathic pulmonary fibrosis with antibodies to heat shock protein 70 have poor prognoses American journal of respiratory and critical care medicine 187 2013 768 775
-
(2013)
American Journal of Respiratory and Critical Care Medicine
, vol.187
, pp. 768-775
-
-
Kahloon, R.A.1
Xue, J.2
Bhargava, A.3
Csizmadia, E.4
Otterbein, L.5
Kass, D.J.6
Bon, J.7
Soejima, M.8
Levesque, M.C.9
Lindell, K.O.10
Gibson, K.F.11
Kaminski, N.12
Banga, G.13
Oddis, C.V.14
Pilewski, J.M.15
Sciurba, F.C.16
Donahoe, M.17
Zhang, Y.18
Duncan, S.R.19
-
74
-
-
26644447615
-
Phagosome maturation proceeds independently of stimulation of toll-like receptors 2 and 4
-
R.M. Yates, and D.G. Russell Phagosome maturation proceeds independently of stimulation of toll-like receptors 2 and 4 Immunity 23 2005 409 417
-
(2005)
Immunity
, vol.23
, pp. 409-417
-
-
Yates, R.M.1
Russell, D.G.2
-
75
-
-
84878245034
-
Activation of caspase-1 by the NLRP3 inflammasome regulates the NADPH oxidase NOX2 to control phagosome function
-
A. Sokolovska, C.E. Becker, W.K. Ip, V.A. Rathinam, M. Brudner, N. Paquette, A. Tanne, S.K. Vanaja, K.J. Moore, K.A. Fitzgerald, A. Lacy-Hulbert, and L.M. Stuart Activation of caspase-1 by the NLRP3 inflammasome regulates the NADPH oxidase NOX2 to control phagosome function Nature immunology 14 2013 543 553
-
(2013)
Nature Immunology
, vol.14
, pp. 543-553
-
-
Sokolovska, A.1
Becker, C.E.2
Ip, W.K.3
Rathinam, V.A.4
Brudner, M.5
Paquette, N.6
Tanne, A.7
Vanaja, S.K.8
Moore, K.J.9
Fitzgerald, K.A.10
Lacy-Hulbert, A.11
Stuart, L.M.12
-
76
-
-
84871188736
-
Nitric oxide controls the immunopathology of tuberculosis by inhibiting NLRP3 inflammasome-dependent processing of IL-1beta
-
B.B. Mishra, V.A. Rathinam, G.W. Martens, A.J. Martinot, H. Kornfeld, K.A. Fitzgerald, and C.M. Sassetti Nitric oxide controls the immunopathology of tuberculosis by inhibiting NLRP3 inflammasome-dependent processing of IL-1beta Nature immunology 14 2013 52 60
-
(2013)
Nature Immunology
, vol.14
, pp. 52-60
-
-
Mishra, B.B.1
Rathinam, V.A.2
Martens, G.W.3
Martinot, A.J.4
Kornfeld, H.5
Fitzgerald, K.A.6
Sassetti, C.M.7
-
77
-
-
76349103022
-
Nitric oxide-dependent bone marrow progenitor mobilization by carbon monoxide enhances endothelial repair after vascular injury
-
B. Wegiel, D.J. Gallo, K.G. Raman, J.M. Karlsson, B. Ozanich, B.Y. Chin, E. Tzeng, S. Ahmad, A. Ahmed, C.J. Baty, and L.E. Otterbein Nitric oxide-dependent bone marrow progenitor mobilization by carbon monoxide enhances endothelial repair after vascular injury Circulation 121 2010 537 548
-
(2010)
Circulation
, vol.121
, pp. 537-548
-
-
Wegiel, B.1
Gallo, D.J.2
Raman, K.G.3
Karlsson, J.M.4
Ozanich, B.5
Chin, B.Y.6
Tzeng, E.7
Ahmad, S.8
Ahmed, A.9
Baty, C.J.10
Otterbein, L.E.11
-
78
-
-
0344737602
-
Carbon monoxide protects against liver failure through nitric oxide-induced heme oxygenase 1
-
B.S. Zuckerbraun, T.R. Billiar, S.L. Otterbein, P.K. Kim, F. Liu, A.M. Choi, F.H. Bach, and L.E. Otterbein Carbon monoxide protects against liver failure through nitric oxide-induced heme oxygenase 1 The Journal of experimental medicine 198 2003 1707 1716
-
(2003)
The Journal of Experimental Medicine
, vol.198
, pp. 1707-1716
-
-
Zuckerbraun, B.S.1
Billiar, T.R.2
Otterbein, S.L.3
Kim, P.K.4
Liu, F.5
Choi, A.M.6
Bach, F.H.7
Otterbein, L.E.8
-
79
-
-
0028934533
-
Regulation and functions of nitric oxide in the liver in sepsis and inflammation
-
C.M. Pastor, and T.R. Billiar Regulation and functions of nitric oxide in the liver in sepsis and inflammation New Horiz 3 1995 65 72
-
(1995)
New Horiz
, vol.3
, pp. 65-72
-
-
Pastor, C.M.1
Billiar, T.R.2
-
80
-
-
0032038632
-
Chlamydial infection in inducible nitric oxide synthase knockout mice
-
J.U. Igietseme, L.L. Perry, G.A. Ananaba, I.M. Uriri, O.O. Ojior, S.N. Kumar, and H.D. Caldwell Chlamydial infection in inducible nitric oxide synthase knockout mice Infection and immunity 66 1998 1282 1286
-
(1998)
Infection and Immunity
, vol.66
, pp. 1282-1286
-
-
Igietseme, J.U.1
Perry, L.L.2
Ananaba, G.A.3
Uriri, I.M.4
Ojior, O.O.5
Kumar, S.N.6
Caldwell, H.D.7
-
81
-
-
38149008232
-
Heme oxygenase-1-derived carbon monoxide enhances the host defense response to microbial sepsis in mice
-
S.W. Chung, X. Liu, A.A. Macias, R.M. Baron, and M.A. Perrella Heme oxygenase-1-derived carbon monoxide enhances the host defense response to microbial sepsis in mice The Journal of clinical investigation 118 2008 239 247
-
(2008)
The Journal of Clinical Investigation
, vol.118
, pp. 239-247
-
-
Chung, S.W.1
Liu, X.2
Macias, A.A.3
Baron, R.M.4
Perrella, M.A.5
-
83
-
-
84868198183
-
Gene polymorphisms in the heme degradation pathway and outcome of severe human sepsis
-
C. Sponholz, K. Huse, M. Kramer, E.J. Giamarellos-Bourboulis, R.A. Claus, A. Kern, C. Engel, E. Kuhnt, M. Kiehntopf, C. Routsi, V. Mylona, I. Tsangaris, S.H. Heinemann, K. Reinhart, M. Platzer, and M. Bauer Gene polymorphisms in the heme degradation pathway and outcome of severe human sepsis Shock 38 2012 459 465
-
(2012)
Shock
, vol.38
, pp. 459-465
-
-
Sponholz, C.1
Huse, K.2
Kramer, M.3
Giamarellos-Bourboulis, E.J.4
Claus, R.A.5
Kern, A.6
Engel, C.7
Kuhnt, E.8
Kiehntopf, M.9
Routsi, C.10
Mylona, V.11
Tsangaris, I.12
Heinemann, S.H.13
Reinhart, K.14
Platzer, M.15
Bauer, M.16
-
85
-
-
84878535419
-
Protection from age-related increase in lipid biomarkers and inflammation contributes to cardiovascular protection in Gilbert's syndrome
-
M. Wallner, R. Marculescu, D. Doberer, M. Wolzt, O. Wagner, L. Vitek, A.C. Bulmer, and K.H. Wagner Protection from age-related increase in lipid biomarkers and inflammation contributes to cardiovascular protection in Gilbert's syndrome Clin Sci (Lond) 125 2013 257 264
-
(2013)
Clin Sci (Lond)
, vol.125
, pp. 257-264
-
-
Wallner, M.1
Marculescu, R.2
Doberer, D.3
Wolzt, M.4
Wagner, O.5
Vitek, L.6
Bulmer, A.C.7
Wagner, K.H.8
-
86
-
-
81755186976
-
Biliverdin inhibits Toll-like receptor-4 (TLR4) expression through nitric oxide-dependent nuclear translocation of biliverdin reductase
-
B. Wegiel, D. Gallo, E. Csizmadia, T. Roger, E. Kaczmarek, C. Harris, B.S. Zuckerbraun, and L.E. Otterbein Biliverdin inhibits Toll-like receptor-4 (TLR4) expression through nitric oxide-dependent nuclear translocation of biliverdin reductase Proc Natl Acad Sci U S A 108 2011 18849 18854
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 18849-18854
-
-
Wegiel, B.1
Gallo, D.2
Csizmadia, E.3
Roger, T.4
Kaczmarek, E.5
Harris, C.6
Zuckerbraun, B.S.7
Otterbein, L.E.8
-
87
-
-
27744592135
-
Bilirubin decreases nos2 expression via inhibition of NAD(P)H oxidase: Implications for protection against endotoxic shock in rats
-
S. Lanone, S. Bloc, R. Foresti, A. Almolki, C. Taille, J. Callebert, M. Conti, D. Goven, M. Aubier, B. Dureuil, J. El-Benna, R. Motterlini, and J. Boczkowski Bilirubin decreases nos2 expression via inhibition of NAD(P)H oxidase: implications for protection against endotoxic shock in rats FASEB J 19 2005 1890 1892
-
(2005)
FASEB J
, vol.19
, pp. 1890-1892
-
-
Lanone, S.1
Bloc, S.2
Foresti, R.3
Almolki, A.4
Taille, C.5
Callebert, J.6
Conti, M.7
Goven, D.8
Aubier, M.9
Dureuil, B.10
El-Benna, J.11
Motterlini, R.12
Boczkowski, J.13
-
88
-
-
17444423274
-
Heme oxygenase-1-generated biliverdin ameliorates experimental murine colitis
-
P.O. Berberat, A.R. YI, K. Yamashita, M.M. Warny, E. Csizmadia, S.C. Robson, and F.H. Bach Heme oxygenase-1-generated biliverdin ameliorates experimental murine colitis Inflammatory bowel diseases 11 2005 350 359
-
(2005)
Inflammatory Bowel Diseases
, vol.11
, pp. 350-359
-
-
Berberat, P.O.1
Yi, A.R.2
Yamashita, K.3
Warny, M.M.4
Csizmadia, E.5
Robson, S.C.6
Bach, F.H.7
-
89
-
-
84880776970
-
Biliverdin protects against liver ischemia reperfusion injury in swine
-
B. Andria, A. Bracco, C. Attanasio, S. Castaldo, M.G. Cerrito, S. Cozzolino, D. Di Napoli, R. Giovannoni, A. Mancini, A. Musumeci, E. Mezza, M. Nasti, V. Scuderi, S. Staibano, M. Lavitrano, L.E. Otterbein, and F. Calise Biliverdin protects against liver ischemia reperfusion injury in swine PloS one 8 2013 e69972
-
(2013)
PloS One
, vol.8
, pp. e69972
-
-
Andria, B.1
Bracco, A.2
Attanasio, C.3
Castaldo, S.4
Cerrito, M.G.5
Cozzolino, S.6
Di Napoli, D.7
Giovannoni, R.8
Mancini, A.9
Musumeci, A.10
Mezza, E.11
Nasti, M.12
Scuderi, V.13
Staibano, S.14
Lavitrano, M.15
Otterbein, L.E.16
Calise, F.17
-
90
-
-
69249110030
-
Cell surface biliverdin reductase mediates biliverdin-induced anti-inflammatory effects via phosphatidylinositol 3-kinase and Akt
-
B. Wegiel, C.J. Baty, D. Gallo, E. Csizmadia, J.R. Scott, A. Akhavan, B.Y. Chin, E. Kaczmarek, J. Alam, F.H. Bach, B.S. Zuckerbraun, and L.E. Otterbein Cell surface biliverdin reductase mediates biliverdin-induced anti-inflammatory effects via phosphatidylinositol 3-kinase and Akt The Journal of biological chemistry 284 2009 21369 21378
-
(2009)
The Journal of Biological Chemistry
, vol.284
, pp. 21369-21378
-
-
Wegiel, B.1
Baty, C.J.2
Gallo, D.3
Csizmadia, E.4
Scott, J.R.5
Akhavan, A.6
Chin, B.Y.7
Kaczmarek, E.8
Alam, J.9
Bach, F.H.10
Zuckerbraun, B.S.11
Otterbein, L.E.12
-
91
-
-
0023132858
-
Bilirubin is an antioxidant of possible physiological importance
-
R. Stocker, Y. Yamamoto, A.F. McDonagh, A.N. Glazer, and B.N. Ames Bilirubin is an antioxidant of possible physiological importance Science 235 1987 1043 1046
-
(1987)
Science
, vol.235
, pp. 1043-1046
-
-
Stocker, R.1
Yamamoto, Y.2
McDonagh, A.F.3
Glazer, A.N.4
Ames, B.N.5
-
92
-
-
84945285459
-
Bilirubin scavenges chloramines and inhibits myeloperoxidase induced protein/lipid oxidation in physiologically relevant hyperbilirubinaemic serum
-
A.C. Boon, C.L. Hawkins, J.S. Coombes, K.H. Wagner, and A.C. Bulmer Bilirubin scavenges chloramines and inhibits myeloperoxidase induced protein/lipid oxidation in physiologically relevant hyperbilirubinaemic serum Free Radic Biol Med 2015
-
(2015)
Free Radic Biol Med
-
-
Boon, A.C.1
Hawkins, C.L.2
Coombes, J.S.3
Wagner, K.H.4
Bulmer, A.C.5
-
93
-
-
70350351419
-
Limited role for the bilirubin-biliverdin redox amplification cycle in the cellular antioxidant protection by biliverdin reductase
-
G.J. Maghzal, M.C. Leck, E. Collinson, C. Li, and R. Stocker Limited role for the bilirubin-biliverdin redox amplification cycle in the cellular antioxidant protection by biliverdin reductase The Journal of biological chemistry 284 2009 29251 29259
-
(2009)
The Journal of Biological Chemistry
, vol.284
, pp. 29251-29259
-
-
Maghzal, G.J.1
Leck, M.C.2
Collinson, E.3
Li, C.4
Stocker, R.5
-
94
-
-
65249123179
-
Bilirubin and glutathione have complementary antioxidant and cytoprotective roles
-
T.W. Sedlak, M. Saleh, D.S. Higginson, B.D. Paul, K.R. Juluri, and S.H. Snyder Bilirubin and glutathione have complementary antioxidant and cytoprotective roles Proc Natl Acad Sci U S A 106 2009 5171 5176
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 5171-5176
-
-
Sedlak, T.W.1
Saleh, M.2
Higginson, D.S.3
Paul, B.D.4
Juluri, K.R.5
Snyder, S.H.6
-
95
-
-
33645048994
-
Cellular regulation and molecular interactions of the ferritins
-
K.J. Hintze, and E.C. Theil Cellular regulation and molecular interactions of the ferritins Cell Mol Life Sci 63 2006 591 600
-
(2006)
Cell Mol Life Sci
, vol.63
, pp. 591-600
-
-
Hintze, K.J.1
Theil, E.C.2
-
96
-
-
0141818109
-
Heavy chain ferritin acts as an antiapoptotic gene that protects livers from ischemia reperfusion injury
-
P.O. Berberat, M. Katori, E. Kaczmarek, D. Anselmo, C. Lassman, B. Ke, X. Shen, R.W. Busuttil, K. Yamashita, E. Csizmadia, S. Tyagi, L.E. Otterbein, S. Brouard, E. Tobiasch, F.H. Bach, J.W. Kupiec-Weglinski, and M.P. Soares Heavy chain ferritin acts as an antiapoptotic gene that protects livers from ischemia reperfusion injury FASEB J 17 2003 1724 1726
-
(2003)
FASEB J
, vol.17
, pp. 1724-1726
-
-
Berberat, P.O.1
Katori, M.2
Kaczmarek, E.3
Anselmo, D.4
Lassman, C.5
Ke, B.6
Shen, X.7
Busuttil, R.W.8
Yamashita, K.9
Csizmadia, E.10
Tyagi, S.11
Otterbein, L.E.12
Brouard, S.13
Tobiasch, E.14
Bach, F.H.15
Kupiec-Weglinski, J.W.16
Soares, M.P.17
-
98
-
-
0031714412
-
Induction of ferritin and heme oxygenase-1 by endotoxin in the lung
-
M.S. Carraway, A.J. Ghio, J.L. Taylor, and C.A. Piantadosi Induction of ferritin and heme oxygenase-1 by endotoxin in the lung Am J Physiol 275 1998 L583 L592
-
(1998)
Am J Physiol
, vol.275
, pp. L583-L592
-
-
Carraway, M.S.1
Ghio, A.J.2
Taylor, J.L.3
Piantadosi, C.A.4
-
99
-
-
33644641067
-
The mammalian cap and collar family of transcription factors
-
J. Alam The mammalian cap and collar family of transcription factors Antioxidants & redox signaling 8 2006 39 42
-
(2006)
Antioxidants & Redox Signaling
, vol.8
, pp. 39-42
-
-
Alam, J.1
-
100
-
-
0033543566
-
Nrf2, a Cap'n'Collar transcription factor, regulates induction of the heme oxygenase-1 gene
-
J. Alam, D. Stewart, C. Touchard, S. Boinapally, A.M. Choi, and J.L. Cook Nrf2, a Cap'n'Collar transcription factor, regulates induction of the heme oxygenase-1 gene The Journal of biological chemistry 274 1999 26071 26078
-
(1999)
The Journal of Biological Chemistry
, vol.274
, pp. 26071-26078
-
-
Alam, J.1
Stewart, D.2
Touchard, C.3
Boinapally, S.4
Choi, A.M.5
Cook, J.L.6
-
103
-
-
84928027734
-
The role of formylated peptides and formyl peptide receptor 1 in governing neutrophil function during acute inflammation
-
D.A. Dorward, C.D. Lucas, G.B. Chapman, C. Haslett, K. Dhaliwal, and A.G. Rossi The role of formylated peptides and formyl peptide receptor 1 in governing neutrophil function during acute inflammation Am J Pathol 185 2015 1172 1184
-
(2015)
Am J Pathol
, vol.185
, pp. 1172-1184
-
-
Dorward, D.A.1
Lucas, C.D.2
Chapman, G.B.3
Haslett, C.4
Dhaliwal, K.5
Rossi, A.G.6
-
104
-
-
79954622511
-
Free heme is a danger signal inducing expression of proinflammatory proteins in cultured cells derived from normal rat hearts
-
K. Hao, H. Hanawa, L. Ding, Y. Ota, K. Yoshida, K. Toba, M. Ogura, H. Ito, M. Kodama, and Y. Aizawa Free heme is a danger signal inducing expression of proinflammatory proteins in cultured cells derived from normal rat hearts Mol Immunol 48 2011 1191 1202
-
(2011)
Mol Immunol
, vol.48
, pp. 1191-1202
-
-
Hao, K.1
Hanawa, H.2
Ding, L.3
Ota, Y.4
Yoshida, K.5
Toba, K.6
Ogura, M.7
Ito, H.8
Kodama, M.9
Aizawa, Y.10
-
105
-
-
84873550167
-
NADPH oxidase and Nrf2 regulate gastric aspiration-induced inflammation and acute lung injury
-
B.A. Davidson, R.R. Vethanayagam, M.J. Grimm, B.A. Mullan, K. Raghavendran, T.S. Blackwell, M.L. Freeman, V. Ayyasamy, K.K. Singh, M.B. Sporn, K. Itagaki, C.J. Hauser, P.R. Knight, and B.H. Segal NADPH oxidase and Nrf2 regulate gastric aspiration-induced inflammation and acute lung injury J Immunol 190 2013 1714 1724
-
(2013)
J Immunol
, vol.190
, pp. 1714-1724
-
-
Davidson, B.A.1
Vethanayagam, R.R.2
Grimm, M.J.3
Mullan, B.A.4
Raghavendran, K.5
Blackwell, T.S.6
Freeman, M.L.7
Ayyasamy, V.8
Singh, K.K.9
Sporn, M.B.10
Itagaki, K.11
Hauser, C.J.12
Knight, P.R.13
Segal, B.H.14
-
106
-
-
60649095328
-
Heme oxygenase-1: From biology to therapeutic potential
-
M.P. Soares, and F.H. Bach Heme oxygenase-1: from biology to therapeutic potential Trends in molecular medicine 15 2009 50 58
-
(2009)
Trends in Molecular Medicine
, vol.15
, pp. 50-58
-
-
Soares, M.P.1
Bach, F.H.2
-
107
-
-
84864428068
-
M. Heme arginate improves reperfusion patterns after ischemia: A randomized, placebo-controlled trial in healthy male subjects
-
Andreas
-
Andreas M. Schmid, A.I. Doberer, D. Schewzow, K. Weisshaar, S. Heinze, G. Bilban, M. Moser, and E. Wolzt M. Heme arginate improves reperfusion patterns after ischemia: a randomized, placebo-controlled trial in healthy male subjects J Cardiovasc Magn Reson 14 2012 55
-
(2012)
J Cardiovasc Magn Reson
, vol.14
, pp. 55
-
-
Schmid, M.1
Doberer, A.I.2
Schewzow, D.3
Weisshaar, K.4
Heinze, S.5
Bilban, G.6
Moser, M.7
Wolzt, E.8
-
108
-
-
0037377144
-
Heme activates the heme oxygenase-1 gene in renal epithelial cells by stabilizing Nrf2
-
J. Alam, E. Killeen, P. Gong, R. Naquin, B. Hu, D. Stewart, J.R. Ingelfinger, and K.A. Nath Heme activates the heme oxygenase-1 gene in renal epithelial cells by stabilizing Nrf2 Am J Physiol Renal Physiol 284 2003 F743 F752
-
(2003)
Am J Physiol Renal Physiol
, vol.284
, pp. F743-F752
-
-
Alam, J.1
Killeen, E.2
Gong, P.3
Naquin, R.4
Hu, B.5
Stewart, D.6
Ingelfinger, J.R.7
Nath, K.A.8
-
109
-
-
80054954486
-
Heme induces heme oxygenase 1 via Nrf2: Role in the homeostatic macrophage response to intraplaque hemorrhage
-
J.J. Boyle, M. Johns, J. Lo, A. Chiodini, N. Ambrose, P.C. Evans, J.C. Mason, and D.O. Haskard Heme induces heme oxygenase 1 via Nrf2: role in the homeostatic macrophage response to intraplaque hemorrhage Arterioscler Thromb Vasc Biol 31 2011 2685 2691
-
(2011)
Arterioscler Thromb Vasc Biol
, vol.31
, pp. 2685-2691
-
-
Boyle, J.J.1
Johns, M.2
Lo, J.3
Chiodini, A.4
Ambrose, N.5
Evans, P.C.6
Mason, J.C.7
Haskard, D.O.8
-
111
-
-
18644378321
-
Hemoprotein Bach1 regulates enhancer availability of heme oxygenase-1 gene
-
J. Sun, H. Hoshino, K. Takaku, O. Nakajima, A. Muto, H. Suzuki, S. Tashiro, S. Takahashi, S. Shibahara, J. Alam, M.M. Taketo, M. Yamamoto, and K. Igarashi Hemoprotein Bach1 regulates enhancer availability of heme oxygenase-1 gene EMBO J 21 2002 5216 5224
-
(2002)
EMBO J
, vol.21
, pp. 5216-5224
-
-
Sun, J.1
Hoshino, H.2
Takaku, K.3
Nakajima, O.4
Muto, A.5
Suzuki, H.6
Tashiro, S.7
Takahashi, S.8
Shibahara, S.9
Alam, J.10
Taketo, M.M.11
Yamamoto, M.12
Igarashi, K.13
-
113
-
-
25444449505
-
Lipopolysaccharide-induced heme oxygenase-1 expression in human monocytic cells is mediated via Nrf2 and protein kinase C
-
S.A. Rushworth, X.L. Chen, N. Mackman, R.M. Ogborne, and M.A. O'Connell Lipopolysaccharide-induced heme oxygenase-1 expression in human monocytic cells is mediated via Nrf2 and protein kinase C J Immunol 175 2005 4408 4415
-
(2005)
J Immunol
, vol.175
, pp. 4408-4415
-
-
Rushworth, S.A.1
Chen, X.L.2
Mackman, N.3
Ogborne, R.M.4
O'Connell, M.A.5
-
114
-
-
33645945014
-
Heme oxygenase-1/carbon monoxide: From basic science to therapeutic applications
-
S.W. Ryter, J. Alam, and A.M. Choi Heme oxygenase-1/carbon monoxide: from basic science to therapeutic applications Physiol Rev 86 2006 583 650
-
(2006)
Physiol Rev
, vol.86
, pp. 583-650
-
-
Ryter, S.W.1
Alam, J.2
Choi, A.M.3
-
115
-
-
37849018402
-
Hemin upregulates Egr-1 expression in vascular smooth muscle cells via reactive oxygen species ERK-1/2-Elk-1 and NF-kappaB
-
R.N. Hasan, and A.I. Schafer Hemin upregulates Egr-1 expression in vascular smooth muscle cells via reactive oxygen species ERK-1/2-Elk-1 and NF-kappaB Circ Res 102 2008 42 50
-
(2008)
Circ Res
, vol.102
, pp. 42-50
-
-
Hasan, R.N.1
Schafer, A.I.2
-
116
-
-
84879952268
-
Heminmediated neuroglobin induction exerts neuroprotection following ischemic brain injury through PI3K/Akt signaling
-
B. Zhang, X. Ji, S. Zhang, H. Ren, M. Wang, C. Guo, and Y. Li Heminmediated neuroglobin induction exerts neuroprotection following ischemic brain injury through PI3K/Akt signaling Molecular medicine reports 8 2013 681 685
-
(2013)
Molecular Medicine Reports
, vol.8
, pp. 681-685
-
-
Zhang, B.1
Ji, X.2
Zhang, S.3
Ren, H.4
Wang, M.5
Guo, C.6
Li, Y.7
-
117
-
-
70350140219
-
Hemoglobin induces the expression of indoleamine 2,3-dioxygenase in dendritic cells through the activation of PI3K, PKC, and NF-kappaB and the generation of reactive oxygen species
-
N. Ogasawara, T. Oguro, T. Sakabe, M. Matsushima, O. Takikawa, K. Isobe, and F. Nagase Hemoglobin induces the expression of indoleamine 2,3-dioxygenase in dendritic cells through the activation of PI3K, PKC, and NF-kappaB and the generation of reactive oxygen species Journal of cellular biochemistry 108 2009 716 725
-
(2009)
Journal of Cellular Biochemistry
, vol.108
, pp. 716-725
-
-
Ogasawara, N.1
Oguro, T.2
Sakabe, T.3
Matsushima, M.4
Takikawa, O.5
Isobe, K.6
Nagase, F.7
-
118
-
-
84907083339
-
Heme oxygenase-1 dysregulates macrophage polarization and the immune response to Helicobacter pylori
-
A.P. Gobert, T. Verriere, M. Asim, D.P. Barry, M.B. Piazuelo, T. de Sablet, A.G. Delgado, L.E. Bravo, P. Correa, R.M. Peek Jr, R. Chaturvedi, and K.T. Wilson Heme oxygenase-1 dysregulates macrophage polarization and the immune response to Helicobacter pylori J Immunol 193 2014 3013 3022
-
(2014)
J Immunol
, vol.193
, pp. 3013-3022
-
-
Gobert, A.P.1
Verriere, T.2
Asim, M.3
Barry, D.P.4
Piazuelo, M.B.5
De Sablet, T.6
Delgado, A.G.7
Bravo, L.E.8
Correa, P.9
Peek, R.M.10
Chaturvedi, R.11
Wilson, K.T.12
-
119
-
-
34250706879
-
Nitric oxide stimulates heme oxygenase-1 gene transcription via the Nrf2/ARE complex to promote vascular smooth muscle cell survival
-
X.M. Liu, K.J. Peyton, D. Ensenat, H. Wang, M. Hannink, J. Alam, and W. Durante Nitric oxide stimulates heme oxygenase-1 gene transcription via the Nrf2/ARE complex to promote vascular smooth muscle cell survival Cardiovascular research 75 2007 381 389
-
(2007)
Cardiovascular Research
, vol.75
, pp. 381-389
-
-
Liu, X.M.1
Peyton, K.J.2
Ensenat, D.3
Wang, H.4
Hannink, M.5
Alam, J.6
Durante, W.7
-
120
-
-
70149094547
-
Nitric oxide activation of Keap1/Nrf2 signaling in human colon carcinoma cells
-
C.Q. Li, M.Y. Kim, L.C. Godoy, A. Thiantanawat, L.J. Trudel, and G.N. Wogan Nitric oxide activation of Keap1/Nrf2 signaling in human colon carcinoma cells Proc Natl Acad Sci U S A 106 2009 14547 14551
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 14547-14551
-
-
Li, C.Q.1
Kim, M.Y.2
Godoy, L.C.3
Thiantanawat, A.4
Trudel, L.J.5
Wogan, G.N.6
-
121
-
-
84860189098
-
Activation of mitochondrial biogenesis by heme oxygenase-1-mediated NF-E2-related factor-2 induction rescues mice from lethal Staphylococcus aureus sepsis
-
N.C. MacGarvey, H.B. Suliman, R.R. Bartz, P. Fu, C.M. Withers, K.E. Welty-Wolf, and C.A. Piantadosi Activation of mitochondrial biogenesis by heme oxygenase-1-mediated NF-E2-related factor-2 induction rescues mice from lethal Staphylococcus aureus sepsis American journal of respiratory and critical care medicine 185 2012 851 861
-
(2012)
American Journal of Respiratory and Critical Care Medicine
, vol.185
, pp. 851-861
-
-
MacGarvey, N.C.1
Suliman, H.B.2
Bartz, R.R.3
Fu, P.4
Withers, C.M.5
Welty-Wolf, K.E.6
Piantadosi, C.A.7
-
122
-
-
79955542142
-
Heme oxygenase-1 couples activation of mitochondrial biogenesis to anti-inflammatory cytokine expression
-
C.A. Piantadosi, C.M. Withers, R.R. Bartz, N.C. MacGarvey, P. Fu, T.E. Sweeney, K.E. Welty-Wolf, and H.B. Suliman Heme oxygenase-1 couples activation of mitochondrial biogenesis to anti-inflammatory cytokine expression The Journal of biological chemistry 286 2011 16374 16385
-
(2011)
The Journal of Biological Chemistry
, vol.286
, pp. 16374-16385
-
-
Piantadosi, C.A.1
Withers, C.M.2
Bartz, R.R.3
MacGarvey, N.C.4
Fu, P.5
Sweeney, T.E.6
Welty-Wolf, K.E.7
Suliman, H.B.8
-
123
-
-
43049168497
-
Heme oxygenase-1 is an anti-inflammatory host factor that promotes murine plasmodium liver infection
-
S. Epiphanio, S.A. Mikolajczak, L.A. Goncalves, A. Pamplona, S. Portugal, S. Albuquerque, M. Goldberg, S. Rebelo, D.G. Anderson, A. Akinc, H.P. Vornlocher, S.H. Kappe, M.P. Soares, and M.M. Mota Heme oxygenase-1 is an anti-inflammatory host factor that promotes murine plasmodium liver infection Cell Host Microbe 3 2008 331 338
-
(2008)
Cell Host Microbe
, vol.3
, pp. 331-338
-
-
Epiphanio, S.1
Mikolajczak, S.A.2
Goncalves, L.A.3
Pamplona, A.4
Portugal, S.5
Albuquerque, S.6
Goldberg, M.7
Rebelo, S.8
Anderson, D.G.9
Akinc, A.10
Vornlocher, H.P.11
Kappe, S.H.12
Soares, M.P.13
Mota, M.M.14
-
124
-
-
84879426573
-
Heme catabolism by heme oxygenase-1 confers host resistance to Mycobacterium infection
-
S. Silva-Gomes, R. Appelberg, R. Larsen, M.P. Soares, and M.S. Gomes Heme catabolism by heme oxygenase-1 confers host resistance to Mycobacterium infection Infection and immunity 81 2013 2536 2545
-
(2013)
Infection and Immunity
, vol.81
, pp. 2536-2545
-
-
Silva-Gomes, S.1
Appelberg, R.2
Larsen, R.3
Soares, M.P.4
Gomes, M.S.5
-
125
-
-
84868540827
-
Heme oxygenase-1 promotes granuloma development and protects against dissemination of mycobacteria
-
D. Regev, R. Surolia, S. Karki, J. Zolak, A. Montes-Worboys, O. Oliva, P. Guroji, V. Saini, A.J. Steyn, A. Agarwal, and V.B. Antony Heme oxygenase-1 promotes granuloma development and protects against dissemination of mycobacteria Laboratory investigation; a journal of technical methods and pathology 92 2012 1541 1552
-
(2012)
Laboratory Investigation; a Journal of Technical Methods and Pathology
, vol.92
, pp. 1541-1552
-
-
Regev, D.1
Surolia, R.2
Karki, S.3
Zolak, J.4
Montes-Worboys, A.5
Oliva, O.6
Guroji, P.7
Saini, V.8
Steyn, A.J.9
Agarwal, A.10
Antony, V.B.11
-
126
-
-
84925221854
-
Heme oxygenase-1 and carbon monoxide regulate intestinal homeostasis and mucosal immune responses to the enteric microbiota
-
J.C. Onyiah, S.Z. Sheikh, N. Maharshak, L.E. Otterbein, and S.E. Plevy Heme oxygenase-1 and carbon monoxide regulate intestinal homeostasis and mucosal immune responses to the enteric microbiota Gut microbes 5 2014 220 224
-
(2014)
Gut Microbes
, vol.5
, pp. 220-224
-
-
Onyiah, J.C.1
Sheikh, S.Z.2
Maharshak, N.3
Otterbein, L.E.4
Plevy, S.E.5
-
127
-
-
81455141899
-
Disruption of nitric oxide signaling by Helicobacter pylori results in enhanced inflammation by inhibition of heme oxygenase-1
-
A.P. Gobert, M. Asim, M.B. Piazuelo, T. Verriere, B.P. Scull, T. de Sablet, A. Glumac, N.D. Lewis, P. Correa, R.M. Peek Jr, R. Chaturvedi, and K.T. Wilson Disruption of nitric oxide signaling by Helicobacter pylori results in enhanced inflammation by inhibition of heme oxygenase-1 J Immunol 187 2011 5370 5379
-
(2011)
J Immunol
, vol.187
, pp. 5370-5379
-
-
Gobert, A.P.1
Asim, M.2
Piazuelo, M.B.3
Verriere, T.4
Scull, B.P.5
De Sablet, T.6
Glumac, A.7
Lewis, N.D.8
Correa, P.9
Peek, R.M.10
Chaturvedi, R.11
Wilson, K.T.12
-
128
-
-
33646579079
-
Carbon monoxide orchestrates a protective response through PPARgamma
-
M. Bilban, F.H. Bach, S.L. Otterbein, E. Ifedigbo, J. de Costa d'Avila, H. Esterbauer, B.Y. Chin, A. Usheva, S.C. Robson, O. Wagner, and L.E. Otterbein Carbon monoxide orchestrates a protective response through PPARgamma Immunity 24 2006 601 610
-
(2006)
Immunity
, vol.24
, pp. 601-610
-
-
Bilban, M.1
Bach, F.H.2
Otterbein, S.L.3
Ifedigbo, E.4
De Costa d'Avila, J.5
Esterbauer, H.6
Chin, B.Y.7
Usheva, A.8
Robson, S.C.9
Wagner, O.10
Otterbein, L.E.11
-
129
-
-
34247571886
-
Hypoxia-inducible factor 1alpha stabilization by carbon monoxide results in cytoprotective preconditioning
-
B.Y. Chin, G. Jiang, B. Wegiel, H.J. Wang, T. Macdonald, X.C. Zhang, D. Gallo, E. Cszimadia, F.H. Bach, P.J. Lee, and L.E. Otterbein Hypoxia-inducible factor 1alpha stabilization by carbon monoxide results in cytoprotective preconditioning Proc Natl Acad Sci U S A 104 2007 5109 5114
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 5109-5114
-
-
Chin, B.Y.1
Jiang, G.2
Wegiel, B.3
Wang, H.J.4
Macdonald, T.5
Zhang, X.C.6
Gallo, D.7
Cszimadia, E.8
Bach, F.H.9
Lee, P.J.10
Otterbein, L.E.11
-
130
-
-
80055033765
-
Carbon monoxide induced PPARgamma SUMOylation and UCP2 block inflammatory gene expression in macrophages
-
A. Haschemi, B.Y. Chin, M. Jeitler, H. Esterbauer, O. Wagner, M. Bilban, and L.E. Otterbein Carbon monoxide induced PPARgamma SUMOylation and UCP2 block inflammatory gene expression in macrophages PloS one 6 2011 e26376
-
(2011)
PloS One
, vol.6
, pp. e26376
-
-
Haschemi, A.1
Chin, B.Y.2
Jeitler, M.3
Esterbauer, H.4
Wagner, O.5
Bilban, M.6
Otterbein, L.E.7
-
132
-
-
77149179384
-
Heme oxygenase 1 protects against hepatic hypoxia and injury from hemorrhage via regulation of cellular respiration
-
R. Vallabhaneni, D.J. Kaczorowski, M.D. Yaakovian, J. Rao, and B.S. Zuckerbraun Heme oxygenase 1 protects against hepatic hypoxia and injury from hemorrhage via regulation of cellular respiration Shock 33 2010 274 281
-
(2010)
Shock
, vol.33
, pp. 274-281
-
-
Vallabhaneni, R.1
Kaczorowski, D.J.2
Yaakovian, M.D.3
Rao, J.4
Zuckerbraun, B.S.5
-
133
-
-
27744536929
-
Carbon monoxide increases macrophage bacterial clearance through Toll-like receptor (TLR)4 expression
-
L.E. Otterbein, A. May, and B.Y. Chin Carbon monoxide increases macrophage bacterial clearance through Toll-like receptor (TLR)4 expression Cell Mol Biol (Noisy-le-grand) 51 2005 433 440
-
(2005)
Cell Mol Biol (Noisy-le-grand)
, vol.51
, pp. 433-440
-
-
Otterbein, L.E.1
May, A.2
Chin, B.Y.3
-
134
-
-
79251605391
-
Heme oxygenase-1/carbon monoxide: Novel therapeutic strategies in critical care medicine
-
S.W. Ryter, and A.M. Choi Heme oxygenase-1/carbon monoxide: novel therapeutic strategies in critical care medicine Current drug targets 11 2010 1485 1494
-
(2010)
Current Drug Targets
, vol.11
, pp. 1485-1494
-
-
Ryter, S.W.1
Choi, A.M.2
-
135
-
-
0034071424
-
Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway
-
L.E. Otterbein, F.H. Bach, J. Alam, M. Soares, Lu, H. Tao, M. Wysk, R.J. Davis, R.A. Flavell, and A.M. Choi Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway Nature medicine 6 2000 422 428
-
(2000)
Nature Medicine
, vol.6
, pp. 422-428
-
-
Otterbein, L.E.1
Bach, F.H.2
Alam, J.3
Soares, M.4
Tao, L.H.5
Wysk, M.6
Davis, R.J.7
Flavell, R.A.8
Choi, A.M.9
-
136
-
-
65649135789
-
Carbon monoxide rescues mice from lethal sepsis by supporting mitochondrial energetic metabolism and activating mitochondrial biogenesis
-
S. Lancel, S.M. Hassoun, R. Favory, B. Decoster, R. Motterlini, and R. Neviere Carbon monoxide rescues mice from lethal sepsis by supporting mitochondrial energetic metabolism and activating mitochondrial biogenesis J Pharmacol Exp Ther 329 2009 641 648
-
(2009)
J Pharmacol Exp Ther
, vol.329
, pp. 641-648
-
-
Lancel, S.1
Hassoun, S.M.2
Favory, R.3
Decoster, B.4
Motterlini, R.5
Neviere, R.6
-
137
-
-
84892592782
-
Carbon monoxide confers protection in sepsis by enhancing beclin 1-dependent autophagy and phagocytosis
-
S. Lee, S.J. Lee, A.A. Coronata, L.E. Fredenburgh, S.W. Chung, M.A. Perrella, K. Nakahira, S.W. Ryter, and A.M. Choi Carbon monoxide confers protection in sepsis by enhancing beclin 1-dependent autophagy and phagocytosis Antioxidants & redox signaling 20 2014 432 442
-
(2014)
Antioxidants & Redox Signaling
, vol.20
, pp. 432-442
-
-
Lee, S.1
Lee, S.J.2
Coronata, A.A.3
Fredenburgh, L.E.4
Chung, S.W.5
Perrella, M.A.6
Nakahira, K.7
Ryter, S.W.8
Choi, A.M.9
-
138
-
-
84896380454
-
Heme oxygenase-1: A metabolic nike
-
B. Wegiel, Z. Nemeth, M. Correa-Costa, A.C. Bulmer, and L.E. Otterbein Heme oxygenase-1: a metabolic nike Antioxidants & redox signaling 20 2014 1709 1722
-
(2014)
Antioxidants & Redox Signaling
, vol.20
, pp. 1709-1722
-
-
Wegiel, B.1
Nemeth, Z.2
Correa-Costa, M.3
Bulmer, A.C.4
Otterbein, L.E.5
-
139
-
-
65349103539
-
A carbon monoxide-releasing molecule (CORM-3) exerts bactericidal activity against Pseudomonas aeruginosa and improves survival in an animal model of bacteraemia
-
M. Desmard, K.S. Davidge, O. Bouvet, D. Morin, D. Roux, R. Foresti, J.D. Ricard, E. Denamur, R.K. Poole, P. Montravers, R. Motterlini, and J. Boczkowski A carbon monoxide-releasing molecule (CORM-3) exerts bactericidal activity against Pseudomonas aeruginosa and improves survival in an animal model of bacteraemia Faseb J 23 2009 1023 1031
-
(2009)
Faseb J
, vol.23
, pp. 1023-1031
-
-
Desmard, M.1
Davidge, K.S.2
Bouvet, O.3
Morin, D.4
Roux, D.5
Foresti, R.6
Ricard, J.D.7
Denamur, E.8
Poole, R.K.9
Montravers, P.10
Motterlini, R.11
Boczkowski, J.12
-
140
-
-
84898937448
-
Heme exporter FLVCR1a regulates heme synthesis and degradation and controls activity of cytochromes P450
-
F. Vinchi, G. Ingoglia, D. Chiabrando, S. Mercurio, E. Turco, L. Silengo, F. Altruda, and E. Tolosano Heme exporter FLVCR1a regulates heme synthesis and degradation and controls activity of cytochromes P450 Gastroenterology 146 2014 1325 1338
-
(2014)
Gastroenterology
, vol.146
, pp. 1325-1338
-
-
Vinchi, F.1
Ingoglia, G.2
Chiabrando, D.3
Mercurio, S.4
Turco, E.5
Silengo, L.6
Altruda, F.7
Tolosano, E.8
-
141
-
-
79952192382
-
Immune cell regulation by autocrine purinergic signalling
-
W.G. Junger Immune cell regulation by autocrine purinergic signalling Nature reviews. Immunology 11 2011 201 212
-
(2011)
Nature Reviews. Immunology
, vol.11
, pp. 201-212
-
-
Junger, W.G.1
-
143
-
-
84884854704
-
Systemic inflammatory responses and lung injury following hip fracture surgery increases susceptibility to infection in aged rats
-
H. Zhang, T. Sun, Z. Liu, J. Zhang, X. Wang, and J. Liu Systemic inflammatory responses and lung injury following hip fracture surgery increases susceptibility to infection in aged rats Mediators of inflammation 2013 2013 536435
-
(2013)
Mediators of Inflammation
, vol.2013
, pp. 536435
-
-
Zhang, H.1
Sun, T.2
Liu, Z.3
Zhang, J.4
Wang, X.5
Liu, J.6
-
144
-
-
84890852401
-
Release of extracellular ATP by bacteria during growth
-
R. Mempin, H. Tran, C. Chen, H. Gong, Ho, K. Kim, and S. Lu Release of extracellular ATP by bacteria during growth BMC microbiology 13 2013 301
-
(2013)
BMC Microbiology
, vol.13
, pp. 301
-
-
Mempin, R.1
Tran, H.2
Chen, C.3
Gong, H.4
Kim, H.K.5
Lu, S.6
-
145
-
-
84878077028
-
Adenosine-5'-triphosphate (ATP) protects mice against bacterial infection by activation of the NLRP3 inflammasome
-
Y. Xiang, X. Wang, C. Yan, Q. Gao, S.A. Li, J. Liu, K. Zhou, X. Guo, W. Lee, and Y. Zhang Adenosine-5'-triphosphate (ATP) protects mice against bacterial infection by activation of the NLRP3 inflammasome PloS one 8 2013 e63759
-
(2013)
PloS One
, vol.8
, pp. e63759
-
-
Xiang, Y.1
Wang, X.2
Yan, C.3
Gao, Q.4
Li, S.A.5
Liu, J.6
Zhou, K.7
Guo, X.8
Lee, W.9
Zhang, Y.10
-
146
-
-
34548226931
-
Heme induces neutrophil migration and reactive oxygen species generation through signaling pathways characteristic of chemotactic receptors
-
B.N. Porto, L.S. Alves, P.L. Fernandez, T.P. Dutra, R.T. Figueiredo, A.V. Graca-Souza, and M.T. Bozza Heme induces neutrophil migration and reactive oxygen species generation through signaling pathways characteristic of chemotactic receptors The Journal of biological chemistry 282 2007 24430 24436
-
(2007)
The Journal of Biological Chemistry
, vol.282
, pp. 24430-24436
-
-
Porto, B.N.1
Alves, L.S.2
Fernandez, P.L.3
Dutra, T.P.4
Figueiredo, R.T.5
Graca-Souza, A.V.6
Bozza, M.T.7
-
147
-
-
84907459327
-
Mitochondria regulate neutrophil activation by generating ATP for autocrine purinergic signaling
-
Y. Bao, C. Ledderose, T. Seier, A.F. Graf, B. Brix, E. Chong, and W.G. Junger Mitochondria regulate neutrophil activation by generating ATP for autocrine purinergic signaling The Journal of biological chemistry 289 2014 26794 26803
-
(2014)
The Journal of Biological Chemistry
, vol.289
, pp. 26794-26803
-
-
Bao, Y.1
Ledderose, C.2
Seier, T.3
Graf, A.F.4
Brix, B.5
Chong, E.6
Junger, W.G.7
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