Induction of ferritin and heme oxygenase-1 by endotoxin in the lung

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 275, Issue 3 19-3, 1998, Pages

  Carraway, M S ^a   Ghio, A J ^b   Taylor, J L ^a   Piantadosi, C A ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Acute lung injury; Lipopolysaccharide; Oxidants

Indexed keywords

FERRITIN; HEME OXYGENASE; LIPOPOLYSACCHARIDE;

ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; IRON TRANSPORT; LUNG INJURY; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TIME; TISSUE DISTRIBUTION;

EID: 0031714412     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.1998.275.3.l583     Document Type: Article

References (25)

1. Aziz, N., and H. N. Munro. Iron regulates ferritin mRNA translation through a segment of its 5′ untranslated region. Proc. Natl. Acad. Sci. USA 84: 8478-8482, 1987.
2. Balla, G., H. S. Jacob, J. Balla, M. Rosenberg, K. A. Nath, F. Apple, J. W. Eaton, and G. M. Vercellotti. Ferritin: a cytoprotective antioxidant strategy of endothelium. J. Biol. Chem. 267: 18148-18153, 1992.
3. Balla, J., H. S. Jacob, G. Balla, K. A. Nath, J. W. Eaton, and G. M. Vercellotti. Endothelial cell heme uptake from heme proteins: induction of sensitization and desensitization to oxidant damage. Proc. Natl. Acad. Sci. USA 90: 9285-9289, 1993.
4. Balla, J., K. A. Nath, G. Balla, M. B. Juckett, H. S. Jacob, and G. M. Vercellotti. Endothelial cell heme oxygenase and ferritin induction in rat lung by hemoglobin in vivo. Am. J. Physiol. 268 (Lung Cell. Mol. Physiol. 12): L321-L327, 1995.
5. Camhi, S. L., J. Alam, L. Otterbein, S. L. Sylvester, and A. M. K. Choi. Induction of heme oxygenase-1 gene expression by lipopolysaccharide is mediated by AP-1 activation. Am. J. Respir. Cell Mol. Biol. 13: 387-398, 1995.
6. Coughlin, R. T., S. Tonsager, and E. J. McGroarty. Quantitation of metal cations bound to membranes and extracted lipopolysaccharide of Escherichia coli. Biochemistry 22: 2002-2007, 1983.
7. Choi, A. M. K., and J. Alam. Heme oxygenase-1: function, regulation, and implication of a novel stress-inducible protein in oxidant-induced lung injury. Am. J. Respir. Cell Mol. Biol. 15: 9-19, 1996.
8. El-Shobaki, F., and W. Rummel. Mucosal iron binding proteins and the inhibition of iron absorption by endotoxin. Blut 50: 95-101, 1985.
9. Eisenstein, R. S., D. Garcia-Mayol, W. Pettingell, and H. N. Munro. Regulation of ferritin and heme oxygenase synthesis in rat fibroblasts by different forms of iron. Proc. Natl. Acad. Sci. USA 88: 688-692, 1991.
10. Fahmy, M., and S. P. Young. Modulation of iron metabolism in monocyte cell line U937 by inflammatory cytokines: changes in transferrin uptake, iron handling, and ferritin mRNA. Biochem. J. 926: 175-181, 1993.
11. Frevert, C. W., A. E. Warner, and L. Kobzik. Defective pulmonary recruitment of neutrophils in a rat model of endotoxemia. Am. J. Respir. Cell Mol. Biol. 11: 716-723, 1994.
12. Kumagai, M, A., and S. Okada. Mobilization of iron and iron-related proteins in rat spleen after intravenous injection of lipopolysaccharide (LPS). Pathol. Res. Pract. 188: 931-941, 1992.
13. Klausner, R. D., T. A. Rouault, and J. B. Harford. Regulating the fate of mRNA: the control of cellular iron metabolism. Cell 72: 19-28, 1993.
14. Lee, P. J., J. Alam, G. W. Weigand, and A. M. K. Choi. Overexpression of heme oxygenase-1 in human pulmonary epithelial cells results in cell growth arrest and increased resistance to hyperoxia. Proc. Natl. Acad. Sci. USA 93: 10393-10398, 1996.
15. Lowry, O. H., N. J. Rosebrough., A. L. Farr., and R. J. Randall. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193: 265-275, 1951.
16. Maines, M. D. Heme oxygenase: function, multiplicity, regulatory mechanisms, and clinical applications. FASEB J. 2: 2557-2568, 1988.
17. McCoubrey, W. K., Jr., T. J. Huang, and M. D. Maines. Isolation and characterization of a cDNA from the rat brain that encodes hemoprotein heme oxygenase-3. Eur. J. Biochem. 247: 725-732, 1997.
18. Nathens, A. B., R. Bitar, C. Davreux, M. Bujard, J. C. Marshall, A. P. B. Dackiw, R. W. G. Watson, and O. D. Rotstein. Pyrrolidine dithiocarbamate attenuates endotoxin-induced acute lung injury. Am. J. Respir. Cell Mol. Biol. 17: 608-616, 1997.
19. Otterbein, L., B. Y. Chin, S. L. Otterbein, V. C. Lowe, H. E. Fessier, and A. M. K. Choi. Mechanism of hemoglobin-induced protection against endotoxemia in rats: a ferritin-independent pathway. Am. J. Physiol. 272 (Lung Cell. Mol. Physiol. 16): L268-L275, 1997.
20. Otterbein, L., S. L. Sylvester, and A. M. K. Choi. Hemoglobin provides protection against lethal endotoxemia in rats: the role of heme oxygense-1. Am. J. Respir. Cell Mol. Biol. 13: 595-601, 1995.
21. Taylor, J., M. S. Carraway, and C. A. Piantadosi. Lung specific induction of heme oxygenase-1 and hyperoxic lung injury. Am. J. Physiol. 274 (Lung Cell. Mol. Physiol. 18): L582-L590, 1998.
22. Tenhunen, R., H. S. Marver, and R. Schmid. The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase. Proc. Natl. Acad. Sci. USA 61: 748-755, 1968.
23. Tenhunen, R., H. S. Marver, and R. Schmid. Microsomal heme oxygenase. J. Biol. Chem. 244: 6388-6394, 1969.
24. Vile, G. F., S. Basu-Modak, C. Waltner, and R. M. Tyrrell. Heme oxygenase-1 mediates an adaptive response to oxidative stress in human skin fibroblasts. Proc. Natl. Acad. Sci. USA 91: 2607-2610, 1994.
25. Vogt, B. A., A. J. Croatt, G. M. Vercellotti, and K. A. Nath. Acquired resistance to acute oxidative stress: possible role of heme oxygenase and ferritin. Lab. Invest. 72: 474-483, 1995.