Gene polymorphisms in the heme degradation pathway and outcome of severe human sepsis

Shock

Volumn 38, Issue 5, 2012, Pages 459-465

  Sponholz, Christoph ^a,b   Huse, Klaus ^b   Kramer, Marcel ^a,b   Giamarellos Bourboulis, Evangelos J ^c   Claus, Ralf A ^a   Kern, Anna ^a   Engel, Christoph ^d   Kuhnt, Evelyn ^d   Kiehntopf, Michael ^a   Routsi, Christina ^c   Mylona, Vassiliki ^e   Tsangaris, Iraklis ^c   Heinemann, Stefan H ^a   Reinhart, Konrad ^a   Platzer, Matthias ^b   Bauer, Michael ^a  

^a JENA UNIVERSITY HOSPITAL   (Germany)

^b FRITZ LIPMANN INSTITUTE   (Germany)

^c UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^d UNIVERSITY OF LEIPZIG   (Germany)

^e SISMANOGLIO HOSPITAL   (Greece)

Author keywords

biliverdin reductase; genotypes; Heme oxygenase; infection; mortality; organ failure

Indexed keywords

BILIVERDIN REDUCTASE A; BILIVERDIN REDUCTASE B; DNA; HEME OXYGENASE 1; OXIDOREDUCTASE; UNCLASSIFIED DRUG;

ADULT; AGED; ALLELE; ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; ENZYME BLOOD LEVEL; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC SCREENING; GENOTYPE; GENOTYPING TECHNIQUE; HOMOZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; MALE; MORTALITY; NUCLEOTIDE SEQUENCE; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SCORING SYSTEM; SEPSIS; SINGLE NUCLEOTIDE POLYMORPHISM; TREATMENT OUTCOME;

AGED; AGED, 80 AND OVER; COHORT STUDIES; FEMALE; HEME; HEME OXYGENASE-1; HUMANS; MALE; MICROSATELLITE REPEATS; MIDDLE AGED; OXIDOREDUCTASES ACTING ON CH-CH GROUP DONORS; POLYMORPHISM, SINGLE NUCLEOTIDE; SEPSIS; SEVERITY OF ILLNESS INDEX; SURVIVAL RATE;

EID: 84868198183     PISSN: 10732322     EISSN: 15400514     Source Type: Journal    
DOI: 10.1097/SHK.0b013e31826ae951     Document Type: Article

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