A carbon monoxide-releasing molecule (CORM-3) exerts bactericidal activity against Pseudomonas aeruginosa and improves survival in an animal model of bacteraemia

FASEB Journal

Volumn 23, Issue 4, 2009, Pages 1023-1031

  Desmard, Mathieu ^a,e   Davidge, Kelly S ^b   Bouvet, Odile ^a   Morin, Didier ^c   Roux, Damien ^a   Foresti, Roberta ^f,g   Ricard, Jean D ^a,d   Denamur, Erick ^a   Poole, Robert K ^b   Montravers, Philippe ^e   Motterlini, Roberto ^f,g   Boczkowski, Jorge ^a,e  

^a INSERM   (France)

^b UNIVERSITY OF SHEFFIELD   (United Kingdom)

^c FACULTÉ DE MÉDECINE   (France)

^d HÔPITAL LOUIS MOURIER   (France)

^e BICHAT HOSPITAL   (France)

^f NORTHWICK PARK INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^g ISTITUTO ITALIANO DI TECNOLOGIA   (Italy)

Author keywords

Anti infective agents; Microbiology; Pharmacology; Sepsis

Indexed keywords

ANTIINFECTIVE AGENT; CARBON MONOXIDE; CARBON MONOXIDE RELEASING MOLECULE; UNCLASSIFIED DRUG; ORGANOMETALLIC COMPOUND; TRICARBONYLCHLORO(GLYCINATO)RUTHENIUM(II);

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOTIC RESISTANCE; ARTICLE; BACTEREMIA; BACTERIAL COUNT; BACTERICIDAL ACTIVITY; BACTERIUM CARRIER; CELL SURVIVAL; CHEMICAL INTERACTION; COMPARATIVE STUDY; CONCENTRATION RESPONSE; CONTROLLED STUDY; EUKARYOTIC CELL; IMMUNOCOMPETENT CELL; IMMUNOMODULATION; IN VITRO STUDY; MALE; MOUSE; NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; RESPIRATORY CHAIN; SPLEEN; ANIMAL; CELL LINE; DOSE RESPONSE; DRUG EFFECT; GROWTH, DEVELOPMENT AND AGING; METHODOLOGY; TIME;

ANIMALIA; BACTERIA (MICROORGANISMS); EUKARYOTA; MUS; PSEUDOMONAS AERUGINOSA;

ANIMALS; ANTI-BACTERIAL AGENTS; BACTEREMIA; CELL LINE; CELL SURVIVAL; COLONY COUNT, MICROBIAL; DOSE-RESPONSE RELATIONSHIP, DRUG; MICE; MODELS, ANIMAL; ORGANOMETALLIC COMPOUNDS; OXYGEN CONSUMPTION; PSEUDOMONAS AERUGINOSA; TIME FACTORS;

EID: 65349103539     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.08-122804     Document Type: Article

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