-
1
-
-
52649167708
-
CD4 T cells: fates, functions, and faults
-
Zhu J., Paul W.E. CD4 T cells: fates, functions, and faults. Blood 2008, 112:1557-1569.
-
(2008)
Blood
, vol.112
, pp. 1557-1569
-
-
Zhu, J.1
Paul, W.E.2
-
2
-
-
77952313777
-
Differentiation of effector CD4 T cell populations
-
Zhu J., Yamane H., Paul W.E. Differentiation of effector CD4 T cell populations. Annu Rev Immunol 2010, 28:445-489.
-
(2010)
Annu Rev Immunol
, vol.28
, pp. 445-489
-
-
Zhu, J.1
Yamane, H.2
Paul, W.E.3
-
3
-
-
0022640843
-
Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins
-
Mosmann T.R., Cherwinski H., Bond M.W., Giedlin M.A., Coffman R.L. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J Immunol 1986, 136:2348-2357.
-
(1986)
J Immunol
, vol.136
, pp. 2348-2357
-
-
Mosmann, T.R.1
Cherwinski, H.2
Bond, M.W.3
Giedlin, M.A.4
Coffman, R.L.5
-
4
-
-
0024353079
-
TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties
-
Mosmann T.R., Coffman R.L. TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu Rev Immunol 1989, 7:145-173.
-
(1989)
Annu Rev Immunol
, vol.7
, pp. 145-173
-
-
Mosmann, T.R.1
Coffman, R.L.2
-
5
-
-
0028179006
-
Lymphocyte responses and cytokines
-
Paul W.E., Seder R.A. Lymphocyte responses and cytokines. Cell 1994, 76:241-251.
-
(1994)
Cell
, vol.76
, pp. 241-251
-
-
Paul, W.E.1
Seder, R.A.2
-
6
-
-
84859390119
-
Induced CD4+Foxp3+ regulatory T cells in immune tolerance
-
Bilate A.M., Lafaille J.J. Induced CD4+Foxp3+ regulatory T cells in immune tolerance. Annu Rev Immunol 2012, 30:733-758.
-
(2012)
Annu Rev Immunol
, vol.30
, pp. 733-758
-
-
Bilate, A.M.1
Lafaille, J.J.2
-
7
-
-
84875427488
-
Regulatory T cells: recommendations to simplify the nomenclature
-
Abbas A.K., et al. Regulatory T cells: recommendations to simplify the nomenclature. Nat Immunol 2013, 14:307-308.
-
(2013)
Nat Immunol
, vol.14
, pp. 307-308
-
-
Abbas, A.K.1
-
8
-
-
61949463911
-
IL-17 and Th17 Cells
-
Korn T., Bettelli E., Oukka M., Kuchroo V.K. IL-17 and Th17 Cells. Annu Rev Immunol 2009, 27:485-517.
-
(2009)
Annu Rev Immunol
, vol.27
, pp. 485-517
-
-
Korn, T.1
Bettelli, E.2
Oukka, M.3
Kuchroo, V.K.4
-
9
-
-
79952675131
-
Follicular helper CD4 T cells (TFH)
-
Crotty S. Follicular helper CD4 T cells (TFH). Annu Rev Immunol 2011, 29:621-663.
-
(2011)
Annu Rev Immunol
, vol.29
, pp. 621-663
-
-
Crotty, S.1
-
10
-
-
0027452977
-
Disruption of the murine IL-4 gene blocks Th2 cytokine responses
-
Kopf M., et al. Disruption of the murine IL-4 gene blocks Th2 cytokine responses. Nature 1993, 362:245-248.
-
(1993)
Nature
, vol.362
, pp. 245-248
-
-
Kopf, M.1
-
11
-
-
0037265240
-
Alternative activation of macrophages
-
Gordon S. Alternative activation of macrophages. Nat Rev Immunol 2003, 3:23-35.
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 23-35
-
-
Gordon, S.1
-
12
-
-
0024410891
-
Antibody to interleukin-5 inhibits helminth-induced eosinophilia in mice
-
Coffman R.L., Seymour B.W., Hudak S., Jackson J., Rennick D. Antibody to interleukin-5 inhibits helminth-induced eosinophilia in mice. Science (New York, NY) 1989, 245:308-310.
-
(1989)
Science (New York, NY)
, vol.245
, pp. 308-310
-
-
Coffman, R.L.1
Seymour, B.W.2
Hudak, S.3
Jackson, J.4
Rennick, D.5
-
13
-
-
0036344597
-
Direct effects of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma
-
Kuperman D.A., et al. Direct effects of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma. Nat Med 2002, 8:885-889.
-
(2002)
Nat Med
, vol.8
, pp. 885-889
-
-
Kuperman, D.A.1
-
14
-
-
0037775352
-
IL-13 effector functions
-
Wynn T.A. IL-13 effector functions. Annu Rev Immunol 2003, 21:425-456.
-
(2003)
Annu Rev Immunol
, vol.21
, pp. 425-456
-
-
Wynn, T.A.1
-
15
-
-
0032007351
-
IL-13, IL-4Ralpha, and Stat6 are required for the expulsion of the gastrointestinal nematode parasite Nippostrongylus brasiliensis
-
Urban J.F., et al. IL-13, IL-4Ralpha, and Stat6 are required for the expulsion of the gastrointestinal nematode parasite Nippostrongylus brasiliensis. Immunity 1998, 8:255-264.
-
(1998)
Immunity
, vol.8
, pp. 255-264
-
-
Urban, J.F.1
-
16
-
-
8644220507
-
Molecular analysis of a locus control region in the T helper 2 cytokine gene cluster: a target for STAT6 but not GATA3
-
Lee D.U., Rao A. Molecular analysis of a locus control region in the T helper 2 cytokine gene cluster: a target for STAT6 but not GATA3. Proc Natl Acad Sci USA 2004, 101:16010-16015.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 16010-16015
-
-
Lee, D.U.1
Rao, A.2
-
17
-
-
33646196946
-
Regulation of Th2 differentiation and Il4 locus accessibility
-
Ansel K.M., Djuretic I., Tanasa B., Rao A. Regulation of Th2 differentiation and Il4 locus accessibility. Annu Rev Immunol 2006, 24:607-656.
-
(2006)
Annu Rev Immunol
, vol.24
, pp. 607-656
-
-
Ansel, K.M.1
Djuretic, I.2
Tanasa, B.3
Rao, A.4
-
18
-
-
0025082313
-
Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells
-
Le Gros G., Ben-Sasson S.Z., Seder R., Finkelman F.D., Paul W.E. Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells. J Exp Med 1990, 172:921-929.
-
(1990)
J Exp Med
, vol.172
, pp. 921-929
-
-
Le Gros, G.1
Ben-Sasson, S.Z.2
Seder, R.3
Finkelman, F.D.4
Paul, W.E.5
-
19
-
-
0025222698
-
IL-4 directs the development of Th2-like helper effectors
-
Swain S.L., Weinberg A.D., English M., Huston G. IL-4 directs the development of Th2-like helper effectors. J Immunol 1990, 145:3796-3806.
-
(1990)
J Immunol
, vol.145
, pp. 3796-3806
-
-
Swain, S.L.1
Weinberg, A.D.2
English, M.3
Huston, G.4
-
20
-
-
0029876629
-
Stat6 is required for mediating responses to IL-4 and for development of Th2 cells
-
Kaplan M.H., Schindler U., Smiley S.T., Grusby M.J. Stat6 is required for mediating responses to IL-4 and for development of Th2 cells. Immunity 1996, 4:313-319.
-
(1996)
Immunity
, vol.4
, pp. 313-319
-
-
Kaplan, M.H.1
Schindler, U.2
Smiley, S.T.3
Grusby, M.J.4
-
21
-
-
15844374279
-
Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene
-
Shimoda K., et al. Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene. Nature 1996, 380:630-633.
-
(1996)
Nature
, vol.380
, pp. 630-633
-
-
Shimoda, K.1
-
22
-
-
15844404509
-
Essential role of Stat6 in IL-4 signalling
-
Takeda K., et al. Essential role of Stat6 in IL-4 signalling. Nature 1996, 380:627-630.
-
(1996)
Nature
, vol.380
, pp. 627-630
-
-
Takeda, K.1
-
23
-
-
0034653932
-
Single cell analysis reveals that IL-4 receptor/Stat6 signaling is not required for the in vivo or in vitro development of CD4+ lymphocytes with a Th2 cytokine profile
-
Jankovic D., et al. Single cell analysis reveals that IL-4 receptor/Stat6 signaling is not required for the in vivo or in vitro development of CD4+ lymphocytes with a Th2 cytokine profile. J Immunol 2000, 164:3047-3055.
-
(2000)
J Immunol
, vol.164
, pp. 3047-3055
-
-
Jankovic, D.1
-
24
-
-
0034162535
-
Stat6 regulation of in vivo IL-4 responses
-
Finkelman F.D., et al. Stat6 regulation of in vivo IL-4 responses. J Immunol 2000, 164:2303-2310.
-
(2000)
J Immunol
, vol.164
, pp. 2303-2310
-
-
Finkelman, F.D.1
-
25
-
-
4344647601
-
Basophils produce IL-4 and accumulate in tissues after infection with a Th2-inducing parasite
-
Min B., et al. Basophils produce IL-4 and accumulate in tissues after infection with a Th2-inducing parasite. J Exp Med 2004, 200:507-517.
-
(2004)
J Exp Med
, vol.200
, pp. 507-517
-
-
Min, B.1
-
26
-
-
1642362240
-
Type 2 immunity reflects orchestrated recruitment of cells committed to IL-4 production
-
Voehringer D., Shinkai K., Locksley R.M. Type 2 immunity reflects orchestrated recruitment of cells committed to IL-4 production. Immunity 2004, 20:267-277.
-
(2004)
Immunity
, vol.20
, pp. 267-277
-
-
Voehringer, D.1
Shinkai, K.2
Locksley, R.M.3
-
27
-
-
50449101434
-
In vivo studies fail to reveal a role for IL-4 or STAT6 signaling in Th2 lymphocyte differentiation
-
van Panhuys N., et al. In vivo studies fail to reveal a role for IL-4 or STAT6 signaling in Th2 lymphocyte differentiation. Proc Natl Acad Sci USA 2008, 105:12423-12428.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 12423-12428
-
-
van Panhuys, N.1
-
28
-
-
0030810155
-
The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells
-
Zheng W., Flavell R.A. The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells. Cell 1997, 89:587-596.
-
(1997)
Cell
, vol.89
, pp. 587-596
-
-
Zheng, W.1
Flavell, R.A.2
-
29
-
-
0030764961
-
Transcription factor GATA-3 is differentially expressed in murine Th1 and Th2 cells and controls Th2-specific expression of the interleukin-5 gene
-
Zhang D.H., Cohn L., Ray P., Bottomly K., Ray A. Transcription factor GATA-3 is differentially expressed in murine Th1 and Th2 cells and controls Th2-specific expression of the interleukin-5 gene. J Biol Chem 1997, 272:21597-21603.
-
(1997)
J Biol Chem
, vol.272
, pp. 21597-21603
-
-
Zhang, D.H.1
Cohn, L.2
Ray, P.3
Bottomly, K.4
Ray, A.5
-
30
-
-
9244263631
-
Conditional deletion of Gata3 shows its essential function in T(H)1-T(H)2 responses
-
Zhu J., et al. Conditional deletion of Gata3 shows its essential function in T(H)1-T(H)2 responses. Nat Immunol 2004, 5:1157-1165.
-
(2004)
Nat Immunol
, vol.5
, pp. 1157-1165
-
-
Zhu, J.1
-
31
-
-
1242274405
-
GATA-3 deficiency abrogates the development and maintenance of T helper type 2 cells
-
Pai S.Y., Truitt M.L., Ho I.C. GATA-3 deficiency abrogates the development and maintenance of T helper type 2 cells. Proc Natl Acad Sci USA 2004, 101:1993-1998.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 1993-1998
-
-
Pai, S.Y.1
Truitt, M.L.2
Ho, I.C.3
-
32
-
-
1642398043
-
Interleukin 2 plays a central role in Th2 differentiation
-
Cote-Sierra J., et al. Interleukin 2 plays a central role in Th2 differentiation. Proc Natl Acad Sci USA 2004, 101:3880-3885.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 3880-3885
-
-
Cote-Sierra, J.1
-
33
-
-
0344064893
-
Stat5 activation plays a critical role in Th2 differentiation
-
Zhu J., Cote-Sierra J., Guo L., Paul W.E. Stat5 activation plays a critical role in Th2 differentiation. Immunity 2003, 19:739-748.
-
(2003)
Immunity
, vol.19
, pp. 739-748
-
-
Zhu, J.1
Cote-Sierra, J.2
Guo, L.3
Paul, W.E.4
-
35
-
-
84885572626
-
Type 2 innate lymphoid cells control eosinophil homeostasis
-
Nussbaum J.C., et al. Type 2 innate lymphoid cells control eosinophil homeostasis. Nature 2013, 502:245-248.
-
(2013)
Nature
, vol.502
, pp. 245-248
-
-
Nussbaum, J.C.1
-
36
-
-
79958042030
-
Genome-wide analysis reveals unique regulation of transcription of Th2-specific genes by GATA3
-
Horiuchi S., et al. Genome-wide analysis reveals unique regulation of transcription of Th2-specific genes by GATA3. J Immunol 2011, 186:6378-6389.
-
(2011)
J Immunol
, vol.186
, pp. 6378-6389
-
-
Horiuchi, S.1
-
37
-
-
84878261946
-
TH2, allergy and group 2 innate lymphoid cells
-
Licona-Limon P., Kim L.K., Palm N.W., Flavell R.A. TH2, allergy and group 2 innate lymphoid cells. Nat Immunol 2013, 14:536-542.
-
(2013)
Nat Immunol
, vol.14
, pp. 536-542
-
-
Licona-Limon, P.1
Kim, L.K.2
Palm, N.W.3
Flavell, R.A.4
-
38
-
-
84896396519
-
The transcription factor GATA3 is critical for the development of all IL-7Ralpha-expressing innate lymphoid cells
-
Yagi R., et al. The transcription factor GATA3 is critical for the development of all IL-7Ralpha-expressing innate lymphoid cells. Immunity 2014, 40:378-388.
-
(2014)
Immunity
, vol.40
, pp. 378-388
-
-
Yagi, R.1
-
39
-
-
33745036694
-
Type 2 immunity is controlled by IL-4/IL-13 expression in hematopoietic non-eosinophil cells of the innate immune system
-
Voehringer D., Reese T.A., Huang X., Shinkai K., Locksley R.M. Type 2 immunity is controlled by IL-4/IL-13 expression in hematopoietic non-eosinophil cells of the innate immune system. J Exp Med 2006, 203:1435-1446.
-
(2006)
J Exp Med
, vol.203
, pp. 1435-1446
-
-
Voehringer, D.1
Reese, T.A.2
Huang, X.3
Shinkai, K.4
Locksley, R.M.5
-
40
-
-
0033427612
-
Ectopic expression of activated Stat6 induces the expression of Th2-specific cytokines and transcription factors in developing Th1 cells
-
Kurata H., Lee H.J., O'Garra A., Arai N. Ectopic expression of activated Stat6 induces the expression of Th2-specific cytokines and transcription factors in developing Th1 cells. Immunity 1999, 11:677-688.
-
(1999)
Immunity
, vol.11
, pp. 677-688
-
-
Kurata, H.1
Lee, H.J.2
O'Garra, A.3
Arai, N.4
-
41
-
-
0035877106
-
Stat6 is necessary and sufficient for IL-4's role in Th2 differentiation and cell expansion
-
Zhu J., Guo L., Watson C.J., Hu-Li J., Paul W.E. Stat6 is necessary and sufficient for IL-4's role in Th2 differentiation and cell expansion. J Immunol 2001, 166:7276-7281.
-
(2001)
J Immunol
, vol.166
, pp. 7276-7281
-
-
Zhu, J.1
Guo, L.2
Watson, C.J.3
Hu-Li, J.4
Paul, W.E.5
-
42
-
-
0028177589
-
CD4pos, NK1.1pos T cells promptly produce interleukin 4 in response to in vivo challenge with anti-CD3
-
Yoshimoto T., Paul W.E. CD4pos, NK1.1pos T cells promptly produce interleukin 4 in response to in vivo challenge with anti-CD3. J Exp Med 1994, 179:1285-1295.
-
(1994)
J Exp Med
, vol.179
, pp. 1285-1295
-
-
Yoshimoto, T.1
Paul, W.E.2
-
43
-
-
39449133957
-
A mechanism for the initiation of allergen-induced T helper type 2 responses
-
Sokol C.L., Barton G.M., Farr A.G., Medzhitov R. A mechanism for the initiation of allergen-induced T helper type 2 responses. Nat Immunol 2008, 9:310-318.
-
(2008)
Nat Immunol
, vol.9
, pp. 310-318
-
-
Sokol, C.L.1
Barton, G.M.2
Farr, A.G.3
Medzhitov, R.4
-
44
-
-
67649216604
-
Basophils function as antigen-presenting cells for an allergen-induced T helper type 2 response
-
Sokol C.L., et al. Basophils function as antigen-presenting cells for an allergen-induced T helper type 2 response. Nat Immunol 2009, 10:713-720.
-
(2009)
Nat Immunol
, vol.10
, pp. 713-720
-
-
Sokol, C.L.1
-
45
-
-
25144476332
-
Independent roles for IL-2 and GATA-3 in stimulating naive CD4+ T cells to generate a Th2-inducing cytokine environment
-
Yamane H., Zhu J., Paul W.E. Independent roles for IL-2 and GATA-3 in stimulating naive CD4+ T cells to generate a Th2-inducing cytokine environment. J Exp Med 2005, 202:793-804.
-
(2005)
J Exp Med
, vol.202
, pp. 793-804
-
-
Yamane, H.1
Zhu, J.2
Paul, W.E.3
-
46
-
-
0036114371
-
IL-4 secreted from individual naive CD4+ T cells acts in an autocrine manner to induce Th2 differentiation
-
Noben-Trauth N., Hu-Li J., Paul W.E. IL-4 secreted from individual naive CD4+ T cells acts in an autocrine manner to induce Th2 differentiation. Eur J Immunol 2002, 32:1428-1433.
-
(2002)
Eur J Immunol
, vol.32
, pp. 1428-1433
-
-
Noben-Trauth, N.1
Hu-Li, J.2
Paul, W.E.3
-
47
-
-
83855163410
-
Divergent expression patterns of IL-4 and IL-13 define unique functions in allergic immunity
-
Liang H.E., et al. Divergent expression patterns of IL-4 and IL-13 define unique functions in allergic immunity. Nat Immunol 2012, 13:58-66.
-
(2012)
Nat Immunol
, vol.13
, pp. 58-66
-
-
Liang, H.E.1
-
48
-
-
0031573660
-
Strength of TCR signal determines the costimulatory requirements for Th1 and Th2 CD4+ T cell differentiation
-
Tao X., Constant S., Jorritsma P., Bottomly K. Strength of TCR signal determines the costimulatory requirements for Th1 and Th2 CD4+ T cell differentiation. J Immunol 1997, 159:5956-5963.
-
(1997)
J Immunol
, vol.159
, pp. 5956-5963
-
-
Tao, X.1
Constant, S.2
Jorritsma, P.3
Bottomly, K.4
-
49
-
-
84904443484
-
T-cell-receptor-dependent signal intensity dominantly controls CD4(+) T cell polarization In Vivo
-
van Panhuys N., Klauschen F., Germain R.N. T-cell-receptor-dependent signal intensity dominantly controls CD4(+) T cell polarization In Vivo. Immunity 2014, 41:63-74.
-
(2014)
Immunity
, vol.41
, pp. 63-74
-
-
van Panhuys, N.1
Klauschen, F.2
Germain, R.N.3
-
50
-
-
85017870176
-
T cell receptor cross-reactivity between similar foreign and self peptides influences naive cell population size and autoimmunity
-
Nelson R.W., et al. T cell receptor cross-reactivity between similar foreign and self peptides influences naive cell population size and autoimmunity. Immunity 2014.
-
(2014)
Immunity
-
-
Nelson, R.W.1
-
51
-
-
84877710866
-
Single naive CD4+ T cells from a diverse repertoire produce different effector cell types during infection
-
Tubo N.J., et al. Single naive CD4+ T cells from a diverse repertoire produce different effector cell types during infection. Cell 2013, 153:785-796.
-
(2013)
Cell
, vol.153
, pp. 785-796
-
-
Tubo, N.J.1
-
52
-
-
0034670044
-
Cyclic AMP activates p38 mitogen-activated protein kinase in Th2 cells: phosphorylation of GATA-3 and stimulation of Th2 cytokine gene expression
-
Chen C.H., Zhang D.H., LaPorte J.M., Ray A. Cyclic AMP activates p38 mitogen-activated protein kinase in Th2 cells: phosphorylation of GATA-3 and stimulation of Th2 cytokine gene expression. J Immunol 2000, 165:5597-5605.
-
(2000)
J Immunol
, vol.165
, pp. 5597-5605
-
-
Chen, C.H.1
Zhang, D.H.2
LaPorte, J.M.3
Ray, A.4
-
53
-
-
0031775744
-
Resting respiratory tract dendritic cells preferentially stimulate T helper cell type 2 (Th2) responses and require obligatory cytokine signals for induction of Th1 immunity
-
Stumbles P.A., et al. Resting respiratory tract dendritic cells preferentially stimulate T helper cell type 2 (Th2) responses and require obligatory cytokine signals for induction of Th1 immunity. J Exp Med 1998, 188:2019-2031.
-
(1998)
J Exp Med
, vol.188
, pp. 2019-2031
-
-
Stumbles, P.A.1
-
54
-
-
68149163162
-
The major component in schistosome eggs responsible for conditioning dendritic cells for Th2 polarization is a T2 ribonuclease (omega-1)
-
Steinfelder S., et al. The major component in schistosome eggs responsible for conditioning dendritic cells for Th2 polarization is a T2 ribonuclease (omega-1). J Exp Med 2009, 206:1681-1690.
-
(2009)
J Exp Med
, vol.206
, pp. 1681-1690
-
-
Steinfelder, S.1
-
55
-
-
68149156007
-
Omega-1, a glycoprotein secreted by Schistosoma mansoni eggs, drives Th2 responses
-
Everts B., et al. Omega-1, a glycoprotein secreted by Schistosoma mansoni eggs, drives Th2 responses. J Exp Med 2009, 206:1673-1680.
-
(2009)
J Exp Med
, vol.206
, pp. 1673-1680
-
-
Everts, B.1
-
56
-
-
67649227119
-
Basophils contribute to T(H)2-IgE responses in vivo via IL-4 production and presentation of peptide-MHC class II complexes to CD4+ T cells
-
Yoshimoto T., et al. Basophils contribute to T(H)2-IgE responses in vivo via IL-4 production and presentation of peptide-MHC class II complexes to CD4+ T cells. Nat Immunol 2009, 10:706-712.
-
(2009)
Nat Immunol
, vol.10
, pp. 706-712
-
-
Yoshimoto, T.1
-
57
-
-
67649229687
-
MHC class II-dependent basophil-CD4+ T cell interactions promote T(H)2 cytokine-dependent immunity
-
Perrigoue J.G., et al. MHC class II-dependent basophil-CD4+ T cell interactions promote T(H)2 cytokine-dependent immunity. Nat Immunol 2009, 10:697-705.
-
(2009)
Nat Immunol
, vol.10
, pp. 697-705
-
-
Perrigoue, J.G.1
-
58
-
-
0028123444
-
CD28-mediated costimulation of interleukin 2 (IL-2) production plays a critical role in T cell priming for IL-4 and interferon gamma production
-
Seder R.A., Germain R.N., Linsley P.S., Paul W.E. CD28-mediated costimulation of interleukin 2 (IL-2) production plays a critical role in T cell priming for IL-4 and interferon gamma production. J Exp Med 1994, 179:299-304.
-
(1994)
J Exp Med
, vol.179
, pp. 299-304
-
-
Seder, R.A.1
Germain, R.N.2
Linsley, P.S.3
Paul, W.E.4
-
59
-
-
16044371193
-
CD28/B7 regulation of Th1 and Th2 subsets in the development of autoimmune diabetes
-
Lenschow D.J., et al. CD28/B7 regulation of Th1 and Th2 subsets in the development of autoimmune diabetes. Immunity 1996, 5:285-293.
-
(1996)
Immunity
, vol.5
, pp. 285-293
-
-
Lenschow, D.J.1
-
60
-
-
0028089795
-
Differential effects of blockade of CD28-B7 on the development of Th1 or Th2 effector cells in experimental leishmaniasis
-
Corry D.B., Reiner S.L., Linsley P.S., Locksley R.M. Differential effects of blockade of CD28-B7 on the development of Th1 or Th2 effector cells in experimental leishmaniasis. J Immunol 1994, 153:4142-4148.
-
(1994)
J Immunol
, vol.153
, pp. 4142-4148
-
-
Corry, D.B.1
Reiner, S.L.2
Linsley, P.S.3
Locksley, R.M.4
-
61
-
-
0033198045
-
The role of CTLA-4 in regulating Th2 differentiation
-
Oosterwegel M.A., et al. The role of CTLA-4 in regulating Th2 differentiation. J Immunol 1999, 163:2634-2639.
-
(1999)
J Immunol
, vol.163
, pp. 2634-2639
-
-
Oosterwegel, M.A.1
-
62
-
-
0037320926
-
CTLA-4 regulates the requirement for cytokine-induced signals in T(H)2 lineage commitment
-
Bour-Jordan H., et al. CTLA-4 regulates the requirement for cytokine-induced signals in T(H)2 lineage commitment. Nat Immunol 2003, 4:182-188.
-
(2003)
Nat Immunol
, vol.4
, pp. 182-188
-
-
Bour-Jordan, H.1
-
63
-
-
0038433326
-
Transcriptional regulation of th2 differentiation by inducible costimulator
-
Nurieva R.I., et al. Transcriptional regulation of th2 differentiation by inducible costimulator. Immunity 2003, 18:801-811.
-
(2003)
Immunity
, vol.18
, pp. 801-811
-
-
Nurieva, R.I.1
-
64
-
-
13544277680
-
ICOS-mediated costimulation on Th2 differentiation is achieved by the enhancement of IL-4 receptor-mediated signaling
-
Watanabe M., et al. ICOS-mediated costimulation on Th2 differentiation is achieved by the enhancement of IL-4 receptor-mediated signaling. J Immunol 2005, 174:1989-1996.
-
(2005)
J Immunol
, vol.174
, pp. 1989-1996
-
-
Watanabe, M.1
-
65
-
-
0031872028
-
CD4 T cell cytokine differentiation: the B cell activation molecule, OX40 ligand, instructs CD4 T cells to express interleukin 4 and upregulates expression of the chemokine receptor, Blr-1
-
Flynn S., Toellner K.M., Raykundalia C., Goodall M., Lane P. CD4 T cell cytokine differentiation: the B cell activation molecule, OX40 ligand, instructs CD4 T cells to express interleukin 4 and upregulates expression of the chemokine receptor, Blr-1. J Exp Med 1998, 188:297-304.
-
(1998)
J Exp Med
, vol.188
, pp. 297-304
-
-
Flynn, S.1
Toellner, K.M.2
Raykundalia, C.3
Goodall, M.4
Lane, P.5
-
66
-
-
0032213337
-
OX40 costimulation enhances interleukin-4 (IL-4) expression at priming and promotes the differentiation of naive human CD4(+) T cells into high IL-4-producing effectors
-
Ohshima Y., et al. OX40 costimulation enhances interleukin-4 (IL-4) expression at priming and promotes the differentiation of naive human CD4(+) T cells into high IL-4-producing effectors. Blood 1998, 92:3338-3345.
-
(1998)
Blood
, vol.92
, pp. 3338-3345
-
-
Ohshima, Y.1
-
67
-
-
27744510433
-
TSLP-activated dendritic cells induce an inflammatory T helper type 2 cell response through OX40 ligand
-
Ito T., et al. TSLP-activated dendritic cells induce an inflammatory T helper type 2 cell response through OX40 ligand. J Exp Med 2005, 202:1213-1223.
-
(2005)
J Exp Med
, vol.202
, pp. 1213-1223
-
-
Ito, T.1
-
68
-
-
84919872308
-
Regulation of T cells by mTOR: the known knowns and the known unknowns
-
Pollizzi K.N., Powell J.D. Regulation of T cells by mTOR: the known knowns and the known unknowns. Trends Immunol 2015, 36:13-20.
-
(2015)
Trends Immunol
, vol.36
, pp. 13-20
-
-
Pollizzi, K.N.1
Powell, J.D.2
-
69
-
-
84860237060
-
Regulation and function of mTOR signalling in T cell fate decisions
-
Chi H. Regulation and function of mTOR signalling in T cell fate decisions. Nat Rev Immunol 2012, 12:325-338.
-
(2012)
Nat Rev Immunol
, vol.12
, pp. 325-338
-
-
Chi, H.1
-
70
-
-
0344196985
-
Regulation of IL-4 expression by the transcription factor JunB during T helper cell differentiation
-
Li B., Tournier C., Davis R.J., Flavell R.A. Regulation of IL-4 expression by the transcription factor JunB during T helper cell differentiation. EMBO J 1999, 18:420-432.
-
(1999)
EMBO J
, vol.18
, pp. 420-432
-
-
Li, B.1
Tournier, C.2
Davis, R.J.3
Flavell, R.A.4
-
71
-
-
77953897189
-
Mammalian target of rapamycin protein complex 2 regulates differentiation of Th1 and Th2 cell subsets via distinct signaling pathways
-
Lee K., et al. Mammalian target of rapamycin protein complex 2 regulates differentiation of Th1 and Th2 cell subsets via distinct signaling pathways. Immunity 2010, 32:743-753.
-
(2010)
Immunity
, vol.32
, pp. 743-753
-
-
Lee, K.1
-
72
-
-
79952985551
-
The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2
-
Delgoffe G.M., et al. The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2. Nat Immunol 2011, 12:295-303.
-
(2011)
Nat Immunol
, vol.12
, pp. 295-303
-
-
Delgoffe, G.M.1
-
73
-
-
84899094151
-
The AGC kinase SGK1 regulates TH1 and TH2 differentiation downstream of the mTORC2 complex
-
Heikamp E.B., et al. The AGC kinase SGK1 regulates TH1 and TH2 differentiation downstream of the mTORC2 complex. Nat Immunol 2014, 15:457-464.
-
(2014)
Nat Immunol
, vol.15
, pp. 457-464
-
-
Heikamp, E.B.1
-
74
-
-
84890137621
-
T cell exit from quiescence and differentiation into Th2 cells depend on Raptor-mTORC1-mediated metabolic reprogramming
-
Yang K., et al. T cell exit from quiescence and differentiation into Th2 cells depend on Raptor-mTORC1-mediated metabolic reprogramming. Immunity 2013, 39:1043-1056.
-
(2013)
Immunity
, vol.39
, pp. 1043-1056
-
-
Yang, K.1
-
75
-
-
78649881442
-
TCR-dependent translational control of GATA-3 enhances Th2 differentiation
-
Cook K.D., Miller J. TCR-dependent translational control of GATA-3 enhances Th2 differentiation. J Immunol 2010, 185:3209-3216.
-
(2010)
J Immunol
, vol.185
, pp. 3209-3216
-
-
Cook, K.D.1
Miller, J.2
-
76
-
-
2342496710
-
Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells
-
Amsen D., et al. Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells. Cell 2004, 117:515-526.
-
(2004)
Cell
, vol.117
, pp. 515-526
-
-
Amsen, D.1
-
77
-
-
2442522357
-
Regulation of alphabeta/gammadelta T cell lineage commitment and peripheral T cell responses by Notch/RBP-J signaling
-
Tanigaki K., et al. Regulation of alphabeta/gammadelta T cell lineage commitment and peripheral T cell responses by Notch/RBP-J signaling. Immunity 2004, 20:611-622.
-
(2004)
Immunity
, vol.20
, pp. 611-622
-
-
Tanigaki, K.1
-
78
-
-
34447634411
-
Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch
-
Amsen D., et al. Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch. Immunity 2007, 27:89-99.
-
(2007)
Immunity
, vol.27
, pp. 89-99
-
-
Amsen, D.1
-
79
-
-
84921315205
-
Notch signaling regulates antigen sensitivity of naive CD4(+) T cells by tuning co-stimulation
-
Laky K., Evans S., Perez-Diez A., Fowlkes B.J. Notch signaling regulates antigen sensitivity of naive CD4(+) T cells by tuning co-stimulation. Immunity 2015, 42:80-94.
-
(2015)
Immunity
, vol.42
, pp. 80-94
-
-
Laky, K.1
Evans, S.2
Perez-Diez, A.3
Fowlkes, B.J.4
-
80
-
-
0042834334
-
Notch signaling augments T cell responsiveness by enhancing CD25 expression
-
Adler S.H., et al. Notch signaling augments T cell responsiveness by enhancing CD25 expression. J Immunol 2003, 171:2896-2903.
-
(2003)
J Immunol
, vol.171
, pp. 2896-2903
-
-
Adler, S.H.1
-
81
-
-
0034657396
-
The role of Stat5a and Stat5b in signaling by IL-2 family cytokines
-
Lin J.X., Leonard W.J. The role of Stat5a and Stat5b in signaling by IL-2 family cytokines. Oncogene 2000, 19:2566-2576.
-
(2000)
Oncogene
, vol.19
, pp. 2566-2576
-
-
Lin, J.X.1
Leonard, W.J.2
-
82
-
-
0033082138
-
Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells
-
Moriggl R., et al. Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells. Immunity 1999, 10:249-259.
-
(1999)
Immunity
, vol.10
, pp. 249-259
-
-
Moriggl, R.1
-
83
-
-
0035871883
-
Stat5a regulates T helper cell differentiation by several distinct mechanisms
-
Kagami S., et al. Stat5a regulates T helper cell differentiation by several distinct mechanisms. Blood 2001, 97:2358-2365.
-
(2001)
Blood
, vol.97
, pp. 2358-2365
-
-
Kagami, S.1
-
84
-
-
0034651636
-
Both stat5a and stat5b are required for antigen-induced eosinophil and T-cell recruitment into the tissue
-
Kagami S., et al. Both stat5a and stat5b are required for antigen-induced eosinophil and T-cell recruitment into the tissue. Blood 2000, 95:1370-1377.
-
(2000)
Blood
, vol.95
, pp. 1370-1377
-
-
Kagami, S.1
-
85
-
-
25844515028
-
Thymic stromal lymphopoietin as a key initiator of allergic airway inflammation in mice
-
Zhou B., et al. Thymic stromal lymphopoietin as a key initiator of allergic airway inflammation in mice. Nat Immunol 2005, 6:1047-1053.
-
(2005)
Nat Immunol
, vol.6
, pp. 1047-1053
-
-
Zhou, B.1
-
86
-
-
33344455022
-
Thymic stromal lymphopoietin: master switch for allergic inflammation
-
Liu Y.J. Thymic stromal lymphopoietin: master switch for allergic inflammation. J Exp Med 2006, 203:269-273.
-
(2006)
J Exp Med
, vol.203
, pp. 269-273
-
-
Liu, Y.J.1
-
87
-
-
34247891512
-
TSLP: an epithelial cell cytokine that regulates T cell differentiation by conditioning dendritic cell maturation
-
Liu Y.J., et al. TSLP: an epithelial cell cytokine that regulates T cell differentiation by conditioning dendritic cell maturation. Annu Rev Immunol 2007, 25:193-219.
-
(2007)
Annu Rev Immunol
, vol.25
, pp. 193-219
-
-
Liu, Y.J.1
-
88
-
-
50149084878
-
TSLP acts on infiltrating effector T cells to drive allergic skin inflammation
-
He R., et al. TSLP acts on infiltrating effector T cells to drive allergic skin inflammation. Proc Natl Acad Sci USA 2008, 105:11875-11880.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 11875-11880
-
-
He, R.1
-
89
-
-
33846515975
-
Induction of IL-4 expression in CD4(+) T cells by thymic stromal lymphopoietin
-
Omori M., Ziegler S. Induction of IL-4 expression in CD4(+) T cells by thymic stromal lymphopoietin. J Immunol 2007, 178:1396-1404.
-
(2007)
J Immunol
, vol.178
, pp. 1396-1404
-
-
Omori, M.1
Ziegler, S.2
-
90
-
-
0034675851
-
Transient inhibition of interleukin 4 signaling by T cell receptor ligation
-
Zhu J., et al. Transient inhibition of interleukin 4 signaling by T cell receptor ligation. J Exp Med 2000, 192:1125-1134.
-
(2000)
J Exp Med
, vol.192
, pp. 1125-1134
-
-
Zhu, J.1
-
91
-
-
0035997908
-
T-bet is a STAT1-induced regulator of IL-12R expression in naive CD4+ T cells
-
Afkarian M., et al. T-bet is a STAT1-induced regulator of IL-12R expression in naive CD4+ T cells. Nat Immunol 2002, 3:549-557.
-
(2002)
Nat Immunol
, vol.3
, pp. 549-557
-
-
Afkarian, M.1
-
92
-
-
0035910037
-
T-bet is rapidly induced by interferon-gamma in lymphoid and myeloid cells
-
Lighvani A.A., et al. T-bet is rapidly induced by interferon-gamma in lymphoid and myeloid cells. Proc Natl Acad Sci USA 2001, 98:15137-15142.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 15137-15142
-
-
Lighvani, A.A.1
-
93
-
-
13444262764
-
Induced recruitment of NK cells to lymph nodes provides IFN-gamma for T(H)1 priming
-
Martin-Fontecha A., et al. Induced recruitment of NK cells to lymph nodes provides IFN-gamma for T(H)1 priming. Nat Immunol 2004, 5:1260-1265.
-
(2004)
Nat Immunol
, vol.5
, pp. 1260-1265
-
-
Martin-Fontecha, A.1
-
94
-
-
20644472421
-
Transforming growth factor-beta controls T helper type 1 cell development through regulation of natural killer cell interferon-gamma
-
Laouar Y., Sutterwala F.S., Gorelik L., Flavell R.A. Transforming growth factor-beta controls T helper type 1 cell development through regulation of natural killer cell interferon-gamma. Nat Immunol 2005, 6:600-607.
-
(2005)
Nat Immunol
, vol.6
, pp. 600-607
-
-
Laouar, Y.1
Sutterwala, F.S.2
Gorelik, L.3
Flavell, R.A.4
-
95
-
-
84863007648
-
NK cell-derived interferon-gamma orchestrates cellular dynamics and the differentiation of monocytes into dendritic cells at the site of infection
-
Goldszmid R.S., et al. NK cell-derived interferon-gamma orchestrates cellular dynamics and the differentiation of monocytes into dendritic cells at the site of infection. Immunity 2012, 36:1047-1059.
-
(2012)
Immunity
, vol.36
, pp. 1047-1059
-
-
Goldszmid, R.S.1
-
96
-
-
84898640432
-
Differentiation of type 1 ILCs from a common progenitor to all helper-like innate lymphoid cell lineages
-
Klose C.S., et al. Differentiation of type 1 ILCs from a common progenitor to all helper-like innate lymphoid cell lineages. Cell 2014, 157:340-356.
-
(2014)
Cell
, vol.157
, pp. 340-356
-
-
Klose, C.S.1
-
97
-
-
0029937270
-
Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice
-
Kaplan M.H., Sun Y.L., Hoey T., Grusby M.J. Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice. Nature 1996, 382:174-177.
-
(1996)
Nature
, vol.382
, pp. 174-177
-
-
Kaplan, M.H.1
Sun, Y.L.2
Hoey, T.3
Grusby, M.J.4
-
98
-
-
15844396183
-
Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells
-
Thierfelder W.E., et al. Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells. Nature 1996, 382:171-174.
-
(1996)
Nature
, vol.382
, pp. 171-174
-
-
Thierfelder, W.E.1
-
99
-
-
0027336689
-
Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages
-
Hsieh C.S., et al. Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages. Science (New York, NY) 1993, 260:547-549.
-
(1993)
Science (New York, NY)
, vol.260
, pp. 547-549
-
-
Hsieh, C.S.1
-
100
-
-
58849104422
-
GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation
-
Ho I.C., Tai T.S., Pai S.Y. GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol 2009, 9:125-135.
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 125-135
-
-
Ho, I.C.1
Tai, T.S.2
Pai, S.Y.3
-
101
-
-
80051885764
-
Genome-wide analyses of transcription factor GATA3-mediated gene regulation in distinct T cell types
-
Wei G., et al. Genome-wide analyses of transcription factor GATA3-mediated gene regulation in distinct T cell types. Immunity 2011, 35:299-311.
-
(2011)
Immunity
, vol.35
, pp. 299-311
-
-
Wei, G.1
-
102
-
-
0028006251
-
Cytokine-mediated regulation of chronic intestinal helminth infection
-
Else K.J., Finkelman F.D., Maliszewski C.R., Grencis R.K. Cytokine-mediated regulation of chronic intestinal helminth infection. J Exp Med 1994, 179:347-351.
-
(1994)
J Exp Med
, vol.179
, pp. 347-351
-
-
Else, K.J.1
Finkelman, F.D.2
Maliszewski, C.R.3
Grencis, R.K.4
-
103
-
-
0034677646
-
A novel transcription factor, T-bet, directs Th1 lineage commitment
-
Szabo S.J., et al. A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell 2000, 100:655-669.
-
(2000)
Cell
, vol.100
, pp. 655-669
-
-
Szabo, S.J.1
-
104
-
-
84867827632
-
The transcription factor T-bet is induced by multiple pathways and prevents an endogenous Th2 cell program during Th1 cell responses
-
Zhu J., et al. The transcription factor T-bet is induced by multiple pathways and prevents an endogenous Th2 cell program during Th1 cell responses. Immunity 2012, 37:660-673.
-
(2012)
Immunity
, vol.37
, pp. 660-673
-
-
Zhu, J.1
-
105
-
-
0036199625
-
In the absence of IL-12, CD4(+) T cell responses to intracellular pathogens fail to default to a Th2 pattern and are host protective in an IL-10(-/-) setting
-
Jankovic D., et al. In the absence of IL-12, CD4(+) T cell responses to intracellular pathogens fail to default to a Th2 pattern and are host protective in an IL-10(-/-) setting. Immunity 2002, 16:429-439.
-
(2002)
Immunity
, vol.16
, pp. 429-439
-
-
Jankovic, D.1
-
106
-
-
0032212793
-
Inhibition of Th1 development mediated by GATA-3 through an IL-4-independent mechanism
-
Ouyang W., et al. Inhibition of Th1 development mediated by GATA-3 through an IL-4-independent mechanism. Immunity 1998, 9:745-755.
-
(1998)
Immunity
, vol.9
, pp. 745-755
-
-
Ouyang, W.1
-
107
-
-
33645065358
-
T-bet regulates Th1 responses through essential effects on GATA-3 function rather than on IFNG gene acetylation and transcription
-
Usui T., et al. T-bet regulates Th1 responses through essential effects on GATA-3 function rather than on IFNG gene acetylation and transcription. J Exp Med 2006, 203:755-766.
-
(2006)
J Exp Med
, vol.203
, pp. 755-766
-
-
Usui, T.1
-
108
-
-
0033973582
-
Stat6-independent GATA-3 autoactivation directs IL-4-independent Th2 development and commitment
-
Ouyang W., et al. Stat6-independent GATA-3 autoactivation directs IL-4-independent Th2 development and commitment. Immunity 2000, 12:27-37.
-
(2000)
Immunity
, vol.12
, pp. 27-37
-
-
Ouyang, W.1
-
109
-
-
0033212806
-
Inhibition of allergic inflammation in a murine model of asthma by expression of a dominant-negative mutant of GATA-3
-
Zhang D.H., et al. Inhibition of allergic inflammation in a murine model of asthma by expression of a dominant-negative mutant of GATA-3. Immunity 1999, 11:473-482.
-
(1999)
Immunity
, vol.11
, pp. 473-482
-
-
Zhang, D.H.1
-
110
-
-
79960035010
-
An updated view on transcription factor GATA3-mediated regulation of Th1 and Th2 cell differentiation
-
Yagi R., Zhu J., Paul W.E. An updated view on transcription factor GATA3-mediated regulation of Th1 and Th2 cell differentiation. Int Immunol 2011, 23:415-420.
-
(2011)
Int Immunol
, vol.23
, pp. 415-420
-
-
Yagi, R.1
Zhu, J.2
Paul, W.E.3
-
111
-
-
0036830465
-
Identification of a conserved GATA3 response element upstream proximal from the interleukin-13 gene locus
-
Yamashita M., et al. Identification of a conserved GATA3 response element upstream proximal from the interleukin-13 gene locus. J Biol Chem 2002, 277:42399-42408.
-
(2002)
J Biol Chem
, vol.277
, pp. 42399-42408
-
-
Yamashita, M.1
-
112
-
-
78650304399
-
The enhancer HS2 critically regulates GATA-3-mediated Il4 transcription in T(H)2 cells
-
Tanaka S., et al. The enhancer HS2 critically regulates GATA-3-mediated Il4 transcription in T(H)2 cells. Nat Immunol 2011, 12:77-85.
-
(2011)
Nat Immunol
, vol.12
, pp. 77-85
-
-
Tanaka, S.1
-
113
-
-
10344234192
-
Th2-specific chromatin remodeling and enhancer activity in the Th2 cytokine locus control region
-
Fields P.E., Lee G.R., Kim S.T., Bartsevich V.V., Flavell R.A. Th2-specific chromatin remodeling and enhancer activity in the Th2 cytokine locus control region. Immunity 2004, 21:865-876.
-
(2004)
Immunity
, vol.21
, pp. 865-876
-
-
Fields, P.E.1
Lee, G.R.2
Kim, S.T.3
Bartsevich, V.V.4
Flavell, R.A.5
-
114
-
-
0037963472
-
Regulation of the Th2 cytokine locus by a locus control region
-
Lee G.R., Fields P.E., Griffin T.J., Flavell R.A. Regulation of the Th2 cytokine locus by a locus control region. Immunity 2003, 19:145-153.
-
(2003)
Immunity
, vol.19
, pp. 145-153
-
-
Lee, G.R.1
Fields, P.E.2
Griffin, T.J.3
Flavell, R.A.4
-
115
-
-
0034665507
-
An intron transcriptional enhancer element regulates IL-4 gene locus accessibility in mast cells
-
Hural J.A., Kwan M., Henkel G., Hock M.B., Brown M.A. An intron transcriptional enhancer element regulates IL-4 gene locus accessibility in mast cells. J Immunol 2000, 165:3239-3249.
-
(2000)
J Immunol
, vol.165
, pp. 3239-3249
-
-
Hural, J.A.1
Kwan, M.2
Henkel, G.3
Hock, M.B.4
Brown, M.A.5
-
116
-
-
0035984591
-
A 3' enhancer in the IL-4 gene regulates cytokine production by Th2 cells and mast cells
-
Solymar D.C., Agarwal S., Bassing C.H., Alt F.W., Rao A. A 3' enhancer in the IL-4 gene regulates cytokine production by Th2 cells and mast cells. Immunity 2002, 17:41-50.
-
(2002)
Immunity
, vol.17
, pp. 41-50
-
-
Solymar, D.C.1
Agarwal, S.2
Bassing, C.H.3
Alt, F.W.4
Rao, A.5
-
117
-
-
31144460961
-
GATA-3 promotes Th2 responses through three different mechanisms: induction of Th2 cytokine production, selective growth of Th2 cells and inhibition of Th1 cell-specific factors
-
Zhu J., Yamane H., Cote-Sierra J., Guo L., Paul W.E. GATA-3 promotes Th2 responses through three different mechanisms: induction of Th2 cytokine production, selective growth of Th2 cells and inhibition of Th1 cell-specific factors. Cell Res 2006, 16:3-10.
-
(2006)
Cell Res
, vol.16
, pp. 3-10
-
-
Zhu, J.1
Yamane, H.2
Cote-Sierra, J.3
Guo, L.4
Paul, W.E.5
-
118
-
-
54549103162
-
Priming for T helper type 2 differentiation by interleukin 2-mediated induction of interleukin 4 receptor alpha-chain expression
-
Liao W., et al. Priming for T helper type 2 differentiation by interleukin 2-mediated induction of interleukin 4 receptor alpha-chain expression. Nat Immunol 2008, 9:1288-1296.
-
(2008)
Nat Immunol
, vol.9
, pp. 1288-1296
-
-
Liao, W.1
-
119
-
-
84879689439
-
Specificity through cooperation: BATF-IRF interactions control immune-regulatory networks
-
Murphy T.L., Tussiwand R., Murphy K.M. Specificity through cooperation: BATF-IRF interactions control immune-regulatory networks. Nat Rev Immunol 2013, 13:499-509.
-
(2013)
Nat Rev Immunol
, vol.13
, pp. 499-509
-
-
Murphy, T.L.1
Tussiwand, R.2
Murphy, K.M.3
-
120
-
-
84904397782
-
IRF4 at the crossroads of effector T-cell fate decision
-
Huber M., Lohoff M. IRF4 at the crossroads of effector T-cell fate decision. Eur J Immunol 2014, 44:1886-1895.
-
(2014)
Eur J Immunol
, vol.44
, pp. 1886-1895
-
-
Huber, M.1
Lohoff, M.2
-
121
-
-
0037015052
-
Dysregulated T helper cell differentiation in the absence of interferon regulatory factor 4
-
Lohoff M., et al. Dysregulated T helper cell differentiation in the absence of interferon regulatory factor 4. Proc Natl Acad Sci USA 2002, 99:11808-11812.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 11808-11812
-
-
Lohoff, M.1
-
122
-
-
0037089575
-
Interferon regulatory factor 4 (IRF4) interacts with NFATc2 to modulate interleukin 4 gene expression
-
Rengarajan J., et al. Interferon regulatory factor 4 (IRF4) interacts with NFATc2 to modulate interleukin 4 gene expression. J Exp Med 2002, 195:1003-1012.
-
(2002)
J Exp Med
, vol.195
, pp. 1003-1012
-
-
Rengarajan, J.1
-
123
-
-
34548128307
-
The development of inflammatory T(H)-17 cells requires interferon-regulatory factor 4
-
Brustle A., et al. The development of inflammatory T(H)-17 cells requires interferon-regulatory factor 4. Nat Immunol 2007, 8:958-966.
-
(2007)
Nat Immunol
, vol.8
, pp. 958-966
-
-
Brustle, A.1
-
124
-
-
62649165369
-
Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control T(H)2 responses
-
Zheng Y., et al. Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control T(H)2 responses. Nature 2009, 458:351-356.
-
(2009)
Nature
, vol.458
, pp. 351-356
-
-
Zheng, Y.1
-
125
-
-
77955902281
-
Interferon-regulatory factor 4 is essential for the developmental program of T helper 9 cells
-
Staudt V., et al. Interferon-regulatory factor 4 is essential for the developmental program of T helper 9 cells. Immunity 2010, 33:192-202.
-
(2010)
Immunity
, vol.33
, pp. 192-202
-
-
Staudt, V.1
-
126
-
-
84867581744
-
A validated regulatory network for Th17 cell specification
-
Ciofani M., et al. A validated regulatory network for Th17 cell specification. Cell 2012.
-
(2012)
Cell
-
-
Ciofani, M.1
-
127
-
-
84867861268
-
BATF-JUN is critical for IRF4-mediated transcription in T cells
-
Li P., et al. BATF-JUN is critical for IRF4-mediated transcription in T cells. Nature 2012, 490:543-546.
-
(2012)
Nature
, vol.490
, pp. 543-546
-
-
Li, P.1
-
128
-
-
84869116884
-
A genomic regulatory element that directs assembly and function of immune-specific AP-1-IRF complexes
-
Glasmacher E., et al. A genomic regulatory element that directs assembly and function of immune-specific AP-1-IRF complexes. Science (New York, NY) 2012, 338:975-980.
-
(2012)
Science (New York, NY)
, vol.338
, pp. 975-980
-
-
Glasmacher, E.1
-
129
-
-
73249149628
-
C-Maf regulates IL-10 expression during Th17 polarization
-
Xu J., et al. C-Maf regulates IL-10 expression during Th17 polarization. J Immunol 2009, 182:6226-6236.
-
(2009)
J Immunol
, vol.182
, pp. 6226-6236
-
-
Xu, J.1
-
130
-
-
81255136238
-
Transcription factor c-Maf mediates the TGF-beta-dependent suppression of IL-22 production in T(H)17 cells
-
Rutz S., et al. Transcription factor c-Maf mediates the TGF-beta-dependent suppression of IL-22 production in T(H)17 cells. Nat Immunol 2011, 12:1238-1245.
-
(2011)
Nat Immunol
, vol.12
, pp. 1238-1245
-
-
Rutz, S.1
-
131
-
-
58449124804
-
The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells
-
Bauquet A.T., et al. The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells. Nat Immunol 2009, 10:167-175.
-
(2009)
Nat Immunol
, vol.10
, pp. 167-175
-
-
Bauquet, A.T.1
-
132
-
-
0033152267
-
The transcription factor c-Maf controls the production of interleukin-4 but not other Th2 cytokines
-
Kim J.I., Ho I.C., Grusby M.J., Glimcher L.H. The transcription factor c-Maf controls the production of interleukin-4 but not other Th2 cytokines. Immunity 1999, 10:745-751.
-
(1999)
Immunity
, vol.10
, pp. 745-751
-
-
Kim, J.I.1
Ho, I.C.2
Grusby, M.J.3
Glimcher, L.H.4
-
133
-
-
84923446955
-
The long intergenic noncoding RNA landscape of human lymphocytes highlights the regulation of T cell differentiation by linc-MAF-4
-
Ranzani V., et al. The long intergenic noncoding RNA landscape of human lymphocytes highlights the regulation of T cell differentiation by linc-MAF-4. Nat Immunol 2015.
-
(2015)
Nat Immunol
-
-
Ranzani, V.1
-
134
-
-
84902158615
-
KLF13 cooperates with c-Maf to regulate IL-4 expression in CD4+ T cells
-
Kwon S.J., et al. KLF13 cooperates with c-Maf to regulate IL-4 expression in CD4+ T cells. J Immunol 2014, 192:5703-5709.
-
(2014)
J Immunol
, vol.192
, pp. 5703-5709
-
-
Kwon, S.J.1
-
135
-
-
79956133739
-
KLF13 sustains thymic memory-like CD8(+) T cells in BALB/c mice by regulating IL-4-generating invariant natural killer T cells
-
Lai D., et al. KLF13 sustains thymic memory-like CD8(+) T cells in BALB/c mice by regulating IL-4-generating invariant natural killer T cells. J Exp Med 2011, 208:1093-1103.
-
(2011)
J Exp Med
, vol.208
, pp. 1093-1103
-
-
Lai, D.1
-
136
-
-
70449707113
-
Requirement for the basic helix-loop-helix transcription factor Dec2 in initial TH2 lineage commitment
-
Yang X.O., et al. Requirement for the basic helix-loop-helix transcription factor Dec2 in initial TH2 lineage commitment. Nat Immunol 2009, 10:1260-1266.
-
(2009)
Nat Immunol
, vol.10
, pp. 1260-1266
-
-
Yang, X.O.1
-
137
-
-
73949134616
-
Nfil3/E4bp4 is required for the development and maturation of NK cells in vivo
-
Kamizono S., et al. Nfil3/E4bp4 is required for the development and maturation of NK cells in vivo. J Exp Med 2009, 206:2977-2986.
-
(2009)
J Exp Med
, vol.206
, pp. 2977-2986
-
-
Kamizono, S.1
-
138
-
-
70349446453
-
The basic leucine zipper transcription factor E4BP4 is essential for natural killer cell development
-
Gascoyne D.M., et al. The basic leucine zipper transcription factor E4BP4 is essential for natural killer cell development. Nat Immunol 2009, 10:1118-1124.
-
(2009)
Nat Immunol
, vol.10
, pp. 1118-1124
-
-
Gascoyne, D.M.1
-
139
-
-
84897943066
-
The transcription factor E4bp4/Nfil3 controls commitment to the NK lineage and directly regulates Eomes and Id2 expression
-
Male V., et al. The transcription factor E4bp4/Nfil3 controls commitment to the NK lineage and directly regulates Eomes and Id2 expression. J Exp Med 2014, 211:635-642.
-
(2014)
J Exp Med
, vol.211
, pp. 635-642
-
-
Male, V.1
-
140
-
-
84906534108
-
Nfil3 is crucial for development of innate lymphoid cells and host protection against intestinal pathogens
-
Geiger T.L., et al. Nfil3 is crucial for development of innate lymphoid cells and host protection against intestinal pathogens. J Exp Med 2014, 211:1723-1731.
-
(2014)
J Exp Med
, vol.211
, pp. 1723-1731
-
-
Geiger, T.L.1
-
141
-
-
84906568567
-
Nfil3 is required for the development of all innate lymphoid cell subsets
-
Seillet C., et al. Nfil3 is required for the development of all innate lymphoid cell subsets. J Exp Med 2014, 211:1733-1740.
-
(2014)
J Exp Med
, vol.211
, pp. 1733-1740
-
-
Seillet, C.1
-
142
-
-
85017120517
-
The basic leucine zipper transcription factor NFIL3 directs the development of a common innate lymphoid cell precursor
-
Yu X., et al. The basic leucine zipper transcription factor NFIL3 directs the development of a common innate lymphoid cell precursor. eLife 2014, 3.
-
(2014)
eLife
, pp. 3
-
-
Yu, X.1
-
143
-
-
79954992071
-
The transcription factor E4BP4 regulates the production of IL-10 and IL-13 in CD4+ T cells
-
Motomura Y., et al. The transcription factor E4BP4 regulates the production of IL-10 and IL-13 in CD4+ T cells. Nat Immunol 2011, 12:450-459.
-
(2011)
Nat Immunol
, vol.12
, pp. 450-459
-
-
Motomura, Y.1
-
144
-
-
84871948166
-
Transcription factor YY1 is essential for regulation of the Th2 cytokine locus and for Th2 cell differentiation
-
Hwang S.S., et al. Transcription factor YY1 is essential for regulation of the Th2 cytokine locus and for Th2 cell differentiation. Proc Natl Acad Sci USA 2013, 110:276-281.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 276-281
-
-
Hwang, S.S.1
-
145
-
-
33846489173
-
Transcription factors T-bet and Runx3 cooperate to activate Ifng and silence Il4 in T helper type 1 cells
-
Djuretic I.M., et al. Transcription factors T-bet and Runx3 cooperate to activate Ifng and silence Il4 in T helper type 1 cells. Nat Immunol 2007, 8:145-153.
-
(2007)
Nat Immunol
, vol.8
, pp. 145-153
-
-
Djuretic, I.M.1
-
146
-
-
77951920474
-
The transcription factor GATA3 actively represses RUNX3 protein-regulated production of interferon-gamma
-
Yagi R., et al. The transcription factor GATA3 actively represses RUNX3 protein-regulated production of interferon-gamma. Immunity 2010, 32:507-517.
-
(2010)
Immunity
, vol.32
, pp. 507-517
-
-
Yagi, R.1
-
147
-
-
34547727747
-
Repression of interleukin-4 in T helper type 1 cells by Runx/Cbf beta binding to the Il4 silencer
-
Naoe Y., et al. Repression of interleukin-4 in T helper type 1 cells by Runx/Cbf beta binding to the Il4 silencer. J Exp Med 2007, 204:1749-1755.
-
(2007)
J Exp Med
, vol.204
, pp. 1749-1755
-
-
Naoe, Y.1
-
148
-
-
82055197492
-
Eomesodermin controls interleukin-5 production in memory T helper 2 cells through inhibition of activity of the transcription factor GATA3
-
Endo Y., et al. Eomesodermin controls interleukin-5 production in memory T helper 2 cells through inhibition of activity of the transcription factor GATA3. Immunity 2011, 35:733-745.
-
(2011)
Immunity
, vol.35
, pp. 733-745
-
-
Endo, Y.1
-
149
-
-
84864131152
-
The transcription factor Sox4 is a downstream target of signaling by the cytokine TGF-beta and suppresses T(H)2 differentiation
-
Kuwahara M., et al. The transcription factor Sox4 is a downstream target of signaling by the cytokine TGF-beta and suppresses T(H)2 differentiation. Nat Immunol 2012, 13:778-786.
-
(2012)
Nat Immunol
, vol.13
, pp. 778-786
-
-
Kuwahara, M.1
-
150
-
-
20444502955
-
PU.1 expression delineates heterogeneity in primary Th2 cells
-
Chang H.C., et al. PU.1 expression delineates heterogeneity in primary Th2 cells. Immunity 2005, 22:693-703.
-
(2005)
Immunity
, vol.22
, pp. 693-703
-
-
Chang, H.C.1
-
151
-
-
80555136815
-
GATA3 controls Foxp3(+) regulatory T cell fate during inflammation in mice
-
Wohlfert E.A., et al. GATA3 controls Foxp3(+) regulatory T cell fate during inflammation in mice. J Clin Investig 2011, 121:4503-4515.
-
(2011)
J Clin Investig
, vol.121
, pp. 4503-4515
-
-
Wohlfert, E.A.1
-
152
-
-
80053130719
-
An essential role of the transcription factor GATA-3 for the function of regulatory T cells
-
Wang Y., Su M.A., Wan Y.Y. An essential role of the transcription factor GATA-3 for the function of regulatory T cells. Immunity 2011, 35:337-348.
-
(2011)
Immunity
, vol.35
, pp. 337-348
-
-
Wang, Y.1
Su, M.A.2
Wan, Y.Y.3
-
153
-
-
84866548843
-
Transcription factor Foxp3 and its protein partners form a complex regulatory network
-
Rudra D., et al. Transcription factor Foxp3 and its protein partners form a complex regulatory network. Nat Immunol 2012, 13:1010-1019.
-
(2012)
Nat Immunol
, vol.13
, pp. 1010-1019
-
-
Rudra, D.1
-
154
-
-
84923035090
-
Dynamic expression of transcription factors T-bet and GATA-3 by regulatory T cells maintains immunotolerance
-
Yu F., Sharma S., Edwards J., Feigenbaum L., Zhu J. Dynamic expression of transcription factors T-bet and GATA-3 by regulatory T cells maintains immunotolerance. Nat Immunol 2015, 16:197-206.
-
(2015)
Nat Immunol
, vol.16
, pp. 197-206
-
-
Yu, F.1
Sharma, S.2
Edwards, J.3
Feigenbaum, L.4
Zhu, J.5
-
155
-
-
33847125247
-
Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression
-
Wan Y.S.Y., Flavell R.A. Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression. Nature 2007, 445:766-770.
-
(2007)
Nature
, vol.445
, pp. 766-770
-
-
Wan, Y.S.Y.1
Flavell, R.A.2
-
156
-
-
20844432429
-
Analysis of FOXP3 protein expression in human CD4+CD25+ regulatory T cells at the single-cell level
-
Roncador G., et al. Analysis of FOXP3 protein expression in human CD4+CD25+ regulatory T cells at the single-cell level. Eur J Immunol 2005, 35:1681-1691.
-
(2005)
Eur J Immunol
, vol.35
, pp. 1681-1691
-
-
Roncador, G.1
-
157
-
-
35448930435
-
Induction of FOXP3 expression in naive human CD4+FOXP3 T cells by T-cell receptor stimulation is transforming growth factor-beta dependent but does not confer a regulatory phenotype
-
Tran D.Q., Ramsey H., Shevach E.M. Induction of FOXP3 expression in naive human CD4+FOXP3 T cells by T-cell receptor stimulation is transforming growth factor-beta dependent but does not confer a regulatory phenotype. Blood 2007, 110:2983-2990.
-
(2007)
Blood
, vol.110
, pp. 2983-2990
-
-
Tran, D.Q.1
Ramsey, H.2
Shevach, E.M.3
-
158
-
-
79955364415
-
An NK and T cell enhancer lies 280 kilobase pairs 3' to the gata3 structural gene
-
Hosoya-Ohmura S., et al. An NK and T cell enhancer lies 280 kilobase pairs 3' to the gata3 structural gene. Mol Cell Biol 2011, 31:1894-1904.
-
(2011)
Mol Cell Biol
, vol.31
, pp. 1894-1904
-
-
Hosoya-Ohmura, S.1
-
159
-
-
84886724189
-
Expression and regulation of intergenic long noncoding RNAs during T cell development and differentiation
-
Hu G., et al. Expression and regulation of intergenic long noncoding RNAs during T cell development and differentiation. Nat Immunol 2013, 14:1190-1198.
-
(2013)
Nat Immunol
, vol.14
, pp. 1190-1198
-
-
Hu, G.1
-
160
-
-
0034897188
-
The basis for IL-2-induced IL-2 receptor alpha chain gene regulation: importance of two widely separated IL-2 response elements
-
Kim H.P., Kelly J., Leonard W.J. The basis for IL-2-induced IL-2 receptor alpha chain gene regulation: importance of two widely separated IL-2 response elements. Immunity 2001, 15:159-172.
-
(2001)
Immunity
, vol.15
, pp. 159-172
-
-
Kim, H.P.1
Kelly, J.2
Leonard, W.J.3
-
161
-
-
84907308588
-
Revisiting thymic positive selection and the mature T cell repertoire for antigen
-
Vrisekoop N., Monteiro J.P., Mandl J.N., Germain R.N. Revisiting thymic positive selection and the mature T cell repertoire for antigen. Immunity 2014, 41:181-190.
-
(2014)
Immunity
, vol.41
, pp. 181-190
-
-
Vrisekoop, N.1
Monteiro, J.P.2
Mandl, J.N.3
Germain, R.N.4
-
162
-
-
0037342749
-
GATA-3 suppresses Th1 development by downregulation of Stat4 and not through effects on IL-12Rbeta2 chain or T-bet
-
Usui T., Nishikomori R., Kitani A., Strober W. GATA-3 suppresses Th1 development by downregulation of Stat4 and not through effects on IL-12Rbeta2 chain or T-bet. Immunity 2003, 18:415-428.
-
(2003)
Immunity
, vol.18
, pp. 415-428
-
-
Usui, T.1
Nishikomori, R.2
Kitani, A.3
Strober, W.4
-
163
-
-
0242410712
-
Control of effector CD8+ T cell function by the transcription factor Eomesodermin
-
Pearce E.L., et al. Control of effector CD8+ T cell function by the transcription factor Eomesodermin. Science (New York, NY) 2003, 302:1041-1043.
-
(2003)
Science (New York, NY)
, vol.302
, pp. 1041-1043
-
-
Pearce, E.L.1
-
164
-
-
12344269852
-
T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3
-
Hwang E.S., Szabo S.J., Schwartzberg P.L., Glimcher L.H. T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3. Science (New York, NY) 2005, 307:430-433.
-
(2005)
Science (New York, NY)
, vol.307
, pp. 430-433
-
-
Hwang, E.S.1
Szabo, S.J.2
Schwartzberg, P.L.3
Glimcher, L.H.4
-
165
-
-
84880949850
-
Stable T-bet(+)GATA-3(+) Th1/Th2 hybrid cells arise in vivo, can develop directly from naive precursors, and limit immunopathologic inflammation
-
Peine M., et al. Stable T-bet(+)GATA-3(+) Th1/Th2 hybrid cells arise in vivo, can develop directly from naive precursors, and limit immunopathologic inflammation. PLoS Biol 2013, 11:e1001633.
-
(2013)
PLoS Biol
, vol.11
, pp. e1001633
-
-
Peine, M.1
-
166
-
-
84871783406
-
T-bet and GATA3 orchestrate Th1 and Th2 differentiation through lineage-specific targeting of distal regulatory elements
-
Kanhere A., et al. T-bet and GATA3 orchestrate Th1 and Th2 differentiation through lineage-specific targeting of distal regulatory elements. Nat Commun 2012, 3:1268.
-
(2012)
Nat Commun
, vol.3
, pp. 1268
-
-
Kanhere, A.1
-
167
-
-
33947162110
-
Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation
-
Laurence A., et al. Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation. Immunity 2007, 26:371-381.
-
(2007)
Immunity
, vol.26
, pp. 371-381
-
-
Laurence, A.1
-
168
-
-
84863116170
-
STAT5 is a potent negative regulator of TFH cell differentiation
-
Johnston R.J., Choi Y.S., Diamond J.A., Yang J.A., Crotty S. STAT5 is a potent negative regulator of TFH cell differentiation. J Exp Med 2012, 209:243-250.
-
(2012)
J Exp Med
, vol.209
, pp. 243-250
-
-
Johnston, R.J.1
Choi, Y.S.2
Diamond, J.A.3
Yang, J.A.4
Crotty, S.5
-
169
-
-
84861423126
-
Interleukin-2 inhibits germinal center formation by limiting T follicular helper cell differentiation
-
Ballesteros-Tato A., et al. Interleukin-2 inhibits germinal center formation by limiting T follicular helper cell differentiation. Immunity 2012, 36:847-856.
-
(2012)
Immunity
, vol.36
, pp. 847-856
-
-
Ballesteros-Tato, A.1
-
170
-
-
84872790689
-
Interleukin-2 at the crossroads of effector responses, tolerance, and immunotherapy
-
Liao W., Lin J.X., Leonard W.J. Interleukin-2 at the crossroads of effector responses, tolerance, and immunotherapy. Immunity 2013, 38:13-25.
-
(2013)
Immunity
, vol.38
, pp. 13-25
-
-
Liao, W.1
Lin, J.X.2
Leonard, W.J.3
-
171
-
-
84867714627
-
Cytokines of the gamma(c) family control CD4+ T cell differentiation and function
-
Yamane H., Paul W.E. Cytokines of the gamma(c) family control CD4+ T cell differentiation and function. Nat Immunol 2012, 13:1037-1044.
-
(2012)
Nat Immunol
, vol.13
, pp. 1037-1044
-
-
Yamane, H.1
Paul, W.E.2
-
172
-
-
33845285520
-
Gfi-1 plays an important role in IL-2-mediated Th2 cell expansion
-
Zhu J., Jankovic D., Grinberg A., Guo L., Paul W.E. Gfi-1 plays an important role in IL-2-mediated Th2 cell expansion. Proc Natl Acad Sci USA 2006, 103:18214-18219.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 18214-18219
-
-
Zhu, J.1
Jankovic, D.2
Grinberg, A.3
Guo, L.4
Paul, W.E.5
-
173
-
-
63049109925
-
Down-regulation of Gfi-1 expression by TGF-beta is important for differentiation of Th17 and CD103+ inducible regulatory T cells
-
Zhu J., et al. Down-regulation of Gfi-1 expression by TGF-beta is important for differentiation of Th17 and CD103+ inducible regulatory T cells. J Exp Med 2009, 206:329-341.
-
(2009)
J Exp Med
, vol.206
, pp. 329-341
-
-
Zhu, J.1
-
174
-
-
0036284957
-
Growth factor independent-1 induced by IL-4 regulates Th2 cell proliferation
-
Zhu J., et al. Growth factor independent-1 induced by IL-4 regulates Th2 cell proliferation. Immunity 2002, 16:733-744.
-
(2002)
Immunity
, vol.16
, pp. 733-744
-
-
Zhu, J.1
-
175
-
-
8044250881
-
Regulation of the interleukin (IL)-12R beta 2 subunit expression in developing T helper 1 (Th1) and Th2 cells
-
Szabo S.J., Dighe A.S., Gubler U., Murphy K.M. Regulation of the interleukin (IL)-12R beta 2 subunit expression in developing T helper 1 (Th1) and Th2 cells. J Exp Med 1997, 185:817-824.
-
(1997)
J Exp Med
, vol.185
, pp. 817-824
-
-
Szabo, S.J.1
Dighe, A.S.2
Gubler, U.3
Murphy, K.M.4
-
176
-
-
0035827347
-
Role of T-bet in commitment of TH1 cells before IL-12-dependent selection
-
Mullen A.C., et al. Role of T-bet in commitment of TH1 cells before IL-12-dependent selection. Science (New York, NY) 2001, 292:1907-1910.
-
(2001)
Science (New York, NY)
, vol.292
, pp. 1907-1910
-
-
Mullen, A.C.1
-
177
-
-
0025822170
-
IL-4-dependent up-regulation of IL-4 receptor expression in murine T and B cells
-
Renz H., Domenico J., Gelfand E.W. IL-4-dependent up-regulation of IL-4 receptor expression in murine T and B cells. J Immunol 1991, 146:3049-3055.
-
(1991)
J Immunol
, vol.146
, pp. 3049-3055
-
-
Renz, H.1
Domenico, J.2
Gelfand, E.W.3
-
178
-
-
0036792086
-
An IL-4-independent and CD25-mediated function of c-maf in promoting the production of Th2 cytokines
-
Hwang E.S., White I.A., Ho I.C. An IL-4-independent and CD25-mediated function of c-maf in promoting the production of Th2 cytokines. Proc Natl Acad Sci USA 2002, 99:13026-13030.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 13026-13030
-
-
Hwang, E.S.1
White, I.A.2
Ho, I.C.3
-
179
-
-
2642610290
-
Selective expression of a stable cell surface molecule on type 2 but not type 1 helper T cells
-
Xu D., et al. Selective expression of a stable cell surface molecule on type 2 but not type 1 helper T cells. J Exp Med 1998, 187:787-794.
-
(1998)
J Exp Med
, vol.187
, pp. 787-794
-
-
Xu, D.1
-
180
-
-
0032499678
-
T1/ST2 is preferentially expressed on murine Th2 cells, independent of interleukin 4, interleukin 5, and interleukin 10, and important for Th2 effector function
-
Lohning M., et al. T1/ST2 is preferentially expressed on murine Th2 cells, independent of interleukin 4, interleukin 5, and interleukin 10, and important for Th2 effector function. Proc Natl Acad Sci USA 1998, 95:6930-6935.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 6930-6935
-
-
Lohning, M.1
-
181
-
-
0034689033
-
T1/ST2-deficient mice demonstrate the importance of T1/ST2 in developing primary T helper cell type 2 responses
-
Townsend M.J., Fallon P.G., Matthews D.J., Jolin H.E., McKenzie A.N. T1/ST2-deficient mice demonstrate the importance of T1/ST2 in developing primary T helper cell type 2 responses. J Exp Med 2000, 191:1069-1076.
-
(2000)
J Exp Med
, vol.191
, pp. 1069-1076
-
-
Townsend, M.J.1
Fallon, P.G.2
Matthews, D.J.3
Jolin, H.E.4
McKenzie, A.N.5
-
182
-
-
5444237577
-
Long-range intrachromosomal interactions in the T helper type 2 cytokine locus
-
Spilianakis C.G., Flavell R.A. Long-range intrachromosomal interactions in the T helper type 2 cytokine locus. Nat Immunol 2004, 5:1017-1027.
-
(2004)
Nat Immunol
, vol.5
, pp. 1017-1027
-
-
Spilianakis, C.G.1
Flavell, R.A.2
-
183
-
-
58849092225
-
Epigenetic control of T-helper-cell differentiation
-
Wilson C.B., Rowell E., Sekimata M. Epigenetic control of T-helper-cell differentiation. Nat Rev Immunol 2009, 9:91-105.
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 91-105
-
-
Wilson, C.B.1
Rowell, E.2
Sekimata, M.3
-
184
-
-
84859401055
-
Transcriptional and epigenetic control of T helper cell specification: molecular mechanisms underlying commitment and plasticity
-
Kanno Y., Vahedi G., Hirahara K., Singleton K., O'Shea J.J. Transcriptional and epigenetic control of T helper cell specification: molecular mechanisms underlying commitment and plasticity. Annu Rev Immunol 2012, 30:707-731.
-
(2012)
Annu Rev Immunol
, vol.30
, pp. 707-731
-
-
Kanno, Y.1
Vahedi, G.2
Hirahara, K.3
Singleton, K.4
O'Shea, J.J.5
-
185
-
-
0032412441
-
Modulation of chromatin structure regulates cytokine gene expression during T cell differentiation
-
Agarwal S., Rao A. Modulation of chromatin structure regulates cytokine gene expression during T cell differentiation. Immunity 1998, 9:765-775.
-
(1998)
Immunity
, vol.9
, pp. 765-775
-
-
Agarwal, S.1
Rao, A.2
-
186
-
-
0026467244
-
A DNase I-hypersensitive site in the second intron of the murine IL-4 gene defines a mast cell-specific enhancer
-
Henkel G., et al. A DNase I-hypersensitive site in the second intron of the murine IL-4 gene defines a mast cell-specific enhancer. J Immunol 1992, 149:3239-3246.
-
(1992)
J Immunol
, vol.149
, pp. 3239-3246
-
-
Henkel, G.1
-
187
-
-
0034616398
-
Identification of a coordinate regulator of interleukins 4, 13, and 5 by cross-species sequence comparisons
-
Loots G.G., et al. Identification of a coordinate regulator of interleukins 4, 13, and 5 by cross-species sequence comparisons. Science (New York, NY) 2000, 288:136-140.
-
(2000)
Science (New York, NY)
, vol.288
, pp. 136-140
-
-
Loots, G.G.1
-
188
-
-
0035555263
-
Deletion of a coordinate regulator of type 2 cytokine expression in mice
-
Mohrs M., et al. Deletion of a coordinate regulator of type 2 cytokine expression in mice. Nat Immunol 2001, 2:842-847.
-
(2001)
Nat Immunol
, vol.2
, pp. 842-847
-
-
Mohrs, M.1
-
189
-
-
36749029364
-
Demethylation of a specific hypersensitive site in the Th2 locus control region
-
Kim S.T., Fields P.E., Flavell R.A. Demethylation of a specific hypersensitive site in the Th2 locus control region. Proc Natl Acad Sci USA 2007, 104:17052-17057.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 17052-17057
-
-
Kim, S.T.1
Fields, P.E.2
Flavell, R.A.3
-
190
-
-
12344308991
-
Deletion of a conserved Il4 silencer impairs T helper type 1-mediated immunity
-
Ansel K.M., et al. Deletion of a conserved Il4 silencer impairs T helper type 1-mediated immunity. Nat Immunol 2004, 5:1251-1259.
-
(2004)
Nat Immunol
, vol.5
, pp. 1251-1259
-
-
Ansel, K.M.1
-
191
-
-
12344250807
-
Hypersensitive site 7 of the TH2 locus control region is essential for expressing TH2 cytokine genes and for long-range intrachromosomal interactions
-
Lee G.R., Spilianakis C.G., Flavell R.A. Hypersensitive site 7 of the TH2 locus control region is essential for expressing TH2 cytokine genes and for long-range intrachromosomal interactions. Nat Immunol 2005, 6:42-48.
-
(2005)
Nat Immunol
, vol.6
, pp. 42-48
-
-
Lee, G.R.1
Spilianakis, C.G.2
Flavell, R.A.3
-
192
-
-
84876841993
-
Hypersensitive site 6 of the Th2 locus control region is essential for Th2 cytokine expression
-
Williams A., et al. Hypersensitive site 6 of the Th2 locus control region is essential for Th2 cytokine expression. Proc Natl Acad Sci USA 2013, 110:6955-6960.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 6955-6960
-
-
Williams, A.1
-
193
-
-
77953789765
-
Th2 LCR is essential for regulation of Th2 cytokine genes and for pathogenesis of allergic asthma
-
Koh B.H., et al. Th2 LCR is essential for regulation of Th2 cytokine genes and for pathogenesis of allergic asthma. Proc Natl Acad Sci USA 2010, 107:10614-10619.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 10614-10619
-
-
Koh, B.H.1
-
194
-
-
34249026300
-
High-resolution profiling of histone methylations in the human genome
-
Barski A., et al. High-resolution profiling of histone methylations in the human genome. Cell 2007, 129:823-837.
-
(2007)
Cell
, vol.129
, pp. 823-837
-
-
Barski, A.1
-
195
-
-
58149214356
-
Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells
-
Wei G., et al. Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells. Immunity 2009, 30:155-167.
-
(2009)
Immunity
, vol.30
, pp. 155-167
-
-
Wei, G.1
-
196
-
-
33646586637
-
Crucial role of MLL for the maintenance of memory T helper type 2 cell responses
-
Yamashita M., et al. Crucial role of MLL for the maintenance of memory T helper type 2 cell responses. Immunity 2006, 24:611-622.
-
(2006)
Immunity
, vol.24
, pp. 611-622
-
-
Yamashita, M.1
-
197
-
-
24744462507
-
EZH2 and histone 3 trimethyl lysine 27 associated with Il4 and Il13 gene silencing in Th1 cells
-
Koyanagi M., et al. EZH2 and histone 3 trimethyl lysine 27 associated with Il4 and Il13 gene silencing in Th1 cells. J Biol Chem 2005, 280:31470-31477.
-
(2005)
J Biol Chem
, vol.280
, pp. 31470-31477
-
-
Koyanagi, M.1
-
198
-
-
84887549060
-
The polycomb protein Ezh2 regulates differentiation and plasticity of CD4(+) T helper type 1 and type 2 cells
-
Tumes D.J., et al. The polycomb protein Ezh2 regulates differentiation and plasticity of CD4(+) T helper type 1 and type 2 cells. Immunity 2013, 39:819-832.
-
(2013)
Immunity
, vol.39
, pp. 819-832
-
-
Tumes, D.J.1
-
199
-
-
78149322622
-
STAT6-mediated displacement of polycomb by trithorax complex establishes long-term maintenance of GATA3 expression in T helper type 2 cells
-
Onodera A., et al. STAT6-mediated displacement of polycomb by trithorax complex establishes long-term maintenance of GATA3 expression in T helper type 2 cells. J Exp Med 2010, 207:2493-2506.
-
(2010)
J Exp Med
, vol.207
, pp. 2493-2506
-
-
Onodera, A.1
-
200
-
-
0036305450
-
T-H cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes
-
Avni O., et al. T-H cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes. Nat Immunol 2002, 3:643-651.
-
(2002)
Nat Immunol
, vol.3
, pp. 643-651
-
-
Avni, O.1
-
201
-
-
0028858399
-
Activation of the interleukin-5 promoter by cAMP in murine EL-4 cells requires the GATA-3 and CLE0 elements
-
Siegel M.D., Zhang D.H., Ray P., Ray A. Activation of the interleukin-5 promoter by cAMP in murine EL-4 cells requires the GATA-3 and CLE0 elements. J Biol Chem 1995, 270:24548-24555.
-
(1995)
J Biol Chem
, vol.270
, pp. 24548-24555
-
-
Siegel, M.D.1
Zhang, D.H.2
Ray, P.3
Ray, A.4
-
202
-
-
0035887640
-
The cell type-specific expression of the murine IL-13 gene is regulated by GATA-3
-
Kishikawa H., Sun J., Choi A., Miaw S.C., Ho I.C. The cell type-specific expression of the murine IL-13 gene is regulated by GATA-3. J Immunol 2001, 167:4414-4420.
-
(2001)
J Immunol
, vol.167
, pp. 4414-4420
-
-
Kishikawa, H.1
Sun, J.2
Choi, A.3
Miaw, S.C.4
Ho, I.C.5
-
203
-
-
2442588675
-
IL-4-induced GATA-3 expression is a time-restricted instruction switch for Th2 cell differentiation
-
Seki N., et al. IL-4-induced GATA-3 expression is a time-restricted instruction switch for Th2 cell differentiation. J Immunol 2004, 172:6158-6166.
-
(2004)
J Immunol
, vol.172
, pp. 6158-6166
-
-
Seki, N.1
-
204
-
-
0000344022
-
GATA-3 induces T helper cell type 2 (Th2) cytokine expression and chromatin remodeling in committed Th1 cells
-
Lee H.J., et al. GATA-3 induces T helper cell type 2 (Th2) cytokine expression and chromatin remodeling in committed Th1 cells. J Exp Med 2000, 192:105-115.
-
(2000)
J Exp Med
, vol.192
, pp. 105-115
-
-
Lee, H.J.1
-
205
-
-
0036279221
-
Th2 lineage commitment and efficient IL-4 production involves extended demethylation of the IL-4 gene
-
Lee D.U., Agarwal S., Rao A. Th2 lineage commitment and efficient IL-4 production involves extended demethylation of the IL-4 gene. Immunity 2002, 16:649-660.
-
(2002)
Immunity
, vol.16
, pp. 649-660
-
-
Lee, D.U.1
Agarwal, S.2
Rao, A.3
-
206
-
-
0346752253
-
Active recruitment of DNA methyltransferases regulates interleukin 4 in thymocytes and T cells
-
Makar K.W., et al. Active recruitment of DNA methyltransferases regulates interleukin 4 in thymocytes and T cells. Nat Immunol 2003, 4:1183-1190.
-
(2003)
Nat Immunol
, vol.4
, pp. 1183-1190
-
-
Makar, K.W.1
-
207
-
-
0036345455
-
Gene silencing quantitatively controls the function of a developmental trans-activator
-
Hutchins A.S., et al. Gene silencing quantitatively controls the function of a developmental trans-activator. Mol Cell 2002, 10:81-91.
-
(2002)
Mol Cell
, vol.10
, pp. 81-91
-
-
Hutchins, A.S.1
-
208
-
-
0030973579
-
Transcription factors of the NFAT family: regulation and function
-
Rao A., Luo C., Hogan P.G. Transcription factors of the NFAT family: regulation and function. Annu Rev Immunol 1997, 15:707-747.
-
(1997)
Annu Rev Immunol
, vol.15
, pp. 707-747
-
-
Rao, A.1
Luo, C.2
Hogan, P.G.3
-
209
-
-
0033667895
-
Cell-type-restricted binding of the transcription factor NFAT to a distal IL-4 enhancer in vivo
-
Agarwal S., Avni O., Rao A. Cell-type-restricted binding of the transcription factor NFAT to a distal IL-4 enhancer in vivo. Immunity 2000, 12:643-652.
-
(2000)
Immunity
, vol.12
, pp. 643-652
-
-
Agarwal, S.1
Avni, O.2
Rao, A.3
-
210
-
-
0036144744
-
NFATc2 and NFATc3 regulate T(H)2 differentiation and modulate TCR-responsiveness of naive T(H)cells
-
Rengarajan J., Tang B., Glimcher L.H. NFATc2 and NFATc3 regulate T(H)2 differentiation and modulate TCR-responsiveness of naive T(H)cells. Nat Immunol 2002, 3:48-54.
-
(2002)
Nat Immunol
, vol.3
, pp. 48-54
-
-
Rengarajan, J.1
Tang, B.2
Glimcher, L.H.3
-
211
-
-
0030694235
-
IGIF does not drive Th1 development but synergizes with IL-12 for interferon-gamma production and activates IRAK and NFkappaB
-
Robinson D., et al. IGIF does not drive Th1 development but synergizes with IL-12 for interferon-gamma production and activates IRAK and NFkappaB. Immunity 1997, 7:571-581.
-
(1997)
Immunity
, vol.7
, pp. 571-581
-
-
Robinson, D.1
-
212
-
-
0035261399
-
IL-18-stimulated GADD45 beta required in cytokine-induced, but not TCR-induced, IFN-gamma production
-
Yang J., Zhu H., Murphy T.L., Ouyang W., Murphy K.M. IL-18-stimulated GADD45 beta required in cytokine-induced, but not TCR-induced, IFN-gamma production. Nat Immunol 2001, 2:157-164.
-
(2001)
Nat Immunol
, vol.2
, pp. 157-164
-
-
Yang, J.1
Zhu, H.2
Murphy, T.L.3
Ouyang, W.4
Murphy, K.M.5
-
213
-
-
84862832756
-
Human T(H)2 cells respond to cysteinyl leukotrienes through selective expression of cysteinyl leukotriene receptor 1
-
Parmentier C.N., et al. Human T(H)2 cells respond to cysteinyl leukotrienes through selective expression of cysteinyl leukotriene receptor 1. J Allergy Clin Immunol 2012, 129:1136-1142.
-
(2012)
J Allergy Clin Immunol
, vol.129
, pp. 1136-1142
-
-
Parmentier, C.N.1
-
214
-
-
84856004704
-
Leukotriene E4 activates human Th2 cells for exaggerated proinflammatory cytokine production in response to prostaglandin D2
-
Xue L., et al. Leukotriene E4 activates human Th2 cells for exaggerated proinflammatory cytokine production in response to prostaglandin D2. J Immunol 2012, 188:694-702.
-
(2012)
J Immunol
, vol.188
, pp. 694-702
-
-
Xue, L.1
-
215
-
-
22544448418
-
Probabilistic regulation in TH2 cells accounts for monoallelic expression of IL-4 and IL-13
-
Guo L., Hu-Li J., Paul W.E. Probabilistic regulation in TH2 cells accounts for monoallelic expression of IL-4 and IL-13. Immunity 2005, 23:89-99.
-
(2005)
Immunity
, vol.23
, pp. 89-99
-
-
Guo, L.1
Hu-Li, J.2
Paul, W.E.3
-
216
-
-
0036667345
-
In TH2 cells the Il4 gene has a series of accessibility states associated with distinctive probabilities of IL-4 production
-
Guo L., et al. In TH2 cells the Il4 gene has a series of accessibility states associated with distinctive probabilities of IL-4 production. Proc Natl Acad Sci USA 2002, 99:10623-10628.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 10623-10628
-
-
Guo, L.1
-
217
-
-
1342265727
-
Probabilistic regulation of IL-4 production in Th2 cells: accessibility at the Il4 locus
-
Guo L., Hu-Li J., Paul W.E. Probabilistic regulation of IL-4 production in Th2 cells: accessibility at the Il4 locus. Immunity 2004, 20:193-203.
-
(2004)
Immunity
, vol.20
, pp. 193-203
-
-
Guo, L.1
Hu-Li, J.2
Paul, W.E.3
-
218
-
-
84907572375
-
Nuclear factor of activated T cells regulates the expression of interleukin-4 in Th2 cells in an all-or-none fashion
-
Kock J., et al. Nuclear factor of activated T cells regulates the expression of interleukin-4 in Th2 cells in an all-or-none fashion. J Biol Chem 2014, 289:26752-26761.
-
(2014)
J Biol Chem
, vol.289
, pp. 26752-26761
-
-
Kock, J.1
-
219
-
-
84921292320
-
Individual T helper cells have a quantitative cytokine memory
-
Helmstetter C., et al. Individual T helper cells have a quantitative cytokine memory. Immunity 2015, 42:108-122.
-
(2015)
Immunity
, vol.42
, pp. 108-122
-
-
Helmstetter, C.1
-
220
-
-
62849090439
-
Cytokine-secreting follicular T cells shape the antibody repertoire
-
Reinhardt R.L., Liang H.E., Locksley R.M. Cytokine-secreting follicular T cells shape the antibody repertoire. Nat Immunol 2009, 10:385-393.
-
(2009)
Nat Immunol
, vol.10
, pp. 385-393
-
-
Reinhardt, R.L.1
Liang, H.E.2
Locksley, R.M.3
-
221
-
-
65549134481
-
T follicular helper cells differentiate from Th2 cells in response to helminth antigens
-
Zaretsky A.G., et al. T follicular helper cells differentiate from Th2 cells in response to helminth antigens. J Exp Med 2009, 206:991-999.
-
(2009)
J Exp Med
, vol.206
, pp. 991-999
-
-
Zaretsky, A.G.1
-
222
-
-
65549114338
-
IL-4-producing CD4+ T cells in reactive lymph nodes during helminth infection are T follicular helper cells
-
King I.L., Mohrs M. IL-4-producing CD4+ T cells in reactive lymph nodes during helminth infection are T follicular helper cells. J Exp Med 2009, 206:1001-1007.
-
(2009)
J Exp Med
, vol.206
, pp. 1001-1007
-
-
King, I.L.1
Mohrs, M.2
-
223
-
-
77955280012
-
Germinal center T follicular helper cell IL-4 production is dependent on signaling lymphocytic activation molecule receptor (CD150)
-
Yusuf I., et al. Germinal center T follicular helper cell IL-4 production is dependent on signaling lymphocytic activation molecule receptor (CD150). J Immunol 2010, 185:190-202.
-
(2010)
J Immunol
, vol.185
, pp. 190-202
-
-
Yusuf, I.1
-
224
-
-
84859487740
-
STAT5 protein negatively regulates T follicular helper (Tfh) cell generation and function
-
Nurieva R.I., et al. STAT5 protein negatively regulates T follicular helper (Tfh) cell generation and function. J Biol Chem 2012, 287:11234-11239.
-
(2012)
J Biol Chem
, vol.287
, pp. 11234-11239
-
-
Nurieva, R.I.1
-
225
-
-
84857398262
-
The 3' enhancer CNS2 is a critical regulator of interleukin-4-mediated humoral immunity in follicular helper T cells
-
Harada Y., et al. The 3' enhancer CNS2 is a critical regulator of interleukin-4-mediated humoral immunity in follicular helper T cells. Immunity 2012, 36:188-200.
-
(2012)
Immunity
, vol.36
, pp. 188-200
-
-
Harada, Y.1
-
226
-
-
84863393256
-
Interleukin-4 production by follicular helper T cells requires the conserved Il4 enhancer hypersensitivity site V
-
Vijayanand P., et al. Interleukin-4 production by follicular helper T cells requires the conserved Il4 enhancer hypersensitivity site V. Immunity 2012, 36:175-187.
-
(2012)
Immunity
, vol.36
, pp. 175-187
-
-
Vijayanand, P.1
-
227
-
-
80755136623
-
Functional and epigenetic studies reveal multistep differentiation and plasticity of in vitro-generated and in vivo-derived follicular T helper cells
-
Lu K.T., et al. Functional and epigenetic studies reveal multistep differentiation and plasticity of in vitro-generated and in vivo-derived follicular T helper cells. Immunity 2011, 35:622-632.
-
(2011)
Immunity
, vol.35
, pp. 622-632
-
-
Lu, K.T.1
-
228
-
-
84255178198
-
Early Th1 cell differentiation is marked by a Tfh cell-like transition
-
Nakayamada S., et al. Early Th1 cell differentiation is marked by a Tfh cell-like transition. Immunity 2011, 35:919-931.
-
(2011)
Immunity
, vol.35
, pp. 919-931
-
-
Nakayamada, S.1
-
229
-
-
84859897308
-
The development and fate of follicular helper T cells defined by an IL-21 reporter mouse
-
Luthje K., et al. The development and fate of follicular helper T cells defined by an IL-21 reporter mouse. Nat Immunol 2012, 13:491-498.
-
(2012)
Nat Immunol
, vol.13
, pp. 491-498
-
-
Luthje, K.1
-
230
-
-
75749122181
-
Innate production of T(H)2 cytokines by adipose tissue-associated c-Kit(+)Sca-1(+) lymphoid cells
-
Moro K., et al. Innate production of T(H)2 cytokines by adipose tissue-associated c-Kit(+)Sca-1(+) lymphoid cells. Nature 2010, 463:540-544.
-
(2010)
Nature
, vol.463
, pp. 540-544
-
-
Moro, K.1
-
231
-
-
77951817855
-
Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity
-
Neill D.R., et al. Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity. Nature 2010, 464:1367-1370.
-
(2010)
Nature
, vol.464
, pp. 1367-1370
-
-
Neill, D.R.1
-
232
-
-
77954926597
-
Systemically dispersed innate IL-13-expressing cells in type 2 immunity
-
Price A.E., et al. Systemically dispersed innate IL-13-expressing cells in type 2 immunity. Proc Natl Acad Sci USA 2010, 107:11489-11494.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 11489-11494
-
-
Price, A.E.1
-
233
-
-
33645888708
-
Identification of an interleukin (IL)-25-dependent cell population that provides IL-4, IL-5, and IL-13 at the onset of helminth expulsion
-
Fallon P.G., et al. Identification of an interleukin (IL)-25-dependent cell population that provides IL-4, IL-5, and IL-13 at the onset of helminth expulsion. J Exp Med 2006, 203:1105-1116.
-
(2006)
J Exp Med
, vol.203
, pp. 1105-1116
-
-
Fallon, P.G.1
-
234
-
-
84866519013
-
Retinoic-acid-receptor-related orphan nuclear receptor alpha is required for natural helper cell development and allergic inflammation
-
Halim T.Y., et al. Retinoic-acid-receptor-related orphan nuclear receptor alpha is required for natural helper cell development and allergic inflammation. Immunity 2012, 37:463-474.
-
(2012)
Immunity
, vol.37
, pp. 463-474
-
-
Halim, T.Y.1
-
235
-
-
84863393407
-
Transcription factor RORalpha is critical for nuocyte development
-
Wong S.H., et al. Transcription factor RORalpha is critical for nuocyte development. Nat Immunol 2012, 13:229-236.
-
(2012)
Nat Immunol
, vol.13
, pp. 229-236
-
-
Wong, S.H.1
-
236
-
-
84867769688
-
The transcription factor GATA-3 controls cell fate and maintenance of type 2 innate lymphoid cells
-
Hoyler T., et al. The transcription factor GATA-3 controls cell fate and maintenance of type 2 innate lymphoid cells. Immunity 2012, 37:634-648.
-
(2012)
Immunity
, vol.37
, pp. 634-648
-
-
Hoyler, T.1
-
237
-
-
84867773093
-
The transcription factor GATA3 is essential for the function of human type 2 innate lymphoid cells
-
Mjosberg J., et al. The transcription factor GATA3 is essential for the function of human type 2 innate lymphoid cells. Immunity 2012, 37:649-659.
-
(2012)
Immunity
, vol.37
, pp. 649-659
-
-
Mjosberg, J.1
-
238
-
-
84879311467
-
Essential, dose-dependent role for the transcription factor Gata3 in the development of IL-5+ and IL-13+ type 2 innate lymphoid cells
-
Klein Wolterink R.G., et al. Essential, dose-dependent role for the transcription factor Gata3 in the development of IL-5+ and IL-13+ type 2 innate lymphoid cells. Proc Natl Acad Sci USA 2013, 110:10240-10245.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 10240-10245
-
-
Klein Wolterink, R.G.1
-
239
-
-
84876762753
-
T cell factor 1 is required for group 2 innate lymphoid cell generation
-
Yang Q., et al. T cell factor 1 is required for group 2 innate lymphoid cell generation. Immunity 2013, 38:694-704.
-
(2013)
Immunity
, vol.38
, pp. 694-704
-
-
Yang, Q.1
-
240
-
-
84881464799
-
Critical role of p38 and GATA3 in natural helper cell function
-
Furusawa J., et al. Critical role of p38 and GATA3 in natural helper cell function. J Immunol 2013, 191:1818-1826.
-
(2013)
J Immunol
, vol.191
, pp. 1818-1826
-
-
Furusawa, J.1
-
241
-
-
84888000653
-
Specification of type 2 innate lymphocytes by the transcriptional determinant Gfi1
-
Spooner C.J., et al. Specification of type 2 innate lymphocytes by the transcriptional determinant Gfi1. Nat Immunol 2013, 14:1229-1236.
-
(2013)
Nat Immunol
, vol.14
, pp. 1229-1236
-
-
Spooner, C.J.1
-
242
-
-
79959380307
-
Innate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunity
-
Chang Y.J., et al. Innate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunity. Nat Immunol 2011, 12:631-638.
-
(2011)
Nat Immunol
, vol.12
, pp. 631-638
-
-
Chang, Y.J.1
-
243
-
-
84858775590
-
Lung natural helper cells are a critical source of Th2 cell-type cytokines in protease allergen-induced airway inflammation
-
Halim T.Y., Krauss R.H., Sun A.C., Takei F. Lung natural helper cells are a critical source of Th2 cell-type cytokines in protease allergen-induced airway inflammation. Immunity 2012, 36:451-463.
-
(2012)
Immunity
, vol.36
, pp. 451-463
-
-
Halim, T.Y.1
Krauss, R.H.2
Sun, A.C.3
Takei, F.4
-
244
-
-
85027948313
-
Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus
-
Monticelli L.A., et al. Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus. Nat Immunol 2011, 12:1045-1054.
-
(2011)
Nat Immunol
, vol.12
, pp. 1045-1054
-
-
Monticelli, L.A.1
-
245
-
-
84907195502
-
Basophils promote innate lymphoid cell responses in inflamed skin
-
Kim B.S., et al. Basophils promote innate lymphoid cell responses in inflamed skin. J Immunol 2014, 193:3717-3725.
-
(2014)
J Immunol
, vol.193
, pp. 3717-3725
-
-
Kim, B.S.1
-
246
-
-
84878257969
-
Cutaneous immunosurveillance and regulation of inflammation by group 2 innate lymphoid cells
-
Roediger B., et al. Cutaneous immunosurveillance and regulation of inflammation by group 2 innate lymphoid cells. Nat Immunol 2013, 14:564-573.
-
(2013)
Nat Immunol
, vol.14
, pp. 564-573
-
-
Roediger, B.1
-
247
-
-
84925486777
-
Group 2 innate lymphoid cells promote beginning of white adipose tissue and limit obesity
-
Brestoff J.R., et al. Group 2 innate lymphoid cells promote beginning of white adipose tissue and limit obesity. Nature 2014.
-
(2014)
Nature
-
-
Brestoff, J.R.1
-
248
-
-
84920940721
-
Activated type 2 innate lymphoid cells regulate beige fat biogenesis
-
Lee M.W., et al. Activated type 2 innate lymphoid cells regulate beige fat biogenesis. Cell 2015, 160:74-87.
-
(2015)
Cell
, vol.160
, pp. 74-87
-
-
Lee, M.W.1
-
249
-
-
80054927155
-
An IL-9 fate reporter demonstrates the induction of an innate IL-9 response in lung inflammation
-
Wilhelm C., et al. An IL-9 fate reporter demonstrates the induction of an innate IL-9 response in lung inflammation. Nat Immunol 2011, 12:1071-1077.
-
(2011)
Nat Immunol
, vol.12
, pp. 1071-1077
-
-
Wilhelm, C.1
-
250
-
-
84890852091
-
IL-9-mediated survival of type 2 innate lymphoid cells promotes damage control in helminth-induced lung inflammation
-
Turner J.E., et al. IL-9-mediated survival of type 2 innate lymphoid cells promotes damage control in helminth-induced lung inflammation. J Exp Med 2013, 210:2951-2965.
-
(2013)
J Exp Med
, vol.210
, pp. 2951-2965
-
-
Turner, J.E.1
-
252
-
-
84882778526
-
Lung type 2 innate lymphoid cells express cysteinyl leukotriene receptor 1, which regulates TH2 cytokine production
-
Doherty T.A., et al. Lung type 2 innate lymphoid cells express cysteinyl leukotriene receptor 1, which regulates TH2 cytokine production. J Allergy Clin Immunol 2013, 132:205-213.
-
(2013)
J Allergy Clin Immunol
, vol.132
, pp. 205-213
-
-
Doherty, T.A.1
-
253
-
-
84897402119
-
Prostaglandin D2 activates group 2 innate lymphoid cells through chemoattractant receptor-homologous molecule expressed on TH2 cells
-
Xue L., et al. Prostaglandin D2 activates group 2 innate lymphoid cells through chemoattractant receptor-homologous molecule expressed on TH2 cells. J Allergy Clin Immunol 2014, 133:1184-1194.
-
(2014)
J Allergy Clin Immunol
, vol.133
, pp. 1184-1194
-
-
Xue, L.1
-
254
-
-
84900397775
-
Basophil-derived interleukin-4 controls the function of natural helper cells, a member of ILC2s, in lung inflammation
-
Motomura Y., et al. Basophil-derived interleukin-4 controls the function of natural helper cells, a member of ILC2s, in lung inflammation. Immunity 2014, 40:758-771.
-
(2014)
Immunity
, vol.40
, pp. 758-771
-
-
Motomura, Y.1
-
255
-
-
84876008998
-
Lipoxin A4 regulates natural killer cell and type 2 innate lymphoid cell activation in asthma
-
174ra126
-
Barnig C., et al. Lipoxin A4 regulates natural killer cell and type 2 innate lymphoid cell activation in asthma. Sci Trans Med 2013, 5:174ra126.
-
(2013)
Sci Trans Med
, vol.5
-
-
Barnig, C.1
-
256
-
-
84890825282
-
A role for IL-25 and IL-33-driven type-2 innate lymphoid cells in atopic dermatitis
-
Salimi M., et al. A role for IL-25 and IL-33-driven type-2 innate lymphoid cells in atopic dermatitis. J Exp Med 2013, 210:2939-2950.
-
(2013)
J Exp Med
, vol.210
, pp. 2939-2950
-
-
Salimi, M.1
-
257
-
-
84907370454
-
MHCII-mediated dialog between group 2 innate lymphoid cells and CD4(+) T cells potentiates type 2 immunity and promotes parasitic helminth expulsion
-
Oliphant C.J., et al. MHCII-mediated dialog between group 2 innate lymphoid cells and CD4(+) T cells potentiates type 2 immunity and promotes parasitic helminth expulsion. Immunity 2014, 41:283-295.
-
(2014)
Immunity
, vol.41
, pp. 283-295
-
-
Oliphant, C.J.1
-
258
-
-
84894736115
-
Type 2 innate lymphoid cells drive CD4+ Th2 cell responses
-
Mirchandani A.S., et al. Type 2 innate lymphoid cells drive CD4+ Th2 cell responses. J Immunol 2014, 192:2442-2448.
-
(2014)
J Immunol
, vol.192
, pp. 2442-2448
-
-
Mirchandani, A.S.1
-
259
-
-
84907953760
-
Group 2 innate lymphoid cells and CD4+ T cells cooperate to mediate type 2 immune response in mice
-
Drake L.Y., Iijima K., Kita H. Group 2 innate lymphoid cells and CD4+ T cells cooperate to mediate type 2 immune response in mice. Allergy 2014, 69:1300-1307.
-
(2014)
Allergy
, vol.69
, pp. 1300-1307
-
-
Drake, L.Y.1
Iijima, K.2
Kita, H.3
-
260
-
-
84896343916
-
Group 2 innate lymphoid cells are critical for the initiation of adaptive T helper 2 cell-mediated allergic lung inflammation
-
Halim T.Y., et al. Group 2 innate lymphoid cells are critical for the initiation of adaptive T helper 2 cell-mediated allergic lung inflammation. Immunity 2014, 40:425-435.
-
(2014)
Immunity
, vol.40
, pp. 425-435
-
-
Halim, T.Y.1
-
261
-
-
84915745730
-
Interleukin-5-producing group 2 innate lymphoid cells control eosinophilia induced by interleukin-2 therapy
-
Van Gool F., et al. Interleukin-5-producing group 2 innate lymphoid cells control eosinophilia induced by interleukin-2 therapy. Blood 2014, 124:3572-3576.
-
(2014)
Blood
, vol.124
, pp. 3572-3576
-
-
Van Gool, F.1
-
262
-
-
18244405108
-
IL-25 induces IL-4, IL-5, and IL-13 and Th2-associated pathologies in vivo
-
Fort M.M., et al. IL-25 induces IL-4, IL-5, and IL-13 and Th2-associated pathologies in vivo. Immunity 2001, 15:985-995.
-
(2001)
Immunity
, vol.15
, pp. 985-995
-
-
Fort, M.M.1
-
263
-
-
27744446058
-
IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines
-
Schmitz J., et al. IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines. Immunity 2005, 23:479-490.
-
(2005)
Immunity
, vol.23
, pp. 479-490
-
-
Schmitz, J.1
-
264
-
-
77950261975
-
How are T(H)2-type immune responses initiated and amplified?
-
Paul W.E., Zhu J. How are T(H)2-type immune responses initiated and amplified?. Nat Rev Immunol 2010, 10:225-235.
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 225-235
-
-
Paul, W.E.1
Zhu, J.2
|