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Volumn 3, Issue , 2012, Pages

T-bet and GATA3 orchestrate Th1 and Th2 differentiation through lineage-specific targeting of distal regulatory elements

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR T BET;

EID: 84871783406     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms2260     Document Type: Article
Times cited : (268)

References (51)
  • 1
    • 77952313777 scopus 로고    scopus 로고
    • Differentiation of effector CD4 T cell populations
    • Zhu, J., Yamane, H. & Paul, W. E. Differentiation of effector CD4 T cell populations. Annu. Rev. Immunol. 28, 445-489 (2010).
    • (2010) Annu. Rev. Immunol. , vol.28 , pp. 445-489
    • Zhu, J.1    Yamane, H.2    Paul, W.E.3
  • 4
    • 26444452042 scopus 로고    scopus 로고
    • T-bet is required for protection against vaccinia virus infection
    • DOI 10.1128/JVI.79.20.12798-12806.2005
    • Matsui, M., Moriya, O., Yoshimoto, T. & Akatsuka, T. T-bet is required for protection against vaccinia virus infection. J. Virol. 79, 12798-12806 (2005). (Pubitemid 41433199)
    • (2005) Journal of Virology , vol.79 , Issue.20 , pp. 12798-12806
    • Matsui, M.1    Moriya, O.2    Yoshimoto, T.3    Akatsuka, T.4
  • 7
    • 0030764961 scopus 로고    scopus 로고
    • Transcription factor GATA-3 is differentially expressed in murine Th1 and Th2 cells and controls Th2-specific expression of the interleukin-5 gene
    • Zhang, D. H. et al. Transcription factor GATA-3 is differentially expressed in murine Th1 and Th2 cells and controls Th2-specific expression of the interleukin-5 gene. J. Biol. Chem. 272, 21597-21603 (1997).
    • (1997) J. Biol. Chem. , vol.272 , pp. 21597-21603
    • Zhang, D.H.1
  • 10
    • 58849092225 scopus 로고    scopus 로고
    • Epigenetic control of T-helper-cell differentiation
    • Wilson, C. B., Rowell, E. & Sekimata, M. Epigenetic control of T-helper-cell differentiation. Nat. Rev. Immunol. 9, 91-105 (2009).
    • (2009) Nat. Rev. Immunol. , vol.9 , pp. 91-105
    • Wilson, C.B.1    Rowell, E.2    Sekimata, M.3
  • 11
    • 70449571945 scopus 로고    scopus 로고
    • The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes
    • Jenner, R. G. et al. The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes. Proc. Natl. Acad. Sci. USA 106, 17876-17881 (2009).
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 17876-17881
    • Jenner, R.G.1
  • 12
    • 33846489173 scopus 로고    scopus 로고
    • Erratum: Transcription factors T-bet and Runx3 cooperate to activate Ifng and silence Il4 in T helper type 1 cells (Nature Immunology)
    • DOI 10.1038/ni1424, PII NI1424
    • Djuretic, I. M. et al. Transcription factors T-bet and Runx3 cooperate to activate Ifng and silence Il4 in T helper type 1 cells. Nat. Immunol. 8, 145-153 (2007). (Pubitemid 46152645)
    • (2007) Nature Immunology , vol.8 , Issue.2 , pp. 145-153
    • Djuretic, I.M.1    Levanon, D.2    Negreanu, V.3    Groner, Y.4    Rao, A.5    Ansel, K.M.6
  • 14
    • 1042278131 scopus 로고    scopus 로고
    • A Distal Enhancer in the Interferon-γ (IFN-γ) Locus Revealed by Genome Sequence Comparison
    • DOI 10.1074/jbc.M307904200
    • Lee, D. U., Avni, O., Chen, L. & Rao, A. A distal enhancer in the interferongamma (IFN-gamma) locus revealed by genome sequence comparison. J. Biol. Chem. 279, 4802-4810 (2004). (Pubitemid 38199075)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.6 , pp. 4802-4810
    • Lee, D.U.1    Avni, O.2    Chen, L.3    Rao, A.4
  • 17
    • 67650997080 scopus 로고    scopus 로고
    • Cohesins form chromosomal cis-interactions at the developmentally regulated IFNG locus
    • Hadjur, S. et al. Cohesins form chromosomal cis-interactions at the developmentally regulated IFNG locus. Nature 460, 410-413 (2009).
    • (2009) Nature , vol.460 , pp. 410-413
    • Hadjur, S.1
  • 18
    • 70349756895 scopus 로고    scopus 로고
    • CCCTC-binding factor and the transcription factor T-bet orchestrate T helper 1 cell-specific structure and function at the interferongamma locus
    • Sekimata, M. et al. CCCTC-binding factor and the transcription factor T-bet orchestrate T helper 1 cell-specific structure and function at the interferongamma locus. Immunity 31, 551-564 (2009).
    • (2009) Immunity , vol.31 , pp. 551-564
    • Sekimata, M.1
  • 19
    • 0035041537 scopus 로고    scopus 로고
    • Regulation of IL-4 gene expression by distal regulatory elements and GATA-3 at the chromatin level
    • DOI 10.1016/S1074-7613(01)00125-X
    • Lee, G. R., Fields, P. E. & Flavell, R. A. Regulation of IL-4 gene expression by distal regulatory elements and GATA-3 at the chromatin level. Immunity 14, 447-459 (2001). (Pubitemid 32441597)
    • (2001) Immunity , vol.14 , Issue.4 , pp. 447-459
    • Lee, G.R.1    Fields, P.E.2    Flavell, R.A.3
  • 20
    • 0035887640 scopus 로고    scopus 로고
    • The cell type-specific expression of the murine IL-13 gene is regulated by GATA-3
    • Kishikawa, H. et al. The cell type-specific expression of the murine IL-13 gene is regulated by GATA-3. J. Immunol. 167, 4414-4420 (2001). (Pubitemid 32954318)
    • (2001) Journal of Immunology , vol.167 , Issue.8 , pp. 4414-4420
    • Kishikawa, H.1    Sun, J.2    Choi, A.3    Miaw, S.4    Ho, I.-C.5
  • 21
    • 5444237577 scopus 로고    scopus 로고
    • Long-range intrachromosomal interactions in the T helper type 2 cytokine locus
    • DOI 10.1038/ni1115
    • Spilianakis, C. G. & Flavell, R. A. Long-range intrachromosomal interactions in the T helper type 2 cytokine locus. Nat. Immunol. 5, 1017-1027 (2004). (Pubitemid 41057721)
    • (2004) Nature Immunology , vol.5 , Issue.10 , pp. 1017-1027
    • Spilianakis, C.G.1    Flavell, R.A.2
  • 22
    • 23344453342 scopus 로고    scopus 로고
    • A critical control element for interleukin-4 memory expression in T helper lymphocytes
    • Tykocinski, L. O. et al. A critical control element for interleukin-4 memory expression in T helper lymphocytes. J. Biol. Chem. 280, 28177-28185 (2005).
    • (2005) J. Biol. Chem. , vol.280 , pp. 28177-28185
    • Tykocinski, L.O.1
  • 24
    • 0032531605 scopus 로고    scopus 로고
    • Cutting edge: Differential responsiveness of the IL-5 and IL-4 genes to transcription factor GATA-3
    • Zhang, D. H., Yang, L. & Ray, A. Differential responsiveness of the IL-5 and IL-4 genes to transcription factor GATA-3. J. Immunol. 161, 3817-3821 (1998). (Pubitemid 28468953)
    • (1998) Journal of Immunology , vol.161 , Issue.8 , pp. 3817-3821
    • Zhang, D.-H.1    Yang, L.2    Ray, A.3
  • 25
    • 33750465872 scopus 로고    scopus 로고
    • SATB1 packages densely looped, transcriptionally active chromatin for coordinated expression of cytokine genes
    • DOI 10.1038/ng1913, PII NG1913
    • Cai, S., Lee, C. C. & Kohwi-Shigematsu, T. SATB1 packages densely looped, transcriptionally active chromatin for coordinated expression of cytokine genes. Nat. Genet. 38, 1278-1288 (2006). (Pubitemid 44646290)
    • (2006) Nature Genetics , vol.38 , Issue.11 , pp. 1278-1288
    • Cai, S.1    Lee, C.C.2    Kohwi-Shigematsu, T.3
  • 27
    • 34250762587 scopus 로고    scopus 로고
    • Dynamic changes in histone-methylation 'marks' across the locus encoding interferon-γ during the differentiation of T helper type 2 cells
    • DOI 10.1038/ni1473, PII NI1473
    • Chang, S. & Aune, T. M. Dynamic changes in histone-methylation 'marks' across the locus encoding interferon-gamma during the differentiation of T helper type 2 cells. Nat. Immunol. 8, 723-731 (2007). (Pubitemid 46965348)
    • (2007) Nature Immunology , vol.8 , Issue.7 , pp. 723-731
    • Chang, S.1    Aune, T.M.2
  • 28
    • 12344269852 scopus 로고    scopus 로고
    • T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3
    • DOI 10.1126/science.1103336
    • Hwang, E. S., Szabo, S. J., Schwartzberg, P. L. & Glimcher, L. H. T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3. Science 307, 430-433 (2005). (Pubitemid 40139989)
    • (2005) Science , vol.307 , Issue.5708 , pp. 430-433
    • Hwang, E.S.1    Szabo, S.J.2    Schwartzberg, P.L.3    Glimcher, L.H.4
  • 29
    • 0036721797 scopus 로고    scopus 로고
    • Cytokine coexpression during human Th1/Th2 cell differentiation: Direct evidence for coordinated expression of Th2 cytokines
    • Cousins, D. J., Lee, T. H. & Staynov, D. Z. Cytokine coexpression during human Th1/Th2 cell differentiation: direct evidence for coordinated expression of Th2 cytokines. J. Immunol. 169, 2498-2506 (2002). (Pubitemid 34920994)
    • (2002) Journal of Immunology , vol.169 , Issue.5 , pp. 2498-2506
    • Cousins, D.J.1    Lee, T.H.2    Staynov, D.Z.3
  • 30
    • 34248349587 scopus 로고    scopus 로고
    • GATA3 up-regulation associated with surface expression of CD294/CRTH2: A unique feature of human Th cells
    • DOI 10.1182/blood-2006-05-025940
    • De Fanis, U. et al. GATA3 up-regulation associated with surface expression of CD294/CRTH2: a unique feature of human Th cells. Blood 109, 4343-4350 (2007). (Pubitemid 46743402)
    • (2007) Blood , vol.109 , Issue.10 , pp. 4343-4350
    • De Fanis, U.1    Mori, F.2    Kurnat, R.J.3    Won, K.L.4    Bova, M.5    Adkinson, N.F.6    Casolaro, V.7
  • 32
    • 74549179138 scopus 로고    scopus 로고
    • Interferons direct Th2 cell reprogramming to generate a stable GATA-3(+)T-bet(+) cell subset with combined Th2 and Th1 cell functions
    • Hegazy, A. N. et al. Interferons direct Th2 cell reprogramming to generate a stable GATA-3(+)T-bet(+) cell subset with combined Th2 and Th1 cell functions. Immunity 32, 116-128 (2010).
    • (2010) Immunity , vol.32 , pp. 116-128
    • Hegazy, A.N.1
  • 33
    • 77649220954 scopus 로고    scopus 로고
    • Mechanisms underlying lineage commitment and plasticity of helper CD4+ T cells
    • O'Shea, J. J. & Paul, W. E. Mechanisms underlying lineage commitment and plasticity of helper CD4+ T cells. Science 327, 1098-1102 (2010).
    • (2010) Science , vol.327 , pp. 1098-1102
    • O'Shea, J.J.1    Paul, W.E.2
  • 35
    • 58049191558 scopus 로고    scopus 로고
    • Chromatin signatures in multipotent human hematopoietic stem cells indicate the fate of bivalent genes during differentiation
    • Cui, K. et al. Chromatin signatures in multipotent human hematopoietic stem cells indicate the fate of bivalent genes during differentiation. Cell Stem Cell 4, 80-93 (2009).
    • (2009) Cell Stem Cell , vol.4 , pp. 80-93
    • Cui, K.1
  • 36
    • 53849146020 scopus 로고    scopus 로고
    • Model-based analysis of ChIP-Seq (MACS)
    • Zhang, Y. et al. Model-based analysis of ChIP-Seq (MACS). Genome Biol. 9, R137 (2008).
    • (2008) Genome Biol. , vol.9
    • Zhang, Y.1
  • 38
    • 76249125198 scopus 로고    scopus 로고
    • Integration of distinct intracellular signaling pathways at distal regulatory elements directs T-bet expression in human CD4+ T cells
    • Placek, K. et al. Integration of distinct intracellular signaling pathways at distal regulatory elements directs T-bet expression in human CD4+ T cells. J. Immunol. 183, 7743-7751 (2009).
    • (2009) J. Immunol. , vol.183 , pp. 7743-7751
    • Placek, K.1
  • 40
    • 79958042030 scopus 로고    scopus 로고
    • Genome-wide analysis reveals unique regulation of transcription of Th2-specific genes by GATA3
    • Horiuchi, S. et al. Genome-wide analysis reveals unique regulation of transcription of Th2-specific genes by GATA3. J. Immunol. 186, 6378-6389 (2011).
    • (2011) J. Immunol. , vol.186 , pp. 6378-6389
    • Horiuchi, S.1
  • 41
    • 80051885764 scopus 로고    scopus 로고
    • Genome-wide analyses of transcription factor GATA3-mediated gene regulation in distinct T cell types
    • Wei, G. et al. Genome-wide analyses of transcription factor GATA3-mediated gene regulation in distinct T cell types. Immunity 35, 299-311 (2011).
    • (2011) Immunity , vol.35 , pp. 299-311
    • Wei, G.1
  • 42
    • 0037722938 scopus 로고    scopus 로고
    • Program-specific distribution of a transcription factor dependent on partner transcription factor and MAPK signaling
    • DOI 10.1016/S0092-8674(03)00301-5
    • Zeitlinger, J. et al. Program-specific distribution of a transcription factor dependent on partner transcription factor and MAPK signaling. Cell 113, 395-404 (2003). (Pubitemid 36556120)
    • (2003) Cell , vol.113 , Issue.3 , pp. 395-404
    • Zeitlinger, J.1    Simon, I.2    Harbison, C.T.3    Hannett, N.M.4    Volkert, T.L.5    Fink, G.R.6    Young, R.A.7
  • 43
    • 65749103365 scopus 로고    scopus 로고
    • The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation
    • Koch, M. A. et al. The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation. Nat. Immunol. 10, 595-602 (2009).
    • (2009) Nat. Immunol. , vol.10 , pp. 595-602
    • Koch, M.A.1
  • 44
    • 70449532980 scopus 로고    scopus 로고
    • Decrease of Foxp3+ Treg cell number and acquisition of effector cell phenotype during lethal infection
    • Oldenhove, G. et al. Decrease of Foxp3+ Treg cell number and acquisition of effector cell phenotype during lethal infection. Immunity 31, 772-786 (2009).
    • (2009) Immunity , vol.31 , pp. 772-786
    • Oldenhove, G.1
  • 45
    • 9244223651 scopus 로고    scopus 로고
    • Induction of T helper type 1-like regulatory cells that express Foxp3 and protect against airway hyper-reactivity
    • DOI 10.1038/ni1122
    • Stock, P. et al. Induction of T helper type 1-like regulatory cells that express Foxp3 and protect against airway hyper-reactivity. Nat. Immunol. 5, 1149-1156 (2004). (Pubitemid 39549629)
    • (2004) Nature Immunology , vol.5 , Issue.11 , pp. 1149-1156
    • Stock, P.1    Akbari, O.2    Berry, G.3    Freeman, G.J.4    DeKruyff, R.H.5    Umetsu, D.T.6
  • 47
    • 34047258309 scopus 로고    scopus 로고
    • Positive-Feedback Loops as a Flexible Biological Module
    • DOI 10.1016/j.cub.2007.03.016, PII S0960982207011177
    • Ingolia, N. T. & Murray, A. W. Positive-feedback loops as a flexible biological module. Curr. Biol. 17, 668-677 (2007). (Pubitemid 46552252)
    • (2007) Current Biology , vol.17 , Issue.8 , pp. 668-677
    • Ingolia, N.T.1    Murray, A.W.2
  • 49
    • 76749133610 scopus 로고    scopus 로고
    • Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate
    • Zheng, Y. et al. Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate. Nature 463, 808-812 (2010).
    • (2010) Nature , vol.463 , pp. 808-812
    • Zheng, Y.1
  • 50
    • 0034677646 scopus 로고    scopus 로고
    • A novel transcription factor, T-bet, directs Th1 lineage commitment
    • Szabo, S. J. et al. A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell 100, 655-669 (2000).
    • (2000) Cell , vol.100 , pp. 655-669
    • Szabo, S.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.