OX40 costimulation enhances interleukin-4 (IL-4) expression at priming and promotes the differentiation of naive human CD4+ T cells into high IL- 4-producing effectors

Blood

Volumn 92, Issue 9, 1998, Pages 3338-3345

  Ohshima, Yusei ^b   Yang, Liang Peng ^b   Uchiyama, Takashki ^b   Tanaka, Yuetsu ^b   Baum, Peter ^b   Sergerie, Martin ^b   Hermann, Patrice ^b   Delespesse, Guy ^a  

^a NOTRE DAME HOSPITAL   (Canada)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; INTERLEUKIN 4; TUMOR NECROSIS FACTOR RECEPTOR;

ARTICLE; CELL DIFFERENTIATION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOREGULATION; IMMUNOSTIMULATION; LYMPHOCYTE ACTIVATION; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION;

EID: 0032213337     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v92.9.3338.421k19_3338_3345     Document Type: Article

References (50)

1. Seder R, Paul WE: Acquisition of lymphokine-producing phenotype by CD4+ T cells. Annu Rev Immunol 12:635, 1994
2. O'Garra A, Murphy K: Role of cytokines in development of Th l and Th 2 cells. Chem Immunol 63:1, 1996
3. Constant SL, Bottomly K: Induction of Thl and Th2 CD4+ T cell responses: The alternative approaches. Annu Rev Immunol 15:297, 1997
4. + T cells. J Immunol 158:1085, 1997
5. Constant S, Pfeiffer C, Woodard A, Pasqualini T, Bottomly K: Extent of T cell receptor ligation can determine the functional differentiation of naive CD4+ T cells. J Exp Med 182:1591, 1995
6. Hosken NA, Shibuya K, Heath AW, Murphy KM, O'Garra A: The effect of antigen dose on CD4+ T helper cell phenotype development in a T cell receptor-aβ-transgenie model. J Exp Med 182:1579, 1995
7. Pfeiffer C, Stein J, Southwood S, Ketelaar H, Sette A, Bottomly K: Altered peptide ligands can control CD4 T lymphocyte differentiation in vivo. J Exp Med 181:1569, 1995
8. Tao X, Constant S, Jorritsma P, Bottomly K: Strength of TCR signal determines the costimulatory requirements for Thl and Th2 CD4+ T cell differentiation. J Immunol 159:5956, 1997
9. Cause WC, Halvorson MJ, Lu P, Greenwald R, Linsley P, Urban JF, Finkelman FD: The function of costimulatory molecules and the development of IL-4-producing T cells. Immunol Today 18:115, 1997
10. Del Prete G, De Carli M, D'Elios MM, Daniel KC, Almerigogna F, Alderson M, Smith CA, Thomas E, Romagnani S: CD30-mediated signaling promotes the development of human T helper type 2-like T cells, J Exp Med 182:1655, 1995
11. Stüber E, Strober W, Neurath M: Blocking the CD40L-CD40 interaction in vivo specifically prevents the priming of T helper 1 cells through the inhibition of interleukin 12 secretion. J Exp Med 183:693, 1996
12. Lenschow DJ, Herold KC, Rhee L, Patel B, Koons A, Qin HY, Fuchs E, Singh B, Thompson CB, Bluestone JA: CD28/B7 regulation of Thl and Th2 subsets in the development of autoimmune diabetes. Immunity 5:285, 1996
13. Ramirez F, Fowell DJ, Puklavec M, Simmonds S, Manson D: Glucocorticoids promote a Th2 cytokine response by CD4+ T cells in vitro. J Immunol 156:2406, 1996
14. Hsieh CS, Macatonia SE, O'GarraA, Murphy KM: T cell genetic background determines default T helper phenotype development in vitro. J Exp Med 181:713, 1995
15. + T cells from T cell receptor transgenic mice. J Exp Med 176:1091, 1992
16. Hsieh CS, Macatonia SE, Tripp CS, Wolf SF, O'Garra A, Murphy KM: Development of Thl CD4+ T cells through IL-12 produced by Listeria-induced macrophages. Science 260:547, 1993
17. Ma X, D' Andrea A, Kubin M, Aste-Amezaga M, Sartori A, Monteiro J, Showe L, Wysocka M, Trinchieri G: Production of interleukin-12. Res Immunol 146:432, 1996
18. Macatonia SE, Hosken NA, Litton M, Vieira P, Hsieh CS, Culpepper JA, Wysocka M, Trinchieri G, Murphy KM, O' Garra A: Dendritic cells produce IL-12 and direct the development of Thl cells from naive CD4+T cells. J Immunol 154:5071, 1995
19. Ohshima Y, Delespesse G: T cell-derived IL-4 and dendritic cell-derived IL-12 regulate the lymphokine-producing phenotype of al loan tige n-primed naive human CD4 T cells. J Immunol 158:629, 1997
20. Noben-Trauth N, Shultz LD, Brombacher F, Urban JF Jr, Gu H, Paul WE: An interleukin 4 (IL-4)-independent pathway for CD4+ T cell IL-4 production is revealed in IL-4 receptor-deficient mice. Proc Natl Acad Sci USA 94:10838, 1997
21. pos T cells promptly produce interleukin 4 in response to in vivo challenge with anti-CD3. J Exp Med 179:1285, 1994
22. Ferrick DA, Schrenzel MD, Mulvania T, Hsieh B, Ferlin WG, Lepper H: Differential production of interferon-γ and imerleukin-4 in response to Thl- and Th2-stimulating pathogens by γδ T cells m vivo. Nature 373:255, 1995
23. Seder RA, Paul WE, Dvorak AM, Sharkis SJ, Kagey-Sobotka A, Niv Y, Finkelman FD, Barbieri SA, Galli SJ. Plaut M: Mouse splenic and bone marrow cell populations that express high-affinity FcE receptors and produce interleukin 4 are highly enriched in basophils. Proc Natl Acad Sci USA 88:2835, 1991
24. + T cells into IL-4-secreting cells, J Immunol 152:5180, 1994
25. Rincon M, Anguita J, Nakamura T, Fikrig E, Flavell RA: Interleukin (IL)-6 directs the differentiation of IL-4-producing CD4+ T cells. J Exp Med 185:461, 1997
26. Croft M, Swain SL: Recently activated naive CD4 T cells can help resting B cells, and can produce sufficient autocrine IL-4 to drive differentiation to secretion of T helper 2-type cytokines. J Immunol 154:4269, 1995
27. Yang LP, Byun DG, Demeure CE, Vezzio N, Delespesse G: Default development of cloned human naive CD4 T cells into interleukin-4-and interleukin-5-producing effector cells. Eur J Immunol 25:3517, 1995
28. Demeure CE, Yang LP, Byun DG, Ishihara I, Vezzio N, Delespesse G: Human naive CD4 T cells produce interleukin-4 at priming and acquire a Th2 phenotype upon repetitive stimulations in neutral conditions. Eur J Immunol 25:2722, 1995
29. Yang LP, Demeure CE, Byun DG, Vezzio N, Delespesse G: Maturation of neonatal human CD4 T cells: III. Role of B7 costimulation at priming. Int Immunol 7:1987, 1995
30. Rulifson IC, Sperling AI, Fields PE, Fitch FW, Bluestone JA: CD28 promotes the production of Th2 cytokines. J Immunol 158:658, 1997
31. Mallett S, Fossum S, Barclay AN: Characterization of the MRC OX40 antigen of activated CD4 positive T lymphocytes-A molecule related to nerve growth factor receptor. EMBO J 9:1063, 1990
32. Imura A, Hori T, Imada K, Ishikawa T, Tanaka Y, Maeda M, Imamura S, Uchiyama T: The human OX40/gp34 system directly mediates adhesion of activated T cells to vascular endothelical cells. J Exp Med 183:2185, 1996
33. Tozawa H, Andoh S, Takayama Y, Tanaka Y, Lee B, Nakamura H, Hayami M, Hinuma Y: Species-dependent antigenicity of the 34-kDa glycoprotein found on the membrane of various primate lymphocytes transformed by human T-cell leukemia virus type-I (HTLV-I) and simian T-cell leukemia virus (STLV-I). Int J Cancer 41:231, 1988
34. Baum PR, Gayle RB III, Ramsdell F, Srinivasan S, Sorensen RA, Watson ML, Seldin MF, Baker E, Sutherland GR, Clifford KM, Alderson MR, Goodwin RG, Fanslow WC: Molecular characterization of murine and human OX40/OX40 ligand systems: Identification of a human OX40 ligand as the HTLV-1-regulated protein gp34. EMBO J 13:3992, 1994
35. Azuma M, Cayabyab M, Phillips JH, Lanier L: Requirements for CD28-dependent T cell-mediated cytotoxicity. J Immunol 150:2091, 1993
36. Ohshima Y, Tanaka Y, Tozawa H, Takahashi Y, Maliszewski C, Delespesse G: Expression and function of OX40 ligand on human dendritic cells. J Immunol 159:3838, 1997
37. Lederer JA, Perez VL, DesRoches L, Kim SM, Abbas AK, Lichtman AH: Cytokine transcriptional events during helper T cell subset differentiation. J Exp Med 184:379, 1996
38. + T cells to enhance priming for interferon γ production and diminishes interleukin 4 inhibition of such priming. Proc Natl Acad Sci USA 90:10188, 1993
39. Huang H, Hu-Li J, Chen H, Ben-Sasson SZ, Paul WE: IL-4 and IL-13 production in differentiated T helper type 2 cells is not IL-4 dependent. J Tmmunol 159:3731, 1997
40. Davydov IV, Krammer PH, Li-Weber M: Nuclear factor-IL-6 activates the human IL-4 promoter in T cells. J Immunol 155:5273, 1995
41. Li-Weber M, Salgame P, Hu C, Davydov IV, Krammer PH: Differential interaction of nuclear factors with the PRE-I enhancer element of the human IL-4 promoter in different T cell subsets. J Immunol 158:1194, 1997
42. Godfrey WR, Fagnoni FF, Harara MA, Buck D, Engleman EG: Identification of a human OX-40 ligand, a costimulator of CD4+ T cells with homology to tumor necrosis factor. J Exp Med 180:757, 1994
43. Stüber E, Neurath M, Calderhead D, Fell HP, Strober W: Cross-linking of OX40 ligand, a member of the TNF/NGF cytokine family, induces proliferation and differentiation in murine splenic B cells. Immunity 2:507, 1995
44. Miner K, Croft M: Generation, persistence, and modulation of Th0 effector cells: Role of autocrine IL-4 and IFN-γ. J Immunol 160:5280, 1998
45. Arch RH, Thompson CB: 4-1BB and OX40 are members of a tumor necrosis factor (TNF)-nerve growth factor receptor subfamily that bind TNF receptor-associated factors and activate nuclear factor kappaB. Mol Cell Biol 18:558, 1998
46. Akira S, Kishimoto T: NF-IL6 and NF-κB in cytokine gene regulation. Adv Immunol 65:1, 1997
47. Van Kooten C, Rensink I, Pascual-Salcedo D, van Oers R, Aarden L: Monokine production by human T cells; IL-la production restricted memory T cells. J Immunol 146:2654, 1991
48. Banchereau J, Steinman RM: Dendritic cells and the control of immunity. Nature 392:245, 1998
49. Reis e Sousa C, Hieny S, Scharton-Kersten T, Jankovic D, Charest H, Germain RN, Sher A: In vivo microbial stimulation induces rapid CD40 ligand-independent production of interleukin 12 by dendritic cells and their redistribution to T cell areas. J Exp Med 186:1819, 1997
50. Kim YJ, Kim SH, Mantel P, Kwon BS: Human 4-1BB regulates CD28 co-stimulation to promote Thl cell responses. Eur J Immunol 28:881, 1998