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Volumn 10, Issue 7, 2009, Pages 713-720

Basophils function as antigen-presenting cells for an allergen-induced T helper type 2 response

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; ENHANCED GREEN FLUORESCENT PROTEIN; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PAPAIN;

EID: 67649216604     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.1738     Document Type: Article
Times cited : (509)

References (53)
  • 1
    • 52649167708 scopus 로고    scopus 로고
    • Zhu, J. & Paul, W.E. CD4 T cells: Fates, functions, and faults. Blood 112, 1557-1569 (2008).
    • Zhu, J. & Paul, W.E. CD4 T cells: Fates, functions, and faults. Blood 112, 1557-1569 (2008).
  • 3
    • 33244497571 scopus 로고    scopus 로고
    • Dectin-1: A signalling non-TLR pattern-recognition receptor
    • Brown, G.D. Dectin-1: A signalling non-TLR pattern-recognition receptor. Nat. Rev. Immunol. 6, 33-43 (2006).
    • (2006) Nat. Rev. Immunol , vol.6 , pp. 33-43
    • Brown, G.D.1
  • 4
    • 34249026701 scopus 로고    scopus 로고
    • Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17
    • LeibundGut-Landmann, S. et al. Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17. Nat. Immunol. 8, 630-638 (2007).
    • (2007) Nat. Immunol , vol.8 , pp. 630-638
    • LeibundGut-Landmann, S.1
  • 5
    • 34249079176 scopus 로고    scopus 로고
    • Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells
    • Acosta-Rodriguez, E.V. et al. Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells. Nat. Immunol. 8, 639-646 (2007).
    • (2007) Nat. Immunol , vol.8 , pp. 639-646
    • Acosta-Rodriguez, E.V.1
  • 6
    • 5444262511 scopus 로고    scopus 로고
    • Toll-like receptor control of the adaptive immune responses
    • Iwasaki, A. & Medzhitov, R. Toll-like receptor control of the adaptive immune responses. Nat. Immunol. 5, 987-995 (2004).
    • (2004) Nat. Immunol , vol.5 , pp. 987-995
    • Iwasaki, A.1    Medzhitov, R.2
  • 7
    • 0034775153 scopus 로고    scopus 로고
    • Toll-like receptors control activation of adaptive immune responses
    • Schnare, M. et al. Toll-like receptors control activation of adaptive immune responses. Nat. Immunol. 2, 947-950 (2001).
    • (2001) Nat. Immunol , vol.2 , pp. 947-950
    • Schnare, M.1
  • 8
    • 58049209834 scopus 로고    scopus 로고
    • Joffre, O., Nolte, M.A., Sporri, R. & Reis e Sousa, C. Inflammatory signals in dendritic cell activation and the induction of adaptive immunity. Immunol. Rev. 227, 234-247 (2009).
    • Joffre, O., Nolte, M.A., Sporri, R. & Reis e Sousa, C. Inflammatory signals in dendritic cell activation and the induction of adaptive immunity. Immunol. Rev. 227, 234-247 (2009).
  • 9
    • 13944260898 scopus 로고    scopus 로고
    • + T cell populations lacking helper function. Nat. Immunol. 6, 163-170 (2005).
    • + T cell populations lacking helper function. Nat. Immunol. 6, 163-170 (2005).
  • 11
    • 0038307829 scopus 로고    scopus 로고
    • Pattern recognition molecules and innate immunity to parasites
    • McGuinness, D.H., Dehal, P.K. & Pleass, R.J. Pattern recognition molecules and innate immunity to parasites. Trends Parasitol. 19, 312-319 (2003).
    • (2003) Trends Parasitol , vol.19 , pp. 312-319
    • McGuinness, D.H.1    Dehal, P.K.2    Pleass, R.J.3
  • 12
    • 0037626194 scopus 로고    scopus 로고
    • Enzymatically active papain preferentially induces an allergic response in mice
    • Chambers, L. et al. Enzymatically active papain preferentially induces an allergic response in mice. Biochem. Biophys. Res. Commun. 253, 837-840 (1998).
    • (1998) Biochem. Biophys. Res. Commun , vol.253 , pp. 837-840
    • Chambers, L.1
  • 13
    • 0033388991 scopus 로고    scopus 로고
    • The cysteine protease activity of the major dust mite allergen Der p 1 selectively enhances the immunoglobulin E antibody response
    • Gough, L., Schulz, O., Sewell, H.F. & Shakib, F. The cysteine protease activity of the major dust mite allergen Der p 1 selectively enhances the immunoglobulin E antibody response. J. Exp. Med. 190, 1897-1902 (1999).
    • (1999) J. Exp. Med , vol.190 , pp. 1897-1902
    • Gough, L.1    Schulz, O.2    Sewell, H.F.3    Shakib, F.4
  • 14
    • 39449133957 scopus 로고    scopus 로고
    • A mechanism for the initiation of allergen-induced T helper type 2 responses
    • Sokol, C.L., Barton, G.M., Farr, A.G. & Medzhitov, R. A mechanism for the initiation of allergen-induced T helper type 2 responses. Nat. Immunol. 9, 310-318 (2008).
    • (2008) Nat. Immunol , vol.9 , pp. 310-318
    • Sokol, C.L.1    Barton, G.M.2    Farr, A.G.3    Medzhitov, R.4
  • 15
    • 0034877815 scopus 로고    scopus 로고
    • Analysis of type 2 immunity in vivo with a bicistronic IL-4 reporter
    • Mohrs, M., Shinkai, K., Mohrs, K. & Locksley, R.M. Analysis of type 2 immunity in vivo with a bicistronic IL-4 reporter. Immunity 15 303-311 (2001).
    • (2001) Immunity , vol.15 , pp. 303-311
    • Mohrs, M.1    Shinkai, K.2    Mohrs, K.3    Locksley, R.M.4
  • 16
    • 33947597895 scopus 로고    scopus 로고
    • Induction of Th2 type immunity in a mouse system reveals a novel immunoregulatory role of basophils
    • Oh, K., Shen, T., Le Gros, G. & Min, B. Induction of Th2 type immunity in a mouse system reveals a novel immunoregulatory role of basophils. Blood 109, 2921-2927 (2007).
    • (2007) Blood , vol.109 , pp. 2921-2927
    • Oh, K.1    Shen, T.2    Le Gros, G.3    Min, B.4
  • 17
    • 0027490172 scopus 로고
    • Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome)
    • Steimle, V., Otten, L.A., Zufferey, M. & Mach, B. Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome). Cell 75, 135-146 (1993).
    • (1993) Cell , vol.75 , pp. 135-146
    • Steimle, V.1    Otten, L.A.2    Zufferey, M.3    Mach, B.4
  • 18
    • 0028924986 scopus 로고
    • Class II transactivator regulates the expression of multiple genes involved in antigen presentation
    • Chang, C.H. & Flavell, R.A. Class II transactivator regulates the expression of multiple genes involved in antigen presentation. J. Exp. Med. 181, 765-767 (1995).
    • (1995) J. Exp. Med , vol.181 , pp. 765-767
    • Chang, C.H.1    Flavell, R.A.2
  • 19
    • 0028041568 scopus 로고
    • Class II transactivator (CIITA) is sufficient for the inducible expression of major histocompatibility complex class II genes
    • Chang, C.H., Fontes, J.D., Peterlin, M. & Flavell, R.A. Class II transactivator (CIITA) is sufficient for the inducible expression of major histocompatibility complex class II genes. J. Exp. Med. 180, 1367-1374 (1994).
    • (1994) J. Exp. Med , vol.180 , pp. 1367-1374
    • Chang, C.H.1    Fontes, J.D.2    Peterlin, M.3    Flavell, R.A.4
  • 20
    • 0030949011 scopus 로고    scopus 로고
    • Expression of MHC class II molecules in different cellular and functional compartments is controlled by differential usage of multiple promoters of the transactivator CIITA
    • Muhlethaler-Mottet, A., Otten, L.A., Steimle, V. & Mach, B. Expression of MHC class II molecules in different cellular and functional compartments is controlled by differential usage of multiple promoters of the transactivator CIITA. EMBO J. 16, 2851-2860 (1997).
    • (1997) EMBO J , vol.16 , pp. 2851-2860
    • Muhlethaler-Mottet, A.1    Otten, L.A.2    Steimle, V.3    Mach, B.4
  • 21
    • 25844499012 scopus 로고    scopus 로고
    • Regulation of MHC class II gene expression by the class II transactivator
    • Reith, W. LeibundGut-Landmann, S. & Waldburger, J.M. Regulation of MHC class II gene expression by the class II transactivator. Nat. Rev. Immunol. 5, 793-806 (2005).
    • (2005) Nat. Rev. Immunol , vol.5 , pp. 793-806
    • Reith, W.1    LeibundGut-Landmann, S.2    Waldburger, J.M.3
  • 22
    • 0033538574 scopus 로고    scopus 로고
    • The immunological synapse: A molecular machine controlling T cell activation
    • Grakoui, A. et al. The immunological synapse: A molecular machine controlling T cell activation. Science 285, 221-227 (1999).
    • (1999) Science , vol.285 , pp. 221-227
    • Grakoui, A.1
  • 23
    • 0032480279 scopus 로고    scopus 로고
    • Three-dimensional segregation of supramolecular activation clusters in T cells
    • Monks, C.R., Freiberg, B.A., Kupfer, H., Sciaky, N. & Kupfer, A. Three-dimensional segregation of supramolecular activation clusters in T cells. Nature 395, 82-86 (1998).
    • (1998) Nature , vol.395 , pp. 82-86
    • Monks, C.R.1    Freiberg, B.A.2    Kupfer, H.3    Sciaky, N.4    Kupfer, A.5
  • 24
    • 0037769037 scopus 로고    scopus 로고
    • Distinct dendritic cell populations sequentially present antigen to CD4 T cells and stimulate different aspects of cell-mediated immunity
    • Itano, A.A. et al. Distinct dendritic cell populations sequentially present antigen to CD4 T cells and stimulate different aspects of cell-mediated immunity. Immunity 19, 47-57 (2003).
    • (2003) Immunity , vol.19 , pp. 47-57
    • Itano, A.A.1
  • 25
    • 12444297666 scopus 로고    scopus 로고
    • The conduit system transports soluble antigens from the afferent lymph to resident dendritic cells in the T cell area of the lymph node
    • Sixt, M. et al. The conduit system transports soluble antigens from the afferent lymph to resident dendritic cells in the T cell area of the lymph node. Immunity 22, 19-29 (2005).
    • (2005) Immunity , vol.22 , pp. 19-29
    • Sixt, M.1
  • 26
    • 18644375874 scopus 로고    scopus 로고
    • + T cells by exogenous cell-associated antigens
    • + T cells by exogenous cell-associated antigens. Immunity 17, 211-220 (2002).
    • (2002) Immunity , vol.17 , pp. 211-220
    • Jung, S.1
  • 27
    • 19344377193 scopus 로고    scopus 로고
    • Dendritic cells maximize the memory CD8 T cell response to infection
    • Zammit, D.J., Cauley, L.S., Pham, Q.M. & Lefrancois, L. Dendritic cells maximize the memory CD8 T cell response to infection. Immunity 22, 561-570 (2005).
    • (2005) Immunity , vol.22 , pp. 561-570
    • Zammit, D.J.1    Cauley, L.S.2    Pham, Q.M.3    Lefrancois, L.4
  • 28
    • 1642362240 scopus 로고    scopus 로고
    • Type 2 immunity reflects orchestrated recruitment of cells committed to IL-4 production
    • Voehringer, D., Shinkai, K. & Locksley, R.M. Type 2 immunity reflects orchestrated recruitment of cells committed to IL-4 production. Immunity 20, 267-277 (2004).
    • (2004) Immunity , vol.20 , pp. 267-277
    • Voehringer, D.1    Shinkai, K.2    Locksley, R.M.3
  • 29
    • 0242495665 scopus 로고    scopus 로고
    • + T cell immunity. J. Immunol. 171, 5077-5084 (2003).
    • + T cell immunity. J. Immunol. 171, 5077-5084 (2003).
  • 31
    • 0032055166 scopus 로고    scopus 로고
    • Systemic overexpression of BCL-2 in the hematopoietic system protects transgenic mice from the consequences of lethal irradiation
    • Domen, J., Gandy, K.L. & Weissman, I.L. Systemic overexpression of BCL-2 in the hematopoietic system protects transgenic mice from the consequences of lethal irradiation. Blood 91, 2272-2282 (1998).
    • (1998) Blood , vol.91 , pp. 2272-2282
    • Domen, J.1    Gandy, K.L.2    Weissman, I.L.3
  • 32
    • 41549112786 scopus 로고    scopus 로고
    • Basophils play a pivotal role in immunoglobulin-G-mediated but not immunoglobulin-E-mediated systemic anaphylaxis
    • Tsujimura, Y. et al. Basophils play a pivotal role in immunoglobulin-G-mediated but not immunoglobulin-E-mediated systemic anaphylaxis. Immunity 28, 581-589 (2008).
    • (2008) Immunity , vol.28 , pp. 581-589
    • Tsujimura, Y.1
  • 33
    • 4344647601 scopus 로고    scopus 로고
    • Basophils produce IL-4 and accumulate in tissues after infection with a Th2-inducing parasite
    • Min, B. et al. Basophils produce IL-4 and accumulate in tissues after infection with a Th2-inducing parasite. J. Exp. Med. 200 507-517 (2004).
    • (2004) J. Exp. Med , vol.200 , pp. 507-517
    • Min, B.1
  • 34
    • 33745036694 scopus 로고    scopus 로고
    • Type 2 immunity is controlled by IL-4/IL-13 expression in hematopoietic non-eosinophil cells of the innate immune system
    • Voehringer, D., Reese, T.A., Huang, X., Shinkai, K. & Locksley, R.M. Type 2 immunity is controlled by IL-4/IL-13 expression in hematopoietic non-eosinophil cells of the innate immune system. J. Exp. Med. 203, 1435-1446 (2006).
    • (2006) J. Exp. Med , vol.203 , pp. 1435-1446
    • Voehringer, D.1    Reese, T.A.2    Huang, X.3    Shinkai, K.4    Locksley, R.M.5
  • 35
    • 58149218230 scopus 로고    scopus 로고
    • Basophils: A nonredundant contributor to host immunity
    • Sullivan, B.M. & Locksley, R.M. Basophils: A nonredundant contributor to host immunity. Immunity 30, 12-20 (2009).
    • (2009) Immunity , vol.30 , pp. 12-20
    • Sullivan, B.M.1    Locksley, R.M.2
  • 36
    • 24744453077 scopus 로고    scopus 로고
    • Negative control of basophil expansion by IRF-2 critical for the regulation of Th1/Th2 balance
    • Hida, S., Tadachi, M., Saito, T. & Taki, S. Negative control of basophil expansion by IRF-2 critical for the regulation of Th1/Th2 balance. Blood 106, 2011-2017 (2005).
    • (2005) Blood , vol.106 , pp. 2011-2017
    • Hida, S.1    Tadachi, M.2    Saito, T.3    Taki, S.4
  • 37
    • 45549087159 scopus 로고    scopus 로고
    • Basophils enhance immunological memory responses
    • Denzel, A. et al. Basophils enhance immunological memory responses. Nat. Immunol. 9, 733-742 (2008).
    • (2008) Nat. Immunol , vol.9 , pp. 733-742
    • Denzel, A.1
  • 38
    • 58149089720 scopus 로고    scopus 로고
    • Newly discovered roles for basophils: A neglected minority gains new respect
    • Karasuyama, H., Mukai, K., Tsujimura, Y. & Obata, K. Newly discovered roles for basophils: A neglected minority gains new respect. Nat. Rev. Immunol. 9, 9-13 (2009).
    • (2009) Nat. Rev. Immunol , vol.9 , pp. 9-13
    • Karasuyama, H.1    Mukai, K.2    Tsujimura, Y.3    Obata, K.4
  • 39
    • 0027427165 scopus 로고
    • Induction of human IgE synthesis in B cells by mast cells and basophils
    • Gauchat, J.F. et al. Induction of human IgE synthesis in B cells by mast cells and basophils. Nature 365, 340-343 (1993).
    • (1993) Nature , vol.365 , pp. 340-343
    • Gauchat, J.F.1
  • 40
    • 0031930134 scopus 로고    scopus 로고
    • Cultured basophils but not cultured mast cells induce human IgE synthesis in B cells after immunologic stimulation
    • Yanagihara, Y. et al. Cultured basophils but not cultured mast cells induce human IgE synthesis in B cells after immunologic stimulation. Clin. Exp. Immunol. 111, 136-143 (1998).
    • (1998) Clin. Exp. Immunol , vol.111 , pp. 136-143
    • Yanagihara, Y.1
  • 41
    • 11844275376 scopus 로고    scopus 로고
    • Identification of antigen-capturing cells as basophils
    • Mack, M. et al. Identification of antigen-capturing cells as basophils. J. Immunol. 174, 735-741 (2005).
    • (2005) J. Immunol , vol.174 , pp. 735-741
    • Mack, M.1
  • 42
    • 56349171260 scopus 로고    scopus 로고
    • Basophils: What they 'can do' versus what they 'actually do'
    • Min, B. Basophils: What they 'can do' versus what they 'actually do'. Nat. Immunol. 9, 1333-1339 (2008).
    • (2008) Nat. Immunol , vol.9 , pp. 1333-1339
    • Min, B.1
  • 43
    • 0037121946 scopus 로고    scopus 로고
    • Lipopolysaccharide-enhanced, toll-like receptor 4-dependent T helper cell type 2 responses to inhaled antigen
    • Eisenbarth, S.C. et al. Lipopolysaccharide-enhanced, toll-like receptor 4-dependent T helper cell type 2 responses to inhaled antigen. J. Exp. Med. 196, 1645-1651 (2002).
    • (2002) J. Exp. Med , vol.196 , pp. 1645-1651
    • Eisenbarth, S.C.1
  • 44
    • 14944375918 scopus 로고    scopus 로고
    • MyD88-dependent induction of allergic Th2 responses to intranasal antigen
    • Piggott, D.A. et al. MyD88-dependent induction of allergic Th2 responses to intranasal antigen. J. Clin. Invest. 115, 459-467 (2005).
    • (2005) J. Clin. Invest , vol.115 , pp. 459-467
    • Piggott, D.A.1
  • 45
    • 59049100417 scopus 로고    scopus 로고
    • Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein
    • Trompette, A. et al. Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein. Nature 457, 585-588 (2008).
    • (2008) Nature , vol.457 , pp. 585-588
    • Trompette, A.1
  • 46
    • 50849112477 scopus 로고    scopus 로고
    • The Nlrp3 inflammasome is critical for aluminium hydroxide-mediated IL-1beta secretion but dispensable for adjuvant activity
    • Franchi, L. & Nunez, G. The Nlrp3 inflammasome is critical for aluminium hydroxide-mediated IL-1beta secretion but dispensable for adjuvant activity. Eur. J. Immunol. 38, 2085-2089 (2008).
    • (2008) Eur. J. Immunol , vol.38 , pp. 2085-2089
    • Franchi, L.1    Nunez, G.2
  • 47
    • 47849097202 scopus 로고    scopus 로고
    • Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
    • Hornung, V. et al. Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat. Immunol. 9, 847-856 (2008).
    • (2008) Nat. Immunol , vol.9 , pp. 847-856
    • Hornung, V.1
  • 48
    • 34247106805 scopus 로고    scopus 로고
    • Aluminum hydroxide adjuvants activate caspase-1 and induce IL-1b and IL-18 release
    • Li, H., Nookala, S. & Re, F. Aluminum hydroxide adjuvants activate caspase-1 and induce IL-1b and IL-18 release. J. Immunol. 178 5271-5276 (2007).
    • (2007) J. Immunol , vol.178 , pp. 5271-5276
    • Li, H.1    Nookala, S.2    Re, F.3
  • 49
    • 47849087075 scopus 로고    scopus 로고
    • Cutting edge: Inflammasome activation by alum and alum's adjuvant effect are mediated by NLRP3
    • Li, H., Willingham, S.B., Ting, J.P. & Re, F. Cutting edge: Inflammasome activation by alum and alum's adjuvant effect are mediated by NLRP3. J. Immunol. 181, 17-21 (2008).
    • (2008) J. Immunol , vol.181 , pp. 17-21
    • Li, H.1    Willingham, S.B.2    Ting, J.P.3    Re, F.4
  • 50
    • 45749111446 scopus 로고    scopus 로고
    • Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants
    • Eisenbarth, S.C., Colegio, O.R., O'Connor, W., Sutterwala, F.S. & Flavell, R.A. Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants. Nature 453 1122-1126 (2008).
    • (2008) Nature , vol.453 , pp. 1122-1126
    • Eisenbarth, S.C.1    Colegio, O.R.2    O'Connor, W.3    Sutterwala, F.S.4    Flavell, R.A.5
  • 51
    • 34247626970 scopus 로고    scopus 로고
    • Chitin induces accumulation in tissue of innate immune cells associated with allergy
    • Reese, T.A. et al. Chitin induces accumulation in tissue of innate immune cells associated with allergy. Nature 447, 92-96 (2007).
    • (2007) Nature , vol.447 , pp. 92-96
    • Reese, T.A.1
  • 52
    • 0035882012 scopus 로고    scopus 로고
    • MacDonald, A.S., Straw, A.D., Bauman, B. & Pearce, E.J. CD8- dendritic cell activation status plays an integral role in influencing Th2 response development. J. Immunol. 167, 1982-1988 (2001).
    • MacDonald, A.S., Straw, A.D., Bauman, B. & Pearce, E.J. CD8- dendritic cell activation status plays an integral role in influencing Th2 response development. J. Immunol. 167, 1982-1988 (2001).
  • 53
    • 38949159198 scopus 로고    scopus 로고
    • Indirect involvement of allergen-captured mast cells in antigen presentation
    • Kambayashi, T. et al. Indirect involvement of allergen-captured mast cells in antigen presentation. Blood 111, 1489-1496 (2008).
    • (2008) Blood , vol.111 , pp. 1489-1496
    • Kambayashi, T.1


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