메뉴 건너뛰기




Volumn 42, Issue 1, 2015, Pages 80-94

Notch Signaling Regulates Antigen Sensitivity of Naive CD4+ T Cells by Tuning Co-stimulation

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; NOTCH RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; CD28 ANTIGEN; CYTOKINE; LYMPHOCYTE ANTIGEN RECEPTOR; MEMBRANE PROTEIN; PEPTIDE FRAGMENT; PROTEIN; SIGNAL PEPTIDE; TUMOR ANTIGEN;

EID: 84921315205     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2014.12.027     Document Type: Article
Times cited : (75)

References (57)
  • 4
    • 0031799428 scopus 로고    scopus 로고
    • Transferrin receptor in Tcell activation and transplantation
    • Bayer A.L., Baliga P., Woodward J.E. Transferrin receptor in Tcell activation and transplantation. J.Leukoc. Biol. 1998, 64:19-24.
    • (1998) J.Leukoc. Biol. , vol.64 , pp. 19-24
    • Bayer, A.L.1    Baliga, P.2    Woodward, J.E.3
  • 5
    • 0028027726 scopus 로고
    • Inhibition of proliferation and differentiation during early Tcell development by anti-transferrin receptor antibody
    • Brekelmans P., van Soest P., Leenen P.J.M., van Ewijk W. Inhibition of proliferation and differentiation during early Tcell development by anti-transferrin receptor antibody. Eur. J. Immunol. 1994, 24:2896-2902.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 2896-2902
    • Brekelmans, P.1    van Soest, P.2    Leenen, P.J.M.3    van Ewijk, W.4
  • 7
    • 34347369749 scopus 로고    scopus 로고
    • Notch signals positively regulate activity of the mTOR pathway in T-cell acute lymphoblastic leukemia
    • Chan S.M., Weng A.P., Tibshirani R., Aster J.C., Utz P.J. Notch signals positively regulate activity of the mTOR pathway in T-cell acute lymphoblastic leukemia. Blood 2007, 110:278-286.
    • (2007) Blood , vol.110 , pp. 278-286
    • Chan, S.M.1    Weng, A.P.2    Tibshirani, R.3    Aster, J.C.4    Utz, P.J.5
  • 8
    • 84875463042 scopus 로고    scopus 로고
    • Molecular mechanisms of Tcell co-stimulation and co-inhibition
    • Chen L., Flies D.B. Molecular mechanisms of Tcell co-stimulation and co-inhibition. Nat. Rev. Immunol. 2013, 13:227-242.
    • (2013) Nat. Rev. Immunol. , vol.13 , pp. 227-242
    • Chen, L.1    Flies, D.B.2
  • 9
    • 77349122994 scopus 로고    scopus 로고
    • Regulation of dendritic cell differentiation and function by Notch and Wnt pathways
    • Cheng P., Zhou J., Gabrilovich D. Regulation of dendritic cell differentiation and function by Notch and Wnt pathways. Immunol. Rev. 2010, 234:105-119.
    • (2010) Immunol. Rev. , vol.234 , pp. 105-119
    • Cheng, P.1    Zhou, J.2    Gabrilovich, D.3
  • 10
    • 24944444760 scopus 로고    scopus 로고
    • Notch promotes survival of pre-T cells at the β-selection checkpoint by regulating cellular metabolism
    • Ciofani M., Zúñiga-Pflücker J.C. Notch promotes survival of pre-T cells at the β-selection checkpoint by regulating cellular metabolism. Nat. Immunol. 2005, 6:881-888.
    • (2005) Nat. Immunol. , vol.6 , pp. 881-888
    • Ciofani, M.1    Zúñiga-Pflücker, J.C.2
  • 11
    • 0020678796 scopus 로고
    • Simultaneous flow cytometric analysis of human Tcell activation antigen expression and DNA content
    • Cotner T., Williams J.M., Christenson L., Shapiro H.M., Strom T.B., Strominger J. Simultaneous flow cytometric analysis of human Tcell activation antigen expression and DNA content. J.Exp. Med. 1983, 157:461-472.
    • (1983) J.Exp. Med. , vol.157 , pp. 461-472
    • Cotner, T.1    Williams, J.M.2    Christenson, L.3    Shapiro, H.M.4    Strom, T.B.5    Strominger, J.6
  • 13
    • 34547829276 scopus 로고    scopus 로고
    • Controlling cell growth and survival through regulated nutrient transporter expression
    • Edinger A.L. Controlling cell growth and survival through regulated nutrient transporter expression. Biochem. J. 2007, 406:1-12.
    • (2007) Biochem. J. , vol.406 , pp. 1-12
    • Edinger, A.L.1
  • 14
    • 34547922380 scopus 로고    scopus 로고
    • Delta-Notch-and then? Protein interactions and proposed modes of repression by Hes and Hey bHLH factors
    • Fischer A., Gessler M. Delta-Notch-and then? Protein interactions and proposed modes of repression by Hes and Hey bHLH factors. Nucleic Acids Res. 2007, 35:4583-4596.
    • (2007) Nucleic Acids Res. , vol.35 , pp. 4583-4596
    • Fischer, A.1    Gessler, M.2
  • 17
    • 0021719897 scopus 로고
    • Resting and sensitized T lymphocytes exhibit distinct stimulatory (antigen-presenting cell) requirements for growth and lymphokine release
    • Inaba K., Steinman R.M. Resting and sensitized T lymphocytes exhibit distinct stimulatory (antigen-presenting cell) requirements for growth and lymphokine release. J.Exp. Med. 1984, 160:1717-1735.
    • (1984) J.Exp. Med. , vol.160 , pp. 1717-1735
    • Inaba, K.1    Steinman, R.M.2
  • 19
    • 0030846262 scopus 로고    scopus 로고
    • Single cell analysis reveals regulated hierarchical Tcell antigen receptor signaling thresholds and intraclonal heterogeneity for individual cytokine responses of CD4+ Tcells
    • Itoh Y., Germain R.N. Single cell analysis reveals regulated hierarchical Tcell antigen receptor signaling thresholds and intraclonal heterogeneity for individual cytokine responses of CD4+ Tcells. J.Exp. Med. 1997, 186:757-766.
    • (1997) J.Exp. Med. , vol.186 , pp. 757-766
    • Itoh, Y.1    Germain, R.N.2
  • 20
    • 44449165597 scopus 로고    scopus 로고
    • Glucose uptake is limiting in Tcell activation and requires CD28-mediated Akt-dependent and independent pathways
    • Jacobs S.R., Herman C.E., Maciver N.J., Wofford J.A., Wieman H.L., Hammen J.J., Rathmell J.C. Glucose uptake is limiting in Tcell activation and requires CD28-mediated Akt-dependent and independent pathways. J.Immunol. 2008, 180:4476-4486.
    • (2008) J.Immunol. , vol.180 , pp. 4476-4486
    • Jacobs, S.R.1    Herman, C.E.2    Maciver, N.J.3    Wofford, J.A.4    Wieman, H.L.5    Hammen, J.J.6    Rathmell, J.C.7
  • 21
    • 0033556251 scopus 로고    scopus 로고
    • Cutting edge: protective effects of notch-1 on TCR-induced apoptosis
    • Jehn B.M., Bielke W., Pear W.S., Osborne B.A. Cutting edge: protective effects of notch-1 on TCR-induced apoptosis. J.Immunol. 1999, 162:635-638.
    • (1999) J.Immunol. , vol.162 , pp. 635-638
    • Jehn, B.M.1    Bielke, W.2    Pear, W.S.3    Osborne, B.A.4
  • 22
    • 43449128845 scopus 로고    scopus 로고
    • Influencing the fates of CD4 Tcells on the path to memory: lessons from influenza
    • Jelley-Gibbs D.M., Strutt T.M., McKinstry K.K., Swain S.L. Influencing the fates of CD4 Tcells on the path to memory: lessons from influenza. Immunol. Cell Biol. 2008, 86:343-352.
    • (2008) Immunol. Cell Biol. , vol.86 , pp. 343-352
    • Jelley-Gibbs, D.M.1    Strutt, T.M.2    McKinstry, K.K.3    Swain, S.L.4
  • 25
    • 77954989425 scopus 로고    scopus 로고
    • HIV-1 Rev-binding protein accelerates cellular uptake of iron to drive Notch-induced Tcell leukemogenesis in mice
    • Khwaja S.S., Liu H., Tong C., Jin F., Pear W.S., van Deursen J., Bram R.J. HIV-1 Rev-binding protein accelerates cellular uptake of iron to drive Notch-induced Tcell leukemogenesis in mice. J.Clin. Invest. 2010, 120:2537-2548.
    • (2010) J.Clin. Invest. , vol.120 , pp. 2537-2548
    • Khwaja, S.S.1    Liu, H.2    Tong, C.3    Jin, F.4    Pear, W.S.5    van Deursen, J.6    Bram, R.J.7
  • 26
    • 84858257263 scopus 로고    scopus 로고
    • Dual targeting strategies with bispecific antibodies
    • Kontermann R.E. Dual targeting strategies with bispecific antibodies. MAbs 2012, 4:182-197.
    • (2012) MAbs , vol.4 , pp. 182-197
    • Kontermann, R.E.1
  • 27
    • 0033534678 scopus 로고    scopus 로고
    • From TCR engagement to Tcell activation: a kinetic view of Tcell behavior
    • Lanzavecchia A., Iezzi G., Viola A. From TCR engagement to Tcell activation: a kinetic view of Tcell behavior. Cell 1999, 96:1-4.
    • (1999) Cell , vol.96 , pp. 1-4
    • Lanzavecchia, A.1    Iezzi, G.2    Viola, A.3
  • 28
    • 0026017971 scopus 로고
    • Interleukin-2 programs mouse alpha beta T lymphocytes for apoptosis
    • Lenardo M.J. Interleukin-2 programs mouse alpha beta T lymphocytes for apoptosis. Nature 1991, 353:858-861.
    • (1991) Nature , vol.353 , pp. 858-861
    • Lenardo, M.J.1
  • 29
    • 84872790689 scopus 로고    scopus 로고
    • Interleukin-2 at the crossroads of effector responses, tolerance, and immunotherapy
    • Liao W., Lin J.X., Leonard W.J. Interleukin-2 at the crossroads of effector responses, tolerance, and immunotherapy. Immunity 2013, 38:13-25.
    • (2013) Immunity , vol.38 , pp. 13-25
    • Liao, W.1    Lin, J.X.2    Leonard, W.J.3
  • 30
    • 0034663892 scopus 로고    scopus 로고
    • Opening a window on thymic positive selection: developmental changes in the influence of cosignaling by integrins and CD28 on selection events induced by TCR engagement
    • Lucas B., Germain R.N. Opening a window on thymic positive selection: developmental changes in the influence of cosignaling by integrins and CD28 on selection events induced by TCR engagement. J.Immunol. 2000, 165:1889-1895.
    • (2000) J.Immunol. , vol.165 , pp. 1889-1895
    • Lucas, B.1    Germain, R.N.2
  • 33
    • 84868304869 scopus 로고    scopus 로고
    • Canonical and non-canonical notch signaling in CD4+ Tcells
    • Berlin Heidelberg: Springer, F. Radtke (Ed.)
    • Minter L.M., Osborne B.A. Canonical and non-canonical notch signaling in CD4+ Tcells. Notch Regulation of the Immune System 2012, 99-114. Berlin Heidelberg: Springer. F. Radtke (Ed.).
    • (2012) Notch Regulation of the Immune System , pp. 99-114
    • Minter, L.M.1    Osborne, B.A.2
  • 35
    • 67649216137 scopus 로고    scopus 로고
    • Regulation of Tcell activation by Notch ligand, DLL4, promotes IL-17 production and Rorc activation
    • Mukherjee S., Schaller M.A., Neupane R., Kunkel S.L., Lukacs N.W. Regulation of Tcell activation by Notch ligand, DLL4, promotes IL-17 production and Rorc activation. J.Immunol. 2009, 182:7381-7388.
    • (2009) J.Immunol. , vol.182 , pp. 7381-7388
    • Mukherjee, S.1    Schaller, M.A.2    Neupane, R.3    Kunkel, S.L.4    Lukacs, N.W.5
  • 36
    • 0032143421 scopus 로고    scopus 로고
    • Mice with a fluorescent marker for interleukin 2 gene activation
    • Naramura M., Hu R.J., Gu H. Mice with a fluorescent marker for interleukin 2 gene activation. Immunity 1998, 9:209-216.
    • (1998) Immunity , vol.9 , pp. 209-216
    • Naramura, M.1    Hu, R.J.2    Gu, H.3
  • 39
    • 0034600901 scopus 로고    scopus 로고
    • Negative regulation of Tcell proliferation and interleukin 2 production by the serine threonine kinase GSK-3
    • Ohteki T., Parsons M., Zakarian A., Jones R.G., Nguyen L.T., Woodgett J.R., Ohashi P.S. Negative regulation of Tcell proliferation and interleukin 2 production by the serine threonine kinase GSK-3. J.Exp. Med. 2000, 192:99-104.
    • (2000) J.Exp. Med. , vol.192 , pp. 99-104
    • Ohteki, T.1    Parsons, M.2    Zakarian, A.3    Jones, R.G.4    Nguyen, L.T.5    Woodgett, J.R.6    Ohashi, P.S.7
  • 40
    • 50949091487 scopus 로고    scopus 로고
    • Notch and presenilin regulate cellular expansion and cytokine secretion but cannot instruct Th1/Th2 fate acquisition
    • Ong C.T., Sedy J.R., Murphy K.M., Kopan R. Notch and presenilin regulate cellular expansion and cytokine secretion but cannot instruct Th1/Th2 fate acquisition. PLoS ONE 2008, 3:e2823.
    • (2008) PLoS ONE , vol.3 , pp. e2823
    • Ong, C.T.1    Sedy, J.R.2    Murphy, K.M.3    Kopan, R.4
  • 44
    • 84903277871 scopus 로고    scopus 로고
    • Integrating canonical and metabolic signalling programmes in the regulation of Tcell responses
    • Pollizzi K.N., Powell J.D. Integrating canonical and metabolic signalling programmes in the regulation of Tcell responses. Nat. Rev. Immunol. 2014, 14:435-446.
    • (2014) Nat. Rev. Immunol. , vol.14 , pp. 435-446
    • Pollizzi, K.N.1    Powell, J.D.2
  • 46
    • 78049310884 scopus 로고    scopus 로고
    • CD28 co-signaling in the adaptive immune response
    • Riha P., Rudd C.E. CD28 co-signaling in the adaptive immune response. Self Nonself 2010, 1:231-240.
    • (2010) Self Nonself , vol.1 , pp. 231-240
    • Riha, P.1    Rudd, C.E.2
  • 47
    • 0029815848 scopus 로고    scopus 로고
    • A dynamic assembly of diverse transcription factors integrates activation and cell-type information for interleukin 2 gene regulation
    • Rothenberg E.V., Ward S.B. A dynamic assembly of diverse transcription factors integrates activation and cell-type information for interleukin 2 gene regulation. Proc. Natl. Acad. Sci. USA 1996, 93:9358-9365.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 9358-9365
    • Rothenberg, E.V.1    Ward, S.B.2
  • 48
    • 52649179291 scopus 로고    scopus 로고
    • Notch1 and TGFbeta1 cooperatively regulate Foxp3 expression and the maintenance of peripheral regulatory Tcells
    • Samon J.B., Champhekar A., Minter L.M., Telfer J.C., Miele L., Fauq A., Das P., Golde T.E., Osborne B.A. Notch1 and TGFbeta1 cooperatively regulate Foxp3 expression and the maintenance of peripheral regulatory Tcells. Blood 2008, 112:1813-1821.
    • (2008) Blood , vol.112 , pp. 1813-1821
    • Samon, J.B.1    Champhekar, A.2    Minter, L.M.3    Telfer, J.C.4    Miele, L.5    Fauq, A.6    Das, P.7    Golde, T.E.8    Osborne, B.A.9
  • 50
    • 77956107505 scopus 로고    scopus 로고
    • Ameliorating effects of anti-Dll4 mAb on Theiler's murine encephalomyelitis virus-induced demyelinating disease
    • Takeichi N., Yanagisawa S., Kaneyama T., Yagita H., Jin Y.H., Kim B.S., Koh C.S. Ameliorating effects of anti-Dll4 mAb on Theiler's murine encephalomyelitis virus-induced demyelinating disease. Int. Immunol. 2010, 22:729-738.
    • (2010) Int. Immunol. , vol.22 , pp. 729-738
    • Takeichi, N.1    Yanagisawa, S.2    Kaneyama, T.3    Yagita, H.4    Jin, Y.H.5    Kim, B.S.6    Koh, C.S.7
  • 51
    • 2442522357 scopus 로고    scopus 로고
    • Regulation of alphabeta/gammadelta Tcell lineage commitment and peripheral Tcell responses by Notch/RBP-J signaling
    • Tanigaki K., Tsuji M., Yamamoto N., Han H., Tsukada J., Inoue H., Kubo M., Honjo T. Regulation of alphabeta/gammadelta Tcell lineage commitment and peripheral Tcell responses by Notch/RBP-J signaling. Immunity 2004, 20:611-622.
    • (2004) Immunity , vol.20 , pp. 611-622
    • Tanigaki, K.1    Tsuji, M.2    Yamamoto, N.3    Han, H.4    Tsukada, J.5    Inoue, H.6    Kubo, M.7    Honjo, T.8
  • 52
    • 0031563160 scopus 로고    scopus 로고
    • High concentrations of antigenic ligand activate and do not tolerize naive CD4 Tcells in the absence of CD28/B7 costimulation
    • Teh H.S., Teh S.J. High concentrations of antigenic ligand activate and do not tolerize naive CD4 Tcells in the absence of CD28/B7 costimulation. Cell. Immunol. 1997, 179:74-83.
    • (1997) Cell. Immunol. , vol.179 , pp. 74-83
    • Teh, H.S.1    Teh, S.J.2
  • 55
    • 79953310550 scopus 로고    scopus 로고
    • White paper on adoptive cell therapy for cancer with tumor-infiltrating lymphocytes: a report of the CTEP subcommittee on adoptive cell therapy
    • Weber J., Atkins M., Hwu P., Radvanyi L., Sznol M., Yee C. White paper on adoptive cell therapy for cancer with tumor-infiltrating lymphocytes: a report of the CTEP subcommittee on adoptive cell therapy. Clin. Cancer Res. 2011, 17:1664-1673. Immunotherapy Task Force of the NCI Investigational Drug Steering Committee.
    • (2011) Clin. Cancer Res. , vol.17 , pp. 1664-1673
    • Weber, J.1    Atkins, M.2    Hwu, P.3    Radvanyi, L.4    Sznol, M.5    Yee, C.6
  • 56
    • 0031437624 scopus 로고    scopus 로고
    • Following the fate of individual Tcells throughout activation and clonal expansion. Signals from Tcell receptor and CD28 differentially regulate the induction and duration of a proliferative response
    • Wells A.D., Gudmundsdottir H., Turka L.A. Following the fate of individual Tcells throughout activation and clonal expansion. Signals from Tcell receptor and CD28 differentially regulate the induction and duration of a proliferative response. J.Clin. Invest. 1997, 100:3173-3183.
    • (1997) J.Clin. Invest. , vol.100 , pp. 3173-3183
    • Wells, A.D.1    Gudmundsdottir, H.2    Turka, L.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.