Dissecting genetic and environmental mutation signatures with model organisms

Trends in Genetics

Volumn 31, Issue 8, 2015, Pages 465-474

  Segovia, Romulo ^a,b   Tam, Annie S ^a,b   Stirling, Peter C ^a,b  

^a BRITISH COLUMBIA CANCER AGENCY   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Cancer genomics; Deep sequencing; Model organisms; Mutagens; Mutation signature

Indexed keywords

AFLATOXIN; CARCINOGEN; CISPLATIN; DNA; DNA POLYMERASE; MUTAGENIC AGENT; TOBACCO SMOKE;

ARABIDOPSIS THALIANA; BACTERIUM; CAENORHABDITIS ELEGANS; CANCER CELL; CANCER GENOME; CARCINOGENESIS; CELL CYCLE; DNA DAMAGE; DNA REPAIR; DROSOPHILA MELANOGASTER; ESCHERICHIA COLI; EVOLUTION; EXCISION REPAIR; GENE EXPRESSION; GENE MUTATION; GENOME; HUMAN; MISMATCH REPAIR; MUTATION RATE; MUTATIONAL ANALYSIS; NEMATODE; NONHUMAN; ORGANISMS; PRIORITY JOURNAL; REVIEW; SACCHAROMYCES CEREVISIAE; YEAST; ANIMAL; BIOLOGICAL MODEL; ENVIRONMENT; GENETICS; HIGH THROUGHPUT SEQUENCING; MUTATION; NEOPLASM;

ANIMALS; ENVIRONMENT; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; MODELS, BIOLOGICAL; MUTATION; MUTATION RATE; NEOPLASMS;

EID: 84938292675     PISSN: 01689525     EISSN: 13624555     Source Type: Journal    
DOI: 10.1016/j.tig.2015.04.001     Document Type: Review

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