C. elegans whole-genome sequencing reveals mutational signatures related to carcinogens and DNA repair deficiency

Genome Research

Volumn 24, Issue 10, 2014, Pages 1624-1636

  Meier, Bettina ^a   Cooke, Susanna L ^b   Weiss, Joerg ^a   Bailly, Aymeric P ^a,c   Alexandrov, Ludmil B ^b   Marshall, John ^b   Raine, Keiran ^b   Maddison, Mark ^b   Anderson, Elizabeth ^b   Stratton, Michael R ^b   Gartner, Anton ^a   Campbell, Peter J ^b,d,e  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^c UNIV MONTPELLIER   (France)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^e ADDENBROOKE S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AFLATOXIN B1; CARCINOGEN; CHLORMETHINE; CISPLATIN; GUANINE DERIVATIVE; CAENORHABDITIS ELEGANS PROTEIN; DNA HELICASE; MRT-2 PROTEIN, C ELEGANS; XPF-1 PROTEIN, C ELEGANS;

ADULT; ANIMAL EXPERIMENT; ARTICLE; CAENORHABDITIS ELEGANS; CARCINOGEN DNA INTERACTION; CARCINOGENICITY; CHROMOSOME REARRANGEMENT; CONTROLLED STUDY; CPG ISLAND; DISORDERS OF DNA SYNTHESIS AND REPAIR; DNA CROSS LINKING; DNA REPLICATION; DNA STRAND BREAKAGE; EXCISION REPAIR; EXPERIMENTAL MODEL; FEMALE; GENE CLUSTER; GENOTYPE; INDEL MUTATION; LIVER CARCINOGENESIS; MALE; MICROBIAL GENOME; MUTAGENICITY; MUTATION RATE; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; TELOMERE; ANIMAL; ANIMAL MODEL; DNA REPAIR; DNA SEQUENCE; DRUG EFFECTS; GENETICS; GENOME; MUTATION; PROCEDURES;

ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CARCINOGENS; DNA HELICASES; DNA REPAIR; GENOME; MODELS, ANIMAL; MUTATION; SEQUENCE ANALYSIS, DNA;

EID: 84907481031     PISSN: 10889051     EISSN: 15495469     Source Type: Journal    
DOI: 10.1101/gr.175547.114     Document Type: Article

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